BGC0002019: tiancilactone A biosynthetic gene cluster from Streptomyces sp. CB03234
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Location: 1 - 24,752 nt. (total: 24,752 nt).
This entry is originally from NCBI GenBank BK010469.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002019
Short description tiancilactone A biosynthetic gene cluster from Streptomyces sp. CB03234
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Terpene
Loci NCBI GenBank: BK010469.1
Compounds
  • tiancilactone A
  • tiancilactone B
  • tiancilactone C
  • tiancilactone D
  • tiancilactone E
  • tiancilactone F
  • tiancilactone G
  • tiancilactone H
Species Streptomyces sp. CB03234 [taxonomy]
References
Chemical products information
tiancilactone A
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C32H44Cl1N1O8
Chemical database entries
PubCHEM
tiancilactone B
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C32H45N1O8
Chemical database entries
PubCHEM
tiancilactone C
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C32H44Cl1N1O8
Chemical database entries
PubCHEM
tiancilactone D
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C34H49Cl1N2O8
Chemical database entries
PubCHEM
tiancilactone E
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C35H51Cl1N2O8
Chemical database entries
PubCHEM
tiancilactone F
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C31H44Cl1N1O6
Chemical database entries
PubCHEM
tiancilactone G
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C30H46Cl1N1O5
Chemical database entries
PubCHEM
tiancilactone H
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C22H34O4
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • DAC74128.1
 1 - 1296 (+) Na/H exchanger
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  • DAC74129.1
 1387 - 1605 (+) LuxR family regulator
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  • DAC74131.1
 1676 - 2542 (-) alpha-ketoglutarate-dependent dioxygenase
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  • DAC74130.1
 2568 - 3830 (-) FAD-dependent GGPP epoxidase
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  • DAC74132.1
 3857 - 5671 (-) type II diterpene synthase
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  • DAC74133.1
 5691 - 6710 (-) UbiA-type prenyltransferase
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  • DAC74134.1
 6712 - 7743 (-) GGPP synthase
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  • DAC74135.1
 7747 - 8598 (-) fumarylacetoacetate-like hydrolase
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  • DAC74136.1
 8644 - 9786 (-) cytochrome P450
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  • DAC74137.1
 10342 - 11841 (+) AMP-dependent synthetase
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  • DAC74138.1
 11828 - 12103 (+) peptide carrier protein
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  • DAC74139.1
 12281 - 13426 (+) cytochrome P450
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  • DAC74140.1
 13459 - 14307 (+) alpha beta hydrolase
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  • DAC74141.1
 14342 - 15055 (+) tryptophan dioxygenase
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  • DAC74150.1
 15112 - 16581 (+) tryptophan halogenase
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  • DAC74142.1
 16629 - 17222 (-) TetR family regulator
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  • DAC74143.1
 17367 - 18527 (+) cytochrome P450
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  • DAC74144.1
 18649 - 19473 (+) methyltransferase
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  • DAC74145.1
 19588 - 20397 (+) methyltransferase
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  • DAC74146.1
 20456 - 21451 (+) NAD-dependent epimerase/dehydratase
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  • DAC74147.1
 21456 - 22277 (+) methyltransferase
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  • DAC74148.1
 22341 - 23480 (-) alpha beta hydrolase
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  • DAC74149.1
 23541 - 24752 (-) pyridoxal-dependent decarboxylase
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Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: SJG3CBEHSM6A3I74YXLH6GLA, no GDPR consent given).
  • Add compound details
  • Added AMP-binding domain substrate specificities
Similar known gene clusters
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