BGC0002024: nargenicin biosynthetic gene cluster from Nocardia argentinensis
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Location: 1 - 69,359 nt. (total: 69,359 nt).
This entry is originally from NCBI GenBank MH544245.1.

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core biosynthetic genes
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Gene details
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General
Compounds
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002024
Short description nargenicin biosynthetic gene cluster from Nocardia argentinensis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: MH544245.1
Compounds
  • nargenicin
Species Nocardia argentinensis [taxonomy]
References
Chemical products information
nargenicin
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AXG22400.1
 1 - 183 (-) hypothetical protein
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  • AXG22401.1
 309 - 620 (+) hypothetical protein
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  • AXG22402.1
 652 - 4212 (-) DNA polymerase III subunit alpha
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  • AXG22403.1
  • ngnE
 4339 - 5118 (-) thioesterase
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  • AXG22404.1
  • ngnD
 5198 - 5656 (-) nuclear transport factor 2 family protein
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  • AXG22405.1
  • ngnC
 5653 - 16644 (-) type I polyketide synthase
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  • AXG22406.1
  • ngnB
 16660 - 30948 (-) type I polyketide synthase
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  • AXG22407.1
  • ngnA
 30996 - 48881 (-) type I polyketide synthase
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  • AXG22408.1
  • ngnK
 49202 - 50248 (-) L-glyceraldehyde 3-phosphate reductase
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  • AXG22409.1
  • ngnP1
 50439 - 51701 (+) cytochrome P450
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  • AXG22410.1
  • ngnO2
 51720 - 52985 (+) pristinamycin IIA synthase subunit A
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  • AXG22411.1
  • ngnO1
 52982 - 53914 (+) LLM class flavin-dependent oxidoreductase
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  • AXG22412.1
  • ngnG
 53952 - 54794 (+) short-chain dehydrogenase
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  • AXG22413.1
  • ngnM
 54856 - 55692 (-) methyltransferase
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  • AXG22414.1
  • ngnF
 55721 - 55918 (-) ferredoxin
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  • AXG22415.1
  • ngnP2
 55925 - 57142 (-) Cytochrome P450
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  • AXG22416.1
  • ngnO3
 57330 - 58127 (+) Phytanoyl-CoA dioxygenase
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  • AXG22417.1
  • ngnI
 58153 - 59079 (+) retinol dehydrogenase
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  • AXG22418.1
  • ngnJ
 59093 - 60040 (-) LysR family transcriptional regulator
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  • AXG22419.1
  • ngnN5
 61174 - 61449 (-) proline carrier protein
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  • AXG22420.1
  • ngnN4
 61388 - 62950 (-) proline adenyltransferase
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  • AXG22421.1
  • ngnN3
 62947 - 64074 (-) prolyl carrier protein dehydrogenase
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  • AXG22422.1
  • ngnN2
 64355 - 65332 (+) keto-acyl ACP-synthase
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  • AXG22423.1
 65890 - 67326 (+) peptidase M14
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  • AXG22424.1
 67693 - 68781 (+) GGDEF domain-containing protein
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  • AXG22425.1
 68820 - 69359 (+) acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
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Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added AMP-binding domain substrate specificities
Detailed domain annotation
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