BGC0002026: thaxteramide A1 biosynthetic gene cluster from Jahnella sp. MSr9139
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Location: 1 - 57,257 nt. (total: 57,257 nt).
This entry is originally from NCBI GenBank MK551162.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002026
Short description thaxteramide A1 biosynthetic gene cluster from Jahnella sp. MSr9139
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: MK551162.1
Compounds
  • thaxteramide A1
  • thaxteramide A2
  • thaxteramide B1
  • thaxteramide B2
Species Jahnella sp. MSr9139 [taxonomy]
References
Chemical products information
thaxteramide A1
(no structure information available)
thaxteramide A2
(no structure information available)
thaxteramide B1
(no structure information available)
thaxteramide B2
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QDA77054.1
 220 - 1590 (+) PAS/PAC sensor protein
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  • QDA77055.1
 1897 - 2754 (+) signal peptide protein
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  • QDA77056.1
 2782 - 3441 (-) imidazole glycerol phosphate synthase subunit
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  • QDA77057.1
 3443 - 4030 (-) HisB protein
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  • QDA77058.1
  • thxA1
 4355 - 13003 (+) polyketide synthase
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  • QDA77059.1
  • thxA2
 13014 - 41873 (+) polyketide synthase/nonribosomal peptide synthetase
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  • QDA77060.1
 42481 - 43359 (+) secreted protein
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  • QDA77061.1
 43429 - 45849 (+) Lon protease 2
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  • QDA77062.1
 45868 - 48204 (+) hypothetical protein
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  • QDA77063.1
 48220 - 50769 (+) two-component hybrid sensor and regulator
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  • QDA77064.1
 50821 - 52578 (-) multi-sensor hybrid histidine kinase
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  • QDA77065.1
 52697 - 53482 (-) exodeoxyribonuclease III
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  • QDA77066.1
 53589 - 55292 (-) hypothetical protein
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  • QDA77067.1
 55289 - 56581 (-) histidyl-tRNA synthetase
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  • QDA77068.1
 56763 - 57197 (+) Holliday junction resolvase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
thxA2
Module ?
Specificity: serine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: tyrosine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: beta-alanine / 3R-methylbeta-alanine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: tyrosine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: CUSGWVK3I4TVHJH7NHPFAP2L, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added missing polyketide class
  • Added NRP substrate specificities
Detailed domain annotation
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