BGC0002028: frigocyclinone biosynthetic gene cluster from Streptomyces griseus
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Location: 1 - 35,202 nt. (total: 35,202 nt).
This entry is originally from NCBI GenBank MK240316.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002028
Short description frigocyclinone biosynthetic gene cluster from Streptomyces griseus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MK240316.1
849 - 34300
via
Compounds
  • frigocyclinone
Species Streptomyces griseus [taxonomy]
References
Chemical products information
frigocyclinone Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QDG00807.1
 849 - 1982 (+) glycosyl transferase
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    • QDG00808.1
    		 2058 - 3677 (+) drug resistance transporter
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      • QDG00809.1
      		 4019 - 4951 (+) N,N-dimethyltransferase
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        • QDG00810.1
        		 5248 - 6177 (+) NDP-hexose aminotransferase
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          • QDG00811.1
          		 6181 - 6771 (+) NDP-hexose 35-epimerase
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            • QDG00812.1
            		 6970 - 7851 (+) glucose-1-phosphate thymidylyltransferase
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              • QDG00813.1
              		 7896 - 8864 (+) dTDP-glucose 46-dehydratase
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                • QDG00814.1
                		 8861 - 10165 (+) NDP-hexose 34-dehydratase
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                  • QDG00815.1
                  		 10162 - 11544 (+) NDP-hexose 23-dehydratase
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                    • QDG00816.1
                    		 11610 - 12503 (+) dNDP-hexose 3-ketoreductase
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                      • QDG00817.1
                      		 12562 - 13785 (+) putative methyltransferase
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                        • QDG00818.1
                        		 13901 - 14770 (+) putative adenosine kinase
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                          • QDG00819.1
                          		 14767 - 15636 (+) methylenetetrahydrofolate reductase
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                            • QDG00820.1
                            		 16015 - 17007 (-) thioesterase
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                              • QDG00821.1
                              		 17134 - 19470 (-) oxygenase-reductase
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                                • QDG00822.1
                                		 19473 - 20429 (-) aromatase/cyclase
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                                  • QDG00823.1
                                  		 20429 - 21211 (-) polyketide ketoreductase
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                                    • QDG00824.1
                                    		 21285 - 21581 (-) acyl carrier protein
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                                      • QDG00825.1
                                      		 21666 - 22883 (-) chain length factor
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                                        • QDG00826.1
                                        		 22880 - 24148 (-) beta-ketoacyl synthase
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                                          • QDG00827.1
                                          		 24186 - 24749 (-) polyketide cyclase
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                                            • QDG00828.1
                                            		 24722 - 26254 (-) FAD-binding protein
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                                              • QDG00829.1
                                              		 26678 - 27484 (-) two-component system response regulator
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                                                • QDG00830.1
                                                		 28597 - 29577 (-) quinone oxidoreductase protein
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                                                  • QDG00831.1
                                                  		 29630 - 30208 (-) hypothetical protein
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                                                    • QDG00832.1
                                                    		 30532 - 31230 (+) hypothetical protein
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                                                      • QDG00833.1
                                                      		 31542 - 32075 (-) hypothetical protein
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                                                        • QDG00834.1
                                                        		 32375 - 33361 (-) two-component system response regulator
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                                                          • QDG00835.1
                                                          		 33491 - 34300 (+) tetr family transcriptional regulator
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                                                            Biosynthesis information

                                                            No biosynthesis information available for this record.

                                                            Annotation changelog

                                                            Entry version: 3

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2022-10-07
                                                            Update chemical activity to schema version 2.11
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 2

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2022-09-15
                                                            Updated bioactivity data
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 1

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2019-10-16
                                                            Submitted
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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