BGC0002028 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002028 (Streptomyces griseus)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T2PKS	1	35,202	High	frigocyclinone	PKS

BGC0002028 - Region 1 - T2PKS

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Location: 1 - 35,202 nt. (total: 35,202 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 35,203
Label		BGC0002028

Tailoring functions

Oxidoreductases: dehydrogenase oxidoreductase oxygenase

QDG00816.1: oxidoreductase

smcogs: SMCOG1079: oxidoreductase

QDG00821.1: monooxygenase FAD-binding

smcogs: SMCOG1050: monooxygenase FAD-binding

QDG00823.1: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

QDG00828.1: monooxygenase FAD-binding

smcogs: SMCOG1050: monooxygenase FAD-binding

QDG00830.1: crotonyl-CoA reductase / alcohol dehydrogenase

smcogs: SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase

Transferases: aminotransferase glycosyltransferase kinase methyltransferase transferase

QDG00807.1: glycosyltransferase, MGT family

smcogs: SMCOG1062: glycosyltransferase, MGT family

QDG00809.1: methyltransferase

smcogs: SMCOG1248: methyltransferase

QDG00810.1: DegT/DnrJ/EryC1/StrS aminotransferase

smcogs: SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase

QDG00812.1: glucose-1-phosphate adenylyl/thymidylyltransferase

smcogs: SMCOG1064: glucose-1-phosphate adenylyl/thymidylyltransferase

QDG00814.1: DegT/DnrJ/EryC1/StrS aminotransferase

smcogs: SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase

QDG00818.1: PfkB domain protein

smcogs: SMCOG1276: PfkB domain protein

Lyases: cyclase dehydratase

QDG00813.1: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

QDG00822.1: cyclase/dehydrase

smcogs: SMCOG1128: cyclase/dehydrase

QDG00827.1: Polyketide synthesis cyclase

smcogs: SMCOG1225: Polyketide synthesis cyclase

Ligases: synthase

QDG00825.1: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

QDG00826.1: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002028.4	1.00	PKS	frigocyclinone	Streptomyces griseus
BGC0000231.5	0.83	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0001723.5	0.78	PKS	oviedomycin	Streptomyces antibioticus
BGC0000234.5	0.77	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000278.3	0.64	PKS	urdamycin	Streptomyces fradiae
BGC0000235.5	0.63	PKS	kiamycin	Streptomyces sp. W007
BGC0000253.4	0.63	PKS	oviedomycin	Streptomyces antibioticus
BGC0001817.5	0.63	other (other)	vancosamine	Streptomyces sp. WAC2288
BGC0002276.2	0.63	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000236.5	0.61	PKS	kinamycin	Streptomyces murayamaensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002028.4	1.00	PKS	frigocyclinone	Streptomyces griseus
BGC0000231.5	0.83	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0001723.5	0.78	PKS	oviedomycin	Streptomyces antibioticus
BGC0000234.5	0.77	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000278.3	0.64	PKS	urdamycin	Streptomyces fradiae
BGC0000235.5	0.63	PKS	kiamycin	Streptomyces sp. W007
BGC0000253.4	0.63	PKS	oviedomycin	Streptomyces antibioticus
BGC0001817.5	0.63	other (other)	vancosamine	Streptomyces sp. WAC2288
BGC0002276.2	0.63	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000236.5	0.61	PKS	kinamycin	Streptomyces murayamaensis

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 35202
Starter unit(s):: acetyl-CoA (Score: 0.0; E-value: 0)
Malonyl elongations:: 8|9 (Score: 687.7; E-value: 9.8e-210)
Product class(es):: angucycline
Product molecular weight(s):: acetyl-CoA_8: 531 Da
acetyl-CoA_9: 573 Da

QDG00807.1: GT (Score: 371.8; E-value: 1.2e-113)
QDG00821.1: KR C15 (Score: 494.8; E-value: 1.1e-151)
QDG00822.1: CYC C7-C12 (Score: 508.7; E-value: 1e-155)
QDG00823.1: KR C9 (Score: 482.0; E-value: 9.6e-148)
QDG00824.1: ACP (Score: 121.8; E-value: 2.1e-38)
QDG00825.1: CLF 8|9 (Score: 687.7; E-value: 9.8e-210)
QDG00826.1: KS (Score: 797.6; E-value: 5.3e-243)
QDG00827.1: CYC C4-C17/C2-C19 (Score: 199.3; E-value: 1.4e-61)
QDG00828.1: OXY (Score: 607.8; E-value: 3.4e-185)