BGC0002028: frigocyclinone biosynthetic gene cluster from Streptomyces griseus
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Location: 849 - 34,300 nt. (total: 33,452 nt).
This entry is originally from NCBI GenBank MK240316.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002028
Short description frigocyclinone biosynthetic gene cluster from Streptomyces griseus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: MK240316.1
Compounds
  • frigocyclinone
Species Streptomyces griseus [taxonomy]
References
Chemical products information
frigocyclinone
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QDG00807.1
 849 - 1982 (+) glycosyl transferase
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  • QDG00808.1
 2058 - 3677 (+) drug resistance transporter
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  • QDG00809.1
 4019 - 4951 (+) N,N-dimethyltransferase
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  • QDG00810.1
 5248 - 6177 (+) NDP-hexose aminotransferase
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  • QDG00811.1
 6181 - 6771 (+) NDP-hexose 35-epimerase
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  • QDG00812.1
 6970 - 7851 (+) glucose-1-phosphate thymidylyltransferase
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  • QDG00813.1
 7896 - 8864 (+) dTDP-glucose 46-dehydratase
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  • QDG00814.1
 8861 - 10165 (+) NDP-hexose 34-dehydratase
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  • QDG00815.1
 10162 - 11544 (+) NDP-hexose 23-dehydratase
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  • QDG00816.1
 11610 - 12503 (+) dNDP-hexose 3-ketoreductase
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  • QDG00817.1
 12562 - 13785 (+) putative methyltransferase
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  • QDG00818.1
 13901 - 14770 (+) putative adenosine kinase
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  • QDG00819.1
 14767 - 15636 (+) methylenetetrahydrofolate reductase
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  • QDG00820.1
 16015 - 17007 (-) thioesterase
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  • QDG00821.1
 17134 - 19470 (-) oxygenase-reductase
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  • QDG00822.1
 19473 - 20429 (-) aromatase/cyclase
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  • QDG00823.1
 20429 - 21211 (-) polyketide ketoreductase
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  • QDG00824.1
 21285 - 21581 (-) acyl carrier protein
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  • QDG00825.1
 21666 - 22883 (-) chain length factor
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  • QDG00826.1
 22880 - 24148 (-) beta-ketoacyl synthase
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  • QDG00827.1
 24186 - 24749 (-) polyketide cyclase
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  • QDG00828.1
 24722 - 26254 (-) FAD-binding protein
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  • QDG00829.1
 26678 - 27484 (-) two-component system response regulator
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  • QDG00830.1
 28597 - 29577 (-) quinone oxidoreductase protein
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  • QDG00831.1
 29630 - 30208 (-) hypothetical protein
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  • QDG00832.1
 30532 - 31230 (+) hypothetical protein
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  • QDG00833.1
 31542 - 32075 (-) hypothetical protein
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  • QDG00834.1
 32375 - 33361 (-) two-component system response regulator
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  • QDG00835.1
 33491 - 34300 (+) tetr family transcriptional regulator
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Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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