LOCUS       BGC0002031              5918 bp    DNA     linear   BCT 07-OCT-2016
DEFINITION  Kitasatospora setae KM-6054 DNA, complete genome.
ACCESSION   BGC0002031
VERSION     BGC0002031
KEYWORDS    .
SOURCE      Kitasatospora setae KM-6054
  ORGANISM  Kitasatospora setae KM-6054
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Kitasatospora.
COMMENT     'Otoguro, M. is at NITE Biological Resource Center (NBRC). Ikeda,
            H., Miura, H. and Takahashi Y. are at Kitasato Institute for Life
            Science. Ishikawa, J. is at National Institute of Infectious
            Diseases. Horinouchi, S., Ohnishi, Y. and Kuzuyama, T. are at The
            University of Tokyo. Hayakawa, M. is at University of Yamanashi.
            Nihira, T. and Kitani, S. are at Osaka University. Arisawa A. is at
            Mercian Corp. Nomoto F. is at Nagase & Co. Ltd. The other authors
            are at NITE Genome Analysis Center (NGAC).
            Please visit our web site. URL:http://www.bio.nite.go.jp/
            DOGAN ; Database of Genomes Analyzed at NITE. The database contains
            genome sequence data, physical maps and the genomic and proteomic
            data of the microorganisms analyzed.
            URL:http://www.bio.nite.go.jp/dogan/Top
            The microbial strain and microbial genomic DNA clones used for the
            sequencing project are available through the NBRC.
            URL:http://www.nbrc.nite.go.jp/e/index.html.
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 06:07:43
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..5918
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002031"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..5918
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(4..1182)
                     /locus_tag="KSE_70630"
     CDS             complement(4..1182)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 261.8; E-value: 1.7e-79)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="KSE_70630"
                     /product="putative cytochrome P450"
                     /protein_id="BAJ32821.1"
                     /transl_table=11
                     /translation="MTSTPAKPTRELLFPDLSDDIDARIAWFQHMQKNQPLRFRPEYNL
                     WEVFRYEDVQYVLKNPEEFSVSNKTHLGLPFSFGRADIPDHRFLRGFVARSFQPGNIEG
                     LAPEFAAMVDALLAPARESGRLEVLGELGYPIMERVVGQMFGLRIPGVNLFREWSDQMF
                     GQLIGVRSPDHADVVDLFREQLDERKLDPRDDLMSALLAARRKDDRLAEEKIIHMCLDL
                     ATAGNAPLSLLLAYTFQRFCRDPELFQTLRRDPSLIPGAIEEILRFDFSWFNLWRTARH
                     DTVLGGQEIKADQYVVVWDSSANFDEKHFPQADRFDIRRSPNPHLTFGQGMYICLGLPL
                     VRVLGRVVLERLVATFSDLAADPDRPVRTLEQMKDYVVSLDVVLTPSKTAVS"
     gene            complement(1231..2184)
                     /locus_tag="KSE_70640"
     CDS             complement(1231..2184)
                     /codon_start=1
                     /locus_tag="KSE_70640"
                     /product="hypothetical protein"
                     /protein_id="BAJ32822.1"
                     /transl_table=11
                     /translation="MSALPELRELIASFVSEEPPEIRRIRTGTVPDLPGSYGQYFTAWD
                     FSNSIVRDYAMNLYQLTRLATDESVSVENLLTVFRTLDPIYSTFLGYNGFPVLAEYAQR
                     VGQPAESRAELLDRLTTFTEYVNRLTAWSHHYFPWDLGGERYRYAAEEVAAQAAEAAAA
                     SPSVDSVDSLGDPSQRIPVRLTWQPLGVQVDAEIYADLNPQLATDVLKALPFTVLQDHA
                     VVSGESMYAWAPLVSVAPTPVRERICDAPVGRLRFSQATGNKVIVQYGPTTETLSSPVL
                     GKVVDSHADRLAEVGKAVWESTFSSKEPVWLTVERL"
     gene            complement(2259..3392)
                     /locus_tag="KSE_70650"
     CDS             complement(2259..3392)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103:FAD dependent oxidoreductase (Score: 134.4;
                     E-value: 1e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="KSE_70650"
                     /product="putative oxidoreductase"
                     /protein_id="BAJ32823.1"
                     /transl_table=11
                     /translation="MEGTVKTVGIVGAGVIGACLAFSLAQRGMRVHCVERAEPGGLTTD
                     VSFARLSAVQQPTYPRFELSHTGMIEHARFAEQFYSAPWWHPTESLAWDDEEGGAGPSF
                     ADVVRRLDSWGYRTAWSDAARVNRDREPGVAFPDPGTPVVRFPDEAWVDGPKLVSEMLA
                     AAGATGRLTLWNGAVDAVEVRGGEVRALRLEAGDRIEVDAVVNAAGPGTPAVAATLGTA
                     PLEGFATRSSLVIDLVTDGDPVRHVLRGAQAHVRSAGPGRVRVRSDQVDARLPDGLRSD
                     PDDALVKDLLERAYRTVPALESAAVERVRVGTAVFPADGFPSLGALSAVSGYYEAFANS
                     GITLAPFIGRTLTTRIATGETHPMWAHCSPDRLRAAR"
     gene            3901..5337
                     /gene="pabB1"
                     /locus_tag="KSE_70660"
     CDS             3901..5337
                     /EC_number="2.6.1.85"
                     /codon_start=1
                     /gene="pabB1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 318.6; E-value:
                     1.5e-96)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="KSE_70660"
                     /product="putative p-aminobenzoate synthase"
                     /protein_id="BAJ32824.1"
                     /transl_table=11
                     /translation="MTELLDVTVTAISVETTARALEVRAELCRILGPEEVFLLDDLHPD
                     RSHAGTGTVVGFGRLAEISVTGDRVTVRGSGPVADLLRARCGRTTTDPWAMLRRVTALF
                     RVHTDVRGFSFGFLTTVGYDAAAYMEELPPRQVEPDVPDLTLTLFQDTLWFGRQDGPPV
                     LLRASGPGLPEPLPLGLLRGIPDADLPVPDAPAPLEVRDTVDRETFLGWVERCLDRIRV
                     GDIYQIQVGHRIDVRSALTPEEVYRRLSARNPSPYMYLLTQSGTTLVGASPELLFRLDD
                     GLITMRPIAGTTRRDPTGADNARRVAELRADVKERAEHVMLVDLSRNDVGRVCRPGTLA
                     VTDLMKVEEFSHVFHLVSTVTGTLDAGRDVWDVLCATFPAGTMTGAPKLRAMEIIDEIE
                     IERRGLYAGAVGLVDVRGWAEFALCIRTVTHREPSPGDHRYATQSCAGVVALSEPKREW
                     DETLAKMGAAHWALTGKELA"
     misc_feature    3910..3912
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5340..5918
                     /gene="pabA"
                     /locus_tag="KSE_70670"
     CDS             5340..5918
                     /EC_number="2.6.1.85"
                     /codon_start=1
                     /gene="pabA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249:carbamoyl phosphate synthase small subunit
                     (Score: 135.8; E-value: 2.8e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="KSE_70670"
                     /product="putative p-aminobenzoate synthase glutamine
                     amidotransferase"
                     /protein_id="BAJ32825.1"
                     /transl_table=11
                     /translation="MLVVDALDSFVHIIDQYLRELGAETEVVRSGTRTARELSGWRPDA
                     VVLGPGPGHPADSGHVELVRHFAGDVPLLGVCLGHQAIALAFGGQVRLADHLMHGRTSE
                     IDHDGLGVFAGLPARHTVTRYHSIVVADPLPAELVCTARSTDDGYPMGLRHRDLPVEGV
                     QFHPESITTGAGLTMLENFLAGVRTPVAR"
ORIGIN
        1 gggtcaggag acggcggtct tcgacggcgt caggacgacg tcgagggaga cgacgtagtc
       61 cttcatctgc tccagcgtcc gcaccggccg gtccgggtcg gcggcgaggt cggagaacgt
      121 ggcgaccagg cgctccagga cgacccgccc cagcacgcgc accaggggca ggccgaggca
      181 gatgtacatg ccctgcccga aggtcaggtg ggggttgggc gagcgcctga tgtcgaaccg
      241 gtcggcctgg gggaagtgct tctcgtcgaa gttggccgac gagtcccaga ccaccacgta
      301 ctggtcggcc ttgatctcct gaccgcccag gacggtgtcg tgccgggccg tgcgccagag
      361 gttgaaccac gagaagtcga accgcaggat ctcctcgatg gccccgggga tcagggaggg
      421 gtcgcggcgc agggtctgga agagctccgg gtcccggcag aagcgctgga aggtgtaggc
      481 cagcagcagg gagaggggcg cgttgccggc cgtcgccagg tcgaggcaca tgtggatgat
      541 cttttcctcg gcgagccggt cgtccttgcg ccgggccgcg agcagcgcgc tcatgaggtc
      601 gtcgcgcggg tcgagcttcc gttcgtcgag ctgctcccgg aacaggtcga ccacgtcggc
      661 gtggtcaggg gagcggactc cgatgagctg gccgaacatc tggtcggacc actcccggaa
      721 gaggttcacg ccggggatcc gcaggccgaa catctgcccg acgacgcgct ccatgatcgg
      781 gtagccgagc tcgccgagca cctccagccg gccggattcc cgggcgggcg cgaggagcgc
      841 gtcgaccatg gccgcgaact ccggcgccag gccctcgatg ttgccgggct ggaacgaccg
      901 ggccacgaac ccccgcagga agcggtggtc cggtatgtcg gcccggccga aggagaacgg
      961 caggcccagg tgggtcttgt tggacaccga gaactcttcg gggttcttga gcacgtactg
     1021 cacgtcctcg taccggaaga cctcccacag gttgtattcc gggcggaacc gcaggggctg
     1081 gttcttctgc atgtgctgga accaggcgat ccgcgcgtcg atgtcgtcgc tcaggtcggg
     1141 gaacaggagc tccctggtcg gtttcgctgg cgtactcgtc attccttcac cctttctggc
     1201 cggccgtgcg ttccgtcggt ccgaccgtcg tcagaggcgt tccaccgtga gccagacggg
     1261 ctccttggaa ctgaacgtgc tctcccacac ggccttgccg acctcggcga gccggtccgc
     1321 gtggctgtcg accaccttgc cgaggacggg actgctgagc gtctccgtgg tcggcccgta
     1381 ctggacgatg accttgttgc cggtcgcctg gctgaacctc agccggccga ccggcgcgtc
     1441 gcagatccgc tcgcgcaccg gcgtcggcgc cacgctcacc aggggggccc aggcgtacat
     1501 ggactcgccg ctgaccaccg cgtggtcctg cagcaccgtg aacggcaggg ccttgaggac
     1561 gtccgtggcg agctgcgggt tgaggtcggc gtagatctcg gcgtcgacct gcaccccgag
     1621 cggctgccag gtgagccgga ccgggatccg ctgggacggg tccccgaggg agtccaccga
     1681 gtccaccgag ggggaggccg ccgcggcctc cgcggcctgc gccgccacct cctcggcggc
     1741 gtagcggtag cgctcgccgc ccaggtccca cgggaagtag tggtgcgacc aggcggtgag
     1801 ccggttgacg tactcggtga acgtggtcag ccggtccagc agctcggcgc ggctctccgc
     1861 gggctgcccg acccgctggg cgtactccgc caggaccggg aacccgttgt agccgaggaa
     1921 ggtgctgtag atcgggtcca gcgtgcggaa gaccgtcagc aggttctcca cggagacgct
     1981 ctcgtcggtc gccagcctcg tcagctggta gaggttcatc gcgtagtcgc ggacgatgct
     2041 gttcgagaag tcccaggcgg tgaagtactg gccgtacgac ccgggcagat cgggaacggt
     2101 tcccgtgcgt atccgccgga tctccggcgg ctcctcggag acgaagctcg cgatcagctc
     2161 gcggagttct ggaagtgcgg acatgtttcc cctcctcttg ggccgcggcg ctgccgcggt
     2221 tcgacggctc cggatcgact cggcggtgcc gggggcgctc agcgcgccgc ccgcagccgg
     2281 tcgggggagc agtgggccca catcggatgg gtctccccgg tggcgatgcg ggtggtcagg
     2341 gtccgcccga tgaacggggc gagggtgatg ccgctgttgg cgaaggcctc gtagtagccg
     2401 gagacggcgg acagcgcgcc gaggctgggg aagccgtccg cggggaacac ggcggtaccg
     2461 acgcgcaccc gctccaccgc ggccgactcg agcgcgggaa ccgtgcggta cgcgcgctcc
     2521 agcaggtcct tgacgagcgc gtcgtcgggg tcggagcgca gcccgtccgg cagccgggcg
     2581 tcgacctggt cggagcgcac ccgcacccgc cccggccccg ccgaccggac gtgggcctgc
     2641 gcgccgcgca gcacgtgccg caccggatcg ccgtcggtga ccaggtcgat caccaggctg
     2701 ctgcgcgtcg cgaagccttc gaggggggcg gtgccgagcg tcgcggccac cgcgggcgtc
     2761 cccgggccgg cggcgttgac cacggcgtcg acctcgatgc ggtcacccgc ctccaggcgc
     2821 agcgcccgca cctcgccgcc gcggacctcg acggcgtcga ccgcgccgtt ccacagcgtc
     2881 agccgcccgg tggccccggc ggccgccagc atctcggaga ccagcttcgg cccgtcgacc
     2941 caggcctcgt ccgggaaccg gacgaccggt gtcccggggt ccgggaaggc gacccccggc
     3001 tcccggtcgc ggttcacccg ggccgcgtcg gaccatgccg tccggtagcc ccaggagtcg
     3061 aggcggcgga ccacgtccgc gaaggacggg ccggcgccgc cctcctcgtc gtcccaggcg
     3121 aggctctcgg tgggatgcca ccagggggcc gagtagaact gctcggcgaa ccgggcgtgt
     3181 tcgatcattc cggtgtggct cagttcgaac ctcgggtacg tcggctgctg gaccgcgctc
     3241 agccgcgcga agctgacgtc ggtggtcagg ccgccgggtt cggcccgttc cacgcagtgc
     3301 acccgcatcc cgcgctgggc aagactgaaa gcgaggcagg cgccgatgac gcccgctccc
     3361 acgatcccta cggttttcac tgtcccctcc atgtctcggg gtctcggggc cccggtgtct
     3421 cgggcggacg cggccgccgg ggcgcgtccg gtacgtgccg ggcgctcccc ggcggccgtc
     3481 cggtcacagc aggccggcga tgccgaaggc cgggtcgagc gaccggtcgc ggtcgagccg
     3541 cggaccgcag ggtcgcgggc cgtgcgcgcg cccgtcctgg tgatgaaggt cagccggggg
     3601 cgtccgacgg ccgggccggc acgtccgcca gggcggcgcg gtccggccgg accggctgat
     3661 gctccgccgg agcgtcgcgc caggagacga gcaggtcgga aatcgtcatg aatgcaggcc
     3721 aacacggtcc ccgtccgggg cgcaatgaat tccttgattg gtccggctga cagccggacc
     3781 aatggtctgg ccaaccgtca cctgggcgat ggcatagttt ccgaacgacg ggccggcggc
     3841 cgggcttttt cggcctttgt ctacttttgc tgccaactat ggaggtgcgt catctccgtg
     3901 atgacggaat tactcgacgt caccgtgacc gcgatttccg tggagacgac cgcgagagcg
     3961 ctggaagttc gtgccgaatt gtgtcggatc ctcggcccgg aggaggtctt cctgctcgac
     4021 gacctgcacc cggaccggtc ccacgcgggc accggcaccg tggtgggctt cggccggctc
     4081 gccgagatct cggtgaccgg ggaccgggtc accgtgcgcg gcagcggccc ggtcgccgac
     4141 ctgctgcggg cccgctgcgg ccggacgacg accgacccct gggccatgct ccgccgggtc
     4201 acggccctgt tccgggtgca caccgacgtc cgcggattct ccttcggctt cctcaccacg
     4261 gtcggctacg acgcggccgc gtacatggag gagctgccgc cgcggcaggt cgaacccgac
     4321 gtgccggacc tgaccctgac cctcttccag gacaccctgt ggttcggccg ccaggacggc
     4381 ccgccggtgc tgctccgcgc cagcggcccc ggactgcccg agccgctgcc gctcgggctg
     4441 ctgcgcggca tccccgacgc cgacctcccg gtgccggacg cccccgcccc gctggaggtg
     4501 cgcgacaccg tcgaccggga gacgttcctg ggctgggtcg aacgctgcct ggaccgcatc
     4561 cgggtcgggg acatctacca gatccaggtc ggccaccgga tcgacgtccg cagcgcactg
     4621 acgccggagg aggtgtaccg gcgcctgagc gcccgcaacc cgtcgccgta catgtacctg
     4681 ctcacccagt ccggcacgac gctcgtcggc gcgagcccgg aactgctgtt ccggctggac
     4741 gacggcctga tcaccatgcg gccgatcgcc gggacgacgc gccgcgaccc gaccggcgcc
     4801 gacaacgcgc ggcgggtcgc cgagctgagg gccgacgtca aggaacgggc ggagcacgtg
     4861 atgctcgtcg acctgagccg caacgacgtc ggccgggtct gccggcccgg caccctcgcg
     4921 gtgaccgacc tgatgaaggt cgaggagttc tcccacgtgt tccacctggt gtccaccgtg
     4981 accggcaccc tggacgcggg ccgggacgtc tgggacgtgc tgtgcgcgac gttccccgcc
     5041 ggcaccatga cgggggcgcc gaagctgcgc gcgatggaga tcatcgacga gatcgagatc
     5101 gagcgccgcg gcctctacgc gggcgccgtc ggcctggtgg acgtccgggg gtgggccgag
     5161 ttcgccctct gcatccggac cgtcacgcac cgcgagccct ccccggggga ccaccggtac
     5221 gccacccaga gctgcgcggg agtggtcgcc ctgtccgagc cgaagcggga gtgggacgag
     5281 accctggcca agatgggggc cgcccactgg gcgctcaccg ggaaggagct ggcatgagag
     5341 tgctggtggt ggacgcgctg gacagcttcg tccacatcat cgaccagtac ctgcgcgaac
     5401 tcggggcgga gaccgaggtg gtccgctccg gtacgcgcac cgcgcgggaa ctgtccgggt
     5461 ggcggccgga cgccgtggtc ctggggcccg ggcccggcca ccccgccgac tccggccacg
     5521 tggagctggt ccggcacttc gccggcgacg tcccgctgct cggcgtgtgc ctcgggcacc
     5581 aggccatcgc gctggccttc ggcggccagg tgcgactcgc ggaccacctc atgcacgggc
     5641 gcaccagcga gatcgaccac gacggcctgg gcgtgttcgc gggcctgccg gcccggcaca
     5701 cggtcacccg ctaccactcg atcgtcgtgg ccgatccgct gccggccgag ctcgtctgca
     5761 cggcgcggtc caccgacgac ggctacccga tgggcctgcg ccaccgcgac cttccggtcg
     5821 agggcgtgca gttccacccg gagagcatca ccaccggcgc cggcctcacg atgctggaga
     5881 acttcctggc cggcgtcagg accccggtcg cccggtga
//
