BGC0002032: pentamycin biosynthetic gene cluster from Streptomyces sp. S816
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Location: 152,300 - 233,940 nt. (total: 81,641 nt).
This entry is originally from NCBI GenBank QQVZ01000001.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002032
Short description pentamycin biosynthetic gene cluster from Streptomyces sp. S816
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
QQVZ01000001.1
152300 - 233940
via
Compounds
  • pentamycin
Species Streptomyces sp. S816 [taxonomy]
References
Chemical products information
pentamycin Evidence:
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C35H58O12
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • DV517_01290
  • TGZ15156.1
  • rifR
 152303 - 153070 (-) oleoyl-ACP hydrolase
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    • DV517_01300
    • TGZ15157.1
    		 153188 - 154831 (-) cholesterol oxidase
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      • DV517_01310
      • TGZ15158.1
      		 155034 - 155612 (-) hypothetical protein
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        • DV517_01320
        • TGZ15159.1
        		 156014 - 159580 (+) hypothetical protein
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          • DV517_01330
          • TGZ15160.1
          		 159602 - 159844 (-) ferredoxin
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            • DV517_01340
            • TGZ15161.1
            		 159841 - 161055 (-) cytochrome P450
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              • DV517_01350
              • TGZ15162.1
              		 161126 - 162325 (-) cytochrome P450
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                • DV517_01360
                • TGZ15163.1
                • adhP
                		 162370 - 163626 (-) crotonyl-CoA carboxylase/reductase
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                  • DV517_01370
                  • TGZ15164.1
                  		 163685 - 173746 (-) hypothetical protein
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                    • DV517_01380
                    • TGZ15165.1
                    		 173793 - 192254 (-) hypothetical protein
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                      • DV517_01390
                      • TGZ15166.1
                      		 192290 - 197761 (-) hypothetical protein
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                        • DV517_01400
                        • TGZ15167.1
                        • rifE
                        		 197794 - 208635 (-) polyketide synthase
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                          • DV517_01410
                          • TGZ15168.1
                          		 208707 - 232229 (-) hypothetical protein
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                            • DV517_01420
                            • TGZ15169.1
                            		 232514 - 233731 (+) cytochrome P450
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                              • DV517_01430
                              • TGZ15170.1
                              • fer
                              		 233743 - 233937 (+) ferredoxin
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                                Biosynthesis information
                                Annotation changelog

                                Entry version: 3

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-10-07
                                Update chemical activity to schema version 2.11
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 2

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-09-15
                                Cleaned up synonym list
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2022-09-15
                                Fetch compound properties from PubChem
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2022-09-15
                                Updated bioactivity data
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 1

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2019-10-16
                                Submitted
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                Detailed domain annotation
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