BGC0002032: pentamycin biosynthetic gene cluster from Streptomyces sp. S816
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Location: 152,300 - 233,940 nt. (total: 81,641 nt).
This entry is originally from NCBI GenBank QQVZ01000001.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0002032
Short description pentamycin biosynthetic gene cluster from Streptomyces sp. S816
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: QQVZ01000001.1
Compounds
  • pentamycin
Species Streptomyces sp. S816 [taxonomy]
References
Chemical products information
pentamycin [synonyms: Fungichromin, Cogomycin, Lagosin, Cantricin, Moldcidin B]
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C35H58O12
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • DV517_01290
  • TGZ15156.1
  • rifR
 152303 - 153070 (-) oleoyl-ACP hydrolase
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  • DV517_01300
  • TGZ15157.1
 153188 - 154831 (-) cholesterol oxidase
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  • DV517_01310
  • TGZ15158.1
 155034 - 155612 (-) hypothetical protein
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  • DV517_01320
  • TGZ15159.1
 156014 - 159580 (+) hypothetical protein
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  • DV517_01330
  • TGZ15160.1
 159602 - 159844 (-) ferredoxin
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  • DV517_01340
  • TGZ15161.1
 159841 - 161055 (-) cytochrome P450
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  • DV517_01350
  • TGZ15162.1
 161126 - 162325 (-) cytochrome P450
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  • DV517_01360
  • TGZ15163.1
  • adhP
 162370 - 163626 (-) crotonyl-CoA carboxylase/reductase
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  • DV517_01370
  • TGZ15164.1
 163685 - 173746 (-) hypothetical protein
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  • DV517_01380
  • TGZ15165.1
 173793 - 192254 (-) hypothetical protein
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  • DV517_01390
  • TGZ15166.1
 192290 - 197761 (-) hypothetical protein
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  • DV517_01400
  • TGZ15167.1
  • rifE
 197794 - 208635 (-) polyketide synthase
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  • DV517_01410
  • TGZ15168.1
 208707 - 232229 (-) hypothetical protein
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  • DV517_01420
  • TGZ15169.1
 232514 - 233731 (+) cytochrome P450
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  • DV517_01430
  • TGZ15170.1
  • fer
 233743 - 233937 (+) ferredoxin
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Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Cleaned up synonym list
  • Fetch compound properties from PubChem
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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