LOCUS       BGC0002034             19389 bp    DNA     linear   BCT 20-AUG-2019
DEFINITION  Streptomyces sp. IB2014 016-6 contig00041, whole genome shotgun
            sequence.
ACCESSION   BGC0002034
VERSION     BGC0002034
KEYWORDS    .
SOURCE      Streptomyces sp. IB2014 016-6
  ORGANISM  Streptomyces sp. IB2014 016-6
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     Bacteria and source DNA available from Russian Collection of
            Agricultural Microorganisms (RCAM), St. Petersburg, Russia.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 16:45:26
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 86568
            Orig. end    :: 105957
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1173
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009480348.1"
                     /locus_tag="EW053_28335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="epoxide hydrolase"
                     /protein_id="TXL86004.1"
                     /sec_met_domain="PF00561 (E-value: 2.8e-18, bitscore: 56.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.6e-10, bitscore:
                     31.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPTSDVQAFETHATDADLDDLRARLAAARLPEAETVRGAAPGP
                     RRWEQGVPLADLVDVVNYWRTEYDWRSFEARLNRIGQFRTTIDDLGIHFLHRRSARADA
                     TPVILTHGWPGSIAEFTDVVDELADPKDADAPAFHVVVPSLPGFGHSDKPATTGWGTEK
                     IAAAWVELMGRLGYDKFAAHGGDWGGVITTVLGGRFPAHVLGIHSTLAQAPPGLTTDGL
                     TAVEREWTDQTRDFWRHRAAYAKQQATRPQTIGYSLVDSPVGLLAWILDKFAEWSDTED
                     SPFELISRDRVLDDVTLYWLTRTGASAARIYYESHDSLDPELRVDVPSAISMYPRDIEK
                     CPRPWAQERYRRIVRWREPGIGGHFPSLEVPGDFVGDLREGLAAVLAANR"
     subregion       1..19389
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19389
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..1173
                     /locus_tag="EW053_28335"
     gene            complement(1280..4465)
                     /locus_tag="EW053_28340"
     CDS             complement(1280..4465)
                     /codon_start=1
                     /inference="COORDINATES: protein
                     motif:HMM:PF01979.18,HMM:PF07676.10"
                     /locus_tag="EW053_28340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidohydrolase"
                     /protein_id="TXL86005.1"
                     /transl_table=11
                     /translation="MSLLKKHENLMDVTNPDPAPAPGPSRRHVLAVSGAVTAGALTAGG
                     TSAGRAAAAGTEPGRPAERPGGAPRTATVTVSEGTNMAAALSPDGTGLAIDVLSAVWVV
                     PGAGGAAVRLTGELQDATQPHWAPDGSRVVFQSFRDGAYQLWSVKRDGTGLTRLTDDDY
                     DNREPQYAPDGSRIVFTSDRSGSNDLWLLDPAAGVRTQLTTGPDEDGTPAWSADGRTIV
                     CTVNDAAIDSVDVATGTRTRLITASAGAKIFGPAPSPDGRRVSYVQFTGTRADVMIDGQ
                     VAAAGEDVHALRTSWTSDGDLLYTAGGRVRRLRPGGTPRTVDFTATVTFTRKPWTPRVR
                     DFTSRAAQQARGIASPVVSRDGQRVAFRALNALWVMKTGEAPVRLADDGFFNSDPDWSP
                     DGTALVHASDRSGTAALWRRDLTGGEPVRLTSLPGAQLTPRWSPDGTKIAYQDENGATW
                     VLELASGAVRQVLPVLFQPGRPTWSPDGAHLAVAANQPYSRRNRAGLSEVLTVDLATGA
                     TRSQPVAAHRSIATRGDDGPVWTPDGKHFVFVMESTAWRVPVDPTGRITGAPEQITTEV
                     TDSLSVDTNGRLFYLSNGTLRTVPLTGGTPRTVPVPLTYRRPATARTVVLRAGAVWDGR
                     AEQLRGAADIVVKGDRIAAVRPAGQGRGDTVVDLSGLTAMPGLVDAHLHWHLRGRQWGD
                     RTGRLLLSYGITTVLSPGDPAYQMVETREAIESGAQVGPRFFGTGDALDGARVFWNFAR
                     PVVGTDQLRLEMERAERLSYDLVKTYIRLQAPLERAVTRQAHERGLLVTSHYAYPHAAY
                     GMDAMEHTGGGNRVGYSQTQTRLGRAYEDAIAVLTAAGMPVTSTLMNSSVLLADDRSLV
                     TDERTRLLYPPWDYTVLVAKADAADGPDAGLNRALLAGGVDMLLRVQRGGGSVIAGSDA
                     PLDDPALSLHQNLRAMVRGGFTPYEALRTATANPVRRMGVDNDLGTLEAGMLADLVFVE
                     GDPLRDIDAAAAVRTVVTGGTVRTVSSLLEPFRATGTRSPAANLKERSLVSARTERRYG
                     WQDPRPGGTGCLC"
     gene            complement(4470..5720)
                     /locus_tag="EW053_28345"
     CDS             complement(4470..5720)
                     /NRPS_PKS="Domain: Aminotran_1_2 (80-406). E-value:
                     1.5e-26. Score: 85.2. Matches aSDomain:
                     nrpspksdomains_EW053_28345_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 292.9; E-value: 6e-89)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460121.1"
                     /locus_tag="EW053_28345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="TXL86119.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.9e-27, bitscore:
                     85.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSINFLNEVMGRFPDALSFAPGAPHISFFDQIDIPRHIDRYLRH
                     LTEDRGLKPDLAERLLYQYGPSRGLIGDLVAGALRTDQGIDVPPESVVITVGCQEAMLL
                     ALRALAAEPTDLVAVVNPCFVGLSGAAGLLGVDLVPVDDTDDGIDFAQLDDVCRAAREA
                     GRRIRALYVAPDFSNPSGGFLSLADRHRLLDVAAREDFLLLEDNAYAFTAHQPGALPPL
                     KALPGGERVVHLGTFAKVCMPGARVGYVVADQRVRDASGRTGLLADELATLKSMVTVNT
                     SPIAQAVVGGILLEHRGSLASVVSAKAALYQRNLRLLLDALDHALGPGTGAPAGVSWNR
                     PRGGFFVRVRLPVPADERLLERSAREFGVLWTPMSHFYLGSGGDYQLRLACSYLDPDAI
                     KEGVARLARFLRAVCPS"
     aSDomain        complement(4503..5480)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EW053_28345_Aminotran_1_2.1"
                     /evalue="1.50E-26"
                     /label="EW053_28345_Aminotran_1_2.1"
                     /locus_tag="EW053_28345"
                     /protein_end="406"
                     /protein_start="80"
                     /score="85.2"
                     /tool="antismash"
                     /translation="TDQGIDVPPESVVITVGCQEAMLLALRALAAEPTDLVAVVNPCFV
                     GLSGAAGLLGVDLVPVDDTDDGIDFAQLDDVCRAAREAGRRIRALYVAPDFSNPSGGFL
                     SLADRHRLLDVAAREDFLLLEDNAYAFTAHQPGALPPLKALPGGERVVHLGTFAKVCMP
                     GARVGYVVADQRVRDASGRTGLLADELATLKSMVTVNTSPIAQAVVGGILLEHRGSLAS
                     VVSAKAALYQRNLRLLLDALDHALGPGTGAPAGVSWNRPRGGFFVRVRLPVPADERLLE
                     RSAREFGVLWTPMSHFYLGSGGDYQLRLACSYLDPDAIKEGVARL"
     gene            complement(5783..7162)
                     /locus_tag="EW053_28350"
     CDS             complement(5783..7162)
                     /NRPS_PKS="Domain: ECH (268-391). E-value: 4e-18. Score:
                     57.4. Matches aSDomain: nrpspksdomains_EW053_28350_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 84; E-value:
                     1.5e-25)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006236895.1"
                     /locus_tag="EW053_28350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="TXL86120.1"
                     /transl_table=11
                     /translation="MSAAGLALAAEIRDREAPLAALPPRSDRSEEQQLGAAAIHRACRE
                     LRAAFLRAHAAAVYDRLTEGRSARLGLTELAGAAAESFPGLVPDAAQLAEELRHAQADK
                     EGREIDQGIFFREILRLPGAGAHLVDVMRDPTPRAHALLPDFRATGRAELGKVTVERHG
                     DGGHVTFHNDSCLNAEDNDLIAQLEVAVDLVLLDDGIRVGVLRGGPMTHPRYRGRRVFS
                     AGVNLADLHHGRISFTGFLLQRELGYISKMYRGLSTLGRPDTYPAHGVEKPWVAAVETF
                     AIGGGTQLLLVMDKVIAAADSYLSLPAAQEGIVPGAANFRLARLTGGRVARQAVLGGRK
                     IWAGEPDARLLIDEVVDPKAMDRAVDDAVTQLAAPAVLANRRMLRVSEEPVDAFRAYMA
                     EFSLTQAERLYGEDVLDKVGRFSARSGTGPSATDPPKSGTEPGAAAGTRTDTHAGAETG
                     R"
     aSDomain        complement(5990..6358)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EW053_28350_ECH.1"
                     /evalue="4.00E-18"
                     /label="EW053_28350_ECH.1"
                     /locus_tag="EW053_28350"
                     /protein_end="391"
                     /protein_start="268"
                     /score="57.4"
                     /tool="antismash"
                     /translation="GVEKPWVAAVETFAIGGGTQLLLVMDKVIAAADSYLSLPAAQEGI
                     VPGAANFRLARLTGGRVARQAVLGGRKIWAGEPDARLLIDEVVDPKAMDRAVDDAVTQL
                     AAPAVLANRRMLRVSEEPV"
     gene            complement(7311..8075)
                     /locus_tag="EW053_28355"
     CDS             complement(7311..8075)
                     /NRPS_PKS="Domain: ECH (77-193). E-value: 4.9e-15. Score:
                     47.3. Matches aSDomain: nrpspksdomains_EW053_28355_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 56.3; E-value:
                     4.3e-17)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:PF00378.18"
                     /locus_tag="EW053_28355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="TXL86006.1"
                     /transl_table=11
                     /translation="MSGTDTDTPNAPTVRLHDEAAAVLTVGDEELTPALVDRVRTAAEK
                     AEGADRGVVLLLLGGAGAAEGAPPAGTGIHLVNTWERALRRLETSGRPTLALVEGTCTG
                     PALETLLTADYRIAAGDARLRLPGAEDGAWPSTALHRLAQQIGTARARRLLLRRPWLDG
                     EQAADLDLVDETADGGEAALRRAVLVAGELSAVPGREWSIRRRLLFDATLSYEEALGAH
                     LAACDRSLRRRTTAGQSAAEQAPADGSLAQAR"
     aSDomain        complement(7497..7844)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EW053_28355_ECH.1"
                     /evalue="4.90E-15"
                     /label="EW053_28355_ECH.1"
                     /locus_tag="EW053_28355"
                     /protein_end="193"
                     /protein_start="77"
                     /score="47.3"
                     /tool="antismash"
                     /translation="NTWERALRRLETSGRPTLALVEGTCTGPALETLLTADYRIAAGDA
                     RLRLPGAEDGAWPSTALHRLAQQIGTARARRLLLRRPWLDGEQAADLDLVDETADGGEA
                     ALRRAVLVAGEL"
     gene            complement(8194..9399)
                     /locus_tag="EW053_28360"
     CDS             complement(8194..9399)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:chalcone and stilbene synthase domain protein
                     (Score: 325.5; E-value: 5.3e-99)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006351027.1"
                     /locus_tag="EW053_28360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type III polyketide synthase"
                     /protein_id="TXL86007.1"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 4.3e-22,
                     bitscore: 68.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATAPTAPASSSAVPTEPATRAPGQRLSTANAGPRPSVVGFGTA
                     TPANSYTQREMLELFGIEDPRIRSVFLNSAIERRYLTLPPELADGTRKTETQGELLAKH
                     KEQGVRTGREALETALKRAGLALSDVGYLCCVTTTGLLTPGFSAHLVKEAGLPVSTGRL
                     DVVGMGCNAGLNAMAAVASWSAANPGQAAVMVCAEVCSAAYVFDGTMRTSVVNSLFGDG
                     AAAVVMVTDPAGTARAAHGAHATETAEADEAAPVGTVLKAASRIIPEAVDAMRYDWDDD
                     QGKFSFFLDRDVPYVVGANAEEVVDRLLGGTGLERADIDHWLVHSGGKKVIDSVKVNLG
                     LSTYALRHTTGVLRDYGNLSSGSFLFSYERLMEEGRVRRGDYGVLMTMGPGSTIETALV
                     QW"
     gene            complement(9396..10640)
                     /locus_tag="EW053_28365"
     CDS             complement(9396..10640)
                     /NRPS_PKS="Domain: Aminotran_1_2 (167-407). E-value:
                     1.2e-16. Score: 52.6. Matches aSDomain:
                     nrpspksdomains_EW053_28365_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109:8-amino-7-oxononanoate synthase (Score: 190.6;
                     E-value: 6.2e-58)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005143568.1"
                     /locus_tag="EW053_28365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="TXL86008.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3e-17, bitscore:
                     52.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRTIERHNWVATRVDKTSDALTRAIATDLTSHVFTGREGKEVTL
                     ADGRSAVEFISCSYLGLDTHPALVEAAVASLRRVGVQFSSSRTRMRYEDLESLERMLGV
                     VYGGRHATCFTAVGSVHLGVLPLLGTGVLPSYPVSASGVTFLIERTAHASIQVLRGVLE
                     QIGDVDRFDCEDLDDLAVRLAAVRDAGRTPIVLVDGVGSMGGLIDVAALYDLCAAAEGY
                     LYVDDAHGVSITGEQGAGFAYEEFRHLPGGLPASVILVGSLAKAFGGSNGGFVLLNTEE
                     DTVELRRFGNPLIFGGPIALPVISACRASAELHLDGTVARLQRDLWRNTELFDSRTGGA
                     LFNAGTRSPIRGALFKSEEDALVAAARLRKAGVIVTPAFFPTVAKGSGLIRMAVSAAHT
                     TEQIELATNELEVPA"
     aSDomain        complement(9420..10139)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EW053_28365_Aminotran_1_2.1"
                     /evalue="1.20E-16"
                     /label="EW053_28365_Aminotran_1_2.1"
                     /locus_tag="EW053_28365"
                     /protein_end="407"
                     /protein_start="167"
                     /score="52.6"
                     /tool="antismash"
                     /translation="VDRFDCEDLDDLAVRLAAVRDAGRTPIVLVDGVGSMGGLIDVAAL
                     YDLCAAAEGYLYVDDAHGVSITGEQGAGFAYEEFRHLPGGLPASVILVGSLAKAFGGSN
                     GGFVLLNTEEDTVELRRFGNPLIFGGPIALPVISACRASAELHLDGTVARLQRDLWRNT
                     ELFDSRTGGALFNAGTRSPIRGALFKSEEDALVAAARLRKAGVIVTPAFFPTVAKGSGL
                     IRMAVSAAHTTEQIELAT"
     gene            complement(10755..12122)
                     /locus_tag="EW053_28370"
     CDS             complement(10755..12122)
                     /NRPS_PKS="Domain: AMP-binding (104-305). E-value: 6.7e-08.
                     Score: 23.3. Matches aSDomain:
                     nrpspksdomains_EW053_28370_AMP-binding.1"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EW053_28370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="phenylacetate--CoA ligase family protein"
                     /protein_id="TXL86009.1"
                     /transl_table=11
                     /translation="MLGEMYPTSHHSEARAGESSKIELAENLDILTRAQLDEMQQRNLA
                     RTVDALKGNPAVAACWPGALDVRVPRDLLKLPLFSPADLQASCPPASENLVLGDGRSGL
                     VLRSSGTSGRRKMIYHSWEFSRRVSALGARGVRSALRPHPRRIANFLYPGELNGAFTFA
                     QEVTELLPAMSFPMGSSALASPETAELLRENRVDAVICSPSAGTGLLTGDATRELLRGV
                     DSLLYIGEILGESRERQLADARPDLRVRSFSYSTSETGPVGYQCTYQSGSTHHLHEDVL
                     VVEVVDTDAERIQPDGRVGEVVVTMLTDSGMPLLRYRIGDEGFIETRPCLCGSAARQLT
                     LTGRVGMSMNVDSTTISRDLVMEQLATLGISDPADCQFQVTQHDPGFSIRLLVSERTPP
                     SVTTEDAVAALHGAYHMGRVFTAPLYRGLTLERVDSSEFHHTARGKTPFFVNRTAG"
     aSDomain        complement(11208..11810)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EW053_28370_AMP-binding.1"
                     /evalue="6.70E-08"
                     /label="EW053_28370_AMP-binding.1"
                     /locus_tag="EW053_28370"
                     /protein_end="305"
                     /protein_start="104"
                     /score="23.3"
                     /tool="antismash"
                     /translation="VLRSSGTSGRRKMIYHSWEFSRRVSALGARGVRSALRPHPRRIAN
                     FLYPGELNGAFTFAQEVTELLPAMSFPMGSSALASPETAELLRENRVDAVICSPSAGTG
                     LLTGDATRELLRGVDSLLYIGEILGESRERQLADARPDLRVRSFSYSTSETGPVGYQCT
                     YQSGSTHHLHEDVLVVEVVDTDAERIQPDGRVGEVVVT"
     gene            complement(12266..13117)
                     /locus_tag="EW053_28375"
     CDS             complement(12266..13117)
                     /NRPS_PKS="Domain: ECH (15-256). E-value: 4e-59. Score:
                     191.7. Matches aSDomain: nrpspksdomains_EW053_28375_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 220.1; E-value:
                     4.4e-67)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_629083.1"
                     /locus_tag="EW053_28375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-CoA hydratase"
                     /protein_id="TXL86010.1"
                     /transl_table=11
                     /translation="MSELRYGEYILVHRTHNGRIAELVLNRPERMNAVSADFGAALADA
                     TADLGHDPSVGVTVITSRCERAFCVGADLKERAGYTEADRAAARPGSRAAYAGVLALPM
                     PVVAAVQGYALGGGYEIALSCDVIVADPGATVGLPETTVGVIPGGGGTQLLPRRVGAAV
                     AAQLIFSGRRVPATEARDLGLVDVLAPAGAVRATALDLARTYAANSPVALRAAKRALRL
                     GQGRDLAAGLEVEDAAWHTVAFSADWAEGVAAFNGRRPPEWPGYGTADRNGNRPAAANV
                     PP"
     aSDomain        complement(12350..13072)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EW053_28375_ECH.1"
                     /evalue="4.00E-59"
                     /label="EW053_28375_ECH.1"
                     /locus_tag="EW053_28375"
                     /protein_end="256"
                     /protein_start="15"
                     /score="191.7"
                     /tool="antismash"
                     /translation="HNGRIAELVLNRPERMNAVSADFGAALADATADLGHDPSVGVTVI
                     TSRCERAFCVGADLKERAGYTEADRAAARPGSRAAYAGVLALPMPVVAAVQGYALGGGY
                     EIALSCDVIVADPGATVGLPETTVGVIPGGGGTQLLPRRVGAAVAAQLIFSGRRVPATE
                     ARDLGLVDVLAPAGAVRATALDLARTYAANSPVALRAAKRALRLGQGRDLAAGLEVEDA
                     AWHTVAFSADWAEGVAAFN"
     gene            13419..14426
                     /locus_tag="EW053_28380"
     CDS             13419..14426
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:PF00196.17"
                     /locus_tag="EW053_28380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR family transcriptional regulator"
                     /protein_id="TXL86011.1"
                     /transl_table=11
                     /translation="MNMPAHHVDRSPLPIDEEITSAYAFLCGSGNASVEQIAAALEIGI
                     ERARQLVGRLTELHLIDSAGDGTYTPGSPRALGAGVIAPAIRELESGQQQIIRMMTELD
                     ALTKIYERSPAERLRRPRIEILPEVTAVRAVLTELSAGARTEILTSQPGGARPADVLRE
                     SLERTEAVLSRGITMRTVYQYTAQFSQVTVDYVRHVTERGVEVRMLGDALMRMIIFDRE
                     IAVLPQYDRDGAVVVSDRSIVDFAVQAFERAWPVARPFPVSYDRGQVKSTSVEIQLSIS
                     RLLVEGLEDKVIARRMGMSLRTCQRHISEIMSRIGARNRMHAGYLLGKLIDSQN"
     gene            complement(14448..15767)
                     /locus_tag="EW053_28385"
     CDS             complement(14448..15767)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 65.1; E-value: 6.9e-20)"
                     /gene_kind="transport"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EW053_28385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="MFS transporter"
                     /protein_id="TXL86012.1"
                     /transl_table=11
                     /translation="MTGTATETGTPKAGWYPRAVGAGLGFTLLSNFGLAMVLTLLPVAV
                     LHGGRIEPSVFSFALSVHVGSALVGALVTPIAFSRVHPAWVLTIASSLKAAGFVTVAVS
                     TSAPALYLFAVLAGLGVGISRPAVRSLLVAAATDDRRSQVFQVFFILLNTAYVLAPLAA
                     GPVGRAGVPALLVLAVVETVIGITVGLLARGLDFALPPRGANGLRGRLTVLRTPAVAVV
                     LGYTFAIYFAMGFLYAMILLYEVVNPAQAEHRTLFLSFQPLAIIAIQLALLPFFTRLRR
                     RALYLIVAVGGGTGLVLSFSGSLTLILAGLTLFAVAECLAFPKIQVEAADTVPQTRLTD
                     VIALVSLVTAIGEICGNMAAGLAVSTSASWLPQPAHFGMGVGVLAGLVLLVGGLAVTRY
                     VVPSGGAKATPEVAPGGSADGSPDGSPDDSPGASSARDRS"
     gene            complement(15764..16762)
                     /locus_tag="EW053_28390"
     CDS             complement(15764..16762)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:PF08443.9"
                     /locus_tag="EW053_28390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="TXL86013.1"
                     /sec_met_domain="RimK (E-value: 7.7e-10, bitscore: 28.5,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPMRSLVGVAIVANERLVTWICHPDDFLPEYVDKITEQMTERWAE
                     PCERHGFAFRFISANELVPACDERPRLWHDGVDLLRTRQAYIVDDVSGDPQATHFLRGI
                     YRAIDASDSVLLNRSLVGPECLERDKLAILARASTLGVRVPKTVALPFGRYARKGLDVV
                     RKEIGEGPYILKAREMGIGFGVLKLDSYEQLRAAVDIASQTGQSYIVQEYLPNKGDLRV
                     AMVDGKFAASMLRSPAEGAYLANITQGGSSSANPDVATVLGDVERIVADLQAGYLCVDW
                     LLTDDGPVLGEWGTAMAEFSSMPEPARSQLADAFFPWVGRLLSEPAPAHSA"
     gene            complement(16915..18348)
                     /locus_tag="EW053_28395"
     CDS             complement(16915..18348)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018551353.1"
                     /locus_tag="EW053_28395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rRNA cytosine-C5-methyltransferase"
                     /protein_id="TXL86014.1"
                     /transl_table=11
                     /translation="MNEQARRRPSKTYRRPKKDPVRILAFEALRAVDERAAYANLVLPP
                     LLKKAREAGDFDNRDAALATELVYGTLRRQGTYDAIISACIDRPLRQVDPPVLDVLALG
                     AHQLLGTRIPTHAAVSASVELARVVLGDGRAKFVNAVLRKISKDGLDAWVERVAPPYDE
                     DAEDHLAVVHSHPRWIVSALWDALGGGRAGIEDLLEADNERPEVTLVARPGRVSADALL
                     DTLGEESGLPGRWSPYAVRLTEGGEPGAIDAVREGRAGVQDEGSQLVAVALANAPLEGT
                     DSRWLDGCAGPGGKAALLAALAAERGARLLASEKQPHRARLVERALAGNPGPYQVITAD
                     GTRPPWRPGVFDRVLVDVPCTGLGALRRRPEARWRRRPEDLEGFAPLQRSLLREALKAV
                     RVGGVVGYATCSPHLAETRVVVEDVLKGRGGPAAEAEWVDARPLMPGVAALGEGPDVQL
                     WPHVHGTDAMYLALLRRTA"
     gene            complement(18433..19389)
                     /locus_tag="EW053_28400"
     CDS             complement(18433..19389)
                     /EC_number="2.1.2.9"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228:methionyl-tRNA formyltransferase (Score: 286.6;
                     E-value: 3.2e-87)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003947011.1"
                     /locus_tag="EW053_28400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="TXL86015.1"
                     /transl_table=11
                     /translation="MKLVFAGTPEVAVPALDALIASDRHEVAAVVTRPDAPAGRGRRLV
                     ASPVAQRAEEEGIEILRPARPRDEAFLTRLREIAPDCCPVVAYGALLPRVALDIPANGW
                     VNLHFSLLPAWRGAAPVQHAVIAGDETTGAATFLIEEGLDSGPVYGVITEDVRPTDTSG
                     DLLTRLAFAGAGLLAATMDGIEDGTLKAVQQPTEGISLAPKLTVEDARVDWAAPALRVD
                     RVVRGCTPAPGAWTVFRGERLKLIQLKPVPDRTDLAPGEPAVGKNSVHVGTGSYAVELL
                     WVQPQGKKPMRAADWARGVRIAPGERLGAAEGAADVR"
ORIGIN
        1 atgccccgtc cgaccagcga cgtgcaagca ttcgaaaccc atgcgaccga cgccgacctc
       61 gacgatctgc gcgcgcggct ggcggcggcg cggctgccgg aggccgagac cgtccgcggc
      121 gcggcgcccg gccctcgccg atgggaacag ggcgtccctc tcgccgacct cgtcgatgtc
      181 gtgaactact ggcgcaccga atacgactgg cggtcgttcg aagcgcgcct caaccggatc
      241 ggccagttcc gcaccaccat cgatgatctg ggaatccact tcctgcaccg ccggtccgcg
      301 cgcgcggacg ccactcctgt gatcctgacg cacggctggc cgggcagcat cgccgagttc
      361 accgatgtgg tggacgagct ggcggatccg aaagacgccg acgcgcccgc gttccacgtc
      421 gtggtgccgt cgctgccggg cttcggacac agcgacaagc cggccaccac cgggtgggga
      481 accgagaaga tcgcggccgc ctgggtggaa ctgatgggaa ggctcggcta cgacaagttc
      541 gcggcccacg gcggcgactg gggaggtgtg atcaccaccg tcctcggcgg caggttcccc
      601 gcgcacgttc tcggcatcca ctcgaccctc gcccaggcac cacccggcct gacgacggac
      661 gggctgacgg cggtcgagcg cgagtggacc gatcagaccc gcgatttctg gcgccatcgt
      721 gccgcgtacg cgaagcagca ggcgacccgg ccgcagacca tcggctactc gctcgtcgac
      781 tcaccggtcg ggcttctcgc ctggatcctc gacaagttcg ccgagtggtc ggacaccgag
      841 gacagcccgt tcgagctgat ttccagggac cgcgttcttg acgacgtcac cctgtactgg
      901 ctgacccgga ccggcgcgtc ggcggcccgt atctactacg agagccacga ctcgctggac
      961 cccgaactcc gggtggacgt gccgtcggcg atcagcatgt atccccgcga catcgagaag
     1021 tgtccgcgcc cctgggcaca ggagcggtac cggcggatcg tccgatggag ggagcccggg
     1081 atcgggggac acttcccgtc gctggaggtc cccggggact tcgtcgggga tctgcgggag
     1141 ggcctcgcgg cggtgctggc cgcgaatcgc tgaacgcggc cgggtggccg gccggtgccg
     1201 ggaccgggac agcgtcccgg tcaccggccg cccggcccgg cccccgccgg tcctccctca
     1261 gcccttcctc agcgcttcct cagcacagac agcccgtccc gccggggcgc ggatcctgcc
     1321 acccgtaccg gcgctcggtc cgcgcggaca ccagggaccg ctccttcaaa ttggccgcgg
     1381 gagaccgcgt acccgtggct ctgaagggct ccagcagcga ggacaccgta cggaccgtgc
     1441 cgcccgtcac caccgtccgt acggccgccg ccgcgtcgat gtcccgcagc ggatcgccct
     1501 ccacgaagac cagatcggcg agcatgcccg cttcgagcgt gccgaggtcg ttgtccacgc
     1561 ccatgcgccg cacggggttg gcggtggcgg tgcgcagcgc ctcgtacggg gtgaagccgc
     1621 cccgcaccat cgcgcgcagg ttctggtgca gcgacagggc gggatcgtcc agcggggcgt
     1681 ccgagcccgc gatgacgctg ccgccgccgc gctgtacgcg cagcagcatg tcgacgccgc
     1741 ccgccagcag cgcgcggttc agcccggcgt ccgggccgtc ggccgcgtcc gccttggcca
     1801 ccaggaccgt gtagtcccac ggcgggtaga gcaggcgggt ccgttcgtcg gtgaccaggg
     1861 aacggtcgtc ggcgagaagc acggaggagt tcatcagtgt ggaggtgacg ggcatcccgg
     1921 cggccgtcag gacagcgatg gcgtcctcgt aggctctgcc cagccgggtc tgggtctgcg
     1981 agtagccgac gcggttgccg ccgcccgtgt gctccatggc gtccatgccg tacgccgcgt
     2041 gcgggtaggc gtagtgcgag gtgacgagca gcccccgctc gtgcgcctgg cgggtgaccg
     2101 cgcgctccag tggggcctgc agccggatgt aggtcttgac gaggtcgtac gagagccgtt
     2161 cggcgcgctc catctccagc cgcagctggt cggtgccgac cacgggacgg gcaaagttcc
     2221 agaacacccg cgccccgtcc agggcgtcgc ccgtaccgaa gaagcgcggc cccacctggg
     2281 cgcccgactc gatggcctcc ctcgtctcca ccatctggta ggccggatcg ccgggtgaca
     2341 gcacggtggt gatgccgtac gacaggagca ggcgccccgt gcggtcgccc cactgcctgc
     2401 cgcgcaggtg ccagtgcaga tgggcgtcga ccagtccggg catcgcggtc aggcccgaca
     2461 ggtccacgac ggtgtcgccc cggccctgtc ccgcggggcg gaccgcggcg atccggtcgc
     2521 ccttgacgac gatgtcggcg gcgccgcgca gttgctcggc gcgcccgtcc cacacggcac
     2581 cggcgcggag caccacggtg cgggccgtcg ccggtctgcg gtaggtgagg gggacgggca
     2641 cggtgcgcgg ggtgccgccg gtgagcggga cggtgcgcag cgtgccgttg ctcagataga
     2701 agagacggcc gttcgtgtcc acggagaggg agtcggtgac ctccgtggtg atctgctcgg
     2761 gtgcgccggt gatccgtccg gtgggatcga cgggcacccg ccacgccgtg ctctccatga
     2821 cgaagacgaa gtgcttgccg tccggggtcc acacgggtcc gtcgtcgccc cgggtggcga
     2881 tcgaccggtg ggcggccacg ggctgggagc gggtggcgcc ggtggccagg tcgacggtga
     2941 ggacttcgct cagcccggcc cgattgcgcc tggagtaggg ctggttggcg gcgaccgcga
     3001 ggtgggcgcc gtccggggac caggtggggc ggcccggctg gaagaggacg ggcagcacct
     3061 ggcgtacggc gccggaggcg agttccagca cccaggtcgc gccgttctcg tcctggtagg
     3121 cgatcttcgt gccgtccggg gaccagcggg gggtgagctg cgcgcccggc agggaggtca
     3181 gccgtaccgg ctcaccgccg gtgaggtccc ggcgccacag cgcggccgtt cccgagcggt
     3241 cgctcgcgtg gacgagggcc gtgccgtcgg gggaccagtc ggggtcggag ttgaagaatc
     3301 cgtcgtcggc cagtctgacg ggggcctcgc cggtcttcat cacccacagc gcgttcaggg
     3361 cccggaaggc gacgcgctga ccgtcgcggg agacgaccgg gctcgcgatt cccctggcct
     3421 gctgggccgc ccgggaggtg aagtccctga cccgcggcgt ccagggctta cgggtgaagg
     3481 tgaccgtcgc ggtgaagtcc accgtccggg gggtgccgcc ggggcgcagc cgacggacgc
     3541 gcccgcctgc cgtgtagagc aggtcgccgt ccgaggtcca ggatgtgcgc agggcgtgca
     3601 cgtcctcgcc ggcggcggcc acctggccgt cgatcatgac atcggcgcgg gtccccgtga
     3661 actgtacgta gctcacccgg cgtccgtccg ggctcggcgc cgggccgaag atcttcgctc
     3721 cggcgctcgc ggtgatcagc cgggtcctgg tcccggtcgc cacgtccacg gagtcgatcg
     3781 ccgcgtcgtt caccgtgcag acgatcgtcc tgccgtccgc cgaccaggcg ggggtgccgt
     3841 cctcgtcggg gccggtggtg agctgcgtac ggacgccggc ggccgggtcg agcagccaca
     3901 ggtcgttgct gcccgaccgg tcggaggtga agacgatccg gctgccgtcg ggcgcgtact
     3961 gcggctcgcg gttgtcgtag tcgtcgtcgg tcagccgggt gaggccggtg ccgtcgcgct
     4021 tcaccgacca cagctggtag gcgccgtcgc ggaaggactg gaacacgaca cggctgccgt
     4081 ccggcgccca gtgcggctgg gtggcgtcct ggagttcgcc ggtgagccgg acggcggcgc
     4141 cgcccgcacc ggggaccacc cagacggcgc tcagcacgtc gatggcgagg ccggtgccgt
     4201 cgggagagag ggcggcggcc atgttggtgc cctcggagac ggtgacggtg gcggtacgag
     4261 gcgcaccgcc gggccgctcg gcgggccgcc ccggctccgt gccggccgcg gcggcccggc
     4321 ccgcgctcgt acccccggcg gtcagcgcgc cggcggtcac cgcgccgctc acggccagga
     4381 catgccgtct gctcgggccg ggagcggggg cggggtcggg gttcgtgacg tccatcaggt
     4441 tctcgtgttt cttcaggagg gacatgccgt caggagggac ataccgcgcg caggaagcgg
     4501 gccagccggg caacgccttc cttgatcgcg tcggggtcca agtaactaca ggccaggcgg
     4561 agttggtagt ccccgccgct gcccagatag aagtgggaca tcggagtcca caacacgccg
     4621 aactcgcggg cggaccgttc gagcagccgc tcgtccgccg gtacgggaag ccggacccgt
     4681 acgaagaagc cgccgcgcgg ccggttccag gagaccccgg cgggggcgcc ggtgcccggc
     4741 ccgagcgcgt ggtccagcgc gtccagcaac agacgcagat tgcgctggta cagcgcggcc
     4801 ttggcgctga cgaccgaggc cagcgagccc cggtgctcca gcaggatgcc gccgacgacg
     4861 gcctgggcga tgggcgaggt gttgaccgtc accatgctct tgagggtggc gagttcgtcg
     4921 gcgagcaggc cggtgcggcc cgacgcgtcc cgtacccgct ggtcggcgac gacgtaaccg
     4981 acccgggctc ccggcatgca caccttggcg aacgtgccga gatgcacgac ccgttcaccg
     5041 ccgggcagcg ccttcagcgg cgggagcgcg cccggctggt gcgcggtgaa cgcgtacgcg
     5101 ttgtcctcca gcaggaggaa gtcctcgcgg gcggcgacgt cgagcagccg gtggcggtcg
     5161 gccagagaga ggaaaccgcc ggacgggttg gagaagtccg gcgcgacgta cagggcccgg
     5221 atacggcggc ccgcctcgcg cgccgcccgg cacacgtcgt ccagctgggc gaagtcgatc
     5281 ccgtcgtcgg tgtcgtcgac cgggacgagg tccacgccga gcaggccggc cgccccggac
     5341 agaccgacga agcacgggtt gacgaccgcc acgaggtccg tgggctcggc ggcgagcgcg
     5401 cgcagcgcca gcagcatcgc ctcctggcag ccgaccgtga tcaccacgga ctcgggcggc
     5461 acgtcgatgc cctggtcggt gcggagcgcg cccgccacca gatcgccgat gagaccccgg
     5521 ctcggcccgt actggtagag gagccgttcg gccaggtcgg gcttgagccc ccggtcctcg
     5581 gtgagatggc ggagatagcg gtcgatgtgc cgggggatgt cgatctggtc gaagaagctg
     5641 atgtgcgggg cgcccggcgc gaaggagagc gcgtcgggga agcggcccat cacctcgttg
     5701 aggaagttga tcgatcccat ggcgggagag cccagggaac tgtgcaggcg ctcgcgccgc
     5761 aggacgacac ctgccccggc ggtcaccggc cggtctccgc gccggcgtgc gtgtccgtcc
     5821 tcgtgccggc tgccgcgccg ggctctgtgc cggacttcgg cggatcggtg gccgagggtc
     5881 ccgtccccga ccgcgccgag aaacggccca ccttgtccag cacgtcctcg ccgtagagcc
     5941 gttcggcctg ggtcagcgag aactccgcca tgtacgcgcg gaacgcgtcg accggctcct
     6001 ccgagacacg cagcatgcgc cggttggcga gcacggcggg cgccgccagc tgggtcaccg
     6061 cgtcgtccac cgcccggtcc atcgccttcg ggtcgaccac ctcgtcgatc agcagccggg
     6121 catccggctc acccgcccag atcttgcgtc cgccgagcac cgcctgccgg gccacccggc
     6181 caccggtcag ccgcgccagc cggaagttcg ccgcgccggg cacgatgccc tcctgcgcgg
     6241 cggggaggct gagataggag tcggcggcgg cgatcacctt gtccatcacc agcagcagct
     6301 gggtgccgcc gccgatggcg aacgtctcca ccgccgccac ccacggcttc tccacgccgt
     6361 gcgccgggta ggtgtccggg cgcccgagcg tggacagacc ccggtacatc ttgctgatgt
     6421 agccgagttc gcgctggagc aggaagccgg tgaacgagat ccgcccgtgg tgcagatcgg
     6481 ccagattgac gcccgcgctg aagacccgcc gcccccggta gcgcgggtgg gtcatcggcc
     6541 cgccgcgcag cacccccacc ctgatcccgt cgtccagcag cacgaggtcg acggccactt
     6601 cgagctgggc gatcaggtcg ttgtcctcgg cgttgagaca ggagtcgttg tggaaggtca
     6661 catggcctcc gtcgccgtgc cgctccaccg tcaccttgcc cagctcggcc cgtccggtgg
     6721 cccggaagtc cggcagcagc gcgtgtgccc ggggcgtcgg gtcccgcatc acgtcgacca
     6781 gatgcgcgcc cgcgccgggc agccgcagga tctcccggaa gaagatgccc tggtcgatct
     6841 cccgtccttc cttgtccgcc tgcgcgtggc gcagttcctc ggccagctgg gcggcgtccg
     6901 ggacgagccc ggggaagctc tcggccgccg cgccagccag ctcggtcagc ccgagccgtg
     6961 cgctacgtcc ttcggtcagc cggtcgtaga ccgccgccgc gtgggcccgc aggaaggcgg
     7021 cccgcagctc gcggcaggcg cggtggatcg ccgcggcccc cagctgctgc tcctcggagc
     7081 ggtcggagcg cggcggcagc gcggccagcg gtgcctcgcg gtcacggatc tcggcggcca
     7141 gcgcgaggcc ggcggccgac agctcaccgc cgtcggccgg ggcggccgcg ggggcggaga
     7201 cggatctggg ggagcctgac gtcgacacgc ggttccttcg aaggaggagg gacaggaggg
     7261 gcgtgcgggg tccccgtccg ggcgggcggg gagccgcttc gtaccggtgg tcagcgcgcc
     7321 tgcgccaacg agccgtcggc cggggcctgt tcggccgccg actgtccggc cgtggtacgg
     7381 cggcgcaggc ttcggtcgca cgcggccaga tgggcgccca gggcctcctc gtaactgagg
     7441 gtggcgtcga acagcagcct gcgccgtatc gaccactcgc ggcccgggac ggccgacagc
     7501 tcgcccgcca ccagcaccgc gcggcgcagg gccgcctcgc cgccgtccgc cgtctcgtcc
     7561 accaggtcca gatcagcggc ctgctcaccg tccagccagg ggcggcgcag cagcaggcgg
     7621 cgcgcccgcg ccgtgccgat ctgctgcgcc agccggtgca gcgccgtgct cggccaggcg
     7681 ccgtcctcgg cgcccgggag ccgcaggcgc gcgtcgccgg ccgcgatccg gtagtcggcg
     7741 gtgagcagcg tctccagcgc gggtccggtg caggtgccct ccacgagcgc gagggtgggg
     7801 cgcccagagg tctccagccg gcgcagtgcc cgctcccagg tgttgaccag atggatgccc
     7861 gtaccggcgg ggggcgcgcc ctccgcggcg ccggcgccgc ccagcaggag caggacgaca
     7921 ccgcggtcgg cgccctccgc cttctcggcg gcggtgcgca cccggtcgac cagcgccggg
     7981 gtcagttcct cgtcgccgac cgtcaggacg gcggccgcct cgtcgtggag acggacggtc
     8041 ggggcgttgg gggtatcggt atccgtgccg gacacggtca cacttccttc gtcgtccgcc
     8101 ggtgagggcg gtgagggtgg tgggggcagt ggggatggtt cggtgggtgc cgtgggtgcc
     8161 gtgggtgcgg tcggtgtcat ggcgcgggtg ccgtcaccac tggacgagcg ccgtctcgat
     8221 ggtggagccg gggcccatgg tcatgagcac gccgtagtca ccgcgccgca cccggccctc
     8281 ctccatcagg cgctcgtagg agaacaggaa cgagccgctc gacaggtttc cgtagtcgcg
     8341 cagcaccccg gtggtgtggc gcagtgcgta cgtactgagg ccgaggttga ccttcaccga
     8401 gtcgatgacc ttcttgccgc ccgagtggac cagccagtgg tcgatgtccg cgcgctccag
     8461 accggtgccg ccgagcagcc ggtcgaccac ctcctcggcg ttcgccccga cgacatacgg
     8521 cacgtcacgg tcgaggaaga agctgaactt gccctggtcg tcgtcccagt cgtagcgcat
     8581 cgcgtccacc gcttcgggga tgatgcggct ggcggccttc agtacggtgc ccacgggcgc
     8641 cgcctcgtcg gcctccgccg tctccgtcgc gtgcgcgccg tgcgccgcgc gtgccgttcc
     8701 cgccgggtcg gtgaccatca cgacggccgc cgcgccgtcg ccgaagaggc tgttcaccac
     8761 cgaggtgcgc atggtgccgt cgaagacata ggcggcggag cagacctccg cgcagaccat
     8821 gacggccgcc tgcccggggt tggccgccga ccaggacgcg acggcggcca tggcgttgag
     8881 gccggcgttg cagcccatgc ccacgacgtc gagccggccg gtggagaccg gcagccccgc
     8941 ttccttgacg agatgggcgg agaatccggg tgtgagcagc cccgtggtgg tcacacagca
     9001 caggtatccg acatcggaga gcgcgaggcc ggcccgcttc agggccgtct ccagcgcctc
     9061 cctgcccgtc ctgacgccct gctccttgtg cttggcgagc agttcgccct gggtctcggt
     9121 cttgcgtgtg ccgtcggcca gttcgggcgg cagggtcaga tagcggcgct cgatggcgct
     9181 gttgaggaag acggacctga tccgggggtc ctcgatgccg aacagctcca gcatctcgcg
     9241 ctgtgtgtag gagttggcgg gggtggccgt accgaagccg acaaccgacg gccggggccc
     9301 cgcgttcgcc gtgctgagcc gctgtccggg ggcccgggtc gcgggctcgg tggggacggc
     9361 ggaggaggag gccggggccg tgggtgctgt ggcggtcatg ccggcacctc cagctcgttg
     9421 gtggccagct cgatctgctc ggtggtgtgc gccgccgaga cggccatccg gatcagaccg
     9481 ctgcccttgg ccacggtcgg gaagaacgcg ggggtgacga tgacacccgc cttgcgcagc
     9541 cgcgccgcgg ccaccagcgc gtcctcctcg ctcttgaaga gcgccccgcg gatcggcgac
     9601 cgggtgcccg cgttgaacag cgcgcctccc gtgcgggagt cgaagagttc ggtgttgcgc
     9661 cacaggtccc gctggagccg cgcgaccgta ccgtcgagat gcagctccgc cgacgcccgg
     9721 caggcgctga tgacgggcag cgcgatgggg ccgccgaaga tcagcgggtt gccgaatctt
     9781 cgcagctcga ccgtgtcctc ctcggtgttc agcaggacga agccgccgtt gctgccgccg
     9841 aacgccttgg cgagcgagcc gacgaggatc accgaggcgg gcagcccgcc gggcaggtgg
     9901 cggaactcct cgtacgcgaa acccgccccc tgttcaccgg tgatcgacac accgtgcgcg
     9961 tcgtccacgt acagatagcc ctcggccgcc gcgcacaggt cgtacagcgc ggccacgtcg
    10021 atgagcccgc ccatggaccc cacgccgtcc acgaggacga tcggcgtgcg cccggcgtcg
    10081 cgcaccgccg ccagccggac ggcgaggtcg tccaggtcct cacagtcgaa ccggtccacg
    10141 tcgccgatct gttcgagcac gccgcgcagg acctggatgg acgcgtgcgc ggtgcgctcg
    10201 atcagaaagg tgaccccgct cgccgacacc gggtagctgg gcagcacacc cgttcccagc
    10261 agcggcagca cccccaggtg gacgctgccg acggccgtga agcacgtggc gtgccggccg
    10321 ccgtagacga cgccgagcat ccgctccagc gattcgaggt cctcgtaccg catccgggtg
    10381 cgtgacgagg agaactgcac gccgacccgg cgcaggctgg cgacggccgc ctccaccagg
    10441 gccgggtggg tgtcgaggcc cagataggag cacgagatga actcgacggc gctgcggccg
    10501 tcggcgagcg tcacctcttt cccctcccgc ccggtgaaga catggctggt caggtcggtg
    10561 gcgatggccc gggtcagcgc gtccgacgtc ttgtctacgc gcgtggctac ccagttgtgt
    10621 cgttcgatcg tacgaggcat cggagtgtct ccagggatgc gtacggatgc gtgagaagga
    10681 gcggtcggag cggtggtcgc ggcggcgcgg aaatctcgcg ggagccgcgt gacggacgtg
    10741 cggcggaagg gagttcagcc ggcggtgcgg ttgacgaaga agggtgtctt gccccgtgcc
    10801 gtgtggtgga actcggagct gtcgacccgc tccagcgtca gcccgcggta cagcggcgcg
    10861 gtgaagaccc tccccatgtg gtaggcgccg tgcagcgcgg cgacggcgtc ctcggtcgtg
    10921 accgagggcg gcgtacgttc cgagaccagc agccggatcg agaagcccgg atcgtgctgg
    10981 gtcacctgga actggcagtc ggccgggtcg ctgatgccca gcgtggccag ctgctccatc
    11041 accagatcac gggagatggt ggtgctgtcg acattcatgg acatgcccac ccggcccgtg
    11101 agggtcagct gccgcgcggc gctgccgcac agacaggggc gggtctcgat gaatccctcg
    11161 tcgccgatcc ggtagcgcag cagcggcata ccggagtcgg tgagcatcgt gacgaccacc
    11221 tcgccgaccc ggccgtcggg ctgtatccgc tcggcgtccg tgtcgaccac ctcgaccacc
    11281 agcacgtcct cgtgcagatg gtgggtcgaa ccgctctggt aggtgcactg gtagccgacc
    11341 ggcccggtct cgctggtgga gtacgagaac gaccgcaccc gcagatcggg ccgggcgtcc
    11401 gcgagttgac gctccctgct ctcaccgagg atctccccga tgtacagcag actgtccaca
    11461 ccgcgcagga gttcacgtgt cgcgtcgccg gtcagcagcc ccgtccccgc cgagggtgag
    11521 cagatgaccg cgtccacccg gttctcgcgc agcagctccg ccgtctcggg ggaggcgagg
    11581 gcgctgctgc ccatggggaa cgacatggcc ggcagcagct ccgtgacctc ctgggcgaag
    11641 gtgaacgcgc cgttcagctc gcccgggtag aggaagttgg cgatacggcg gggatgcggt
    11701 cgcagcgcgc tgcgcacccc gcgcgcgccg agagccgaga cccggcggct gaactcccac
    11761 gagtggtaga tcatcttgcg ccgtcccgat gtaccgctgg agcgcaggac gagcccggag
    11821 cggccgtcgc cgagcaccag attctccgat gcgggcggac aggacgcctg gagatcggcc
    11881 ggtgagaaca gggggagttt gagcagatcg cgcggcaccc gcacgtcgag cgcgccgggc
    11941 cagcaggcgg ccaccgccgg attccccttc agggcgtcca cggtgcgggc gagattgcgc
    12001 tgctgcattt cgtcgagctg cgcccgcgtc agaatgtcga gattctctgc cagttcaatc
    12061 tttgacgact caccggcacg cgcctcgctg tggtgcgagg tcggatacat ttcccccagc
    12121 acgatttcct cacttggtcc actgttcaac agatttacct gtccgcacca ctcgaccgag
    12181 gcacgctttt cggccattgc accgctgccg ccgggccgga aatagttgaa ttccgatttc
    12241 ttccgcatat gccccgacgc gctcgtcacg gcggtacgtt cgctgccgcg ggccgattcc
    12301 cgttccggtc cgcggtcccg tatccgggcc actccggcgg gcggcggccg ttgaacgcgg
    12361 cgacgccctc cgcccagtcg gccgagaagg cgaccgtgtg ccaggcggcg tcctcgactt
    12421 cgagccccgc cgccagatcc cggccctgac ccagtcgcag cgcgcgcttg gcggcacgca
    12481 gcgccaccgg cgagttggcc gcgtaggtac gcgcgaggtc gagagccgtg gcgcggaccg
    12541 cgccggcggg cgcgagaacg tccaccagcc cgaggtcgcg tgcctcggtg gccggtaccc
    12601 gtcgcccgct gaagatcagc tgggccgcga cggccgcccc gaccctgcgg ggcagcagct
    12661 gcgtaccgcc gccgcccgga atgaccccga ccgtggtctc gggcagcccc acggtcgcgc
    12721 cggggtccgc cacgatgacg tcgcaggaca gcgcgatctc gtagccaccg cccagcgcgt
    12781 agccctgaac agcggcgacg accggcatgg gcagcgccag tacacccgcg tacgccgccc
    12841 ggctgcccgg ccgcgccgcg gcccggtcgg cctcggtgta gccggcacgt tccttgagat
    12901 cggcgcccac gcagaaggcg cgttcacagc gggaggtgat gacggtgacg ccgacggagg
    12961 ggtcatgtcc gagatcagcc gtcgcgtcgg ccagcgcggc gccgaagtcg gcggaaaccg
    13021 cgttcatgcg ttctggccga ttcaggacca gttcggcgat ccggccgttg tgtgtgcggt
    13081 gaacgagaat gtactctccg tagcgcagtt cggacatcac gccctgcccg gtccgggatc
    13141 agggccgatg tccgccatcg acggtgagca caccgtccca cggtgaattt cggccacggt
    13201 cgaatatggc acggctggac atgtgattgc gcgcagcacg actcgcttct cccccgacgt
    13261 aatcagtgcc tgatacgacg taaatctgcc atctgccgag agggggccgc cagtgcgcat
    13321 gcacgtcgta atgccgccag gcgagaatgc gacgggccga aaacccgcca aattgcctga
    13381 acggattaat ctggaatttt cggacatgag gtagtgcagt gaatatgcca gctcaccatg
    13441 ttgatcgctc cccgctcccg atagacgagg agatcacctc ggcctacgca ttcctctgcg
    13501 gttcggggaa cgcgtccgtc gagcagatcg ccgccgcgct ggaaatcgga atcgaacggg
    13561 cgcggcaatt ggtcggccgc ctcacggagt tacacctgat cgattccgcc ggggacggca
    13621 cgtacacacc gggatcgccc cgggcgctcg gcgccggcgt catcgccccc gccatcaggg
    13681 agttggagag cggccagcag cagatcatca ggatgatgac ggagctggac gccctcacca
    13741 agatctacga gcggagtccc gccgagcggc tgcgccggcc ccggatcgag atcctgcccg
    13801 aggtcaccgc cgtacgggcg gtcctgaccg aactctcggc gggggcgcgg acggagatcc
    13861 tcacctccca gccgggcggc gcccgccccg ccgatgtgct gcgcgagtcc ctcgaacgga
    13921 cggaagcggt gctgagccgc ggcatcacca tgcgcaccgt ctaccagtac accgcccagt
    13981 tctcacaggt cacggtggac tatgtccgcc atgtgacgga gcggggcgtc gaagtgcgca
    14041 tgctcggcga cgccttgatg cggatgatca tcttcgaccg ggagatcgcg gtcctgccgc
    14101 agtacgaccg ggacggtgcc gtggtcgtca gcgaccggag catcgtggac ttcgccgtgc
    14161 aggcgttcga acgcgcctgg ccggtggcga ggccgttccc cgtctcgtac gaccggggcc
    14221 aggtcaagag cacctcggtc gaaatccagc tctccatctc acggttgctg gtggaagggc
    14281 tggaggacaa ggtgatcgcc cgccgcatgg gcatgtcgct gcggacctgc cagcgccaca
    14341 tctcggagat catgtcgcgc atcggggccc gcaaccggat gcacgcgggc tatctcctgg
    14401 ggaagctgat cgacagtcag aactgaccgg gcaccggagc tccacgctca ggaccggtcc
    14461 cgggcggacg aggctccggg cgagtcgtcg ggtgagccgt ccggggaacc atcggcggaa
    14521 ccgccgggcg cgacctcggg cgtggccttg gcaccgcccg agggcacgac gtaccgggtg
    14581 acggcgagac cgcccacgag cagcaccagc cccgccagca cacccacccc catgccgaag
    14641 tgggccggct gcggcagcca ggacgcggag gtgctgaccg cgagcccggc cgccatgttc
    14701 ccgcagatct caccgatggc cgtgaccagg ctgacgaggg cgatgacatc cgtcagccgt
    14761 gtctgcggca cggtgtccgc cgcctccacc tggatcttcg ggaaggccag acactccgcg
    14821 acggcgaaca gcgtcagccc cgcgaggatg agcgtcagac tgccgctgaa ggagagcacg
    14881 agccccgtgc ccccgcccac cgcgacgatc agatacagcg cgcggcgcct cagccgggtg
    14941 aagaacggca ggagcgccag ctggatggcg atgatcgcca gcggctggaa gctgaggaac
    15001 agcgtccggt gctccgcctg ggcggggttg accacctcgt acagcaggat catcgcgtag
    15061 aggaacccca tcgcgaagta gatcgcgaag gtgtagccga gcaccaccgc caccgcgggc
    15121 gtcctgagga cggtgagccg tccgcgcagc ccgttcgcac cccggggcgg cagcgcgaag
    15181 tcgagccccc gggcgaggag tccgacggtg atcccgatca ccgtctcgac gacggccagg
    15241 acgagcagcg cgggaacccc ggcccgcccg accggccccg ccgcgagcgg cgccagcaca
    15301 taggcggtgt tcagcaggat gaagaagacc tggaaaacct ggctgcggcg gtcgtcggtc
    15361 gccgcggcga ccaacaggga acgcaccgcg ggacgtgaga tgcccacgcc gagaccggcc
    15421 agcaccgcga agagatacag cgccggggcc gaggtgctga cggcgacggt gacgaatccg
    15481 gcggccttca gcgacgaggc gatcgtcagg acccaggccg gatggacccg gctgaacgcg
    15541 atcggcgtga ccagcgcgcc gaccagggcc gagccgacat gcacggacag cgcgaaggag
    15601 aagacggacg gctcgatccg cccgccgtgc aggaccgcca ccggaagcag cgtgagcacc
    15661 atcgccagac cgaagttgga cagcagggtg aaacccagcc ccgctcccac ggcccggggg
    15721 taccagcccg ccttcggcgt ccccgtctcg gtggccgttc ccgtcatgcg ctgtgcgccg
    15781 gggcgggctc ggacagcagc cggccgaccc acgggaagaa cgcgtcggcc agctgcgacc
    15841 gggcgggctc gggcatcgag gagaactccg ccatggcggt gccccactcg ccgagcaccg
    15901 gcccgtcgtc ggtcagcagc cagtccacac agagatatcc ggcttggaga tccgcgacaa
    15961 tccgctccac gtcaccgagc acggtcgcca cgtccgggtt ggcgctcgaa ctgccgccct
    16021 gggtgatgtt ggcgaggtac gcgccctccg ccgggctgcg cagcatgctc gcggcgaact
    16081 tcccgtcgac catcgccacc cgcagatcac ccttgttggg caggtactcc tgcacgatgt
    16141 agctctgccc ggtctgggac gcgatgtcga cggcggcccg caactgctcg tagctgtcca
    16201 gcttcagcac accgaagccg atgcccatct cgcgcgcctt gaggatgtac ggcccctcgc
    16261 cgatctcctt gcggacgacg tcgagcccct tgcgcgcgta gcgcccgaag ggcagcgcca
    16321 ccgtcttcgg cacccgcacc ccgagcgtcg acgcacgggc caggatcgcc agcttgtcgc
    16381 gctccaggca ctccggcccg acgagcgagc ggttgagcag gacggagtcg ctggcgtcga
    16441 tggcccggta gatgccccgc aggaaatggg tggcctgcgg atcgccgctc acatcgtcca
    16501 cgatgtacgc ctgccgcgtc cggagcagat ccaccccgtc gtgccacagc cgggggcgct
    16561 cgtcgcacgc gggcacgagc tcgttcgcgc tgatgaaccg gaaggcgaat ccgtgcctct
    16621 cacagggctc cgcccagcgc tccgtcatct gctcggtgat cttgtccacg tactccggca
    16681 gaaagtcgtc cggatggcag atccacgtca ccaggcgctc attcgccacg atcgcaactc
    16741 ctacgagaga cctcatcggc atgtgacggc acccccgcga cccactccga ccgctgcacc
    16801 gacgacgtct cactctttca ggattccggc cggcctctcg tccctccggg ggctcggatc
    16861 ttcgccttgc gccgatgcga caggggtgcg gggcggccga ccccgcgacg ggcctcaggc
    16921 cgtgcgccgc agcagcgcca gatacatcgc gtccgtgccg tggacatgcg gccacagctg
    16981 gacgtcgggg ccctccccca gcgccgcgac gccgggcatc agcggccggg cgtcgaccca
    17041 ttcggcctcg gcggcggggc cgcccctgcc cttgagcacg tcctcgacca cgacgcgcgt
    17101 ctcggccagg tgcggggagc acgtggcgta gccgaccact ccgcccaccc gcacggcctt
    17161 cagcgcctcg cgcagcagtg accgctggag tggcgcgaag ccctccaggt cctcgggacg
    17221 acggcgccag cgggcctccg ggcggcggcg cagggcaccg aggccggtgc acgggacgtc
    17281 gaccaggacg cggtcgaaga cgccgggccg ccacggcggg cgggtgccgt cggcggtgat
    17341 cacctggtac gggccggggt tgcccgcgag cgcgcgctcg accaggcgcg cgcggtgcgg
    17401 ctgcttctcg gaggcgagca gccgcgcgcc ccgctcggcg gccagcgcgg ccagcagcgc
    17461 cgctttgccg ccggggcccg cgcacccgtc gagccaccgg ctgtcggtgc cttccagcgg
    17521 cgcgttggcg agcgccacgg cgacgagctg gctgccctcg tcctggactc cggcccggcc
    17581 ttcgcgtacg gcgtcgatgg cgcccggttc gccgccctcg gtgagccgga ccgcgtacgg
    17641 ggaccagcgt cccggcagtc cggactcctc gcccagtgtg tcgaggagtg cgtcggccga
    17701 gacccgtccg gggcgcgcga cgagcgtcac ctccgggcgt tcgttgtccg cttcgagcag
    17761 gtcctcgatg ccggcccggc cgcccccgag cgcgtcccag agcgcggaga cgatccagcg
    17821 gggatgggag tggacgacgg cgaggtggtc ctcggcgtcc tcgtcgtacg gcggtgcgac
    17881 ccgctccacc caggcgtcga ggccgtcctt ggagatcttc cgcagcacgg cgttgacgaa
    17941 cttcgcgcgg ccgtcgccga gcacgacgcg ggcgagctcc acactcgccg acacggcggc
    18001 gtgcgtggga atccgggtgc cgagcaactg gtgcgcgccg agggccagta cgtcgagcac
    18061 gggcgggtcg acctggcgca gcgggcggtc gatgcaggcg gagatgatcg cgtcgtacgt
    18121 gccctggcgg cggagcgtgc cgtagaccag ttcggtcgcg agcgccgcgt cgcggttgtc
    18181 gaagtcaccc gcctccctgg ccttcttgag gaggggcggg aggacgaggt tggcgtaggc
    18241 ggcgcgttcg tcgacggccc gcaacgcctc gaaggcgagg atccgcacgg gatccttctt
    18301 gggacggcgg taggtcttgg agggacggcg acgtgcctgc tcgttcaaag gtgctccgca
    18361 gttgaaaagg tgctccgcaa aagtgccgcg cgttcagggt gccgtggtac cgcgcgtggc
    18421 ggtgggacac cctcagcgta cgtccgcggc cccctcggcc gcgccgagcc gctcaccggg
    18481 cgcgatccgc acgccgcggg cccagtcggc ggccctcatg ggcttcttgc cctgcggctg
    18541 gacccagagc agctcgacgg cgtacgagcc ggtgccgacg tgcacggagt tcttgccgac
    18601 ggccggctcc ccgggcgcga ggtcggtgcg gtcgggcacc ggcttgagct ggatcagctt
    18661 caggcgttcg ccgcggaaga cggtccaggc gccgggcgcg ggggtgcagc cgcgtacgac
    18721 acggtcgaca cgcagcgcgg gcgccgccca gtcgacccgc gcgtcctcga cggtgagctt
    18781 gggcgcgagc gagatgcctt cggtgggctg ctgtacggcc ttgagggtgc cgtcctcgat
    18841 gccgtccatg gtcgcggcga gcagtccggc accggcgaac gcgagcctgg tcagcaggtc
    18901 accgctggtg tcggtgggcc gtacgtcctc ggtgatcacg ccgtacaccg gtcccgagtc
    18961 cagcccttcc tcgatgagga aggtcgccgc gccggtcgtc tcgtccccgg cgatcaccgc
    19021 gtgctgcacg ggcgcggcgc cacgccacgc gggcagcagc gagaagtgca gattgaccca
    19081 gccgttggcc gggatgtcga gggcgacgcg gggcagcagc gccccgtagg cgacgacggg
    19141 gcagcagtcg ggggcgatct cgcgcagccg ggtcaggaag gcctcgtcgc ggggcctggc
    19201 gggccggagg atctcgatgc cctcctcttc ggcgcgctgc gcgacggggc tggcgacgag
    19261 cctgcggcca cggccggcgg gcgcgtcggg gcgggtgacg acggcggcga cctcgtgccg
    19321 gtcggaggcg atcagtgcgt ccagggctgg tacggcgacc tcgggggtgc ctgcgaagac
    19381 gagcttcac
//
