BGC0002035: ilicicolin H biosynthetic gene cluster from Neonectria sp. DH2
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Location: 1,095,186 - 1,116,947 nt. (total: 21,762 nt).
This entry is originally from NCBI GenBank RQWH01000002.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0002035
Short description ilicicolin H biosynthetic gene cluster from Neonectria sp. DH2
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
RQWH01000002.1
1095186 - 1116947
via
Compounds
  • ilicicolin H
  • ilicicolin J
  • 8-epi-ilicicolin H
Species Neonectria sp. DH2 [taxonomy]
References
Chemical products information
ilicicolin H Evidence:
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C27H31N1O4
Chemical database entries
PubCHEM
ilicicolin J Evidence:
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8-epi-ilicicolin H Evidence:
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List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • iliE
 1096581 - 1098326 (-)
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    • iliA
    		 1098611 - 1110775 (-)
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      • iliB
      		 1111654 - 1112799 (+)
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        • iliD
        		 1112945 - 1114530 (-)
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          • iliC
          		 1115245 - 1116781 (+)
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            Biosynthesis information

            Biosynthetic modules

            Name
            Unk01
            Type
            nrps-type1
            Genes
            iliA
            Substrates
            tyrosine (evidence: Structure-based inference)
            Integrated Monomers
            Domains
            adenylation
            Annotation changelog

            Entry version: next

            Date
            Changes
            Submitters
            Reviewers
            2024-08-09
            MIBiG v4 annotathon
            • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 2

            Date
            Changes
            Submitters
            Reviewers
            2022-09-15
            Use gene names as per publication
            • (ID: 3UOU7PODQJXIM6BEPUHHRRA5)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2022-09-15
            Add structures for ilicicolin J/ 8-epi-ilicicolin H
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2022-09-15
            Fetch compound properties from PubChem
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2022-09-15
            Added NRP substrate specificities
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 1

            Date
            Changes
            Submitters
            Reviewers
            2019-10-16
            Submitted
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            Detailed domain annotation
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            Similar known gene clusters from MIBiG 4.0
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            Modifications to original record
            • iliE was added
            • iliA was added
            • iliB was added
            • iliD was added
            • iliC was added