BGC0002035: ilicicolin H biosynthetic gene cluster from Neonectria sp. DH2
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Location: 1,095,186 - 1,116,947 nt. (total: 21,762 nt).
This entry is originally from NCBI GenBank RQWH01000002.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0002035
Short description ilicicolin H biosynthetic gene cluster from Neonectria sp. DH2
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: RQWH01000002.1
Compounds
  • ilicicolin H
  • ilicicolin J
  • 8-epi-ilicicolin H
Species Neonectria sp. DH2 [taxonomy]
References
Chemical products information
ilicicolin H
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C27H31N1O4
Chemical database entries
PubCHEM
ilicicolin J
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8-epi-ilicicolin H
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List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • iliE
 1096581 - 1098326 (-)
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  • iliA
 1098611 - 1110775 (-)
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  • iliB
 1111654 - 1112799 (+)
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  • iliD
 1112945 - 1114530 (-)
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  • iliC
 1115245 - 1116781 (+)
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
iliA
Module ?
Specificity: tyrosine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: 3UOU7PODQJXIM6BEPUHHRRA5, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Use gene names as per publication
  • Add structures for ilicicolin J/ 8-epi-ilicicolin H
  • Fetch compound properties from PubChem
  • Added NRP substrate specificities
Detailed domain annotation
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Similar known gene clusters
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Modifications to original record
  • iliE was added
  • iliA was added
  • iliB was added
  • iliD was added
  • iliC was added