BGC0002038: nigericin biosynthetic gene cluster from Streptomyces sp. DASNCL29
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Location: 914,857 - 1,009,902 nt. (total: 95,046 nt).
This entry is originally from NCBI GenBank VCNB01000001.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002038
Short description nigericin biosynthetic gene cluster from Streptomyces sp. DASNCL29
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
VCNB01000001.1
914857 - 1009902
via Enzymatic assays
Compounds
  • nigericin
Species Streptomyces sp. DASNCL29 [taxonomy]
References
Chemical products information
nigericin Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • FGK60_03725
  • TMU97084.1
 914857 - 915534 (+) hypothetical protein
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    • FGK60_03730
    		 915576 - 916430 (+) polyketide synthase
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      • FGK60_03735
      		 916728 - 917129 (+) hypothetical protein
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        • FGK60_03740
        		 917883 - 923857 (+) SDR family NAD(P)-dependent oxidoreductase
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          • FGK60_03745
          • TMU97085.1
          		 923797 - 924264 (+) SDR family NAD(P)-dependent oxidoreductase
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            • FGK60_03750
            		 924153 - 924338 (+) KR domain-containing protein
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              • FGK60_03755
              		 924317 - 924433 (+) KR domain-containing protein
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                • FGK60_03760
                		 924546 - 924965 (+) hypothetical protein
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                  • FGK60_03765
                  		 924990 - 926372 (+) polyketide synthase
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                    • FGK60_03770
                    • TMU97086.1
                    		 926396 - 926593 (-) hypothetical protein
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                      • FGK60_03775
                      • TMU97087.1
                      		 926665 - 928164 (+) acyltransferase domain-containing protein
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                        • FGK60_03780
                        • TMU97088.1
                        		 927993 - 929906 (+) SDR family NAD(P)-dependent oxidoreductase
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                          • FGK60_03785
                          • TMU97089.1
                          		 929954 - 936577 (+) SDR family NAD(P)-dependent oxidoreductase
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                            • FGK60_03790
                            • TMU97090.1
                            		 936696 - 942518 (+) SDR family NAD(P)-dependent oxidoreductase
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                              • FGK60_03795
                              • TMU97091.1
                              		 942515 - 942952 (+) nuclear transport factor 2
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                                • FGK60_03800
                                • TMU97092.1
                                		 942988 - 943455 (+) hypothetical protein
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                                  • FGK60_03805
                                  • TMU97093.1
                                  		 943489 - 944919 (+) FAD-dependent oxidoreductase
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                                    • FGK60_03810
                                    • TMU97094.1
                                    		 944916 - 948782 (+) SDR family NAD(P)-dependent oxidoreductase
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                                      • FGK60_03815
                                      • TMU97095.1
                                      		 948819 - 949229 (+) phosphopantetheine-binding protein
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                                        • FGK60_03820
                                        • TMU97096.1
                                        		 949313 - 950572 (-) cytochrome P450
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                                          • FGK60_03825
                                          • TMU97097.1
                                          		 950744 - 951598 (+) alpha/beta hydrolase
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                                            • FGK60_03830
                                            		 951869 - 952222 (+) ABC transporter permease
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                                              • FGK60_03835
                                              		 952311 - 952913 (+) hypothetical protein
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                                                • FGK60_03840
                                                • TMU97098.1
                                                		 952953 - 957974 (-) acyltransferase domain-containing protein
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                                                  • FGK60_03845
                                                  • TMU97099.1
                                                  		 957991 - 970146 (-) SDR family NAD(P)-dependent oxidoreductase
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                                                    • FGK60_03850
                                                    • TMU97100.1
                                                    		 970189 - 982554 (-) SDR family NAD(P)-dependent oxidoreductase
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                                                      • FGK60_03855
                                                      • TMU97101.1
                                                      		 982571 - 994720 (-) SDR family NAD(P)-dependent oxidoreductase
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                                                        • FGK60_03860
                                                        • TMU97102.1
                                                        		 994762 - 1001502 (-) SDR family NAD(P)-dependent oxidoreductase
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                                                          • FGK60_03865
                                                          • TMV00153.1
                                                          		 1001505 - 1008794 (-) acyltransferase domain-containing protein
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                                                            • FGK60_03870
                                                            • TMU97103.1
                                                            		 1009090 - 1009902 (+) methyltransferase domain-containing protein
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                                                              Biosynthesis information
                                                              Annotation changelog

                                                              Entry version: next

                                                              Date
                                                              Changes
                                                              Submitters
                                                              Reviewers
                                                              2024-08-09
                                                              MIBiG v4 annotathon
                                                              • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                              Entry version: 1

                                                              Date
                                                              Changes
                                                              Submitters
                                                              Reviewers
                                                              2022-09-15
                                                              Entry added
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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