LOCUS       BGC0002039             30309 bp    DNA     linear   BCT 21-NOV-2019
DEFINITION  Nocardia interforma ATCC 21072.
ACCESSION   BGC0002039
VERSION     BGC0002039
KEYWORDS    .
SOURCE      Nocardia interforma ATCC 21072
  ORGANISM  Nocardia interforma ATCC 21072
            Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Nocardia.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 06:14:23
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 30309
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..438)
                     /gene="orf-1"
     CDS             complement(1..438)
                     /codon_start=1
                     /gene="orf-1"
                     /product="hypothetical protein"
                     /protein_id="AVW82896.1"
                     /transl_table=11
                     /translation="MATWPELSPAEQQQKLAEITGEILPTLPHGWSRLVVRARMIGPHS
                     EADTGVKMPDGSVRGWSFPPEVWRKFQQLRKGMYAEGLGSWIEFEYVLDPPGRFTIRYN
                     RDEAPEFEAAPSPENFATEQKWFPRNDSLMPEWFRAGLAAA"
     source          1..30309
                     /culture_collection="ATCC:21072"
                     /db_xref="taxon:1311815"
                     /mol_type="genomic DNA"
                     /organism="Nocardia interforma ATCC 21072"
                     /strain="ATCC 21072"
     misc_feature    1..30309
                     /note="formycin and coformycin biosynthetic gene cluster"
     subregion       1..30309
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..30309
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(473..2059)
                     /gene="focS"
     CDS             complement(473..2059)
                     /codon_start=1
                     /gene="focS"
                     /product="fumarate reductase/succinate dehydrogenase"
                     /protein_id="AVW82897.1"
                     /transl_table=11
                     /translation="MVIAGSGGAGLLAAARAAAAGLSTVVLERSESLGGTTAVSGGMLW
                     IPDSSVMRRAGLPDSAEDALRYLEPVVEGTVGRERLEHYVRTAPEMLDWLEEHTGARFF
                     PIDRPDYHSDWPGAVDVGRCVDNEPFETAPFPGLLERLRRGPQFPPLTYDERHRSRFTG
                     PDESLLAQRREQGVLTVGAALAAALVAACDALGVEFVTGARATTLVFSQGKVSGVRCED
                     GRTFAARAVVLANGGFEWDPASGAFLGDTPVVPVSPPVNTGDGLRMALSAGAALERMNQ
                     AWWVPALRGVPEEYDGAPLTRHLVGERCLPGSIMVDRHARRFVNEAVNYHDITRVLFNF
                     DADGHRPAHLPVWLVFDEKFRTSYNVGPASPRDPAPSWLTSAATPALLAEALGLDPAEL
                     TKTVDRFSAHARAGSDPDFHRGETSHDRYYGDPRVPGNPCLGELVTPPFHAVEVVPGAL
                     GTKGGPVTSTSGEVLTASGEAVPGLYACGNVSAGVFGPGYPGSGGTLGPALTAGYAVGG
                     ALAEALSQAPL"
     gene            2574..3512
                     /gene="focE"
     CDS             2574..3512
                     /codon_start=1
                     /gene="focE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083:oxidoreductase (Score: 53.1; E-value: 5.2e-16)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative monooxygenase"
                     /protein_id="AVW82898.1"
                     /transl_table=11
                     /translation="MDMTGPVTELVATALAAETAGADYLVLPDRTAAVPDGASPATALI
                     AAAFLAARTEDVGIVVAAATSYHEPYSLARQTASLDHISAGRAGWFAGSATDPASDANH
                     RRECHDPARDPQARAREFVPLVRALWDSWEDGAFVHEKATGRFVDADRIHTVDHVGEAL
                     AVRGPLNVIRPPQGQPVVFARATDAVAEHADIVFSAAPQQDHALAVIPFIAADEAAARA
                     LHAAAGSPEGDADHAVVVGTPEQVAARLDHPHVLVRCTARGQLTAFIEQVLPLLKKKGP
                     AGTTLRARLGLAPAPNRFARSEDEELISNAR"
     gene            3502..4836
                     /gene="focD"
     CDS             3502..4836
                     /codon_start=1
                     /gene="focD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083:oxidoreductase (Score: 103.9; E-value: 1.8e-31)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative monooxygenase"
                     /protein_id="AVW82899.1"
                     /transl_table=11
                     /translation="MPAERELHLGLMFWATGTHQAGWRHPDASPDAAYDVGLIQEVSRT
                     AERAKLDFVFLGDRLACDPSLQHSNPAQISRLEPFAAATAIAAATTHIGVVVTANPTYS
                     DPYGVARNLASLDHVSGGRAAWNLVTGADAAAALNYSREQHWDTQKRYEWAEETLEIAR
                     KLWDAGDEPIHHRSEYFQIDGPLGLPRPPQGQVVLLNAGTSDQARELGARQADMVFAGP
                     QPTLAKRKEYYADIKARAARYGREDHVTVVPGLTPIVAPTTEEAVALHDELNSLILLDP
                     EVEVGDLVRAGGIGEGLKRNLTSASEAFGVDLRGNDLAAVVPAEVLAKVSEDGKRRLAE
                     ITRLTRRTAEGPDRITYADLVHVTPQQLSHVVVGNPEEIADEIQLWFEERMADGFNIYP
                     AYVPGSVTAFTELVVPVLQQRGLFRKDYRGRTLRDHLGLEVPARR"
     gene            4913..5752
                     /gene="focG"
     CDS             4913..5752
                     /codon_start=1
                     /gene="focG"
                     /product="transcriptional regulator"
                     /protein_id="AVW82900.1"
                     /transl_table=11
                     /translation="MSVQLLREESAHGSAWKPADHVIVPISLLREADTPRQAGIDAEHV
                     RVLTGVEDLPPIVVHRHSMRVIDGVHRVQAALARGEGEIAVIFFDGDDAAAFVLAVEAN
                     GGHGLPLTLADRRAAALRIVRAYPEWSDRRVASVAGISPKTVGAVRARMSSEEIPQPTH
                     RVGLDGRSRPVHPRAEPARATEERAPVSPQAQRRPPGREAIHGAVVYALRRDPSLRFSE
                     NGRTLLRMLDLHSMSPAGWSEIGDAVPAHCASMVADLARECAEAWLQFADGLDEKSA"
     gene            complement(5797..6852)
                     /gene="focR"
     CDS             complement(5797..6852)
                     /codon_start=1
                     /gene="focR"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103:FAD dependent oxidoreductase (Score: 169.4;
                     E-value: 2.3e-51)"
                     /gene_kind="biosynthetic-additional"
                     /product="glycine/D-amino acid oxidase"
                     /protein_id="AVW82901.1"
                     /transl_table=11
                     /translation="MKVLVIGAGAIGACAALRLAEAGARVTVLSREEPLTTLSAHSFGW
                     ANAIDEKNSAYYDLSIEALAAQQRLVADVGEAPQWLFRHGNLHWGRDEASAEAQQAIAD
                     GYRELGYPVEELTVAQTRELEPGLALADVAGPVHFYPRDVHVLGHVLLPAVLDKAQEAG
                     AEVRIGTAGSLDEAREGFDAVLCCAGRGNADLLPGLPLLEPGAPERLTRGLLVRTTPVA
                     EPVTRIIHAPGLSIRPHTGGRLVLHCHDLDRTLTGDGDVSAVAQQVLERLPAVLPNAAD
                     AEVEHVFTGVRPMPRDGMSIVGPVPGQDGVYVIATHSGLTLAPVLGEIAAREVLGEEHP
                     LVEQFRLTRFA"
     gene            7018..8259
                     /gene="focM"
     CDS             7018..8259
                     /codon_start=1
                     /gene="focM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 78.4; E-value: 9.4e-24)"
                     /gene_kind="biosynthetic-additional"
                     /product="phosphoribosylglycinamide synthetase"
                     /protein_id="AVW82902.1"
                     /sec_met_domain="ATP-grasp (E-value: 8.4e-08, bitscore:
                     22.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRSVLFVNLRRIKREGFESLVAARRLGYRVVLLGRALPEFATE
                     LVDEFHQVDTYDTELALKTAREIAANNDIAGVVNFTEIDVQLVAAIAAELGLPGMPVEA
                     AVRARNKLAMKNALTHIDGVLPKFARVGDLADLREAVAHIGFPCVVKPTGASGSKGIFE
                     LHGEADLEPAMAELSRIADPAFDAVFRQFGAEFIVEEYLTGDELSVEGFVAAGQVHSLL
                     LTDKVTTVPFHLEVSHRLPSVLPAAAQEQIMARAAEIVLALGFDNCSFHLEAKWDGERM
                     GFIEVAARPAGDYIASHLVKAATGVDFFANVIRVATGEPLRLTPDRDLHAGLRFVFAEH
                     EGTFDGLDGVTELFEEPGYDHVFTEVTPGSRVALPPANFGSQRVAAVCARANSREGLDA
                     LLDAAGDQIKVRLS"
     gene            8340..9521
                     /gene="focL"
     CDS             8340..9521
                     /codon_start=1
                     /gene="focL"
                     /product="saccharopine dehydrogenase"
                     /protein_id="AVW82903.1"
                     /transl_table=11
                     /translation="MRLTLLGCGRMGRGAGYALARDPRTTSITLVDRDHDQARALADWL
                     SGRADCEVRVGDAGAVEGSDAVAAALPWGATREAVELAAKAKVPVASITRPPEAESSTV
                     DELARAAGIPVLVPVGLEPGLSELAAADVARRLTALTGGVRTLEVFCGGVPAVPREPWG
                     YTAFFGGELANHLPIAQRTSLAVEHGQVVGHPRFSGVEQRHVPGVGELEAYHDGMVPWL
                     AEHPALADADCTQKTLRWPGFAQAVTGLATLGLLDESPVVVDGVDVAPKRVVEHVLAPR
                     LRAGPEDEDVVVLEVSGTGLPDADGNTVSVRALLVDRADPETGLAAMTRTTGFTLAAAT
                     ALLGERAIVETGWLRPHLALTAEHFARIKADLAALGVRWSADGEGRHTSEGSD"
     gene            9521..10831
                     /gene="focK"
     CDS             9521..10831
                     /codon_start=1
                     /gene="focK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 378.9;
                     E-value: 4.7e-115)"
                     /gene_kind="biosynthetic-additional"
                     /product="L-lysine N6-monooxygenase"
                     /protein_id="AVW82904.1"
                     /transl_table=11
                     /translation="MSTGHDVLDVVGIGIGPANLSLAALLAGQDSGLKVAFLDRKPRFG
                     WHAGLMLPDVQMQVHYLKDLVTPVDPTSPYSFPAFMVDTKRFYRLLVSGRSKVPRREFE
                     QYCRWAAERIPNLRFGVEVRDLTWNGELFVVRTDQGDLLARNVVSGTGLAPRLPSFASG
                     HDPEQVFHASTLLDVPRKLQGRRIVVVGGGQSGAEVVHHLLTVPDRPASIVWGTSRTNL
                     LPLDDSPFVDELFVPNYSRYFHSLPAKRRVELVEEQKMASDGISAGLLEAIYRRLYDLE
                     VLEGEHRPCRTLLGHALTTVEKTPSGLLTRWMPNAGDEVGIEADVVICATGYRHGLPRP
                     LYGLPSTLLAAMSGDDGEIAVRPDFSLDWDGPGDRRVFVQNAARHSFGVADPNLSLLAW
                     RSATIANSVLGFERYPVAEVSTVLDWPPGSSDVALTH"
     gene            10857..12863
                     /gene="focJ"
     CDS             10857..12863
                     /codon_start=1
                     /gene="focJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MannoseP_isomer"
                     /gene_kind="biosynthetic-additional"
                     /product="methionine-tRNA ligase"
                     /protein_id="AVW82905.1"
                     /sec_met_domain="MannoseP_isomer (E-value: 9.6e-12,
                     bitscore: 35.9, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVSEVPRELADLARADFVRSVAPQWAQAADAPFNVRRVTLRPGE
                     ITAEHNHHDLEVWVMLDGSGEVTWDGRRRVITAGDSVYLPPLAPHTLRNLSGDRPLSFF
                     SLWWESLPALAAVHAERQVVERQGRPVLLLPSFPTPNGELHLGHLSGPFLNADACRRAL
                     LAAGERAALLLGTVGHQSQVSAAAQAEGVSFHELAERNTDAITEGLTAASVEWDVFVRP
                     SEPAYPAMATAVFESLRDRGVLVRRTEPTNFCEPCDRFLLEAFVAGRCPHCGSDQTAGI
                     ECELCALPYHDRDLVDPSCSTCGTAAVQRPLTRYFLPLEPLRDRLTDYLRGTAMHGRLR
                     AYVERVLAKPLPDLPVSIPAEHGIPIHVEDAEGPAGQRMYSAFELTARFLVALDGLTGG
                     WESYARRENPRTVLFFGFDNAFLRAFAFPAVLGAFTDALALPEALVCNDFYLLDGEKFS
                     TGRKHAVWLREAAGSANADQLRLYLAATSPDVRRRDFTAQGYAEFVTGELIGRWQGLLD
                     DVGGRIAERFGGTAPEAGGWHAEAERFYGQIKELASAATLDYLPGRFKPRAVVAAVSTL
                     VRQAEDFAEVSADATPGSGLARTCAALELMAVRTLAMAITPLAPEAGGRIAAALGEDAI
                     ALDATPRWVRSGAGIKFPTDLFDHDTTIARGLK"
     gene            12860..14161
                     /gene="focI"
     CDS             12860..14161
                     /NRPS_PKS="Domain: Aminotran_3 (43-343). E-value: 1.2e-50.
                     Score: 164.3. Matches aSDomain:
                     nrpspksdomains_focI_Aminotran_3.1"
                     /codon_start=1
                     /gene="focI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 238; E-value:
                     2.9e-72)"
                     /gene_kind="biosynthetic-additional"
                     /product="aminotransferase"
                     /protein_id="AVW82906.1"
                     /sec_met_domain="Aminotran_3 (E-value: 7.1e-53, bitscore:
                     170.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSASTYESVSAASKDMYARARAVLPGGNSRTAVFSSPYPIYAASG
                     SGSRVVDLDGTSRIDFLNNSTTLVHGHAHPEIVAAVSEAAARGTCFGLPTESEVLFAEA
                     LCSRNDSFEQARFTSSGTEAVMMAVQASRAHTGKAKIAKIAGAYHGAYDSVAVNNDGSG
                     SLLSHSHTAGMPAEVIANTVVIPFNEPEEAVKILREHVAELACVLVDPVPWRIGLAPMS
                     TEYIAALRAFCDETGVLLVSDEVGSFRIGYGGAMGALGGVADLTVMGKVIGGGMPIGAV
                     AGKAEVMSVFDPSKGKPKLPHSGSYNANPVSMSAGVASLRLLTQEQMKRIGELGEQVRD
                     TMTKTIEANDLDWQVNGLESLFRVLTGTVPGSGASSAQLGHLLFQALLENGVLIGDSGL
                     GCVSTPMIQADIDEFGAAFDSAVTATIDRARAQG"
     aSDomain        12989..13888
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_focI_Aminotran_3.1"
                     /evalue="1.20E-50"
                     /label="focI_Aminotran_3.1"
                     /locus_tag="focI"
                     /protein_end="343"
                     /protein_start="43"
                     /score="164.3"
                     /tool="antismash"
                     /translation="SGSGSRVVDLDGTSRIDFLNNSTTLVHGHAHPEIVAAVSEAAARG
                     TCFGLPTESEVLFAEALCSRNDSFEQARFTSSGTEAVMMAVQASRAHTGKAKIAKIAGA
                     YHGAYDSVAVNNDGSGSLLSHSHTAGMPAEVIANTVVIPFNEPEEAVKILREHVAELAC
                     VLVDPVPWRIGLAPMSTEYIAALRAFCDETGVLLVSDEVGSFRIGYGGAMGALGGVADL
                     TVMGKVIGGGMPIGAVAGKAEVMSVFDPSKGKPKLPHSGSYNANPVSMSAGVASLRLLT
                     QEQMKRIGELGEQVRDTMT"
     gene            14192..14920
                     /gene="foc1"
     CDS             14192..14920
                     /codon_start=1
                     /gene="foc1"
                     /product="SAICAR synthetase"
                     /protein_id="AVW82907.1"
                     /transl_table=11
                     /translation="MTDTVFDAAELAAVVDEREADITGRSKRIWLVRDDLCVVKLIPSL
                     RSFTYDRDELVDETGPLRLDFYEKAAARLSAAGVECAFRTRLGPDSYLADYRPPPPFEV
                     IVKNVATGSTTRKYPGLFQEGEPLPRPVVKFDFRVDPEDQPIGEDYLRVLDLPVEEMRS
                     QALIVNDVLRKWLDPLVLWDFCVIFGFSADGRISLISEVSQDCMRLRHPDGSSLDKDLF
                     RTGASTDELIAGWKRAFDEL"
     gene            14910..15605
                     /gene="foc2"
     CDS             14910..15605
                     /NRPS_PKS="Domain: PKS_KR (6-153). E-value: 1.1e-09. Score:
                     30.2. Matches aSDomain: nrpspksdomains_foc2_PKS_KR.1"
                     /codon_start=1
                     /gene="foc2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     129.7; E-value: 2.2e-39)"
                     /gene_kind="biosynthetic-additional"
                     /product="short chain dehydrognase"
                     /protein_id="AVW82908.1"
                     /transl_table=11
                     /translation="MSSDAPVALITGSNRGSGRAIAEQLEARGYRVFSLNRTVSGQPGE
                     RQCDLADPAALASVTAGVLAEAGRVDVVVANAVDRVLDPIEKMSEEDWDRQLEINLSSV
                     FRLVKHVLPALRRSRGLFVVMGSHAGSHYFEGGAAYSATKAALKALVETLLLEERNNGV
                     RACLLSPGAISNLDGDDAPTKVSVESVGRCVASIVADWPTDLVVGELEFRPAVVPPPPV
                     TGIDRLLHV"
     aSDomain        14928..15368
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_foc2_PKS_KR.1"
                     /evalue="1.10E-09"
                     /label="foc2_PKS_KR.1"
                     /locus_tag="foc2"
                     /protein_end="153"
                     /protein_start="6"
                     /score="30.2"
                     /tool="antismash"
                     /translation="VALITGSNRGSGRAIAEQLEARGYRVFSLNRTVSGQPGERQCDLA
                     DPAALASVTAGVLAEAGRVDVVVANAVDRVLDPIEKMSEEDWDRQLEINLSSVFRLVKH
                     VLPALRRSRGLFVVMGSHAGSHYFEGGAAYSATKAALKALVET"
     gene            15605..16378
                     /gene="foc3"
     CDS             15605..16378
                     /codon_start=1
                     /gene="foc3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 121.6; E-value: 7.3e-37)"
                     /gene_kind="biosynthetic-additional"
                     /product="hydrolase"
                     /protein_id="AVW82909.1"
                     /transl_table=11
                     /translation="MFFVATDLDGTLLTSERVVTARAKNALEELRTAGGVVVLVTARPL
                     RDALEVGAQTGADFLVCSGGAVHYDPARAAVVRSSVLGADRATGLISLLRQTFSGIRLG
                     VDHLDRCDLDPGFDVGSPGAADVHASTPLRHVAEPAVKLIAQSPHLPVDRLAQAVRTLL
                     GSSCAVAVPCSQFIDILPGGVHKALGLDALNPRALRTVAYGDMPSDLPMLRWADLSVAT
                     ANAHPSVLAACDHVTAHHDRDGVAVHLESLLSTGS"
     gene            16380..17252
                     /gene="foc4"
     CDS             16380..17252
                     /codon_start=1
                     /gene="foc4"
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="AVW82910.1"
                     /transl_table=11
                     /translation="MATLALPTGSLHESTLSLFGAAGLTVRRSSSRALRAVIDFDGIDE
                     VVFGKAREIPGFVADGTFDLGLAGTDWIEESGAKIEVVHEIAYSKTTTGTGWRVVLAVP
                     FDHPATTPADLPAGVRVASEYPAISRRYFEEELGLDVRVVHSLGSTEAKVPGLADAVLE
                     VVETGASLRHNNLRELATVRHCGVQLIAGERAWADPAVRAVAEQIATLLRAARAAQENV
                     LLTVVIPVERWQAVRGGLAGRWWLLDGGQDVVAQVTCTRESVAETVIRLTEAGALQVVE
                     TPMSKLVVA"
     gene            complement(17282..18286)
                     /gene="focF"
     CDS             complement(17282..18286)
                     /codon_start=1
                     /gene="focF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 310.9; E-value: 1.1e-94)"
                     /gene_kind="biosynthetic-additional"
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="AVW82911.1"
                     /transl_table=11
                     /translation="MRPTVVLLGALYDPDAEDHIAANAEVVRVDPEDTSALTAALADAH
                     GLIAKYPAEITAEVLAAAPKLIAVLSSGRGTDNIDVPAATEAGVVVANNPGLGGRPVSE
                     HALGLMISVSRDLTAVARHGIEGAWERRLTTHRVELVESTLGIIGIGNVGSNMAHRASR
                     GFGMTVLGYDPYVSAETMAEHGATKVDDLREMLGRCDFVTCHPELNDETEHMFNDETFA
                     AIKKGAYFLNTSRGRVVDTDALVRALRSGHLAGAALDVYEEEPLDPASPLLTMDNVVLS
                     AHVADFTVQTKTALAFSAATKLLGALNGEMPPSALNPQAWQRADLRRKELLGG"
     gene            18424..19647
                     /gene="focU"
     CDS             18424..19647
                     /codon_start=1
                     /gene="focU"
                     /product="phthalate 4,5-dioxygenase"
                     /protein_id="AVW82912.1"
                     /transl_table=11
                     /translation="MATKSMNETLTRVGKGTPMGDLLREYWMPAMRSERVVAGGEPIAV
                     ELLGERYVIFRGDDGTVACFDEACPHRGASLALARNEDCALRCIYHGWKFTTAGETVAT
                     PSEPEDGGRFASKVKLNHHPVVDAGGVIWVWVGGSGREPSPFPRFAFTDLPSSHVFGIV
                     AILECNWMQGLEADIDSAHVSLLHETEAAKGPLKDLLDDRAPRDEIDRTSWGIRYAAVR
                     QLSTGDSLVRVKPMVMPWYTIVPELPNGDRLWHAWVPINDHRTIFWYLWYNEDQPVDPT
                     YFADQFGLDLENMNKDNFREGYSRDNMWGQDRAAMRAGTSFSGISGLAAQDIAVQESMG
                     AIVDRSIENPGKSDTGIVRARHFLLDAVKEKAEGRVPAGLGDDVDYRKIRSANVVVSDG
                     DDWRHLVG"
     gene            19679..20959
                     /gene="focA"
     CDS             19679..20959
                     /codon_start=1
                     /gene="focA"
                     /product="adenylosuccinate synthetase"
                     /protein_id="AVW82913.1"
                     /transl_table=11
                     /translation="MLTAVVGLNWGDEGKGKMVDAITEDVDYVVRYHGGGNAGHTVVVD
                     EGKFSLHNLPSSVFRPDVVSVLGPGMVVDVENFISEVEFVVAHGVSPERILVADTASIC
                     FPFHRDLDAAEEIRLGKASYGSTRMGISPAYGDRVMKKTLLVRDLFDPENLDARLIPVL
                     DWANARLKTIYGATEVELADVREWVGKLADRLRPHVVDVTSLLRRAFDEGKHVLAEGQL
                     GALKDIYFGIYPFTTSSTCLAAHAPVGLGVPWAKLDRVIGVSKAFSSCVGAGPFVSEFD
                     DETADRLREKWGEYGATTNRPRRLGAFDGVATAYGVLMQGADEVALTNLDQLTGIGDLQ
                     ICVAYELDGVRTESFSSDPTVLDRSTPVFETLPGWDSDITGARTYADLPATARAYVDRI
                     EQLLGAPVRYIGVGAHRDALIDRGEDH"
     gene            20959..21522
                     /gene="focH"
     CDS             20959..21522
                     /codon_start=1
                     /gene="focH"
                     /product="AICAR transformylase"
                     /protein_id="AVW82914.1"
                     /transl_table=11
                     /translation="MLAVLGVSDKRGIDVLARGLLDLGWDVVATEGTHRLCVEAGLPVR
                     AVADLAGVPTLLGGRVKTLTVSVMAGILARDTESDLAELSRYDITRVDLVACNYYRLPA
                     DPASFAEFREKVDIGGPAMLRAAAKNCAHVVPLSDPDDYAGVLEQLNAGGVPMEARLAL
                     AAKAFRISADYEQAVAELYAGATA"
     gene            complement(21566..22729)
                     /gene="focQ"
     CDS             complement(21566..22729)
                     /codon_start=1
                     /gene="focQ"
                     /product="amidohydrolase"
                     /protein_id="AVW82915.1"
                     /transl_table=11
                     /translation="MGTLVLTGAATVFSGDPRTPLLDADTVVCRNGVIEAIGRASSHGA
                     RPHGAEVVDLCGGTLAPGLIDSHGHVTFGDYSPRQRTVDYLAGYLQGGITTTVSAGEVH
                     VPGRPRDRAGVKALAVAAQRCFSEYRPGGMRVHAGAVLIEPTLVEEDYAELAEAGVRLA
                     KYGFGAFKDPVDGVDHVRWAREAGLTVMCHAGGASAAGGASLGGKALLALRPDVCGHAN
                     GGPTALPFEEVEALFAETDMALQVVQAGNLKAALRLVEHAVERDELHRVVVGSDTPSGF
                     GVMPLAVLKTVLELTALGGLAPEVAWSLATGTVSDVWGLPEGRIRVGAPADLLGLAAPA
                     GSQADTVSEAMRIGDIPAITVVVSDGVVRAMPGRMTPRPDVPAQLDS"
     gene            22801..23502
                     /gene="focN"
     CDS             22801..23502
                     /codon_start=1
                     /gene="focN"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 55.7; E-value: 9.3e-17)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative HAD superfamily hydrolase"
                     /protein_id="AVW82916.1"
                     /transl_table=11
                     /translation="MSATEPAQVLIFDADDTLWENNVLFERVIDDFLDWIDHPTLDREQ
                     TRKVLDDIEAANAVTHGYGAKMLLQSLHDCFAKLTERPASDEERAKIDDLAGKLVRHEV
                     ELIPGVTDTLDALRGRYRMLLLTKGDLEEQQRKLDASGLAPHFDSIHIVPEKNVDTYLA
                     LIAEQDIEPATAWMIGNSMKSDIGPARAAGMNAVYVPNEHTWVLEFDESVNREDEKVLF
                     IEKFPELLKHF"
     gene            complement(23555..24739)
                     /gene="foc5"
     CDS             complement(23555..24739)
                     /codon_start=1
                     /gene="foc5"
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 83.9; E-value: 1.9e-25)"
                     /gene_kind="transport"
                     /product="MFS transporter"
                     /protein_id="AVW82917.1"
                     /transl_table=11
                     /translation="MTYWSILRRQHVFRVLFGSWVGRLAMAMAAVAIPLALRDAGADYV
                     FIGLVAGSFAISAAIGSPIIGRIVDRVGQVRVLVPTGLLAAAGFVLIAVAPSNHALVLT
                     GAVLAGALTPPLEPCLRVLWPGLVGDDELEKAYAVDSAAQELVFVFGPLVVSLCLAVFA
                     PVSALWAQALLTVVGVAMFATASPARRWTPEKVENRHWLGPLRHRGLMLLLLAPIGMGV
                     AIGTLNVLVVSYAERFEVFGGAPMLLTLNALASLVGVLIYGLIPWKIQPRTRIVYFSVG
                     LLVGYGLLATVPSPLGMAGLMLLTGFFLAPMLAALFGLIGDLAPRGTVTEAFAWLVTLF
                     AAGSSLGAAVVGPVLDRDNLNLAAAHAGVGALFCLLMVSVGYRMFVPAKETALA"
     gene            complement(24768..26210)
                     /gene="focB"
     CDS             complement(24768..26210)
                     /codon_start=1
                     /gene="focB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 104.2; E-value: 1.5e-31)"
                     /gene_kind="biosynthetic-additional"
                     /product="adenylosuccinate lyase"
                     /protein_id="AVW82918.1"
                     /transl_table=11
                     /translation="MKEEMTDHETVPDVLATRYASPALVALWSPRNKVIAERKLWIAVM
                     TAQRELGADIGAQVIADYQSVIEKVDFESITRREVVTLHDVKARLEEFNSLAGHEHAHK
                     GMTSRDLTENVEQMLVRESLELIRLRCVTVLSRLAELAAEHGGTMIASRTHNVPAQVVP
                     LGKRFATAAEEVLVAVERLEDLLRRYPLRGIKGPVGTVQDMLDLFDGDPEKAAALDARI
                     AGFLGFERRFTSVGQVYPRSLDYDVLTALVQIAAGPASLAKTIRLMAGHELASEGFAEG
                     QVGSSAMPHKMNPRNCERINGLMVVLRGYASMAGELAGDQWNEGDVSCSVVRRVALPDA
                     FYAIDGLLQTTLSVLETFFVSPRVIEAELERYLPFLATTKMLVAAVRAGQGRETAHELI
                     KEHALKAAAGLRDGERENTLLATLGADDRFPLDTAQLTALLADRGPFTGVAADQIAEIG
                     KRVTELAGRFPHAVGYASESRL"
     gene            complement(26207..27232)
                     /gene="focT"
     CDS             complement(26207..27232)
                     /codon_start=1
                     /gene="focT"
                     /product="Beta-ribofuranosylaminobenzene 5'-phosphate
                     synthase"
                     /protein_id="AVW82919.1"
                     /transl_table=11
                     /translation="MTTDEQFGPDGWAVEVTAPARLSFTLINLDGESLRRNGIAAMAVR
                     RPGLRARVRPGEGVKITGTEAETTRDLTKGLTKLRELWDGPGVHVDVTRPLPQHSGFGS
                     KTSSLLALGHAYGVLCGRETDLRELSELLGRGRTSGASTGLAAGGGFLVDGGHRNPPDF
                     YAAPEQFLRPSRFAQSVPPPKPVVRLPFPNWPILVLLTNGRHLGGTEELGWFQSVTPIP
                     PAEAARTAQLVFMGLAPAIAEHDYDGFCDAVNEITFRSHFKREQIRFQGKEMIDLLDEG
                     GSEKSVDAIALSVTGPACFAFTRDPGAATRWAQSLKERGLVRDFWFTNACNTGITTSFV
                     P"
     gene            complement(27246..28130)
                     /gene="focC"
     CDS             complement(27246..28130)
                     /codon_start=1
                     /gene="focC"
                     /product="SAICAR synthetase"
                     /protein_id="AVW82920.1"
                     /transl_table=11
                     /translation="MRFSDRYSVFDFGVLGDLIPGKGAASCAMAVHSFALFEKAGVRTH
                     FLEQVADDAIRIQLLDIDTDGSKGPTGSGRTIPLQVIYRLALPRESSVHRRAKQGVLDA
                     STVPPYGEAPWLATPMVEFTTKYEETDRFIGRAEAARVGAVSGDDLLEIAGLAERVAEV
                     LEAHCRSVGLTLVDGKAEFGYDGDRRPILIDHAGTPDENRFYFGGVPVCKELLRYLHPG
                     LREVVQGLIRDGVPRADWPVQPRLKPELVEATSAVYAELAAVWTGGAATGLTTAIEDFK
                     ARCGSDLGDRTGL"
     gene            28386..29252
                     /gene="focX"
     CDS             28386..29252
                     /codon_start=1
                     /gene="focX"
                     /product="6-phosphofructokinase"
                     /protein_id="AVW82921.1"
                     /transl_table=11
                     /translation="MLIGTVALDFLHEGPLGKGLPPATLRWGGVLNNVACALGARDREP
                     VLITADYTGELRGAVAAHLADNDVTWAPASVRSPLPVFHAELVDGSVADMHFLGQEALD
                     SLTPEVLGEQLRAELAGASVLVAATDGEIDTLAWLAEAAGDVPYWLLSADPREVGKLVP
                     RGRRAGLVALNVRELSLWASAELPDDRAVEDAARALAGDEGHVVVTLGEHGSLVVGPDV
                     VARHSLTDALGDIVTVGAGDVHFACLLDAWLQGADWKAALAHAAEHTTAYLNALQCNEQ
                     PYRSLRG"
     gene            29216..29833
                     /gene="focP"
     CDS             29216..29833
                     /codon_start=1
                     /gene="focP"
                     /product="NUDIX hydrolase"
                     /protein_id="AVW82922.1"
                     /transl_table=11
                     /translation="MQRTALPEPARVGRTAHLDSGDMGNTERTAATLLDAYRPADDVEA
                     ADVARLLELVKAEDDPWSRALELHLTSSALVVHPATRRVLLRWHQKMGSWLQIGGHGDP
                     GETDPFDVVLREGREETHLADLRPWPVAELTHVVVVPVPESPKEPAHDHADLRFVLATD
                     TPDEARPEKPTAPLRWLTVPEALDLVEEDNLRETLTRVARLF"
     gene            complement(29839..30309)
                     /gene="Orf+1"
     CDS             complement(29839..30309)
                     /codon_start=1
                     /gene="Orf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160:flavin reductase domain protein FMN-binding
                     (Score: 93.1; E-value: 2.4e-28)"
                     /gene_kind="biosynthetic-additional"
                     /product="flavin reductase"
                     /protein_id="AVW82923.1"
                     /transl_table=11
                     /translation="MIADQLRDALRHQPQAVAIITAAGADGPVGVTVSSFGSASMRPPL
                     VVAWIGATASAWPVLSTVPLFAVHLLGTGQRELADLFARRGADRFGPGTAWKLDDDGVP
                     HLLDAPVRMRCRTEQRVVVGDHVALVGAPVEIQAAEEMPPLVRHQGRWTSVA"
ORIGIN
        1 tcaggccgca gccagccccg cgcggaacca ctcgggcatc agcgagtcgt tgcgcgggaa
       61 ccacttctgc tcggtggcga agttctccgg ggacggtgcc gcctcgaact ccggtgcctc
      121 gtcacggttg tagcggatgg tgaaccggcc gggcgggtcc aggacgtact cgaactcgat
      181 ccaggacccg agcccctcgg cgtacatgcc cttgcgcagc tgctggaact tccgccacac
      241 ctcgggcggg aacgaccagc cgcgcacgga cccgtccggc atcttcacgc ccgtgtcggc
      301 ctcgctgtgc ggcccgatca tcctggcgcg caccacgagc cgcgaccagc cgtgcggcag
      361 ggtcggcagg atctcgccgg tgatctccgc gagcttctgc tgttgttcgg cagggctgag
      421 ctcgggccag gtggccatgg tcgttccccc aggaatcgat gttccgccca gtctacaaag
      481 gagcctggga cagtgcctcg gccagcgcgc ctcccaccgc gtacccggcg gtgagcgcgg
      541 gacccagggt gccgcccgac cccgggtagc ccggcccgaa gacacccgcc gagacgttcc
      601 cgcacgcgta gagccccggc accgcctcgc cggacgcggt cagcacctcg ccggacgtgc
      661 tggtcaccgg tccgcccttg gtgccgagcg ctcccggcac gacctcgacg gcgtggaacg
      721 gcggggtgac gagttcgccc aggcacgggt tgccgggcac gcgggggtcg ccgtagtagc
      781 ggtcgtgcga ggtttcgccg cggtggaagt ccgggtcgct gcccgcgcgg gcgtgcgcgc
      841 tgaaccggtc gacggtcttg gtgagctcgg ccgggtccag gccgagcgcc tccgccagca
      901 gcgccggggt ggcggcactg gtcagccacg acggcgcggg gtcgcgcggc gaggcggggc
      961 cgacgttgta actggtgcgg aacttctcgt cgaagaccag ccacaccggc aggtgcgcgg
     1021 gccggtgccc gtcggcgtcg aagttgaaca gcaccctggt gatgtcgtgg tagttcaccg
     1081 cctcgttcac gaaccggcgg gcgtgccggt cgaccatgat cgaaccgggc aggcagcgct
     1141 cgcccaccag gtgccgcgtc agcggcgcgc cgtcgtactc ctcgggaacg ccgcgcaacg
     1201 cgggcaccca ccaggcctgg ttcatgcgtt ccagcgcggc accggcggac aacgccatcc
     1261 gcagcccgtc cccggtgttc accggcgggc tcaccggcac gaccggggtg tcaccgagga
     1321 acgcccccga cgccgggtcc cactcgaagc cgccgttggc cagcaccacg gcgcgcgcgg
     1381 cgaacgtgcg gccgtcctcg cagcgcacgc ccgacacctt tccttgcgag aacaccagag
     1441 tcgtcgcgcg ggcacccgtc acgaactcca cgcccaacgc gtcgcaggcg gccaccagtg
     1501 cggcggccag agccgcgccc acggtcagca cgccctgctc acgtcgttgt gccagcaggg
     1561 attcgtccgg tccggtgaag cgggagcgat gtcgctcgtc gtaggtcagc ggcgggaact
     1621 gcgggccgcg gcgcaggcgt tcgagcagcc ccgggaaggg cgctgtctcg aacggctcgt
     1681 tgtccacgca gcgtcccacg tccacggcgc cgggccagtc ggagtggtag tcggggcgat
     1741 cgatggggaa gaaccgcgca ccggtgtgct cctccagcca gtcgagcatc tcgggcgcgg
     1801 tgcggacgta gtgctccagc cgctcccgcc cgacggtgcc ctcgacgacc ggttcgaggt
     1861 accgcagcgc gtcctcggcg gagtcgggca gcccggccct cctcatgacg gagctgtccg
     1921 ggatccacag catgccgccg gagaccgcgg tggtgccccc gagcgattcc gagcgttcca
     1981 gcaccacggt ggaaagacca gcggccgccg cccgtgcggc ggcgagcaga cccgcgccac
     2041 cggaacccgc gatgaccacg tcgcgctttt cctcagccac agaattcctt tccctcgata
     2101 accggcggtt cggacggtat aagcggtgtc tgtgtacctg caaggaagcg cacgcacgtg
     2161 cgttatcact cggatggagc atttaatttg tacgctacgt aacgggaatg gagagccccg
     2221 atgttttgtg cgtgtcaagt tgccggtggt gacttgtgct ccatccggtg gtatgacgcg
     2281 caaggccgcg agggttgcgt ccacgcgtgt tgagctgcgt tgatgtgttc tgccggatgg
     2341 cagggcaagg aaaggctctt gcatcggcaa cttccggcaa tcagttttcc aggtgtttgt
     2401 ccgtgttgcg atttccctac cacgccggtt tactggagga cggtcgtggg ggtggccggt
     2461 agaggcgggc tgcgaacagt tgccctgaga accaacaact gtgtgggggt tgacgcatgc
     2521 gctccggcgc tttttcgtcc tcagcaacga ccgtcggtgt tcatttgtcc gaaatggaca
     2581 tgacaggccc ggtgaccgag ctcgtggcga ccgcgctggc tgcggaaacg gcgggagccg
     2641 actacctggt gctgcccgac cgcaccgccg ccgtgccgga cggcgcgagt ccggcgacgg
     2701 ccctcatcgc cgcggcgttc ctggccgcgc ggaccgagga cgtcggcatc gtggtcgccg
     2761 ccgccacgag ctaccacgag ccgtacagcc tggccaggca gacggcgtcc ctcgaccaca
     2821 tcagcgcggg ccgggccggc tggttcgcgg gcagcgcgac cgatcccgcc tccgacgcga
     2881 accaccgccg cgagtgccac gacccggccc gcgatccgca ggccagggcc cgtgagttcg
     2941 tgccgctggt ccgcgcgctg tgggacagct gggaggacgg cgcgttcgtg cacgagaagg
     3001 ccaccggcag gttcgtcgac gcggaccgga tccacaccgt cgaccacgtc ggcgaggcgc
     3061 tcgcggtgcg cggcccgttg aacgtcatcc ggccgccgca aggccaaccg gtggtgttcg
     3121 cgcgcgccac cgacgccgtc gccgaacacg ccgacatcgt gttctccgcc gcgccgcaac
     3181 aagatcacgc tctcgcggtg atcccgttca tcgcggccga cgaggccgcg gcacgggcgc
     3241 tgcacgcggc ggcgggcagt ccggagggcg acgcggacca cgcggtcgtc gtcggcaccc
     3301 cggagcaggt cgccgcgcgg ctggaccatc cgcacgtcct ggtgcgctgc accgcacgcg
     3361 gacagctgac cgcgttcatc gagcaagtgt tgccactgtt gaagaagaag ggccccgccg
     3421 gtacgacgct gcgcgcgcgg ctcggtctcg caccggcacc caaccgcttc gcccgatccg
     3481 aggacgagga gctcatcagc aatgcccgct gagcgcgaac tgcacctggg cctcatgttc
     3541 tgggccaccg gcacgcacca ggcgggctgg cggcatccgg acgcgagccc cgacgcggcc
     3601 tacgacgtcg gcctcatcca ggaggtgagc cgcaccgccg aacgagcgaa gctggacttc
     3661 gtgttcttgg gcgaccgcct ggcgtgcgat ccctcgctgc agcacagcaa tccggcccag
     3721 atctcgcggc tggagccgtt cgccgcggcc accgcgatcg ccgccgccac cacgcacatc
     3781 ggtgtcgtcg tcacggcgaa cccgacgtac tccgacccgt acggcgtcgc ccgcaacctg
     3841 gcctcgctcg accacgtcag cgggggccgc gccgcttgga acctggtgac gggcgcggac
     3901 gccgcggcgg cgttgaacta cagccgcgaa cagcactggg acacgcagaa gcgctacgag
     3961 tgggccgagg agacgctgga gatcgcccgc aagctgtggg acgcgggcga cgagcccatc
     4021 caccaccgca gcgagtactt ccagatcgac gggccgctcg gcctgccccg cccgccgcag
     4081 ggtcaggtcg tgctgctcaa cgcgggcacc tccgaccagg cgcgtgaact gggcgcgcgc
     4141 caggcggaca tggtgttcgc ggggccgcaa ccgacgttgg ccaagcgcaa ggagtactac
     4201 gccgacatca aggcgcgcgc ggccaggtac ggccgtgagg accacgtcac ggtggtgccg
     4261 ggactgaccc cgatcgtcgc gccgacgacg gaggaggccg tcgcgctgca cgacgagctg
     4321 aactcgctga tcctgctgga ccccgaggtc gaggtcggcg acctggtgcg ggcgggcggc
     4381 atcggcgagg gcctcaagcg caacctcacg tcggcgtccg aggcgttcgg cgtcgacctg
     4441 cgcggcaacg acctcgccgc ggtggtgccg gccgaggtgc tggcgaaggt gtccgaggac
     4501 gggaagcgca ggctggccga gatcacgcgg ctgacccggc gcaccgcgga aggcccggac
     4561 cgcatcacct acgcggacct ggtgcacgtc acgccacagc aactctcgca cgtcgtcgtc
     4621 ggcaacccgg aggagatcgc cgacgagatc cagctctggt tcgaggagcg gatggccgac
     4681 ggcttcaaca tctacccggc ctacgtgccc ggttcggtga cggcgttcac cgagctcgtg
     4741 gtgccggtgc tgcagcagcg cggcctgttc cgcaaggact accggggccg cacgctgcgc
     4801 gaccacctcg ggctggaggt gcctgcccgg cgctgagacc cgcccggtcg tccgtccacc
     4861 acacggccga ggccgtggct cgaccatgcg ttcacactgt tgggggagac agttgtctgt
     4921 ccagttgctg cgcgaggaaa gcgcgcacgg atccgcctgg aaaccggcgg accacgtcat
     4981 cgtgccgatc tcgttgctga gagaggccga cacaccgcgg caggcgggca tcgacgccga
     5041 acacgtgcgg gtgctcaccg gcgtcgagga cctgccgccg atcgtggtgc accgccactc
     5101 gatgcgcgtc atcgacgggg tgcaccgcgt tcaggccgcg ctcgcccgcg gtgagggaga
     5161 gatcgcggtc atcttcttcg acggcgacga cgcggcggcg ttcgtgctgg ccgtcgaggc
     5221 caacggcggg cacggcctgc cgttgacgct cgccgaccgc agggccgcgg cgctgcggat
     5281 cgtgcgggcg tacccggagt ggtcggaccg cagggtcgcc tccgtcgcgg gcatctcgcc
     5341 gaagacggtg ggcgcggtca gggcgcggat gtcaagtgag gaaattcctc agcccaccca
     5401 ccgggtcggg ctcgacgggc ggtcccggcc ggtgcacccg cgagccgaac ccgcccgtgc
     5461 caccgaggaa cgggcgccgg tctcgccaca ggcccagcgc cgtccgccgg ggcgggaggc
     5521 gatccacggc gcggtggtct acgcgctgcg ccgcgacccg tcgttgaggt tcagcgagaa
     5581 cgggcggacg ttgctgcgga tgctggacct gcacagcatg tcgccggcgg gctggagcga
     5641 gatcggtgac gcggtgccgg cgcactgcgc gtcgatggtc gcggacctgg cccgcgagtg
     5701 cgcggaggcc tggctgcagt tcgccgacgg cctcgacgag aagtcggcgt gagacggcgg
     5761 ccgcccgcca ccgggaggtg acgggcggcc ggggcgtcac gcgaacctgg tgagccggaa
     5821 ctgttccacc agcgggtgtt cctccccgag cacctcgcgt gcggcgatct cgccgagcac
     5881 cggtgccagc gtgagcccgc tgtgcgtggc gatcacgtac acgccgtcct gtcccggcac
     5941 cgggcccacg atggacatgc cgtcgcgcgg catcggccgc acgcccgtga acacgtgctc
     6001 cacctcggcg tccgccgcgt tcggcagcac ggcggggagc cgttcgagaa cctgttgtgc
     6061 caccgcgctc acgtcaccgt cgccggtgag cgtgcggtcg aggtcgtggc agtgcagcac
     6121 caaccggccg ccggtgtgcg ggcggatgct cagccccggc gcgtggatga tccgggtgac
     6181 cggctcggcg accggggtcg tgcgcaccag caggccgcgc gtgagtcgtt ccggcgcacc
     6241 gggttccagc agcggcaggc cggggagcag gtcggcgttg cccctgcccg cgcagcacag
     6301 caccgcgtcg aacccctccc tcgcctcgtc cagcgacccg gccgtcccga tccgcacctc
     6361 cgcgccggct tcctgtgcct tgtccaggac cgcgggcagc agcacgtgac cgagcacgtg
     6421 cacgtcccgc gggtagaagt ggaccggccc ggccacgtcg gcgagtgcga ggcccggttc
     6481 cagctcacgg gtctgcgcga cggtcagttc ctccaccggg tagccgagtt cgcggtagcc
     6541 gtcggcgatg gcctgctggg cctccgcact cgcctcgtcc cggccccagt gcaggttgcc
     6601 gtgccggaac agccactgcg gtgcctcgcc gacgtccgcg accagccgtt gctgcgccgc
     6661 cagcgcctcg atgctcaggt cgtagtaggc gctgttcttc tcgtcgatgg cgttggccca
     6721 gccgaaactg tgcgcggaca gagtggtgag cggttcttcg cgtgacagca ccgtcacccg
     6781 tgcgcccgcc tcggccagac gcagagcggc gcacgcgccg atcgctcccg cgccgatcac
     6841 caggaccttc atgctttctc cttcgctgac cgcgttgatg cggctccacc ttgggcgcag
     6901 ttccgccgca cacgcaagaa gtccttttta gacaaggctt tgatgctcgc agaggcgcgt
     6961 ggttgactcg ctgtgacttc aagagcacca accgtttcca aggcagtgga gggtcgcttg
     7021 agcacccgca gcgtcctgtt cgtcaacctc aggcggatca agcgtgaggg cttcgagtcg
     7081 ctggtggccg cgcgcaggct cggctaccgg gtcgtgctgc tcggccgcgc cctgccggag
     7141 ttcgccaccg agctggtgga cgagttccac caggtcgaca cctacgacac cgagctggcg
     7201 ctgaagaccg cgcgggagat cgccgccaac aacgacatcg ccggtgttgt caacttcacc
     7261 gagatcgacg tccagctcgt cgcggccatc gccgcggagc tcggcctgcc cggcatgccc
     7321 gtggaggccg ccgtgcgggc gcgcaacaag ctcgcgatga agaacgctct gacgcacatc
     7381 gacggcgtgc tgccgaagtt cgcgcgcgtc ggtgacctgg cggatctgcg cgaggccgtg
     7441 gcgcacatcg ggttcccttg tgtcgtcaag cccaccggcg cctccggctc caagggcatc
     7501 ttcgaactgc acggcgaggc cgacctggaa cccgccatgg cggagctgag ccgcatcgcg
     7561 gacccggcct tcgacgcggt gttccgccag ttcggcgcgg agttcatcgt cgaggagtac
     7621 ctcaccggtg acgagctctc ggtcgagggc ttcgtggcgg ccggtcaggt gcactcgttg
     7681 ctgctgaccg acaaggtcac caccgtgccg ttccacctgg aggtctcgca ccggctgccg
     7741 agcgtgctgc ccgccgccgc gcaggagcag atcatggctc gcgccgcgga gatcgtgctc
     7801 gcgctcgggt tcgacaactg ctcgttccac ctggaagcca agtgggacgg cgaacgcatg
     7861 gggttcatcg aggtcgcggc acggcccgcc ggtgactaca tcgcctcgca cctcgtgaag
     7921 gccgccaccg gcgtcgactt cttcgccaac gtcatccgcg tcgccaccgg cgagccgttg
     7981 cggctcacgc cggaccgcga cctgcacgcg ggcctgcgat tcgtgttcgc cgagcacgag
     8041 ggcacgttcg acggcctcga cggcgtcacg gaactcttcg aggaaccggg ttacgaccac
     8101 gtcttcaccg aggtgacgcc cggcagccgg gtcgcgctgc ccccggcgaa cttcggttcg
     8161 caacgggtcg ccgcggtgtg cgcgcgggcg aacagccgcg agggcctgga cgccctgctc
     8221 gacgcggcgg gcgaccagat caaggtccgc ctcagctagt cccgaggctc tgcgcccccg
     8281 ccggaacccg gcggggtgct tcgccgcgcg ccgaagacca ccagacgggg agggaacgcg
     8341 tgaggctgac actgctgggc tgcggccgga tgggccgcgg cgcgggctac gcactcgccc
     8401 gcgatccgcg cacgacgtcg atcacgctcg tcgaccgtga ccacgaccag gcccgtgcgt
     8461 tggcggactg gctctccggg cgtgcggact gcgaggtccg cgtgggcgac gccggcgcgg
     8521 tcgagggcag tgacgcggtg gcggccgcac tgccgtgggg cgcgacccgc gaggccgtcg
     8581 aactggcggc gaaggcgaag gtgccggtcg cgagcatcac ccgcccgccg gaggccgagt
     8641 cgtccaccgt ggacgaactg gctcgcgccg ccggaatccc cgtgctggtg ccggtgggcc
     8701 tcgaacccgg gctgtccgaa ctcgccgccg ccgacgtggc gcgcaggctc accgctctca
     8761 cgggaggggt gcgcacgctg gaggtgttct gcggcggcgt gcccgccgta ccgcgagagc
     8821 cctggggcta cacggcgttc ttcggcggag agctcgcgaa ccacctgccg atcgcgcaac
     8881 gcacctcgct cgccgtcgaa cacggccagg tcgtcggcca tccccggttc tccggagtgg
     8941 agcaacggca cgtgcccggc gtcggcgaac tggaggccta ccacgacggc atggtcccgt
     9001 ggctcgcgga acacccggcg ctcgcggacg ccgactgcac gcagaagacg ttgcggtggc
     9061 ccggtttcgc gcaggccgtc accggcctcg ccacgctcgg gctgctggac gagtcaccgg
     9121 tcgtggtcga cggtgtggac gtggcgccga aacgcgtcgt cgagcacgtg ctcgcgccgc
     9181 ggttgcgcgc cgggcccgaa gacgaggacg tcgtggtcct ggaggtgtcc gggaccgggc
     9241 tgccggacgc ggacggcaac acggtgagcg tccgggcgtt gctcgtggac cgggccgacc
     9301 cggagaccgg gctcgccgcg atgacccgca cgaccggatt caccctggcc gccgcgaccg
     9361 cgctgctcgg ggagcgcgcg atcgtggaaa cgggctggct tcgtccgcac ctcgcgctga
     9421 cagcggagca cttcgcccgg atcaaggccg atctggccgc gctcggcgtg cggtggagcg
     9481 cggacggaga aggccggcac acctcggaag gcagtgactg atgagtaccg gacacgacgt
     9541 cctggacgtg gtgggcatcg gcatcgggcc ggcgaacctc agcctggccg cgttgctcgc
     9601 gggacaggac agcgggctga aggtcgcgtt cctcgaccgc aagccgcggt tcggctggca
     9661 cgccgggctg atgctgcccg acgtgcagat gcaggtgcac tacctcaagg acctcgtgac
     9721 gccggtcgat ccgacgagcc cgtactcgtt cccggcgttc atggtcgaca ccaagcgctt
     9781 ctaccggctg ctcgtcagcg gccgcagcaa ggtgccgcgc cgcgagttcg agcagtactg
     9841 ccgctgggcc gccgaacgga tccccaacct gcgcttcggc gtcgaggtgc gggacctgac
     9901 gtggaacggc gagctgttcg tcgtccgcac cgaccagggc gacctgctgg cgcgcaacgt
     9961 cgtcagcggc acgggcctgg cgccgcggct gccgtcgttc gcctccgggc acgacccgga
    10021 gcaggtgttc cacgcctcga cgctgctgga cgtgccgagg aagctgcagg gcaggcggat
    10081 cgtggtcgtc ggcggcgggc agagcggcgc cgaggtcgtg caccacctgc tcaccgtgcc
    10141 cgaccggccc gcgtcgatcg tctggggcac ctcgcggacg aacctgctgc cgctggacga
    10201 cagcccgttc gtggacgagc tgttcgtgcc caactacagc cgctacttcc acagcctgcc
    10261 cgccaagcgc cgggtggaac tggtggagga gcagaagatg gcgagcgacg gcatctccgc
    10321 cgggctgctg gaggcgatct accggcgcct ctacgacctg gaggtgctgg agggcgagca
    10381 ccggccgtgc cgcacgttgc tcgggcacgc gctgaccacg gtggagaaga cgccgtccgg
    10441 gttgctgacc cggtggatgc cgaacgcggg cgacgaggtc ggcatcgagg cggacgtcgt
    10501 catctgcgcc accggctacc gccacggact gccgagaccg ttgtacgggc tgcccagcac
    10561 cctgctcgcg gcgatgagcg gggacgacgg cgagatcgcg gtgcggccgg acttcagcct
    10621 cgactgggac gggccgggcg accggcgggt gttcgtgcag aacgccgcgc ggcacagctt
    10681 cggcgtcgcc gacccgaacc tcagcctgct ggcctggcgc agcgcgacga tcgccaacag
    10741 cgtgctcggc ttcgagcgct acccggtcgc cgaggtgagc acggtgctcg actggccgcc
    10801 cggctcgtcc gacgtcgcgc tgacgcactg aacccgacta cggacaggac cgagtgatga
    10861 tcgtcagtga ggtcccgcgc gagctcgccg acctggcacg ggcggacttc gtgcgcagcg
    10921 tcgccccgca gtgggcgcag gccgccgacg cgccgttcaa cgtgcgccgc gtgacgttgc
    10981 ggccgggcga gatcaccgcc gagcacaacc accacgacct ggaggtctgg gtgatgctcg
    11041 acgggtccgg cgaggtgacg tgggacgggc ggcggcgggt gatcaccgcg ggcgacagcg
    11101 tctacctgcc gccgctcgcg ccgcacacgc tgcgcaacct ctccggcgac cggccgctgt
    11161 cgttcttctc gctgtggtgg gagagtctgc ccgcgctcgc cgccgtgcac gccgaacgtc
    11221 aggtggtcga acggcaggga cgcccggtgt tgctgctccc ttccttcccc actccgaacg
    11281 gggagctgca cctcgggcac ctctccggac cgttcctcaa cgcggacgcg tgccggcgcg
    11341 cgttgctggc ggcgggggag cgggcggcgc tgctgctcgg cacggtcggg caccagagcc
    11401 aggtgtcggc ggcggcgcag gcggagggcg tgtcgttcca cgaactggcc gagcgcaaca
    11461 ccgacgccat caccgagggc ctcaccgcgg cgagcgtgga gtgggacgtg ttcgtgcggc
    11521 cctccgagcc cgcctacccc gcgatggcca ccgcggtgtt cgagtcgttg cgcgacaggg
    11581 gcgttctggt ccggcggacc gagccgacga acttctgcga gccgtgcgac cggttcctgc
    11641 tggaggcgtt cgtcgccggc cgttgcccgc actgcggctc cgaccagacc gcgggcatcg
    11701 agtgcgagct gtgcgcgttg ccctaccacg accgcgatct ggtggatccg tcgtgctcga
    11761 cctgcggcac ggcggcggtg caacggccgc tcacccggta cttcctgccg ctggaacccc
    11821 tgcgcgacag gctcaccgac tacctgcgcg gcaccgcgat gcacggcagg ctgcgcgcct
    11881 acgtcgaacg cgtgctcgcg aagcccctgc cggacctgcc ggtcagcatc cccgccgagc
    11941 acggcatccc gatccacgtc gaggacgccg aaggccccgc cgggcaacgg atgtactcgg
    12001 cgttcgagct caccgcgcgg ttcctggtgg cgctggacgg cctcaccggc ggctgggaaa
    12061 gctatgcgcg gcgggagaac ccgcgcacgg tgctgttctt cggcttcgac aacgccttcc
    12121 tgcgcgcctt cgcgttcccg gcggtgctgg gggcgttcac cgacgcgctg gcgctgccgg
    12181 aggcgttggt gtgcaacgac ttctacctgc tcgacggcga gaagttctcc accgggcgca
    12241 agcacgcggt gtggctgcgt gaagcggccg gttcggcgaa cgcggaccag ctgcgcctct
    12301 acctcgccgc cacctcaccg gacgtgcgca gacgtgactt caccgcccag ggctacgcgg
    12361 agttcgtgac cggcgagctg atcggccgct ggcagggcct gctggacgac gtgggcgggc
    12421 ggatcgccga acgcttcggc ggcaccgcac ccgaggccgg cggctggcac gccgaggcgg
    12481 agcggttcta cggccagatc aaggaactcg cgtcggccgc gaccctcgac tacctgcccg
    12541 gccggttcaa gccccgtgcc gtggtggcgg cggtgagcac gctcgttcgg caggcggagg
    12601 acttcgccga ggtcagcgcc gacgccaccc ccggctccgg cctcgcccgc acgtgtgcgg
    12661 cgctggagct gatggcggtg cgcacgctcg ccatggcgat cacgccgctg gcacccgagg
    12721 ccggtggccg gatcgccgcc gcgctgggcg aggacgccat cgcgctcgac gcgacacccc
    12781 gctgggtgcg cagcggtgcc ggcatcaagt tccccaccga tctcttcgac cacgacacga
    12841 ccatcgcgag aggactgaag tgagcgcttc gacctacgag tcggtttcgg ccgcgtccaa
    12901 ggacatgtac gcgcgcgcca gggcggtgct gcccggcggc aacagccgga ccgccgtgtt
    12961 cagctcgccg tacccgatct acgcggcgtc gggcagcggc agccgggtgg tcgacctcga
    13021 cggcacctcc cgcatcgact ttctcaacaa cagcaccacc ctcgtgcacg ggcacgcgca
    13081 cccggagatc gtcgccgcgg tgtcggaggc ggccgcgcgc ggcacgtgct tcggcctgcc
    13141 caccgagtcc gaggtgctct tcgccgaggc gttgtgctcc cgcaacgact ccttcgagca
    13201 ggcgcggttc accagttccg gcaccgaggc cgtgatgatg gcggtgcagg cctcccgtgc
    13261 gcacaccggc aaggcgaaga tcgccaagat cgccggcgcc taccacggcg cctacgactc
    13321 ggtggcggtc aacaacgacg gctccggctc gttgctcagc cacagccaca cggcgggcat
    13381 gccggccgag gtgatcgcca acaccgtggt catcccgttc aacgagcccg aagaggccgt
    13441 caagatcctg cgcgagcacg tcgccgaact ggcgtgcgtg ctggtcgacc cggtgccgtg
    13501 gcggatcggc ctggcgccga tgagcaccga gtacatcgcg gcgctgcggg cgttctgcga
    13561 cgagacgggc gtgctgctgg tgtcggacga ggtcggctcg ttccgcatcg gctacggcgg
    13621 cgcgatgggc gctctcggcg gggtcgccga cctcaccgtg atgggcaagg tgatcggcgg
    13681 cggcatgccg atcggtgccg tcgcgggcaa ggccgaggtc atgtcggtgt tcgacccgag
    13741 caagggcaag ccgaagctgc cgcactccgg ttcctacaac gcgaacccgg tcagcatgtc
    13801 cgccggtgtg gcctcgctgc ggctgctcac gcaggagcag atgaagcgga tcggtgaact
    13861 cggcgagcag gtgcgcgaca cgatgaccaa gaccatcgag gcgaacgacc tcgactggca
    13921 ggtcaacggc ctggagtcgc tgttccgcgt gctcaccggc accgtgccgg ggtccggcgc
    13981 ctcgtcggcg cagctcgggc acctgctgtt ccaggcgttg ctggagaacg gcgtcctcat
    14041 cggcgacagc ggcctcggct gcgtgtccac gccgatgatc caggccgaca tcgacgagtt
    14101 cggcgccgcg ttcgacagcg ccgtcaccgc gacgatcgac agggcccgcg cacagggctg
    14161 atcagcacct tcggcaggaa tggggagagg catgaccgac accgtgttcg acgccgccga
    14221 gctggcggcc gtggtggacg agcgggaagc ggacatcacc gggcgcagca aacgcatctg
    14281 gctggtgcgc gacgacctct gcgtcgtgaa gctgatcccc agcctgcgca gcttcaccta
    14341 cgaccgcgac gagctggtcg acgagacggg gccgctgcgg ctggacttct acgagaaggc
    14401 ggccgcgcgg ctgtccgcgg cgggcgtcga gtgcgcgttc cggacccgtc tcggaccgga
    14461 cagctacctc gcggactacc gcccgccgcc gccgttcgag gtgatcgtca agaacgtggc
    14521 gacgggctcg accacccgca agtaccccgg cctgttccag gaaggcgaac cgctgccgcg
    14581 gccggtggtg aagttcgact tccgggtcga cccggaggac cagccgatcg gcgaggacta
    14641 cctgcgggtg ctggacctgc cggtggagga gatgcgctcg caggcgttga tcgtcaacga
    14701 cgtgctgcgc aagtggctcg acccgttggt gctgtgggac ttctgcgtga tcttcgggtt
    14761 ctccgcagac ggccggatca gcctgatctc cgaggtgtcg caggactgca tgcggttgcg
    14821 ccaccccgac gggtcgtcgc tggacaagga cctgttccgc accggtgcgt ccaccgacga
    14881 gctgatcgcc gggtggaaga gggccttcga tgagctctga cgctccggtc gcgctgatca
    14941 ccgggtcgaa ccggggcagc ggccgcgcca tcgccgagca gctcgaagcg cgtggctacc
    15001 gggtcttctc cctgaaccgc accgtttccg gacagcccgg tgaacggcag tgcgacctcg
    15061 cggacccggc cgcgctggcc tcggtcaccg ccggggtgct ggcggaggcc ggccgggtgg
    15121 acgtggtggt cgccaacgcc gtggaccggg tgctcgaccc gatcgagaag atgtccgagg
    15181 aggactggga ccggcagctg gagatcaacc tgtcgtcggt gttccggctc gtgaagcacg
    15241 tgctgcccgc gttgcggcgg tcccgcgggt tgttcgtggt gatgggcagc cacgcggggt
    15301 cgcactactt cgagggcggt gccgcctact ccgccaccaa ggccgcgctg aaggcgttgg
    15361 tggagacgtt gttgctggag gagcggaaca acggcgtgcg ggcgtgcctg ctctcaccgg
    15421 gcgcgatctc caacctcgac ggggacgacg ccccgaccaa ggtcagcgtc gagtcggtcg
    15481 ggcggtgcgt ggcgagcatc gtcgcggact ggccgacgga cctcgtggtg ggggagctgg
    15541 agttccggcc cgcggtggtg cctccgccgc cggtcaccgg catcgaccgg ctgctgcacg
    15601 tctgatgttc ttcgtcgcca ccgacctcga cggcaccctg ctcaccagcg agcgggtggt
    15661 caccgcacgg gcgaagaacg cgctggagga gctgcggacg gccgggggag tggtcgtgct
    15721 ggtgaccgca cggccgttgc gcgacgcgct ggaggtcggc gcccagaccg gcgcggactt
    15781 cctggtgtgc tctggcgggg ccgtgcacta cgaccccgcc cgggccgccg tggtccggtc
    15841 ctccgtgctg ggcgcggacc gggcgacggg cctgatctcg ttgctgcggc agacgttcag
    15901 cggcatccgg ctcggcgtcg accacctgga ccggtgtgat ctcgatccgg ggttcgacgt
    15961 cggctcgccc ggtgccgccg acgtgcacgc gtccacgccc ttgcggcacg tcgcggaacc
    16021 ggcggtgaag ctgatcgcgc agtccccgca cctgccggtg gaccggctcg cccaggccgt
    16081 ccggacgctg ctcgggtcgt cgtgcgcggt cgcggtgccg tgcagccagt tcatcgacat
    16141 cctgcccggc ggcgtgcaca aggccctcgg gctggacgcg ctgaacccgc gcgcgctgcg
    16201 gacggtcgcg tacggcgaca tgccgtcgga cctgccgatg ctgcgatggg cggacctctc
    16261 cgtcgccacc gcgaacgcgc acccctcggt gctcgcggcc tgcgaccacg tcaccgcgca
    16321 ccacgaccgc gacggcgtcg ccgtccacct ggaaagcctg ctgagcaccg ggagttgaga
    16381 tggccaccct cgcgctgccc accgggtcgc tgcacgagtc caccctgagc ctgttcggcg
    16441 cggcgggact gaccgtgcgg cgctcgtcct cccgcgcgct gcgcgcggtg atcgacttcg
    16501 acggcatcga cgaggtggtg ttcggcaagg ctcgggagat ccccggtttc gtcgccgacg
    16561 gcacgttcga cctcgggctc gccggcaccg actggatcga ggagagcggc gcgaagatcg
    16621 aggtggtgca cgagatcgcg tactcgaaga ccaccaccgg cacgggctgg cgcgtcgtgc
    16681 tcgccgtgcc gttcgaccac cccgccacga ctcccgccga cctgcctgcc ggcgtgcgcg
    16741 tggcgtcgga gtacccggcg atctcccgcc ggtacttcga ggaggaactg ggcctggacg
    16801 tgcgggtcgt gcactccctc ggctcgaccg aggcgaaggt gcccggcctc gcggacgccg
    16861 tgctggaggt cgtggagacc ggtgcgtcgc tgcggcacaa caacctgagg gagctggcca
    16921 ccgtgcggca ctgcggtgtg cagctgatcg cgggggagcg ggcgtgggcg gatccggcgg
    16981 tgcgcgcggt cgccgagcag atcgcgacct tgctgagggc ggcgcgggcg gcgcaggaga
    17041 acgtgctgct gaccgtggtg atcccggtcg aacggtggca ggccgtgcgg ggcgggctgg
    17101 ccgggcgctg gtggctgctc gacggcggcc aggacgtcgt ggcgcaggtg acgtgcacgc
    17161 gggaaagcgt tgcggagacg gtcatccggc tcaccgaggc cggtgccctg caggtggtgg
    17221 agacaccgat gagcaagctg gtcgtggcgt gacgggtgca gggcccgcca cgccacgggc
    17281 atcagccgcc cagcagttcc ttgcgacgca ggtcggcgcg ctgccacgcc tgcgggttca
    17341 gcgcgctggg cggcatctcg ccgttgagcg cccccagcag cttcgtggcg gccgagaacg
    17401 ccagcgccgt cttcgtctgc acggtgaagt cggcgacgtg cgcgctgagc accacgttgt
    17461 ccatcgtcag caacgggctc gccgggtcga gcggctcctc ctcgtacacg tccagcgcgg
    17521 caccggcgag gtgcccgctg cgcaacgccc gaaccagcgc gtcggtgtcg acgacccggc
    17581 cgcgcgaggt gttcaggaag tacgcgcctt tcttgatcgc ggcgaacgtc tcgtcgttga
    17641 acatgtgctc ggtctcgtcg ttgagctccg ggtggcacgt gacgaagtcg cagcgcccca
    17701 gcatctccct gaggtcgtcg accttcgtgg cgccgtgctc ggccatcgtc tccgcgctga
    17761 cgtaggggtc gtagcccagc accgtcatgc cgaagccgcg ggacgcgcgg tgggccatgt
    17821 tgctgcccac gttgccgatc ccgatgatgc cgagcgtgct ctccacgagc tcgacgcggt
    17881 gcgtggtgag cctgcgctcc caggccccct cgatgccgtg ccgcgcgacc gcggtcaggt
    17941 ctcggctcac cgagatcatc aggcccagcg cgtgctcgga caccgggcgg ccgccaagac
    18001 cggggttgtt ggcgaccacc acccccgcct cggtcgcggc gggcacgtcg atgttgtccg
    18061 tgccccgccc gctcgacagc acggcgatca gcttcggcgc cgccgcgagc acctcggcgg
    18121 tgatctccgc cgggtacttc gcgatcagcc cgtgcgcgtc cgcgagtgcc gcggtgagcg
    18181 cggaggtgtc ttccgggtct acgcgcacga cctcggcgtt ggcggcgatg tggtcttccg
    18241 cgtcggggtc gtagagcgcg ccgagaagga cgacggtagg tcgcatgtgc gtggcctccg
    18301 gagaaagttc ttgtggtgca acgctcttca gcgtcgcgaa gcacggcccc gcgcacaagg
    18361 tgttgtgcca gagggatttc tgacatggtt tcgtggagtc cactgcggtg agagaggttt
    18421 tcgatggcca ccaagtccat gaacgagact ctgacccgag tcggcaaggg cacgccgatg
    18481 ggcgatctcc tgcgcgagta ctggatgccg gcgatgcggt ccgagcgcgt cgtggcgggt
    18541 ggcgagccca tcgccgtcga gctgctcggc gagcggtacg tgatcttccg cggcgacgac
    18601 ggcaccgtcg cctgcttcga cgaggcctgc ccgcaccggg gtgcctcgct ggcgttggcg
    18661 cgcaacgagg actgcgcgtt gcgctgcatc taccacggct ggaagttcac caccgccggt
    18721 gagaccgtgg cgacgccgtc cgaacccgag gacggcggcc ggttcgcgtc caaggtgaag
    18781 ctcaaccacc accccgtcgt ggacgcgggc ggtgtgatct gggtgtgggt gggcggcagc
    18841 ggccgtgagc cgagcccgtt cccgcgcttc gccttcaccg acctgccgtc ctcgcacgtc
    18901 ttcggcatcg tggcgatcct ggagtgcaac tggatgcagg gactggaggc ggacatcgac
    18961 tccgcccacg tctcgctgct gcacgagacg gaggccgcga agggcccgtt gaaggacctg
    19021 ctcgacgacc gcgcgccgcg tgacgagatc gaccgcacct cctggggcat ccggtacgcg
    19081 gcggtccgcc aactgtccac cggggacagt ctggtgcggg tcaagccgat ggtcatgccc
    19141 tggtacacca ttgtgccgga gctgccgaac ggtgaccggc tctggcacgc gtgggtgccg
    19201 atcaacgacc accgcaccat cttctggtac ctctggtaca acgaggacca gccggtcgat
    19261 ccgacgtact tcgccgacca gttcgggctc gacctcgaga acatgaacaa ggacaacttc
    19321 cgcgaaggct actcgcggga caacatgtgg ggccaggacc gcgccgcgat gcgcgccggc
    19381 accagtttct cgggcatctc cggcctcgcc gcgcaggaca tcgccgtgca ggagagcatg
    19441 ggcgccatcg tcgaccgctc gatcgagaac ccgggcaaga gcgacaccgg tatcgtccgg
    19501 gcacgtcatt tcctgctgga cgcggtaaaa gagaaggcgg aaggccgcgt tccggccgga
    19561 ctgggcgacg acgtcgacta ccgcaagatc aggtcggcga acgtggtcgt gagcgatggg
    19621 gacgactggc gccacctcgt ggggtgagcg cggtcgcggc gaggggagaa ctgagaacgt
    19681 gctgactgcc gtggtgggcc tcaactgggg cgacgagggc aagggcaaga tggtcgacgc
    19741 catcaccgaa gacgtcgact acgtcgtgag gtatcacgga ggaggcaacg ccgggcacac
    19801 cgtcgtcgtc gacgagggca agttcagcct gcacaacctg cccagcagcg tgttccggcc
    19861 ggacgtggtc agcgtcctcg gcccgggcat ggtggtggac gtcgagaact tcatctccga
    19921 ggtggagttc gtggtcgcgc acggcgtgag ccccgaacgg atcctggtcg ccgacaccgc
    19981 gtcgatctgc ttccccttcc accgcgatct cgacgcggcg gaggagatca ggctcggcaa
    20041 ggcgagctac ggctcgacca ggatgggcat ctcgcccgcc tacggcgacc gggtgatgaa
    20101 gaagacgctg ctggtgcggg acctgttcga tcccgagaac ctcgacgcgc gcctgatccc
    20161 cgtgctggac tgggcgaacg cccggctgaa gacgatctac ggcgccaccg aggtcgaact
    20221 ggccgacgtg cgcgagtggg tcggcaagct cgcggaccgg ctgcgcccgc acgtcgtgga
    20281 cgtgacgtcg ttgctgcgca gggcgttcga cgagggcaag cacgtgctgg ccgagggcca
    20341 gctcggcgcg ttgaaggaca tctacttcgg catctacccg ttcaccacgt cctcgacgtg
    20401 cctcgcggcg cacgccccgg tcgggctcgg ggtgccgtgg gcgaagctgg accgggtgat
    20461 cggcgtgtcc aaggcgttct ccagctgcgt gggagcgggc ccgttcgtca gcgagttcga
    20521 cgacgagacc gcggaccggc tgcgggagaa gtggggcgag tacggcgcga cgacgaaccg
    20581 tccgcgcagg ctcggcgcgt tcgacggggt cgcgaccgcg tacggcgtgc tgatgcaggg
    20641 tgcggacgag gtggcgctga cgaacctcga ccagctcacc gggatcggtg acctgcagat
    20701 ctgcgtggcg tacgagctcg acggcgtgcg caccgagtcg ttcagctccg acccgacggt
    20761 gctggaccgc tccacgccgg tgttcgagac cctgcccggc tgggactccg acatcaccgg
    20821 ggcgcggacg tacgccgatc tccccgccac cgcgcgggct tacgtggacc gcatcgagca
    20881 gctgctcggc gcccccgtgc ggtacatcgg cgtcggcgcc caccgcgacg cgctcatcga
    20941 ccgaggagag gaccactgat gctcgccgtt ctcggcgtca gcgacaaacg cgggatcgac
    21001 gtgctggcca ggggtctgct cgacctgggc tgggacgtcg tggccaccga gggcacgcac
    21061 cggttgtgcg tcgaggccgg tctgccggtg cgggcggtgg ccgacctggc cggcgtgccg
    21121 acgctgctcg gcggccgggt gaagacgctc acggtgtcgg tgatggccgg gatcctggcg
    21181 cgggacaccg aatccgacct ggcggagctg tcccggtacg acatcaccag ggtggacctt
    21241 gtggcgtgca actactaccg gctgcccgcc gacccggcgt cgttcgcgga gttccgggag
    21301 aaggtggaca tcggcggacc cgcgatgctg cgggcggcgg cgaagaactg cgcgcacgtg
    21361 gtgccgttgt ccgacccgga cgactacgcg ggcgtgctgg agcagctgaa cgccggtggg
    21421 gtgccgatgg aggcacggct cgcgttggcg gccaaggcgt tccgcatcag cgcggactac
    21481 gagcaggcgg tcgcggagct gtacgcgggc gccacggcgt agggggttca acgggtcctg
    21541 ccgcgcggca ggacccgttg gcgtttcagg agtccagctg tgcgggcacg tccggccgcg
    21601 gcgtcatccg gcccggcatc gcgcgcacca caccgtcgct cacgaccacc gtgatcgccg
    21661 ggatgtcccc gatccgcatg gcctccgaca cggtgtccgc ctgcgatccc gccggtgccg
    21721 cgagccccag caggtcagcg ggtgcgccga cgcggatccg gccctccggc aggccccaca
    21781 cgtccgacac ggtgcccgtg gcgagtgacc acgccacctc cggcgccagc ccgcccagcg
    21841 cggtcagttc cagcacggtc ttcagcaccg ccagcggcat caccccgaac cccgagggcg
    21901 tgtccgagcc gacgaccacc cggtgcagct catcgcgttc gacggcgtgc tccacgagcc
    21961 gcagcgccgc cttgaggttc ccggcctgca ccacctgcaa cgccatgtcg gtctcggcga
    22021 acagcgcctc cacctcctcg aacggcaacg cggtcggccc gccgttcgcg tgcccgcaca
    22081 cgtccgggcg caacgccagc aaggccttgc cgcccaacga ggccccgcct gccgcgctcg
    22141 ctccgcccgc gtggcacatc accgtcagcc cggcctcccg cgcccaccgc acgtggtcca
    22201 cgccgtccac ggggtccttg aacgcgccga agccgtactt cgcgagccgc accccggcct
    22261 cggccagttc ggcgtagtcc tcctcgacca gggtcggttc gatcagcacc gcgccggcgt
    22321 gcacccgcat cccgccgggc cggtactcgc tgaagcaccg ctgcgccgcc accgcgagcg
    22381 ccttcacccc ggcccggtcg cgcgggcgtc ccggcacgtg cacctcgccc gccgacacgg
    22441 tcgtcgtgat gccgccctgg aggtacccgg cgaggtagtc gaccgtgcgc tggcgcgggc
    22501 tgtagtcacc gaacgtcacg tggccgtgcg agtcgatcag gcccggcgcg agggtgccac
    22561 cgcacaggtc gaccacctcg gcgccgtgcg gacgagcccc gtgagagctc gcgcgcccga
    22621 tcgcctcgat cacgccgttg cggcacacca ccgtgtcggc gtcgagcaga ggtgtgcgcg
    22681 gatcgcctga gaagacggtc gccgcaccgg tcagcacgag ggtgcccatg cgtcctccac
    22741 ttcggttttt cgcttgtgtt caaggaaaag cgctggtcct tgtttgatag catccgccgc
    22801 gtgagtgcga cagagcccgc ccaggtcttg atcttcgacg ccgacgacac gttgtgggag
    22861 aacaacgtcc tcttcgagcg ggtgatcgac gacttcctcg actggatcga ccacccgacg
    22921 ctggaccgcg agcagacccg caaggtgctc gacgacatcg aggccgcgaa cgccgtcacg
    22981 cacggttatg gcgccaagat gttgttgcag agcctgcacg actgcttcgc gaagctcacc
    23041 gagcgccccg cgagcgacga ggaacgcgcc aagatcgacg acctggccgg caagctggtt
    23101 cgccacgagg tcgagctgat cccgggcgtc acggacacgc tcgacgcgtt gcgaggccgc
    23161 taccggatgc tgctgctcac caagggggac ctggaggagc agcagcgcaa gctggacgcc
    23221 tccgggctgg cgccgcactt cgacagcatc cacatcgtgc cggagaagaa cgtcgacacg
    23281 tacctggcgc tgatcgccga acaggacatc gagcccgcga cggcgtggat gatcggcaac
    23341 tcgatgaagt ccgacatcgg cccggcgcgt gccgcgggga tgaacgcggt ctacgtgccg
    23401 aacgagcaca cgtgggtgct ggagttcgac gagtcggtga accgcgagga cgagaaggtg
    23461 ctgttcatcg agaagttccc ggaactgctc aagcacttct gacagacgcg aaaacggccc
    23521 gctcgcctag gtgagcgggc cgttttccgt gtggtcaggc gagagcggtc tccttggccg
    23581 gaacgaacat ccggtagccg acgctcacca tcagcaggca gaacaacgca ccgacgcccg
    23641 cgtgcgccgc cgcgaggttc aggttgtcgc ggtccagcac cggtccgacc acggccgcgc
    23701 cgagcgagct gccggccgcg aagagcgtga ccagccaggc gaacgcctcc gtcaccgtgc
    23761 cgcgcggcgc cagatcaccg atcaggccga acaacgccgc cagcatcggc gcgaggaaga
    23821 agccggtgag gagcatcagc ccggccatcc ccagcggaga cggcacggtc gccagcagcc
    23881 cgtagcccac cagcaggccg accgagaagt acacgatcct ggtcctgggc tggatcttcc
    23941 acgggatcag gccgtagatc agcacgccca ccagcgacgc cagcgcgttc agcgtcagca
    24001 gcatcggcgc gccaccgaac acctcgaacc gctcggcgta gctcaccacc agcacgttca
    24061 gcgtgccgat cgcgacgccc atgccgatcg gggcgagcag cagcaacatc aggccgcggt
    24121 gccgcagcgg gccgagccag tgccggttct ccaccttctc gggcgtccac ctgcgggccg
    24181 gggacgccgt cgcgaacatc gccacgccga cgaccgtgag caacgcctgc gcccacaacg
    24241 cgctgaccgg cgcgaacacc gcgaggcaca gcgacaccac gagcgggccg aagacgaaca
    24301 ccagctcctg cgccgccgag tcgaccgcgt acgccttctc cagttcgtcg tcgccgacca
    24361 gaccgggcca gagcacgcgc aggcacggct ccagcggcgg cgtgagcgca ccggccagga
    24421 ccgcaccggt cagcaccagc gcgtggttcg acggcgccac cgcgatcagc acgaacccgg
    24481 cggcggcgag caggccggtc ggcacgagca cgcgcacctg accgaccctg tcgacgatcc
    24541 ggccgatgat cggagagccg atcgcggcgg agatggcgaa actgcccgcc accagcccga
    24601 tgaacacgta gtcggctccc gcgtcgcgca gggccagcgg aatcgccacg gccgccatgg
    24661 ccatcgcgag cctgccgacc cagctgccga acagcacgcg gaacacgtgc tgcctgcgca
    24721 ggatggacca gtacgtcacc agagcctccc caagtactga ctacgcgtca cagtcgcgac
    24781 tccgaagcgt agccgaccgc gtgcgggaag cgaccggcca gctccgtcac ccgtttgccg
    24841 atctcggcga tctggtcggc cgcgacgccg gtgaacgggc cgcggtcggc gagcagtgcg
    24901 gtgagctgcg cggtgtccag cgggaacctg tcgtcggcgc cgagcgtggc gagcagggtg
    24961 ttctctcgtt cgccgtcacg cagtccggcg gcggccttca gcgcgtgctc cttgatcagc
    25021 tcgtgcgcgg tctcgcggcc ctggcccgcc cgcaccgccg cgacgagcat cttcgtcgtc
    25081 gcgaggaacg gcaggtaccg ctccagttcg gcctcgatca ccctgggcga cacgaagaag
    25141 gtctccagca ccgacagcgt ggtctgcagc aggccgtcga tggcgtagaa cgcgtcgggc
    25201 agcgcgaccc ggcgcaccac cgagcaggac acgtcgccct cgttccactg gtcgcccgcg
    25261 agttcgcctg ccatggaggc gtaaccccgc agcacgacca tcaggccgtt gatccgctcg
    25321 cagttgcgcg ggttcatctt gtgcggcatc gcggacgagc cgacctggcc ctccgcgaac
    25381 ccctccgagg cgagttcgtg cccggccatc aacctgatcg tcttcgcgag cgacgccggt
    25441 cccgccgcga tctgcaccag cgcggtgagc acgtcgtagt ccagcgaccg cgggtagacc
    25501 tggcctacgc tggtgaagcg gcgttcgaag ccgaggaacc cggcgatcct cgcgtccagc
    25561 gcggcggcct tctccggatc accgtcgaac aggtcgagca tgtcctgcac cgtgccgacc
    25621 gggcccttga tgccgcgcaa cggatagcgg cgcagcaggt cctccaggcg ttccacggcg
    25681 acgaggacct cctcggcggc ggtggcgaag cgcttgccga gcggaacgac ctgcgcgggc
    25741 acgttgtggg tgcgcgaggc gatcatcgtg ccgccgtgct ccgcggccag ttcggcgagg
    25801 cgggagagca cggtgacgca ccgcaggcgg atgagctcca ggctctcccg caccagcatc
    25861 tgctcgacgt tctcggtcag gtcgcgcgag gtcatgccct tgtgggcgtg ctcgtggccg
    25921 gccagcgagt tgaactcctc cagccgtgcc ttcacgtcgt gcagcgtcac gacctcgcgc
    25981 cgggtgatcg actcgaagtc gaccttctcg atcaccgact ggtagtcggc gatcacctgg
    26041 gcgccgatgt cggcgcccag ttcgcgttgt gccgtcatca ccgcgatcca cagcttgcgc
    26101 tcggcgatca ccttgttgcg cggcgaccag agcgccacga gcgcgggtga ggcgtaacgg
    26161 gtggcgagca catcgggcac ggtctcgtgg tcggtcatct cttccttcac gggacgaaac
    26221 tggtggtgat gccggtgttg caggcgttgg tgaaccagaa gtcgcgcacg agcccgcgct
    26281 ccttcaggct ctgcgcccag cgcgtcgcgg cgccggggtc gcgggtgaac gcgaagcacg
    26341 cggggccggt cacgctgagc gcgatcgcgt ccacggactt ctcgctgccg ccctcgtcga
    26401 gcaggtcgat catctccttg ccctggaagc ggatctgctc ccgtttgaag tggctgcgga
    26461 aggtgatctc gttgaccgcg tcgcagaagc cgtcgtagtc gtgctcggcg atcgcggggg
    26521 cgagccccat gaacaccagc tgcgcggtgc gggcggcctc ggcgggcggg atcggcgtca
    26581 ccgactggaa ccagccgagt tcctcggtgc cgccgaggtg cctgccgttg gtgagcagca
    26641 cgaggatcgg ccagttcggg aacggcaggc gcaccacggg cttcggtggc ggcacggact
    26701 gcgcgaaccg gctggggcga aggaactgct ccggcgcggc gtagaagtcc ggcgggttgc
    26761 ggtggccgcc gtcgaccagg aacccgccgc ccgcggcgag tccggtgctg gcacccgacg
    26821 tccggccgcg gccgagcagt tcggacagct cgcgcaggtc cgtctcgcgg ccgcacagca
    26881 cgccgtacgc gtggccgagg gcgagcaacg acgacgtctt ggagccgaaa ccgctgtgct
    26941 gcggcaacgg ccgggtgacg tcgacgtgca cgccggggcc gtcccacagc tcgcggagct
    27001 tggtcagccc cttcgtcagg tccctggtgg tctcggcctc cgtgccggtg atcttgacgc
    27061 cctcaccggg gcggaccctg gcgcgcagac ccggcctgcg cacggccatg gcggcgatcc
    27121 cgttgcggcg caacgactcg ccgtcgaggt tgatcagggt gaagctcagt ctggccggtg
    27181 cggtcacctc gacggcccag ccgtccgggc cgaactgctc gtcggtggtc atgatcgtcc
    27241 tccggtcaca ggccggtgcg gtcaccgagg tcggagccgc accgcgcctt gaagtcctcg
    27301 atcgcggtgg tgagtccggt ggccgcccct ccggtccaca cggcggcgag ttccgcgtac
    27361 accgcggagg tcgcctccac cagttctggc ttgagcctgg gttgcaccgg ccagtccgcg
    27421 cgcggcacgc cgtcgcggat cagaccctgg acgacctcgc gcaggccggg gtgcaggtag
    27481 cgcaggagtt ccttgcagac gggcactccg ccgaagtaga agcggttctc gtccggtgtg
    27541 ccggcgtggt cgatgaggat cggccgccgg tcgccgtcgt agccgaactc cgccttgccg
    27601 tccacgagcg tcagcccgac ggagcggcag tgcgcttcga gcacctcggc gacgcgttcg
    27661 gcgaggccgg cgatctccag caggtcgtcg ccgctcaccg ccccgacgcg ggcggcctcg
    27721 gcgcggccga tgaaccggtc ggtctcctcg tacttcgtgg tgaactcgac catcggcgtg
    27781 gccagccagg gagcttctcc gtacggcggc acggtgctcg cgtcgagcac gccctgcttc
    27841 gcgcggcggt gcaccgacga ctcgcgcggc aacgcgagcc ggtagatcac ctgcagtgga
    27901 atggtgcggc ctgacccggt cggccccttg gagccgtcgg tgtcgatgtc gagcagctga
    27961 atgcggatcg cgtcgtcggc gacctgttcc aggaaatgcg tgcggacacc ggctttctcg
    28021 aacaacgcga acgaatgcac ggccatcgcg caggacgcgg cgcccttgcc gggaatcaga
    28081 tcgccgagaa cgccgaagtc gaacaccgaa tagcggtcgc tgaaccgcat gacgccttca
    28141 cccggaacgc cgtcgctggg agcgcgcaga accgtcaagt cctttgtgga ccattgtttc
    28201 acggattccc cctcgggtgc gtgaacggat cggaagctag cacggcgttt ctcggcggcg
    28261 ccaggcttgg aaagcgcact ccggactgat tggctagtgg cgtggctcag agccacatca
    28321 ctaggctccc tgtacagccg gcggaaactg gggaatggtt gatgtaccag catcacgggc
    28381 gaccggtgct gatcggcacg gtcgcactgg acttcctgca cgagggaccc ctgggcaagg
    28441 gcctgccgcc cgcgaccttg cgctggggcg gcgtgctgaa caacgtggcg tgcgcactgg
    28501 gcgcgcgaga ccgcgaaccg gtgctgatca ccgctgatta cacaggtgaa ttgcgcggag
    28561 ccgtcgcggc gcacctggcg gacaacgacg tcacgtgggc gcccgcctcg gttcgttcgc
    28621 cgttaccggt gttccacgcc gaactggtcg acggttcggt ggcggacatg cacttcctcg
    28681 gtcaggaggc gctcgactcg ctcacgccgg aggtgctggg ggagcagctg cgggcggagc
    28741 tggccggggc gagcgtgctg gtggcggcga ccgacggtga gatcgacacg ctggcgtggc
    28801 tcgcggaggc cgccggcgat gtgccgtact ggctgctctc ggccgatccg cgcgaggtgg
    28861 gcaagctggt cccgcgcggc cgtcgtgccg gtctggtggc gttgaacgtg cgtgagctgt
    28921 cgctgtgggc ctcggccgag ttgcccgacg accgcgcggt cgaggacgcg gcgcgtgcgt
    28981 tggcgggcga cgaggggcac gtggtcgtga cgctcggcga gcacggctcg ttggtggtgg
    29041 ggccggacgt cgtggcgcgg cattcgctca ccgacgcgtt gggggacatc gtcaccgtgg
    29101 gcgccggcga cgtgcacttc gcgtgcctgc tcgacgcgtg gctgcagggc gcggactgga
    29161 aggcggcgct ggcgcacgcg gccgagcaca ccaccgcgta cctgaacgcg ttgcagtgca
    29221 acgaacagcc ctaccggagc ctgcgcgggt aggccggacg gctcatctag actcgggcga
    29281 catggggaac accgagcgca ccgccgccac gctgctggac gcctaccggc ccgccgacga
    29341 cgtcgaggca gccgacgtgg cccggctcct cgagctggtc aaggccgagg acgacccgtg
    29401 gtcgcgtgcc ctggagctgc acctcacgtc gtcggcgctg gtcgtgcacc cggcgacgcg
    29461 gcgggtgctg ctgcgctggc accagaagat gggcagctgg ctgcagatcg gcggccacgg
    29521 cgaccccggc gagaccgacc cgttcgacgt ggtgctgcgc gagggccggg aggagaccca
    29581 cctcgccgac ctgcgcccgt ggccggtggc ggagctgacg cacgtggtcg tcgtgccggt
    29641 gcccgagtcg cccaaggagc ccgcgcacga ccacgccgac ctgcggttcg tgctcgccac
    29701 cgacaccccg gacgaggcgc ggccggagaa gccgaccgcg ccgctgcgct ggctgaccgt
    29761 tcccgaggcg ctggacctgg tcgaggagga caacctgcgg gagacgctga cgcgggtggc
    29821 ccgcctgttc tgacgggctc aggccaccga cgtccaccgc ccctgatgcc gcaccagggg
    29881 cggcatctcc tcggcggcct ggatctccac cggggcgccc acgagggcca cgtggtcgcc
    29941 gaccaccacc cgttgctcgg tccggcagcg catccggacc ggtgcgtcga gcaggtgcgg
    30001 caccccgtcg tcgtcgagct tccacgccgt tccggggccg aagcggtcgg ctcccctgcg
    30061 cgcgaacagg tccgcgagtt cgcgctggcc ggttccgagc aggtgcaccg cgaacagcgg
    30121 caccgtgctc agcaccggcc acgccgacgc cgtcgccccg atccacgcca ccaccagcgg
    30181 cggccgcatg ctggccgacc cgaaggagct gacggtcacg ccgaccggtc cgtccgcgcc
    30241 ggcggcggtg atgatcgcga cggcctgcgg ctggtgccgc agcgcgtccc tgagctgatc
    30301 cgcgatcac
//
