BGC0002040: coformycin biosynthetic gene cluster from Streptomyces kaniharaensis
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Location: 1 - 39,112 nt. (total: 39,112 nt).
This entry is originally from NCBI GenBank KY705052.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002040
Short description coformycin biosynthetic gene cluster from Streptomyces kaniharaensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
KY705052.1
via
Compounds
  • coformycin
  • formycin A
Species Streptomyces kaniharaensis [taxonomy]
References
Chemical products information
coformycin Evidence:
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Chemical database entries
NPAtlas
PubCHEM
formycin A Evidence:
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Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AVW82929.1
  • orf-1
 1 - 1020 (+) putative quercetin 2,3-dioxygenase PA1205
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    • AVW82930.1
    • cof1
    		 1047 - 1934 (-) phosphofructokinase
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      • AVW82931.1
      • cof2
      		 1931 - 4726 (-) oxidoreductase
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        • AVW82932.1
        • cof3
        		 4752 - 5753 (-) SAICAR synthetase
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          • AVW82933.1
          • cof4
          		 5785 - 6342 (-) FMN reductase (NADPH)
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            • AVW82934.1
            • cof5
            		 6445 - 7617 (-) phthalate 4,5-dioxygenase
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              • AVW82935.1
              • cof6
              		 8007 - 9032 (+) beta-ribofuranosylaminobenzene 5'-phosphate synthase
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                • AVW82936.1
                • cof7
                		 9103 - 10527 (+) adenylosuccinate lyase
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                  • AVW82937.1
                  • cof8
                  		 10600 - 12189 (+) fumarate reductase/succinate dehydrogenase
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                    • AVW82938.1
                    • cof9
                    		 12186 - 13310 (+) glycine/D-amino acid oxidase
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                      • AVW82939.1
                      • cof10
                      		 13336 - 14526 (+) amidohydrolase
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                        • AVW82940.1
                        • cof11
                        		 14624 - 15187 (+) NUDIX hydrolase
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                          • AVW82941.1
                          • cof12
                          		 15245 - 17455 (-) S9 family peptidase
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                            • AVW82942.1
                            • cof13
                            		 17930 - 19240 (+) phosphoribosylglycinamide synthetase
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                              • AVW82943.1
                              • cof14
                              		 19273 - 20427 (+) saccharopine dehydrogenase
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                                • AVW82944.1
                                • cof15
                                		 20468 - 21790 (+) L-lysine N6-monooxygenase
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                                  • AVW82945.1
                                  • cof16
                                  		 21847 - 23880 (+) methionine-tRNA ligase
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                                    • AVW82946.1
                                    • cof17
                                    		 23971 - 25242 (+) aminotransferase
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                                      • AVW82947.1
                                      • cof18
                                      		 25266 - 25958 (+) RNA polymerase, sigma-24 subunit, RpoE, ECF subfamily
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                                        • AVW82948.1
                                        • cof19
                                        		 26005 - 27006 (+) phosphoglycerate dehydrogenase
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                                          • AVW82949.1
                                          • cof20
                                          		 27042 - 28313 (+) adenylosuccinate synthetase
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                                            • AVW82950.1
                                            • cof21
                                            		 28341 - 28931 (+) AICAR transformylase
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                                              • AVW82951.1
                                              • cof22
                                              		 28928 - 29956 (+) putative monooxygenase
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                                                • AVW82952.1
                                                • cof23
                                                		 29991 - 31310 (+) putative monooxygenase
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                                                  • AVW82953.1
                                                  • cof24
                                                  		 31368 - 32582 (-) MFS transporter
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                                                    • AVW82954.1
                                                    • cof25
                                                    		 32619 - 33626 (-) metal dependent phosphohydrolase
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                                                      • AVW82955.1
                                                      • cof26
                                                      		 33835 - 35193 (-) GntR family transcriptional regulator
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                                                        • AVW82956.1
                                                        • cof27
                                                        		 35421 - 36140 (+) SAICAR synthetase
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                                                          • AVW82957.1
                                                          • cof28
                                                          		 36133 - 36834 (+) short chain dehydrognase
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                                                            • AVW82958.1
                                                            • cof29
                                                            		 36869 - 37291 (+) hypothetical protein
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                                                              • AVW82959.1
                                                              • cof30
                                                              		 37284 - 38078 (+) hydrolase
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                                                                • AVW82960.1
                                                                • orf1
                                                                		 38378 - 39112 (-) Golgi apparatus membrane protein TVP18
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                                                                  Biosynthesis information
                                                                  Annotation changelog

                                                                  Entry version: next

                                                                  Date
                                                                  Changes
                                                                  Submitters
                                                                  Reviewers
                                                                  2024-08-10
                                                                  MIBiG v4 annotathon
                                                                  • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                  Entry version: 2

                                                                  Date
                                                                  Changes
                                                                  Submitters
                                                                  Reviewers
                                                                  2022-10-07
                                                                  Changed chemical structures for compounds: coformycin.
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                  2022-10-07
                                                                  Added NPAtlas links to compounds: coformycin.
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                  Entry version: 1

                                                                  Date
                                                                  Changes
                                                                  Submitters
                                                                  Reviewers
                                                                  2022-09-15
                                                                  Entry added
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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