BGC0002042: anthelvencin A biosynthetic gene cluster from Streptomyces venezuelae
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Location: 1,540 - 27,652 nt. (total: 26,113 nt).
This entry is originally from NCBI GenBank MK483114.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002042
Short description anthelvencin A biosynthetic gene cluster from Streptomyces venezuelae
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: MK483114.1
Compounds
  • anthelvencin A
  • anthelvencin B
  • anthelvencin C
Species Streptomyces venezuelae [taxonomy]
References
Chemical products information
anthelvencin A
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C19H25N9O3
anthelvencin B
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C18H23N9O3
anthelvencin C
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C20H27N9O3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QEG98935.1
  • ant22
 1540 - 3081 (-) ant22
  • Activation / processing
Sequence-based prediction
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  • QEG98936.1
  • ant21
 3065 - 4975 (-) ant21
  • Transport
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  • QEG98937.1
  • ant20
 4975 - 6813 (-) ant20
  • Transport
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  • QEG98938.1
  • ant1
 7473 - 8099 (+) ant1
  • Regulation
Sequence-based prediction
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  • QEG98939.1
  • ant2
 8509 - 9930 (+) ant2
  • Scaffold biosynthesis
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  • QEG98940.1
  • ant3
 10427 - 11806 (+) ant3
  • Precursor biosynthesis
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  • QEG98941.1
  • ant4
 11803 - 12348 (+) ant4
  • Precursor biosynthesis
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  • QEG98942.1
  • ant5
 12345 - 13295 (+) ant5
  • Precursor biosynthesis
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  • QEG98943.1
  • ant6
 13297 - 14076 (+) ant6
  • Precursor biosynthesis
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  • QEG98956.1
  • ant8
 14126 - 15430 (+) ant8
  • Precursor biosynthesis
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  • QEG98944.1
 15423 - 16415 (+) ant9
  • Precursor biosynthesis
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  • QEG98945.1
  • ant10
 16412 - 17494 (+) ant10
  • Precursor biosynthesis
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  • QEG98946.1
  • ant11
 17491 - 18255 (+) ant11
  • Precursor biosynthesis
Sequence-based prediction
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  • QEG98947.1
  • ant12
 18252 - 19403 (+) ant12
  • Precursor biosynthesis
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  • QEG98948.1
  • ant13
 19385 - 21286 (+) ant13
  • Precursor biosynthesis
Sequence-based prediction
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  • QEG98949.1
  • ant14
 21283 - 22185 (+) ant14
  • Scaffold biosynthesis
Sequence-based prediction
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  • QEG98950.1
  • ant15
 22197 - 23003 (+) ant15
  • Tailoring (Methylation)
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  • QEG98951.1
  • ant16
 23000 - 24334 (+) ant16
  • Scaffold biosynthesis
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  • QEG98952.1
  • ant17
 24331 - 25377 (+) ant17
  • Precursor biosynthesis
Sequence-based prediction
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  • QEG98953.1
  • ant19
 25467 - 25808 (+) ant19
  • Scaffold biosynthesis
Sequence-based prediction
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  • QEG98954.1
  • ant23
 25893 - 27236 (-) ant23
  • Scaffold biosynthesis
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  • QEG98955.1
  • ant24
 27275 - 27652 (-) ant24
  • Precursor biosynthesis
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
ant22
Module ?
not strictly speaking A domain

Specificity: 4-acetamidopyrrole-2-carboxylic acid
Evidence for specificity:
  • Sequence-based prediction
ant2
Module ?
Condensation domain type: LCL
ant16
Module ?
Condensation domain type: LCL
Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: P34OM6JOCMMIEQMA65E4OI3N, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
  • Corrected NRP module activity
  • Corrected gene identifiers
  • Added version to NCBI accession
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
  • Changed chemical structures for compounds: anthelvencin C.
  • Added NPAtlas links to compounds: anthelvencin C.
Detailed domain annotation
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