LOCUS       BGC0002042             26113 bp    DNA     linear   BCT 28-AUG-2019
DEFINITION  Streptomyces venezuelae culture ATCC:14583 anthelvencin biosynthetic
            gene cluster, complete sequence.
ACCESSION   BGC0002042
VERSION     BGC0002042
KEYWORDS    .
SOURCE      Streptomyces venezuelae
  ORGANISM  Streptomyces venezuelae
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 06:14:52
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1539
            Orig. end    :: 27652
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1542)
                     /NRPS_PKS="Domain: AMP-binding (24-416). E-value: 3.1e-89.
                     Score: 291.2. Matches aSDomain:
                     nrpspksdomains_ant22_AMP-binding.1"
                     /codon_start=1
                     /gene="ant22"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     354.5; E-value: 1.3e-107)"
                     /gene_kind="biosynthetic-additional"
                     /note="Acyl-CoA synthetase"
                     /product="ant22"
                     /protein_id="QEG98935.1"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-92, bitscore:
                     299.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATASEHQADGPGRPGPTTLRELLDSAARARPRAVAVRGEDAVLT
                     YGELHERVRATARRFEALGVTGRGAAGLLLENTPDSVVALLAAARLGVRLVPLEPGTTR
                     TQLGSVREALGPLSVMGHTARLAALEGAEGPDPLDCAFIPIEDPGGDTPSRVPEGDAAA
                     MPDAPFLHQYTSGSTGEPKVAVHTQRNLVNGGDIYARSYGITEDDRILAAVPLLHSFGL
                     VAGLVTALRAGAELVLLGRFTPARLLRALEEHACTVLVAAPMAYDLTTRAAGASPSVPR
                     ALRLCLSSGAALPPAVARRAKERLGLDIQQVYGCTEAGVIAARRPEDGSAADLGVGRPM
                     PGVRIRVVDERGDEVARGEEGALLVRTPAMFTHYLGHADATREAFADGWYRTGDVARVG
                     PEGHLHLVGRKDSFINVGGKKVNPLEVEQALLAHPSVVEAVVWGETTDDGGERVRASVV
                     ARPPLPATELTSHCRARLLPHQVPAEVDFVASLPKSSMGKIRRAAVRTAAAVRRS"
     subregion       1..26113
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="NRP"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..26113
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1542)
                     /gene="ant22"
     aSDomain        complement(295..1470)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ant22_AMP-binding.1"
                     /evalue="3.10E-89"
                     /label="ant22_AMP-binding.1"
                     /locus_tag="ant22"
                     /protein_end="416"
                     /protein_start="24"
                     /score="291.2"
                     /tool="antismash"
                     /translation="DSAARARPRAVAVRGEDAVLTYGELHERVRATARRFEALGVTGRG
                     AAGLLLENTPDSVVALLAAARLGVRLVPLEPGTTRTQLGSVREALGPLSVMGHTARLAA
                     LEGAEGPDPLDCAFIPIEDPGGDTPSRVPEGDAAAMPDAPFLHQYTSGSTGEPKVAVHT
                     QRNLVNGGDIYARSYGITEDDRILAAVPLLHSFGLVAGLVTALRAGAELVLLGRFTPAR
                     LLRALEEHACTVLVAAPMAYDLTTRAAGASPSVPRALRLCLSSGAALPPAVARRAKERL
                     GLDIQQVYGCTEAGVIAARRPEDGSAADLGVGRPMPGVRIRVVDERGDEVARGEEGALL
                     VRTPAMFTHYLGHADATREAFADGWYRTGDVARVGPEGHLHLVGRKDSFINV"
     CDS_motif       complement(982..1029)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ant22_0002"
                     /evalue="7.20E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ant22"
                     /protein_end="187"
                     /protein_start="171"
                     /score="15.6"
                     /tool="antismash"
                     /translation="QYTSGSTGEPKVAVHT"
     CDS_motif       complement(1432..1470)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ant22_0001"
                     /evalue="4.60E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="ant22"
                     /protein_end="37"
                     /protein_start="24"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="DSAARARPRAVAV"
     gene            complement(1526..3436)
                     /gene="ant21"
     CDS             complement(1526..3436)
                     /codon_start=1
                     /gene="ant21"
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     263.2; E-value: 3e-80)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 367; E-value:
                     2.9e-111)"
                     /gene_kind="transport"
                     /note="ABC transporter, ATP-binding protein"
                     /product="ant21"
                     /protein_id="QEG98936.1"
                     /transl_table=11
                     /translation="MAHLLEGIDPDDYDRRYGDRELARRIAPYFRGKGRAVVFVTLAVI
                     IAATAGSAVPLLLARTVDSALKDDGDGRLAWLVAAMLVAGIAAWLLNLLQERAAGTMAG
                     DVVLKLRERAFAAAMRQDMAFHDAHPTGVVVSRVTNDTQAFATLITLMLSLLGQVLMIV
                     ILLTALFVINVPLALVTAFVAAVIVAVSLAFRRAARSASLRQQEALAEVNGYVQETLRG
                     IAVARNHSHQQSAQTGLDEVNHRWFKASVRLNRLFSGIFPLLISLTGLGTVAVVLVGGH
                     GVDSGSVSAGEWVLFLEALALFWSPLTSIASFWSQLQQGLAAGERVFALVDRESTVRQL
                     DRVPVPRLRGEITLRDVHFGYDDEHPVLNGVSLDIPAGRTVALVGHTGAGKSSVVRLIM
                     RAYEFQKGSIEVDGLDVRSLDLDQYRRCLGVVTQTPFLFSGTVADNIARGRPGAGRDEI
                     EAAARAVAGGDWLEQLAQGLDTPTDEGGRNLSTGQRQIVALARVFLQDAPVLILDEATA
                     SIDPLTEAQIQEGLEALAADRTTIVVAHRLPTVRKADTIVVVDEGRIIEEGDHATLLAR
                     GGAYRRLYDRYFRHQRPDEDPAEPVEPRPVALTPFAGAVASANGHADQDGEESVVDGHR
                     V"
     gene            complement(3436..5274)
                     /gene="ant20"
     CDS             complement(3436..5274)
                     /codon_start=1
                     /gene="ant20"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 359.1; E-value:
                     7.4e-109)"
                     /gene_kind="transport"
                     /note="ABC transporter, trans-membrane protein"
                     /product="ant20"
                     /protein_id="QEG98937.1"
                     /transl_table=11
                     /translation="MTAETMAGATAADDTDDDADRRSVPRWLLAQMRPFRPYIALFLLG
                     SLAWQSLTAAIPLVTGLAFDAVLDQDDGSPDFGTFHAIAAGLFALVVVRALGGIMSTYS
                     LESFASGLERNARAQVFASLLRKSQGYFNRRRVGDLSARATGDAESLNLMVSPGFDLAV
                     DLALNILMPIVFIALVDPRLLVSPVVFVLLFAVALAEHGRRLEPVSDTARERFGDMTAQ
                     ASESIAGIEVVGSTGGADQERARFTDLARAYRDASVRQIRTQALALSPLLLTLATVGAL
                     VHSVILLRDDSLSIGELVAVLGLMGTLRAPTQLASFSLGLIYLGMAGAQRIKEVVDDPE
                     GEDERGGRHTGPVVGEVAMENVTFGYEPGKPVLRDVSFRVAPGTTVAIVGATGSGKSTL
                     LHLLNRTYIPDEGRVLVDGVPTTDWDIGALRSRTSVIEQDVMLFSRSIAENLSLGSDNG
                     TDRSRMEDAARIAQAHDFITAAENGYDTVIGERGVTLSGGQRQRLAIARALIADPRILA
                     VDDATSAVDSATEYEVQRAMRQASDGRTTFLVTPRLSRIRAADHILVLDAGRIVDQGSH
                     EQLLRDCSLYRRIFAPYLSTPAPGGPDSAGAKEESH"
     gene            5934..6560
                     /gene="ant1"
     CDS             5934..6560
                     /codon_start=1
                     /gene="ant1"
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 79.8; E-value:
                     2.8e-24)"
                     /gene_kind="regulatory"
                     /note="two-component response regulator"
                     /product="ant1"
                     /protein_id="QEG98938.1"
                     /transl_table=11
                     /translation="MVTTLVRNGFLQLGLRAALSTAPLVRDVRHCGDWGEVEETLRNNQ
                     VDVLFLHEKDYSPDRGVLVDARRHRPKILLLLTTTEVPEEILAGPSVPDGFLVENELTA
                     TAVEDALQGIVAGEVPMPTSVTRALLRRVREPEQQRRRRVGNLTGRENEVLPLLAEGLS
                     NKQIARRLGISSHGVKRIVASLLLKLGAPNRTAAVVTAIQNGLIT"
     gene            6970..8391
                     /gene="ant2"
     CDS             6970..8391
                     /NRPS_PKS="Domain: Condensation_LCL (18-299). E-value:
                     2.4e-34. Score: 110.6. Matches aSDomain:
                     nrpspksdomains_ant2_Condensation_LCL.1"
                     /codon_start=1
                     /gene="ant2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     185.5; E-value: 3.4e-56)"
                     /gene_kind="biosynthetic-additional"
                     /note="Nonribosomal peptide synthetase condensation domain"
                     /product="ant2"
                     /protein_id="QEG98939.1"
                     /sec_met_domain="Condensation (E-value: 1e-30, bitscore:
                     97.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEFVRHRIPFAGRRSVTAPATCAQRHLWNLMQRQLPDASFYDVC
                     YWVALPGHGTAQDLLDVCGELVVRHESLRTAFHRDADGSLVQHVVDAAEFEAEVWTLAP
                     HEDPDGVRRAWERRMRHTPFDPARAPLIRFMVTVVDGVPVLAAFCVSHLSVDLTSVRLL
                     ADELTRLLDARAAGRPLPPAAPARQPVEQAQLEQSPRGRALQARSRTYWQRQLDRAPAT
                     LFPDRGGPAAPVRYSAGMSSRAVALAVPVLARRWRVSTSVVLLTVVARLLGRRAGSPSC
                     TLRLLTANRSDPDVRGTVANLHTEVPVTIALDGDRAEDVARRALAACTAAYANGLYDPD
                     DIARLIADARGPGVPVDLSYCFNDIREEQPLPDTADGDGAVSGESPRAAMADTVVAPDE
                     FEEGETFFVVVDDEVPGWIRVVLNADHRALTPSEVHAFLHDIERLLVEYVEDAGGEHGP
                     AAAVGGAGRGAATES"
     aSDomain        7024..7866
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ant2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.40E-34"
                     /label="ant2_Condensation_LCL.1"
                     /locus_tag="ant2"
                     /protein_end="299"
                     /protein_start="18"
                     /score="110.6"
                     /tool="antismash"
                     /translation="APATCAQRHLWNLMQRQLPDASFYDVCYWVALPGHGTAQDLLDVC
                     GELVVRHESLRTAFHRDADGSLVQHVVDAAEFEAEVWTLAPHEDPDGVRRAWERRMRHT
                     PFDPARAPLIRFMVTVVDGVPVLAAFCVSHLSVDLTSVRLLADELTRLLDARAAGRPLP
                     PAAPARQPVEQAQLEQSPRGRALQARSRTYWQRQLDRAPATLFPDRGGPAAPVRYSAGM
                     SSRAVALAVPVLARRWRVSTSVVLLTVVARLLGRRAGSPSCTLRLLTANRSDPDVRGTV
                     "
     CDS_motif       7153..7203
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ant2_0001"
                     /evalue="1.90E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="ant2"
                     /protein_end="78"
                     /protein_start="61"
                     /score="17.1"
                     /tool="antismash"
                     /translation="VCGELVVRHESLRTAFH"
     gene            8888..10267
                     /gene="ant3"
     CDS             8888..10267
                     /codon_start=1
                     /gene="ant3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 430.8; E-value:
                     8.2e-131)"
                     /gene_kind="biosynthetic-additional"
                     /note="4-acetamidopyrrole-2-carboxaldehyde dehydrogenase"
                     /product="ant3"
                     /protein_id="QEG98940.1"
                     /transl_table=11
                     /translation="MENPALGKVFAETPGCTPERLDDVLDDAARAFPGWAATPLAERRE
                     WLHSCHRALLGAVDPMAELLTREQGKPLKHARAEVRLAADWFARTAELGLTQERLVDET
                     DARIDLERVPHGVVAAIAPSNYPVLLAVCKIAPALLAGNTVVLKPSPDTPLSSLMMGRI
                     LGDVLPAGTFAVVDGDVELGARLTVHPAVRLVSFTGSVGAGRAIARQAAADLKRVVLEL
                     GGNDPAVVLPGTDVLSVAPDLFAAAMTNSGQFCAAVKRVYAPRATYRRLAEALAEKART
                     AIVGDGLDPATEYGPLVSRAQLHHVAGLVDDAVAAGADVLAGGGPLDGPGHFYPPTVVT
                     DLPPGSRLEEEEQFGPVIPVIPYDDVDQVFAQVNASTYGLGCSLWGDEERARELAGRPQ
                     CGTVWINTHGALRHDVPFGGHRHSGIGVEYGAWGLNEYTQLKVHHSALRLRPRQADRET
                     S"
     gene            10264..10809
                     /gene="ant4"
     CDS             10264..10809
                     /codon_start=1
                     /gene="ant4"
                     /note="CMP hydrolase"
                     /product="ant4"
                     /protein_id="QEG98941.1"
                     /transl_table=11
                     /translation="MSDSTVVRVDGTDGIDLTGVKVFVGGPIQHAIRDDGFHQPLQHAI
                     GDIIEAVTAAHGTVFSAHVAEKFGVDTPLFSPDQVSVRDIGWMRRCDVFVPVLPVDAAG
                     ELMRTDGTHVELGWASALDKPIVVVTPMPMAANASHLLRGLPSVADVTVFDLEEARANP
                     VELLRLLEKLGQEAVMAP"
     gene            10806..11756
                     /gene="ant5"
     CDS             10806..11756
                     /codon_start=1
                     /gene="ant5"
                     /note="Cytosine reductase"
                     /product="ant5"
                     /protein_id="QEG98942.1"
                     /transl_table=11
                     /translation="MTAAEDGANGAEAPGAAATAAPVEILGLRLKSPVVVGSGLLTDQE
                     RNIRRLLDGGAGAVVTKTIHPNPGPPGNERLLRLPTGMLNSTTYSRRSVDDWCAMLRRF
                     ADDDLPVITSVHADSPAELADLAERVTEAGSTALELGISCLNEEDGGLEDTPERVAAYT
                     EAVRSRTPVPISVKLAIGERVRERVDAATASGADALTLSDTISGLAVDADTGEVRLGGA
                     FGYSGPGIKPLVLAEIYGLRRDGLTVPVMASGGVNDAVDVAEYLSVGADAVQVYTVLHK
                     NMHATLRAIRQGFDDWLASHGGTVADLVGRSIKGA"
     gene            11758..12537
                     /gene="ant6"
     CDS             11758..12537
                     /codon_start=1
                     /gene="ant6"
                     /note="dihydrocytosine hydrolase"
                     /product="ant6"
                     /protein_id="QEG98943.1"
                     /transl_table=11
                     /translation="MNAIRQRATDVPRYGDLTSAQVRQAMDGATLVWPVGGLEQHGPHL
                     PLSVDMDIPDALARQVVAEAGGLLLPGQPFSARSLPQSGGGLHFPGTVHIGGSTFIDYL
                     TDCLTSLARLGPARLVVINGHYENEGLLFEAIDDCAQATLFPDTEVLAFSWWSLVTEEW
                     LDEHIPHFPGWHAEHAGLTETSLMMYLRPDTVRAERPGHDAPPPAGVYRHPVDVDAISN
                     QGVLSSAVGASAELGESLFRHLVDGVVHLLGKPPRDS"
     gene            12587..13891
                     /gene="ant8"
     CDS             12587..13891
                     /codon_start=1
                     /gene="ant8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1152:nucleotide sugar dehydrogenase (Score: 349.5;
                     E-value: 3.7e-106)"
                     /gene_kind="biosynthetic-additional"
                     /note="nucleotidyl N-acetylglucosamine dehydrogenase"
                     /product="ant8"
                     /protein_id="QEG98956.1"
                     /transl_table=11
                     /translation="MPSTRPYEDYDVCVVGQGYVGVTLTAALLTTGRSVLGYETNPKVA
                     AELARGVLELAEPGVEEEIRGAAASGAFGVTTDVRGRKLPPVVIICVGTPIETGGTTPD
                     LSHLRAATEAIAGGIDETTLVIVRSTVPVGTSRSLVLPILSERVPEPLIAYCPERTIQG
                     QALAELLSLPQIVGGLSDEAGKRAAEFFGTLSDQVVPVSSLEAAELVKLVCNCHTDLIY
                     GFGNEVALITEKLGLDAREVIDSANLDYPRPNLHKPGFVGGSCLTKDPYLLAHSVAAYD
                     HVPQVITAARTLNESMPRRVGERVLAALSEQGVDPADARILISGFAYKGRPETDDLRGA
                     PYERLLPFLQGRVKEIVGHDFVVPAARIESLGVRPVDLTEGFTGAHAAILLNDHVRYGD
                     VDAADLVARMAEPALVYDTWRVLPSSTKAMRLGRA"
     CDS             13884..14876
                     /NRPS_PKS="Domain: NAD_binding_4 (70-191). E-value: 2e-12.
                     Score: 38.6. Matches aSDomain:
                     nrpspksdomains_QEG98944.1_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     233.8; E-value: 5e-71)"
                     /gene_kind="biosynthetic-additional"
                     /note="nucleotidyl-2-acetamido-2-deoxyglucopyranuronate
                     decarboxylase"
                     /product="ant9"
                     /protein_id="QEG98944.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.3e-09,
                     bitscore: 28.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.2e-13, bitscore:
                     40.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKILITGGAGFIGLHLARRLAASCDVTLLDDFSRGRSDAELAE
                     LLGSVELVEHDLTTPIPDGLLGDDYAEVYHLAAVVGVAESNDNPRRVLRTNLLTTVHLL
                     DWFSGLTGATLCFASSSEAYAGSVEAGVASVPTDEDVPLMVPDLTVPRSSYGFSKITGE
                     LLCRTYARTHGFALRMVRFHNVYGPRMGYDHVIPQFVERLLGGADPFEIYGADQTRAFC
                     YVDDAVDAIVALTALPTKEPLLVNVGNDQEEVLIRDLARHVFDALDRHPALDVHPAPPL
                     SPARRLPDIARLRELTGYSPAVPLCEGLRRTCEWYARHPRAAAAHGSGA"
     CDS_motif       13899..13955
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QEG98944.1_0001"
                     /evalue="6.20E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="QEG98944.1"
                     /protein_end="24"
                     /protein_start="5"
                     /score="18.9"
                     /tool="antismash"
                     /translation="LITGGAGFIGLHLARRLAA"
     aSDomain        14094..14456
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QEG98944.1_NAD_binding_4.1"
                     /evalue="2.00E-12"
                     /label="QEG98944.1_NAD_binding_4.1"
                     /locus_tag="QEG98944.1"
                     /protein_end="191"
                     /protein_start="70"
                     /score="38.6"
                     /tool="antismash"
                     /translation="AEVYHLAAVVGVAESNDNPRRVLRTNLLTTVHLLDWFSGLTGATL
                     CFASSSEAYAGSVEAGVASVPTDEDVPLMVPDLTVPRSSYGFSKITGELLCRTYARTHG
                     FALRMVRFHNVYGPRMG"
     gene            14873..15955
                     /gene="ant10"
     CDS             14873..15955
                     /codon_start=1
                     /gene="ant10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 154.3;
                     E-value: 8.7e-47)"
                     /gene_kind="biosynthetic-additional"
                     /note="enzyme involved in the biosynthesis of
                     4-acetamidopyrrole-2-carboxylate"
                     /product="ant10"
                     /protein_id="QEG98945.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.6e-29,
                     bitscore: 93.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGVRVRYVHRGYFPARAGAELMTQYLAASMSRLGWEAGIYSNPV
                     DEDTAAFMRGSGVSIQPLPATPDDTDRADLVHAIDAFHPQDIAAGLDLARAWSVPFAVT
                     PASAPDVWPDRETVLDGCRNADAVFALSEAERDMLRDAGVDGRRLHIIGQGPHLPGTPD
                     PEGFRRAHGIEGPMVLFLGRKTRSKGYVTLLEATEHIWRDHPDTSFVFLGPRWDDDCAE
                     HFARYAGPRVIELGMVDEDVKHSALAACELLCVPSTVDLFPLVYVEAWACGKPVVASTF
                     LGSAEIVAHGRDGLLVRPTPRTVADAVNRLLADPDERRAMGEHGHDKVRRELGWDAVAD
                     RVHTVYRTLTAARKQTEKAR"
     gene            15952..16716
                     /gene="ant11"
     CDS             15952..16716
                     /codon_start=1
                     /gene="ant11"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 173.3; E-value:
                     1.1e-52)"
                     /gene_kind="biosynthetic-additional"
                     /note="N-acetylglucosamine-1-phosphate
                     nucleotidyltransferase"
                     /product="ant11"
                     /protein_id="QEG98946.1"
                     /transl_table=11
                     /translation="MRAVVLAGGVGRRLRPHTLTIPKPLVPIDGTPILHIILAQLRGAG
                     FTHVSLSLGHRAHMIEASFTGNQWAGLELDFFLEEEPLGTAGPLALLPPFEDSTLVMNA
                     DLLTDLDFAELIARHKKSQAAATVALSRQYIDIAHGVVELDDDREVTDFREKPRLSFLV
                     NAGIYVLEPSLLRLLTPRVRDDMPALLDRARTEGERVEGHVIEGDWHDIGTPEQLNRAA
                     AAFRNDRARYLGRGAAAVLGAGTGAFQEVGSG"
     gene            16713..17864
                     /gene="ant12"
     CDS             16713..17864
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-217). E-value:
                     1.3e-09. Score: 29.4. Matches aSDomain:
                     nrpspksdomains_ant12_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="ant12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     365.7; E-value: 4.7e-111)"
                     /gene_kind="biosynthetic-additional"
                     /note="nucleotidyl
                     threo-2-acetamido-2-deoxy-pentopyran-4-ulose
                     aminotransferase"
                     /product="ant12"
                     /protein_id="QEG98947.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3e-111,
                     bitscore: 362.6, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAFDIALYRPHIGQAEIDAVTQVLRSGWLSNGPVTEDFEAKYAA
                     ALGVGSAVAVSSGTAALHLAFLSLDLGPGDEVVLPSLNFVSAAATVALSGATPVFADVK
                     GAHDLSIDPEDAARRVTPRTRAIVAMHYGGHPADLTALARLARTHGVALVEDCAHAPVT
                     DSPHGMLGTVGDIGCFSFFATKNLAMGEGGMVVARDPAVADRIRRLRSHALTVSAQQRH
                     HGGSSLYDVDTLGLNYRPTEIGCALGRVQLEALPAGQVRRQEAVQMYREQLAPLPGITV
                     PYADRPVEESAHHLFAVVLPAGTDRDALQDKLRAARIQSGVHYPPTHLFSAYQRRGRGG
                     PCRLPVTEDVMARQLSLPLHPGIGKDEVRQVVEAVSDAWPETP"
     aSDomain        16821..17363
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ant12_Aminotran_1_2.1"
                     /evalue="1.30E-09"
                     /label="ant12_Aminotran_1_2.1"
                     /locus_tag="ant12"
                     /protein_end="217"
                     /protein_start="36"
                     /score="29.4"
                     /tool="antismash"
                     /translation="EDFEAKYAAALGVGSAVAVSSGTAALHLAFLSLDLGPGDEVVLPS
                     LNFVSAAATVALSGATPVFADVKGAHDLSIDPEDAARRVTPRTRAIVAMHYGGHPADLT
                     ALARLARTHGVALVEDCAHAPVTDSPHGMLGTVGDIGCFSFFATKNLAMGEGGMVVARD
                     PAVADRIRRLRSHALTVS"
     gene            17846..19747
                     /gene="ant13"
     CDS             17846..19747
                     /codon_start=1
                     /gene="ant13"
                     /note="putative glycoside hydrolase; enzyme putatively
                     involved in the biosynthesis of
                     4-acetamidopyrrole-2-carboxylate"
                     /product="ant13"
                     /protein_id="QEG98948.1"
                     /transl_table=11
                     /translation="MAGDTVSGGRVTFADGALYRDGHPYVSVGVNYHPSPTGCEYWREW
                     DGDRIDDDFRRMAAEGLNTVRFFVFWADFEPKEGVYDSTATDRLRELVRTARRHGLLCL
                     PSLLTIWMNGQRFDLPWRDGRDLWRDPDLRERQRAFVHHIAAELRDEPNVLAYDLGDEV
                     IHVDSRSSASLGPDEVRAWWGMLASSIRDADPDALVLQANEPSAVLGGHAFRPEHADSL
                     DMVGLHGFPVWTPFHVESVAARKATAFVPYLVRRGSAHRPVYVDELGSYGCDGTTAARY
                     LRAASHSAFAAGAVGTAVWCWQDFTTERKPYALRPNERRVGLLDADGGEKPVLAEYREF
                     IRRVTGELAGFRPLPAPVGVFVPEAEEQEEAGYLTPSGSDAPAAFYAHLLLQQAHLPYE
                     FTGRDPELERHALVICPSARTLSLPDRRRLARYVSAGGVLLYSTGSLLDAAGDEDLFGI
                     RVRDFTRADDTHAEFTWAGTRFPLRWDTGPIPVIDTAGAETLAAFADGSPALTRHRLGE
                     GSVYYLNAPLEAQLNAPYRLDETDWHRLYEAVAEQAGVRAPLTAEDPSVETTVLGRGDE
                     RCGVVINHAPEPVDTVLRRHTADGTTESEKPLHLEPKDVRLLFWHGDEPQRPEGRQP"
     gene            19744..20646
                     /gene="ant14"
     CDS             19744..20646
                     /codon_start=1
                     /gene="ant14"
                     /note="4-acetamidopyrrole-2-carboxylate deacetylase"
                     /product="ant14"
                     /protein_id="QEG98949.1"
                     /transl_table=11
                     /translation="MIIDAHVHAGEYYRHYTARFAEQMTATTDLAPEDLTAPEAKLLAE
                     MDAAGVDRVFLLAFDVRRVEGFSVPNEFVADLCARHPDRLTGFASVDAGTPGAAERLRE
                     AVTDLGLRGLKTAPCYLRMSPADRRWYDVYETAAELDIPVLIHTGYTPSRNAAPRFFSP
                     LLVEQVAKDFPGLKVILAHLGTPWTGPCVELLARHPDLYADLSIFGSYQPPAVVARALA
                     HARDRGVLDRLLWGTDFPFASMTGSVARTAELARDPGPWPDGSDPLSPREYEDLMGGTA
                     ARLLAPTAPHAAPVPPPHR"
     gene            20658..21464
                     /gene="ant15"
     CDS             20658..21464
                     /codon_start=1
                     /gene="ant15"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 99.4; E-value:
                     3.9e-30)"
                     /gene_kind="biosynthetic-additional"
                     /note="Methyltransferase'"
                     /product="ant15"
                     /protein_id="QEG98950.1"
                     /transl_table=11
                     /translation="MTFVHGYEFDAMSRRPLYGDVTQRLVDICEAPEGGVVADVGCGSG
                     LATELLLERSAHVGSIIGIDPSEHELTIARARLTDPKVRFVQGRAQDVESLTGPVDVAV
                     LSNVMHQIPADERGAVLAGCHRLLAPGGRCALNTLFYEGAVLPGTRPFYTHWLRATRAV
                     LRDRGTDLVLVRERPVAMQTLTPRQHEDLFADAGFSQTKSEEAEYTWTLADWEALCAYS
                     VFIEGATGISDLALGSDALIRGLRTTFEELELSGVPRRWLFTWGVK"
     gene            21461..22795
                     /gene="ant16"
     CDS             21461..22795
                     /NRPS_PKS="Domain: Condensation_LCL (7-316). E-value:
                     5.2e-79. Score: 257.2. Matches aSDomain:
                     nrpspksdomains_ant16_Condensation_LCL.1"
                     /codon_start=1
                     /gene="ant16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     390.5; E-value: 2e-118)"
                     /gene_kind="biosynthetic-additional"
                     /note="Nonribosomal peptide synthetase condensation domain"
                     /product="ant16"
                     /protein_id="QEG98951.1"
                     /sec_met_domain="Condensation (E-value: 2.3e-63, bitscore:
                     204.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPRGDAPLSYAQQGMWFLERRAGHARHTVAVTFRLVGDLDAA
                     ALRAAIEDVVDRHEALRTCFPVVAGLPVQRVVPRVEVPLPLTDLTALPEAEREAAAARF
                     LAEDLRRPFDLVRGPVVRAALLGLGPREHILRVSSHHLVSDAWSWWVVILRELEQLYTA
                     HLHGRPSPLPPVPAQYGDFARRQHEWLDGPAGAKQLAYWKEVLATASPLPPLTLASPPA
                     SPSGPPSAPPEAEEPSRTQWTAVPQPLYDRLQATARREHVSLFMLLLAASKRMLRRHVD
                     TDDILVGTRGGFRSSAEFEKAVGLFVNLLPVRTHVAADADFRDLLHRVRRNLIGAYTHR
                     DMPFERLVQVLGLWRPGFRPVIGACVTFQTAPEVPPALEGLDTTPINHDPFSAHPLDLG
                     FFEEAGALRVLLAYDPAQYDDKAAARLLDDLHEELDAGCRELEDA"
     aSDomain        21482..22408
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ant16_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="5.20E-79"
                     /label="ant16_Condensation_LCL.1"
                     /locus_tag="ant16"
                     /protein_end="316"
                     /protein_start="7"
                     /score="257.2"
                     /tool="antismash"
                     /translation="DAPLSYAQQGMWFLERRAGHARHTVAVTFRLVGDLDAAALRAAIE
                     DVVDRHEALRTCFPVVAGLPVQRVVPRVEVPLPLTDLTALPEAEREAAAARFLAEDLRR
                     PFDLVRGPVVRAALLGLGPREHILRVSSHHLVSDAWSWWVVILRELEQLYTAHLHGRPS
                     PLPPVPAQYGDFARRQHEWLDGPAGAKQLAYWKEVLATASPLPPLTLASPPASPSGPPS
                     APPEAEEPSRTQWTAVPQPLYDRLQATARREHVSLFMLLLAASKRMLRRHVDTDDILVG
                     TRGGFRSSAEFEKAVGLFVNLLPVRTHV"
     CDS_motif       21494..21526
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ant16_0001"
                     /evalue="3.70E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ant16"
                     /protein_end="22"
                     /protein_start="11"
                     /score="9.9"
                     /tool="antismash"
                     /translation="SYAQQGMWFLE"
     CDS_motif       21554..21658
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ant16_0002"
                     /evalue="1.40E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="ant16"
                     /protein_end="66"
                     /protein_start="31"
                     /score="49.5"
                     /tool="antismash"
                     /translation="VAVTFRLVGDLDAAALRAAIEDVVDRHEALRTCFP"
     CDS_motif       21878..21943
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ant16_0003"
                     /evalue="3.40E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="ant16"
                     /protein_end="161"
                     /protein_start="139"
                     /score="19.7"
                     /tool="antismash"
                     /translation="HHLVSDAWSWWVVILRELEQLY"
     CDS_motif       21992..22030
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ant16_0004"
                     /evalue="2.10E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="ant16"
                     /protein_end="190"
                     /protein_start="177"
                     /score="10.9"
                     /tool="antismash"
                     /translation="QYGDFARRQHEWL"
     CDS_motif       22310..22399
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ant16_0005"
                     /evalue="4.80E-07"
                     /label="C5_LCL_267-296"
                     /locus_tag="ant16"
                     /protein_end="313"
                     /protein_start="283"
                     /score="22.3"
                     /tool="antismash"
                     /translation="DILVGTRGGFRSSAEFEKAVGLFVNLLPVR"
     CDS_motif       22448..22519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ant16_0006"
                     /evalue="2.50E-08"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ant16"
                     /protein_end="353"
                     /protein_start="329"
                     /score="26.2"
                     /tool="antismash"
                     /translation="RRNLIGAYTHRDMPFERLVQVLGL"
     gene            22792..23838
                     /gene="ant17"
     CDS             22792..23838
                     /NRPS_PKS="Domain: PKS_ER (123-272). E-value: 7.4e-08.
                     Score: 23.7. Matches aSDomain:
                     nrpspksdomains_ant17_PKS_ER.1"
                     /codon_start=1
                     /gene="ant17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 320.8; E-value:
                     1.4e-97)"
                     /gene_kind="biosynthetic-additional"
                     /note="4-acetamidopyrrole-2-methanol dehydrogenase"
                     /product="ant17"
                     /protein_id="QEG98952.1"
                     /sec_met_domain="ADH_N (E-value: 1.4e-29, bitscore: 92.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.4e-23, bitscore:
                     71.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALRWHGTRRAEVADDVAMPRVEEPRDAVVRVVRSAICGTDLHP
                     YRGEIDGFPAGTVTGHEFTGVVEETGPEVRGLRAGDRVVASDIIACGHCRSCRHGWHYQ
                     CDRVGLFGYATVVGTRAYAGGHAEFVRVPFADTVLFPIPDDVGDERALFVGDVLATGYA
                     CAVGAGVRPGDTVAVVGCGPVGLLALEVAWLLGAARVLAVDPLESRRKLAAERGAYPVP
                     AAPDVARQVADLTEGRGADAVLEAVGTDASLLTALNVVRPRGTVCAVGAHASDAMPMPT
                     RLAFAKEVTLRFAVGDPVGDFEPLMNLVRGGRVDPTYLISHRMPLSEAAEGFRLFDAGE
                     ASKVVLIP"
     aSDomain        23161..23607
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ant17_PKS_ER.1"
                     /evalue="7.40E-08"
                     /label="ant17_PKS_ER.1"
                     /locus_tag="ant17"
                     /protein_end="272"
                     /protein_start="123"
                     /score="23.7"
                     /tool="antismash"
                     /translation="GGHAEFVRVPFADTVLFPIPDDVGDERALFVGDVLATGYACAVGA
                     GVRPGDTVAVVGCGPVGLLALEVAWLLGAARVLAVDPLESRRKLAAERGAYPVPAAPDV
                     ARQVADLTEGRGADAVLEAVGTDASLLTALNVVRPRGTVCAVGAH"
     gene            23928..24269
                     /gene="ant19"
     CDS             23928..24269
                     /NRPS_PKS="Domain: PCP (22-69). E-value: 6.4e-12. Score:
                     37.4. Matches aSDomain: nrpspksdomains_ant19_PCP.1"
                     /codon_start=1
                     /gene="ant19"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="nonribosomal peptide synthetase peptidyl carrier
                     protein"
                     /product="ant19"
                     /protein_id="QEG98953.1"
                     /sec_met_domain="PP-binding (E-value: 7.3e-11, bitscore:
                     33.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNLAAQSPSTSGDAEAAAEVVRRIWAQVLEVSPDSVDVHHSDF
                     FEMGGYSLLALQAIGRILAEYGVDEVEAVEWEGELLNRLFENATPMTQAEFLAEKGCGT
                     PSAANSTHV"
     aSDomain        23994..24134
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ant19_PCP.1"
                     /evalue="6.40E-12"
                     /label="ant19_PCP.1"
                     /locus_tag="ant19"
                     /protein_end="69"
                     /protein_start="22"
                     /score="37.4"
                     /tool="antismash"
                     /translation="VRRIWAQVLEVSPDSVDVHHSDFFEMGGYSLLALQAIGRILAEYG
                     VD"
     gene            complement(24354..25697)
                     /gene="ant23"
     CDS             complement(24354..25697)
                     /codon_start=1
                     /gene="ant23"
                     /note="amidoligase"
                     /product="ant23"
                     /protein_id="QEG98954.1"
                     /transl_table=11
                     /translation="MPDTIDLVVPNVVEFNLKRELLDFDPGVENDLVEHGTGYTDQCVF
                     WSAGDRVLVLPAGYSQEWLTHVHAGLGSSVPDVISPLPRTGRLIRDLLDDDRALAALAA
                     ATDGVREVRLLSFGASPDLYSLASVLRSQGREVRLDVAGPEHYWSYEYLESKLCCVDLA
                     SHIPGFRVPRGISVTSWEQLKGAVTTIVGNGGRAVVKSMYGVGGYGSAVARGDADGTVR
                     RFWQTLRREPFFGTFPLTVQDYIAHGTDCPAVDVLVDEGAVPRMEYSMLGVDGLRYRSL
                     ALGPGVLDPDLEERLAALGTAVHTFAQSLGYRGWMTVDCLRGLDDALYVTEINARRSGA
                     MHAVALAERWADEVPVAYVNDALPLRLSGPVSYEEHIRPVFDELWARGVRAYPSTVRAL
                     TGHRPSLGIVVCARSAADGERIATEAHRAVNAAVTAAGAGQKRAAAVG"
     gene            complement(25736..26113)
                     /gene="ant24"
     CDS             complement(25736..26113)
                     /codon_start=1
                     /gene="ant24"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /note="5-amino-3,4-dihydro-2H-pyrrole-2-carboxylate
                     synthase"
                     /product="ant24"
                     /protein_id="QEG98955.1"
                     /sec_met_domain="ectoine_synt (E-value: 5.6e-26, bitscore:
                     82.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVRSVEDVVGSEYDVDWGNGTSRRLLVQADELGFSLTETYVQPG
                     SESYLRYDNHQEVCYCVSGAGSVETADGLFDIKPGMLYAPGMGEPHILRSEHGMTLMCV
                     FSPALQGPEKHLLTPGVHSSY"
ORIGIN
        1 ctaggaccgc ctgacggccg ccgcggtccg caccgcggcg cgtctgatct tgcccatcga
       61 gctcttcggc agcgaggcga cgaagtcgac ctcggcgggc acctgatggg ggaggagccg
      121 ggcgcggcag tgggacgtca gctccgtcgc gggcagcgga ggccgcgcca ccacggacgc
      181 ccgtacgcgc tcgccgccgt cgtcggtcgt ctcgccccag accacggcct ccacgaccga
      241 ggggtgggcc agcagggctt gctccacttc gagggggttc accttcttgc cgcccacgtt
      301 gatgaaggag tccttgcgcc cgaccaggtg cagatggccc tcggggccga cgcgggccac
      361 gtcgccggtc cggtaccagc cgtcggcgaa cgcctcccgc gtggcgtcgg cgtgcccgag
      421 atagtgcgtg aacatcgcgg gtgtgcgcac cagcagcgcc ccttcctcgc cgcgtgccac
      481 ctcgtcgccc cgctcgtcga cgacacggat ccgcacgccg ggcatggggc ggcccacacc
      541 gaggtccgcg gccgagccgt cctccgggcg ccgcgcggcg atgaccccgg cctccgtgca
      601 gccgtacacc tgctggatgt ccagaccgag ccgctccttg gcccgccgcg ccacggcggg
      661 cggcagggcg gcccccgagg acaggcacag gcggagggca cggggcacgg acgggctcgc
      721 gccggccgcg cgcgtcgtca ggtcgtaggc catgggggcg gcgaccagga ccgtgcaggc
      781 gtgctcctcc agggcgcgca ggagccgtgc gggggtgaag cggccgagga ggacgagttc
      841 cgccccggcg cgcagcgcgg tgaccagtcc ggccaccagg ccgaaggagt gcagcagcgg
      901 gacggcggcc aggatgcggt cgtcctcggt gatcccgtag gaacgggcgt agatgtcacc
      961 gccgttgacg aggttgcgct gcgtgtggac ggccaccttg ggctctccgg tcgagccgga
     1021 cgtgtactgg tggaggaagg gggcgtcggg catggcggcc gcgtcgcctt ccggcacccg
     1081 ggagggggtg tcgccgcccg ggtcctcgat ggggatgaac gcgcagtcga gcgggtccgg
     1141 accctccgcg ccctccagcg cggcgagcct cgcggtgtgg cccatgacgg acagcggccc
     1201 caacgcctcg cgcacggaac cgagttgtgt acgtgtggtg ccgggttcca gagggaccag
     1261 gcgcaccccg agccgggccg cggcgagaag cgcgacgacg gagtccgggg tgttctccag
     1321 gagcagcccc gccgcgccgc gcccggtgac gccgagcgcc tcgaagcgcc gcgcggtggc
     1381 ccgcaccctc tcgtgcagct cgccgtaggt caggacggcg tcctcgccgc gcacggcgac
     1441 ggcgcggggg cgggcacggg cggcactgtc gagcagttcc cggagggttg tcgggccggg
     1501 ccggccgggt ccgtcggcct ggtgttcaga cgcggtggcc atcgaccacg ctctcctctc
     1561 cgtcctggtc cgcatgtccg ttcgccgacg ccaccgcacc cgcgaaaggt gtgagtgcga
     1621 cgggccgggg ctccacgggc tcggcggggt cctcatcggg gcgctggtgg cggaagtagc
     1681 ggtcgtagag gcgccggtac gccccgccac gggccagcag cgtggcgtga tcgccctcct
     1741 cgatgatgcg gccctcgtcg acgacgacga tcgtgtccgc cttgcggacc gtgggcaggc
     1801 ggtgcgcgac gacgatcgtc gtgcggtccg ccgcgagtgc ctcaaggccc tcctggatct
     1861 gggcctccgt cagcgggtcg atgctggcgg tggcttcgtc gaggatcagt acgggggcgt
     1921 cctggaggaa gacgcgggcg agcgcgacga tctggcgctg gccggtcgac agattccggc
     1981 cgccctcgtc ggtgggtgtg tccaggccct gtgcgagctg ctccagccag tcaccgcccg
     2041 ccaccgcgcg cgccgcggcc tcgatctcgt cgcgtccggc gcccggccgg ccgcgggcga
     2101 tgttgtcggc gaccgtcccg gagaagagga acggcgtctg tgtcaccacg ccgaggcagc
     2161 gccggtactg gtccaggtcc aggctgcgca cgtcgaggcc gtcgacctcg atgctcccct
     2221 tctggaattc gtacgcgcgc atgatcagcc ggaccacgct cgactttccg gcgccggtgt
     2281 ggccgaccag tgccacggtg cggcccgcgg ggatgtcgag gctcacgccg ttgagcacgg
     2341 ggtgttcgtc gtcgtagccg aagtggacgt cgcgcagggt gatctcgccg cgcaggcgcg
     2401 gtaccggcac ccggtcgagc tggcgcaccg tcgactcgcg gtcgacgagg gcgaagaccc
     2461 gctcgcccgc ggccagaccc tgctggagct gactccagaa ggacgcgatg ctggtgagcg
     2521 gcgaccagaa cagggccagg gcctccagga acagcaccca ctcgcccgcc gacaccgagc
     2581 ccgagtcgac gccgtgtccg cccaccagga ccaccgcgac cgtgccgagt cccgtgaggg
     2641 agatcagcag cgggaagatg ccgctgaaca ggcggttcag ccggacgctg gccttgaacc
     2701 accggtggtt gacctcgtcg aggccggtct gcgcggactg ctggtggctg tggttgcgcg
     2761 ccacggcgat gccccgcagc gtctcctgca catatccgtt gacctcggcc agggcctcct
     2821 gctggcgcag cgaggcgctg cgggcagcgc gccggaaggc gaggctgacg gcgacgatga
     2881 ccgctgcgac gaaggccgtc acgagggcca gcggcacgtt gatgacgaac agggcggtca
     2941 gcaggatcac gatcatcagt acctggccga gcaggctcag catcagggtg atcagcgtcg
     3001 cgaaggcctg ggtgtcgttg gtgacgcggc tgacgactac accggtcggg tgcgcgtcgt
     3061 ggaacgccat gtcctggcgc atggccgccg cgaacgcccg ctcgcgcagc ttgagcacga
     3121 cgtcaccggc catggtcccg gccgcgcgct cctgaaggag gttcagcagc caggcggcga
     3181 tgcccgcgac gagcatggca gcgaccagcc acgcgagacg gccgtcgccg tcgtccttca
     3241 gggccgagtc gacggtccgc gccaggagca gcggcacggc gctgcccgcc gtggcggcga
     3301 tgatcacggc gagggtcacg aagaccacgg cccggccctt gccgcggaag tacggggcga
     3361 tacggcgggc cagctcgcgg tcgccgtaac ggcggtcgta gtcgtccggg tcgatgccct
     3421 ccagcagatg cgccatcagt ggctctcctc cttggcgccc gcggagtccg ggccaccggg
     3481 tgccggcgtg ctcagatagg gcgcgaagat cctgcggtac agggaacagt cccgcaggag
     3541 ctgttcgtgg ctgccctggt cgacgatccg gccggcgtcc aggacgagga tgtggtcggc
     3601 cgcccggatg cgggacagcc tgggggtgac gaggaacgtg gtccgtccgt ccgaggcctg
     3661 ccgcatggcg cgctgcacct cgtactcggt ggcgctgtcg acggcactgg tcgcgtcgtc
     3721 cacggcgagg atgcgcgggt cggcgatcaa cgcgcgggcg atggcgaggc gttggcgctg
     3781 gcctccggag agggtgacgc cgcgttcgcc gatgacggtg tcgtagccgt tctcggccgc
     3841 cgtgatgaag tcgtgtgcct gcgcgatgcg ggccgcgtcc tccatgcggg agcggtcggt
     3901 cccgttgtcc gaaccgaggc tcaggttctc cgcgatggag cgggagaaga gcatcacgtc
     3961 ctgctcgatg acggaggtgc gcgagcggag cgccccgatg tcccagtccg tggtggggac
     4021 gccgtcgacg aggacgcgtc cttcgtccgg gatgtaggtg cggttcagca ggtgcaggag
     4081 ggtggacttg ccgcttcccg tggcgccgac gatggccacg gtggtgccgg gggcgacccg
     4141 gaaggacacg tcgcgcagca ccggcttgcc gggttcgtag ccgaacgtga cgttctccat
     4201 ggcgacttcg ccgacgacgg gtccggtgtg gcggccgccc cgctcgtcct cgccctcggg
     4261 gtcgtcgacg acctccttga tgcgctgcgc tcccgccatg ccgaggtaga tgagcccgag
     4321 gctgaaggac gccagctggg tgggggcgcg cagggtgccc atcagtccca ggacggcgac
     4381 gagttcgccg atgctcaggg agtcgtcgcg cagcaggatg acggagtgca ccagggcgcc
     4441 gacggtggcg agggtcagca gcagcgggga cagggcgagt gcctgggtgc ggatctggcg
     4501 tacggaggcg tcccggtacg cgcgggcaag atcggtgaag cgggcgcgtt cctggtcggc
     4561 accgccggtc gaccccacga cctcgatgcc ggcgatgctc tccgacgcct gggcagtcat
     4621 gtcgccgaag cgctcgcgtg ccgtgtcgga gacgggctcc agacgacgcc cgtgttcggc
     4681 gagcgccacc gcgaacagca ggacgaagac gacgggggag accagcagcc gcgggtccac
     4741 cagggcgatg aacacgatcg gcatcaggat gttcagggcg aggtcgacgg ccaggtcgaa
     4801 gcctggtgac accatcaggt tcagcgactc cgcgtcgccg gtggcccgtg cggacaggtc
     4861 gccgacgcgc cgccggttga agtagccctg gctcttgcgc agcaggctgg cgaagacctg
     4921 ggcgcgcgcg ttgcgctcga gcccactggc gaaggactcc aggctgtacg tggacatgat
     4981 gccgcccagc gcgcggacga ccacgagcgc gaacaggccg gcggcgatgg cgtggaacgt
     5041 gccgaagtcg ggcgatccgt cgtcctggtc gaggacggcg tcgaaggcaa ggccggtgac
     5101 cagcgggatc gccgcggtca gcgactgcca ggcgaggctg cccagcagga acagggcgat
     5161 gtacggcctg aagggccgca tctgtgcgag cagccagcgg gggacgctgc gccggtcggc
     5221 gtcgtcgtcg gtgtcgtcgg ctgccgtggc gcccgccatg gtctcggcgg tcatcggcgc
     5281 tccttgtccg tggtcgaggg ccgcagcgtc tccgggtccg gagagatccg gaggtccggg
     5341 cgtccggagg tccggaggtc ggaaaagaca gcgacgcatg gttttcggcc atcacttagc
     5401 gaatttgtgg gcgagcggca cgcaggcctt tccggccgcc aatgtgaatt cggtccggcc
     5461 ggaatgggag tgtcgccgta ggtggccgcg cgaacggatc acccggcgcg cctgtggggt
     5521 ggcggtgggc gaggcgggcg tgccgtggca tggaagctac tggttttcac cccgaaagga
     5581 aagtccgcat ccgggctgcg cgaatacccg cgagttgaaa attaaatcaa ccgtacgcgt
     5641 ggtgtgccga ggtctttttc gggccgctcg gcctgaacgg gtcgcgtcaa gtggaatggt
     5701 tgaagtcgct tgaaacgtct gggtactgtg atgagtgtcc agtgctgaaa agcgctcgca
     5761 actgcgtacc tattgcaggt ctgtgcagtg gtgagccggc cgcggcctgc cggtggacgg
     5821 cgcggggcgg cgtcatctcc ccacgtcgga tacggcggga accgtggcga cagtgaggag
     5881 gaatgcgagt gagtcaggcg ctgtgccacc ccccgttccc aggagagcag ctcgtggtga
     5941 ccactctcgt gcgcaacgga ttcctgcagc tcgggctgcg ggccgcgctg tcgacggcgc
     6001 ccctggtcag ggacgtcaga cactgcggcg actggggcga ggtggaggaa accttacgca
     6061 acaaccaagt ggacgtgctg ttcctgcacg agaaggacta cagcccggat cgaggcgtgc
     6121 tcgtggacgc ccgacggcac cgcccgaaga ttctccttct gctcaccacc accgaggtcc
     6181 ccgaagaaat actcgcgggt ccctcggtac ccgacggatt cctggtcgag aacgagttga
     6241 ccgccaccgc ggtcgaggac gcgctccaag ggatcgtggc cggcgaggtg cccatgccca
     6301 cctcggtcac ccgggcgctt ctgcggcgcg tccgggagcc ggaacagcag cgcaggcggc
     6361 gcgtcggcaa cctcaccggc cgtgagaacg aagtgctgcc gctgctcgcc gaagggctga
     6421 gcaacaaaca gatagcccgg cgcctcggca tctccagcca cggcgtcaaa cgcatcgtcg
     6481 ccagcctgct cctcaagctc ggcgcaccca accgtacggc cgcggtggtc accgccatac
     6541 agaacggact catcacctga gggcacgtca tatccctgtc cgcccggtgc cccacgctgc
     6601 cggagctgtc ggcaccgcgg ggttcgtccc gccgggcgga cagggacgct tccttttcgg
     6661 aagtctctgc gtcgagtgcg tccgtaagtc tctacgtcgc gtgtgacggc ctttccgaaa
     6721 atccggaaat ccgcatgccg tgcggcgcga cgcgtcggtt aactcgcatg cccccgatac
     6781 tcgtggtgcc cgaatggtgt gggaagcccc caccgggcgc ccgttcggtg cgccgtatcg
     6841 ggcagcccga gcgggtggac ggtgaccgaa cggtcagccc cgaaagcgcg ggtgccgctc
     6901 gcgcgaaccc ggcgttacgg tgaatcggcg cgtccccacc cacctcatcg tgctggaaag
     6961 gaccgagccg tggccgaatt cgtccggcac cgcatcccct tcgctggacg acggtcggtc
     7021 accgcgccgg cgacctgcgc ccagcggcac ctctggaatc tgatgcagcg gcagctgccc
     7081 gacgcctcct tctacgacgt gtgctactgg gtggcgctgc ccggccacgg caccgcacag
     7141 gacctgctcg acgtctgcgg cgaactggtc gtacgccacg agtcgctgcg cacggccttc
     7201 caccgggacg ccgatggctc cctcgtccaa cacgtcgtgg atgccgccga gttcgaggcc
     7261 gaggtgtgga cgctcgcccc acacgaagac cccgacggtg tgcgccgggc ctgggagcga
     7321 aggatgcggc acaccccctt cgaccccgca cgggccccgc tcatccggtt catggtgacc
     7381 gtcgtcgacg gcgttcccgt gctcgccgcg ttctgtgtgt cccacctctc ggtggacctc
     7441 acctcggtgc ggctcctcgc cgacgagctg acccggctgc tcgacgcgcg ggcggccggc
     7501 cgccccctgc cacccgccgc accggcacgg cagcccgtcg agcaggcaca gctggagcag
     7561 tccccgcgcg gccgtgccct gcaggcgcgg tcacgcacct actggcaacg gcagctcgac
     7621 cgcgcgcccg cgaccctgtt cccggaccgc ggcggccccg cggccccggt ccggtacagc
     7681 gccggcatga gctcccgtgc cgtggcgctc gcggtgccgg tcctggcccg gcgctggcgg
     7741 gtgagcacgt ccgtcgtgct gctgaccgtc gtcgcccggc tcctcggacg ccgggccgga
     7801 tcgccgtcgt gcaccctgcg cctgctcacc gccaaccggt cggaccccga tgtgcgcggc
     7861 accgtcgcca acctccacac ggaggtgccg gtgaccatcg ccctggacgg cgaccgcgcc
     7921 gaggacgtcg cacgccgcgc cctcgccgcg tgcaccgccg cctacgcgaa cggcctctac
     7981 gaccccgacg acatcgcgcg tctgatcgcc gacgcccgcg gacccggcgt accagtggac
     8041 ctctcgtact gcttcaacga catccgggag gaacagcccc tgcccgacac ggccgacggc
     8101 gacggtgccg tgtccggcga gagcccgcgg gccgccatgg ccgacaccgt cgtcgctccg
     8161 gacgagttcg aggagggcga gaccttcttc gtcgtggtcg acgacgaggt tcccggctgg
     8221 atccgcgtgg tcctcaacgc cgaccaccgg gcgctcaccc cgtccgaggt ccacgcgttc
     8281 ctccacgaca tcgagcgcct gctcgtcgag tacgtcgagg acgccggggg agagcacggt
     8341 cccgccgccg cggtgggcgg cgcggggagg ggcgcggcca cagagtcgta agggccaggg
     8401 gcccgctccg acgcgcgccg accgtccggc ttccgcctgc cgacggccgg cgccgcggca
     8461 tgcccggacg cggaccggcg acccccgtgc gcaggatgat cccagcaggt cagcgcgtcg
     8521 gccatgtgca tcggaccggg ctttcggagt agccggatga ccctagccca aagtgggggt
     8581 gttcgatcac cggggacccg gcaagactgt tccacgggcc gcccggttcg agcacggcag
     8641 gtcacgggag acgcggagtc ccgacagcgg gacacacccc ctcccaccgc tccgccgctc
     8701 gcaccgcgcc ctccctcttc ctccctcccc gcggccccgc gcctctcagc agtcgacagt
     8761 cgacaaccgc ccctacgcga ccccctcgtg acgggaaccc atgtcctcat ctgttgatca
     8821 actcgcctcc ccccgcgccg ggctcccccc gggcgccccc ggctccgtgc gctacgggcc
     8881 gaacccggtg gagaacccgg cactcggcaa ggtgttcgcc gaaaccccgg gatgcacgcc
     8941 cgaacggctc gacgacgtgc tggacgacgc ggcccgcgcc ttccccggct gggcggccac
     9001 ccccctggcg gaacgccgcg agtggctcca ctcctgtcac cgcgccctgc tcggtgccgt
     9061 ggacccgatg gccgaactgc tcaccaggga acagggcaag cccctgaaac acgccagggc
     9121 cgaagtccgc ctggccgccg actggttcgc ccgcaccgcg gagctggggc tcacgcagga
     9181 gcggctcgtc gacgagaccg acgcccggat cgacctggag cgcgtgcccc acggcgtggt
     9241 cgcggcgatc gccccctcga actaccccgt cctgctcgcc gtctgcaaga tcgcccccgc
     9301 cctcctcgcc ggcaacaccg tggtgctcaa gccgtccccg gacaccccgc tgtccagcct
     9361 gatgatgggc cggatcctcg gcgacgtcct gcccgccggc accttcgcgg tcgtggacgg
     9421 cgacgtcgag ctcggcgccc gcctgaccgt ccacccggcg gtccggctcg tgtccttcac
     9481 cggatcggtc ggcgcgggcc gcgccatcgc ccggcaggcc gcggccgacc tgaaacgggt
     9541 cgtgctcgaa ctcggcggca acgacccggc cgtcgtcctg cccggcaccg acgtcctgtc
     9601 cgtcgcaccg gacctgttcg ccgcggccat gaccaacagc ggccagttct gcgccgcggt
     9661 caagcgcgtc tacgcgcccc gagcgacgta ccgcaggctc gccgaagccc tggcggagaa
     9721 ggcgcgcacc gccatcgtgg gtgacgggct cgatccggcc accgaatacg gcccgctcgt
     9781 cagccgcgcc caactgcacc acgtcgcggg cctggtggac gacgccgtgg cggcgggagc
     9841 cgacgtcctg gccggcggcg ggccactcga cggaccgggc cacttctatc cccccaccgt
     9901 cgtcaccgac ctgccgcccg gcagccgcct cgaagaggag gaacagttcg gcccggtgat
     9961 ccccgtcatc ccgtacgacg acgtggacca ggtcttcgca caggtcaacg cctcgacgta
    10021 cgggctcggc tgctccctgt ggggcgacga ggaacgggcg cgggaactgg ccgggcgacc
    10081 tcagtgcgga accgtgtgga tcaacacgca cggcgccctg cggcacgacg tgccgttcgg
    10141 cggccaccgg cactccggga tcggcgtcga gtacggcgcc tggggtctga acgagtacac
    10201 acagctcaag gtgcaccaca gcgcgcttcg ccttcgccct cgccaagcag atcgggagac
    10261 gtcatgagtg acagcacggt ggtccgcgtc gacggtacgg acggcatcga cctgacggga
    10321 gtcaaggtgt tcgtcggcgg ccccatccag cacgcgatcc gtgacgacgg cttccaccag
    10381 ccgttgcagc acgcgatcgg cgacatcatc gaagccgtca ccgccgcgca cggcaccgtc
    10441 ttctccgccc acgtggccga gaagttcggc gtcgacacgc ccctgttctc gccggaccag
    10501 gtcagcgtcc gcgacatcgg ctggatgcgc cgctgcgacg tgttcgtacc ggtgctgccc
    10561 gtggacgccg ccggtgaact gatgcgcacc gacggcaccc acgtcgaact cggctgggcc
    10621 tccgccctgg acaagcccat cgtcgtcgtc accccgatgc cgatggcggc caacgccagc
    10681 cacctgctgc gcgggcttcc gtccgtcgcc gacgtcaccg tcttcgacct ggaggaggcg
    10741 cgggccaacc ccgtcgaact gctccggctg ctcgaaaagc tgggccagga agcagtgatg
    10801 gcgccgtgac ggcagccgag gacggagcga atggagccga ggcgcccggg gccgccgcca
    10861 ccgcggcccc ggtggagatc ctcggcctgc gcctgaagtc cccggtcgtc gtgggctccg
    10921 gcctgctgac cgaccaggaa cgcaacatcc ggcgactgct cgacggcggc gcgggggccg
    10981 tggtcaccaa gaccatccac cccaaccccg gaccgcccgg caacgaacgc ctgctccggc
    11041 tgcccaccgg catgctcaac agcaccacct actcccgccg ttcggtggac gactggtgcg
    11101 cgatgctgcg ccggttcgcc gacgacgacc tgccggtgat cacatccgtg cacgcggact
    11161 cgccggccga actcgccgac ctggccgagc gcgtgaccga ggcgggcagc accgcactcg
    11221 aactcggcat ctcgtgcctg aacgaggagg acggcggcct ggaggacact cccgagcgcg
    11281 tcgccgcgta cacggaggcg gtgcgcagcc gcaccccggt gccgatcagc gtcaagctgg
    11341 ccatcgggga gcgggtgcgg gaacgcgtcg acgccgccac ggcctccggc gcggacgcac
    11401 tcaccctcag cgacaccatc tccggcctcg ccgtcgacgc ggacaccggg gaggtgcgcc
    11461 tgggcggcgc gttcggctac tccgggcccg gcatcaaacc actggtgctc gccgagatct
    11521 acggcctgcg ccgcgacggc ctgaccgtgc ccgtcatggc gagcggcggc gtcaacgacg
    11581 ccgtggacgt cgcggagtac ctcagcgtcg gcgccgacgc cgtgcaggtc tacacggtgc
    11641 tgcacaagaa catgcacgcc acgctccgcg ccatccgcca gggcttcgac gactggctcg
    11701 cctcgcacgg gggcacggtc gcggacctgg tgggacggag catcaagggg gcatgaggtg
    11761 aacgcgatac ggcaacgcgc cacggacgtg ccgcgctacg gcgacctgac cagcgcgcag
    11821 gtccgacagg ccatggacgg cgccacactc gtgtggccgg tgggcggcct cgaacagcac
    11881 ggcccccacc tgccgctctc cgtcgacatg gacatcccgg acgccctggc ccggcaggtg
    11941 gtcgcggagg ccggcggtct gctgctgccc ggccagccgt tctcggcgag gtcgctgccg
    12001 cagagcggcg gcggcctgca cttcccgggc accgtgcaca tcggcggcag cacgttcatc
    12061 gactacctca cggactgcct gacgtccctc gcccgcctcg gacccgcccg cctcgtcgtc
    12121 atcaacgggc actacgagaa cgagggcctg ctcttcgagg ccatcgacga ctgcgcccag
    12181 gccaccctgt tcccggacac cgaggtgctc gccttcagct ggtggagcct ggtcaccgag
    12241 gagtggctcg acgagcacat cccgcacttc ccgggctggc acgcggagca cgcgggcctg
    12301 accgagacga gcctgatgat gtacctccgc cccgacaccg tccgcgcgga acgccccggt
    12361 cacgacgcgc cgccgcccgc gggggtgtac cggcaccccg tcgacgtgga cgcgatctcg
    12421 aaccaagggg tgctgtcgtc cgccgtcggt gcctccgcgg agctggggga gagcctgttc
    12481 cggcacctgg tcgacggcgt cgtgcacctt ctcggcaagc cgccccggga ctcctgaaca
    12541 catcagtacg cgaccgcatg aacgccacct ccagggagct atgtcaatgc catcgaccag
    12601 gccgtacgag gactacgacg tgtgcgtcgt cgggcagggc tacgtcggcg tcacccttac
    12661 cgccgcactg ctgaccaccg gcagaagcgt gctcggctac gagaccaacc ccaaggtggc
    12721 ggccgaactc gcccggggcg tactcgaact ggccgagccc ggcgtcgagg aggagatcag
    12781 gggcgcggcc gcgagcggtg ccttcggtgt caccaccgac gtgcgcggcc ggaagctgcc
    12841 gccggtcgtc atcatctgcg tcggcacacc catcgagacc ggcggcacca cacccgacct
    12901 cagccatctg cgggccgcca ccgaggccat cgcgggcggc atcgacgaga cgaccctcgt
    12961 catcgtgcgc agcacggtgc cggtgggcac gtcacggagc ctggtgctgc ccatcctgag
    13021 cgagcgggtc cccgaaccgc tgatcgcgta ctgcccggag cgcaccatcc agggccaggc
    13081 gctggcggag ctcctctccc tgccgcagat cgtcggcggt ctgagcgacg aggcgggcaa
    13141 gcgggccgcc gagttcttcg gcacgctctc cgaccaggtc gtgcccgtct cctcgctgga
    13201 ggccgccgag ctcgtcaagc tggtgtgcaa ctgccacacc gacctgatct acggcttcgg
    13261 caacgaggtc gccctcatca ccgagaaact gggcctggac gcgcgcgagg tcatcgactc
    13321 cgccaacctc gactatccgc ggcccaacct gcacaagccg ggcttcgtgg gcggcagttg
    13381 cctcaccaag gacccgtacc tgctcgcgca ctcggtcgcg gcgtacgacc acgtcccgca
    13441 ggtgatcacc gccgcccgca ccctcaacga gtccatgccg cgcagggtcg gcgaacgcgt
    13501 cctggccgcg ctgtcggaac agggcgtcga cccggccgac gccaggatcc tgatctccgg
    13561 cttcgcctac aagggccgcc ccgagaccga cgacctgcgc ggagccccct acgaacggct
    13621 gctgccgttc ctccaggggc gggtcaagga gatcgtcggc cacgacttcg tggtgccggc
    13681 ggcccgcatc gagtcgctcg gcgtccggcc cgtcgacctc accgagggct tcaccggagc
    13741 ccacgcggcg attctcttga acgaccacgt gcgctatgga gacgtcgacg ccgccgacct
    13801 ggtggcgcgc atggcggaac cggcgctggt ctacgacacc tggcgggtcc tcccgtcctc
    13861 gacgaaggcg atgaggctcg gccgtgcgta agaagatcct gatcaccgga ggagccggct
    13921 tcatcggcct gcacctggcc cgccgtctcg ccgccagctg cgacgtgacc ctgctcgacg
    13981 acttcagcag gggccgctcc gacgcggaac tcgccgaact cctcggctcc gtcgaactcg
    14041 tcgagcacga cctgaccacg ccgattcccg acggactgct cggggacgac tacgccgagg
    14101 tctaccacct ggccgccgtc gtcggcgtcg ccgagtccaa cgacaacccg cgacgggtgc
    14161 tgcgcaccaa cctgctcacc accgtccacc tcctcgactg gttctcgggc ctgaccggcg
    14221 ccaccctctg cttcgcctcg tccagcgagg cctacgcggg cagcgtcgag gccggcgtcg
    14281 cgtccgtccc cacggacgag gacgtgccgc tgatggtccc cgacctgacg gtgccccgct
    14341 cctcgtacgg cttcagcaag atcaccggcg agctgctgtg ccgcacgtac gcgcgcaccc
    14401 acggcttcgc actgcgcatg gtccgcttcc acaacgtcta cgggccgcgc atggggtacg
    14461 accacgtgat cccgcagttc gtggagcggc tcctcggcgg cgccgacccc ttcgagatct
    14521 acggcgccga tcagacgcgc gcgttctgct acgtcgacga cgcggtcgac gccatcgtcg
    14581 cgctgaccgc gctgcccacc aaggagccgt tgctggtcaa cgtcggcaac gaccaggagg
    14641 aggtcctcat cagggatctg gcccggcacg tcttcgacgc cctggaccgc cacccggccc
    14701 tcgacgtcca cccggcgccc ccgctgtccc cggcccgccg cctccccgac atcgcccggc
    14761 tgcgcgaact gaccggatac agcccggcgg taccgttgtg cgaggggctg cgccgcacct
    14821 gcgagtggta cgcccggcac ccccgggccg ccgccgcgca cggaagcgga gcgtgagcgg
    14881 cgtgcgcgta cggtacgtcc accgcggcta cttcccggcg cgcgccgggg ccgaactgat
    14941 gacgcagtac ctcgccgcgt cgatgagccg cctcggctgg gaggccggga tctactcgaa
    15001 cccggtcgac gaggacaccg cggcgttcat gcgcggctcg ggcgtcagca tccagccgct
    15061 gcccgccaca cccgacgaca ccgaccgggc ggatctggtc cacgccatcg acgcgttcca
    15121 cccgcaggac atcgcggcgg gactcgacct ggcccgcgcc tggagcgtgc cgttcgccgt
    15181 caccccggcg tccgcccccg acgtctggcc ggaccgcgag acggtactcg acggatgccg
    15241 gaacgcggac gccgtcttcg ccctgtccga ggccgagcgc gacatgctcc gcgacgcggg
    15301 cgtcgacgga cgcagactgc acatcatcgg ccagggtccg cacctgcccg gcacccccga
    15361 ccccgaaggg ttccgccgcg cgcacggcat cgaagggccc atggtgctgt tcctggggcg
    15421 caagacgcgc tccaagggct acgtcacgct cctggaggcc accgaacaca tctggcgcga
    15481 ccaccccgac acgtcgttcg tgttcctcgg cccgcgctgg gacgacgact gcgccgagca
    15541 cttcgcccgg tacgcgggcc cgcgcgtcat cgagctcggc atggtcgacg aggacgtcaa
    15601 gcacagtgcc ctcgccgcct gcgaactgct gtgcgtgccc tccaccgtcg acctgttccc
    15661 gctcgtgtac gtcgaggcct gggcctgcgg caagcccgtc gtcgcgtcca ccttcctcgg
    15721 cagcgcggag atcgtcgccc acggccggga cggcctgctc gtccgcccca ccccccggac
    15781 ggtcgccgac gccgtcaacc ggctcctcgc cgacccggac gaacgacgcg ccatgggaga
    15841 acacggccac gacaaggtgc gccgcgaact cggctgggac gcggtcgccg accgggtcca
    15901 caccgtctac cgcacgctga ccgccgcccg gaagcaaacg gagaaagccc gatgagagca
    15961 gtggtactgg ccggtggcgt gggccggagg ttacggccgc acaccctgac catccccaaa
    16021 cccctcgtac ccatcgacgg cacaccgatc ctgcacatca tcctggcgca gctgcgcggt
    16081 gccggtttca cccacgtgtc gctctcgctc ggccaccggg cccacatgat cgaggcgagc
    16141 ttcaccggga accaatgggc cggcctcgaa ctggacttct tcctggagga ggagccgctg
    16201 ggcacggcgg gcccgctcgc gctgctgccg cccttcgagg actccacgct cgtgatgaac
    16261 gcggacctgc tcaccgacct cgacttcgcc gagctgatcg cacgccacaa gaagtcgcag
    16321 gccgccgcga ccgtcgcgct cagccgccag tacatcgaca tcgcgcacgg cgtggtcgaa
    16381 ctcgacgacg accgcgaggt gaccgacttc cgtgagaagc cccggctcag cttcctggtc
    16441 aacgccggca tctacgtact cgaaccgtcc ctgctgcggc tgctcacacc ccgcgtccgg
    16501 gacgacatgc ccgccctcct cgaccgcgcc cgcaccgagg gcgaacgcgt cgagggccat
    16561 gtcatcgaag gggactggca cgacatcggc acgcccgagc agctgaaccg ggccgccgcg
    16621 gccttccgca acgaccgcgc ccgctacctg ggccgcggcg cggcggccgt cctcggcgcg
    16681 ggcaccggag cgttccagga ggtgggatcc ggatgacggc gttcgacatc gcgctgtacc
    16741 gcccgcacat cggacaggcc gagatcgacg cggtcaccca ggtcctgcgc tccggctggc
    16801 tctcgaacgg gcccgtcacc gaggacttcg aggccaagta cgccgccgcg ctcggcgtcg
    16861 ggtccgccgt cgccgtcagc agcggcaccg ccgccttgca cctggccttc ctgagcctgg
    16921 acctcggtcc gggcgacgag gtcgtcctgc cctcgctgaa cttcgtgtcg gccgccgcga
    16981 ccgtcgccct gtccggcgcc acccccgtct tcgccgacgt caagggcgcg cacgacctgt
    17041 ccatcgaccc cgaggacgcc gcccgccgcg tcactccgcg cacccgggcg atcgtcgcca
    17101 tgcactacgg cggccacccc gccgacctga cggctctcgc ccgcctggcc cgcacccacg
    17161 gcgtcgccct cgtcgaggac tgcgcccacg cccccgtcac cgactcgccc cacggcatgc
    17221 tcggcacggt cggcgacatc ggctgcttca gcttcttcgc cacgaagaac ctggccatgg
    17281 gggagggcgg catggtcgtc gcccgcgacc ccgccgtcgc cgaccgcatc cgacggctgc
    17341 gctcgcacgc cctgaccgtc agcgcccagc agcgccacca cggtggctcc tccctgtacg
    17401 acgtcgacac cctcggcctc aactaccggc ccacggagat cggctgcgcc ctcggccgcg
    17461 tacagctcga agccctcccc gcgggccagg tccgtcggca ggaagcggtc cagatgtacc
    17521 gcgagcagct ggccccgctg cccggcatca cggtgccgta cgcggaccgg ccggtggagg
    17581 agagcgccca ccacctgttc gcggtggtgc tgcccgcggg caccgaccgc gacgcgctgc
    17641 aggacaaact gcgtgccgcc cggatccaga gcggtgtcca ctatccgccc acgcacctgt
    17701 tctccgccta ccagcggcgc ggcaggggag ggccgtgccg gctccccgtc accgaggacg
    17761 tgatggcgcg tcagctctcc ctgcccctcc accccggcat cggcaaggac gaggtgcggc
    17821 aggtcgtcga ggcggtgagc gacgcgtggc cggagacacc gtgagcggcg ggcgcgtcac
    17881 gttcgccgac ggcgccctgt accgggacgg gcacccgtac gtcagtgtcg gcgtcaacta
    17941 tcacccctcg ccgaccgggt gcgagtactg gcgggagtgg gacggcgacc gcatcgacga
    18001 cgacttccgg cggatggcgg cggagggcct gaacaccgtg cggttcttcg tcttctgggc
    18061 cgacttcgaa cccaaggaag gcgtctacga ctccacggcg acggaccggc tgcgggagct
    18121 cgtccggacg gcgcggcggc acggcctgct gtgcctgccc tccctcctga cgatctggat
    18181 gaacggccag cggttcgacc tgccgtggcg cgacggccgc gacctgtggc gcgacccgga
    18241 cctgcgcgag cggcaacgcg ccttcgtcca ccacatcgcc gccgagctcc gggacgagcc
    18301 gaacgtcctc gcgtacgacc tgggcgacga ggtgatccac gtcgactcca ggtcgtccgc
    18361 ctccctcggg cccgacgagg tgcgcgcgtg gtggggaatg ctcgcctcgt cgatccgcga
    18421 cgccgacccg gacgccctgg tcctccaggc caacgagccc tccgcggtcc tcggcggcca
    18481 cgccttccgc cccgagcacg ccgacagcct cgacatggtg gggctgcacg gcttcccggt
    18541 gtggacgccg ttccacgtcg agtccgtcgc ggcccgcaag gccaccgcct tcgtgcccta
    18601 cctggtgcgg cggggcagcg cccaccggcc ggtctacgtc gacgagctgg gcagctacgg
    18661 ctgcgacggg accaccgccg cgcggtacct gcgggccgcc tcccactccg cgttcgcggc
    18721 gggtgccgtc ggcaccgccg tctggtgctg gcaggacttc accaccgagc gcaagcccta
    18781 cgcgctgcgg cccaacgagc ggcgcgtcgg cctcctggac gcggacggcg gcgagaagcc
    18841 cgtcctcgcc gagtaccggg agttcatccg gcgcgtgacc ggggaactcg ccgggttcag
    18901 gccactgccc gccccggtgg gcgtgttcgt ccccgaggcc gaggagcagg aggaagccgg
    18961 atacctgacg ccctcgggca gcgacgcacc cgccgccttc tacgcccacc tcctccttca
    19021 acaggcccat ctgccctatg agttcactgg acgcgacccg gagctggagc ggcacgcgct
    19081 ggtgatctgc ccctccgcgc gtacgctgtc gctgccggac cgccgccgcc tggcccggta
    19141 cgtcagcgcc gggggagtgc tgctgtactc caccggcagc ctcctcgacg ccgccggcga
    19201 cgaggacctc ttcggcatcc gcgtacggga cttcacacgc gccgacgaca cccacgccga
    19261 gttcacctgg gcgggcacgc gcttcccgct gcgctgggac acgggcccga tcccggtgat
    19321 cgacacggcg ggcgccgaga cactggccgc gttcgccgac ggttcacccg ccctgacccg
    19381 ccaccgcctc ggcgaaggca gcgtctacta cctcaacgcc cccctggagg cgcagctcaa
    19441 cgccccctac cgcctggacg aaaccgactg gcaccggctg tacgaagcgg tcgccgagca
    19501 agcgggcgtc cgcgcgccgc tcaccgcgga ggacccgtcg gtggagacca cggtcctcgg
    19561 acgcggcgac gaacgctgcg gcgttgtcat caaccacgcc cccgaaccgg tggacacggt
    19621 cctgcggcgc cacacggcgg acggcaccac ggagagcgag aagccgctcc acctcgaacc
    19681 caaggacgta cgcctgctgt tctggcacgg cgacgagccg cagcggcccg aggggcggca
    19741 gccgtgatca tcgacgccca cgtgcacgcg ggggagtact accgccacta cacggcccgc
    19801 ttcgccgaac agatgacggc caccaccgac ctggcgcccg aggacctcac cgcgcccgag
    19861 gccaagctgc tcgccgagat ggacgccgcg ggcgtcgacc gcgtcttcct gctcgccttc
    19921 gacgtgcggc gcgtcgaggg gttctcggtg ccgaacgagt tcgtcgccga cctgtgcgcc
    19981 cgccaccccg accgcctgac gggcttcgcc tccgtggacg cgggcacccc cggcgcggcg
    20041 gagcgcctgc gcgaggccgt caccgatctg ggcctgcgcg gactgaagac agccccctgc
    20101 tacctgcgca tgtcacccgc cgaccgccgg tggtacgacg tctacgagac cgccgcggaa
    20161 ctggacatcc ccgtcctgat ccacaccggc tacacgccct cccgcaacgc ggccccccgc
    20221 ttcttctccc cgctcctcgt cgaacaggtg gccaaggact tccccggcct gaaggtgatc
    20281 ctggcccacc tcggcacccc ttggaccggc ccctgcgtcg aactgctcgc ccgacacccg
    20341 gacctctacg cggacctgtc catcttcggc tcctaccagc cgcccgccgt cgtggccagg
    20401 gccctggccc acgcccgcga ccgcggcgtc ctcgaccggc tcctgtgggg caccgacttc
    20461 cccttcgcgt ccatgaccgg gtccgtggcc cgcacggcgg aactggcccg cgaccccggg
    20521 ccgtggcccg acggcagcga cccgctctca ccgcgtgagt acgaggacct catgggcggc
    20581 acggcggcgc ggctgctcgc ccccaccgca ccgcacgctg ctccggtccc cccaccccac
    20641 cgatgacttg aggtgtcatg accttcgtcc acggatacga gttcgacgcg atgtcgcgcc
    20701 gccccctgta cggcgacgtc acccagcgtc tggtcgacat ctgcgaagcc ccggagggcg
    20761 gcgtcgtcgc cgacgtcgga tgcggctcgg gcctcgccac cgaactcctc ctggaacgct
    20821 ccgcgcacgt cggctccatc atcggcatcg acccgtcgga acacgaactc accatcgcgc
    20881 gagcccggtt gaccgacccc aaggtgcgct tcgtgcaagg gcgcgcccag gacgtcgagt
    20941 ccctgaccgg accggtggac gtcgccgtcc tgagcaacgt catgcaccag atcccggccg
    21001 acgagcgcgg cgcggtgctc gccgggtgtc accgcctcct cgccccgggc ggacgctgcg
    21061 ccctgaacac cctcttctac gagggggccg tgctccccgg gacccggccc ttctacaccc
    21121 actggctgcg cgccacccgc gccgtcctgc gggaccgcgg cacggacctc gtcctcgtgc
    21181 gcgagcggcc cgtggcgatg cagacgctca caccgcgaca gcacgaagac ctcttcgccg
    21241 acgcggggtt ctcccagacc aagtccgagg aggccgagta cacgtggacg ctcgcagact
    21301 gggaggcgct ctgcgcgtac tcggtgttca tcgagggggc caccggcatc agtgacctcg
    21361 ccctcggctc cgacgcgctg atccggggcc tgcgcaccac cttcgaggaa ctggaactga
    21421 gcggggtgcc ccggcgctgg ctgttcacgt ggggcgtcaa atgagtaccg ccccgcgcgg
    21481 cgacgccccg ctctcgtacg cccagcaggg catgtggttc ctggagcgcc gcgccggaca
    21541 cgcccgccac accgtcgccg tgaccttccg tctcgtcggc gacctcgacg cggcggccct
    21601 gcgggcggcc atcgaggacg tcgtcgaccg gcacgaggcg ctgcgcacct gcttccccgt
    21661 cgtggccggc ctccccgtcc agcgcgtggt cccacgggtc gaggtgccgc tgcccctgac
    21721 ggatctcacc gcgctccccg aggcggaacg cgaggcggcg gcggcacggt tcctggcgga
    21781 ggacctgcgg cgccccttcg acctggtccg cgggcccgtg gtgcgggcgg cgctgctcgg
    21841 cctcgggccg cgcgagcaca tcctccgcgt ctcctcgcac cacctggtct ccgacgcctg
    21901 gtcgtggtgg gtggtgatcc tccgggaact ggagcagctc tacaccgcac acctgcacgg
    21961 gcgcccctcg cccctcccgc cggtgcccgc ccagtacggg gacttcgcgc gacggcagca
    22021 tgagtggctc gacggtccgg ccggtgcgaa acaactcgcc tactggaagg aggtgctggc
    22081 gaccgcgtcc cccttgcctc cgctcaccct ggcatctcct ccggcatccc cctcggggcc
    22141 tccctcggcg cctccggagg ccgaagaacc ctcgcgcacc cagtggacgg ccgttcccca
    22201 gcccctgtac gaccggctgc aagcgaccgc acggcgtgag cacgtctccc tcttcatgct
    22261 gctgctcgcc gcctccaagc gcatgctgcg tcgccatgtc gacaccgacg acatcctcgt
    22321 gggcacgcgc ggcggattcc gcagcagcgc cgagttcgag aaggccgtcg gcctcttcgt
    22381 gaacctgctg ccggtacgga cccacgtggc cgcggacgcg gacttccgcg acctgctgca
    22441 ccgggtccgc cggaacctga tcggcgccta cacccaccgt gacatgccgt tcgagcggct
    22501 cgtgcaggtc ctcgggctgt ggcggcccgg cttccggccg gtgatcggcg cctgcgtcac
    22561 cttccagacc gcaccggagg tgccgcccgc cctcgaaggc ctcgacacga cgcccatcaa
    22621 ccacgacccc ttctcggcgc accccttgga cctcggcttc ttcgaggagg cgggcgcact
    22681 gcgcgtcctg ctggcatacg acccggccca gtacgacgac aaggccgccg cacgcctcct
    22741 cgacgacctg cacgaggagc tcgacgcagg ctgccgtgaa ctggaggacg catgagagcg
    22801 ctgcgatggc acggcacacg ccgcgcggag gtcgcggacg acgtcgccat gccccgtgtc
    22861 gaggagcccc gggacgccgt cgtccgggtc gtgcgcagcg cgatctgcgg caccgacctc
    22921 cacccgtacc gcggcgagat cgacggcttc ccggcgggaa cggtcacggg ccacgagttc
    22981 accggcgtgg tcgaggagac cggccccgag gtacgcggcc tccgcgccgg tgaccgggtc
    23041 gtcgcctcgg acatcatcgc gtgcgggcac tgccggtcct gccgccacgg ctggcactac
    23101 cagtgcgacc gggtgggcct gttcggctat gcgaccgtgg tgggcacgcg ggcctacgcg
    23161 ggcgggcacg ccgagttcgt gcgggtgccg ttcgccgaca ccgtgctgtt cccgatcccc
    23221 gacgacgtcg gcgacgagcg ggcgctgttc gtcggcgacg tcctcgccac cgggtacgcg
    23281 tgcgccgtgg gcgccggggt gcgtcccggg gacacggtgg cggtggtcgg ctgcgggccc
    23341 gtgggcctgc tggccctgga ggtcgcctgg ctgctcggtg ccgccagggt gctcgccgtc
    23401 gacccgctgg agagccggcg gaaactggcc gccgaacggg gcgcgtaccc ggtgccggcg
    23461 gcgcccgacg tggcacggca ggtcgccgac ctgaccgagg gacgtggcgc ggacgccgtc
    23521 ctggaggccg tgggcaccga cgcgtcgctg ctgaccgcgc tgaacgtcgt gcgcccgcgc
    23581 gggacggtct gcgccgtggg cgcccacgcc tccgacgcca tgcccatgcc gacccggctc
    23641 gcgttcgcca aggaggtcac gctgcgcttc gcggtcggcg accccgtcgg cgacttcgag
    23701 cccctgatga acctggtgcg cggtggccgc gtcgacccga cgtacctcat ctcgcaccgg
    23761 atgccgctgt cggaggccgc cgagggcttc cggctcttcg acgcgggcga agccagcaag
    23821 gtggtgctga tcccatgacg gcgccaccgt cccggacgcc cacgtccacc gcggaccaac
    23881 cacacatcag ccgcacatgg ccgcacatca agacacctgg aggaacagtg acggacaacc
    23941 tggccgctca gtccccgtcc acgtcgggcg acgcggaagc ggcggcggaa gtggtgcgca
    24001 ggatctgggc gcaggtcctg gaggtgagcc ccgactccgt cgacgtccac cacagcgact
    24061 tcttcgagat gggcggctat tcgctcctcg cgctgcaggc catcgggagg atcctggcgg
    24121 agtacggggt cgacgaggtg gaagcggtgg agtgggaggg cgaactcctc aaccgcctct
    24181 tcgagaacgc gacgccgatg acacaggcgg agttcctcgc ggagaagggc tgcggcacgc
    24241 cgagtgcggc gaactccacg cacgtgtgag cagcggcatg tgagccggga aagggcgtcg
    24301 ggccggggca accgccccgg cccgacgccc tttcccgtgc tggcggcaga aggtcacccc
    24361 actgcggccg ccctcttctg accggcaccg gccgcggtga ccgcggcgtt gacggcccgg
    24421 tgtgcctccg tggcgatgcg ttcgccgtcc gccgcgctcc tggcgcacac gacgatgccc
    24481 agcgagggcc ggtgtcccgt gagggcgcgg acggtcgacg ggtaggcacg gacgccgcgc
    24541 gcccacagtt cgtcgaagac gggccggatg tgctcctcgt aggacaccgg gcccgacagt
    24601 cgcaagggca gcgcgtcgtt gacgtacgcg accggcacct cgtcggccca ccgttccgcg
    24661 agggcgacgg cgtgcatggc gccggagcgc cgggcgttga tctcggtgac gtagagcgcg
    24721 tcatcgaggc cgcggaggca gtcgaccgtc atccagcccc ggtagccgag ggattgcgcg
    24781 aacgtgtgga cggcggtgcc gagcgcggcg agccgttcct cgaggtccgg gtcgaggact
    24841 ccgggcccga gtgcgaggct gcggtaccgc agtccgtcga cgccgagcat gctgtactcc
    24901 atgcgcggca ccgcgccctc gtcgacgagg acgtccacgg cggggcagtc ggtgccgtgc
    24961 gcgatgtagt cctgcacggt gagcgggaac gtgccgaaga acggctcgcg gcgcagggtc
    25021 tgccagaagc gccgtacggt gccgtcggca tcgccccgcg cgacggcgga gccgtaaccc
    25081 cccactccgt acatgctctt gaccacggcg cgaccgccgt tgcccacgat cgtggtgacc
    25141 gcgcccttga gctgttccca gctggtgacg gagatgccgc gcggcacgcg gaatccgggg
    25201 atgtgcgagg cgaggtcgac acagcacagc ttggattcca ggtactcgta cgaccagtag
    25261 tgctccggtc ccgccacgtc caggcgcacc tcccgcccct gactgcggag cacggaggcg
    25321 agggagtaca ggtccggcga cgcgccgaag gacaggagcc gcacctcccg caccccgtcg
    25381 gtcgcggcgg cgagggcggc cagcgcccgg tcgtcgtcga gcaggtcgcg gatcagacgg
    25441 ccggtgcgcg gcaacgggga tatgacgtca ggcacggaac tgccgagacc ggcgtggacg
    25501 tgcgtcagcc actcctggga gtagccggcg ggcagcacga gcacgcggtc cccggcactc
    25561 cagaacacac actgatcggt gtatcccgtg ccgtgctcga cgaggtcgtt ttccacaccc
    25621 gggtcgaaat ccagcagttc gcgtttcagg ttgaactcga cgacgttcgg gaccaccaga
    25681 tcaatggtgt cgggcatgct ttcctgcctt ctttcccagc ggctctcaac ggcccctagt
    25741 agctcgaatg cacaccggga gtgagcagat gcttctccgg cccttgcagg gccggagaga
    25801 agacgcacat cagcgtcatg ccgtgttccg agcggagtat gtgcggctcg cccatgcccg
    25861 gggcgtacag cattcccggc ttgatgtcga acaggccgtc cgccgtctcc acggagccgg
    25921 cgccggacac gcagtagcag acctcttggt ggttgtcgta ccggaggtac gactcgctgc
    25981 cgggctgtac gtacgtctcg gtcaggctga aacccaattc atcggcctga acgagcagcc
    26041 ttcggctcgt tccgttgccc cagtccacgt cgtattcgct tccgacgaca tcttcaaccg
    26101 agcgaaccag caa
//
