BGC0002045 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002045 (Streptomonospora sp. PA3)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T2PKS	1	72,501	High	persiamycin A	PKS:Type II

BGC0002045 - Region 1 - T2PKS

Download region GenBank file

Download region SVG

Location: 1 - 72,501 nt. (total: 72,501 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 72,502
Label		BGC0002045

Tailoring functions

Oxidoreductases: dehydrogenase

FZ103_09765: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

FZ103_09900: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: aminotransferase carboxylase glycosyltransferase halogenase methyltransferase transferase

FZ103_09795: O-methyltransferase

smcogs: SMCOG1042: O-methyltransferase

FZ103_09825: DegT/DnrJ/EryC1/StrS aminotransferase

smcogs: SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase

FZ103_09830: glycosyltransferase, MGT family

smcogs: SMCOG1062: glycosyltransferase, MGT family

FZ103_09835: glucose-1-phosphate adenylyl/thymidylyltransferase

smcogs: SMCOG1064: glucose-1-phosphate adenylyl/thymidylyltransferase

FZ103_09860: acetyl-CoA carboxylase biotin carboxylase

smcogs: SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

FZ103_09885: acetyl-CoA carboxylase, carboxyl transferase,

smcogs: SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,

FZ103_09905: conventional flavin-dependent halogenase

halogenases: conventional flavin-dependent halogenase
smcogs: SMCOG1119: halogenase

Hydrolases: hydrolase

FZ103_09920: alpha/beta hydrolase fold protein

smcogs: SMCOG1036: alpha/beta hydrolase fold protein

Lyases: cyclase dehydratase

FZ103_09810: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

FZ103_09855: Polyketide synthesis cyclase

smcogs: SMCOG1225: Polyketide synthesis cyclase

FZ103_09870: cyclase/dehydrase

smcogs: SMCOG1128: cyclase/dehydrase

Ligases: synthase

FZ103_09840: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

FZ103_09845: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002045.3	1.00	PKS	persiamycin A	Streptomonospora sp. PA3
BGC0002341.2	0.77	other (other)	3,5-dibromo-p-anisic acid	Planctomycetales bacterium 10988
BGC0002608.2	0.76	NRPS, PKS	ochratoxin A	Aspergillus steynii
BGC0000231.5	0.62	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0000272.3	0.62	PKS	spore pigment	Streptomyces collinus
BGC0000234.5	0.60	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001723.5	0.59	PKS	oviedomycin	Streptomyces antibioticus
BGC0000271.5	0.57	PKS	spore pigment	Streptomyces avermitilis
BGC0001197.5	0.56	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0001817.5	0.56	other (other)	vancosamine	Streptomyces sp. WAC2288

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002045.3	1.00	PKS	persiamycin A	Streptomonospora sp. PA3
BGC0002341.2	0.77	other (other)	3,5-dibromo-p-anisic acid	Planctomycetales bacterium 10988
BGC0002608.2	0.76	NRPS, PKS	ochratoxin A	Aspergillus steynii
BGC0000231.5	0.62	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0000272.3	0.62	PKS	spore pigment	Streptomyces collinus
BGC0000234.5	0.60	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001723.5	0.59	PKS	oviedomycin	Streptomyces antibioticus
BGC0000271.5	0.57	PKS	spore pigment	Streptomyces avermitilis
BGC0001197.5	0.56	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0001817.5	0.56	other (other)	vancosamine	Streptomyces sp. WAC2288

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 72501
Starter unit(s):: acetyl-CoA (Score: 0.0; E-value: 0)
Malonyl elongations:: 8|9 (Score: 673.5; E-value: 2e-205)
Product class(es):: tetracenomycin
Product molecular weight(s):: acetyl-CoA_8: 550 Da
acetyl-CoA_9: 592 Da

FZ103_09765: KR (Score: 132.8; E-value: 4e-41)
FZ103_09795: MET C10 (Score: 427.7; E-value: 6.1e-131)
FZ103_09830: GT (Score: 344.4; E-value: 2.6e-105)
FZ103_09840: CLF 8|9 (Score: 673.5; E-value: 2e-205)
FZ103_09845: KS (Score: 768.9; E-value: 2.7e-234)
FZ103_09855: CYC C4-C21/C2-C23|C2-C19 (Score: 110.8; E-value: 6.9e-35)
FZ103_09870: CYC C9-C14 (Score: 252.3; E-value: 3e-78)
FZ103_09875: CYC C5-C18 (Score: 189.2; E-value: 5.8e-59)
FZ103_09880: ACP (Score: 105.7; E-value: 2.1e-33)
FZ103_09900: KR (Score: 155.0; E-value: 6.9e-48)
FZ103_09905: HAL (Score: 401.9; E-value: 7.9e-123)