BGC0002047: brasiliquinone A biosynthetic gene cluster from Nocardia brasiliensis
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 14,165 nt. (total: 14,165 nt).
This entry is originally from NCBI GenBank MT023106.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002047
Short description brasiliquinone A biosynthetic gene cluster from Nocardia brasiliensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MT023106.1
1 - 14165
via Heterologous expression
Compounds
  • brasiliquinone A
  • brasiliquinone B
Species Nocardia brasiliensis [taxonomy]
References
Chemical products information
brasiliquinone A Evidence:
Copy SMILES
Chemical database entries
NPAtlas
brasiliquinone B Evidence:
Copy SMILES
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QHZ32172.1
  • brqN
 251 - 577 (+) tetracenomycin F2 cyclase
    copy AA seq
    copy Nt seq
    • QHZ32173.1
    • brqA
    		 574 - 1845 (+) polyketide putative beta-ketoacyl synthase
      copy AA seq
      copy Nt seq
      • QHZ32174.1
      • brqB
      		 1854 - 3041 (+) polyketide putative beta-ketoacyl synthase 2
        copy AA seq
        copy Nt seq
        • QHZ32175.1
        • brqC
        		 3054 - 3311 (+) acyl carrier protein
          copy AA seq
          copy Nt seq
          • QHZ32176.1
          • brqD
          		 3324 - 4109 (+) putative ketoacyl reductase
            copy AA seq
            copy Nt seq
            • QHZ32177.1
            • brqE
            		 4131 - 5078 (+) putative polyketide cyclase
              copy AA seq
              copy Nt seq
              • QHZ32178.1
              • brqF
              		 5082 - 6536 (+) anhydrotetracycline monooxygenase
                copy AA seq
                copy Nt seq
                • QHZ32179.1
                • brqG
                		 6565 - 8076 (+) anhydrotetracycline monooxygenase
                  copy AA seq
                  copy Nt seq
                  • QHZ32180.1
                  • brqH
                  		 8073 - 8984 (+) 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase
                    copy AA seq
                    copy Nt seq
                    • QHZ32181.1
                    • brqI
                    		 9016 - 9885 (+) glucose-1-phosphate thymidylyltransferase 1
                      copy AA seq
                      copy Nt seq
                      • QHZ32182.1
                      • brqJ
                      		 9942 - 11063 (+) dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
                        copy AA seq
                        copy Nt seq
                        • QHZ32183.1
                        • brqK
                        		 11060 - 12442 (+) NDP-hexose 2,3-dehydratase
                          copy AA seq
                          copy Nt seq
                          • QHZ32184.1
                          • brqL
                          		 12435 - 12866 (+) hypothetical protein
                            copy AA seq
                            copy Nt seq
                            • QHZ32185.1
                            • brqM
                            		 12872 - 13603 (-) sensory transduction protein regX3
                              copy AA seq
                              copy Nt seq
                              Biosynthesis information
                              Annotation changelog

                              Entry version: next

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2024-08-10
                              MIBiG v4 annotathon
                              • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 1

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-09-15
                              Entry added
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              Detailed domain annotation
                              Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                              A domain glossary is available here, and an explanation of the visualisation is available here.
                              Selected features only
                              Show module domains
                              Similar known gene clusters from MIBiG 4.0
                              Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                              Click on reference genes to show details of similarities to genes within the current region.
                              Click on an accession to open that entry in the MiBIG database.