BGC0002051: antipain biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 13,500 nt. (total: 13,500 nt).
This entry is originally from NCBI GenBank MT149901.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002051
Short description antipain biosynthetic gene cluster from Streptomyces sp.
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: MT149901.1
Compounds
  • antipain
Species Streptomyces sp. [taxonomy]
References
Chemical products information
antipain
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • NAI38-460
  • QOE83921.1
  • efflux_transporter
 163 - 1470 (+) putative multidrug-efflux transporter
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  • NAI38-461
  • QOE83922.1
  • dhbF
 1588 - 2883 (+) dimodular nonribosomal peptide synthase
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  • NAI38-462
  • QOE83923.1
  • tycC
 3033 - 6227 (+) tyrocidine synthase 3
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  • NAI38-463
  • QOE83924.1
  • lgrD
 6224 - 8167 (+) linear gramicidin synthase subunit D
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  • NAI38-464
  • QOE83925.1
  • lgrB_1
 8169 - 10088 (+) linear gramicidin synthase subunit B
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  • NAI38-465
  • QOE83926.1
  • lgrB_2
 10078 - 12936 (+) linear gramicidin synthase subunit B
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NRP-specific information
Subclass N/A
Cyclic? no
Release type
  • Reductive release
NRP-synthases
Gene Modules
tycC
Module ?
Specificity: arginine
Evidence for specificity:
  • Structure-based inference
lgrD
Module ?
Specificity: phenylalanine
Evidence for specificity:
  • Structure-based inference
lgrB_1
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: LOOLDPJUN4VZBEJ3W5R2EHIG, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
  • Added version to NCBI accession
  • Added NRP substrate specificities
Detailed domain annotation
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