LOCUS       BGC0002069             10624 bp    DNA     linear   BCT 03-JUN-2019
DEFINITION  Pseudomonas fluorescens strain HKI0874 c_000000000015, whole genome
            shotgun sequence.
ACCESSION   BGC0002069
VERSION     BGC0002069
KEYWORDS    .
SOURCE      Pseudomonas fluorescens
  ORGANISM  Pseudomonas fluorescens
            Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
COMMENT     Bacteria and source DNA available from JMRC, HKI Jena.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 06:28:45
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 26881
            Orig. end    :: 37505
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..3651
                     /locus_tag="FGA82_11240"
     CDS             1..3651
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007915019.1"
                     /locus_tag="FGA82_11240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="indolepyruvate ferredoxin oxidoreductase family
                     protein"
                     /protein_id="TMU80018.1"
                     /transl_table=11
                     /translation="MYLDSIDSERQRLQPDKLATAEAQAALSRIERYDSRSMYCREHAL
                     PNERIFLSGQQALVRLLLSQAELDRSNGIRTAGFVSGYRGSPLGGVDRELVKAKAVLES
                     ANIRFLPAINEDLAATALIGTQRVESDPQRLYDGVFGMWYGKGPGVDRSGDAIKHGSSY
                     GSSPNGGVLVVTGDDHGCVSSSMSHQSDRTLIAWGLPVIHPAGLDDYERCGLWGWALSR
                     VSGLWVGFKAITETVEATASVESIPLPEFVTPEINPGPDGLHWRWPDLPGMQIERRTAF
                     KFDAARAFALANPIDTAVTAPARPTLVIGAVGKAYGDVRQALQQCGISLEQLENAGVAL
                     LKINLVYPLSPVLEAWTLRAGKVLIIEEKQAIVEEQLKQKYYNAAHDQRAVIIGKTDEH
                     GQPLISDHEELRPSRIAAVLKQRLQGLGIDLGLPDFWRLPSVSRMEDWIRRTPYLCSGC
                     PHNTSTQVPKGSEARLGIGCHAMAARMPERSTTGSVQMGGEGVDWLGQAPFVQTPHIFQ
                     NIGDGTFFHSGFLAVRQGIAAGATITYKLLYNDAVAMTGGQPIDGKLTVKKAVELLKAE
                     GAQRIVVVADDLQRYQAHDSLPQGIEVFHREKLEEVQLQLRDTRGVSVLIFDQVCAVEG
                     RRRKKQLPAPLVKTEVVINEAVCEGCGDCQVKSNCLSVIPVQTPFGAKRRIDPHSCNTD
                     LSCIKGFCPSFVTVTGKPRQRPRKLADSAQVLARAEALALALPHVARSLDLPYEMLLVG
                     VGGTGVVTVARAIAMAAHLDGRAVSVLDFTGFAQKGGAVLSHIRLAGDADALHQHRIDI
                     GGADLLLAADLVVASEDDALATLRPDKTVVIANSALTQTGAMLRNTRLGIETDAIQTFL
                     KQKVGAEHFHSLDAGELATSLVSPMQANMLLLGYAWQKGTIPVSLPALKKAIDLAGSAA
                     TNHLAFAWGRLWAQDSAFVAPYLEQPVDAVSTIAIRDISDMRGRRESLEQMVDHRSEFL
                     SGYQNAAYAARYRKVIEQLRALPAAGDDSALTQAVTRNLFKLMAYKDEYEVARLLTTRS
                     FTDSLKARFDGGIRLKFHFALPLLRKNQASTGEPKKIALSGWILPLLKVLAKGRVLRNT
                     RFDPLGFSAERREERRLLNDYEQTLQRLLPKLNSENLSAFVAWANLPDSIRGYGHVKER
                     SIAAARLREKELIEQILADKPVIHGVESWQPSTVIARQLSEEERDVMEAS"
     subregion       1..10624
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="Other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..10624
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            3715..4779
                     /locus_tag="FGA82_11245"
     CDS             3715..4779
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007915021.1"
                     /locus_tag="FGA82_11245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="A-factor biosynthesis protein"
                     /protein_id="TMU80019.1"
                     /transl_table=11
                     /translation="MNNDSIAPDLLHKGSADDVLIGAPRDALPLYVNETLIEANGHNPL
                     VGNYAAGANQPRRFEITPELQKNSRMGGDDEWNRLRALPYQIVAAQLEAAGIRSDSLEA
                     AVAALCESIPAIRRASSFRFINNADNYFFYRKAHEHVPGTMFIEAARQAVYHHLYHHTD
                     HARGAVTVSVNELNASFFAYAELMYPIELVVDNMTPSDATSPKKIHLRVAFYQRQTLFA
                     TVDTKATVIDMPLFEKTRNIFIYCNDWFAPLQPLKLACTISDAQGRKVEVQLLGLGKSG
                     CVTTTADMSEPVTLQIVYEGKLSFTAGIRPVGQGKHSSWEFAEVDFNGLQVISDMIKRG
                     FVHLDEPALAALQQ"
     gene            4776..5957
                     /locus_tag="FGA82_11250"
     CDS             4776..5957
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     225.2; E-value: 1.9e-68)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007915023.1"
                     /locus_tag="FGA82_11250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="TMU80020.1"
                     /transl_table=11
                     /translation="MIVATPTFQAATRTLHFGAQAVAKNRLYFSSLGMDLCDEHGFPQP
                     AFFSVYQALMDGGAGFGFLGNASVDADARYNSRGLRLTSAAHAQALRPLFEAARARGFP
                     LGVQLQHYGPQSLPSKQGIILTPSAIASPTILSAYPEARAVAMSEAQIQRCIEQFCVAA
                     RYAQQAGATLIQLQASNGYLISSFLSPKTNRRVDDWGGTPLKRARLLLSIVDGIRQATD
                     HKVAVTVRLGMDDGLGAEGQHAALLGDVVAALEASGVAAITCSLGISETFRFFFKNAGQ
                     ALAMSREGCRYLKRFVRIPLGFTGSVADVAQADEIIASGDADFVGFGRAMLADNDFVAK
                     QLAGRADQLNRCRGDAFCFRDKKEPMAERVYCCVNPAYRRPEQLQQYYEENLK"
     gene            5954..6727
                     /locus_tag="FGA82_11255"
     CDS             5954..6727
                     /NRPS_PKS="Domain: PKS_KR (7-164). E-value: 8.4e-14. Score:
                     43.7. Matches aSDomain:
                     nrpspksdomains_FGA82_11255_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     198.8; E-value: 1.7e-60)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007915024.1"
                     /locus_tag="FGA82_11255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="TMU80021.1"
                     /sec_met_domain="adh_short (E-value: 3.5e-37, bitscore:
                     117.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTAKIALVVGGTRGIGFDVSQKLIEAGCICYITGRNEDDGLTA
                     QSRLGENCTFIRSDVTDESSVIELFRLINDKHGRLDLAVNNAGVTSKHAPIRDMDFADW
                     KRVLEINLLGPLLLLKHETNLISKHAGGSIVNVSSCAGLLGVAKQSAYSTSKAALNMLT
                     QVCAIECAEEALPERHSIRVNAVCPGPTLGGMNSEERLKANPESTRHKLQVTAMKRFAN
                     PGEISAAILWLLSDASSFVTGTVMPVDGGFSAGKF"
     aSDomain        5975..6445
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGA82_11255_PKS_KR.1"
                     /evalue="8.40E-14"
                     /label="FGA82_11255_PKS_KR.1"
                     /locus_tag="FGA82_11255"
                     /protein_end="164"
                     /protein_start="7"
                     /score="43.7"
                     /tool="antismash"
                     /translation="ALVVGGTRGIGFDVSQKLIEAGCICYITGRNEDDGLTAQSRLGEN
                     CTFIRSDVTDESSVIELFRLINDKHGRLDLAVNNAGVTSKHAPIRDMDFADWKRVLEIN
                     LLGPLLLLKHETNLISKHAGGSIVNVSSCAGLLGVAKQSAYSTSKAALNMLTQ"
     CDS_motif       5978..6040
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGA82_11255_0001"
                     /evalue="1.20E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="FGA82_11255"
                     /protein_end="29"
                     /protein_start="8"
                     /score="14.7"
                     /tool="antismash"
                     /translation="LVVGGTRGIGFDVSQKLIEAG"
     gene            6727..7545
                     /locus_tag="FGA82_11260"
     CDS             6727..7545
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     71.9; E-value: 9.8e-22)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223960.1"
                     /locus_tag="FGA82_11260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="TMU80022.1"
                     /transl_table=11
                     /translation="MHTVKRNPTAGAREKASHRVFITGVSSGIGEALALLHLQNGHTVF
                     GTSRRQPYGLMDYPDFHFRPFDLSRPSAMDELFEDNFASVLEQGVDRVFLNAGVSGNVP
                     GRAAEFSLDELQHVLNVNVLANKAMLDLVLSSSRRPTTCVLSASMAGVRFRAGTLPYSL
                     SKAALAALGGVYAEENPQVFFAVLGLCNVDTGLSRQVSFSQRTADFADLKSLQQRALAP
                     GYMVSPAQRAKDMLAVIDAPDAYGIKSGIFVDMRTALADHQKAHPPLSQA"
     gene            7587..7901
                     /locus_tag="FGA82_11265"
     CDS             7587..7901
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007915028.1"
                     /locus_tag="FGA82_11265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="TMU80023.1"
                     /transl_table=11
                     /translation="MFNQVKALTESAVRQQDLLLGTPIDLSRGEDSRLYGVDGSIDSLT
                     LVSIIVDVEDKLRSQLGVEVRLADTADLPETATPFATLGTLIAYIMDRLSAAQAPVQAV
                     "
     gene            7920..9275
                     /locus_tag="FGA82_11270"
     CDS             7920..9275
                     /NRPS_PKS="Domain: AMP-binding (9-354). E-value: 2.1e-38.
                     Score: 123.8. Matches aSDomain:
                     nrpspksdomains_FGA82_11270_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     170.6; E-value: 7.5e-52)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223964.1"
                     /locus_tag="FGA82_11270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="TMU80024.1"
                     /sec_met_domain="AMP-binding (E-value: 5.7e-39, bitscore:
                     123.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVAAFLAHLKSAGSQLAVVSDEGRFTYDQLHAQVTAYSAELAAT
                     SVSDSCVLLVDNYSFNSVCMLFALWLHNNVVALSVPKGEEQLAQLAGAAGARFSVIGGT
                     PEFALVQHANSVLPPTVDGLLSRHQAGFIVFSSGSTGPAKGVVHSIAPFFERYLSAEHC
                     GAILAFLLFDHIGGLVTVLQALATHGTLILPKERSPQEVGRCIESFNVQTLHVSPTLLN
                     LATITGVFQKWNTSSLQRIYFGSEPSSPESIQRIANVMPHVQLQQLYGMSEIGVLPCRS
                     KAGDSTWMKIEDPNYSLRVVDGILHVRGATNMLGYLASAGDLASDGYLITHDLAEEHEG
                     YFRVTGRAVDLINVGGKKVFPSHVESVLMGLENVADVVVYAQPNPLLGQIVAARFTLFE
                     PESLDAFKVRLYAHVRGVLAQEQLPRVVSIAETPLYTSRFKKMRHPGALAQS"
     aSDomain        7947..8981
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGA82_11270_AMP-binding.1"
                     /evalue="2.10E-38"
                     /label="FGA82_11270_AMP-binding.1"
                     /locus_tag="FGA82_11270"
                     /protein_end="354"
                     /protein_start="9"
                     /score="123.8"
                     /tool="antismash"
                     /translation="LKSAGSQLAVVSDEGRFTYDQLHAQVTAYSAELAATSVSDSCVLL
                     VDNYSFNSVCMLFALWLHNNVVALSVPKGEEQLAQLAGAAGARFSVIGGTPEFALVQHA
                     NSVLPPTVDGLLSRHQAGFIVFSSGSTGPAKGVVHSIAPFFERYLSAEHCGAILAFLLF
                     DHIGGLVTVLQALATHGTLILPKERSPQEVGRCIESFNVQTLHVSPTLLNLATITGVFQ
                     KWNTSSLQRIYFGSEPSSPESIQRIANVMPHVQLQQLYGMSEIGVLPCRSKAGDSTWMK
                     IEDPNYSLRVVDGILHVRGATNMLGYLASAGDLASDGYLITHDLAEEHEGYFRVTGRAV
                     DLINV"
     CDS_motif       8313..8363
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGA82_11270_0001"
                     /evalue="1.10E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="FGA82_11270"
                     /protein_end="148"
                     /protein_start="131"
                     /score="15.1"
                     /tool="antismash"
                     /translation="FIVFSSGSTGPAKGVVH"
     gene            9312..9554
                     /locus_tag="FGA82_11275"
     CDS             9312..9554
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007915032.1"
                     /locus_tag="FGA82_11275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="TMU80025.1"
                     /transl_table=11
                     /translation="MVDLEKMRASIAEILLIPVAELHGETRLENSDNWDSMARIGIVAL
                     VFEQTGVNVSGEEIDGVVTVQDLFDLIDRKIEVAA"
     gene            9551..10624
                     /locus_tag="FGA82_11280"
     CDS             9551..10624
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 217.2; E-value: 4.9e-66)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007915034.1"
                     /locus_tag="FGA82_11280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="TMU80026.1"
                     /sec_met_domain="fabH (E-value: 2e-60, bitscore: 193.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLTIEGVAIRAVTAALPERRVTEEDFAELFGAKEVARIAKSTG
                     IHSIRETRTLHTSDLIIAACRNLLDQGHAAPQDIDGLIVVTQTPDSWVPGVGFMVQQAL
                     GLPQHCLVLNVAAGCSGYISALVQAGALISSGACRKILLCTGDVTTRILDERDRHVKML
                     FGDAASATLLEPGAGKFEFICGADGSGAAALQSDITYAREAGNHDCATIQRLQMDGTAV
                     MNFALSRVPQTVKALLEATGSSPAALDLLVLHQANAFMLNYLRRMIGVAAEKMPVDIDG
                     VGNTSSTSIPIVLSRHAAIGTPQAEHVVLCGFGAGLSWGALKVDLRRTTAVAPCEVPEK
                     TALADEPALAPSERLQA"
ORIGIN
        1 gtgtacttgg attccattga ttcagagcgt caacgcctgc aaccggacaa actcgcgact
       61 gctgaggctc aggcggcatt gtcgcgaatc gagcggtatg acagtcgctc gatgtactgc
      121 cgagaacatg cactgcccaa cgagcggatc tttttgagtg gtcagcaggc gctggtgagg
      181 ttgctgctgt cgcaggccga actggatcga tccaacggta ttcgcacggc ggggttcgtc
      241 agtggctacc ggggttcacc gctgggtggt gtcgaccgcg aactggtcaa ggccaaggct
      301 gtgctggaga gtgcgaacat ccgttttctg cccgcgatca atgaagatct ggcagccacg
      361 gccctgatcg gtacgcagcg cgtcgaaagt gatccgcagc gtctgtatga cggcgtattc
      421 ggcatgtggt acggcaaggg gcccggggtc gaccgctccg gtgacgcgat caagcacggc
      481 agttcctatg gctcctcacc caacggtggt gttctggtgg tcactggcga cgatcacggt
      541 tgcgtgtcgt catcgatgtc gcatcaatcc gaccgcacgc tgatcgcctg gggtttgccg
      601 gtgattcatc cggcaggcct tgatgactac gagcgctgcg gtctgtgggg gtgggcgctg
      661 tcgcgcgttt cgggattgtg ggtgggtttc aaggccatca ccgaaaccgt cgaggcaacg
      721 gcctccgttg aatcgatccc gctacccgag ttcgtcaccc ccgagatcaa tccgggaccg
      781 gacggtctgc attggcgctg gccggacctg ccgggcatgc agatcgagcg ccggaccgcg
      841 ttcaaattcg acgccgcccg cgcctttgcc ctggcgaacc cgatcgatac cgcggtcacc
      901 gcgcccgccc ggccaacgtt agtgatcggc gcggtgggca aggcgtatgg cgatgtgcgc
      961 caggccttgc agcaatgtgg catctccctc gaacaactgg aaaacgccgg cgtcgcgctg
     1021 ctcaagatca acctggtcta tccactgtcg cctgttctgg aggcctggac cctgcgcgcc
     1081 ggtaaagtac tgatcatcga agagaagcag gcgatcgtcg aagaacagct caaacagaag
     1141 tactacaacg cggcgcatga ccagcgtgcg gtgatcatcg gcaagaccga cgaacacggc
     1201 caaccgctga tctcggatca cgaagagctg cgaccgtcgc gcatcgccgc agtgctcaag
     1261 cagcgtctgc aaggtttggg cattgatctc ggtcttcccg atttctggcg cctgcccagc
     1321 gtctcgcgga tggaagactg gatccggcgc acgccttacc tgtgttccgg ttgcccgcac
     1381 aacacctcca ctcaggtgcc caagggcagt gaagcgcggc tcggtatcgg ttgccatgca
     1441 atggccgcgc gcatgcctga gcgttcgact acaggcagcg tgcagatggg tggagaaggg
     1501 gtcgactggc tgggccaggc accgttcgtg caaaccccgc acatcttcca gaacatcggc
     1561 gacgggacct tttttcactc cggtttcctc gcggtgcgtc agggcatcgc ggccggtgcg
     1621 accatcacct acaagctgct ctacaacgac gccgttgcca tgaccggtgg ccagccgatc
     1681 gacggcaagc tcacggtgaa gaaagccgtt gagctgctca aggccgaagg cgcgcagcga
     1741 atcgtggtgg tggcggacga cctgcagcgt tatcaggcac atgacagtct gccccagggc
     1801 atcgaagtat ttcaccgtga aaagctcgaa gaagtgcagt tgcaactgcg cgacacccgt
     1861 ggcgtcagcg tactgatttt cgatcaggtc tgcgccgtcg agggtcgtcg acgcaagaag
     1921 caattgccgg ccccgctggt gaagactgaa gtggtcatca acgaagcggt ctgtgaagga
     1981 tgcggcgact gccaggtcaa atccaactgc ctgtcggtga tcccggtgca aacgccgttc
     2041 ggcgccaagc gtcgcatcga tccgcactcg tgcaacaccg atctgtcgtg catcaagggc
     2101 ttctgcccaa gctttgtgac ggtgaccggc aagccgcggc aacggccgcg caaactcgcc
     2161 gacagcgccc aggtgctggc gcgggccgaa gcgctggcgc tggcgctgcc gcacgtagcg
     2221 cgttcgctcg acctgccgta tgaaatgctg ctggtgggtg ttggcggcac cggtgtggtg
     2281 accgtggcgc gggcgattgc catggccgct cacctcgacg gacgtgcggt cagcgtgctc
     2341 gactttaccg gttttgcgca aaagggcggg gccgtattga gccacatacg tctggccggt
     2401 gacgccgatg cgttgcacca gcaccgcatc gacatcggcg gtgccgacct gctgcttgct
     2461 gccgatctgg tggtggccag tgaagacgat gcgctggcaa cgctgcgacc ggacaaaacc
     2521 gtggtcatcg ccaacagtgc tctgacccag actggcgcaa tgctgcgcaa tacccgattg
     2581 ggtatagaaa ccgacgcgat tcaaacgttt ctgaagcaaa aggtcggcgc cgaacacttc
     2641 cacagcctgg atgccggtga gttggcgacc agcctggtca gcccgatgca agccaacatg
     2701 ctgttgctcg gttacgcgtg gcagaagggc acgataccgg tgtcgttgcc ggcgctgaaa
     2761 aaagccattg atctggccgg cagcgccgcg accaaccatt tggctttcgc ctggggccgg
     2821 ttgtgggcgc aggattcggc ttttgtcgcg ccttacctgg agcaacccgt ggatgccgtg
     2881 tcgacaattg cgatccgcga catcagcgac atgcgcggcc gccgcgaaag cctcgaacaa
     2941 atggtcgacc atcgcagcga gttcctcagc ggctaccaga atgcagcgta tgcggcgcgt
     3001 taccgcaagg tcatcgagca actgcgagcg ctgccggcgg ccggtgatga cagcgcgctg
     3061 acccaggcag tgacacgcaa cctcttcaag ctgatggctt acaaggacga gtacgaagtt
     3121 gcacggctgc tcaccacgcg cagtttcact gactcgctga aggcccgctt cgacggtggc
     3181 attcgtctga aattccactt tgccttgccg ctgctgcgca agaaccaggc gagcaccggc
     3241 gagccgaaaa agatcgcgct ttccggctgg atcctgccgc tgctgaaggt cctggccaag
     3301 ggccgggtgt tgcgcaacac ccggttcgat ccgctgggct tctctgccga gcgccgcgaa
     3361 gagcgtcgct tgctcaatga ctacgagcaa accctgcaac gcctgttgcc gaaattgaac
     3421 tcggagaatc tgtcggcgtt cgtcgcctgg gcaaatctgc cggattcgat tcgcggctac
     3481 ggtcacgtca aggagcgctc gatcgcggcg gcgcgtctgc gcgagaaaga actcatcgaa
     3541 cagattctgg cggacaagcc ggtcattcac ggtgtcgagt catggcagcc atccaccgtc
     3601 atcgccaggc aactgagcga ggaagagcgc gacgtgatgg aagcctcttg accgaaggct
     3661 acgccagccc cgcagaacaa caaatacaac aactacccag atgagctgat aacgatgaat
     3721 aacgacagca ttgcgcccga cctcctgcac aaaggttcgg ctgacgacgt tttgattggc
     3781 gcccccagag acgcgctgcc gctgtatgtg aacgaaacac tgatcgaggc caacgggcat
     3841 aacccgttgg taggcaatta cgctgcaggc gccaaccagc cacgccgctt cgagattacg
     3901 cccgagctgc agaaaaacag ccgaatgggt ggcgatgatg aatggaatcg gctgagggcg
     3961 ctgccgtacc agatcgtcgc cgcacagctg gaggccgctg gaatccgcag cgatagcctg
     4021 gaagccgccg tggccgcgct gtgcgaatcg attccggcga tccgccgcgc cagttcgttc
     4081 cgcttcatca ataacgccga caattatttc ttctatcgca aggcgcacga acatgtgccg
     4141 gggacgatgt tcatcgaggc ggcgcggcaa gcggtttatc accacctgta tcaccacacc
     4201 gaccatgcgc gcggcgccgt caccgtcagc gtcaatgagc tgaacgcgag ttttttcgct
     4261 tacgcagaac tgatgtatcc gatcgaactg gtggtcgaca acatgacccc gagcgatgcc
     4321 acgtcgccga agaaaatcca tctgcgcgtt gcgttctatc aacgtcagac cctgttcgcc
     4381 accgtcgaca ccaaagccac cgtgatcgac atgccgctgt tcgaaaagac ccgcaatatc
     4441 ttcatctact gcaacgactg gtttgcaccg ctgcaaccgt tgaagctggc ctgcacgatc
     4501 agcgacgcgc aggggcgcaa agttgaagtg cagctattgg gcctgggcaa gagcggttgc
     4561 gtgacgacaa cggcggatat gtccgagccg gtcactctgc aaatcgtcta tgaaggcaaa
     4621 ttgagtttta ccgccggcat ccgccccgtc gggcagggca agcattcttc gtgggaattc
     4681 gccgaggtag atttcaacgg cttgcaagtg atcagcgaca tgatcaagcg cggctttgtc
     4741 cacctcgatg agccggccct tgcggccttg cagcaatgat cgtggcaacc cccactttcc
     4801 aggcggccac ccgaacgctg catttcggcg cgcaggcagt ggcgaagaat cgattgtatt
     4861 tttcctcgct cggcatggat ctgtgtgacg aacacggctt cccgcaaccg gcgtttttct
     4921 cggtctatca agctttgatg gacggcggcg cagggtttgg ttttctcggc aatgccagcg
     4981 tcgacgccga tgcacgttac aacagccgtg gtctgcgcct gacctcagcg gcccacgcgc
     5041 aggccctgcg gccgctgttt gaagcggcgc gggcgcgtgg tttcccgttg ggcgtgcaac
     5101 tgcagcatta cgggccgcag tcattgccgt cgaagcaggg aatcattctg acccccagcg
     5161 ccatcgcgtc gccgaccatc ctcagcgcgt accccgaggc acgggcggtg gcgatgagcg
     5221 aggcacagat ccagcgctgc atcgagcagt tctgtgtcgc cgcccgctat gcgcaacagg
     5281 ccggcgccac gttgatccag ctacaggcgt ccaacggtta tttgatcagc agcttccttt
     5341 cgccaaagac caatcggcgc gtggatgact ggggcggcac gccgctcaag cgcgccaggc
     5401 tgttgctttc gattgtcgac gggatccgcc aggccaccga tcacaaggtc gcggtcactg
     5461 tgcgcctggg catggatgac ggcctcggtg cagagggcca gcacgccgcg ctgttgggtg
     5521 atgtcgtcgc cgcgctggag gccagtgggg tcgcagcgat tacctgttcg ctgggcatca
     5581 gcgagacctt tcgtttcttt ttcaaaaatg ccgggcaagc cctggccatg tcgcgggaag
     5641 gctgccgcta tctgaagcgt ttcgtgcgga ttccgctggg ctttaccggt tcggtcgcgg
     5701 acgtggcgca agcagatgaa atcatcgcca gtggcgatgc cgatttcgtc gggttcggcc
     5761 gcgccatgct cgccgacaac gacttcgtcg ccaagcaact ggcggggcga gccgatcagc
     5821 tcaaccgctg ccgaggcgat gcgttttgtt tccgcgacaa aaaagagccc atggccgagc
     5881 gcgtgtattg ctgcgtcaat cctgcctacc gccggccaga acaactccaa cagtactacg
     5941 aggaaaacct gaaatgaact tcaccgccaa gatcgctctc gttgtcgggg gcacacgtgg
     6001 gatcggcttt gatgtcagcc agaagctgat cgaagccggc tgcatctgtt acatcaccgg
     6061 ccgcaacgaa gatgatggcc tgaccgcgca aagtcgtctc ggcgaaaact gcacgttcat
     6121 ccgcagcgac gtcaccgacg aatcctcggt gatcgagctg ttccgcctca tcaacgacaa
     6181 gcacggtcga ctcgatctgg ctgtcaacaa tgctggcgtc acctcaaaac acgcgccgat
     6241 ccgcgacatg gatttcgctg actggaagcg cgtactggag atcaatctgc tgggcccgct
     6301 gctgttgctc aagcacgaaa ccaacctgat ctccaaacac gccggcggtt cgatcgtcaa
     6361 cgtctcgtcc tgcgccggtt tgctgggggt tgccaaacaa agcgcctatt ccaccagcaa
     6421 ggctgcgctg aacatgctga ctcaggtctg cgcgattgaa tgcgctgaag aagccctgcc
     6481 tgagcggcat tcgattcgcg tcaacgccgt atgccccggg ccgacattgg gtggcatgaa
     6541 ctcggaagaa cgcctgaaag ccaacccgga gtccacccgg cacaagctgc aagtgacggc
     6601 gatgaagcgc ttcgccaacc caggcgagat ttccgccgcc attctctggc tgctgagtga
     6661 cgcgtcttcg tttgtcaccg gcaccgtgat gccggtcgat ggcggctttt cggccggtaa
     6721 attctgatgc acaccgtaaa gcgtaacccc actgcaggtg ctcgcgaaaa ggccagccac
     6781 cgggtgttta tcacgggcgt gagcagcggc atcggcgagg cgctggcgct gcttcatttg
     6841 caaaacgggc atacggtttt cggcacttcg cgtcgtcagc cctatggcct gatggactat
     6901 ccggacttcc attttcggcc gttcgatctg tcccggccga gcgcgatgga cgagctgttc
     6961 gaggacaact ttgccagcgt tctggaacag ggcgtcgaca gggttttcct gaatgccggg
     7021 gtcagcggca acgtaccagg gcgtgctgcg gaattctcgc tggatgagct gcagcatgtg
     7081 ctcaacgtca acgtgctggc caataaagcc atgcttgacc tcgtgctgtc gtcttcccgg
     7141 cgcccgacga catgcgtgct gtcagcctcg atggcgggcg tacgctttcg cgcgggcacg
     7201 ctgccataca gcctgtcgaa agccgcgctg gcggcattgg gcggtgttta cgccgaggaa
     7261 aatccgcagg tcttcttcgc ggtgctcggt ctgtgcaacg tcgataccgg tctgtcccgg
     7321 caggtgagct tcagtcagcg cactgccgac ttcgccgacc tcaagtcgct gcagcaacga
     7381 gccctggcgc ccggttacat ggtgtcgccc gcacaacgcg cgaaggacat gctggcggtg
     7441 attgacgcgc ccgatgccta cggcatcaag agcgggatat tcgtcgacat gcgcacagcg
     7501 ctggccgatc accagaaagc gcacccgcca ttgtctcaag cgtagtgaac gcagggacct
     7561 gcatcagcca ataaaggaat gttggaatgt tcaatcaagt caaagcgctg accgagtcag
     7621 ccgttcggca acaggatctg ttgctgggta ccccgatcga tttgtcccgt ggcgaagaca
     7681 gccgccttta cggcgtggac ggcagcatcg attccctgac cctggtctcg atcattgtcg
     7741 atgtcgagga caaactgcgc agccagctgg gcgttgaggt gcgtctggcc gataccgccg
     7801 acctgcccga aaccgccacg ccgtttgcca cgctgggcac gctgatcgcc tacatcatgg
     7861 accggttgtc tgcggcgcaa gcgcccgttc aggccgtttg accgaacgag gggttgggta
     7921 tgcaagtagc agcatttttg gctcatctga aaagcgccgg cagccaactg gcagtcgtca
     7981 gcgatgaggg ccgctttacc tatgaccagt tgcacgcaca agtaaccgcg tacagcgcgg
     8041 agctggcggc aacatccgtc agcgattcct gcgtgctgtt ggtcgacaac tacagcttca
     8101 acagcgtctg catgctgttc gcgttgtggc tgcacaacaa cgtggtggcg ttgtctgtgc
     8161 ccaagggcga ggaacagctc gcgcagttgg cgggcgcggc gggcgcgagg ttttccgtca
     8221 ttggcgggac gccggagttt gcgcttgtcc agcacgccaa ctctgtcttg ccaccgaccg
     8281 tagacggact gctgtcgcgg caccaggccg gcttcattgt gttttcttca ggctcgacag
     8341 gtcctgccaa aggcgtggtg cacagcattg cgccgttctt cgagcgctac ctgagtgccg
     8401 aacactgcgg cgcgattctg gcgtttctgc tgttcgatca catcggtggg ctggtcacgg
     8461 ttctgcaggc gctggcgacc catggcacgc tgatcctgcc caaggagcgc tcgccgcaag
     8521 aggtcgggcg ctgtatcgaa tcgttcaacg tgcaaaccct gcacgtctcg ccgacgctac
     8581 tgaacctggc aacgatcact ggcgtcttcc agaagtggaa cacgagcagt ctgcagcgca
     8641 tctatttcgg ctccgaaccg agttcgccgg aatccatcca gcgcattgcc aacgtcatgc
     8701 cgcacgtgca attgcagcag ttgtacggga tgtcggaaat cggcgtgctg ccgtgccgca
     8761 gcaaggccgg cgacagcacg tggatgaaga tcgaagaccc gaactacagc ctgcgggtgg
     8821 tcgacggtat tttgcacgtg cgcggcgcaa ccaacatgct tggctacctg gccagcgctg
     8881 gtgacctggc gagcgacggc tacctgatca ctcatgatct ggccgaggag cacgagggct
     8941 atttccgggt cacggggcgg gcggtcgatc tgatcaatgt cggtggcaaa aaggtctttc
     9001 cgtcgcacgt ggaaagtgtg ctgatgggcc tggaaaacgt cgcggatgtg gtcgtttacg
     9061 cgcagcccaa cccactgctc gggcaaatcg tcgccgcgcg tttcacgctg ttcgagccgg
     9121 aaagcctgga cgcgttcaag gtccgcttgt atgcacacgt tcgcggcgta ttggcgcagg
     9181 aacaactgcc gcgggtggtc tccatcgccg agactccgct gtacaccagc cgcttcaaga
     9241 aaatgcgtca ccccggcgct ctcgcccagt cgtgagaccg ctttactcat cacgttataa
     9301 ggaaatgaca aatggttgat ctggaaaaaa tgcgcgcaag catcgctgaa atcctgctca
     9361 tcccggtggc cgaactgcac ggtgagacgc ggctggaaaa cagcgataac tgggactcga
     9421 tggcgcgaat cgggattgtc gccctggtgt tcgaacaaac cggtgtgaac gtgtcgggcg
     9481 aggagatcga cggtgtggtc acggtgcagg atctgttcga tctgatcgac cggaaaatcg
     9541 aggtcgccgc atgagtctgc tgaccattga gggcgtcgca attcgggcgg tcacggcggc
     9601 gctgcccgag cgtcgggtga ctgaagagga ctttgccgaa ctgttcggcg ccaaggaagt
     9661 tgcgcgtatt gccaagagca ccggcatcca ttcgatccgc gaaaccagaa ccctgcacac
     9721 ctccgatctg atcatcgccg cgtgccgcaa cctgctcgat caagggcatg cggcaccaca
     9781 ggacatcgat ggcctgatcg tggtgaccca gacgcccgac tcgtgggtgc cgggcgtcgg
     9841 cttcatggtg cagcaggccc tcggcctgcc gcagcattgc ctggtactga atgtggctgc
     9901 aggttgctcc ggctatatct ctgcgctggt tcaggcgggc gcgctgattt catccggggc
     9961 ctgcaggaaa atcctgctgt gcaccgggga cgtgaccacg cgaatcctcg atgaacgcga
    10021 ccgccatgtg aaaatgctct ttggtgacgc tgcgtcggca acgttgctgg agccgggtgc
    10081 aggcaagttc gagttcatct gcggcgccga tggcagcggc gccgcggcgc tgcagtccga
    10141 catcacctac gcgcgggagg cgggcaacca cgattgcgcg accatccagc gtttgcagat
    10201 ggatggcacg gcggtgatga attttgccct gagccgggtc ccgcagaccg tcaaggcttt
    10261 gcttgaggcc acgggatcaa gtcctgctgc gctggacttg ctggtactgc accaggcgaa
    10321 cgcgttcatg ctcaattacc tgcgacggat gattggcgtg gcggcggaaa agatgccggt
    10381 cgacatcgat ggcgtcggca acaccagctc cacctcgatt ccgatcgtgt tgtcgcgtca
    10441 tgccgcgatc ggcacgccgc aggccgagca cgttgtgttg tgcggtttcg gcgccgggct
    10501 gtcgtggggc gctttgaagg tcgatctgcg tcgcacgacc gctgtggcac cttgcgaagt
    10561 gccggagaaa accgctctgg cggacgaacc ggctctggct ccgagtgagc gtttgcaggc
    10621 ctga
//
