BGC0002072 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002072 (Streptomyces sp. Mg1)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS	1	191,285	High	linearmycin A/linearmycin B/linearmycin C/linearmycin C	PKS:Type I

BGC0002072 - Region 1 - T1PKS

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Location: 1 - 191,285 nt. (total: 191,285 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 191,286
Label		BGC0002072

Tailoring functions

Oxidoreductases: dehydrogenase

M444_04810: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: PPTase acylase transferase

M444_04755: acetyl-CoA carboxylase, carboxyl transferase,

smcogs: SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,

M444_04770: 4'-phosphopantetheinyl transferase

smcogs: SMCOG1060: 4'-phosphopantetheinyl transferase

M444_04790: glucose-1-phosphate adenylyl/thymidylyltransferase

smcogs: SMCOG1064: glucose-1-phosphate adenylyl/thymidylyltransferase

M444_04805: malonyl CoA-acyl carrier protein transacylase

smcogs: SMCOG1021: malonyl CoA-acyl carrier protein transacylase

M444_04820: malonyl CoA-acyl carrier protein transacylase

smcogs: SMCOG1021: malonyl CoA-acyl carrier protein transacylase

Hydrolases: esterase

M444_04785: thioesterase

smcogs: SMCOG1004: thioesterase

M444_04885: thioesterase

smcogs: SMCOG1004: thioesterase

Ligases: ligase synthase

M444_04780: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

M444_04815: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

M444_04825: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

M444_04830: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

M444_04835: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

M444_04840: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

M444_04845: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

M444_04850: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002072.3	1.00	PKS	linearmycin A, linearmycin B, linearmycin C, linearmycin C	Streptomyces sp. Mg1
BGC0002355.2	0.81	PKS, other (other)	tetrafibricin	Streptomyces neyagawaensis
BGC0001276.3	0.76	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.3	0.75	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001273.3	0.75	PKS	asperlactone	Aspergillus ochraceus
BGC0001244.3	0.75	PKS	(-)-Mellein	Parastagonospora nodorum
BGC0002357.3	0.71	PKS, other (other)	neomediomycin B	Streptomyces sp. RK95-74
BGC0000052.5	0.70	PKS	ECO-02301	Streptomyces aizunensis
BGC0002356.3	0.68	PKS, other (other)	mediomycin A	Streptomyces blastmyceticus
BGC0001662.4	0.68	PKS	mediomycin A	Kitasatospora mediocidica

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002072.3	1.00	PKS	linearmycin A, linearmycin B, linearmycin C, linearmycin C	Streptomyces sp. Mg1
BGC0002355.2	0.81	PKS, other (other)	tetrafibricin	Streptomyces neyagawaensis
BGC0001276.3	0.76	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.3	0.75	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001273.3	0.75	PKS	asperlactone	Aspergillus ochraceus
BGC0001244.3	0.75	PKS	(-)-Mellein	Parastagonospora nodorum
BGC0002357.3	0.71	PKS, other (other)	neomediomycin B	Streptomyces sp. RK95-74
BGC0000052.5	0.70	PKS	ECO-02301	Streptomyces aizunensis
BGC0002356.3	0.68	PKS, other (other)	mediomycin A	Streptomyces blastmyceticus
BGC0001662.4	0.68	PKS	mediomycin A	Kitasatospora mediocidica

Similar known clusters from MIBiG 4.0

Module view

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Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 191285:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ohmal - ohmal - ccmal - ohmal - ccmal - ohmal - ohmal) + (ccmal - ohmal) + (ccmal - ohmal - ohmal - ccmal) + (Me-ohmal) + (ohmal - ccmal - ccmal) + (ccmal - ccmal - ccmal) + (Me-ohmal - Me-ohmal) + (ccmal - redmal - ccmal - ccmal) + (ccmal - ccmal - Me-ccmal)
Non-colinear ordering:: M444_04850 + M444_04845 + M444_04840 + M444_04835 + M444_04830 + M444_04825 + M444_04820 + M444_04815 + M444_04810

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

M444_04780: X

AMP-binding (15..371): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: QYSDCGSNIK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

M444_04805: pk

PKS_AT (24..297): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

M444_04810: mal - mal - mmal

PKS_AT (584..874): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 235.1
inactive: 104.3
Methoxymalonyl-CoA: 63.1
Methylmalonyl-CoA: 56.9
Propionyl-CoA: 37.0
Benzoyl-CoA: 24.7
Ethylmalonyl-CoA: 20.7
Acetyl-CoA: 19.5
Isobutyryl-CoA: 17.7
trans-1,2-CPDA: 14.9
CHC-CoA: 12.6
fatty_acid: 11.8
2-Methylbutyryl-CoA: 10.9
3-Methylbutyryl-CoA: 0.0

PKS_AT (2316..2602): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 224.8
inactive: 105.8
Methoxymalonyl-CoA: 62.6
Methylmalonyl-CoA: 52.6
Propionyl-CoA: 31.9
Benzoyl-CoA: 22.4
Isobutyryl-CoA: 21.8
CHC-CoA: 19.3
Ethylmalonyl-CoA: 17.7
Acetyl-CoA: 16.8
fatty_acid: 11.6
2-Methylbutyryl-CoA: 8.6
trans-1,2-CPDA: 4.4
3-Methylbutyryl-CoA: 0.0

PKS_AT (4038..4337): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 223.4
Ethylmalonyl-CoA: 215.7
Methoxymalonyl-CoA: 181.4
2-Methylbutyryl-CoA: 148.9
trans-1,2-CPDA: 133.6
Propionyl-CoA: 116.9
Malonyl-CoA: 113.4
CHC-CoA: 110.4
Isobutyryl-CoA: 98.0
Benzoyl-CoA: 74.9
Acetyl-CoA: 59.8
3-Methylbutyryl-CoA: 58.1
fatty_acid: 45.4
inactive: 39.5

M444_04815: mal - mal - mal - mal

PKS_AT (591..889): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 87.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 223.4
inactive: 113.0
Methoxymalonyl-CoA: 72.4
Methylmalonyl-CoA: 62.8
Propionyl-CoA: 42.1
Ethylmalonyl-CoA: 33.2
Isobutyryl-CoA: 30.1
Acetyl-CoA: 28.3
Benzoyl-CoA: 24.7
trans-1,2-CPDA: 16.9
fatty_acid: 16.0
CHC-CoA: 15.6
2-Methylbutyryl-CoA: 14.4
3-Methylbutyryl-CoA: 0.0

PKS_AT (2396..2695): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 79.2%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 211.1
inactive: 107.8
Methoxymalonyl-CoA: 57.1
Methylmalonyl-CoA: 47.0
Isobutyryl-CoA: 31.3
Propionyl-CoA: 23.8
Acetyl-CoA: 22.6
Benzoyl-CoA: 20.2
Ethylmalonyl-CoA: 16.9
CHC-CoA: 9.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

PKS_AT (4484..4769): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 239.3
inactive: 115.3
Methoxymalonyl-CoA: 65.1
Methylmalonyl-CoA: 60.2
Propionyl-CoA: 42.4
Benzoyl-CoA: 26.9
Ethylmalonyl-CoA: 24.2
Isobutyryl-CoA: 20.7
trans-1,2-CPDA: 16.8
CHC-CoA: 16.6
Acetyl-CoA: 15.9
2-Methylbutyryl-CoA: 15.7
fatty_acid: 10.6
3-Methylbutyryl-CoA: 0.0

PKS_AT (6210..6495): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 239.6
inactive: 116.7
Methoxymalonyl-CoA: 66.9
Methylmalonyl-CoA: 57.7
Propionyl-CoA: 38.4
Benzoyl-CoA: 25.6
Ethylmalonyl-CoA: 25.4
Isobutyryl-CoA: 18.8
Acetyl-CoA: 18.0
CHC-CoA: 17.2
trans-1,2-CPDA: 14.1
2-Methylbutyryl-CoA: 12.0
fatty_acid: 9.7
3-Methylbutyryl-CoA: 0.0

M444_04820: mmal - mmal

PKS_AT (560..859): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 226.2
Ethylmalonyl-CoA: 218.3
Methoxymalonyl-CoA: 183.1
2-Methylbutyryl-CoA: 159.3
trans-1,2-CPDA: 131.2
Propionyl-CoA: 118.3
Malonyl-CoA: 114.8
CHC-CoA: 108.2
Isobutyryl-CoA: 104.5
Benzoyl-CoA: 79.3
3-Methylbutyryl-CoA: 63.9
Acetyl-CoA: 62.5
inactive: 40.7
fatty_acid: 37.1

PKS_AT (2124..2423): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 226.5
Ethylmalonyl-CoA: 219.6
Methoxymalonyl-CoA: 183.3
2-Methylbutyryl-CoA: 159.7
trans-1,2-CPDA: 126.7
Propionyl-CoA: 115.9
Malonyl-CoA: 115.7
CHC-CoA: 109.8
Isobutyryl-CoA: 106.5
Benzoyl-CoA: 77.6
3-Methylbutyryl-CoA: 62.7
Acetyl-CoA: 61.2
inactive: 40.9
fatty_acid: 37.1

M444_04825: mal - mal - mal

PKS_AT (573..861): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 235.4
inactive: 107.7
Methoxymalonyl-CoA: 59.8
Methylmalonyl-CoA: 55.1
Propionyl-CoA: 33.8
Isobutyryl-CoA: 23.8
Benzoyl-CoA: 19.3
Ethylmalonyl-CoA: 18.2
Acetyl-CoA: 15.5
CHC-CoA: 13.8
fatty_acid: 13.0
2-Methylbutyryl-CoA: 11.3
trans-1,2-CPDA: 7.8
3-Methylbutyryl-CoA: 0.0

PKS_AT (2336..2621): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 234.3
inactive: 106.0
Methoxymalonyl-CoA: 63.8
Methylmalonyl-CoA: 56.7
Propionyl-CoA: 37.4
Benzoyl-CoA: 26.7
Ethylmalonyl-CoA: 23.4
Isobutyryl-CoA: 17.9
Acetyl-CoA: 17.0
CHC-CoA: 13.7
trans-1,2-CPDA: 13.1
fatty_acid: 10.8
2-Methylbutyryl-CoA: 6.4
3-Methylbutyryl-CoA: 0.0

PKS_AT (4084..4369): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 231.8
inactive: 115.3
Methoxymalonyl-CoA: 72.9
Methylmalonyl-CoA: 60.7
Propionyl-CoA: 38.1
Benzoyl-CoA: 31.7
Ethylmalonyl-CoA: 21.2
Isobutyryl-CoA: 21.1
CHC-CoA: 19.4
Acetyl-CoA: 17.4
trans-1,2-CPDA: 13.8
2-Methylbutyryl-CoA: 13.4
fatty_acid: 12.1
3-Methylbutyryl-CoA: 0.0

M444_04830: mal - mal - mal

PKS_AT (573..861): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 232.1
inactive: 106.6
Methoxymalonyl-CoA: 62.6
Methylmalonyl-CoA: 56.2
Propionyl-CoA: 34.9
Benzoyl-CoA: 24.0
Ethylmalonyl-CoA: 23.0
CHC-CoA: 19.9
Isobutyryl-CoA: 18.9
Acetyl-CoA: 17.0
fatty_acid: 12.7
2-Methylbutyryl-CoA: 12.3
trans-1,2-CPDA: 10.7
3-Methylbutyryl-CoA: 0.0

PKS_AT (2130..2414): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 238.1
inactive: 109.2
Methoxymalonyl-CoA: 70.2
Methylmalonyl-CoA: 62.3
Propionyl-CoA: 43.3
Ethylmalonyl-CoA: 25.2
Benzoyl-CoA: 24.5
Isobutyryl-CoA: 21.9
CHC-CoA: 20.6
Acetyl-CoA: 17.6
fatty_acid: 15.2
2-Methylbutyryl-CoA: 11.9
trans-1,2-CPDA: 11.7
3-Methylbutyryl-CoA: 0.0

PKS_AT (3906..4197): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 213.3
inactive: 99.8
Methoxymalonyl-CoA: 58.9
Methylmalonyl-CoA: 43.7
Propionyl-CoA: 32.7
Isobutyryl-CoA: 19.0
Acetyl-CoA: 18.3
Ethylmalonyl-CoA: 17.6
Benzoyl-CoA: 15.2
CHC-CoA: 11.9
trans-1,2-CPDA: 8.8
2-Methylbutyryl-CoA: 8.7
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

M444_04835: mmal

PKS_AT (560..859): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 224.5
Ethylmalonyl-CoA: 213.9
Methoxymalonyl-CoA: 180.4
2-Methylbutyryl-CoA: 158.4
trans-1,2-CPDA: 127.8
Propionyl-CoA: 117.2
Malonyl-CoA: 113.4
CHC-CoA: 106.6
Isobutyryl-CoA: 97.5
Benzoyl-CoA: 76.6
3-Methylbutyryl-CoA: 66.5
Acetyl-CoA: 66.4
fatty_acid: 41.2
inactive: 40.9

M444_04840: mal - mal - mal - mal

PKS_AT (571..856): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 242.5
inactive: 111.6
Methoxymalonyl-CoA: 70.3
Methylmalonyl-CoA: 63.1
Propionyl-CoA: 43.8
Benzoyl-CoA: 25.9
Ethylmalonyl-CoA: 23.9
Isobutyryl-CoA: 21.5
CHC-CoA: 18.5
fatty_acid: 15.2
Acetyl-CoA: 14.9
trans-1,2-CPDA: 14.0
2-Methylbutyryl-CoA: 12.9
3-Methylbutyryl-CoA: 0.0

PKS_AT (2392..2679): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 234.0
inactive: 101.5
Methoxymalonyl-CoA: 61.0
Methylmalonyl-CoA: 52.3
Propionyl-CoA: 37.2
Benzoyl-CoA: 23.6
Ethylmalonyl-CoA: 17.5
Acetyl-CoA: 16.4
CHC-CoA: 14.6
Isobutyryl-CoA: 14.2
trans-1,2-CPDA: 13.5
2-Methylbutyryl-CoA: 9.8
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (3901..4187): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 238.9
inactive: 110.8
Methoxymalonyl-CoA: 68.7
Methylmalonyl-CoA: 60.6
Propionyl-CoA: 45.3
Benzoyl-CoA: 23.1
Isobutyryl-CoA: 22.9
Ethylmalonyl-CoA: 21.7
Acetyl-CoA: 20.5
2-Methylbutyryl-CoA: 17.3
CHC-CoA: 16.7
fatty_acid: 9.6
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (5357..5644): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 233.7
inactive: 102.8
Methoxymalonyl-CoA: 61.7
Methylmalonyl-CoA: 53.6
Propionyl-CoA: 38.7
Benzoyl-CoA: 22.1
Acetyl-CoA: 18.5
Ethylmalonyl-CoA: 17.2
Isobutyryl-CoA: 15.0
CHC-CoA: 13.6
2-Methylbutyryl-CoA: 12.3
trans-1,2-CPDA: 10.2
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

M444_04845: mal - mal

PKS_AT (564..847): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 237.3
inactive: 118.5
Methoxymalonyl-CoA: 70.5
Methylmalonyl-CoA: 60.7
Propionyl-CoA: 39.5
Benzoyl-CoA: 25.3
Ethylmalonyl-CoA: 22.0
Isobutyryl-CoA: 18.8
CHC-CoA: 18.5
fatty_acid: 17.3
Acetyl-CoA: 17.2
2-Methylbutyryl-CoA: 14.8
trans-1,2-CPDA: 13.7
3-Methylbutyryl-CoA: 0.0

PKS_AT (2340..2624): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 232.6
inactive: 109.9
Methoxymalonyl-CoA: 67.7
Methylmalonyl-CoA: 54.6
Propionyl-CoA: 36.3
Benzoyl-CoA: 24.1
CHC-CoA: 19.2
Isobutyryl-CoA: 19.0
Acetyl-CoA: 16.1
Ethylmalonyl-CoA: 13.5
fatty_acid: 12.2
trans-1,2-CPDA: 10.3
2-Methylbutyryl-CoA: 7.5
3-Methylbutyryl-CoA: 0.0

M444_04850: mal - mal - mal - mal - mal - mal - mal

PKS_AT (726..1020): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 91.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 233.4
inactive: 136.7
Methoxymalonyl-CoA: 60.9
Methylmalonyl-CoA: 55.6
Propionyl-CoA: 33.0
Benzoyl-CoA: 22.9
Isobutyryl-CoA: 20.0
Acetyl-CoA: 18.5
trans-1,2-CPDA: 13.5
2-Methylbutyryl-CoA: 10.6
Ethylmalonyl-CoA: 10.1
CHC-CoA: 8.6
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (2262..2551): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 228.4
inactive: 107.2
Methoxymalonyl-CoA: 61.4
Methylmalonyl-CoA: 54.2
Propionyl-CoA: 38.4
Ethylmalonyl-CoA: 24.0
Benzoyl-CoA: 23.2
Isobutyryl-CoA: 18.3
2-Methylbutyryl-CoA: 16.2
CHC-CoA: 16.0
Acetyl-CoA: 14.5
trans-1,2-CPDA: 11.6
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (3792..4081): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 229.6
inactive: 108.2
Methoxymalonyl-CoA: 57.9
Methylmalonyl-CoA: 51.1
Propionyl-CoA: 33.3
Benzoyl-CoA: 23.6
Acetyl-CoA: 17.1
Isobutyryl-CoA: 16.6
CHC-CoA: 11.6
Ethylmalonyl-CoA: 11.4
trans-1,2-CPDA: 10.9
2-Methylbutyryl-CoA: 10.8
fatty_acid: 9.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (5574..5861): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 234.7
inactive: 105.4
Methoxymalonyl-CoA: 64.4
Methylmalonyl-CoA: 54.9
Propionyl-CoA: 37.4
Benzoyl-CoA: 23.2
Isobutyryl-CoA: 17.4
Ethylmalonyl-CoA: 16.5
CHC-CoA: 15.5
Acetyl-CoA: 14.0
2-Methylbutyryl-CoA: 13.9
trans-1,2-CPDA: 13.0
fatty_acid: 11.4
3-Methylbutyryl-CoA: 0.0

PKS_AT (7081..7371): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 230.4
inactive: 109.6
Methoxymalonyl-CoA: 62.2
Methylmalonyl-CoA: 57.4
Propionyl-CoA: 36.3
Benzoyl-CoA: 24.8
Ethylmalonyl-CoA: 18.1
Isobutyryl-CoA: 17.8
Acetyl-CoA: 15.8
CHC-CoA: 15.7
2-Methylbutyryl-CoA: 12.5
trans-1,2-CPDA: 12.2
fatty_acid: 10.8
3-Methylbutyryl-CoA: 0.0

PKS_AT (8863..9148): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 239.1
inactive: 105.3
Methoxymalonyl-CoA: 59.8
Methylmalonyl-CoA: 49.3
Propionyl-CoA: 36.8
Benzoyl-CoA: 21.8
Acetyl-CoA: 17.1
Isobutyryl-CoA: 15.1
Ethylmalonyl-CoA: 14.6
trans-1,2-CPDA: 13.7
CHC-CoA: 11.0
2-Methylbutyryl-CoA: 7.2
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (10374..10661): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 234.9
inactive: 108.6
Methoxymalonyl-CoA: 61.4
Methylmalonyl-CoA: 50.2
Propionyl-CoA: 33.5
Benzoyl-CoA: 24.5
Acetyl-CoA: 20.5
Isobutyryl-CoA: 16.1
Ethylmalonyl-CoA: 15.2
trans-1,2-CPDA: 9.9
fatty_acid: 9.8
CHC-CoA: 9.6
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

Link to PARAS substrate predictor