BGC0002081: streptoketide A biosynthetic gene cluster from Streptomyces sp. Tue6314
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Location: 5,927 - 26,330 nt. (total: 20,404 nt).
This entry is originally from NCBI GenBank MK424349.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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Gene details
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General
Compounds
Genes
Polyketide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002081
Short description streptoketide A biosynthetic gene cluster from Streptomyces sp. Tue6314
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Other)
Loci NCBI GenBank: MK424349.1
Compounds
  • streptoketide A
  • streptoketide B
  • streptoketide C
  • S2502
  • S2507
  • UWM5
Species Streptomyces sp. Tue6314 [taxonomy]
References
Chemical products information
streptoketide A
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Chemical database entries
NPAtlas
streptoketide B
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Chemical database entries
NPAtlas
streptoketide C
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S2502
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S2507
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UWM5
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List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QED90611.1
 5928 - 6173 (-) acyl carrier protein
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  • QED90612.1
 6212 - 7480 (-) ketosynthase chain-length factor
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  • QED90637.1
 7477 - 8748 (-) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
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  • QED90613.1
 9095 - 9598 (+) MarR family transcriptional regulator
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  • QED90614.1
 9682 - 10137 (+) putative cyclase
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  • QED90615.1
 10197 - 11003 (-) SARP family transcriptional regulator
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  • QED90616.1
 11283 - 12839 (-) cholesterol oxidase
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  • QED90617.1
 12979 - 13653 (-) SAM-dependent methyltransferase
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  • QED90618.1
 13900 - 14703 (+) ketoacyl reductase
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  • QED90619.1
 14736 - 15779 (+) putative cyclase
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  • QED90620.1
 15772 - 17619 (+) AMP-dependent ligase
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  • QED90621.1
 17609 - 18349 (+) short-chain dehydrogenase/reductase SDR
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  • QED90622.1
 18373 - 19164 (+) short-chain dehydrogenase
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  • QED90623.1
 19175 - 20428 (+) FAD-binding monooxygenase
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  • QED90624.1
 20425 - 21198 (+) putative cyclase
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  • QED90625.1
 21371 - 22357 (+) aldo/keto reductase
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  • QED90626.1
 22443 - 23474 (-) 3-oxoacyl-ACP synthase III
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  • QED90627.1
 23649 - 24650 (+) acyltransferase domain-containing protein
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  • QED90628.1
 24720 - 26330 (+) methylmalonyl-CoA carboxyltransferase
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Polyketide-specific information
Subclass Other
Cyclic? yes
Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: ZA5Z4HT5MOJPYYEQY2X7STLX, no GDPR consent given).
  • Hidden contributor (ID: 3UOU7PODQJXIM6BEPUHHRRA5, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
  • Remove negative ketide_length
  • Added version to NCBI accession
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
  • Changed chemical structures for compounds: streptoketide A, streptoketide B.
Detailed domain annotation
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