LOCUS       BGC0002089             18465 bp    DNA     linear   BCT 27-FEB-2015
DEFINITION  Streptomyces scabiei 87.22 complete genome.
ACCESSION   BGC0002089
VERSION     BGC0002089
KEYWORDS    .
SOURCE      Streptomyces scabiei 87.22
  ORGANISM  Streptomyces scabiei 87.22
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:54:05
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 18465
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18465
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2335:11226]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2336..11226
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..18465
                     /SMILES="NC(Cc1ccccc1)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..18465
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002089"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..18465
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(101..1288)
                     /gene="txtC"
                     /locus_tag="SCAB_31761"
     CDS             complement(101..1288)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAB_31761"
                     /db_xref="EnsemblGenomes-Tr:CBG70274"
                     /db_xref="GOA:C9ZDB8"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002397"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="UniProtKB/TrEMBL:C9ZDB8"
                     /gene="txtC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 371.4; E-value:
                     8.9e-113)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SCAB_31761"
                     /note="PMID: 11889110; PMID: 15686551; PMID: 11988517;
                     thaxtomin synthesis monooxygenase probably involved in
                     pathogenicity"
                     /product="putative monooxygenase"
                     /protein_id="CBG70274.1"
                     /sec_met_domain="p450 (E-value: 6.2e-28, bitscore: 87.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESPATQVDPANSPLEPYHIYPEAKSCPVAKVGLWNGTPAHVFSG
                     YEDVRTVLQDRRFSSDSRRPNFTELTPTLQSQAAAPPFVRTDNPDHRRLRGTIAREFLP
                     KHIELLRPAIREIVQGVLDGLAETAPPQDMLEAFAVPVASATVFRLLGIPAEDRALLTR
                     CVKGVVSAVGSEDEGAEVFRTLGEYIGGLVQDPSELPEDSLIRRLVTGPYQEKQLTFHE
                     TIGVILMLIVGGYDTTASTISLSLVSYALQPEKFSVVHEHPERIPLLVEELLRYHTVSQ
                     LGLGRIATEDVEVGGVTVRAGQMVVAALPLANRDESVFPNPDELDFDRPSVPHVGFGYG
                     PHQCVGQALARVELQEAIPAVIRRLPGMRLACALEDLPFRHDMATYGIHELPMTW"
     misc_feature    complement(104..1288)
                     /gene="txtC"
                     /inference="protein motif:PFAM:PF00067"
                     /locus_tag="SCAB_31761"
                     /note="HMMPfam hit to PF00067, Cytochrome P450, score
                     6.4e-10"
     misc_feature    complement(251..280)
                     /gene="txtC"
                     /inference="protein motif:Prosite:PS00086"
                     /locus_tag="SCAB_31761"
                     /note="PS00086 Cytochrome P450 cysteine heme-iron ligand
                     signature."
     gene            complement(order(1351..1443,1447..1500))
                     /locus_tag="SCAB_31762"
                     /pseudo=""
     CDS             complement(join(1351..1443,1447..1500))
                     /codon_start=1
                     /locus_tag="SCAB_31762"
                     /note="pseudo: inframe stop after codon 18"
                     /product="putative pseudogene (fragment)"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTASHGTYGGFTEPDLQDREYYRDNAARLSRVKAACDPDRFFSFD
                     QAV"
     misc_feature    complement(1354..1482)
                     /note="Pfam BBE PF08031 codons 7-48, Bits=21.90,
                     Evalue=0.0001"
     misc_feature    1394..2017
                     /note="in/del relative to S. turgidiscabies"
     gene            complement(1722..1958)
                     /locus_tag="SCAB_31763"
                     /pseudo=""
     CDS             complement(1722..1958)
                     /codon_start=1
                     /locus_tag="SCAB_31763"
                     /note="pseudo: missing stop codon"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVSLPMVSYGTDAAPAPVVVPKAGRGRAKRLGGAGPAGWGTSVPH
                     PAERRTTETDCLGAMLETFRKPGESGVGADEGSC"
     gene            complement(2049..2246)
                     /gene="txtH"
                     /locus_tag="SCAB_31771"
     CDS             complement(2049..2246)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAB_31771"
                     /db_xref="EnsemblGenomes-Tr:CBG70277"
                     /db_xref="InterPro:IPR005153"
                     /db_xref="UniProtKB/TrEMBL:C9ZDB9"
                     /gene="txtH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009:mbtH-like protein (Score: 101.5; E-value:
                     2.5e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SCAB_31771"
                     /note="PMID: 16208464; PMID: 16408310; strong match to S.
                     turgidiscabies pathogenicity island"
                     /product="putative MbtH-like antibiotic biosynthesis
                     related protein"
                     /protein_id="CBG70277.1"
                     /transl_table=11
                     /translation="MPSPFDDHDGQFHVLRNEEGQFSLWPNFADIPSGWRSVSGPSPRG
                     SALEYIEKEWTDMRPASVRE"
     misc_feature    complement(2052..2240)
                     /gene="txtH"
                     /inference="protein motif:PFAM:PF03621"
                     /locus_tag="SCAB_31771"
                     /note="HMMPfam hit to PF03621, MbtH-like protein, score
                     5.5e-28"
     gene            complement(2336..6802)
                     /gene="txtB"
                     /locus_tag="SCAB_31781"
     CDS             complement(2336..6802)
                     /NRPS_PKS="Domain: AMP-binding (32-431). E-value: 2.9e-102.
                     Score: 334.1. Matches aSDomain:
                     nrpspksdomains_SCAB_31781_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (520-742). E-value: 2.2e-124. Score:
                     406.9. Matches aSDomain: nrpspksdomains_SCAB_31781_nMT.1"
                     /NRPS_PKS="Domain: PCP (947-1012). E-value: 1.7e-20. Score:
                     64.9. Matches aSDomain: nrpspksdomains_SCAB_31781_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1030-1332). E-value:
                     7.4e-104. Score: 338.8. Matches aSDomain:
                     nrpspksdomains_SCAB_31781_Condensation_LCL.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAB_31781"
                     /db_xref="EnsemblGenomes-Tr:CBG70278"
                     /db_xref="GOA:C9ZDC0"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/TrEMBL:C9ZDC0"
                     /gene="txtB"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     370.2; E-value: 3e-112)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SCAB_31781"
                     /note="PMID: 11115114; PMID: 15686551; PMID: 10780924;
                     thaxtomin synthesis - pathogenicity associated"
                     /product="thaxtomin synthetase B"
                     /protein_id="CBG70278.1"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-117, bitscore:
                     381.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-15, bitscore:
                     47.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.5e-69, bitscore:
                     222.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMLPPGRSRTTASPAGAQAGPEFTPGLWGRLFEARVDAAPESTA
                     INSASERLSYAELNRRANRLARLLIARGAGPESLVGLALPRSTDFVVAVAAVLKSGAGY
                     FPMDPDYPPQRLAFMLADAAPMLVLTRSDIEPELPAEAASRTVVLDDPAVVRTLADCSA
                     ADVADDERGAPLRTRHPAYVIYTSGSTGTPKGVVLTHHGIASLVGSHARDLGIGPSSRL
                     LLFSSPSFDGAFWDVSMALLTGATLVVAPRERLLPGPEFSALAAEEGITHFTLPASTLA
                     ALPDGALPAGATVVNVGEACNSELVRRWSPGRLLVNAYGPTESTVSATMSGPLAGAGIP
                     PIGRPLSDTRIHVLDERLRPVPPGAVGEIHIAGAGLARGYLGRPALTAERFVADPFGTP
                     GERMYRTGDRVRVRDDGQLEFVGRVDDQAKIRGFRVEPGEVEAVLRDHPEVAQAAVVVR
                     EDTPGDQRLVAYVVPDHPAVRQADDTTSEHVEEWQRLYDEVYSAVGALPLGEDFSGWNS
                     TYDGEPIPVPQMQAWRDATVDSIRALRPRRVLEIGVGTGLLLSRLAGDCEAYWATDFSA
                     EVIETLGKKVDVDPVLREKVHLLHGPAHDLPGLPEGYFDTVVLNSVIQYFPSADYLVSV
                     LREAARLLAPGGRVFVGDIRHLRLLRPLRSAVRLRSATRREASASAVRAAVEQDLVDEK
                     ELLLDPAFFAAVPRWIPQLRGVRTAVQRGTHHNELTRYRYDAVLIKEPVETGTAAPDAQ
                     TLTWGTDVSGLQELSGLLARTRTSLLLRGVPNSRILGEASAATALTTARSLDEPLRLLQ
                     EPAAGIDPEELHALGGGAGCEVHLTWSAQDPTRLDACFTPVGGEPGAVPLAESADSGRT
                     SPGDHANQPTTHRTGNALMGKLPGYLAARLPAYLRPSAVVRIASLPLTVNGKLDRTALP
                     RPALFPRADGQAPRTPREEILANLFADVLGLPGVPRDADFFALGGNSLLATRLVGRIAK
                     HLEVDVPIAWIFETPTVEGLAGRTAPASRLRPLLLCRDENHAAVPLSHSQYGMWFINQL
                     GGPASRIYNVPYCLRITGRVDTGALRTALDDVVARHEPLRTVFPDDGDGPRQRVLAPED
                     AAVVLHETDAAEDRLAGHLARAAAEPFELRTDLPLRARLFRHGQDRYTLLLLMHHITVD
                     AWSLAPLTADLAHAYRARLGQRAPQWQPLPVHYRDYAVWHNEQAAEAQDRGSGFGRQLA
                     FWERTLRGLPVETRLPADRSRPARPTYRGGTVHTHVEASLHQELLNCARETGATLFMVL
                     HAALAALLTRLGGGTDIVVGTAAAARTDPALDDLVGLFANSVVLRVDTSGDPTFRTLLA
                     RTRAVDLDAFTHQEVPFDQVVDRVNPARHPARHPLYQTALVLHAPPGDGHRADSVTLTP
                     EPPPNTGTARFDLMFNWDESRDSAGLAQGLTGRTEYSSDLFSQETVELLLERYLLLLSA
                     AVRDPDARLHTLDILTEPERRAFSPRP"
     CDS_motif       complement(2648..2767)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31781_0009"
                     /evalue="1.30E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="SCAB_31781"
                     /protein_end="1385"
                     /protein_start="1345"
                     /score="49.7"
                     /tool="antismash"
                     /translation="RAVDLDAFTHQEVPFDQVVDRVNPARHPARHPLYQTALVL"
     misc_feature    complement(2804..3718)
                     /gene="txtB"
                     /inference="protein motif:PFAM:PF00668"
                     /locus_tag="SCAB_31781"
                     /note="HMMPfam hit to PF00668, Condensation domain, score
                     2.3e-71"
     aSDomain        complement(2807..3712)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCAB_31781_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="7.40E-104"
                     /label="SCAB_31781_Condensation_LCL.1"
                     /locus_tag="SCAB_31781"
                     /protein_end="1332"
                     /protein_start="1030"
                     /score="338.8"
                     /tool="antismash"
                     /translation="AAVPLSHSQYGMWFINQLGGPASRIYNVPYCLRITGRVDTGALRT
                     ALDDVVARHEPLRTVFPDDGDGPRQRVLAPEDAAVVLHETDAAEDRLAGHLARAAAEPF
                     ELRTDLPLRARLFRHGQDRYTLLLLMHHITVDAWSLAPLTADLAHAYRARLGQRAPQWQ
                     PLPVHYRDYAVWHNEQAAEAQDRGSGFGRQLAFWERTLRGLPVETRLPADRSRPARPTY
                     RGGTVHTHVEASLHQELLNCARETGATLFMVLHAALAALLTRLGGGTDIVVGTAAAART
                     DPALDDLVGLFANSVVLRVDT"
     CDS_motif       complement(2816..2905)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31781_0008"
                     /evalue="2.60E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="SCAB_31781"
                     /protein_end="1329"
                     /protein_start="1299"
                     /score="39.1"
                     /tool="antismash"
                     /translation="DIVVGTAAAARTDPALDDLVGLFANSVVLR"
     CDS_motif       complement(3176..3211)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31781_0007"
                     /evalue="3.90E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="SCAB_31781"
                     /protein_end="1209"
                     /protein_start="1197"
                     /score="10.1"
                     /tool="antismash"
                     /translation="HYRDYAVWHNEQ"
     CDS_motif       complement(3260..3325)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31781_0006"
                     /evalue="4.20E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="SCAB_31781"
                     /protein_end="1181"
                     /protein_start="1159"
                     /score="22.6"
                     /tool="antismash"
                     /translation="MHHITVDAWSLAPLTADLAHAY"
     CDS_motif       complement(3527..3640)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31781_0005"
                     /evalue="2.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="SCAB_31781"
                     /protein_end="1092"
                     /protein_start="1054"
                     /score="58.6"
                     /tool="antismash"
                     /translation="IYNVPYCLRITGRVDTGALRTALDDVVARHEPLRTVFP"
     misc_feature    complement(3764..3958)
                     /gene="txtB"
                     /inference="protein motif:PFAM:PF00550"
                     /locus_tag="SCAB_31781"
                     /note="HMMPfam hit to PF00550, Phosphopantetheine
                     attachment site, score 2e-16"
     aSDomain        complement(3767..3961)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCAB_31781_PCP.1"
                     /evalue="1.70E-20"
                     /label="SCAB_31781_PCP.1"
                     /locus_tag="SCAB_31781"
                     /protein_end="1012"
                     /protein_start="947"
                     /score="64.9"
                     /tool="antismash"
                     /translation="EEILANLFADVLGLPGVPRDADFFALGGNSLLATRLVGRIAKHLE
                     VDVPIAWIFETPTVEGLAGR"
     aSModule        complement(3767..6706)
                     /complete
                     /domains="nrpspksdomains_SCAB_31781_AMP-binding.1"
                     /domains="nrpspksdomains_SCAB_31781_nMT.1"
                     /domains="nrpspksdomains_SCAB_31781_PCP.1"
                     /locus_tags="SCAB_31781"
                     /monomer_pairings="X -> NMe-X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     misc_feature    complement(3842..3889)
                     /gene="txtB"
                     /inference="protein motif:Prosite:PS00012"
                     /locus_tag="SCAB_31781"
                     /note="PS00012 Phosphopantetheine attachment site."
     aSDomain        complement(4577..5242)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCAB_31781_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="2.20E-124"
                     /label="SCAB_31781_nMT.1"
                     /locus_tag="SCAB_31781"
                     /protein_end="742"
                     /protein_start="520"
                     /score="406.9"
                     /tool="antismash"
                     /translation="GEPIPVPQMQAWRDATVDSIRALRPRRVLEIGVGTGLLLSRLAGD
                     CEAYWATDFSAEVIETLGKKVDVDPVLREKVHLLHGPAHDLPGLPEGYFDTVVLNSVIQ
                     YFPSADYLVSVLREAARLLAPGGRVFVGDIRHLRLLRPLRSAVRLRSATRREASASAVR
                     AAVEQDLVDEKELLLDPAFFAAVPRWIPQLRGVRTAVQRGTHHNELTRYRYDAVLIKEP
                     "
     misc_feature    complement(4850..5158)
                     /gene="txtB"
                     /inference="protein motif:PFAM:PF08241"
                     /locus_tag="SCAB_31781"
                     /note="HMMPfam hit to PF08241, Methyltransferase domain,
                     score 1.6e-22"
     misc_feature    complement(4856..5158)
                     /gene="txtB"
                     /inference="protein motif:PFAM:PF08242"
                     /locus_tag="SCAB_31781"
                     /note="HMMPfam hit to PF08242, Methyltransferase domain,
                     score 7.6e-21"
     CDS_motif       complement(5114..5149)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31781_0004"
                     /evalue="1.40E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="SCAB_31781"
                     /protein_end="563"
                     /protein_start="551"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="GVGTGLLLSRLA"
     misc_feature    complement(5438..6643)
                     /gene="txtB"
                     /inference="protein motif:PFAM:PF00501"
                     /locus_tag="SCAB_31781"
                     /note="HMMPfam hit to PF00501, AMP-binding enzyme, score
                     5.4e-157"
     CDS_motif       complement(5480..5545)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31781_0003"
                     /evalue="3.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="SCAB_31781"
                     /protein_end="441"
                     /protein_start="419"
                     /score="35.2"
                     /tool="antismash"
                     /translation="FVGRVDDQAKIRGFRVEPGEVE"
     aSDomain        complement(5510..6706)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCAB_31781_AMP-binding.1"
                     /evalue="2.90E-102"
                     /label="SCAB_31781_AMP-binding.1"
                     /locus_tag="SCAB_31781"
                     /protein_end="431"
                     /protein_start="32"
                     /score="334.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEARVDAAPESTAINSASERLSYAELNRRANRLARLLIARGAGPE
                     SLVGLALPRSTDFVVAVAAVLKSGAGYFPMDPDYPPQRLAFMLADAAPMLVLTRSDIEP
                     ELPAEAASRTVVLDDPAVVRTLADCSAADVADDERGAPLRTRHPAYVIYTSGSTGTPKG
                     VVLTHHGIASLVGSHARDLGIGPSSRLLLFSSPSFDGAFWDVSMALLTGATLVVAPRER
                     LLPGPEFSALAAEEGITHFTLPASTLAALPDGALPAGATVVNVGEACNSELVRRWSPGR
                     LLVNAYGPTESTVSATMSGPLAGAGIPPIGRPLSDTRIHVLDERLRPVPPGAVGEIHIA
                     GAGLARGYLGRPALTAERFVADPFGTPGERMYRTGDRVRVRDDGQLEFVGRVDDQAKIR
                     "
     CDS_motif       complement(5630..5719)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31781_0002"
                     /evalue="2.20E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="SCAB_31781"
                     /protein_end="391"
                     /protein_start="361"
                     /score="55.1"
                     /tool="antismash"
                     /translation="PPGAVGEIHIAGAGLARGYLGRPALTAERF"
     CDS_motif       complement(6203..6262)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31781_0001"
                     /evalue="1.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="SCAB_31781"
                     /protein_end="200"
                     /protein_start="180"
                     /score="33.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVVLTH"
     misc_feature    complement(6221..6256)
                     /gene="txtB"
                     /inference="protein motif:Prosite:PS00455"
                     /locus_tag="SCAB_31781"
                     /note="PS00455 Putative AMP-binding domain signature."
     gene            complement(6850..11226)
                     /gene="txtA"
                     /locus_tag="SCAB_31791"
     CDS             complement(6850..11226)
                     /NRPS_PKS="Domain: AMP-binding (22-421). E-value: 5.8e-106.
                     Score: 346.3. Matches aSDomain:
                     nrpspksdomains_SCAB_31791_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (511-732). E-value: 5.2e-125. Score:
                     409.0. Matches aSDomain: nrpspksdomains_SCAB_31791_nMT.1"
                     /NRPS_PKS="Domain: PCP (940-1007). E-value: 1.3e-21. Score:
                     68.5. Matches aSDomain: nrpspksdomains_SCAB_31791_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1025-1325). E-value:
                     6.6e-89. Score: 289.7. Matches aSDomain:
                     nrpspksdomains_SCAB_31791_Condensation_LCL.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAB_31791"
                     /db_xref="EnsemblGenomes-Tr:CBG70279"
                     /db_xref="GOA:C9ZDC1"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/TrEMBL:C9ZDC1"
                     /gene="txtA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 70.5; E-value:
                     2.5e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SCAB_31791"
                     /note="PMID: 11115114; PMID: 15686551; thaxtomin synthesis
                     - pathogenicity associated"
                     /product="thaxtomin synthetase A"
                     /protein_id="CBG70279.1"
                     /sec_met_domain="AMP-binding (E-value: 7.8e-119, bitscore:
                     386.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-17, bitscore:
                     54.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.9e-56, bitscore:
                     180.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHLTGEDLPEGALATTWPSLLEARVADTPDAIALVAGDTALTYA
                     QFNARANRLARWLKYLGAGPERSVGLVLGRSADFFLCATAVLKCGAAYLPLDPNYPVER
                     LSFMARDAAPVVLVTTSDVRGDLLGQLPTGSLVVLDDEATEDVLRRLPDHDMEDGERLE
                     PLRPASPAYIIYTSGSTGIPKGVVVTHQGVASLIATQRRRLAVTGASRVLAFSSPSFDA
                     SFWEMSMALLAGAALVVGRPGRLLPDAELAALIADHGVTHVTLPPSVAGALGPDMLPPS
                     VTLVVAGEACPAALVQRWRPHRTMVNAYGPTESTVCATMSDPLADDVAPPVGRAVDGTR
                     IHVLDDRLAPVVPGAVGEIYIAGHSLARGYLERPGLTAQRFVADPFGPAGSRMYRSGDL
                     GRWTRSGDLEFVGRADDQVKVRGFRIEPGEIESVIAGCRGVRQAAVVLREDRPGEPYLA
                     AYVIPENAAADEAAGEEPDGQLDAWRRLYDDLYGRADTADFGEDFSGWVSSYGGRPIEG
                     MREWREQTVRQIRELAPRRVLEIGCGSGLLLSQLAGDCESYWGTDISGALIERLRGQVA
                     ERPGLADRVVLHQLSAHELGSLPSGGFDTVVLNSVIQYFPSGDYLFDLLREVSRLLVPG
                     GAVFLGDVRNLRLLRTFHAGGLLAAATHTDTPQTVCAAIDRAMAQEKELLVDPEFFTTA
                     VGALPGMTLESCTLKRGGYDNELSRYRYEVVLRKHAGPADDTGPTDDAGPVVRLRWDGE
                     MASLADVADRLRRGKPERLCVTGIPNGRVAGEHAATLALFDRRPLHEVLSLGQAPAGVA
                     PEDLRRLGAELGYRVDCTWSSEDDALIDASFTRAGALVPRPAPRTDAEPDGFSPARFTN
                     RPAFARPDSQTMASLPGQVAAKLPAFMVPEVFVPLDRLPVTVNGKLDRGALPRPRRAAH
                     ASGRPPRTAREEVLAAIFADVLATADVTADSDFFAVGGNSLLATRLAAEVRRRLNTEMP
                     LSWLFESPTVGALAARFDAGDEARPLPVPSEYASGSTAPLSAQQMQMWHEYRRSLCRDM
                     FNVPLSQRLTGAVDAEALRAALADVVTRHVPLRTLVQDDGSGPCAVITEATADDIPWTE
                     TRTTPERLSEDLAHAARRHFDLETEIPLRAVLFTLGPDESVLLLVMHHIAADGWSFGPL
                     LEDLVRAYRARTEGRAPQWEPLSFGYLDYVAWQRRLLGATDDPSDVALRQAEYWRKTLH
                     GADDRPVLETDSPAPAQQDFAGRSLDLPLEVGGHRVLTAAAREHGVTVFMILHAALVAL
                     LARRGAGGDVTVVTAVAGRTDTQFEPLVGLFANTLALRTDTSGNPTFRELLDRVRVTDL
                     GAYAHQDLLFERLADVPPPQVSLVLRTVAAPPADLPGLTISPGPRPASESARYPVLWTV
                     EHLASAADGGTLRSHIQYQSGLLRDDTVVRLAQQYEVVLSLLLKDPDLRVQDLPLQ"
     misc_feature    complement(7249..8160)
                     /gene="txtA"
                     /inference="protein motif:PFAM:PF00668"
                     /locus_tag="SCAB_31791"
                     /note="HMMPfam hit to PF00668, Condensation domain, score
                     1.7e-53"
     aSDomain        complement(7252..8151)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCAB_31791_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.60E-89"
                     /label="SCAB_31791_Condensation_LCL.1"
                     /locus_tag="SCAB_31791"
                     /protein_end="1325"
                     /protein_start="1025"
                     /score="289.7"
                     /tool="antismash"
                     /translation="TAPLSAQQMQMWHEYRRSLCRDMFNVPLSQRLTGAVDAEALRAAL
                     ADVVTRHVPLRTLVQDDGSGPCAVITEATADDIPWTETRTTPERLSEDLAHAARRHFDL
                     ETEIPLRAVLFTLGPDESVLLLVMHHIAADGWSFGPLLEDLVRAYRARTEGRAPQWEPL
                     SFGYLDYVAWQRRLLGATDDPSDVALRQAEYWRKTLHGADDRPVLETDSPAPAQQDFAG
                     RSLDLPLEVGGHRVLTAAAREHGVTVFMILHAALVALLARRGAGGDVTVVTAVAGRTDT
                     QFEPLVGLFANTLALRTDT"
     CDS_motif       complement(7261..7350)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31791_0007"
                     /evalue="8.20E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="SCAB_31791"
                     /protein_end="1322"
                     /protein_start="1292"
                     /score="34.3"
                     /tool="antismash"
                     /translation="DVTVVTAVAGRTDTQFEPLVGLFANTLALR"
     CDS_motif       complement(7705..7770)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31791_0006"
                     /evalue="9.70E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="SCAB_31791"
                     /protein_end="1174"
                     /protein_start="1152"
                     /score="34.1"
                     /tool="antismash"
                     /translation="MHHIAADGWSFGPLLEDLVRAY"
     CDS_motif       complement(7981..8085)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31791_0005"
                     /evalue="2.10E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="SCAB_31791"
                     /protein_end="1082"
                     /protein_start="1047"
                     /score="36.2"
                     /tool="antismash"
                     /translation="MFNVPLSQRLTGAVDAEALRAALADVVTRHVPLRT"
     aSDomain        complement(8206..8406)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCAB_31791_PCP.1"
                     /evalue="1.30E-21"
                     /label="SCAB_31791_PCP.1"
                     /locus_tag="SCAB_31791"
                     /protein_end="1007"
                     /protein_start="940"
                     /score="68.5"
                     /tool="antismash"
                     /translation="EEVLAAIFADVLATADVTADSDFFAVGGNSLLATRLAAEVRRRLN
                     TEMPLSWLFESPTVGALAARFD"
     aSModule        complement(8206..11160)
                     /complete
                     /domains="nrpspksdomains_SCAB_31791_AMP-binding.1"
                     /domains="nrpspksdomains_SCAB_31791_nMT.1"
                     /domains="nrpspksdomains_SCAB_31791_PCP.1"
                     /locus_tags="SCAB_31791"
                     /monomer_pairings="Phe -> NMe-Phe"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     misc_feature    complement(8209..8403)
                     /gene="txtA"
                     /inference="protein motif:PFAM:PF00550"
                     /locus_tag="SCAB_31791"
                     /note="HMMPfam hit to PF00550, Phosphopantetheine
                     attachment site, score 8e-17"
     misc_feature    complement(8287..8334)
                     /gene="txtA"
                     /inference="protein motif:Prosite:PS00012"
                     /locus_tag="SCAB_31791"
                     /note="PS00012 Phosphopantetheine attachment site."
     aSDomain        complement(9031..9693)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCAB_31791_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="5.20E-125"
                     /label="SCAB_31791_nMT.1"
                     /locus_tag="SCAB_31791"
                     /protein_end="732"
                     /protein_start="511"
                     /score="409.0"
                     /tool="antismash"
                     /translation="GRPIEGMREWREQTVRQIRELAPRRVLEIGCGSGLLLSQLAGDCE
                     SYWGTDISGALIERLRGQVAERPGLADRVVLHQLSAHELGSLPSGGFDTVVLNSVIQYF
                     PSGDYLFDLLREVSRLLVPGGAVFLGDVRNLRLLRTFHAGGLLAAATHTDTPQTVCAAI
                     DRAMAQEKELLVDPEFFTTAVGALPGMTLESCTLKRGGYDNELSRYRYEVVLRKHAGP"
     misc_feature    complement(9307..9615)
                     /gene="txtA"
                     /inference="protein motif:PFAM:PF08241"
                     /locus_tag="SCAB_31791"
                     /note="HMMPfam hit to PF08241, Methyltransferase domain,
                     score 7.7e-16"
     misc_feature    complement(9313..9615)
                     /gene="txtA"
                     /inference="protein motif:PFAM:PF08242"
                     /locus_tag="SCAB_31791"
                     /note="HMMPfam hit to PF08242, Methyltransferase domain,
                     score 1.7e-20"
     misc_feature    complement(9892..11100)
                     /gene="txtA"
                     /inference="protein motif:PFAM:PF00501"
                     /locus_tag="SCAB_31791"
                     /note="HMMPfam hit to PF00501, AMP-binding enzyme, score
                     2e-156"
     CDS_motif       complement(9934..9999)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31791_0004"
                     /evalue="7.50E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="SCAB_31791"
                     /protein_end="431"
                     /protein_start="409"
                     /score="40.3"
                     /tool="antismash"
                     /translation="FVGRADDQVKVRGFRIEPGEIE"
     aSDomain        complement(9964..11160)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SCAB_31791_AMP-binding.1"
                     /evalue="5.80E-106"
                     /label="SCAB_31791_AMP-binding.1"
                     /locus_tag="SCAB_31791"
                     /protein_end="421"
                     /protein_start="22"
                     /score="346.3"
                     /specificity="substrate consensus: Phe"
                     /tool="antismash"
                     /translation="EARVADTPDAIALVAGDTALTYAQFNARANRLARWLKYLGAGPER
                     SVGLVLGRSADFFLCATAVLKCGAAYLPLDPNYPVERLSFMARDAAPVVLVTTSDVRGD
                     LLGQLPTGSLVVLDDEATEDVLRRLPDHDMEDGERLEPLRPASPAYIIYTSGSTGIPKG
                     VVVTHQGVASLIATQRRRLAVTGASRVLAFSSPSFDASFWEMSMALLAGAALVVGRPGR
                     LLPDAELAALIADHGVTHVTLPPSVAGALGPDMLPPSVTLVVAGEACPAALVQRWRPHR
                     TMVNAYGPTESTVCATMSDPLADDVAPPVGRAVDGTRIHVLDDRLAPVVPGAVGEIYIA
                     GHSLARGYLERPGLTAQRFVADPFGPAGSRMYRSGDLGRWTRSGDLEFVGRADDQVKVR
                     "
     CDS_motif       complement(10084..10170)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31791_0003"
                     /evalue="3.00E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="SCAB_31791"
                     /protein_end="381"
                     /protein_start="352"
                     /score="48.3"
                     /tool="antismash"
                     /translation="PGAVGEIYIAGHSLARGYLERPGLTAQRF"
     CDS_motif       complement(10657..10716)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31791_0002"
                     /evalue="6.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="SCAB_31791"
                     /protein_end="190"
                     /protein_start="170"
                     /score="30.9"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGIPKGVVVTH"
     misc_feature    complement(10675..10710)
                     /gene="txtA"
                     /inference="protein motif:Prosite:PS00455"
                     /locus_tag="SCAB_31791"
                     /note="PS00455 Putative AMP-binding domain signature."
     CDS_motif       complement(10936..10974)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SCAB_31791_0001"
                     /evalue="1.00E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="SCAB_31791"
                     /protein_end="97"
                     /protein_start="84"
                     /score="15.6"
                     /tool="antismash"
                     /translation="AVLKCGAAYLPLD"
     misc_feature    11252..11509
                     /note="alternative in/del in S. scabies compared with S.
                     turgidiscabies pathogenicity island; 257 bases here vs 1484
                     bases in S. turgidiscabies"
     misc_feature    11616..11634
                     /note="possible iron-dependent repressor binding site?"
     misc_feature    12167..12763
                     /note="alternative in/del?"
     gene            12898..13746
                     /gene="txtR"
                     /locus_tag="SCAB_31801"
     CDS             12898..13746
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAB_31801"
                     /db_xref="EnsemblGenomes-Tr:CBG70280"
                     /db_xref="GOA:C9ZDC2"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR018060"
                     /db_xref="UniProtKB/TrEMBL:C9ZDC2"
                     /gene="txtR"
                     /gene_functions="regulatory (smcogs) SMCOG1015:AraC family
                     transcriptional regulator (Score: 62.9; E-value: 6.1e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="SCAB_31801"
                     /note="PMID: 15686551; PMID:11004184; PMID:8631685; PMID:
                     17919290; no significant Pfam domain matches; strong match
                     to S. turgidiscabies pathogenicity island; TTA-Leu codon(s)
                     203 may indicate regulation by BldA"
                     /product="cellobiose-dependent regulator TxtR"
                     /protein_id="CBG70280.1"
                     /transl_table=11
                     /translation="MSSSGMQIKSFKAGGVKVTIIDSGPAVIEFEAINSEAALTPQRTV
                     ICVLSGMAFIAGTGNGTEIDAGTLVMTDGDVPFSMNVPVASRLLVLRFADEAKDGLPVS
                     PRGTFIVTDAAKGPGSGFLFSFLNTLAVEMMKTDGILSSYMEEVVRILAISATRIAYAE
                     LGKHYSGGCDPLLIAVQESIDRQLADPEISPATLAAEHNISVRQLHRVFGPIGESVMSY
                     VKRRRLERFACDLRDPSLGHRKINELAADWGMLDAAMLSRHFRCAYGMSPRDYRKQHCF
                     T"
     regulatory      13519..13521
                     /gene="txtR"
                     /locus_tag="SCAB_31801"
                     /note="TTA_Leu (rare) indicates regulation by availability
                     of BldA"
                     /regulatory_class="other"
     misc_feature    13519..13521
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13778..15409
                     /note="alternative in/del compared to S. turgidiscabies
                     pathogenicity island; 1631 bases here vs 3557 bases in S.
                     turgidiscabies"
     gene            complement(14324..14569)
                     /locus_tag="SCAB_31811"
                     /pseudo=""
     CDS             complement(14324..14569)
                     /codon_start=1
                     /db_xref="PSEUDO:CBG70281.1"
                     /locus_tag="SCAB_31811"
                     /note="pseudo: gene fragment"
                     /product="conserved hypothetical protein (fragment)"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEDLSVAGLARTKLTKSVHDAGWPSFLSMLEYKAERYGRTLVRIG
                     RFTPTSQTCSRPRGSCRSSRDADPWGSPDRVAVTPY"
     gene            14944..15345
                     /locus_tag="SCAB_31812"
                     /pseudo=""
     CDS             14944..15345
                     /codon_start=1
                     /db_xref="PSEUDO:CBG70282.1"
                     /locus_tag="SCAB_31812"
                     /note="pseudo: fragment"
                     /product="conserved hypothetical protein (fragment)"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRYTVRCNRHLPRRLVFCRLPQHRGILNVHLAYGMRQFIARQDWP
                     TRYRLVSYAPGLNPAEGFWSPLRSRTAFTTLRAPQPDHRNGMRKSGMFPTHRRMPRRNR
                     SVPHANDLTSSVAVRTRENLQFPPGFTGI"
     gene            complement(15494..15715)
                     /locus_tag="SCAB_31821"
     CDS             complement(15494..15715)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAB_31821"
                     /db_xref="EnsemblGenomes-Tr:CBG70283"
                     /db_xref="UniProtKB/TrEMBL:C9ZDC5"
                     /locus_tag="SCAB_31821"
                     /note="strong match to S. turgidiscabies pathogenicity
                     island: no matches in uniprot db; frame plot is wrong
                     -doubtful CDS"
                     /product="hypothetical protein"
                     /protein_id="CBG70283.1"
                     /transl_table=11
                     /translation="MASGGDSQVPFGAEIGFSDEDLSYCVRATGLLDQEAAHRRTTLTC
                     VACPGDGGAVAPEFLSLEDRAPAHLHHG"
     gene            15909..17129
                     /locus_tag="SCAB_31831"
     CDS             15909..17129
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAB_31831"
                     /db_xref="EnsemblGenomes-Tr:CBG70284"
                     /db_xref="GOA:C9ZDC6"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002397"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="PDB:4L36"
                     /db_xref="PDB:4TPN"
                     /db_xref="PDB:4TPO"
                     /db_xref="UniProtKB/TrEMBL:C9ZDC6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 268.7; E-value: 1.4e-81)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SCAB_31831"
                     /note="PMID: 15686551; strong match to S. turgidiscabies
                     pathogenicity island"
                     /product="putative P450-like protein"
                     /protein_id="CBG70284.1"
                     /sec_met_domain="p450 (E-value: 3.7e-17, bitscore: 51.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPSPLADPSIVPDPYPVYADLAQRRPVHWVERLNAWAVLTYAD
                     CAAGLKDPRLTADRGTEVLAAKFPGQPLPPDNIFHRWTKNVVMYTDPPLHDALRRSVRA
                     GFTRAAHQHYDQVLQKVAHDLVASIPAGATEIDAVPALAAELPVRSAVHAFGVPEEDLG
                     FLIPRVNTIMTYHSGPKDQPVTQEIILEKLTDLHTYASELLQGMRGKVLPDTVIARLAA
                     AQDGLTETTPEQTVHQLALVFIALFAPTTPGSLSSGTLAFARNPRQVERFLADQACVDN
                     TANEVLRYNASNQFTWRVAAKDVEMGGVRIEAGQTLALFLGSANRDANMFERPNDFDLD
                     RPNSARHLSFGQGVHACLAAQLISLQLKWFYVALLNRFPGIRTAGEPIWNENLEFRSLR
                     SLPLSLR"
     misc_feature    16800..16982
                     /locus_tag="SCAB_31831"
                     /note="subthreshold Pfam fragment PF00067 p450, codons
                     298-358, Bits=19.10, Evalue=4.5e-06"
     misc_feature    16956..16985
                     /inference="protein motif:Prosite:PS00086"
                     /locus_tag="SCAB_31831"
                     /note="PS00086 Cytochrome P450 cysteine heme-iron ligand
                     signature."
     gene            17193..18365
                     /gene="txtD"
                     /gene_synonym="nos"
                     /locus_tag="SCAB_31841"
     CDS             17193..18365
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAB_31841"
                     /db_xref="EnsemblGenomes-Tr:CBG70285"
                     /db_xref="GOA:C9ZDC7"
                     /db_xref="InterPro:IPR004030"
                     /db_xref="InterPro:IPR017142"
                     /db_xref="UniProtKB/TrEMBL:C9ZDC7"
                     /gene="txtD"
                     /gene_synonym="nos"
                     /locus_tag="SCAB_31841"
                     /note="PMID: 15686551; PMID: 15129284; strong match to S.
                     turgidiscabies pathogenicity island"
                     /product="putative oxygenase"
                     /protein_id="CBG70285.1"
                     /transl_table=11
                     /translation="MPAPSPTACPALGPDSSLGPVPSAEPATPQSCGVADPNEAEEFLR
                     QFHAEQSDQPVPLARRLEQVRAAIDATGTYRHTTAELVYGARVAWRNSSRCIGRLYWNS
                     LRVLDRRDATAPDEIHRHLCTHLRQATNGGRIRPVISVFAPDSPGRPGPQVWNEQLIRY
                     AGYRRDDGTVLGDPRTADLTEAILRLGWQGCPQGPFDVLPLVIDTPDDKPRFFELPREL
                     VLEVPITHPDVPRLAELGLRWHAVPVISNMRLRIGGMDYPLAPFNGWYMGTEIGARNLV
                     DEDRYNMLPAVAACLQLDTTSESTLWRDRALVELNVAVLHSFEAAGVRISDHHEESRRF
                     LAHLAKEERQGRTVSADWSWIVPPLSGGITPVFHRYYDNVDQRPNFYPHQ"
     misc_feature    17268..18362
                     /gene="txtD"
                     /gene_synonym="nos"
                     /inference="protein motif:PFAM:PF02898"
                     /locus_tag="SCAB_31841"
                     /note="HMMPfam hit to PF02898, Nitric oxide synthase,
                     oxygenase domain, score 3.5e-146"
ORIGIN
        1 ccgagaggcg ggcgcgccgg tatgaccgcc cgctgcgctg ctccctcggc cgacgcgtcg
       61 taggcacgtg acactggtgc tcgcctcgcg gcaggcccgg tcaccaggtc atgggcagct
      121 catggatgcc gtaggtggcc atgtcgtgcc ggaacggcag gtcttccaga gcgcaggcga
      181 gccgcatgcc gggcagccgt cggatcaccg cgggaatggc ctcctggagt tcgactcggg
      241 ccagtgcctg gccgacgcac tggtggggtc cgtaaccgaa gccgacatgg ggcacggacg
      301 ggcggtcgaa gtcgagttcg tccgggttcg ggaagacact ctcgtcccgg ttggccaggg
      361 ggagcgccgc caccaccatc tggccggccc gcaccgtgac gccgcccacc tcgacgtcct
      421 cggtggcgat cctgcccagt ccgagctgcg agacggtgtg atagcgcagc aactcctcga
      481 cgagcagggg tatccgctcc gggtgttcgt ggacgacgga gaacttctcc ggctgcagtg
      541 cataactcac caaggacagc gagatggtgc tggccgtcgt gtcgtagccc ccgacgatga
      601 gcatgaggat cacgccgatg gtctcgtgga aggtgagctg cttctcctgg tacgggcccg
      661 tcaccaggcg ccggatcagg ctgtcctcgg gcagttcgga ggggtcctgg acgagcccgc
      721 cgatgtactc gccgagtgtc cggaacacct cggcaccttc gtcctcgctc cccaccgccg
      781 agaccacgcc cttgacgcat cgggtgagca acgcgcggtc ctcggccgga atccccagca
      841 gccggaagac ggtcgcggac gcgaccggta cggcgaaggc ctcgagcatg tcctggggag
      901 gcgcggtctc ggcgagcccg tcgagcacac cctggacgat ctcgcggatc gcggggcgca
      961 gcagctcgat gtgcttgggc aggaactcgc gtgcgatggt gcctcgcagg cgccggtgat
     1021 caggattgtc ggtgcgtacg aacggcggtg ccgcggcctg cgactggagc gtcggagtga
     1081 gttcggtgaa gttgggtcgg cgcgagtccg agctgaaccg cctgtcctgc agcacggtcc
     1141 gcacatcctc atacccggag aacacgtgcg ccggcgtgcc gttccacaga ccgaccttcg
     1201 ccaccgggca ggacttggcc tccgggtaga tgtgataggg ctccaacggc gagttcgccg
     1261 ggtcgacctg ggtggccgga gattccatgg tgtcgtttcc tttccaagac cgcaggcctg
     1321 ggccgtgcgg cgtcgtgacg gcgtctcgcg tcataccgcc tggtcgaaac tgaagaagcg
     1381 gtccgggtca caggccgcct tgacccggga gagccgggcg gcgttgtcgc ggtagtactc
     1441 acgtcagtcc tgcaggtccg gctcggtgaa tccgccgtag gtgccgtgcg acgcggtcgg
     1501 ctgcccaaca agtactgcgc gtccaggtgc caggacgccg tcgcggccgg gtcgacgcgg
     1561 ccatcacacg ctcgtgaccg ctgcgcccgc cgtccgtgaa cacgccgagg acggcgtcta
     1621 cgacagaacc ggcgacgggt gcggaatgga ggtcaccctt gatggcggcg gagccgacac
     1681 gtggcaggcg cgctccttcc cgggtgccca cccgatggca ggcacgaacc ctcgtcggca
     1741 cctacgccgg actcgccggg tttccggaag gtctccagca tcgcgccgag acagtccgtc
     1801 tccgtcgtcc ggcgttcggc tgggtggggc accgacgtgc cccacccagc cggtccagca
     1861 ccgcccaagc gcttcgcccg gccccggccg gccttcggga ccaccaccgg agccggtgcg
     1921 gcgtcggtgc cgtacgagac catcggcagg gacaccacgt cctcggaatc ggcggtcgcc
     1981 cagccgagcc agccgtaaac ggcccggttc tcggcgaccc gtggccccgc tcgatgttat
     2041 tggccgggtc attcacggac ggacgccggg cgcatgtccg tccattcctt ctcgatgtac
     2101 tcaagggcgc ttccgcgggg gctcggcccg ctcacggaac gccacccgga ggggatgtcg
     2161 gcgaaattcg gccagagtga gaactggcct tcctcgttgc ggagcacatg gaactgcccg
     2221 tcatggtcgt cgaagggtga gggcacggtg aatttctcct agtcggcaaa gagggcccgg
     2281 caccgggaat tgacggtgct ttcggtggct ttcgcgatga ttcggggtcg gacggctacg
     2341 gccgtggtga gaaggcccgc cgttccggct cggtgaggat gtccagggtg tgaaggcgtg
     2401 cgtccgggtc gcggaccgcg gcggacagca gcaggagata ccgctccagg agcagttcga
     2461 ctgtctcctg ggagaagagg tccgagctgt actcggtacg gccggtgagg ccctgggcga
     2521 ggccggcgct gtcccggctc tcgtcccagt tgaacatcag atcgaagcgg gccgttccgg
     2581 tgttcggggg cggttcgggg gtgagggtga cggagtcggc ccgatggccg tcgccgggcg
     2641 gtgcgtgcag gacgagggcc gtctggtaga gcgggtgacg tgccgggtgg cgtgccgggt
     2701 tgacgcgatc caccacctgg tcgaacggga cctcctggtg ggtgaaggcg tcgaggtcca
     2761 cggcccgggt ccgagcgagc agggtgcgga acgtcgggtc gcccgaggtg tcgacgcgaa
     2821 ggacgacact gttggcgaac agcccgacga ggtcgtccag cgcggggtcc gtgcgcgccg
     2881 cggcagcggt gccgacgacg atgtcggtgc cgccgcccag ccgggtcagc agtgccgcga
     2941 gcgcggcgtg cagcaccatg aagagcgtcg cgcccgtctc ccgcgcgcag ttgagcagtt
     3001 cctgatggag ggaggcttcg acgtgggtgt ggacggtgcc gccacgatag gtaggtctgg
     3061 ccggacggct ccggtcggcc ggcagccgcg tctcgaccgg aagaccgcgc agcgtccgct
     3121 cccagaaggc gagctggcgc ccgaagccgc tgccgcggtc ctgcgcctcg gctgcttgct
     3181 cgttgtgcca tacggcgtag tcgcgatagt gaaccggcag cggctgccac tgcggggccc
     3241 gctgccccag ccgcgcccgg taggcgtgcg ccaggtccgc cgtcaggggg gccagcgacc
     3301 aggcgtccac ggtgatgtgg tgcatcagga gcaggagcgt gtaccggtcc tgtccgtgcc
     3361 ggaacaggcg tgcgcgcagg ggaaggtccg tcctgagctc gaagggttcc gccgcggccc
     3421 gcgccaggtg gccggccaga cggtcttcgg cggcgtcggt ctcatgaagg accaccgcgg
     3481 cgtcctcggg ggcgaggacc cgttggcggg ggccgtcacc gtcatcgggg aagacggtac
     3541 gcaggggttc gtgacgagcc acgacgtcat cgagtgcggt ccgcagcgcc ccggtgtcca
     3601 cccggcccgt gatccgcagg cagtacggca cgttgtagat ccggctcgcg ggtccgccga
     3661 gttggttgat gaaccacatg ccgtactggc tgtgcgagag cggcaccgcc gcgtggttct
     3721 cgtcgcggca gagcaacagc gggcggagcc tgctcgccgg agcggtacgc ccggccaggc
     3781 cctcgacggt cggtgtctcg aagatccagg cgatcggaac atcgacttcg aggtgtttcg
     3841 cgatacggcc gacgaggcgc gtggccagta gcgagttgcc gcccagggcg aagaagtcgg
     3901 cgtccctcgg caccccgggc aggccgagca catcggcgaa gagattggcg aggatctcct
     3961 cgcgcggagt gcggggcgcc tgcccgtcag cccgcgggaa cagggcggga cggggcagcg
     4021 ccgtgcggtc gagcttgccg ttgacggtga gggggagcga cgcgatgcgt accacggcgc
     4081 tgggccgcag gtacgcgggg agcctggcgg ccagatagcc ggggagcttg cccatcaggg
     4141 cgttgccggt ccggtgcgtg gtcggctggt tggcgtggtc accgggcgac gtcctgccgc
     4201 tgtcggcgga ctccgccagc gggacggcgc ccggttcacc gcccacgggt gtgaaacagg
     4261 cgtccagtcg cgtggggtcc tgcgccgacc acgtgaggtg gacctcgcag ccggcgcccc
     4321 cgcccagggc gtgcagttcc tcggggtcga tccctgccgc cggttcttgc agcaaccgca
     4381 acggctcgtc gagcgaccgg gccgtggtca gcgccgtcgc ggccgatgcc tcaccgagga
     4441 tccggctgtt cggcacgccg cgcagcagca gcgacgtgcg ggtgcgggcc agcaggccgg
     4501 acaactcctg cagtccgctg acatccgtgc cccaggtcag tgtctgcgcg tccggcgcag
     4561 cggtaccggt ttccaccggc tccttgatga gcaccgcgtc gtaccggtag cgggtcagtt
     4621 cgttgtggtg cgtgccgcgc tgcaccgctg tgcgtacccc gcggagctgc gggatccacc
     4681 ggggtaccgc ggcgaagaac gcggggtcga ggagcaactc cttctcatcc accaggtcct
     4741 gctcgaccgc cgcgcggacg gcggaggcag aggcttcccg ccgggtggcg gagcgcagcc
     4801 ggacggcgct gcgcagcggg cgcagcagac gcaggtgccg gatgtcgccg acgaacaccc
     4861 ggccgcccgg cgccagcagg cgtgccgcct cgcgcaggac gctcaccagg tagtcggccg
     4921 acggaaagta ctggatcacc gagttgagga caacggtgtc gaagtacccc tcggggaggc
     4981 cggggaggtc gtgtgcggga ccgtgcagca ggtggacctt ctcccgcagc accgggtcga
     5041 cgtccacctt cttgccgagt gtctcgatca cctcggcgga gaagtcggtg gcccagtacg
     5101 cctcgcagtc accggcgagg cgggacagca gcagcccggt gcccacgccg atctccagta
     5161 cccggcgcgg tcgcagggca cggatgctgt cgaccgtggc gtcccgccag gcttgcatct
     5221 gaggcacggg aatgggctcg ccgtcgtagg tgctgttcca gccgctgaag tcctccccca
     5281 gggggagcgc tcccactgcg ctgtagacct cgtcgtagag ccgttgccat tcctcgacgt
     5341 gctccgaggt ggtgtcgtcg gcctgccgca cggccgggtg gtccggcacg acataggcga
     5401 cgagcctctg gtctcccgga gtgtcctccc ggaccaccac cgcggcctgc gcgacctcgg
     5461 gatggtcgcg cagcacggct tcgacctcgc cgggctccac tcggaaaccc cgtatcttcg
     5521 cctggtcgtc gacccggccc acgaactcca gttgcccgtc gtcacgcacc ctcacccggt
     5581 cgccggtccg gtacatccgc tcgcccggcg tcccgaaggg gtcggccacg aaccgctcgg
     5641 cggtcagcgc gggccgcccc aggtacccgc gggccagccc cgctccggcg atgtggatct
     5701 ctccgaccgc tcccggcggt accggccgga gccgctcgtc gaggacgtgg atgcgggtgt
     5761 ccgagagcgg acggccgatg ggcgggatgc ctgccccggc caacggtccg ctcatggtcg
     5821 cggagacggt cgattcggtc ggtccgtacg cgttcaccag cagccggccc ggcgaccagc
     5881 ggcgcaccag ctcgctgttg caggcctcgc ccacattgac gacggtggcc ccggcgggca
     5941 gagcgccgtc cggcagggcg gcgagcgtgg aggccggcag ggtgaagtgg gtgatgccct
     6001 cctcggcggc gagcgcactg aactccggtc cgggcaggag ccgttcacgc ggtgcgacca
     6061 ccagcgtggc gccagtgagc aaggccatcg acacgtccca gaaggcgccg tcgaaactcg
     6121 gcgaggaaaa gagcagcaac cggctggacg gcccgatccc caggtcccgc gcatggctgc
     6181 ccaccaggct ggcgatgccg tggtgggtga ggaccactcc tttgggagta ccggtggaac
     6241 ccgaggtgta gatgacatag gccggatgcc gggtccggag cggggcgccg cgttcgtcgt
     6301 ccgccacatc cgccgcggag cagtcggcca gggtccgtac gacggccggg tcgtccagca
     6361 ccaccgtgcg ggaggccgcc tcggccggca gctcgggctc gatgtcactc ctggtcagca
     6421 ccagcatggg agcggcgtcg gcgagcatga acgccagccg ctgcggagga tagtccggat
     6481 ccatcgggaa gtagccggcg cccgatttca gtacggccgc cacggccacc acgaagtcgg
     6541 tcgagcgcgg cagggcgaga ccgaccaggc tctccgggcc ggcgccacgt gcgatgagca
     6601 acctggcgag gcggttggcc cgccggttca gttcggcgta actcagccgc tcgctcgcgg
     6661 agttgatcgc ggtggattcg ggggcggcgt cgacacgggc ttcgaagagc cgtccccata
     6721 ggccgggggt gaactcgggg ccggcctggg ccccggcggg cgaggccgtg gtgcggcttc
     6781 gccccggcgg cagcatggac atcgagtgga cctcacagat gatgggatcg gacgggctgg
     6841 ccctgggagt cactgcagtg ggaggtcctg gacgcggaga tcgggatcct tcaacaacag
     6901 ggacagcacg acttcgtact gctgggcgag ccggacgacc gtgtcgtcgc gcagcagccc
     6961 gctctggtac tggatgtggc tgcgcagcgt cccgccgtcc gcggcggagg ccagatgctc
     7021 cacggtccac agcaccggat agcgggcgga ttcgctcgcc ggccgtgggc cgggactgat
     7081 ggtgaggccc ggcaggtcgg ccggcggagc tgcgaccgtg cgcaggacga gtgacacctg
     7141 gggcggtggc acgtcggcca ggcgctcgaa gagcaggtcc tggtgggcat aggcaccgag
     7201 atcggtcacg cggacccggt ccagcagttc gcggaaggtg gggttgcccg acgtgtcggt
     7261 gcgcagcgcc aaggtgttgg cgaagaggcc caccagcggt tcgaactggg tgtcggtccg
     7321 gccggccacc gcggtcacga cggtgacgtc ccctcctgct cccctgcggg cgagcagtgc
     7381 gacgagcgcg gcgtgcagga tcatgaagac ggtgacaccg tgctcacggg ccgcggctgt
     7441 cagcacccgg tggccgccga cttcgagcgg aagatcgagg gacctgccgg caaagtcctg
     7501 ctgggccggc gccgggctgt cggtctccag gaccggcctg tcgtcggcac cgtgcagcgt
     7561 cttcctccag tactccgcct ggcgcagcgc gacgtcgctc gggtcgtccg tggcgccgag
     7621 cagccggcgc tgccaggcga cgtagtcgag gtagccgaag gacagcggct cccactgtgg
     7681 tgcgcgcccc tcggtccggg cgcggtaggc gcggaccagg tcctccagca gggggccgaa
     7741 ggaccagccg tcggcggcga tgtgatgcat gaccagcagc agtacggact cgtccgggcc
     7801 gagcgtgaac agtacggccc gcagcgggat ctcggtctcg aggtcgaagt ggcggcgggc
     7861 ggcgtgcgcg agatcctcgg acagccgctc gggcgtggtc ctggtctccg tccatgggat
     7921 gtcgtccgcg gtggcttccg tgatcaccgc acacggaccg ctgccgtcgt cctggacgag
     7981 cgtgcgcagc ggaacgtgcc gggtgacgac atcggcgagg gcggcgcgca gtgcctcggc
     8041 gtcgacggca ccggtcagcc gctgcgacag cggcacgttg aacatgtcgc gacacaggct
     8101 tcggcggtac tcgtgccaca tctgcatctg ctgggccgac aacggcgccg tgctgccgga
     8161 ggcgtactcg ctcggcacgg gcagcggcct ggcctcgtcc cccgcgtcga agcgggcggc
     8221 gagcgcgccg acggtgggcg actcgaacag ccacgacagc ggcatctcgg tgttcaggcg
     8281 ccgccggacc tcggcggcga gtcgggtggc cagcagggag ttgccgccga cggcgaagaa
     8341 gtcgctgtcg gctgtgacgt cggctgtcgc gagtacgtcg gcgaagatcg ccgccagtac
     8401 ctcctcgcgg gcggtcctgg gcggacgtcc cgaggcatgg gcggcgcgcc gcggccgggg
     8461 cagggcgccg cggtcgagct ttccgttcac cgtgaccggc agcctgtcga gcgggacgaa
     8521 gacctccggg accatgaagg ccggcagctt cgccgcgacc tgcccgggaa gagaggccat
     8581 cgtctgggag tcggggcggg cgaacgccgg cctgttggtg aaccgggccg gggagaaacc
     8641 gtccggctcc gcgtcggtcc ggggggcggg acgcggcacg agcgctccgg cgcgtgtgaa
     8701 ggaagcgtcg atcagggcgt cgtcctcgga cgaccaggtg cagtcgaccc ggtagcccag
     8761 ttccgcgccc agccggcgca ggtcctccgg tgccacgccc gccggagcct gccccaggga
     8821 cagcacctcg tgcagggggc gccggtcgaa cagcgcgagt gtcgcggcat gctcgccggc
     8881 cacccggccg ttggggatcc cggtgacgca caaccgctcc ggtttcccac gacgcagccg
     8941 atcggcgacg tcggccaggc tcgccatctc gccgtcccac cgcagtcgca cgaccggccc
     9001 cgcgtcgtcc gtgggcccgg tgtcatcggc aggcccggca tgcttgcgca gcaccacctc
     9061 gtagcgatag cggctgagtt cgttgtcgta cccgccccgt ttgagcgtgc acgactccag
     9121 cgtcatgccg ggcagcgcgc cgacggccgt cgtgaagaac tccgggtcca cgagcagttc
     9181 cttctcctgc gccatggccc ggtcgatcgc cgcgcagacc gtctgcggag tgtcggtgtg
     9241 cgtggccgcc gccagcagcc ccccggcgtg gaaggtgcgc agcagacgaa ggttacggac
     9301 gtcgccgagg aacaccgcgc ccccgggtac caggagccgg gacacctcgc gcagtaggtc
     9361 gaacaggtaa tcgcctgagg gaaagtactg gatcacggag ttgagcacga cggtgtcgaa
     9421 gccgccgctg ggcagactcc ccagctcatg ggcggagagc tgatgcagga cgacccggtc
     9481 cgcgaggccg gggcgctcgg cgacctgccc gcgcagccgc tcgatcaggg ccccggagat
     9541 gtcggtgccc cagtagcttt cgcagtcacc cgccagctgc gagagcagca gaccggaacc
     9601 gcagccgatc tccagtacgc ggcgcggagc cagttcgcgg atctgccgca cggtctgctc
     9661 acgccattcg cgcatcccct cgatcggccg cccgccataa ctgctcaccc agccggagaa
     9721 gtcctcgccg aagtcggcgg tgtcggctcg gccgtacaga tcgtcgtaga gccgtcgcca
     9781 ggcatcgagt tgaccgtccg gttcctcgcc ggccgcctcg tcggcggccg cgttctcggg
     9841 tatgacgtag gcggcgaggt atggctctcc gggccggtcc tcacgcagga cgacggcggc
     9901 ctgccggacc ccgcggcacc cggcgatgac ggattcgatc tcgcccggct cgatacggaa
     9961 gccgcgtacc ttgacctggt cgtccgccct gccgacgaac tccaggtctc ctgaacgggt
    10021 ccagcggccg aggtcaccgc tgcggtacat acggctgccg gccgggccga aggggtccgc
    10081 cacgaaccgc tgcgcggtca gacccggccg ctcgaggtac ccgcgtgcca ggctgtgccc
    10141 cgcgatgtag atctcgccga ccgctcccgg cacaaccggt gcgaggcggt cgtcgaggac
    10201 atggatccgg gtgccgtcca ccgcccggcc gaccggcggc gccacgtcgt cggccagcgg
    10261 atcgctcatg gtggcgcaga cggtggactc cgtcgggccg taggcgttca ccatcgtccg
    10321 gtgcgggcgc cagcgctgca cgagagccgc cgggcacgct tcgcccgcga cgaccagcgt
    10381 cacgctcgga ggcagcatgt cggggcccag cgcacccgcg accgagggcg ggagagtgac
    10441 atgagtgact ccgtggtccg cgatcaacgc ggccagttcg gcgtcgggca gcagccgccc
    10501 cggcctgccg accacgagcg cggccccggc cagcagcgcc atcgacatct cccagaaact
    10561 ggcgtcgaaa ctcggggacg agaaggcgag cacgcgtgag gcgccggtga cggcgaggcg
    10621 acgacgctgg gtcgcgatca ggctcgcgac gccttggtgg gtgacgacga ctcccttggg
    10681 gatccccgtg gagccggagg tgtagatgat gtaggcggga ctcgcggggc gcagtggctc
    10741 caaacgttcc ccgtcctcca tgtcgtggtc cggcagacgg cgcagtacgt cctcggtggc
    10801 ctcgtcgtcc agtaccacga ggctgccggt gggcagctgg cccagaaggt cgccccggac
    10861 gtccgacgtc gtcaccagca ccacgggtgc tgcgtcccgg gccatgaagg acagtcgctc
    10921 cacggggtag ttcggatcca gcggcaggta cgcggccccg cacttgagca cggccgtcgc
    10981 gcacaggaag aagtccgcgg acctgcccag caccagcccg accgaccgct ccggcccggc
    11041 gccgaggtac ttcagccacc gggcgagccg gttcgcacgg gcattgaact gcgcgtacgt
    11101 gagcgccgtg tccccggcga cgagcgcgat ggcgtcaggt gtgtcggcca cccgcgcttc
    11161 gaggagactc ggccacgtcg tggcgagcgc tccctccggg agatcttcac cggtcaggtg
    11221 cgacacaggt atccgttcct ctctgtcgtc gagccgcccg tgggcgcgct caagccgatg
    11281 gcatggaaag cggaagcagg ggaggggaaa gacgtcgggc ctacgtgggg ccgagtggcg
    11341 ccaggagtgg tgagcgacga cggttcgggg ggccacgggg tacgggtgcc ggcttctcct
    11401 acgagaaccc gagccaccgc gtgcggccga cgggccgccg gatcgagaag cggttgcagg
    11461 agaaccgttc tcagaatgtc ttgtccgtcc cgatgaagca ggtgtcgtag caccgggaat
    11521 ccccctgtga atggttctcg cacgttggaa cataagcatc atggggttgt ttccgcggcg
    11581 cagtcttgtc ggtcagtgac cgcgtcgttg cctctggacg ccaggcttcc gtttgcagcg
    11641 ggagctactg cgaggaggcc acgtgccgac gatccagcgg ggtcgggcaa cggtgaggtg
    11701 gtgatccgcg cccggggtcc tgcagccccc gccacctcgc aaaatttcga caaacaaatt
    11761 cgacacagga agaccagact tccgcgaccg gaggaaagcg cagggagctg cctgtgactt
    11821 cccgcatcgg cagcgctcgc gctcgacgac tccgtccgtc cggcgggccg tcgcctcagt
    11881 caaccacccc ggcgtagcga gtgagtgcag ttgagcggat agctggtgag gtaaacccaa
    11941 cgggcgagtt cgatgaacgc acgtacggct gcgccgacaa tcccgcaggt ggcttgcgca
    12001 ccgcccgcca agacaatgct cctgtgtgcg caccctcagg agccaacaca caactccggt
    12061 caatcagtag gtacttgact ggactgccac ccgcagggca ctgtcaataa gcgggagcgc
    12121 tcccacagcg ctctcttgta cagcgcagca cctcctgatg agcagtgacg gactcgcacg
    12181 gactcagtaa gcgaagacgc gcacggcccc ttccccttac ggccgttcgt ggcctcgtga
    12241 tgagtgagga aaacctgatg gacaaatttg cctcggacag acctggaaac ccgatcgcgg
    12301 cgacggagtt tctctctccg cactgtttcc ggaggcgctg gccacggcat ggagaaacgg
    12361 ggcgcgaccg ttacggccac cctggcccgg gcggcggcat gccgtgcgag cgaggctcgc
    12421 tcgggcgtcg ccacggactc cggcgcagga gcgtttatgc ggtgcgatgc agtgacccgg
    12481 gtgactgcct gacgccagcc ggcggagacg gctggccaca ggcctgtcag atcgcacctc
    12541 ccctcggtcg acgcagcggg tgagcaagtc acccaacgtg gatccgaggg tccacgcacc
    12601 cacgatggag acgtccgcag cggaatgtca gcacacctga cccgtctgcg gcgcgcgagg
    12661 agcatcgatc gcacccgcgg gttgtgacca ggattctccc gcctccggcg ccagacccga
    12721 ttgacctggt agttgaaatt tcaatcaaac taagcgggtg aacgactggg ttcgttcctt
    12781 gcggaggatc tcgccgtggc ctgttctgaa ctgtttgtcg cgctcggagc cgagaagggg
    12841 gaagcatctt gcttcactcg atttccggcc gacgcgccga gcgcaaggta ctgccttttg
    12901 tcgagctcag gcatgcagat aaaatctttc aaggccggcg gggtcaaggt gacgatcata
    12961 gattccggtc cagccgtcat cgagttcgag gcaatcaact cggaggcggc cttgacgccg
    13021 cagagaacag tcatatgcgt actgtcagga atggcgttca tcgctggtac cggaaacggt
    13081 acggagatcg acgcggggac gctggttatg acggacggcg acgttccctt ttcgatgaat
    13141 gtgcccgttg cttcgcgact cctcgtactg cgtttcgccg acgaagcgaa ggatggactc
    13201 ccggtgtcgc ctcgggggac ttttatcgtg acggatgctg ccaagggtcc cggatccgga
    13261 tttctttttt cgttcttgaa taccctggct gtggagatga tgaaaaccga tgggattctg
    13321 tcctcgtata tggaggaggt cgtgcgcatc ctggcgatct ccgcgacgcg aatcgcatat
    13381 gccgagctcg gaaagcatta ctctggggga tgcgatccac ttctgatcgc ggttcaggag
    13441 tcgatcgacc ggcagttggc cgaccccgag atcagcccgg cgaccctcgc ggccgaacac
    13501 aacatatcgg tgcgtcagtt acatcgagtt ttcggaccga tcggggaaag cgtcatgagc
    13561 tatgtcaaac gccgtcgcct ggagcgtttc gcatgcgatc tgagggatcc gagcctgggg
    13621 caccggaaga tcaatgagct ggcggcggac tgggggatgc tggatgccgc gatgctgagc
    13681 agacacttcc gctgcgccta cggaatgtcg ccccgcgatt accggaagca gcactgtttc
    13741 acctgaaacg gcgagggcat gacggcggca gggacgacgt gtcgcccacg gttcggcacg
    13801 gggttcccgg cgccaccccg gcccgagaaa ggaccagggc cccgaaacgt ggtcgtggac
    13861 gagccgagtc agcacggtcc cggcacggga ggcctgcccc cgcaccatgc agctcagacg
    13921 ccaccacacg acacacctcg gtcactccac cgggccgaag gggagcgtcc tggtcaccgg
    13981 agtgccgacg ccgcacctcc tcgcgtgcgc tcttcggtcg cccacccggg acgtgcccgc
    14041 actgcgcgaa gcatcggaca ccgtggacgc ctccaccggc acgcacgcaa cttacgagca
    14101 ctcctggcca ggtgatgtga cttgcacctc gggctgaagc cggagggttc ccgccttctc
    14161 gatcgttgct gtgccactac gcggcccggg gctaggcggc acggatcgat ggccctgggc
    14221 acagccgtca tgcagctcat gcactgccga ccgcctgcgg gccggtcgcg aactcccgcc
    14281 acatcacaca gccttcggtg tcccacgttg cggggctgcg cggtcagtag ggcgtaactg
    14341 cgactcggtc aggggatccc catggatccg catctcgact gctacggcaa ctccctcgcg
    14401 gcctggagca ggtctgggag gtcggtgtga accggccgat cctgaccagg gtgcggccgt
    14461 accgttccgc tttgtactcc agcatgctga ggaacgatgg ccacccggcg tcgtgcacgg
    14521 acttggtcag cttcgtgcgg gccagtcccg ccaccgacag gtcctccacg gcgatccctt
    14581 ggtcatcacc cggcagccgg ccggcgccta ccaggtgggc cggttcggcg gagccggagg
    14641 gcctggcccg gccggataca cacggtgagt gccttcggtg ccaggtctca ggccggaagg
    14701 ttccggcggt cgcgtccgga acacctcgtc cgcgaccgcc ggcctgtgca gggcgaccag
    14761 cggcgacttc cccggcggcg ggccgggcag aagggcggaa cgagccacga cggcacggac
    14821 caactcgacc caggagagcc cggtctgcgg gtcggccggg gaaagtgcgg ccggactgcg
    14881 gcttgcgtgt tcccaggctg agccggtcca tcgacatccg gcgtctcaga cgctacgtca
    14941 cccgtgagat atacggtcag atgcaaccgc caccttcctc gccgcctcgt cttctgccgc
    15001 ctgccgcaac atcggggcat cctgaacgtt catctcgctt atggaatgcg gcagttcatc
    15061 gcccggcagg actggccgac ccgctaccgg ctggtctcct acgcacccgg cctcaacccg
    15121 gcggaaggct tctggtcgcc gctgcggtcc cgcaccgctt tcaccactct ccgagcacct
    15181 cagccggacc atcgaaacgg aatgaggaaa tctggtatgt ttcccactca tcgacggatg
    15241 cctcgccgga accggtccgt ccctcacgcc aacgacctca caagctcagt cgctgtcagg
    15301 acgagggaaa acctccaatt ccctcccggc tttaccggga tatgacaagg cgcctcgtgg
    15361 tgcggcagct ttcgtcggca cctcgcgcca tgcgcaggtc ccctgtccgc gaaggtatcg
    15421 aaaggtgcat agcggaactg gcatccaaca gctaaggatc agtcaccgat cgacaagatt
    15481 tcgtcgggga tgcctatcca tgatgaaggt gtgccggcgc acgatcttca agagagagga
    15541 attccggtgc cacggcgcct ccgtcaccag gacaggcaac acatgtgagc gtggttctcc
    15601 tgtgggccgc ttcttgatcc agcagccccg ttgctcgcac gcagtagctc aggtcctcgt
    15661 cggagaagcc gatctccgcg ccgaacggca cctgcgaatc accgccgctc gccacaggat
    15721 tcctccgctc cgtggccggg ctcgccccgt cgccggagat cccgcccggc gatgccgcgc
    15781 cgcccgccct gtcaacacgt atgcgccgcg actgacaacc acgggatcga gggctcgcct
    15841 cccatcccgg aattcctgcc gcgatccccg gctccgcatc ccttttcgac taccccaagg
    15901 aagcccctgt gaccgtcccc tcgccgctcg ccgacccgtc catcgtgccc gacccctacc
    15961 ctgtctacgc cgacctggcc cagcgccgcc ccgtccactg ggtcgagcgc ctgaacgcct
    16021 gggcggtctt gacgtacgcc gactgcgccg ccgggctgaa ggatccccgg ctcaccgccg
    16081 accgggggac ggaagtgctg gccgcgaagt tccccggaca gccgctgccg ccggacaaca
    16141 tcttccaccg ctggaccaag aacgtggtga tgtacacgga cccgccgctc cacgacgcgc
    16201 tacgccggtc cgtccgcgca ggcttcaccc gtgccgcgca ccagcactac gaccaagtcc
    16261 tccagaaggt cgcgcacgac ctggtcgctt ccatcccggc cggtgccacc gagatcgacg
    16321 ccgtccccgc cctggctgcc gaactccccg tacgctccgc cgtgcacgcc ttcggggtcc
    16381 ccgaggagga cctcggattc ctcatcccgc gcgtgaatac gatcatgacg taccactccg
    16441 gtccgaagga tcagccggtg acgcaggaga taatcctgga aaagctcacc gacctgcaca
    16501 cgtacgcctc cgaactcctc cagggcatgc ggggcaaggt cctgccggac accgtcatcg
    16561 cccgcctggc agccgcccag gacggcctga ccgagaccac gccggaacag accgtgcacc
    16621 agctggcgct ggtgttcatc gcgttgttcg cgcccacgac gccgggctct ctcagcagcg
    16681 gcacgctcgc gttcgcccgc aacccgcggc aggtcgaacg cttcctggcg gaccaggcgt
    16741 gcgtggacaa cacggcgaac gaggtcctcc gctacaacgc ctcgaaccag ttcacctggc
    16801 gcgtcgcggc caaggacgtc gagatgggcg gcgtacggat cgaggccggg cagactctcg
    16861 ccctgttcct gggctcggcc aaccgggacg ccaacatgtt cgagcgaccg aacgacttcg
    16921 acctcgaccg tcccaacagc gctcggcacc tgtcgttcgg ccaaggggtg cacgcctgtc
    16981 tcgccgcgca gctcatctcc ctgcagctga agtggttcta cgtcgccctg ctgaaccgct
    17041 tcccgggcat ccggacggcg ggcgagccga tctggaacga gaacctcgaa ttccgctccc
    17101 ttcgctccct gccgctcagc ctccgctgac gaggtcagcg ctctactccc ctgcgaggaa
    17161 tcgtgacctc cgaagtcgct ctgggccctt ccttgcccgc cccgtccccg acagcgtgcc
    17221 cggcactggg gcccgattcg tcccttggcc cggtcccgtc ggcggaaccg gcgacgccgc
    17281 agtcctgcgg cgtcgccgat ccaaatgagg ctgaggagtt cctgcgccag ttccacgcgg
    17341 agcagtccga tcagcccgtc ccgctcgccc ggcgcctgga gcaggtccgc gccgccatcg
    17401 acgccacggg cacctaccgg cacaccaccg ccgagctcgt gtacggtgcc cgcgtcgcgt
    17461 ggcgcaactc cagtcgctgc atcggccgcc tgtactggaa cagcctgcgc gtcctggacc
    17521 gccgggacgc cacagccccc gatgagatcc accggcactt gtgcacgcac ctgcgccagg
    17581 cgaccaacgg cgggcgcatc aggccggtga tttcggtctt cgccccggac tcccccggcc
    17641 ggcccggccc gcaggtgtgg aacgagcagc tcatccggta cgccggctac cgccgcgacg
    17701 acggcaccgt gctcggtgac ccgcgcaccg ccgacctcac cgaggccatc ctccgcctcg
    17761 gctggcaggg ctgcccccaa gggccgttcg acgtcctgcc cctggtcatc gacacccccg
    17821 acgacaaacc ccggttcttc gagctgccgc gggagctggt cttggaggtc cctatcaccc
    17881 accccgacgt cccacgcctg gccgaactgg gcctgcgctg gcacgccgta cccgtcatct
    17941 ccaacatgcg cctacgcatc ggcgggatgg actacccgct cgccccgttc aacggctggt
    18001 acatgggcac ggagatcggc gcccgcaacc tcgtcgacga ggaccgctac aacatgctcc
    18061 ccgccgtcgc cgcctgcctc cagctggaca ccaccagcga gtcaaccctg tggcgcgacc
    18121 gcgccctggt cgagctcaac gtcgccgtcc tgcactcctt cgaggccgca ggtgtccgga
    18181 tcagcgacca ccacgaggag tcccggcgct tcctcgccca cctggccaag gaggaacgcc
    18241 agggccgcac cgtatccgca gactggagct ggatcgtccc cccgctctcc ggcggcatca
    18301 cccccgtgtt ccaccgttac tacgacaacg tcgaccagcg ccccaacttc tacccccacc
    18361 agtgaagtga tgaggcgtct acaaccccgc cccgcagcat ctgctcgacg gccgccagtg
    18421 ccggcggctg tcgaactcct ccaggaagac gaggtgggaa tggcc
//
