BGC0002090: undecylprodigiosin biosynthetic gene cluster from Streptomyces griseoaurantiacus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 255,172 - 291,481 nt. (total: 36,310 nt).
This entry is originally from NCBI GenBank JACERG010000004.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002090
Short description undecylprodigiosin biosynthetic gene cluster from Streptomyces griseoaurantiacus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type I)
  • NRPS (Type I)
Loci
JACERG010000004.1
255172 - 291481
via
Compounds
  • undecylprodigiosin
  • metacycloprodigiosin
Species Streptomyces griseoaurantiacus [taxonomy]
References
Chemical products information
undecylprodigiosin Evidence: NMR, Mass spectrometry
Copy SMILES
Chemical database entries
PubCHEM
ChEMBL
ChemSpider
NPAtlas
ChemSpider
metacycloprodigiosin Evidence: NMR, Mass spectrometry
Copy SMILES
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • H1X69_07150
  • MBA5221201.1
 255172 - 257463 (+) ADP-ribosylglycohydrolase family protein
    copy AA seq
    copy Nt seq
    • H1X69_07155
    • MBA5221202.1
    		 257569 - 257790 (-) hypothetical protein
      copy AA seq
      copy Nt seq
      • H1X69_07160
      • MBA5221203.1
      		 257874 - 258095 (-) hypothetical protein
        copy AA seq
        copy Nt seq
        • H1X69_07165
        • MBA5221204.1
        		 258268 - 259248 (+) AfsR/SARP family transcriptional regulator
        • Regulation
        copy AA seq
        copy Nt seq
        • H1X69_07170
        • MBA5221205.1
        		 259248 - 262409 (+) polyketide synthase
        • Scaffold biosynthesis
        copy AA seq
        copy Nt seq
        • H1X69_07175
        • MBA5221206.1
        		 262406 - 263782 (+) acyl-CoA dehydrogenase family protein
        • Precursor biosynthesis
        copy AA seq
        copy Nt seq
        • H1X69_07180
        • MBA5221207.1
        		 263779 - 264129 (+) RedY protein
          copy AA seq
          copy Nt seq
          • H1X69_07185
          • MBA5221208.1
          		 264214 - 264840 (-) response regulator transcription factor
          • Regulation
          copy AA seq
          copy Nt seq
          • H1X69_07190
          • MBA5221209.1
          		 265254 - 266642 (-) RedV protein
            copy AA seq
            copy Nt seq
            • H1X69_07195
            • MBA5221210.1
            		 266760 - 267599 (-) 4'-phosphopantetheinyl transferase superfamily protein
            • Activation / processing
            copy AA seq
            copy Nt seq
            • H1X69_07200
            • MBA5221211.1
            		 267601 - 268491 (-) hypothetical protein
              copy AA seq
              copy Nt seq
              • H1X69_07205
              • MBA5221212.1
              		 268538 - 268981 (-) hypothetical protein
                copy AA seq
                copy Nt seq
                • H1X69_07210
                • MBA5221213.1
                		 269049 - 270293 (-) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
                • Scaffold biosynthesis
                copy AA seq
                copy Nt seq
                • H1X69_07215
                • MBA5221214.1
                		 270290 - 270538 (-) acyl carrier protein
                • Scaffold biosynthesis
                copy AA seq
                copy Nt seq
                • H1X69_07220
                • MBA5221215.1
                		 270944 - 271972 (+) ketoacyl-ACP synthase III
                • Scaffold biosynthesis
                copy AA seq
                copy Nt seq
                • H1X69_07225
                • MBA5221216.1
                		 272128 - 272388 (+) acyl carrier protein
                  copy AA seq
                  copy Nt seq
                  • H1X69_07230
                  • MBA5221217.1
                  		 272385 - 274307 (+) aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
                  • Scaffold biosynthesis
                  copy AA seq
                  copy Nt seq
                  • H1X69_07235
                  • MBA5221218.1
                  		 274321 - 276135 (+) AMP-binding protein
                  • Precursor biosynthesis
                  copy AA seq
                  copy Nt seq
                  • H1X69_07240
                  • MBA5221219.1
                  		 276147 - 284216 (+) aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
                  • Scaffold biosynthesis
                  copy AA seq
                  copy Nt seq
                  • H1X69_07245
                  • MBA5221220.1
                  		 284296 - 285261 (+) thioesterase
                  • Scaffold biosynthesis
                  copy AA seq
                  copy Nt seq
                  • H1X69_07250
                  • MBA5221221.1
                  		 285249 - 286421 (+) methyltransferase domain-containing protein
                  • Tailoring
                  copy AA seq
                  copy Nt seq
                  • H1X69_07255
                  • MBA5221222.1
                  		 286451 - 289267 (+) phosphoenolpyruvate-utilizing enzyme
                  • Scaffold biosynthesis
                  copy AA seq
                  copy Nt seq
                  • H1X69_07260
                  • MBA5221223.1
                  		 289538 - 291481 (+) acyltransferase family protein
                  • Tailoring
                  copy AA seq
                  copy Nt seq
                  Biosynthesis information

                  Biosynthetic modules

                  Name
                  Unk01
                  Type
                  nrps-type1
                  Genes
                  H1X69_07235
                  Substrates
                  proline (evidence: Structure-based inference, Homology)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk02
                  Type
                  nrps-type1
                  Genes
                  H1X69_07240
                  Substrates
                  pyrrole-2-carboxylic acid (evidence: Structure-based inference, Homology)
                  Integrated Monomers
                  Domains
                  adenylation
                  Annotation changelog

                  Entry version: 2

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-10-07
                  Update chemical activity to schema version 2.11
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 1

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-09-15
                  Submitted
                  • (ID: HSOJFFPY5IUT4HBQLSN7DGJX)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  2022-09-15
                  Added version to NCBI accession
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  2022-09-15
                  Added NRP substrate specificities
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  Detailed domain annotation
                  Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                  A domain glossary is available here, and an explanation of the visualisation is available here.
                  Selected features only
                  Show module domains
                  Similar known gene clusters from MIBiG 4.0
                  Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                  Click on reference genes to show details of similarities to genes within the current region.
                  Click on an accession to open that entry in the MiBIG database.