BGC0002090: undecylprodigiosin biosynthetic gene cluster from Streptomyces griseoaurantiacus
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Location: 255,172 - 291,481 nt. (total: 36,310 nt).
This entry is originally from NCBI GenBank JACERG010000004.1.

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core biosynthetic genes
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Gene details
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General
Compounds
Genes
Polyketide
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002090
Short description undecylprodigiosin biosynthetic gene cluster from Streptomyces griseoaurantiacus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
  • NRP
Loci NCBI GenBank: JACERG010000004.1
Compounds
  • undecylprodigiosin
  • metacycloprodigiosin
Species Streptomyces griseoaurantiacus [taxonomy]
References
Chemical products information
undecylprodigiosin
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Chemical database entries
PubCHEM
ChEMBL
ChemSpider
NPAtlas
ChemSpider
metacycloprodigiosin
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Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • H1X69_07150
  • MBA5221201.1
 255172 - 257463 (+) ADP-ribosylglycohydrolase family protein
  • Unknown
Sequence-based prediction
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  • H1X69_07155
  • MBA5221202.1
 257569 - 257790 (-) hypothetical protein
  • Unknown
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  • H1X69_07160
  • MBA5221203.1
 257874 - 258095 (-) hypothetical protein
  • Unknown
Sequence-based prediction
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  • H1X69_07165
  • MBA5221204.1
 258268 - 259248 (+) AfsR/SARP family transcriptional regulator
  • Regulation
Sequence-based prediction
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  • H1X69_07170
  • MBA5221205.1
 259248 - 262409 (+) polyketide synthase
  • Scaffold biosynthesis
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  • H1X69_07175
  • MBA5221206.1
 262406 - 263782 (+) acyl-CoA dehydrogenase family protein
  • Precursor biosynthesis
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  • H1X69_07180
  • MBA5221207.1
 263779 - 264129 (+) RedY protein
  • Unknown
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  • H1X69_07185
  • MBA5221208.1
 264214 - 264840 (-) response regulator transcription factor
  • Regulation
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  • H1X69_07190
  • MBA5221209.1
 265254 - 266642 (-) RedV protein
  • Unknown
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  • H1X69_07195
  • MBA5221210.1
 266760 - 267599 (-) 4'-phosphopantetheinyl transferase superfamily protein
  • Activation / processing
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  • H1X69_07200
  • MBA5221211.1
 267601 - 268491 (-) hypothetical protein
  • Unknown
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  • H1X69_07205
  • MBA5221212.1
 268538 - 268981 (-) hypothetical protein
  • Unknown
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  • H1X69_07210
  • MBA5221213.1
 269049 - 270293 (-) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
  • Scaffold biosynthesis
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  • H1X69_07215
  • MBA5221214.1
 270290 - 270538 (-) acyl carrier protein
  • Scaffold biosynthesis
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  • H1X69_07220
  • MBA5221215.1
 270944 - 271972 (+) ketoacyl-ACP synthase III
  • Scaffold biosynthesis
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  • H1X69_07225
  • MBA5221216.1
 272128 - 272388 (+) acyl carrier protein
  • Unknown
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  • H1X69_07230
  • MBA5221217.1
 272385 - 274307 (+) aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
  • Scaffold biosynthesis
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  • H1X69_07235
  • MBA5221218.1
 274321 - 276135 (+) AMP-binding protein
  • Precursor biosynthesis
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  • H1X69_07240
  • MBA5221219.1
 276147 - 284216 (+) aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
  • Scaffold biosynthesis
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  • H1X69_07245
  • MBA5221220.1
 284296 - 285261 (+) thioesterase
  • Scaffold biosynthesis
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  • H1X69_07250
  • MBA5221221.1
 285249 - 286421 (+) methyltransferase domain-containing protein
  • Tailoring (Methylation)
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  • H1X69_07255
  • MBA5221222.1
 286451 - 289267 (+) phosphoenolpyruvate-utilizing enzyme
  • Scaffold biosynthesis
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  • H1X69_07260
  • MBA5221223.1
 289538 - 291481 (+) acyltransferase family protein
  • Tailoring (Oxidation)
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Polyketide-specific information
Subclass Unknown
Starter unit Malonyl-CoA
Cyclic? yes
Polyketide-synthases
Genes Properties Modules
H1X69_07245 Synthase subclass: Modular type I
Thioesterases:
  • H1X69_07245 (Type II)
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
H1X69_07235
Module ?
Specificity: proline
Evidence for specificity:
  • Structure-based inference
  • Homology
H1X69_07240
Module ?
Specificity: pyrrole-2-carboxylic acid
Evidence for specificity:
  • Structure-based inference
  • Homology
Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: HSOJFFPY5IUT4HBQLSN7DGJX, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
  • Added version to NCBI accession
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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