BGC0002091 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002091 (Yersinia ruckeri ATCC 29473)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	17,973	holomycin	NRPS:Type I	100%

BGC0002091 - Region 1 - NRPS

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Location: 1 - 17,973 nt. (total: 17,973 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 17,974
Label		BGC0002091

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002091	1.00	NRP	holomycin	Yersinia ruckeri ATCC 29473
BGC0002412	0.38	NRP	holomycin	Photobacterium galatheae
BGC0002410	0.25	NRP	frankobactin A1, frankobactin A2, frankobactin A3, frankobactin B1, frankobactin B2, frankobactin B3, frankobactin C1	Frankia sp. CH37
BGC0002476	0.24	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0000131	0.24	Polyketide	pyrrolomycin	Streptomyces sp. UC 11065
BGC0000894	0.23	Other	citrinin	Monascus aurantiacus
BGC0001778	0.23	Other	showdomycin	Streptomyces showdoensis
BGC0000347	0.23	NRP	equibactin	Streptococcus equi subsp. equi
BGC0002468	0.22	NRP	anguibactin	Vibrio anguillarum 775
BGC0002518	0.22	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002091	1.00	NRP	holomycin	Yersinia ruckeri ATCC 29473
BGC0002412	0.70	NRP	holomycin	Photobacterium galatheae
BGC0002410	0.58	NRP	frankobactin A1, frankobactin A2, frankobactin A3, frankobactin B1, frankobactin B2, frankobactin B3, frankobactin C1	Frankia sp. CH37
BGC0002476	0.57	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0000131	0.57	Polyketide	pyrrolomycin	Streptomyces sp. UC 11065
BGC0000894	0.56	Other	citrinin	Monascus aurantiacus
BGC0001778	0.56	Other	showdomycin	Streptomyces showdoensis
BGC0000347	0.56	NRP	equibactin	Streptococcus equi subsp. equi
BGC0002468	0.55	NRP	anguibactin	Vibrio anguillarum 775
BGC0002518	0.54	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 17973:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

yruck0001_11740

Search NORINE for peptide: strict or relaxed

AMP-binding (532..926): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code(s):: Cys DLYNLSLIWK (100% 8Å match)
Stachelhaus code match:: 100% (strong)