BGC0002091: holomycin biosynthetic gene cluster from Yersinia ruckeri ATCC 29473
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Location: 3,593 - 21,565 nt. (total: 17,973 nt).
This entry is originally from NCBI GenBank ACCC01000028.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002091
Short description holomycin biosynthetic gene cluster from Yersinia ruckeri ATCC 29473
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: ACCC01000028.1
Compounds
  • holomycin
Species Yersinia ruckeri ATCC 29473 [taxonomy]
References
Chemical products information
holomycin
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Chemical database entries
NPAtlas
PubCHEM
ChEBI
ChEMBL
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • yruck0001_11670
  • EEP98509.1
 3594 - 4163 (+) hypothetical protein
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  • yruck0001_11680
  • EEP98510.1
 4250 - 4795 (-) Lantibiotic biosynthesis protein, flavoprotein
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  • yruck0001_11690
  • EEP98511.1
 4857 - 5288 (-) Globin
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  • yruck0001_11700
  • EEP98512.1
 5369 - 6241 (-) Acetyltransferase
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  • yruck0001_11710
  • EEP98513.1
 6266 - 7396 (-) Acyl-CoA dehydrogenase fadE20
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  • yruck0001_11720
  • EEP98514.1
 7413 - 8144 (-) hypothetical protein
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  • yruck0001_11730
  • EEP98515.1
 8165 - 9772 (-) Glucose-methanol-choline oxidoreductase
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  • yruck0001_11740
  • EEP98516.1
 9781 - 13152 (-) Peptide synthetase
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  • yruck0001_11750
  • EEP98517.1
 13985 - 15346 (+) Transporter, major facilitator family
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  • yruck0001_11760
  • EEP98518.1
 15403 - 15951 (-) Transcriptional regulator, ArsR family/rhodanese-like domain protein
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  • yruck0001_11770
  • EEP98519.1
 16210 - 16716 (+) hypothetical protein
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  • yruck0001_11780
  • EEP98520.1
 16967 - 17218 (+) hypothetical protein
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  • yruck0001_11790
  • EEP98521.1
 17521 - 18375 (-) rRNA (Guanine-N1-)-methyltransferase
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  • yruck0001_11800
  • EEP98522.1
 18473 - 20182 (-) Peptidoglycan synthetase ftsI
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  • yruck0001_11810
  • EEP98523.1
 20394 - 21134 (+) hypothetical protein
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  • yruck0001_11820
  • EEP98524.1
 21243 - 21434 (+) Cold shock-like protein cspE
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  • yruck0001_11830
  • EEP98525.1
 21449 - 21565 (-) hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? no
Thioesterase genes
  • yruck0001_11720 (Unknown)
NRP-synthases
Gene Modules
yruck0001_11740
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: SJG3CBEHSM6A3I74YXLH6GLA, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Hidden contributor (ID: 3UOU7PODQJXIM6BEPUHHRRA5, no GDPR consent given).
  • Submitted
  • Added version to NCBI accession
  • Convert from RefSeq to Genbank
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
  • Changed chemical structures for compounds: holomycin.
Detailed domain annotation
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