BGC0002092: stechlisin B2 biosynthetic gene cluster from Pseudomonas sp.
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 77,514 nt. (total: 77,514 nt).
This entry is originally from NCBI GenBank MT080808.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002092
Short description stechlisin B2 biosynthetic gene cluster from Pseudomonas sp.
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP (Cyclic depsipeptide)
Loci NCBI GenBank: MT080808.1
Compounds
  • stechlisin B2
  • stechlisin C3
  • stechlisin D3
  • tensin
  • stechlisin E2
  • stechlisin F
Species Pseudomonas sp. [taxonomy]
References
Chemical products information
stechlisin B2
Copy SMILES
C65H112N12O12
Chemical database entries
NPAtlas
stechlisin C3
Copy SMILES
C66H114N12O20
Chemical database entries
NPAtlas
stechlisin D3
Copy SMILES
C67H116N12O20
Chemical database entries
NPAtlas
tensin
Copy SMILES
C67H116N12O20
Chemical database entries
NPAtlas
stechlisin E2
Copy SMILES
C68H118N12O20
Chemical database entries
NPAtlas
stechlisin F
Copy SMILES
C69H120N12O20
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QNL34621.1
  • luxR
 18718 - 19512 (-) LuxR
copy AA seq
copy Nt seq
  • QNL34616.1
  • steA
 20001 - 26411 (+) SteA
copy AA seq
copy Nt seq
  • QNL34617.1
  • steB
 26658 - 39674 (+) SteB
copy AA seq
copy Nt seq
  • QNL34618.1
  • steC
 39671 - 57514 (+) SteC
copy AA seq
copy Nt seq
  • QNL34619.1
  • macA
 57581 - 58729 (+) MacA
copy AA seq
copy Nt seq
  • QNL34620.1
  • macB2
 58732 - 60690 (+) MacB2
copy AA seq
copy Nt seq
NRP-specific information
Subclass Cyclic depsipeptide
Cyclic? yes
Release type
  • Macrolactonization
NRP-synthases
Gene Modules
steA
Module 1
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Starter
Module 2
Specificity: aspartic acid / glutamic acid
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
steB
Module 3
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module 4
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module 5
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module 6
Specificity: serine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
steC
Module 10
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 11
Specificity: glutamic acid
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 7
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Module 8
Specificity: glutamine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 9
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: 7JBBERLOMRODNNGUFOT34CPQ, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
  • Corrected NRP module activity
  • Added version to NCBI accession
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
  • Changed chemical structures for compounds: stechlisin E2, stechlisin B2, stechlisin C3, stechlisin F, stechlisin D3, tensin.
  • Added NPAtlas links to compounds: stechlisin E2, stechlisin B2, stechlisin C3, stechlisin D3.
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.