LOCUS       BGC0002093             41852 bp    DNA     linear   PLN 02-APR-2019
DEFINITION  Talaromyces variabilis HXQ-H-1 polyketide synthase-nonribosomal
            peptide synthetase (iccA), ring expansion P450 (iccC), short-chain
            dehydrogenase TIC 32 (iccH), epimerase (iccE), Diels-Alderase
            (iccD), cytochrome P450 (iccF), trans-enoyl reductase (iccB), and
            NADH-dependent flavin oxidoreductase (iccG) genes, complete cds.
ACCESSION   BGC0002093
VERSION     BGC0002093
KEYWORDS    .
SOURCE      Talaromyces variabilis
  ORGANISM  Talaromyces variabilis
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae;
            Talaromyces.
REFERENCE   1  (bases 1 to 41852)
  AUTHORS   Zhang,Z., Jamieson,C.S., Zhao,Y.-L., Li,D., Ohashi,M., Houk,K.N. and
            Tang,Y.
  TITLE     Enzyme-Catalyzed Inverse-Electron Demand Diels-Alder Reaction in the
            Biosynthesis of Antifungal Ilicicolin H
  JOURNAL   J. Am. Chem. Soc. (2019) In press
   PUBMED   30905148
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 41852)
  AUTHORS   Zhang,Z., Jamieson,C.S., Zhao,Y.-L., Ohashi,M., Houk,K.N. and
            Tang,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2019) Chemical and Biomolecular Engineering,
            University of California, Los Angeles, 420 Westwood Plaza, Los
            Angeles, CA 90095, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Abyss v. 1.5.2
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            ##antiSMASH-Data-START##
            Version               :: False
            Run date              :: 2025-08-15 20:57:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start           :: 0
            Orig. end             :: 41852
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..41852
                     /country="China: coast of Fujian Province"
                     /db_xref="taxon:28576"
                     /isolation_source="mangrove rhizosphere soil"
                     /mol_type="genomic DNA"
                     /organism="Talaromyces variabilis"
                     /strain="HXQ-H-1"
     region          1..41852
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     subregion       1..41852
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="PKS, NRPS"
                     /subregion_number="1"
                     /tool="antismash"
     cand_cluster    1..40470
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..40470
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[8375:20470](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(8376..20470)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..40470
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[8375:20470](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(8376..20470)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     mRNA            complement(join(<8376..16085,16133..>20470))
                     /gene="iccA"
                     /product="polyketide synthase-nonribosomal peptide
                     synthetase"
     gene            complement(<8376..>20470)
                     /gene="iccA"
     CDS             complement(join(8376..16085,16133..20470))
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (18-446). E-value:
                     1.5e-166. Score: 546.4. Matches aSDomain:
                     nrpspksdomains_iccA_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (559-878). E-value: 5.5e-88.
                     Score: 287.1. Matches aSDomain:
                     nrpspksdomains_iccA_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (953-1131). E-value: 3.5e-26.
                     Score: 84.5. Matches aSDomain:
                     nrpspksdomains_iccA_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1394-1612). E-value: 4e-83. Score:
                     270.9. Matches aSDomain: nrpspksdomains_iccA_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2119-2295). E-value: 5.2e-54.
                     Score: 174.9. Matches aSDomain:
                     nrpspksdomains_iccA_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2405-2485). E-value: 3.7e-10.
                     Score: 32.0. Matches aSDomain:
                     nrpspksdomains_iccA_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2597-2889). E-value:
                     5.1e-55. Score: 178.5. Matches aSDomain:
                     nrpspksdomains_iccA_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (3063-3459). E-value:
                     2.3e-85. Score: 278.6. Matches aSDomain:
                     nrpspksdomains_iccA_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (3580-3645). E-value:
                     2.3e-12. Score: 39.3. Matches aSDomain:
                     nrpspksdomains_iccA_PP-binding.1"
                     /NRPS_PKS="Domain: TD (3695-3923). E-value: 2.2e-47. Score:
                     153.2. Matches aSDomain: nrpspksdomains_iccA_TD.1"
                     /codon_start=1
                     /gene="iccA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /note="IccA; PKS-NRPS"
                     /product="polyketide synthase-nonribosomal peptide
                     synthetase"
                     /protein_id="QBQ83704.1"
                     /sec_met_domain="mod_KS (E-value: 1.1e-144, bitscore:
                     471.4, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 8.8e-147, bitscore:
                     478.4, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 2.1e-139, bitscore:
                     454.1, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.4e-73, bitscore:
                     236.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.2e-170, bitscore:
                     556.9, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 2.1e-167, bitscore:
                     546.4, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 5.7e-59, bitscore: 188.9,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 7.4e-89, bitscore: 287.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 7.6e-46, bitscore:
                     145.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 7.8e-48, bitscore:
                     152.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.8e-87, bitscore:
                     280.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3e-13, bitscore:
                     39.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 7.3e-22, bitscore:
                     66.7, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAANDSNNQTKPQLPEEPVAIVGSSCRFPGSSNSPSKLWDLLRQP
                     RDVLKEFDPDRLNLKRFYHPDGDTHGSTDVTNKSYLLEEDSRLFDASFFTINPAEAAGM
                     DPQQRILLETVYEAFESAGMTLEQLRGSLTAVHVGTMTNDYAGIQLRDLETIAKYNATG
                     TANSIVSNRISYVFDLKGPSETIDTACSSSLVALHHAARGLLNGDCETAVVAGVNLIYD
                     AASYIAESKLHMLSPDSQSRMWDKSANGYARGEGAAALLLKPLSRALRDGDHIEGVIRA
                     TGVNSDGQSPGITMPFAPTQAALIRQTYRRAGLDPVKDRPQYFECHGTGTPAGDPVEAR
                     AISEAFEPSADNPIYVGSIKTIIGHLEGCAGLAGVMKVILALKNRTIPPNMLFNELNPA
                     IAPFYGPLQIPKKAMPWPELPENTPIRASVNSFGFGGTNAHVIIESFESSTPSSDSEKC
                     EEGALGPLLFSAGSGASLLHTVQAYVQYLDQNPSVDLRDLSWLLQTRRSTHRVRTHFSG
                     TSSDAILESMIKFVNNNEKTPSTEVGHQPKLINPKEVPGILGVFTGQGAQWPQMGKELI
                     GKSPIFRRTLEDCDATLQALPSSDIPKWSLVKELMANASSSRVAEAAISQPLCTAVQLG
                     LVNMLKASGLNFDAVVGHSSGEIAATYASGIINLQAAIQIAYYRGFHAKLAKGEKGQQG
                     GMLAAGLTLDKAKQLCLREEFVGRLQVAASNAPQTVTLSGDLDAIEEVKKYLDEENVFA
                     RQLKVDTAYHSHHMKPCAEPYLKSLLACDIEVRKPTPGQCIWNSSVRGDTGLLKGDLSS
                     LKGPYWVANMVQTVLFSQAVESSIWHGGPWDLAIEVGPHPALKGPTEQTLKAVYGVVPL
                     YTGVLKRGASDVEAFSTAIGVTWSQLGPSFVDFAGYRKTFYESEPPTPKVIKDLPGYSW
                     DHDKVYWRESRISKRYRTGRDQTHELLGRRTPDDNEFELRWRNVLKLSEMPWLRGHEVL
                     EEVLLPGAAYVSIAVEASKHIATSKGKSIELLEVEDVDIQRPVVVPDNKEGVETLFTAR
                     LLPGSSSDKVLKALFSYYICNDQSTGTMVHTCSGRLSVHLGEAKEDVLPQRDPVPQNLV
                     NINTDRAYGMFKDIGLNYTGVFRSIKESSRTLQYSAATGIWPEGSLSDKYLVHPAMLDV
                     AFQTLFIARAHPASRLITSALLPSHIERIQVSPSVPILHARENSDEIKADFDCWVVHQT
                     ASSLTGDLNIYDKVSGKTFLQVEGLTTKMVGEQDASGDRPVFTKTVWGSDGSLGLDEPE
                     RDPVGDAEGLSLAEAAERMALFYMKRVVKEISPEERTKFQWYHQRMFEAFEQHLVNVGS
                     GSHPMLKSEWLSDDSSIMDGLDRIHPTSIDLKLLRACGENMPDVVREKTQLLEVMSKDD
                     MLNRFYMDNCAARINNDIAKVVKQISFKFPRANILEIGAGTGGTTWSILKDINDAYDSY
                     TFTDISSGFFPKAAEKFSDFAHKMIFKTLDVEKQPSEQGFAENSYDVIVAANVLHATRS
                     LETTLRNARSLLRPGGYLILMEITNPESLRTTFIFGGFSGWWLSEEPHRKLGPVVTAMD
                     WDTVLNDTGYSGADMVVHDLAEESKHLTSLIVSQAVDDDFLRLREPLSNLADMSAPTES
                     ILVIGGKKLLTSKMVNEINKLLPKSWKRHISSAGSIDDIDINELKPGTEVISLQELDDP
                     LFSTPMTAERMSTIQNLMMSAKTLLWVTTAGKSHAPRASMFHGIARIVPSELQHLQIQV
                     LGLEAGSTPAIATRHCVEAFLRLRGTSDTTREMLWAIEPEVEIMADGQVLIPRVVPDET
                     LNQTYNASRRVVTKTVDATDLAVEAVAGPTKMMLQTAELQAGERKTRIQVKYALHLPAM
                     DGKGIYVVYGQRQDDTSSFVLAVSKSNSSIVDVDSKHAVSVSDNCEPATLNVLATYLIA
                     RAIATLSKQAGSVLLSEPEESLAAIVATETAKQGTQAYFLSSKKVSPVEWIKVHANASK
                     RAIQKAVPHDVQLLIDCSGIEASGNAVMASMPLHCVERQLDAHLLFDALESTESKPESL
                     LEEAYQYATQLITQEQVQSECEVFPASDLPLTNMLSLVHKKYVTDWQQRDSLVVSVPPL
                     DLEGIFKADKTYLMVGAAGGLGLSICEWMIRNGAKNLIITSRKPQVDQNMIEEASRVGA
                     TVKVMAMDVSSKESVAEVVQQAQEIMPPIAGVCNAAMVLSDKMFLDMDVDQLNGTLAAK
                     VYGTEHLDAVFADAPLDFFIVLSSTATTIGNIGQANYHVANLFMTSLVAQRRARGLAGS
                     VIHIGYVADVGYVTRQDRERQLEQHFRNVRLMALSETDVHHAFAEAVRGGRPGNTVGSP
                     DIIMGLEPASVPLEPERQTLWLSNPCFGHLVPSTLQNDSSQTGGTGNGSSVRRQVEEAQ
                     TEDEAVDAVLDGFCAKLEAILQLREGSVKENVQRAVIDLGIDSLVAVEIRTWFLKELGA
                     EVPVVKILGGDTVLQICTTAAKKVMANAMKKKEEDAVAEEGGREAASKKEPAPAASAPT
                     PAPVAPSLLDVPARAFEPDSATISEVGDDSAFSNKGSSSSATGASSPKELSDSESVPDT
                     SKDQSHVRPETVRDERMSPAQARIWFLTKHLDDPSAYNMVFHYRVKGPLKTVRLRHALQ
                     VATGHHESLRTLFYSRLEDGQPMQGVMPASAYELKHVPGADEADLKKELALLKAREWDL
                     ENGRTFSVSVLSRAADEHDVVFGYHHIIMDVVGWYFFVRDLDRAYRMQPFDKKISGSYV
                     DYSVMQLSQKNTAAASDDLAFWQKEFSTVPDPIPLLPIAAVSARPTDSGRKVSHHEYLE
                     LDPAQNLAVKETCEKLRISPFHFHVAVLRALIGGYTNIDDMCIGVVDANRGDERFAQTV
                     GCFVNMLPVRVEAPSDATFADIARSASRKALMAFAHSSAPLDMILDAVKAPRSSETTPL
                     FQVAVNYRTGGVWDLPMGDCQMKLSLTDGKDAENPFDISLGIAETGKGCVIEMHCQKTL
                     YSSDATRTLLNTYLRLVDTFCKNTHVKLKDCVIHDQAKVSEALQIGKGPTTDFGWPSTL
                     SHRVLETCLKSPKNAAIQFKGELLSYEQLASRIHLVAAAIVRAGASKGSRVAVLCEPSA
                     DAIISMLATLHIGGVYIPMDVSLPTARHAAMMNGGQPTLLLSHAATKHRVEDLVNETGS
                     TISVLQVDTISSVEEKETVSCAAEPHNNAVLLFTSGSTGTPKGIMLSQANFVNHLALKT
                     DRLQLGQENVLQQSSMGFDMSLIQMFCALANGGCLVIAPSEMRRDPVELTNLVHNSQIS
                     LTIATPSEYLAWLRYGTASLKDHTIWRHACMGGEPVSRQLKTEFWRLDLANLQLTNCYG
                     PTEITAAATFETIRLDDQDDDNDRAQHAVGKALPNYSVRILDTAGRPQPVDHIGEICIG
                     GASVALGYLGLPEQTKAKFTVDPVSGERLYLTGDKGKLLSDGTLLCLGRLDGDTQIKHR
                     GLRIELQEVESALIQTANGLFSSAVVSARGSILVAHATISQSQAEPSESDLAKILSRLK
                     LPQYFIPATIGILPTMPTTANGKLDRKAIASLPLPQKVTGEEGPQEKMNIREGELRLLW
                     ERVLPDTATTTPLGPSSDFFLCGGNSMLLMKLQAAIKESIGIEISTRVLYQASTLREMA
                     LCVDEQREEQADALEQHFDWQAETSLPKWLLDQIEDLPKTTKQPPKPNGIDILMTGATS
                     FIGGRLLRSLVRSPSVRKVHCVAVLADEQDQLYQDEKVKCYTGSLLSSTLGLNNGERDQ
                     LARNVDVVIHAGSSGHCLNTYGSLRTPNLVSLQFLASLALPRSIPLLLLSSNRVPLLSG
                     NTALPPTSVAAFPPATDGREGYTATKWASEVFLEKLVGAVQKKAPRPWVASVHRPCVVV
                     SEHAPNSDALNAILRYSASMKCVPHLESATGYLDFASVESIVDSMAESAIEMATGNVTD
                     QPSIRFQHHSGGVKVPIGDFKVHMENVYGGNFEEVHLEEWMHRAAAAGLDPLITAYMEG
                     IIEAGAPIVFPYLGETV"
     aSDomain        complement(8655..9338)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccA_TD.1"
                     /evalue="2.20E-47"
                     /label="iccA_TD.1"
                     /locus_tag="iccA"
                     /protein_end="3923"
                     /protein_start="3695"
                     /score="153.2"
                     /tool="antismash"
                     /translation="ILMTGATSFIGGRLLRSLVRSPSVRKVHCVAVLADEQDQLYQDEK
                     VKCYTGSLLSSTLGLNNGERDQLARNVDVVIHAGSSGHCLNTYGSLRTPNLVSLQFLAS
                     LALPRSIPLLLLSSNRVPLLSGNTALPPTSVAAFPPATDGREGYTATKWASEVFLEKLV
                     GAVQKKAPRPWVASVHRPCVVVSEHAPNSDALNAILRYSASMKCVPHLESATGYLDFAS
                     VESIVD"
     aSModule        complement(8655..12632)
                     /complete
                     /domains="nrpspksdomains_iccA_Condensation_LCL.1"
                     /domains="nrpspksdomains_iccA_AMP-binding.1"
                     /domains="nrpspksdomains_iccA_PP-binding.1"
                     /domains="nrpspksdomains_iccA_TD.1"
                     /final_module
                     /locus_tags="iccA"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(9489..9683)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccA_PP-binding.1"
                     /evalue="2.30E-12"
                     /label="iccA_PP-binding.1"
                     /locus_tag="iccA"
                     /protein_end="3645"
                     /protein_start="3580"
                     /score="39.3"
                     /tool="antismash"
                     /translation="LRLLWERVLPDTATTTPLGPSSDFFLCGGNSMLLMKLQAAIKESI
                     GIEISTRVLYQASTLREMAL"
     CDS_motif       complement(9993..10046)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0015"
                     /evalue="2.10E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="iccA"
                     /protein_end="3477"
                     /protein_start="3459"
                     /score="17.2"
                     /tool="antismash"
                     /translation="GDTQIKHRGLRIELQEVE"
     aSDomain        complement(10047..11234)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccA_AMP-binding.1"
                     /evalue="2.30E-85"
                     /label="iccA_AMP-binding.1"
                     /locus_tag="iccA"
                     /protein_end="3459"
                     /protein_start="3063"
                     /score="278.6"
                     /tool="antismash"
                     /translation="KSPKNAAIQFKGELLSYEQLASRIHLVAAAIVRAGASKGSRVAVL
                     CEPSADAIISMLATLHIGGVYIPMDVSLPTARHAAMMNGGQPTLLLSHAATKHRVEDLV
                     NETGSTISVLQVDTISSVEEKETVSCAAEPHNNAVLLFTSGSTGTPKGIMLSQANFVNH
                     LALKTDRLQLGQENVLQQSSMGFDMSLIQMFCALANGGCLVIAPSEMRRDPVELTNLVH
                     NSQISLTIATPSEYLAWLRYGTASLKDHTIWRHACMGGEPVSRQLKTEFWRLDLANLQL
                     TNCYGPTEITAAATFETIRLDDQDDDNDRAQHAVGKALPNYSVRILDTAGRPQPVDHIG
                     EICIGGASVALGYLGLPEQTKAKFTVDPVSGERLYLTGDKGKLLSDGTLLCLGRLD"
     CDS_motif       complement(10143..10232)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0014"
                     /evalue="5.20E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="iccA"
                     /protein_end="3427"
                     /protein_start="3397"
                     /score="34.8"
                     /tool="antismash"
                     /translation="PVDHIGEICIGGASVALGYLGLPEQTKAKF"
     CDS_motif       complement(10767..10823)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0013"
                     /evalue="3.70E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="iccA"
                     /protein_end="3219"
                     /protein_start="3200"
                     /score="22.6"
                     /tool="antismash"
                     /translation="AVLLFTSGSTGTPKGIMLS"
     CDS_motif       complement(11595..11708)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0012"
                     /evalue="4.80E-09"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="iccA"
                     /protein_end="2943"
                     /protein_start="2905"
                     /score="28.5"
                     /tool="antismash"
                     /translation="KALMAFAHSSAPLDMILDAVKAPRSSETTPLFQVAVNY"
     aSDomain        complement(11757..12632)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccA_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.10E-55"
                     /label="iccA_Condensation_LCL.1"
                     /locus_tag="iccA"
                     /protein_end="2889"
                     /protein_start="2597"
                     /score="178.5"
                     /tool="antismash"
                     /translation="RMSPAQARIWFLTKHLDDPSAYNMVFHYRVKGPLKTVRLRHALQV
                     ATGHHESLRTLFYSRLEDGQPMQGVMPASAYELKHVPGADEADLKKELALLKAREWDLE
                     NGRTFSVSVLSRAADEHDVVFGYHHIIMDVVGWYFFVRDLDRAYRMQPFDKKISGSYVD
                     YSVMQLSQKNTAAASDDLAFWQKEFSTVPDPIPLLPIAAVSARPTDSGRKVSHHEYLEL
                     DPAQNLAVKETCEKLRISPFHFHVAVLRALIGGYTNIDDMCIGVVDANRGDERFAQTVG
                     CFVNMLPVRVE"
     CDS_motif       complement(11763..11852)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0011"
                     /evalue="4.80E-09"
                     /label="C5_LCL_267-296"
                     /locus_tag="iccA"
                     /protein_end="2887"
                     /protein_start="2857"
                     /score="28.7"
                     /tool="antismash"
                     /translation="DMCIGVVDANRGDERFAQTVGCFVNMLPVR"
     CDS_motif       complement(12462..12575)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0010"
                     /evalue="3.10E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="iccA"
                     /protein_end="2654"
                     /protein_start="2616"
                     /score="29.2"
                     /tool="antismash"
                     /translation="SAYNMVFHYRVKGPLKTVRLRHALQVATGHHESLRTLF"
     aSDomain        complement(12969..13208)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccA_PKS_PP.1"
                     /evalue="3.70E-10"
                     /label="iccA_PKS_PP.1"
                     /locus_tag="iccA"
                     /protein_end="2485"
                     /protein_start="2405"
                     /score="32.0"
                     /tool="antismash"
                     /translation="TEDEAVDAVLDGFCAKLEAILQLREGSVKENVQRAVIDLGIDSLV
                     AVEIRTWFLKELGAEVPVVKILGGDTVLQICTTAA"
     aSModule        complement(12969..20416)
                     /complete
                     /domains="nrpspksdomains_iccA_PKS_KS.1"
                     /domains="nrpspksdomains_iccA_PKS_AT.1"
                     /domains="nrpspksdomains_iccA_PKS_DH.1"
                     /domains="nrpspksdomains_iccA_cMT.1"
                     /domains="nrpspksdomains_iccA_PKS_KR.1"
                     /domains="nrpspksdomains_iccA_PKS_PP.1"
                     /iterative
                     /locus_tags="iccA"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(13539..14066)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccA_PKS_KR.1"
                     /evalue="5.20E-54"
                     /label="iccA_PKS_KR.1"
                     /locus_tag="iccA"
                     /protein_end="2295"
                     /protein_start="2119"
                     /score="174.9"
                     /tool="antismash"
                     /translation="KTYLMVGAAGGLGLSICEWMIRNGAKNLIITSRKPQVDQNMIEEA
                     SRVGATVKVMAMDVSSKESVAEVVQQAQEIMPPIAGVCNAAMVLSDKMFLDMDVDQLNG
                     TLAAKVYGTEHLDAVFADAPLDFFIVLSSTATTIGNIGQANYHVANLFMTSLVAQRRAR
                     GLAGSVIHIGYVA"
     CDS_motif       complement(13584..13694)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0009"
                     /evalue="1.90E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="iccA"
                     /protein_end="2280"
                     /protein_start="2243"
                     /score="52.5"
                     /tool="antismash"
                     /translation="LDFFIVLSSTATTIGNIGQANYHVANLFMTSLVAQRR"
     CDS_motif       complement(13968..14063)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0008"
                     /evalue="1.60E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="iccA"
                     /protein_end="2152"
                     /protein_start="2120"
                     /score="49.5"
                     /tool="antismash"
                     /translation="TYLMVGAAGGLGLSICEWMIRNGAKNLIITSR"
     aSDomain        complement(join(15588..16085,16133..16288))
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccA_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="4.00E-83"
                     /label="iccA_cMT.1"
                     /locus_tag="iccA"
                     /protein_end="1612"
                     /protein_start="1394"
                     /score="270.9"
                     /tool="antismash"
                     /translation="LEVMSKDDMLNRFYMDNCAARINNDIAKVVKQISFKFPRANILEI
                     GAGTGGTTWSILKDINDAYDSYTFTDISSGFFPKAAEKFSDFAHKMIFKTLDVEKQPSE
                     QGFAENSYDVIVAANVLHATRSLETTLRNARSLLRPGGYLILMEITNPESLRTTFIFGG
                     FSGWWLSEEPHRKLGPVVTAMDWDTVLNDTGYSGADMVVHDLAEESKHLTSLIVS"
     aSDomain        complement(17078..17611)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccA_PKS_DH.1"
                     /evalue="3.50E-26"
                     /label="iccA_PKS_DH.1"
                     /locus_tag="iccA"
                     /protein_end="1131"
                     /protein_start="953"
                     /score="84.5"
                     /tool="antismash"
                     /translation="HELLGRRTPDDNEFELRWRNVLKLSEMPWLRGHEVLEEVLLPGAA
                     YVSIAVEASKHIATSKGKSIELLEVEDVDIQRPVVVPDNKEGVETLFTARLLPGSSSDK
                     VLKALFSYYICNDQSTGTMVHTCSGRLSVHLGEAKEDVLPQRDPVPQNLVNINTDRAYG
                     MFKDIGLNYTGVFRS"
     CDS_motif       complement(17453..17527)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0007"
                     /evalue="3.60E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="iccA"
                     /protein_end="1006"
                     /protein_start="981"
                     /score="25.9"
                     /tool="antismash"
                     /translation="WLRGHEVLEEVLLPGAAYVSIAVEA"
     aSDomain        complement(17837..18793)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccA_PKS_AT.1"
                     /evalue="5.50E-88"
                     /label="iccA_PKS_AT.1"
                     /locus_tag="iccA"
                     /protein_end="878"
                     /protein_start="559"
                     /score="287.1"
                     /tool="antismash"
                     /translation="VFTGQGAQWPQMGKELIGKSPIFRRTLEDCDATLQALPSSDIPKW
                     SLVKELMANASSSRVAEAAISQPLCTAVQLGLVNMLKASGLNFDAVVGHSSGEIAATYA
                     SGIINLQAAIQIAYYRGFHAKLAKGEKGQQGGMLAAGLTLDKAKQLCLREEFVGRLQVA
                     ASNAPQTVTLSGDLDAIEEVKKYLDEENVFARQLKVDTAYHSHHMKPCAEPYLKSLLAC
                     DIEVRKPTPGQCIWNSSVRGDTGLLKGDLSSLKGPYWVANMVQTVLFSQAVESSIWHGG
                     PWDLAIEVGPHPALKGPTEQTLKAVYGVVPLYTGVLKR"
     CDS_motif       complement(18437..18538)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0006"
                     /evalue="1.00E-08"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="iccA"
                     /protein_end="678"
                     /protein_start="644"
                     /score="27.7"
                     /tool="antismash"
                     /translation="LNFDAVVGHSSGEIAATYASGIINLQAAIQIAYY"
     CDS_motif       complement(18743..18793)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0005"
                     /evalue="7.50E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="iccA"
                     /protein_end="576"
                     /protein_start="559"
                     /score="15.3"
                     /tool="antismash"
                     /translation="VFTGQGAQWPQMGKELI"
     aSDomain        complement(19133..20416)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccA_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.50E-166"
                     /label="iccA_PKS_KS.1"
                     /locus_tag="iccA"
                     /protein_end="446"
                     /protein_start="18"
                     /score="546.4"
                     /tool="antismash"
                     /translation="VAIVGSSCRFPGSSNSPSKLWDLLRQPRDVLKEFDPDRLNLKRFY
                     HPDGDTHGSTDVTNKSYLLEEDSRLFDASFFTINPAEAAGMDPQQRILLETVYEAFESA
                     GMTLEQLRGSLTAVHVGTMTNDYAGIQLRDLETIAKYNATGTANSIVSNRISYVFDLKG
                     PSETIDTACSSSLVALHHAARGLLNGDCETAVVAGVNLIYDAASYIAESKLHMLSPDSQ
                     SRMWDKSANGYARGEGAAALLLKPLSRALRDGDHIEGVIRATGVNSDGQSPGITMPFAP
                     TQAALIRQTYRRAGLDPVKDRPQYFECHGTGTPAGDPVEARAISEAFEPSADNPIYVGS
                     IKTIIGHLEGCAGLAGVMKVILALKNRTIPPNMLFNELNPAIAPFYGPLQIPKKAMPWP
                     ELPENTPIRASVNSFGFGGTNAHVIIESF"
     CDS_motif       complement(19457..19504)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0004"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="iccA"
                     /protein_end="338"
                     /protein_start="322"
                     /score="11.2"
                     /tool="antismash"
                     /translation="YFECHGTGTPAGDPVE"
     CDS_motif       complement(19703..19741)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0003"
                     /evalue="1.70E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="iccA"
                     /protein_end="256"
                     /protein_start="243"
                     /score="11.6"
                     /tool="antismash"
                     /translation="WDKSANGYARGEG"
     CDS_motif       complement(19787..19855)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0002"
                     /evalue="1.20E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="iccA"
                     /protein_end="228"
                     /protein_start="205"
                     /score="2.4"
                     /tool="antismash"
                     /translation="NGDCETAVVAGVNLIYDAASYIA"
     CDS_motif       complement(19883..19930)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_iccA_0001"
                     /evalue="4.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="iccA"
                     /protein_end="196"
                     /protein_start="180"
                     /score="18.7"
                     /tool="antismash"
                     /translation="GPSETIDTACSSSLVA"
     mRNA            join(<21712..22281,22334..22862,22921..>23336)
                     /gene="iccC"
                     /product="ring expansion P450"
     gene            <21712..>23336
                     /gene="iccC"
     CDS             join(21712..22281,22334..22862,22921..23336)
                     /codon_start=1
                     /gene="iccC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /note="IccC"
                     /product="ring expansion P450"
                     /protein_id="QBQ83705.1"
                     /sec_met_domain="p450 (E-value: 9.5e-50, bitscore: 158.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITLQNLPWILLYTGFLAIFLSRLFSNGKQSRDEKANGCQPPARY
                     PQWDPIMGLDLVYSQVSALKNNRYLEWLRDLHAKMPKTFSLNFFGQRWIYSIEPEILKA
                     VYATNFRDFGVEPIRRHSKGSMPFADKGVNTTDGEDWEFSRLLIKPFFERNVYTDTDRI
                     KVHADHFLSLIPADGETFDAQPLVQRWFLDLTTEFIFGESMGSLAHPERADIAWTMLDV
                     LRGGRLRAQMHRFMWARDWTWWLKAVYKVHDYVNPYIRSTLKELAEREERIKQGLPVGP
                     ERTDLVWSMATHLRDEELLRSQLCLIIVPNNDTTSIFISNCLWHLARHPEVWKKLREEV
                     FALGEETPLTFEILRNMKYLNGVLNETHRVIPNNVTQVRACVQDTVLPVGGGPDGKWPV
                     QVRKGDIVSVTKTVMYRDPDYWGSDADEFRPERFDGLRGTWNFLPFGGGPRRCPAQMMS
                     QTEAAYMLCRLARTYSRIEARDPEPYTAVMRIGPSNKTGVKIALYK"
     mRNA            complement(join(<28927..29329,29406..29629,29689..>30159))
                     /gene="iccH"
                     /product="short-chain dehydrogenase TIC 32"
     gene            complement(<28927..>30159)
                     /gene="iccH"
     CDS             complement(join(28927..29329,29406..29629,29689..30159))
                     /codon_start=1
                     /gene="iccH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /note="IccH"
                     /product="short-chain dehydrogenase TIC 32"
                     /protein_id="QBQ83706.1"
                     /transl_table=11
                     /translation="MNQQGTVIVTGANGGLGNAIVSHILDRQDLNTNYYGIYTVRDTVR
                     GARTVLRTLEWAKSVKHSHELLAIDLGSLDSVRRAARDINSRVANGTIPPIRALILNAG
                     WGEQTTHSFTNDGFDMSFQVNYLSHFLLTLLLLQSMDKKHGRIEVLGSWTHEYLIPGVS
                     TCSTTDPNNKKGPSASMYTPKRYQQIFNYPINTEDLAKGKWSSEREHPGDLNAGLRRYG
                     AAKLCEIMMFRELSNRIEKDPELSAISVVAVDPGAMPSELNRRSIWVMFLLMKFVLPLL
                     APLAVWLQPNGTIRTTTKSARDVVRAAFDTATLGDHPNGIYLNGSEIADVGPEAKDAEK
                     SRTLWHDSLVYARLEKGDTILKAWE"
     mRNA            join(<30654..30831,31017..31687,31749..32096,32161..>32208)
                     /gene="iccE"
                     /product="epimerase"
     gene            <30654..>32208
                     /gene="iccE"
     CDS             join(30654..30831,31017..31687,31749..32096,32161..32208)
                     /codon_start=1
                     /gene="iccE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /note="IccE"
                     /product="epimerase"
                     /protein_id="QBQ83707.1"
                     /transl_table=11
                     /translation="MADLHLAKSITLRCGLTLPNRLAKTAIAESIAPRNMLIDEGFHRV
                     YAPWAEGGWGMVLTGHVQVDSMHLGTHTDPAVNADFSDDQIVGSWKVWAAVCNRHGTPT
                     IMQLNHPGRQAPIGAGTSGVFAKNISASAVPMDIGSGLLARAVSKIVFGTPREMTVDDI
                     GKLVRQFARAARLASQSGFAGVELHASHGYLLAQFLSAATNRRKDAYGGTPANRARIVV
                     EIIKAVRAEVPASFCVGIILTAVHGSASTEEFQSFIEQAQLICDAGVDFIEISGGTFET
                     PSMFIGPEKRGKAYDWDNQEAFFLDFAQAIRPHLGTVPLLLTGGFRSCHAMEAAVKRGD
                     CDMIGLARPAVVNPLLPKTVVFNPEVNKSGDTKLHATRTPAPWYIKLFGITALNVHMDN
                     AWYVGRLQTLAKTGR"
     mRNA            complement(join(<32464..33166,33233..>33408))
                     /gene="iccD"
                     /product="Diels-Alderase"
     gene            complement(<32464..>33408)
                     /gene="iccD"
     CDS             complement(join(32464..33166,33233..33408))
                     /NRPS_PKS="Domain: oMT (54-241). E-value: 1.7e-19. Score:
                     61.2. Matches aSDomain: nrpspksdomains_iccD_oMT.1"
                     /codon_start=1
                     /gene="iccD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /note="IccD"
                     /product="Diels-Alderase"
                     /protein_id="QBQ83708.1"
                     /sec_met_domain="PCMT (E-value: 6.6e-08, bitscore: 21.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASSEVFTSEEAAQRAIKTYYESQESRMGYELVFGGTQHFGYYTP
                     GTWSPFPIDKSLRRMEEKLMGWLALPAGSRILEAGCGVGHVALYLAKHGMRVTGVDIID
                     HHVEQARRSAQKANLPKDQIVIEKMDFERLEAIPSASHDGAFTMQSLGHAFSAEKALAG
                     FFRVLKPGGRFALVEVERRPNAEADKKNPRLTEQLSMINVGTGMPTNERSHDGFYKGLL
                     EEAGFVDIESRDISDNILPVVRMFYVVLLVPYLFVRLLGIEKHFVSMLAGTAGYVGYDR
                     WRFMVVTGRKP"
     aSDomain        complement(join(32620..33166,33233..33246))
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccD_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.70E-19"
                     /label="iccD_oMT.1"
                     /locus_tag="iccD"
                     /protein_end="241"
                     /protein_start="54"
                     /score="61.2"
                     /tool="antismash"
                     /translation="KSLRRMEEKLMGWLALPAGSRILEAGCGVGHVALYLAKHGMRVTG
                     VDIIDHHVEQARRSAQKANLPKDQIVIEKMDFERLEAIPSASHDGAFTMQSLGHAFSAE
                     KALAGFFRVLKPGGRFALVEVERRPNAEADKKNPRLTEQLSMINVGTGMPTNERSHDGF
                     YKGLLEEAGFVDIESRDISDNILP"
     mRNA            join(<33889..34122,34174..>35550)
                     /gene="iccF"
                     /product="cytochrome P450"
     gene            <33889..>35550
                     /gene="iccF"
     CDS             join(33889..34122,34174..35550)
                     /codon_start=1
                     /gene="iccF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /note="IccF"
                     /product="cytochrome P450"
                     /protein_id="QBQ83709.1"
                     /sec_met_domain="p450 (E-value: 1.5e-37, bitscore: 118.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPLATYLSQIDDYPKWALFTGGSIVLFFLYRIFLSPPSYPPGVP
                     LIAEPAGRTWFSPKTRWRYYTDCASLYLEAYNQYSKKGKPVVVPGFGLGYELIMPESLM
                     SWVMAQPDSAISVNQAFLDINKTKYSLGHTRYWGDTWQFVLVKTQLNSVLQYLIPGLND
                     ELKLAFDAHFGTDTENWKEIELEKVLKNVIAQAASRFIVGAPLCRNEKYLKANYGVIEG
                     MMLNAIFTNSSPKWLQPIIGPLVSKKSINNCEIVKKEFEPLFRERLETLKHDKDDPNFE
                     EPQDHLQLLLRYAVKERKDELNDLDIIAKRIIAVNFASMNQTTMTVVNMLLNILGSDAE
                     FNTIAVLRDEMKRTTSDGEPWTKAKLATMIRTDSVVRETLRINPFGNRSLMRKVIKEGL
                     VTPDGMKLPKNSLFSFFSEPVQHDPDKFEDPFKYDPFRTSREREAAADEEGKPGGHALT
                     VVSTSPNYLPWGHGKHACPGRFLVDCEMKMLLTYVLSNYDIEFPVEYNGQRPPTIWLAE
                     VGLPPRGAKIRVKRRKEAI"
     mRNA            complement(<36132..>37259)
                     /gene="iccB"
                     /product="trans-enoyl reductase"
     gene            complement(<36132..>37259)
                     /gene="iccB"
     CDS             complement(36132..37259)
                     /NRPS_PKS="Domain: PKS_ER (24-245). E-value: 3.2e-20.
                     Score: 64.4. Matches aSDomain:
                     nrpspksdomains_iccB_PKS_ER.1"
                     /codon_start=1
                     /gene="iccB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /note="IccB"
                     /product="trans-enoyl reductase"
                     /protein_id="QBQ83710.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.5e-14, bitscore:
                     42.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDATLPSIHTALKILGPNNVSVSENTALPVIQPLDILVRVACISI
                     NHVDAKSADMSPSPGATSGTDFSGVVVAIGSDVPKESFRSTNGMKPVQIGDRVFGGVFG
                     NNPLRRDNGAFAEYVAVPARLVWHIPGGMDFSTASTLGAAVATVGLSLFQYMQLPMPTT
                     TSTASPDNGPFVLVYGGGTATGAMAIQVLKIAGFRPITTCSSASAGHATELGATATFDY
                     RSPTCGAELREHTGDTLTLALDCITDTASMNICYEALGSSGGRYVALDSFPLRAHTRRS
                     VVPDWVCTYSQFGHPIAWAAPYNLEARPEDLLTAEAWYVVAQKLIDQGLITPHPKEERL
                     GGLAAIGEGMEAVRRGQIKGKKLVYPISNELCAAA"
     aSDomain        complement(36525..37187)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_iccB_PKS_ER.1"
                     /evalue="3.20E-20"
                     /label="iccB_PKS_ER.1"
                     /locus_tag="iccB"
                     /protein_end="245"
                     /protein_start="24"
                     /score="64.4"
                     /tool="antismash"
                     /translation="NTALPVIQPLDILVRVACISINHVDAKSADMSPSPGATSGTDFSG
                     VVVAIGSDVPKESFRSTNGMKPVQIGDRVFGGVFGNNPLRRDNGAFAEYVAVPARLVWH
                     IPGGMDFSTASTLGAAVATVGLSLFQYMQLPMPTTTSTASPDNGPFVLVYGGGTATGAM
                     AIQVLKIAGFRPITTCSSASAGHATELGATATFDYRSPTCGAELREHTGDTLTLALDC"
     mRNA            join(<38367..38544,38632..39620,39692..>39745)
                     /gene="iccG"
                     /product="NADH-dependent flavin oxidoreductase"
     gene            <38367..>39745
                     /gene="iccG"
     CDS             join(38367..38544,38632..39620,39692..39745)
                     /codon_start=1
                     /gene="iccG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /note="IccG"
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="QBQ83711.1"
                     /transl_table=11
                     /translation="MDLNLAKPITLRCGITLPNRLWKAAMTEEFADKRRLPGSEACLAT
                     YRVWANGGWGLVMTGNVDVDPAYLGSPGNIAVDSSIPREKTLAAWRAWAEACSQNGAKA
                     IVQINHPGRQASFTKSIAPSAVPLNLGPGILPWMLRSLIYGTPREMTVDEIHDVIMKFA
                     ETARLAADAGFAGVEIHAAHGYLLAQFLSAASNKRTDAYGGSAKARAKIVIDIIHAIRS
                     DVPKTFCVGIKFNSTDHQSETEMKDCLEQLHLISDAGVDFLEISGGTFENPTFNLGVSD
                     QKAKVSTQTREAFFVDFAKSIRSELSGLPLMVTGGFRTRQGMETALVEDSCDVVGIARP
                     AVLSPYLPRNIIFNRDVVDAEAIAHAEKIDTPTIAKWMGIKAIGVGAETIWYIKKIQNL
                     GSIETEL"
ORIGIN
        1 ttaattacat acgagtcagg ttgctgatac agccttaagt acgtaccgtt atgatttatc
       61 caagtacaat gtgcgtatac gtcaactggt gccctcggcg gagcatacaa acggtgtaca
      121 cccgccattc tggtaccaac gagtgactga aatatacgaa gatttgacgc caagaatgac
      181 cccatcgggc aattccacca ttcgttgcgt tttaattgac gccgacgaaa aggatagacg
      241 caccgccatc cacacttgaa gcactcggca tacgtccgag aatctttgaa agtctgcggt
      301 tcagcaaatc ttcaagtgcc tagtcatgcc caatcaacct ggggcattaa aaggatgatt
      361 gcccctgtcg gtggcttttt ttaccttttc tcgagtgctg tggggcgatc tccacccggg
      421 tactttatct gatttacgga gtacgctggt actccgtagt gctgctttta gtccttgtct
      481 ttacttttaa gtttcgtttg gaaggtctgc taatcttggc ttactcctcg ttgtaaagaa
      541 gcttacccaa gatcggcgcc ggccgcgcta ttattactgc cctcttcgta cagggggcca
      601 atatcgccga tgcacagacc ttgcatgctt gcttaatatt cttgtcatgt ttcataaaag
      661 aaatgaccga tattgtcact acagaatata cccatgttct ttgtaagatc agagaatttt
      721 tcaagcctgt taggtagtag agtagcccat aactgttatg gtagtatacg aagtggaacg
      781 aactgctact taaagcatat catggggcaa cagcttagtc acagcaataa taataagctt
      841 atgcctagag tttaaaagtc taaacgctca gctggtgggt ctgttggcca ggataaagct
      901 gtgggttttc caacacgtcg acaattgtgc aatgtggagt aacggggcgt cctaacaacc
      961 taaacagcat aataaagtct attattgata gggcttattc ccatctgtat ggaacagcga
     1021 attgcctgtt tgggaccgta tagaatggcc cgccaagttc accctaacgt tcggaaaacg
     1081 ccgcttcgga aacgactgcg acaaccctgt attaatatca tcattattat ttatccactg
     1141 ttgatttgga atgtcatgtt tagtacatcc gtcgcttttc acctcgttca ccatgtaccg
     1201 ttaatagtcg cccttgtact atgactcgtg tccactataa cagcgaaaaa tcctgagtca
     1261 gtgtcaactg gtgttgaact aaatatacaa acgtaatatc ttaaaacacc gcgaactggg
     1321 tattgagaga aaaaaattgt tacaggtcga gggagaaaaa agatattata catgcaatgc
     1381 agtagctaat taattaatgg ccgccctgct cgttgccctc gttttcttta ttcttcttgc
     1441 caacgttctt ccatccaaca ccaaatgcga agatgagttg cacgacagaa aggcctacgt
     1501 taagatagaa tacgtcgcca atactttggc tgtagacttt caagacggcc tgtagatctt
     1561 tggcgggcac caggtcccga aatcccgtcg caccggcgtt gacaagcaac tcggcattaa
     1621 cgtcaggagc agcttgcggt aacttgcttc tcagagcctg ggagaatata acttgggcta
     1681 ttgccaggaa gatggagccc ccgaaagact ggccagtggt aagaatggcc atggccgtcg
     1741 cagtatcgtc agatccagcc gcgttctgaa cagcaaccat aggctagtaa ggcaaaagtc
     1801 aattagcaaa aagtttaatg agatagaatg gagaagcaca aaaacttaaa acgaattcat
     1861 ccaggaattc gccgtcggcg acttactact tgtgccacag cgccccggcc aagaccattt
     1921 agtccctggt aggcggccca taccgctgtc gaagtagatg ggctcaaggt tgtgagcagc
     1981 ccattactga tagtgttcaa aactcctccg atgacaccga atggtaggta gtacccaatt
     2041 ttcccagctg tcaaaaaagc acgcgtaaga gagaatattc ccacatgaga caaaatgacg
     2101 ggtgagctac ttactaagaa taccagcaac aagagctgca acaatctgga acactacgct
     2161 ggggagcatg tctacaccac tcgtgatggc tgacttgttc tggaccgcct ggaagtagat
     2221 ggggatgtag taggaaaacg ccatgatcat tccaaacacc agcatcgata tgaaacagct
     2281 gcataagatg atccggtttc ggagaattgc cccggggatc atggcatctt caccgacacg
     2341 gtgctcccat gcgataaaga tggcatatgt tacaccggca ccccagaaga ggttgatgat
     2401 agtagggctg ttccatgcat atctggtacc tccaaattcc aacgcgatga ggaacattac
     2461 agatgccggg gcaaacaagg cgaatcctat gaggtcaaat ttccttagga cgacggttcg
     2521 cagtacctcc attggcggtg gtttcgcttt ttgatcgggg attcgcgtga agaatagcaa
     2581 gactccgacg acggctccga tgggcaggtt aacatagaag cctatacata ccacggatat
     2641 cagtaaattg gttatgcatc gggatatgga aacaaaagta cttacaccac ctccatgtcg
     2701 agtacgtggt aaaggcacct ccgactatag gtccacaaac ggcccctaac tgtgagactg
     2761 aaggggggat cagtcgatat atgcttatct tgtgtgttca gaagatgttt gcaaactact
     2821 tacttcccat aataatccca atcagagctg gaacgcatag tcagcgctgg cgacccatgt
     2881 ggaattcaaa ttgcctcata cctggtcttt tgtgcattgg caccgaaccg gcgatgatat
     2941 tcaatgcacc attcataata cccgaagttc ccattccagc cacggcgcgg ccaacgatca
     3001 acattttgga cgaattcgcc aggccacaaa tcaaagaccc cagctcgaaa atggcaaaga
     3061 aagtgaggaa tgaccactaa catggatata attagcattt atccggggtt cgtttctctg
     3121 tacaaacctt ggtcttgaaa tatgtgtaac atttcccggt gagcggctgt agacatgcac
     3181 ttgaaatcgt gaaagcgctg ccataccaac ccacgtcatt caaagaatga aattcacttg
     3241 ttatattggg ggttgcctat attgaaccag aatatgtcag tgaacttccc aatcactttc
     3301 caaccgtacg taatcaaaag gtaatgccga ccgtggctaa aatggccgtg tcaaggagca
     3361 tcaggaacac gaccagcgtg atacccgtgg tcaccatgac aagcggtaaa ccttgcaccc
     3421 attgttgtcc tttctcttta tcgtctatca attccatact ggctatcgtc cctctgcttg
     3481 gcgacggaag agcggtcatt gttcgtgtcg acgaagcatc cgaggccaca tcctcccggc
     3541 tcatccccag ataaggagag taggcactcg acggccctag ggagggacgc gaatcaatca
     3601 tgagtgcaac ttattgaggt cgtgtgagca tttgaatgca gaggcaactt ccgagttcct
     3661 cggtggtggg gagaaaagtg ctttatatta acaaaaaacg aaagcagagt cgaaaggaga
     3721 gaatttgttg ctattgaaaa gacaatatcg agctaatgag gtcactgtaa agtaaataat
     3781 aataagggct tcgagaattt tcgctgcatt gctagcgggg attcttctat gccagagtgt
     3841 gacagagtat ggaattgctg ctgaccggag ttggggcttt gccgtccccg tgcatccatc
     3901 tacggccccc gaacgtgctc ttcgtcgcgg gccaatgcaa gatcggcgag tagaataatc
     3961 atgcaaggcc tactacgtat catattacgc tctatagcct ggaaatagta tatgcatggt
     4021 aatgtagatc cacgtgtcgc acgtgttggc atcacgctgc attcccggtt tctgtcaaga
     4081 tggccagtca caaactaaca attcatgatt gatgggtgtt aaaataaatg atttaaatct
     4141 atattatttt aataatacat atatatttac agtccagcaa gaggtccagc cgccaatggg
     4201 tccgtcaacc agatgctttc gggccacgcc agaaagttat ccatataccc catttccgta
     4261 ttgggtaacg agggtccccc ggcagcttct gtcgcctgat gaccgctgtc ggccatgcga
     4321 gatgcccatg ctgcgcgcaa cttgagcata tccctggctg agatgctaaa tgagtcatcg
     4381 tccgaccctt cgttgtcaat accggccgat tgagcgacct ggcccagctg cactgctagc
     4441 cgctccgcta tcgaaagcag gtccacagta ctgcgtacaa ctgttttgtc ccagccagga
     4501 caatcgagaa tagatagccg aaaaagagag ttaagagtgt gtgatatttg aaccaaaatc
     4561 ggcagcggta agctgatgaa agtagccggc ggggaagata acagtagatc gaagaattct
     4621 ttcactgcct gtagacatgt atataggtag tttaactggc tgatactaga cacttcgctc
     4681 gttttattcg gtggttgaag ggcaatttca tagagacata tcttggtgtg caggtagtga
     4741 agacgaacgg gctctggtag attagttagt aatgtttccc tataccggat aggataaatt
     4801 tgaaaaagaa agggaactca tacggttttc ataaatctcc gctgggactt tgtttatcaa
     4861 ttcaattagt tgggattcaa aagcattgat atgaaaagca gcaggtgctc tgtttatctg
     4921 cctgtctccc gcatgctcga cattccaagg tccctgtgac attttatcca ccatcaacca
     4981 aaacgagaca agctggacaa ggactatatc gtttggtgtt tcgcgactct ccgttagcat
     5041 gtccagacat tctgacatgt gcgatgtcca tgataacgtg tttgttctcc ctaaaaattg
     5101 tgagatactt gtattttatg taggttagta ttttgtaatg taatattttt ttttcagacc
     5161 aacataccat gaactaatca gaaagcaacc aagtacggct cgtcgctggt tcatggttct
     5221 aacattggcc gccggcggct tgaagcgggg attgtatgcc atggcagcac agtgcgcaag
     5281 agccgcgcta gaatctaacg gaggagtctt gttgagacca agctcgaata ccagcccgat
     5341 agccagctga atgtacatac ccagcgaggt ctggcgggac ggacagtggt atgtaatcct
     5401 acattgcgaa tccgaatgtt agctctccac gagggacaat cacaactgaa gaatagagct
     5461 cttaccatgc tagatatgct aggagtcctt ggagtagatc gagactcttc tcgttattaa
     5521 ccaacaatct gcggccaaca atatcaccaa attgcttact caaggcggtg gattgaccag
     5581 ccgatttgga ttcgataatg gtgacacagt gccataaaca cgggtattca tacttgaggt
     5641 cctttgcttt gaccgttgcc ggtatgtgaa tgaatggaaa atatctaagt ttagtggtac
     5701 gaaacgaggc cagcagctcg tcttcggcag ttacagtgat atgaggccta tttgaggccg
     5761 ggatgtccag taaactgtca ttttcgtgtg cagatgctgg aggagtatcc tcgccggaac
     5821 ctaaccgggc tactccgggg agagcagcag gcccgggcga gggctggtcg cccgacttta
     5881 gtagagagac cagctggttt acagttcgct ccagctgggc tgtccgagac agcggcttgg
     5941 gcttgcgaac tcggttggct ggtcggcatt ccttgctcag tcgacgacac ctatagacgc
     6001 cccgccagtt aaccccttgc tttcttgcat cattgaacac gatttctgcg tatgggttgg
     6061 ttttttaccc tttcaatgca gagcaagtgc caaaaagcaa caaatacgta cctttcacac
     6121 cccccaccac tattccagtt gacgcattta cacttggccc gagcgcagtt ggcacacgcg
     6181 tgcccgtacg gcgccgacga gataccggaa tcaatgtcca tggaattccc atctgccttg
     6241 gatttcaaat cgatggtggg tgggggctgg cttgaagctg agaagcctga gaacgcagcg
     6301 tcggcgaatt ccgagtgagc gaggggagca agagagctgc gagaacagga attccggcga
     6361 ctctggcgga tggccgtctt aatatagttt gtgcacggac ggggatgaca gccggaattc
     6421 cgtccgttcg gcctccgccg cggggaatct gatcggcgcc gaagccctat acaattttat
     6481 tcgcagtact tatattcagg ccattcccgg tgacaaagca gggtggaaca agggaaccaa
     6541 cacacaccca acacataccc aacacaaaag gccatacgga aagatacgag agaacagagc
     6601 attatccaat ccacccggat aacccttgcc gatgaacgaa aagaggcccc ggtcaccgcc
     6661 ggggccaact gcatcacgga gagacgtcgc ctacaggccg gtggtaataa agacgactgg
     6721 tctcacgcat acatacgtaa tgtagcgttc tacccttttt tggtgatctt gcttggctgt
     6781 tcaataatgc gtctcgtata accctcctcg ccccttcttg atgcaatgcg cctacgggat
     6841 agagtggcac gaccaggatc gtcaaaccat atgctacgga gatttcttgt gtcaggtcag
     6901 gtgcggtatc ttgagtatgt ttttgctttt tgctctcctt tcttttgttt ttaaagcttc
     6961 acccccctgg tcgctttggg agattcccgg cccaacagga atctctgata tcagttgatt
     7021 ctgacccatg ctattactcc atactccgta aattagaaat acgtaacact tagacgatca
     7081 agcgtagcat tattagagta gaggggccaa gatcagccga ctagtagttc ggtgcgcaat
     7141 tcttaaagct attaaaattt aaagcctttc ggccccctcc ccagtctcca ctgtggagtt
     7201 catccttgtt ttttcgtaca ctactagctc tgacaatgcc ataatacacg acggttacat
     7261 ggttttaaca agccaaactt ctcatcgaaa tgccttatac agtttagtgc cgtaacatgc
     7321 tggtaagaac tagcagtgtg atacggatcg ctgatcaacc ggtggatctc ggccgtacgc
     7381 ctacacttgg cgggacaatc atagcgattc tgtttcagat gacggccatt gactgctgct
     7441 aatttctgcc ctagggggca attaggttct gagaccacga ggcaggatca agccaaccct
     7501 tagtctgaat tccttcgctc gtgcccgtct cccctatagg aagacttttc gacttggcat
     7561 tgtccgtcat acctgtcagc attgatttga atttgaattt ccaagccttc ttccttaagt
     7621 caatgaatta gttttacacc ttgcgtagtt ttcctgtttg aataggtgac tgccagtcta
     7681 tttcaaatcc ccagctggcc tgttccgtaa ataagctaag tatgtatatg ttaagttgca
     7741 agcaatcggc gtcaacgaca tatggatatc tgaccttgta ttgtagtttg tagatttatc
     7801 cagccaaggt gcgcaaataa cattgaatat attttgtaca tttttgtagg cactcaactt
     7861 ccaatgttgt taaactatat acatgtagtt ttaaataaaa ttatacatac ataacactga
     7921 tataaataaa tccacatgaa gtaaaatgag aaaagtttta attattataa gattcaaatg
     7981 ttgtgccata tatgtcaact ggtatgtcta cctatcaatt gatgtatatc atggatagat
     8041 tcagcttcag cattggaatc aatggatatt caaatacgta tgtattcaaa tgttggtttg
     8101 catacattca ttgatatata ctgggctatt acagccaagc accattgaag ttttcaatta
     8161 aaataaaatc accttgaaag aggtgattaa agaagctcgt taaatacatg atgtcaaaca
     8221 cgcaacaaaa acgtatcgta tatacaattc accgaaaaca atgccacatg ataaaactcc
     8281 aaatgtcatg aatcaatcca caaatacatc aaaaacataa tccaaaagac aagacaaaac
     8341 ggaagaaaga aaaaaaagcg aaaagataat aaatttcata cagtctctcc caagtaggga
     8401 aatacgatag gcgctccagc ctcaatgatt ccctccatat atgcggtgat caacgggtcg
     8461 aggccagccg cggcagcacg gtgcatccat tcttccaagt gcacttcttc gaagttacct
     8521 ccgtaaacgt tctccatatg aaccttgaag tcaccaatag ggaccttgac tcctcctgaa
     8581 tgatgctgga atcggatgct gggctgatca gtgacattcc ccgtagccat ttcgatggca
     8641 gattcagcca tgctatcaac aatgctctcc actgaagcga agtccaagta gcccgtggcg
     8701 ctctcaagat gtgggacaca tttcatggaa gcggaataac gtagaattgc gttcaacgcg
     8761 tcagagttag gagcatgctc actaaccact acgcatggcc gatgtacgga agcaacccac
     8821 ggccgaggag cctttttctg aaccgcaccc actaactttt cgaggaaaac ctcacttgcc
     8881 cattttgtgg cagtatatcc ctcacggcca tctgttgctg gtgggaatgc cgcgacagag
     8941 gttggcggta aagctgtgtt tcctgataac aacggaacgc ggttcgagga tagaagtaag
     9001 agagggattg agcgcggcaa tgccaatgat gcaaggaact gaagggaaac aagatttggt
     9061 gtacgcaatg agccgtacgt gttgaggcag tgcccacttg atccagcgtg aatgacgacg
     9121 tcgacatttc gtgcgagttg gtcgcgctca ccattgttca ggccgagtgt ggaagacagt
     9181 agactgccag tgtaacattt gactttttca tcctggtaga gttgatcctg ctcatccgcc
     9241 aatacagcga cacagtgtac tttgcgcaca gacggggatc gtactaaaga cctcagcaag
     9301 cgcccaccga tgaagctcgt cgcaccagtc atcaaaatat caatgccatt aggcttcgga
     9361 ggttgctttg tcgttttagg caggtcttct atttgatcaa gaagccactt cggtaatgag
     9421 gtctcggctt gccagtcgaa atgttgttca agggcatcgg cctgctcttc tcgctgttcg
     9481 tcaacgcaca gagccatttc tcgcagagtg ctagcctggt ataggacacg ggtagaaatt
     9541 tcgatcccaa ttgattcctt gatggcagct tgtagtttca tcaaaagcat ggagttacca
     9601 ccgcatagga agaagtcaga ggatgggcct agcggagtcg tggttgcagt gtctgggaga
     9661 acacgttccc atagtaaacg caactcgccc tcacggatat tcatcttttc ctgtggacct
     9721 tcttctccgg taactttttg agggagagga agggaagcga ttgccttccg atccaatttg
     9781 ccgttggcag tagtaggcat tgtaggtaag ataccgatgg tagcagggat gaagtattgc
     9841 ggcaacttga gacgactgag aatcttagcg agatccgatt cagaaggttc cgcttggctc
     9901 tgggaaatcg tggcgtgtgc aactagaatg cttcctcgag cagagacaac ggcactagaa
     9961 aacaaaccgt tcgccgtttg gatcaacgct gattcgacct cttgaagttc aatgcgaagg
    10021 ccgcgatgtt taatctgggt atcgccatca agacgaccaa ggcacagcaa agttccgtcg
    10081 gacaataact tacccttgtc cccagtgagg tacagtcttt caccggagac tgggtcgacg
    10141 gtaaacttag cctttgtttg ttctggcagc cctaggtaac ctagagccac acttgcaccg
    10201 cctatgcata tttccccaat atggtcaaca ggctgtggtc gccccgcggt atcaagtatg
    10261 cggacggaat agtttggtaa agccttgccc acggcgtgtt gggctctgtc attgtcatca
    10321 tcttgatcat ctagtcgaat ggtttcgaat gtggctgcag cagtaatctc tgtcgggcca
    10381 taacagtttg ttaattgaag atttgctagg tcgagacgcc aaaattcggt cttcaattgg
    10441 cgcgaaactg gctctccacc catacaggca tgacgccaga tcgtgtggtc cttcaacgat
    10501 gctgtaccgt aacgtaacca tgccaggtat tcagaagggg tggctatggt aagagaaatt
    10561 tgagagttgt ggactaagtt tgttaactcg actgggtctc gtctcatctc ggaaggtgca
    10621 atgaccaagc aacctccatt ggccaaagca caaaacatct gaataagaga catgtcaaat
    10681 cccattgagc tttgctgtag aacattttct tggccgagct gtagacggtc agttttgagg
    10741 gcgaggtgat tgacaaaatt ggcctgagag agcatgatgc ccttcggcgt gcctgtagaa
    10801 ccactggtaa ataggagcac tgcattattg tgtggttctg ccgcacatga cacggtttct
    10861 ttctcttcca cggaagatat ggtgtcgact tgcagcacag aaatggttga tccggtttca
    10921 ttgacaagat cttcaacacg atgtttagta gctgcatgag aaagaagaag agtcggttgg
    10981 ccgccgttca tcatagccgc atgacgagcg gtaggtaggc tcacatccat gggaatgtag
    11041 acgccaccta tatgaagagt cgccagcatg gagatgatgg catctgctga aggttcgcac
    11101 aaaactgcta cacgagagcc cttggaggct ccagcgcgaa ctatagctgc cgctaccaaa
    11161 tggatccgac tggccagttg ctcatacgat aaaagttccc ctttgaattg aatcgcggca
    11221 tttttcgggc tcttgaggca tgtttccaac acgcgatgag ataaggtaga cggccagcca
    11281 aagtcggttg tagggccctt accaatctgc agagcttcac tcaccttggc ctggtcgtga
    11341 atgacacagt ccttgagctt aacgtgagta ttcttgcaga aagtatccac gaggcgtaga
    11401 taagtgttca gcaaggtgcg agtggcatcg ctgctgtaca aggtcttctg gcaatgcatc
    11461 tcaataacac acccctttcc ggtttcggca ataccgagac taatatcaaa cggattctcg
    11521 gcatcctttc catcggtcag agacagcttc atctggcaat cgcccattgg cagatcccaa
    11581 actcctccag ttcgatagtt aactgcaact tggaatagtg gtgtggtctc tgatgaccta
    11641 ggggctttga ccgcgtcgag aatcatgtcc aaaggagcgg aagagtgagc aaatgccata
    11701 agagccttgc gagaggcgct tcgggctatg tcggcaaatg tggcatcgct aggagcttcg
    11761 acgcgtaccg gaagcatgtt gacgaaacag cctacggttt gggcgaaacg ctcgtctcca
    11821 cggttagcat cgacaactcc aatgcacatg tcgtcgatat tggtatagcc accgatgaga
    11881 gctcgcagaa cggcaacgtg aaaatggaag ggactaattc gaagtttctc gcatgtctcc
    11941 ttgacggcca aattttgcgc cggatcgagt tcgaggtact catggtggct cactttgcga
    12001 ccagaatcgg tgggacgagc gctcactgca gcaatcggca gaaggggaat tgggtctggc
    12061 acggtagaaa actctttctg ccaaaatgcg agatcatcgc tggctgctgc agtgttcttt
    12121 tggcttagct gcatcaccga gtagtcaaca taagagccag agatcttctt gtcaaaaggc
    12181 tgcatgcggt aggcgcgatc taagtctcgg acgaagaaat accagccgac aacatccatg
    12241 ataatgtgat ggtacccaaa caccacgtcg tgctcgtcgg ctgctcggct cagaaccgac
    12301 acgctgaaag tacgcccgtt ctcgagatcc cactcacgcg ccttgagcag ggccagctct
    12361 ttcttgaggt ctgcctcgtc ggcgccaggg acgtgtttca gttcgtacgc ggacgcgggc
    12421 atgacgccct gcatgggctg gccatcctcc aggcgggaat agaacagggt ccgcaggctc
    12481 tcgtgatggc cggtcgcaac ctgcagcgca tggcgaaggc ggacggtctt cagaggtcct
    12541 ttgacacggt agtggaaaac catgttgtaa gctgaggggt catctaagtg tttcgtcagg
    12601 aaccagatgc gggcttgcgc cggggacatt cgttcatcac gcaccgtctc tggcctgaca
    12661 tggctttgat ccttggaggt gtctggcaca ctctcgctgt cgctgagctc cttgggcgac
    12721 gaggcgccgg ttgcgctgga cgagctgccc ttgttggaga aggccgagtc gtcgccaacc
    12781 tcggagatgg tcgcgctgtc gggctcgaac gcccttgccg gcacgtccag cagggaaggc
    12841 gcgaccggcg caggcgtggg cgcggaggcg gcaggcgcgg gctccttctt gctcgcggct
    12901 tcacgtccac cttcttctgc aacagcgtct tcttctttct tcttcatcgc gttcgccatc
    12961 accttcttcg ccgcagtcgt gcagatctgc agcacggtgt cgccgcccag gatcttgact
    13021 acgggcacct cggcacccag ctccttcagg aaccaggtgc ggatctcgac ggccacaaga
    13081 gagtcaatgc ctaggtcgat gaccgcgcgc tggacgtttt ctttgacact gccctcgcgc
    13141 agttgcagaa tggcctccag tttggcgcag aagccgtcca gcaccgcgtc tactgcttcg
    13201 tcctctgtct gcgcctcctc gacttgccgg cgaacgctgc taccattgcc ggttccaccg
    13261 gtttggctgc tgtcgttttg cagggtgcta ggcactaggt gcccgaagca cgggttcgac
    13321 aaccacaagg tttggcgttc gggctccagt gggacgcttg cgggctcaag gcccatgatg
    13381 atatcaggcg agccgaccgt gtttccgggc cgtccaccac gcacagcttc agcaaatgca
    13441 tgatgaacgt cggtctcgga cagtgccatt aggcgcacgt tgcggaaatg ttgctcgagc
    13501 tgacgctcac ggtcctgacg agtcacataa ccaacatcgg caacgtatcc tatgtggatt
    13561 acagaccctg cgaggccacg agcccggcgt tgggcaacca agcttgtcat gaagagattg
    13621 gcaacgtggt agttcgcttg gccaatgtta ccgatggttg tcgcagtgga agagagcaca
    13681 atgaagaagt ccaagggagc atcggcaaac acagcgtcaa gatgttcagt gccgtaaacc
    13741 ttagctgcaa gcgtgccgtt aagctggtcg acgtccatgt ccaaaaacat cttgtcagag
    13801 aggaccatgg ccgcattgca cacgccagca attggaggca tgatttcctg tgcttgttgg
    13861 accacctcgg ccacagattc cttgctagaa acatccattg ccatcacctt cactgtcgca
    13921 ccaacccggc tagcctcctc aatcatgttt tggtccacct gaggcttgcg acttgtgata
    13981 atgaggtttt tggcaccatt acggatcatc cactcgcaaa tagacagacc caaaccacct
    14041 gctgcgccga ccatgaggta tgtcttgtcg gctttaaata tcccttccag gtcaagcggt
    14101 ggcacggaaa cgacaagtga atcccgctgc tgccagtctg tgacgtattt tttgtgcacc
    14161 aaagatagca tgttagtaag aggcaagtca cttgctggga acacttcgca ttcagattga
    14221 acctgttctt gggtaattaa ctgagttgca tattgatacg cttcctcaag aagagactct
    14281 ggcttggact ctgtgctttc caacgcatcg aacaacaggt gagcatctag ctgtctttca
    14341 acgcagtgca gaggcataga agccatgaca gcgttacctg aagcttcaat tccggagcaa
    14401 tcgatcaaca gctgaacgtc atgggggaca gccttctgga tagcccgttt tgatgcattt
    14461 gcgtggacct ttatccactc gacaggcgag accttcttcg aagacaagaa gtaggcttgt
    14521 gtgccctgtt tagctgtctc agtggcgaca atggcggcca gagactcctc aggttcgctc
    14581 aacagtaccg agccagcctg cttcgaaagg gtggcaatcg cacgggcaat taagtaagtg
    14641 gccaatacat tgagtgtggc tggctcgcag ttgtcactga ccgagacagc atgcttcgaa
    14701 tccacgtcca caatcgagct gtttgacttt gatacagcga gaacaaatga cgatgtatca
    14761 tcctggcgtt ggccatatac aacgtatatt cctttcccat ccatcgcggg aaggtgcaat
    14821 gcatacttga cttggatacg agttttcctt tcacccgctt gtaattctgc agtctggagc
    14881 atcatcttgg taggacccgc cactgcctca acagcgagat ctgtagcatc gacagttttc
    14941 gtgactacac gtcgagaagc gttgtaggtc tggttgagtg tctcatcggg aacgacacga
    15001 ggaataagga cttggccgtc agccatgatc tcaacctcgg gttcaatggc ccataacatc
    15061 tcacgagtgg tgtcggatgt ccctctaaga cgaaggaagg cttcgacaca gtgtcgagta
    15121 gcgatagcag gtgttgagcc ggcctcaaga ccaagaactt gaatctgcaa gtgttgcagc
    15181 tcagaaggaa cgatacgcgc aataccatgg aacatgcttg ctcggggtgc atgtgacttt
    15241 cctgccgttg ttacccacag caaggttttt gcactcatca tcaaattctg gatggttgac
    15301 attcgctcgg ctgtcatggg agtcgagaac agcggatcgt caagctcttg taaggaaatt
    15361 acctctgttc caggtttcaa ttcatttata tcaatgtcgt caatgctgcc agcgctgctg
    15421 atatgacgtt tccatgactt aggaagcaat ttattgatct cattgaccat tttggatgtc
    15481 aatagcttct tgccgccaat taccaaaatt gactccgttg gagccgacat gtccgcaaga
    15541 tttgatagag gctcgcgcaa gcgcaaaaag tcatcatcta cagcctgact cacaatcaat
    15601 gacgtgagat gcttgctttc ctcagctaga tcatggacga ccatgtcggc tcccgagtat
    15661 ccagtgtcat tcaaaacagt atcccagtcc atggcagtta ccacagggcc aagtttacgg
    15721 tgtggttctt cacttaacca ccatcccgaa aatccaccga aaatgaaagt ggtacgaaga
    15781 ctttccgggt tcgtgatctc catcaaaatc aggtaaccac cagggcggag tagagaccgc
    15841 gcattccgca aagttgtttc cagggaccga gtagcgtgga gaacattagc agccacgatg
    15901 acatcgtagg aattctcagc aaatccttgc tcggagggct gcttctctac gtccaaggtc
    15961 ttgaaaatca tcttgtgggc aaagtcagag aatttttcgg ctgctttggg gaagaatcca
    16021 gaggatatat cggtgaacgt gtaagagtcg tatgcgtcgt tgatgtcctt caaaatactc
    16081 caggtctaaa aataattagc aaaattcgtc aacggagtat cgtataacct accgtgccac
    16141 cggtacccgc accaatctcg agaatattgg cacgcgggaa cttgaaggaa atttgtttaa
    16201 cgaccttggc tatgtcattg ttgattcgag cagcacagtt gtccatatag aagcggttca
    16261 acatgtcgtc cttgctcatg acttcaagca actgggtctt ttcacggaca acgtcaggca
    16321 tattttcgcc acatgcgcgg agaagtttca agtcaatcga cgtaggatga attcgatcta
    16381 ggccatccat tatggaagaa tcatcgctaa gccactcgct ctttagcata ggatgacttc
    16441 cgctaccgac gttaaccaag tgttgctcaa atgcctcaaa catccgctgg tgataccact
    16501 ggaatttagt tcgctcttct ggtgagatct ccttcacaac gcgtttcatg tagaacaagg
    16561 ccatacgctc tgcagcctcg gcaagagaaa gaccttctgc gtctccgact gggtctcgct
    16621 ctggttcatc caagcccaaa gagccatcgc ttccccagac agttttagtg aagacaggtc
    16681 tgtcaccgga ggcatcctgc tctccaacca tcttggttgt aaggccttcg acttgcagga
    16741 acgtcttccc agaaaccttg tcgtaaatgt tcaagtctcc ggtcaacgag gacgcggttt
    16801 ggtggacaac ccagcagtca aagtcggctt taatttcatc actattctcg cgtgcatgca
    16861 gaatcggcac ggatgggctg acttgaatac gctcaatgtg agagggtagc aaggccgagg
    16921 tgattaaacg gctagcagga tgggcgcgcg cgatgaacaa ggtctggaat gcaacatcca
    16981 gcatggctgg gtgaaccagg tatttatcac tcaatgaacc ttcgggccaa atgccagtag
    17041 ccgcggaata ttgcagagta cgactgctct ccttgatgct acggaaaact ccggtgtagt
    17101 tgagaccaat gtccttgaac attccatacg cacggtcggt gttaatgttg accaggtttt
    17161 gaggaacggg gtctcgctgt ggtaagacgt cttccttggc ttcgccgaga tgaaccgaaa
    17221 gacgaccact gcaagtgtgg accattgtcc ctgtagactg atcattgcaa atatagtatg
    17281 agaagagtgc cttcagcact ttgtcggagg atgacccagg gagcaaacga gcggtgaaca
    17341 atgtctcaac accttccttg ttgtctggca cgaccacagg ccgttggatg tcaacatctt
    17401 caacttccaa taactcaatg gattttcctt tgctagtagc aatgtgctta ctggcttcaa
    17461 ctgcgatgga tacataggca gcaccaggca agagcacctc ttccaacacc tcatgtccac
    17521 ggagccacgg catctcactg agcttcagaa cattgcgcca acgtaattca aattcattat
    17581 catcgggggt acggcgtccc aaaagctcat gagtttggtc gcgacctgta cggtagcgct
    17641 ttgatatgcg cgactcccgc cagtagacct tgtcatggtc ccacgaatag ccgggtaggt
    17701 ctttgataac cttgggagtt ggaggctctg actcgtagaa ggtcttgcga tatccggcaa
    17761 agtcaacaaa agagggacct agttgcgacc aagtcacacc aatggcagtg gaaaaggctt
    17821 ctacgtcact agcacctcgt ttcaaaacac cagtatatag tgggactaca ccatatacag
    17881 ctttcagtgt ttgctctgtt ggtcctttca gagcagggtg aggcccaact tcaatcgcaa
    17941 ggtcccaagg accgccgtgc catatcgacg actcgacagc ctgagagaac aataccgttt
    18001 gaaccatgtt tgcgacccag taaggaccct tgagcgagct caagtcacct ttaagcagtc
    18061 ccgtgtcacc acgaacgcta gagttccaaa tgcactggcc tggcgtgggc ttgcgaactt
    18121 cgatatcgca ggccagtagc gatttcaggt acggctctgc gcatggtttc atgtggtgtg
    18181 agtggtaggc tgtatccacc ttgagctggc gtgcaaacac attttcttcg tcgagatatt
    18241 tcttgacttc ctcgattgcg tccaagtcac ccgacaatgt tacagtctgc ggggcgttgc
    18301 ttgccgcaac ttgcaaacgg ccgacaaatt cctcacggag gcaaagctgc ttagctttgt
    18361 ctaatgttag acctgcagcc agcatacctc cttgttggcc cttttctcct ttggccaatt
    18421 ttgcatgaaa gcctcggtag tacgcaattt gtatcgcagc ttggaggttt attatgccgg
    18481 atgcatatgt cgcggcaatt tcacctgacg agtggccgac aacagcatca aaattgagtc
    18541 cggatgcctt cagcatgttg accagaccga gttggacagc ggtgcataat ggttgggaaa
    18601 tggctgcctc cgcaactctg gacgaagaag cattggccat caactcctta accagcgacc
    18661 atttaggaat atcacttgaa ggaagtgctt gcaaggtggc atcgcaatcc tccaaagtgc
    18721 ggcgaaaaat aggtgatttt ccaatcagct ccttgcccat ttggggccac tgagcacctt
    18781 gaccagtgaa gacgcccaga attccgggaa cctccttggg gttgatgagt ttgggctgat
    18841 ggccaacctc ggtactaggt gtcttttcat tgttgttgac aaacttgatc atgctctcga
    18901 gaattgcatc ggacgatgtt cccgagaagt gggttcggac gcggtgggtt gatcgacgag
    18961 tctggagtag ccaactcaag tcacgaagat caaccgacgg gttttgatca aggtattgga
    19021 catatgcttg cacggtatga agcagtgaag ccccggaacc agcagagaaa agaaggggtc
    19081 ccagcgcacc ttcctcgcac ttctcactgt cagaagatgg agtcgagctc tcaaagcttt
    19141 caataattac atgtgcgttc gtgcccccaa atccaaagct gttgacactg gcgcggatgg
    19201 gggtgttctc tggcagttcg ggccacggca tagctttttt ggggatctga agagggccat
    19261 aaaacggtgc gatggctgga ttgagttcat tgaatagcat gttcggagga attgtacggt
    19321 tcttcagggc gagaataacc ttcataacac ctgccagtcc agcacaacct tccaggtgtc
    19381 caattatagt tttgatggat ccaacgtaaa ttgggttgtc tgctgacggt tcaaatgctt
    19441 cgctgatggc tcgagcttca acagggtcgc cagctggtgt tccagttccg tggcactcaa
    19501 agtactgggg tcggtctttc accggatcaa gaccagcacg acggtatgtt tgacggatta
    19561 gggcggcctg ggttggagca aaaggcatgg tgataccggg actttggcca tctgagttta
    19621 caccggtggc gcgaattacg ccttcgatat gatctccgtc cctcagggcc cgactaaggg
    19681 gcttgagaag aagcgctgca gcgccctctc cgcgggcata tccattcgcc gatttatccc
    19741 acatccgaga ctgcgagtcc ggggacaaca tgtgaagttt ggactcggca atgtaagacg
    19801 cagcatcgta aataagattg acaccagcga cgaccgcagt ttcacagtct ccattcagca
    19861 ggccacgggc tgcgtggtgg agtgccacca aggagctgga acaggccgta tcgatggtct
    19921 ccgatggacc cttaagatca aaaacatagg aaatcctatt cgagacgata ctgttggcag
    19981 taccggtggc gttgtatttg gctattgttt ccaaatcccg caattggata ccagcgtaat
    20041 cattggtcat ggtaccaacg tggactgcag tcagggaacc tctcagttgc tccagagtca
    20101 ttccggctga ctcaaaggcc tcgtatactg tttccaatag gatacgttgt tgagggtcca
    20161 ttcctgcagc ttcggcaggg ttgatggtaa agaaagaggc atcgaagagc cgactatcct
    20221 cttcgagaag gtatgacttg tttgtgacgt ccgtcgagcc atgtgtatcg ccgtctgggt
    20281 gatagaagcg tttgaggtta aggcgatcgg ggtcgaattc tttcagcaca tcgcggggtt
    20341 gtcggagaag atcccacagc ttcgaggggg agttggatga acctgggaat ctgcatgatg
    20401 aacctacgat ggcgaccggc tcttcgggca gttgaggttt ggtttggttg ttcgaatcgt
    20461 ttgccgccat gttgactaac aggcaagact ttgcaggttg tgggtatgta caatgagaaa
    20521 taagtctgta aaatggaggg tatcaaagag agatgcagga tggtcaagag agaaagtaag
    20581 ttgaaattgt tcaacggtct gcagaggtgg atagagtgag acgagagtgt ggcaagtgat
    20641 ctagtatggt ctcagaaggt aaggagagaa gctctctgta attcaccgag ccaatattct
    20701 attttgtggc tgcggttttg ctcaaaaact ttcaaatagg ttgccccaag cgtgagttct
    20761 gtattggctt ctatgtgcat ttacttttat acagctacta cggagaacat gccggtcacc
    20821 ctgggcatgt ttagtccttg gcccctatca ccccatcact aaaccagata tgatcaacgg
    20881 aaatataaca gggaggaata ttccgatgtt tctagcaaaa tgactaagcc tggcgtactt
    20941 cgtgaaggcc ataatgatac gatatctgca aaggcgtggc ccataagcac cgactcttct
    21001 ccacgaggca atcacatcaa tacgaaacgg ctccctagtg gaccccaagg tatagcagcg
    21061 tctgtatatt ttagagtcga cgccagcgaa gtctaattat taaagtctcc aagcccacgt
    21121 gtggagaggt gtaagcaccg tacgaagtac tccgtagtat gggccggcgg ggaatccttg
    21181 tggatcatcg gcacggacta acaagaacta catccacttt ttgcacaaac agtataatgc
    21241 tgaaagcttt cggccgtatc attggggtta tcttagtcag tttcaagcca agtatggatt
    21301 aatagtttaa tacggactat gttacgggtc cccaggccca cctgtctgac gactatgcac
    21361 ggattattca aaccggagaa ttctaaggtt cgcgcgtcag atcgtacgga atattccaca
    21421 gatctctcat cacaccccgg ctgcttcagc ccccagctgt tgatatgaga tccactcaac
    21481 tgagtatgca tggcatcatg gtggacggcg ccaaaactca caggtttcag cagcgtcagc
    21541 aatctatcga ggaggtcata tacgcgtagt ggagagactc agattattcc gggcccggcc
    21601 gttttctagg agccaccgac ttagacactc ttaactcttc gcactggtgt gatttcgatt
    21661 tgttctttcg tttctcaatt catttttcga cgaattgaac atcacttcaa tatgatcact
    21721 ctacagaatc tcccgtggat ccttctctat acggggttcc ttgctatttt cctcagcaga
    21781 ctatttagca atggcaagca gtctcgcgac gaaaaagcca atggatgcca gcctcctgct
    21841 cgataccctc agtgggaccc tatcatgggc ttggatttgg tctacagtca agtaagcgcg
    21901 ctgaagaaca accgatacct cgaatggctg cgcgatctcc atgccaaaat gccaaagacc
    21961 ttttccctta acttctttgg tcaacgatgg atttacagta tcgagcctga gattctcaag
    22021 gctgtgtatg cgaccaactt cagagatttt ggagttgagc caatccgccg tcacagtaaa
    22081 ggatccatgc cgtttgccga caaaggagtg aacaccaccg atggtgaaga ctgggaattt
    22141 agccgcttgt tgatcaagcc gttttttgag cgcaatgtgt ataccgacac tgatcggatc
    22201 aaagtgcacg ctgaccactt cctgtctctc attccggctg atggtgaaac tttcgatgcc
    22261 caaccactgg ttcagcgctg ggtaattact ttaaatgcca atgttcgatt tattgctgac
    22321 agcatgggcc tagtttcttg acttaacgac cgagtttatc tttggagagt ccatgggctc
    22381 tttagctcat ccggaacgtg ctgatatcgc ctggaccatg ctggatgttc ttcggggtgg
    22441 ccgtctacgc gcacagatgc atcgcttcat gtgggctcgt gactggacct ggtggcttaa
    22501 ggctgtgtat aaagtgcacg actatgtcaa cccatacatc aggagcactc taaaagaact
    22561 tgcagagcgt gaggagcgta tcaaacaagg cttgcccgta ggacccgagc gaactgatct
    22621 cgtgtggtcg atggcgactc atcttcggga cgaagaacta ttgcgatctc agctctgctt
    22681 gatcattgtc cccaataacg atactacctc tatctttatt agcaattgcc tgtggcatct
    22741 ggctcgtcac ccggaagtct ggaagaaact ccgcgaagaa gtctttgccc tgggtgaaga
    22801 gacgccgctc acttttgaga ttttgcgtaa tatgaaatat ctaaatggag tactcaatga
    22861 aagtaagtta tcttatgggt cttatttagg tttttttttt ctcttttact aaatttacag
    22921 ctcaccgtgt tattcccaac aatgttaccc aggttcgtgc ctgtgtgcaa gacacagtcc
    22981 tgcctgtggg tggcggccct gatggaaagt ggcctgtcca agtgcgcaag ggagacatcg
    23041 tgtcagtcac caagaccgtc atgtaccgtg atcctgacta ctggggatca gatgctgacg
    23101 agttccggcc cgaacgattt gatggtctcc gaggcacctg gaatttcttg ccctttggcg
    23161 gcggtcctcg tcgttgccca gcgcagatga tgtctcagac tgaagccgca tacatgttgt
    23221 gtcgccttgc ccgtacctat tcccgcatag aagcccgtga ccctgagccg tacactgcag
    23281 tcatgcgtat tggcccatcc aataagactg gcgttaagat tgctttgtat aaatagagcg
    23341 actgacggga ttgaacatgt accctacttc agtttgtatt gtatgaccat ctttacttga
    23401 gatttactgt ggtatcatgt acaggtcccc gttacctatg agaatcgttc cgtgttggtt
    23461 ttaaatgcag tcgatttttt ttcggttacg gattacgatg tgatatgcaa ttgctatttt
    23521 tgatcggatt tctgaaattt ctgtgactac ttgccgctac gcgttatgaa ggaaagttgt
    23581 gcatgcaatc aggggatggg cttttgtttc tattcgattt caactagcgc ctgatcaaga
    23641 aatagaggct tttggagtgg gaaatattga aatcgaataa gacgagaaat cattaaattt
    23701 gatactctat atgaacgaat gaacattaag aataggccat cacatagcag gtcccattcc
    23761 tcacaagtat ttcctcgtct tgtccacgac atgctgcgca aaaacgcccg gatgcgagac
    23821 atacggaaga tgcgtgcccg gaagagtacc gatatcaaca ccgatcttgg tcgccgtcac
    23881 aatattatcc atgaatacgt gtgtcaaact cgacgcaccc acagtccaat ccagcggccg
    23941 ttgtttcgtc gggtcctcca gcagccgggc caccggcgtt gaatgcggga tggtgtttgg
    24001 ataccctcgc gcccatcgaa tatagttctg gcgcagtctt gcatgggcct cgtcgcctag
    24061 cgcgtcccag gccacgggat caccggaaag atactcacgc atcataccgg actgtgtctt
    24121 aatgagcgtc tcgtcgtcca tcttgcccag tgccaaaagc tcatctgcct gtgccgtcgg
    24181 cgcctcatgg gctatgacat ttctcactcg ctccgggtag tcgagcagca gcgtcaacac
    24241 cgtggaagcg cccgagctgc agccgaaaaa gctcacttta cccacaattt tgagtgcgtc
    24301 tagcacgcca atcacgtatt tggcgagctt ctgcgccgtg accgcttcgt aggtttccgc
    24361 cggcgcattg gttgaccgtg acatccccgg catgtcgaag gttgtaacgc ggaagccctg
    24421 cgcggcgata agcgacatag gcttagagta catctcgcac tctcccaggc cgtcgggcac
    24481 gaggatgatg tctggaccgg agccttcttg ctcgtagtac cagttgatgc cgtccggcgt
    24541 ggtgattgta gattttgtcc gcatgatatc aatgatattc gatatatgtc caaattactc
    24601 gattgtcctg agatgtattc aaggcagaaa agtagttgca gcggatgcca gatttatgtt
    24661 gtgaggagtc ggaatacgca tcaattgatc accccggtcc cgctacgttg cctatcttct
    24721 aacgcagatc attttcccca tggtaaatat aggcttcaag gccttatatc tcgctcgcca
    24781 tcaccaaatc aataaaaatt tgcattttaa tctattacag gagaacaaat aatcgcatgg
    24841 aatattccaa gataaaattt cattaaaaaa ttggtttaag aacaagcaaa ctcttaataa
    24901 atttttatga catgtggcgg gacctatgct caaaccttgt cccggttccc accggcttga
    24961 cgctcccggt atacatcacg agtcagaaca ttatccctat atattttact tgatccgatt
    25021 ggcactgaac acgccaacag tgaactatgt cccctcatag ttgtctccgc gtttgtgggg
    25081 aaaatccggg gtgtctcgcg accactttgt atctccaccg gatcgaaatg tgctgtcacc
    25141 gcagatacag gaatatcagg tatacatatg tttaagacta gcatcaaaac taggtagaca
    25201 aatcaaccgc ccggtctact ttgcatgttt cggcgtatgt cgtgggtctg ctagtgctcg
    25261 gtagcgagat acatattcat gataagattt tgaagacatc aacgttagtc aacatgaccg
    25321 tggaggatgc gtatgtcagc tctctcgcaa attaactctt ctcttactcc acatcaattc
    25381 acacatataa tattcactaa ctaatagagt ccctatcaat tacttagcac aacatcaagt
    25441 tatgcacatg taaacgggac gtcccgccgg cccgcagcgt cccgcaagtg gcttgtatcc
    25501 cacaatatgc tcgtaattcc tcgttctggt cctattattt tacgctggag ttagagacat
    25561 tgtctttagt agttgctagt tatccacggg gatatttcgg gtttctgttt tgtggtcaaa
    25621 actccaacat aaaataaact cccaccacac gcgacgcgaa agcacaatgt agccgagctg
    25681 ccagagcacg aatttcaagg attctcacac attctaaatt ccaaaattgg acgctcgcat
    25741 cgacacgcat cgacacgcat tcccactttc tgccgccctt ttatcgggag gcatttgtgc
    25801 aatgttgttg tgaggattcc cgagagaata tccctgtcgg tggacctgct tgataccaca
    25861 tgtgcagtga aatatattat tcccattagc ccaaggagac tatgaaccta acgagattta
    25921 tcaatttaaa tacaaattca atgcatctgt aggaacttga aggggtcata attgagttgt
    25981 atgcatgatc ctaacgttcg aacttcaaat tgcccaaatg ccaataccgg ttttcgcagg
    26041 aagccggata ccgttcagtt acgttgctgc aacgtttctt gagttgaaac gtgtcgcatt
    26101 aagatacaca tacataacca ttgcaaatgt cgatacgtat ataattttat tagcgtggca
    26161 acatcctgcc acgtatcagg aatatggtac cgttgcaaaa tatgaacggt tgccaaacgc
    26221 ttgcaagttg caacccgctg ccagttgcag aatcttgata agttacagaa ataaattaca
    26281 attcacataa aaattacttg tattattggt attctaatta caagttggga aaccgcagtg
    26341 aggcctgcac caaggcctgc gcgcaccgat ttgaccgaat tgagaagcct gcaggccggt
    26401 tagtgaggcc ttataaagcg gatttgcagg cataatctat gcagatcctt cctgcttgcg
    26461 tcccttggca tgcagttcct caactggcgc atcgacgtga taatccatcg tcttcttcaa
    26521 atcgcctaag aaatagcata taatacaggc gagcgctccg aatggagctg ctattatata
    26581 cacaactcgc aatccatcgg catatgcctc cttcaaggca ctggctcctg cgctgatgat
    26641 cgcaggcgtc acgccgggga tcgctgcaag ggctgcgcta tctccgcctg agagggcttc
    26701 gatgaatgac ggaagcgagg tggccgggag cccagcttca gttgctgctg cggtaatgta
    26761 actcgggata taagttgtca gacgcgtggt catagcagcg gaataaatcg ccgtaaaggt
    26821 cgtggcagca acggccctgg cgcttgtcgt cgccgctgtg gccgtagcaa tgagcttatg
    26881 cggcgtcgag agctgtacgc ccgttacaat caagacgagt ggtgcgccga agccgatacc
    26941 agccagcccg gggaatatga ctgatgatag gttgtcagag ggattgattg tcgtcagtcc
    27001 gattatgcca ctggtgaaaa tcaggaagcc gacgaataat ggcaatcgga tcaagcgcaa
    27061 ctttgtactg gcgtacccgt acaacacggt ggtgaagccg gaggcgatcc agaagggcat
    27121 ttgacgcgct gttcctttga ttgggtcggt ttcgaacagg atagtagtcc ttcagatgct
    27181 gttagttcga tagctgactc aacacaagcg agtttatgct tacaggactg gataatacgg
    27241 gatgaaggaa aacaacataa ctccttcgat gaacataagc atgatacaca gcgtaaacgt
    27301 gcgtcctctg tccttccccc cgtggaaaag gccgtggtgc aaaatgcccg ttcgtgtgcc
    27361 tttccactcg tacatgccga acagcacgag cacggccatt ccgatgacca atgttgtcag
    27421 caccggtgca gtagtccacg catacagacc tccgcctaga ttcagtccaa cgagcaagag
    27481 cgtcaaacca gtagtgagca gccctactcc gggaaggtcg aggcgcgcca ctttctgcca
    27541 gatggagagg tggtcgaggg tggtgtgtcg ttttggtggg cgatacccga tgagcaagct
    27601 gatggcagag atactccaca gagccatttg gatccactgt cgaaagtcag atagatgacg
    27661 cttgtatcat aggaaggact cacataaaaa ttgcgccatc cagtatgggc attgttctta
    27721 gttagaccgc cgataatcaa cgggccagag acggcgccta gagcagctgc gacgttcatg
    27781 aacgcctgtg ccactatcgt cacctacatt agcaatactc ttgaaataaa cccaagcatt
    27841 ggtcaatcat actcggccgc catttcctcg gtaagatctc gctcggaacc gcatatgcca
    27901 ggggaatggt ggaaaatcca aagcctatga gtacttgcgc cgcaatacct ctataaatat
    27961 cagtcgaacc gggcgcgata gcggcgccaa tgacggatat cgtcgaagca ccaaccagaa
    28021 gagtctttcg cgcctggaat atgtcggatg cagaggagat gacgggcgaa agcacggcct
    28081 gcacgaggga cagcgcgttc gggatccaag tttggcgctc gctgttgttg agatctttgc
    28141 caatgtatgt caactgccga gtcgtgtcag cttcatcgac cggcctacta ccgcacatca
    28201 atgcaaatgc gtatcatatg cacgtaccac ggctggcggt ccctgtagag ccagcacctg
    28261 caccaggttc aagaagaaca tggccaccaa agccagccac gtgcgggcgt ggaactgcgg
    28321 ctcttcatcg tcatcgtcgt agactggatt atcaagccga ctctccgtct gttcaatatg
    28381 cgttgctcct gtcaccatct tctcgccaga gctcggtgta tcggggcttt cggttggcat
    28441 tgcgttctag atatgaaatc aacaatcatc aactgtcttt tgtcagatta tttttcttca
    28501 acaggaccta gagatgcttc agtctatctt ttatttctct ccccagtaag catgatacgc
    28561 gccatgtttg ggtctgtgca atggtcccgc cgacctggtc tctgctcggg tctcgacttg
    28621 cggggaatcc caccggatat ctgcttcatc cagtgacatt cattgttcgc ccagggcttc
    28681 cccaggaaat cgagaggttt ccggggtctg ggatgaagtt aattttgatg ttttgcgttc
    28741 tggattccga agtcacccta acatgtaaaa tttgaagttc actggtgcca tctgcaccaa
    28801 ttgatagttc aaggttattg gcatatgtag atgtaggcat gtatcaatta agaaaaaaat
    28861 tcaagttgac ataatatagc gttacagcag gtgagaagct acacgctaac ttgaacaaat
    28921 tccgcgctat tcccatgcct ttagaatagt atcacccttc tccaaccggg cgtatactaa
    28981 actgtcatgc caaagtgttc tcgacttttc ggcatctttg gcttcaggcc caacatcagc
    29041 gatctcagac ccattcaaat atataccatt cgggtggtcg cccagggtgg cggtgtcaaa
    29101 agcagcgcgc actacgtctc tggcagactt ggttgttgtt ctaatagtcc cattgggctg
    29161 tagccataca gccagtggtg ccagcaaggg taaaacaaat ttcatcaata gaaacatgac
    29221 ccagatgctg cgacgattca gttcactggg catggcgccc ggatcaaccg ctacaactga
    29281 tattgcagaa agttctgggt ctttttcaat ccggtttgaa agctcacgac tataattggt
    29341 taatttcagg agttattttg tcttttgaat tttttctact aggaggaaat ggttagagta
    29401 cttacaacat catgatctcg catagttttg cagcgccata tcgtcgcagc ccggcattta
    29461 agtcacccgg gtgttctctt tcagagctcc actttccttt cgcaagatcc tcagtattaa
    29521 ttggatagtt gaagatttgc tgatatcttt ttggtgtata catggatgct gatgggcctt
    29581 ttttattatt tggatcagtg gtgctacagg ttgacacacc tggtattagc ttgggtctgt
    29641 atgtgaggct gacagtagtt tttataagaa atttgaaggg aaaattacat actcatgcgt
    29701 ccaactaccc agtacttcaa tccggccatg tttcttatcc atgctctgca atagaagcaa
    29761 tgttaggaga aagtgggaca ggtaattcac ctggaacgac atatcgaaac cgtcgttggt
    29821 aaaagagtgg gtggtctgct ccccccaccc ggcgttcaag atcaacgccc gtataggagg
    29881 gatagtgcca ttggcaacgc gactattgat gtctcttgca gcccttcgta cgctatcaag
    29941 agaaccaaga tctatcgcca aaagctcgtg actgtgtttc acggacttgg cccattcaag
    30001 ggtacgaagc actgttctcg ctcctcgcac cgtgtcacgc acagtgtaaa taccataata
    30061 attggtattc aagtcttgcc ggtcgagaat atggcttaca atggcgtttc ccaggcctcc
    30121 gttggcacca gtaacaataa ccgtcccctg ttgattcatt atatggaaac ttgtttgctg
    30181 tatgtcggtc tgagatttaa tcgcgtgtaa gccgttgtcg gttattggca ccaagtgtct
    30241 ccatgtggcg tcccgctttc ttcgaagagc actcggccca atgtaaatta ttgttatgga
    30301 aggggaaacc gccccagcgt caactattag tgctgaaact agtagcttac ctgcccggaa
    30361 tattcgtgtg tcgggccaat cccagtatta cccgctatac tccgcgaatg gatcgaagat
    30421 agtgacctaa ggaacatgaa aaaatgttat ttattttaac atcctacaca ttcacagtaa
    30481 taatagtagt gaaactaccc tccagtgcca acacgagagg caacaggcaa tcgcatacaa
    30541 cgacctgtcg tggagcaagt ctcgtgtcgc tcggagaatt cgacccaccc ccgaccaaga
    30601 aatacagaaa agagtaaacc acacaggaca gcgacaacga caacgctttt gctatggctg
    30661 accttcatct ggcaaaatcg attacactcc gatgcggtct cacgctgcca aaccggctgg
    30721 ctaagaccgc cattgccgag agtatcgccc ctcggaatat gcttattgac gaaggatttc
    30781 accgtgttta cgcgccatgg gctgaaggag gatggggaat ggtcttgaca ggtatgtacc
    30841 gaaacatcac actagcgctt ttctaagaaa gaaagaaaag ggaaaaaaaa aaaaaaaaaa
    30901 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaatcta aaaaaaaaaa
    30961 aaaaaaaaaa aaaaaaaaaa cactaccccc acctggtgga agctgacgcc gagtaggcca
    31021 tgtgcaagtt gattctatgc accttggcac ccataccgat ccagcggtaa acgcagattt
    31081 cagcgacgat cagatcgtgg gatcctggaa agtctgggcc gccgtatgca ataggcatgg
    31141 aactccaact attatgcaac tcaaccaccc gggtcgccag gcacctattg gggctggcac
    31201 aagcggggtg tttgcgaaaa acatatccgc aagcgctgtg ccaatggaca ttggttcagg
    31261 actgctagcg cgagcagtga gcaagattgt atttgggaca cctcgtgaga tgacggtaga
    31321 tgacattggg aagctcgttc gacaatttgc tcgtgccgca cgtctggcct cccagagcgg
    31381 gttcgcgggc gtggaattgc atgcatctca tggatacctg ctggcccagt tcctgtcagc
    31441 agcgaccaat cgacgtaagg atgcatacgg tggaacaccg gccaacaggg ctaggatcgt
    31501 ggttgaaatc atcaaggcgg tccgggcaga agtgcctgct agtttctgtg tcggtattat
    31561 actaaccgca gtccacggct cagcatcaac tgaggaattt caatctttta ttgagcaagc
    31621 tcagttgatc tgtgacgccg gtgtcgattt tatcgagatt agtggaggaa cattcgagac
    31681 cccttccgta aggagcccgg aaaaccccta atgtgaacga gttcatatct aactggtttt
    31741 ataaaaagat gttcattggc ccagagaaac gtggaaaagc ttatgactgg gacaatcaag
    31801 aagccttctt cctcgatttc gctcaggcta ttcggccgca tcttgggacc gtcccacttc
    31861 tcttgaccgg tggctttcga agctgccatg ctatggaggc tgccgtcaag agaggtgact
    31921 gtgacatgat tgggttagca agaccagcgg ttgttaaccc cttactgccc aagacagttg
    31981 tcttcaaccc agaggtcaat aagagcggag acacaaagct acatgccacc cgtacaccag
    32041 caccttggta tatcaagttg tttggaataa cagcgttgaa tgtgcatatg gacaatgtaa
    32101 gtttaatttg gataaagact tacacccgca cccgcaccca ctggtctaat tcattcatag
    32161 gcatggtacg tcggtcgact gcagacgcta gccaaaactg ggcgttgagg aataaaaact
    32221 tgaatggaga ggatatatca ttgatacaga tagaaacaca tgaaataaat tatcaaatta
    32281 gtagtaggca cgcgcagctt actgtactca tcattatccc aacaggttaa taatctcaat
    32341 aaaaaccatg atcatttata tcctttcgta atacagagtt gactaaatct aaggtcaaaa
    32401 cttaaatata ttaatgagtt gatagcaccc aaccaaagaa cactacaact atttagattc
    32461 agtttaaggt ttccttccag taacgaccat gaacctccag cggtcgtatc caacatagcc
    32521 cgcagtacca gctagcatgc tgacaaaatg cttctcgatc cccaatagcc tgacgaagag
    32581 gtatggcact agcaagacaa cataaaacat ccgtacaaca ggtaagatat tgtcagaaat
    32641 atcacgggat tcgatgtcaa caaacccagc ttcttcgaga aggcccttgt agaaaccgtc
    32701 gtgggaccgc tcgtttgtcg gcataccagt gccgacgttg atcatactta actgttccgt
    32761 aagtctcgga tttttcttgt cggcttcggc attggggcga cgttctactt cgactagggc
    32821 aaagcgaccg ccgggtttga ggacacggaa gaaaccagcc aaagccttct ctgcagaaaa
    32881 tgcatggcct aaagactgca tggtaaaagc gccgtcatgc gatgcactgg ggatggcttc
    32941 tagacgctcg aagtccatct tctctatgac aatctggtcc ttgggcagat ttgctttctg
    33001 ggcacttctt cgggcttgct cgacgtgatg gtcaatgata tcaacgcctg tgacgcgcat
    33061 accgtgcttt gccaggtaca aggcaacatg accaacgcca cacccggcct ccagaatgcg
    33121 agatcctgca ggcaaagcta gccagcccat caatttctct tccatgctat gaaatagtca
    33181 acaagagtgg cccaatgatt atgctcgagt tacaagaagg gtgactccat accgacggag
    33241 ggacttgtca ataggaaatg gagaccaagt tcctggagta tagtacccaa aatgctgggt
    33301 gccaccgaac accaactcgt agcccatgcg cgattcttgc gactcatagt atgtcttgat
    33361 cgcgcgctgg gcggcctctt ccgacgtgaa gacttctgac gatgccatta tgcctatgat
    33421 cggcctctat tgtctatgta tttttctttt tgatgtgtct cttgtctctc tgctttgcag
    33481 atttcaacat cgttccgcac ttagggccag agcatataac taaccagggg actgtttggc
    33541 taagattgtg ggggccgacc gcctgtagtc agggcatagc gtggcccata gcgcctacgg
    33601 aatacgtagt taatggtgga cacccccggt ggaccatggc atgctgctcc ctccccggag
    33661 tatttacagg ggccacggaa tattatgggg ctgctggatt ggtttccaaa cgaaaagaaa
    33721 atgagtgcat catcgatgca atgcttactc ttccgagaga tcctctcaat ggccattgct
    33781 cctgttagct gacagtctta aactcgcaca aagctgattt ccaggcttgc aggacccatt
    33841 gctgcgaagt gaattgtcta caattttcca atgctgcgtt gaaccaagat ggcgccctta
    33901 gcaacttatt tgtcgcaaat cgacgattac ccgaaatggg ctctttttac tggtggctct
    33961 attgtgcttt tttttctcta tcggattttc ctatcgcctc caagctaccc tccaggcgtt
    34021 cccttgatcg ctgagcctgc aggacgaaca tggttcagtc cgaaaaccag atggcgctac
    34081 tacactgatt gcgcatcgct ctatctagaa gcctataatc aggtaggtta atgacaacag
    34141 caaggagaaa tctttgagat ctgactccag cagtactcta aaaagggcaa accggtggtt
    34201 gtgcccgggt tcggacttgg gtatgagctg atcatgccag agagccttat gtcttgggta
    34261 atggcacaac cggatagtgc catcagtgtg aaccaggctt tcctcgacat caacaagacc
    34321 aagtacagtc tcggccacac aagatactgg ggcgatactt ggcaatttgt gcttgtaaag
    34381 acccagctaa acagcgtgct ccaatacttg atccccggac tcaacgatga actcaaactc
    34441 gcgttcgatg cccatttcgg cacagataca gaaaactgga aagaaattga gctggagaag
    34501 gtacttaaaa acgtgatcgc gcaggccgcc agccgattca ttgtcggtgc gcctttgtgt
    34561 cgcaatgaga aatacttaaa agcaaactat ggggtcattg agggtatgat gctcaacgca
    34621 atcttcacca actccagccc taagtggctg caaccaatta tcggtccttt ggtatccaag
    34681 aaatccatca ataactgcga aatcgtcaaa aaagagttcg agccgctttt ccgggagcga
    34741 ctggaaacgt tgaaacacga caaagatgat cctaactttg aagagccgca ggatcacctg
    34801 caacttctac tgcgctacgc tgtcaaggag cgcaaggatg agcttaatga tctggatatc
    34861 atcgctaaac ggattatcgc ggtcaacttt gctagcatga accaaacaac tatgactgtg
    34921 gtaaacatgc tactgaatat tcttggttct gacgccgagt tcaacacgat cgccgtcttg
    34981 cgtgacgaaa tgaagagaac aacatcagat ggagagccct ggaccaaggc taagctcgcg
    35041 acaatgattc gcacagacag tgtggtacgc gaaacattgc gtataaaccc gttcggaaac
    35101 cgtagtttga tgcgtaaagt catcaaagaa ggactagtta cgccagatgg catgaaactt
    35161 cccaagaact ctctgttttc attcttttct gaacccgttc agcatgatcc cgataagttt
    35221 gaggatcctt tcaagtacga ccctttcaga acttcacgtg agcgtgaggc tgctgccgat
    35281 gaagaaggaa aaccaggcgg ccatgctctg actgttgtgt cgacatcgcc caactatctt
    35341 ccgtggggcc acggaaaaca tgcatgccct ggacggttcc ttgtcgactg cgagatgaaa
    35401 atgcttctca cgtacgtgtt gagtaattat gacatcgaat tccctgtcga gtacaatggt
    35461 cagcgaccac cgactatctg gttggcagag gtcggcttgc cccctcgcgg tgctaagatt
    35521 cgcgtgaagc gtcgcaagga ggctatataa actcgaatat ccctcatctc tttagctaaa
    35581 gacaccaaac acagttctac tgtcgttgag atgaaaaaaa tttgacgaca ttgactgttt
    35641 ctattttttc cctcaatttc ttgtttcttc agaaggcgtg gtattctagt aaactcgaac
    35701 cctatctttt aaattgaaca aagaattttg atggaagtgt ataaggaaat gatttctggt
    35761 cattaaactt tctaattcaa cgaatttaca aactatttaa ttcaaaatgc gtagttcctg
    35821 ctacatagcg ggacttgatc ataggaagtt tcataactct tcactgttaa ctacatacgg
    35881 ggatgagctt ggtttctttt ttggaacacg ctacaatctc aatatttata tcccatggca
    35941 gtggtaggtg gcattgaaac aggtggcatg attgtattca tgggaggtat ttacaatatt
    36001 cacttaacga atttccaact gcttagtagg gctccgctgc tcaactaatt catggcaacc
    36061 cttcgtatac gcagacacat ctatacgaat aacaagaagc aacagtgagt aacaaaatag
    36121 caaacaaaac actaagcagc ggcacaaagc tcgttggaaa taggataaac tagcttttta
    36181 cccttgatct gtcctctcct tacagcttcc ataccctccc caatggcggc aagtccacct
    36241 agtctctcct cctttggatg tggggtgatg agcccctggt caataagctt ctgagcgacg
    36301 acataccaag cctcagcagt gagtaggtct tcagggcggg cctccaggtt atatggagct
    36361 gcccaagcaa ttgggtggcc gaattggcta tatgtgcaga cccagtcggg gacaacgctg
    36421 cggcgcgtgt gggcgcgaag tggaaagctg tccagggcga cgtaccgacc accagatgag
    36481 cccaaggctt catagcagat gttcattgac gctgtatcgg tgatacagtc aagagccaat
    36541 gtcagggtat ctccagtgtg ttcacggagc tcagcgccgc aagttggcga acgatagtcg
    36601 aatgtagccg tggctccaag ctctgtggca tgtccagctg atgccgagga acaagtggta
    36661 attggtcgga agccagctat ctttagaact tggatagcca tggcgccagt agctgtgcct
    36721 ccaccatata ccaacacaaa tgggccatta tcagggcttg ctgtgcttgt ggtagtaggc
    36781 attggcagtt gcatgtactg gaagagagat aacccaacag ttgcaacagc tgcacctaat
    36841 gttgaagcag ttgaaaaatc cataccaccc gggatatgcc agacgagtcg cgccgggaca
    36901 gcaacatact ctgcgaacgc accattgtcc cgacgcaaag ggttatttcc aaacacgccg
    36961 ccaaaaacac gatcaccaat ttgcactggc ttcatgccgt tggtggacct aaacgactcc
    37021 ttggggacat cgctccctat tgccaccaca acaccggaaa agtcagtgcc gctggttgcg
    37081 cctggagagg gggacatgtc ggccgacttt gcgtcgacat ggttgattga gatgcatgcc
    37141 acgcgtacaa gaatgtctaa tggttgaatg actggcagtg cagtgttttc ggacacagaa
    37201 acattgttgg gcccaagaat cttgagcgcc gtgtgtatag atggtagggt cgcatccatg
    37261 gtgaatttgg tcaagaactc tcaaatgccc caagtagact aaagatttat ggctctaaga
    37321 gagctggaag atagccactt aatgaatgag gtcaaagctg taggtaatag tcgtcacgga
    37381 tgatggtatt ggcctttggt acaaattgga cttgatgata tgtatgagaa cgtgtccaag
    37441 acaaccaaaa gccgacagag gacgcgtaca acacagtgag agcctgatgt aatgtagaaa
    37501 cccacgtgct tcaaacaaat ctcacggctt catttggggt tttacttggc ggattggtat
    37561 cttccactac gggcatgaac ggcaaattag gtgcgcgtga gtgtgtgaca ttgacctctc
    37621 tacttcgtac ttttctctgg gcccccgaaa gaacattatt ccagaagcgg gttattatgg
    37681 atcatggatt tccatcggag atttcgagct tgattacgga tgatcgacta atattccgca
    37741 gcatgtggtc actcttgcgc ttaattgggc gatcgctcta gcggttgctg gtatggtggg
    37801 ggcgccgcat ggccgggtta ttgtggggcc gccaagcttc cgcctagaaa taaccttaat
    37861 cgttgacggt ggtaaattac cgcaaaatca gctgctacgt acgtactact actagcctgg
    37921 gggccatccg gggtattaca tgcgcaggaa gcttggactt caaacttccc gatacttttt
    37981 cgaaaaagta ttagagaacg gaattttgat agacggacga taacatcagc gtagggggcc
    38041 gcgttgcttg tgtattccgg cgtagttctg tctcacctta caagccggca caactttctg
    38101 tgtcttagcg gtttcgaatt gcgaacagtc aggcacactg cgaccccgtt gacttgctgg
    38161 gctctatctt gagatacctg acacgatatt gatttggccc attcttgtca aacaataggc
    38221 cccatgtatg tactacatca gcgtgcttat caaacctaac tactaatatg taagtgattt
    38281 atgagaagcg tttctttatt tgtccgtctt gtgtttttgg atatgtttga gggctatcat
    38341 acattccaag tgacatttat taagtaatgg atctcaacct tgccaagcca atcaccctta
    38401 gatgtggcat tactctccct aaccgcctgt ggaaggcggc tatgacggaa gaatttgcag
    38461 acaaacgacg tcttccgggt agcgaagcat gtctagccac atatcgtgta tgggcaaatg
    38521 gaggctgggg cttggtaatg accggtaagc atcacgtgag ccagcttcca tccgcaaaga
    38581 caatcaagtt gctttgttgt atcaaaagta tattaaactg actgtgacaa ggcaatgttg
    38641 atgttgaccc cgcgtatttg ggtagcccag ggaatattgc tgttgacagc tcaataccaa
    38701 gagaaaaaac tctggccgct tggagagcct gggctgaagc ttgctcacaa aatggtgcaa
    38761 aggcaatagt ccaaattaac catccaggtc gccaggcatc gttcaccaaa agtatagcac
    38821 cgagtgccgt gcccctgaat ttagggccag gtatcctgcc ttggatgttg cgctccctca
    38881 tatacggcac acccagagaa atgacagtgg acgaaattca cgatgtaatc atgaaatttg
    38941 cggaaactgc acgtctagcc gctgatgctg gatttgccgg cgttgagatc cacgccgctc
    39001 acggctacct tttagcccag tttctgtctg cagcatcaaa caagcgaaca gatgcatatg
    39061 gaggttctgc aaaagctagg gctaagatcg tcattgatat tattcacgct atccgctcag
    39121 atgtaccgaa gactttctgt gtcggcatca aatttaactc tacagaccat caatctgaaa
    39181 cggagatgaa agattgtctt gaacagctac atttaatctc agatgccggt gtggactttt
    39241 tggagatcag tggcggtaca ttcgaaaatc ctacattcaa cctaggtgtc tctgatcaaa
    39301 aggccaaagt cagtacgcaa acacgggagg ctttctttgt tgattttgca aagtctattc
    39361 gttcagagtt aagtgggtta cccctcatgg taacaggggg ttttcgcacg cgccaaggta
    39421 tggagactgc tctggtcgag gacagttgtg atgtagtagg cattgcaagg cctgcagtgt
    39481 tgagcccata ccttccacgg aatatcattt tcaaccggga cgtagtggat gcggaagcta
    39541 tagctcacgc agaaaagatt gatacgccaa caatcgcaaa gtggatggga atcaaagcga
    39601 ttggtgttgg ggccgaaacg gtaagtaaat ttactgcaag tattatggat acatggttca
    39661 ccaaaactaa tgtcaatttt tctacgtgta gatatggtac atcaagaaaa ttcagaacct
    39721 aggctcaatt gaaactgagt tatgattcgg gaaaaccgcg cagataaaaa ctgaaggggg
    39781 ggaatgtaaa ttgatattat tcggcttcta aactagtcta cagtcatagg tgctaaacta
    39841 agtgaaaatt tgaagcactc tcttctacat atataatggt cattgcattg ctctcctctg
    39901 gccgaaatat catttagtat tttcacaaga caagattcgt aaaggcaaat attcgtagac
    39961 tggatgttcc attaacagct ctatgttgaa agagtacacg ctttatgcaa atcgactgat
    40021 cataaaccgt caccacactt gtagaagggc gtggaagatg gagttctaaa ctcatgatat
    40081 gggtataacg taaagatttt tcagcttagc catgattaga tctagcccat ctcgaaggcc
    40141 cttctcttca ctgcagacgt ctactccaat taagtctctt aagagagtgt ctgaatagcc
    40201 tggtcgtgtt tggggctgat tgtcgatggt tcgagcggcc aatcgccgca ctttgtcgca
    40261 tagttcatcc gagtgatggg ttatcagttg aataagcatt gctatgtgta gctgaggact
    40321 aactgccgcc tgcagtgttc ctatccggat cggcaacaaa tccaactcct cgcctggata
    40381 catctcggcc catgctaacg tatcattgag catgactatc atgcacttgt atgatcggat
    40441 gacctgtata taacatacga gtgccagtcg cagcacaatg ctatcaacct tttgaaaata
    40501 tgatccggac gcattttcct gggcgggtct cctacactcg tgaaagccag aagccaacaa
    40561 gttttccttg gacaaattcc caacgtttaa gaacgcgggg cgagaaactt gccatttatc
    40621 ccgcatcgga atgatgttag aggttgcgaa tctttccggg aggagtttat tcaaagcttg
    40681 gatgaatgat tgtgttgttt ggacaacacg atccagagtt gttttccagt cgccactttg
    40741 cggagtctct ggcatttcta tctcgtggag ttgtaaattt atttgcgata gtaacggaat
    40801 tggatcgatc atatgtttct ggcgatggtt gcccttttcc agcgcagggt cagtatttgg
    40861 gattccggcc gaaataggtg gttcttccat atcaaaaccg cttgctgtgt ctgattgcca
    40921 ttcacgaccc agaagttcag accatggtcc gtccattgca tttgttggag tcccatagag
    40981 cgaatctggt gttacgatag atctattcac atccaagttg cagtctccag gtgaccacca
    41041 gaagtcgaca ctttcgtccg acactgttgg cagtgcgctg gaagcggttg cagtcgtgca
    41101 atctgaacgc gacgtgtcgg agtcaccggt tgcgagtgaa aaggcagaca tcatattgtt
    41161 ggtgataaaa gtcggaccag ccgtagtcac agatgatata ccatcccgga tttcagcaac
    41221 gcaagaagta ggcaagttga gagaacgagg ggttcctgtt gcttcgttct ctttcggctt
    41281 atcttccttt ggcttcctag tctttggtct acccgaacgc aggggaggac tgtaaacaca
    41341 tttctcacca gcttctttac agcggcggca tggcttgtcg tcttgagctc cactgcgtgt
    41401 gcatcgttgc tttcgcctgt gacatcggtc gcacgattgt cgaagaggag aggcgctgtc
    41461 gaataggagc atagtcgttt gagcctgtat tgattgattt ccttctttag atgcgtatac
    41521 cagtctgtct tcatcagtac cttggagatc tgctatgacg gattaatgtg tattattcag
    41581 tagatcactg ccatagacca taattatcaa acgcccggat cacccgtgga gacagtgtat
    41641 gccaggggcg cgaatattcc gagatgatca gccttgtcga atcatttgtc acactagcgt
    41701 tgccactgta cttgtacttc ggtaagctaa tagctgcctc tcatttcccc ggcaaacttt
    41761 agtcggtatt ccgtactctt gtttctccgg gagcccgctt gcgggtcatg ggggccgcca
    41821 gggtcatgtc ctatatgtta gttagggatc aa
//
