BGC0002111: andalusicin A biosynthetic gene cluster from Bacillus thuringiensis serovar andalousiensis NRRL B-23139
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Location: 3,149,977 - 3,156,657 nt. (total: 6,681 nt).
This entry is originally from NCBI GenBank CP035727.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002111
Short description andalusicin A biosynthetic gene cluster from Bacillus thuringiensis serovar andalousiensis NRRL B-23139
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
CP035727.2
3149977 - 3156657
via Knock-out studies, Enzymatic assays, Heterologous expression, Gene expression correlated with compound production
Compounds
  • andalusicin A
  • andalusicin B
Species Bacillus thuringiensis serovar andalousiensis NRRL B-23139 [taxonomy]
References
Chemical products information
andalusicin A Evidence: NMR, Mass spectrometry, Total synthesis
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C107H147N27O26S1
Chemical database entries
NPAtlas
andalusicin B Evidence: Mass spectrometry
(no structure information available)
C105H143N27O26S1
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • EVG22_16510
  • QIW19938.1
 3149977 - 3150828 (+) ABC transporter ATP-binding protein
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    • EVG22_16515
    • QIW19939.1
    		 3150829 - 3151479 (+) ABC-2 transporter permease
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      • EVG22_16520
      • QIW19940.1
      • lanKC
      		 3151756 - 3154374 (+) class III lanthionine synthetase LanKC
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        • EVG22_32215
        • QQY95970.1
        		 3154410 - 3154547 (+) class III lanthipeptide
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          • EVG22_32220
          • QQY95971.1
          		 3154584 - 3154721 (+) class III lanthipeptide
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            • EVG22_32225
            • QQY95972.1
            		 3154758 - 3154895 (+) class III lanthipeptide
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              • EVG22_32230
              • QQY95973.1
              		 3154932 - 3155069 (+) class III lanthipeptide
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                • EVG22_32235
                • QQY95974.1
                		 3155106 - 3155243 (+) class III lanthipeptide
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                  • EVG22_32240
                  • QQY95975.1
                  		 3155280 - 3155417 (+) class III lanthipeptide
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                    • EVG22_32245
                    • QQY95976.1
                    		 3155454 - 3155591 (+) class III lanthipeptide
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                      • EVG22_16525
                      • QIW19941.1
                      		 3155824 - 3156657 (+) methyltransferase domain-containing protein
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                        Biosynthesis information
                        Annotation changelog

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-10-07
                        Update chemical activity to schema version 2.11
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-10-07
                        Added chemical structures for compounds: andalusicin A.
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-10-07
                        Added NPAtlas links to compounds: andalusicin A.
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-09-15
                        Entry added
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Fix precursor annotations
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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