BGC0002115: streptamidine biosynthetic gene cluster from Streptomyces albidoflavus J1074
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 6,498,603 - 6,513,041 nt. (total: 14,439 nt).
This entry is originally from NCBI GenBank CP004370.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002115
Short description streptamidine biosynthetic gene cluster from Streptomyces albidoflavus J1074
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (unmodified)
Loci
CP004370.1
6498603 - 6513041
via Knock-out studies, Heterologous expression, Gene expression correlated with compound production
Compounds
  • streptamidine
Species Streptomyces albidoflavus J1074 [taxonomy]
References
Chemical products information
streptamidine Evidence: NMR, Mass spectrometry, Chemical derivatisation
Copy SMILES
C28H42N10O8
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • XNR_5767
  • AGI92072.1
6498603 - 6499856 (-) Oxidoreductase
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f9221949450>
copy AA seq
copy Nt seq
  • XNR_5768
  • AGI92073.1
6500025 - 6501014 (+) ABC Fe(3+) transporter
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f9221949550>
copy AA seq
copy Nt seq
  • XNR_5769
  • AGI92074.1
6501011 - 6502045 (+) iron ABC transporter
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f9221949bd0>
copy AA seq
copy Nt seq
  • XNR_5770
  • AGI92075.1
6502042 - 6503097 (+) Iron ABC transporter
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f922194a550>
copy AA seq
copy Nt seq
  • XNR_5771
  • AGI92076.1
6503220 - 6504056 (+) Iron(III) dicitrate transport system permease
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f922194a390>
copy AA seq
copy Nt seq
  • XNR_5772
  • AGI92077.1
6504125 - 6504259 (+) RiPP Precursor peptide
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f922194a990>
copy AA seq
copy Nt seq
  • XNR_5773
  • AGI92078.1
6504402 - 6505247 (+) E1-like protein
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f922194afd0>
copy AA seq
copy Nt seq
  • XNR_5774
  • AGI92079.1
6505244 - 6506770 (+) Hydrolase CocE/NonD family protein
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f922194aed0>
copy AA seq
copy Nt seq
  • XNR_5775
  • AGI92080.1
6506767 - 6508134 (+) YcaO-domain protein
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f922194b610>
copy AA seq
copy Nt seq
  • XNR_5776
  • AGI92081.1
6508149 - 6509456 (+) dehydrogenase
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f922194bdd0>
copy AA seq
copy Nt seq
  • XNR_5777
  • AGI92082.1
6509515 - 6511260 (+) HlyB/MsbA family ABC transporter
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f922194bcd0>
copy AA seq
copy Nt seq
  • XNR_5778
  • AGI92083.1
6511257 - 6513041 (+) ABC efflux pump
  • Mutation phenotype: <mibig.converters.shared.mibig.gene.function.MutationPhenotype object at 0x7f9221950290>
copy AA seq
copy Nt seq
Biosynthesis information
Annotation changelog

Entry version: 2

Date
Changes
Submitters
Reviewers
Changed chemical structures for compounds: streptamidine.
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
Added NPAtlas links to compounds: streptamidine.
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 1

Date
Changes
Submitters
Reviewers
Submitted
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
Similar known gene clusters from MIBiG 4.0
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.