BGC0002122: gramicidin S biosynthetic gene cluster from Aneurinibacillus migulanus
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Location: 3,284,920 - 3,341,639 nt. (total: 56,720 nt).
This entry is originally from NCBI GenBank LGUG01000004.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002122
Short description gramicidin S biosynthetic gene cluster from Aneurinibacillus migulanus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
LGUG01000004.1
3284920 - 3341639
via Knock-out studies
Compounds
  • gramicidin S
Species Aneurinibacillus migulanus [taxonomy]
References
Chemical products information
gramicidin S Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AF333_17590
  • KON98594.1
 3287411 - 3288931 (+) histidine kinase
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    • AF333_17595
    • KON97020.1
    		 3289179 - 3289451 (+) hypothetical protein
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      • AF333_17600
      • KON97021.1
      		 3289642 - 3290379 (-) cyclase
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        • AF333_17605
        • KON97022.1
        		 3290892 - 3291581 (+) aspartate racemase
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          • AF333_17610
          • KON98595.1
          		 3291784 - 3293406 (-) elongation factor 3
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            • AF333_17615
            • KON98596.1
            		 3293821 - 3295872 (-) aminopeptidase
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              • AF333_17620
              • KON97023.1
              		 3296276 - 3299452 (-) NADPH--cytochrome P450 reductase
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                • AF333_17625
                • KON97024.1
                		 3299799 - 3301070 (-) hypothetical protein
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                  • AF333_17630
                  • KON97025.1
                  		 3301205 - 3302524 (-) hypothetical protein
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                    • AF333_17635
                    • KON97026.1
                    		 3302892 - 3303617 (+) PhoP family transcriptional regulator
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                      • AF333_17640
                      • KON97027.1
                      		 3303601 - 3304680 (+) hypothetical protein
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                        • AF333_17645
                        • KON97028.1
                        		 3304920 - 3318272 (-) phenylalanine racemase
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                          • AF333_17650
                          • KON97029.1
                          		 3318343 - 3321639 (-) phenylalanine racemase
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                            • AF333_17655
                            • KON97030.1
                            		 3321666 - 3322436 (-) gramicidin dehydrogenase
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                              • AF333_17665
                              • KON98597.1
                              		 3323801 - 3324127 (-) hypothetical protein
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                                • AF333_17670
                                • KON97031.1
                                		 3324215 - 3324946 (-) multidrug ABC transporter permease
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                                  • AF333_17675
                                  • KON97032.1
                                  		 3324961 - 3325713 (-) ABC transporter permease
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                                    • AF333_17680
                                    • KON97033.1
                                    		 3325710 - 3326621 (-) bacitracin ABC transporter ATP-binding protein
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                                      • AF333_17685
                                      • KON97034.1
                                      		 3326785 - 3327492 (+) DNA-binding protein
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                                        • AF333_17690
                                        • KON97035.1
                                        		 3327497 - 3328900 (+) histidine kinase
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                                          • AF333_17695
                                          • KON97036.1
                                          		 3329046 - 3329645 (-) TetR family transcriptional regulator
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                                            • AF333_17700
                                            • KON97037.1
                                            		 3329763 - 3330302 (+) membrane protein
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                                              • AF333_17705
                                              • KON97038.1
                                              		 3330526 - 3331062 (-) streptothricin acetyltransferase
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                                                • AF333_17710
                                                • KON97039.1
                                                		 3331088 - 3331864 (-) hypothetical protein
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                                                  • AF333_17720
                                                  • KON97040.1
                                                  		 3332904 - 3333440 (-) hypothetical protein
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                                                    • AF333_17725
                                                    • KON97041.1
                                                    		 3333610 - 3334056 (-) hypothetical protein
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                                                      • AF333_17730
                                                      • KON98598.1
                                                      		 3334077 - 3334682 (-) hypothetical protein
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                                                        • AF333_17735
                                                        • KON98599.1
                                                        		 3335709 - 3336404 (+) hypothetical protein
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                                                          • AF333_17740
                                                          • KON97042.1
                                                          		 3336491 - 3337435 (-) serine protease
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                                                            • AF333_17745
                                                            • KON97043.1
                                                            		 3337456 - 3337725 (-) hypothetical protein
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                                                              • AF333_17750
                                                              • KON97044.1
                                                              		 3337855 - 3338502 (-) hypothetical protein
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                                                                • AF333_17755
                                                                • KON97045.1
                                                                		 3338635 - 3339858 (-) hypothetical protein
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                                                                  Biosynthesis information
                                                                  Annotation changelog

                                                                  Entry version: next

                                                                  Date
                                                                  Changes
                                                                  Submitters
                                                                  Reviewers
                                                                  2024-08-18
                                                                  MIBiG v4 annotathon
                                                                  • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                  Entry version: 1

                                                                  Date
                                                                  Changes
                                                                  Submitters
                                                                  Reviewers
                                                                  2022-09-15
                                                                  Entry added
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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