BGC0002137: mutaxanthene A biosynthetic gene cluster from Streptomyces sp. NRRL F-3213
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Location: 183,729 - 216,609 nt. (total: 32,881 nt).
This entry is originally from NCBI GenBank NZ_JOIQ01000020.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002137
Short description mutaxanthene A biosynthetic gene cluster from Streptomyces sp. NRRL F-3213
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
NZ_JOIQ01000020.1
183729 - 216609
via Gene expression correlated with compound production
Compounds
  • mutaxanthene A
  • mutaxanthene B
  • mutaxanthene D
Species Streptomyces sp. NRRL F-3213 [taxonomy]
References
Chemical products information
mutaxanthene A Evidence: NMR [1]
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C22H18O10
Chemical database entries
NPAtlas
PubCHEM
mutaxanthene B Evidence: NMR [1]
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C23H20O10
Chemical database entries
PubCHEM
NPAtlas
mutaxanthene D Evidence: NMR [1]
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C22H21N1O9
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • IF70_RS33675
  • WP_037817171.1
 183760 - 184101 (-) PadR family transcriptional regulator
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    • IF70_RS33680
    • WP_037817174.1
    		 184177 - 184767 (-) hypothetical protein
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      • IF70_RS33685
      • WP_037817176.1
      		 184930 - 185202 (-) hypothetical protein
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        • IF70_RS33690
        • WP_037817178.1
        		 185531 - 186526 (-) acyltransferase domain-containing protein
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          • IF70_RS33695
          • WP_037817180.1
          		 186678 - 187712 (+) ketoacyl-ACP synthase III family protein
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            • IF70_RS33700
            • WP_037817183.1
            		 187770 - 188543 (-) cyclase family protein
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              • IF70_RS33705
              • WP_037817185.1
              		 188560 - 189309 (-) SDR family oxidoreductase
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                • IF70_RS33710
                • WP_051729283.1
                		 189306 - 191159 (-) AMP-binding protein
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                  • IF70_RS33715
                  • WP_037817187.1
                  		 191152 - 192111 (-) aromatase/cyclase
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                    • IF70_RS33720
                    • WP_037817190.1
                    • fabG
                    		 192125 - 192910 (-) 3-oxoacyl-ACP reductase FabG
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                      • IF70_RS33725
                      • WP_037817193.1
                      		 192907 - 194142 (-) FAD-dependent monooxygenase
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                        • IF70_RS33730
                        • WP_037817196.1
                        		 194302 - 194763 (+) nuclear transport factor 2 family protein
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                          • IF70_RS33735
                          • WP_051729288.1
                          		 194766 - 195182 (+) nuclear transport factor 2 family protein
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                            • IF70_RS33740
                            • WP_037817202.1
                            		 195599 - 196357 (-) SDR family oxidoreductase
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                              • IF70_RS33745
                              • WP_051729290.1
                              		 196525 - 197547 (+) methyltransferase
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                                • IF70_RS33750
                                • WP_051729292.1
                                		 197569 - 199098 (-) MFS transporter
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                                  • IF70_RS33755
                                  • WP_037817205.1
                                  		 199134 - 199391 (-) acyl carrier protein
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                                    • IF70_RS33760
                                    • WP_037817208.1
                                    		 199492 - 200697 (-) ketosynthase chain-length factor
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                                      • IF70_RS33765
                                      • WP_051729294.1
                                      		 200694 - 201986 (-) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
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                                        • IF70_RS33770
                                        • WP_078870628.1
                                        		 202151 - 204238 (-) AfsR/SARP family transcriptional regulator
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                                          • IF70_RS33775
                                          • WP_037817213.1
                                          		 204361 - 205116 (-) SDR family oxidoreductase
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                                            • IF70_RS33780
                                            • WP_078870630.1
                                            		 205151 - 206761 (-) FAD-dependent oxidoreductase
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                                              • IF70_RS33785
                                              • WP_037817215.1
                                              		 206698 - 207720 (-) methyltransferase
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                                                • IF70_RS33790
                                                • WP_051729299.1
                                                		 207987 - 209501 (+) FAD-dependent monooxygenase
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                                                  • IF70_RS33795
                                                  • WP_078870629.1
                                                  		 209731 - 213414 (+) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
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                                                    • IF70_RS33800
                                                    • WP_037817217.1
                                                    		 213512 - 213961 (-) nitroreductase family deazaflavin-dependent oxidoreductase
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                                                      • IF70_RS33805
                                                      • WP_078870631.1
                                                      		 214082 - 215350 (+) FAD-dependent oxidoreductase
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                                                        • IF70_RS33810
                                                        • WP_037817219.1
                                                        		 215410 - 216609 (+) MFS transporter
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                                                          Biosynthesis information
                                                          Annotation changelog

                                                          Entry version: next

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2024-03-19
                                                          MIBiG v4 annotathon
                                                          • (ID: K5UBFDWZSYOHS4HI42NVQMJK)
                                                          • (ID: YO3TP6VWB5CBNPZKNYNQSKUW)
                                                          • (ID: NNE55MAGQGEH7CW7BAZQXJ3P)
                                                          • (ID: CVBS4CX3MGQ2Y6Q45INSO263)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 2

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-10-07
                                                          Added NPAtlas links to compounds: mutaxanthene B, mutaxanthene C, mutaxanthene A.
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 1

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-09-15
                                                          Submitted
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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