BGC0002138 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002138 (Streptomyces albireticuli)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	9,694	fuelimycin A/fuelimicin B/fuelimicin C	PKS:Iterative type I	100%

BGC0002138 - Region 1 - T1PKS

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Location: 1 - 9,694 nt. (total: 9,694 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 9,695
Label		BGC0002138

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002138	1.00	Polyketide	fuelimycin A, fuelimicin B, fuelimicin C	Streptomyces albireticuli NRRL B-1670
BGC0001002	0.31	NRP, Polyketide	jawsamycin	Streptomyces roseoverticillatus
BGC0000867	0.26	Other	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0000866	0.26	Other	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000056	0.25	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000231	0.22	Polyketide	griseusin A, griseusin B	Streptomyces griseus
BGC0001276	0.22	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001998	0.21	Polyketide	aspernidgulene A1, aspernidgulene A2, aspernidgulene B1	Aspergillus nidulans FGSC A4
BGC0001275	0.21	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001244	0.21	Polyketide	(-)-Mellein	Parastagonospora nodorum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002138	1.00	Polyketide	fuelimycin A, fuelimicin B, fuelimicin C	Streptomyces albireticuli NRRL B-1670
BGC0001002	0.64	NRP, Polyketide	jawsamycin	Streptomyces roseoverticillatus
BGC0000867	0.60	Other	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0000866	0.59	Other	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000056	0.58	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000231	0.55	Polyketide	griseusin A, griseusin B	Streptomyces griseus
BGC0001276	0.54	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001998	0.54	Polyketide	aspernidgulene A1, aspernidgulene A2, aspernidgulene B1	Aspergillus nidulans FGSC A4
BGC0001275	0.54	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001244	0.54	Polyketide	(-)-Mellein	Parastagonospora nodorum

Similar known gene clusters from MIBiG 4.0

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 9694:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

CK936_29005

PKS_AT (561..855): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 70.8%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 155.3
inactive: 89.5
Methoxymalonyl-CoA: 86.5
Methylmalonyl-CoA: 76.9
Propionyl-CoA: 46.4
Isobutyryl-CoA: 37.2
fatty_acid: 36.1
Ethylmalonyl-CoA: 35.2
Acetyl-CoA: 33.2
2-Methylbutyryl-CoA: 28.4
CHC-CoA: 27.8
Benzoyl-CoA: 15.3
trans-1,2-CPDA: 12.9
3-Methylbutyryl-CoA: 6.6