BGC0002143: griseusin biosynthetic gene cluster from Streptomyces sp. CA-256286
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Location: 828,898 - 868,146 nt. (total: 39,249 nt).
This entry is originally from NCBI GenBank CP071044.1.

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core biosynthetic genes
additional biosynthetic genes
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resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002143
Short description griseusin biosynthetic gene cluster from Streptomyces sp. CA-256286
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
CP071044.1
828898 - 868146
via Gene expression correlated with compound production
Compounds
  • griseusin
Species Streptomyces sp. CA-256286 [taxonomy]
References
Chemical products information
griseusin Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • JHY03_06920
  • QTA30576.1
828899 - 830251 (+) adenosylmethionine--8-amino-7-oxononanoate transaminase
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    • JHY03_06930
    • QTA30577.1
    830253 - 830948 (+) ATP-dependent dethiobiotin synthetase BioD
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      • JHY03_06940
      • QTA30578.1
      831052 - 831738 (+) class I SAM-dependent methyltransferase
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        • JHY03_06950
        • QTA30579.1
        831751 - 832122 (-) hypothetical protein
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          • JHY03_06960
          • QTA30580.1
          832119 - 832346 (-) toxin-antitoxin system HicB family antitoxin
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            • JHY03_06970
            • QTA30581.1
            832461 - 832886 (+) GNAT family N-acetyltransferase
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              • JHY03_06980
              • QTA30582.1
              833055 - 834392 (+) HlyC/CorC family transporter
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                • JHY03_06990
                • QTA30583.1
                834389 - 835408 (+) HlyC/CorC family transporter
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                  • JHY03_07000
                  • QTA30584.1
                  835477 - 836382 (+) SGNH/GDSL hydrolase family protein
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                    • JHY03_07010
                    • QTA30585.1
                    • rfbB
                    836432 - 837430 (-) dTDP-glucose 4,6-dehydratase
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                      • JHY03_07020
                      • QTA30586.1
                      837490 - 838320 (-) transcriptional regulator
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                        • JHY03_07030
                        • QTA30587.1
                        838360 - 839535 (-) DegT/DnrJ/EryC1/StrS family aminotransferase
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                          • JHY03_07040
                          • QTA30588.1
                          839770 - 840555 (+) SDR family NAD(P)-dependent oxidoreductase
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                            • JHY03_07050
                            • QTA30589.1
                            840614 - 841561 (+) actinorhodin polyketide synthase bifunctional cyclase/dehydratase
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                              • JHY03_07060
                              • QTA30590.1
                              841558 - 842403 (+) short chain dehydrogenase
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                                • JHY03_07070
                                • QTA30591.1
                                842503 - 843669 (-) acyltransferase
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                                  • JHY03_07080
                                  • QTA30592.1
                                  • hcaB_1
                                  843804 - 844619 (-) 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase
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                                    • JHY03_07090
                                    • QTA30593.1
                                    844738 - 845805 (-) luciferase family protein
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                                      • JHY03_07100
                                      • QTA30594.1
                                      845808 - 846266 (-) nuclear transport factor 2 family protein
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                                        • JHY03_07110
                                        • QTA30595.1
                                        846348 - 847493 (-) hydrolase
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                                          • JHY03_07120
                                          • QTA30596.1
                                          847841 - 848626 (-) regulatory protein
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                                            • JHY03_07130
                                            • QTA30597.1
                                            849296 - 850204 (+) cyclase
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                                              • JHY03_07140
                                              • QTA30598.1
                                              • rfbH
                                              850222 - 851541 (-) lipopolysaccharide biosynthesis protein RfbH
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                                                • JHY03_07150
                                                • QTA30599.1
                                                851538 - 852593 (-) Gfo/Idh/MocA family oxidoreductase
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                                                  • JHY03_07160
                                                  • QTA30600.1
                                                  852590 - 853942 (-) NDP-hexose 2,3-dehydratase
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                                                    • JHY03_07170
                                                    • QTA30601.1
                                                    854122 - 854796 (-) hypothetical protein
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                                                      • JHY03_07180
                                                      • QTA30602.1
                                                      854816 - 855406 (-) NADPH-dependent oxidoreductase
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                                                        • JHY03_07190
                                                        • QTA30603.1
                                                        855639 - 856418 (+) thioesterase
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                                                          • JHY03_07200
                                                          • QTA30604.1
                                                          856415 - 857680 (+) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
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                                                            • JHY03_07210
                                                            • QTA30605.1
                                                            857677 - 858933 (+) ketosynthase chain-length factor
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                                                              • JHY03_07220
                                                              • QTA30606.1
                                                              858960 - 859232 (+) acyl carrier protein
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                                                                • JHY03_07230
                                                                • QTA30607.1
                                                                859330 - 860307 (+) actinorhodin polyketide synthase bifunctional cyclase/dehydratase
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                                                                  • JHY03_07240
                                                                  • QTA30608.1
                                                                  • rfbA
                                                                  860377 - 861378 (-) glucose-1-phosphate thymidylyltransferase
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                                                                    • JHY03_07250
                                                                    • QTA30609.1
                                                                    • desVI
                                                                    861580 - 862290 (+) dTDP-3-amino-3,4, 6-trideoxy-alpha-D-glucopyranose
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                                                                      • JHY03_07260
                                                                      • QTA30610.1
                                                                      862398 - 863456 (+) hypothetical protein
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                                                                        • JHY03_07270
                                                                        • QTA30611.1
                                                                        863621 - 864778 (+) glycosyl transferase family protein
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                                                                          • JHY03_07280
                                                                          • QTA30612.1
                                                                          864922 - 865656 (+) sorbitol utilization protein SOU2
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                                                                            • JHY03_07290
                                                                            • QTA30613.1
                                                                            865775 - 867169 (-) export protein
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                                                                              • JHY03_07300
                                                                              • QTA30614.1
                                                                              • qor
                                                                              867166 - 868146 (-) NADPH:quinone reductase-dependent oxidoreductase
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                                                                                Biosynthesis information
                                                                                Annotation changelog

                                                                                Entry version: 1

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                                                                                Entry added
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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