LOCUS       BGC0002146             30117 bp    DNA     linear   PLN 18-JAN-2021
DEFINITION  Cladobotryum sp. isolate 11231 FR901483 gene cluster, complete
            sequence.
ACCESSION   BGC0002146
VERSION     BGC0002146
KEYWORDS    .
SOURCE      Cladobotryum sp
  ORGANISM  Cladobotryum sp.
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae;
            Cladobotryum.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:01:53
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 30117
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     mRNA            complement(join(<1..516,660..1190,1241..>1477))
                     /product="FrzF"
     CDS             complement(join(1..516,660..1190,1241..1477))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 236.9; E-value:
                     5.9e-72)"
                     /gene_kind="biosynthetic-additional"
                     /note="O-methyltransferase"
                     /product="FrzF"
                     /protein_id="QQO98476.1"
                     /transl_table=11
                     /translation="MSTIRGTLSELSRAADAFAHEVDEAGYGDYTFLPDNSPFDLSFLT
                     SKGLEARGSLIAAAEKILRLAKGPQGCLASFADTKGIEMGTIQALTQLEVPDKVPLQGS
                     ITYEELAGVIRVAPELLQRLVRLAALAGFLIEDESGAVRHTAMSAVFLRDTAAGDTARF
                     LFDVDMRAYSFFADSLRLDPSGQNIGDGPTALAFQHDSDDQGNRPTIWDILERNPIQRA
                     RFHSTMQALGSFPSHLLKHILVAHDWHSIGSLVDVGGSLGHASLVIAENFPEIRITVQD
                     LPDVVERGRSSLPTVPHAERVSFQAHDLFQEQAIIADAYFLRQILHDWPDGDAERIVRC
                     LIPAMRPGAKLLIMDIVVPEPGAISPYMEKYLRTYDVSMFSMFSAKERTVQQLRDLVER
                     CSARLQFQGISCPPGSATSLLSWVYSAE"
     source          1..30117
                     /country="Japan: Iwaki City 11231 Fukushima prefecture"
                     /db_xref="taxon:2040732"
                     /isolate="11231"
                     /mol_type="genomic DNA"
                     /organism="Cladobotryum sp."
     misc_feature    1..30117
                     /note="FR901483 gene cluster"
     subregion       1..30117
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="NRPS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..30117
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            <2620..>3489
                     /product="FrzE"
     CDS             2620..3489
                     /codon_start=1
                     /note="N-methyltransferase"
                     /product="FrzE"
                     /protein_id="QQO98477.1"
                     /transl_table=11
                     /translation="MAVVERDSDYYDSSYLADYYESLWTDHAALEDIAVYWAFFKERVL
                     LSQSRVDSKFFLLDVGTGTGRVLHSLIDKAVNDADMSLDAMQFVGMDKSPFMLEQAQRA
                     KQLPQEVRASWFVGTATALEDIASLADPHGKANLLIFAFSGINHLHQPGEIDQFFLSAR
                     RVLLPGGLALVSVCAPLLDIEGGDSVPNPYGQVKEVKSKRLEGILYREWETGQKIEGHL
                     FTNSLKTDVVQVSQDGSERVIERNIHNIPLTLLTRDGLRRSAAAAKLEIIEERCIRDEV
                     IFALRAVG"
     mRNA            complement(<3644..>4021)
                     /product="FrzH"
     CDS             complement(3644..4021)
                     /codon_start=1
                     /note="aldolase"
                     /product="FrzH"
                     /protein_id="QQO98478.1"
                     /transl_table=11
                     /translation="MAKHITSSEYDAVIATAYCYVEAMEKGSSKRAKEGFHPDGGIYGY
                     VDGEFKGGSISNLFDFLDQSPEGHKIKAHLDVIAMTPTTAIVKTEVEMNPPETDYTDFL
                     GMVKIDGKWQIVSKIFHSYPR"
     mRNA            <5323..>6243
                     /product="FrzG"
     CDS             5323..6243
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /note="a-KG dependent oxygenase"
                     /product="FrzG"
                     /protein_id="QQO98479.1"
                     /sec_met_domain="PhyH (E-value: 8.9e-33, bitscore: 104.0,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERIPASAGPEAIFEAFRRDGIIVIEGFLTPDQVQRFSSEVQPGL
                     DELTVGAPEHDEAAQTATVMDEMIGEKTKRLGQLVTRSAVFRHELLEHELMHALLEKVF
                     VEGPMDGYWMNASEVIEIAPGSNAQPIHRDQELYDVWNRAGPAMPEAICNFISALTPFT
                     ALNGATQVAPGTHRDFTSDHLLDRDFQGRSDLKTIPAVMNPGDCIFFSGKILHGGGANH
                     TADELRRGLAMSFIRRILTPEEAHPLSVSREIVDTMTYRGQAMLGFRSQWPVIEGVPNF
                     YWTHQGSEIGSHIGLKEKTSGSVVL"
     mRNA            complement(join(<6486..6894,6946..7376,7435..>7752))
                     /product="FrzJ"
     CDS             complement(join(6486..6894,6946..7376,7435..7752))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /note="phosphotransferase"
                     /product="FrzJ"
                     /protein_id="QQO98480.1"
                     /sec_met_domain="APH (E-value: 3.5e-09, bitscore: 26.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTTERESDPIAALILDRLSCTEYACSSLSRVNGGLMNFIYRGTL
                     SRPLPDGATTVIVKHAEEYLSGIEGLSLSTYRSVIAAITLSFGYCVMDVESVQTNRYCV
                     ALDEVEVAVPRVYKFDAESNTQILEDITGYITVCEFLTSRCTQSTSPAFTTRLGFRLGS
                     WLGGLHAWGEGRSPAEIIGGVEENQEAQDGSFDFFYGNPVRRVEQFPHLLGDCKEVLEQ
                     IRDRAAREQKSRTGEKFGFVHGDILSRKSVLIPGDSVTRDQHLRFVIIDWELSQYECHF
                     RECGEVLGDLYLLKRFQDIDGAMSIIQGFLEGYPPLNEDAIFRTAIYLGLFLLANEVTL
                     STDYPKQQIEDFVILARDLVLAGWHKDRETLAKTVFGPVFFRAMN"
     mRNA            <9404..>10942
                     /product="FrzL"
     CDS             9404..10942
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 186.1; E-value: 1.9e-56)"
                     /gene_kind="biosynthetic-additional"
                     /note="P450"
                     /product="FrzL"
                     /protein_id="QQO98481.1"
                     /sec_met_domain="p450 (E-value: 1.4e-69, bitscore: 224.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYRETMLAFVPYLAVFVACYGLVYYRRKRQRLPLPPGPPQLPLV
                     GNLYQIPEMNPWRTYREWHQKYGPIITVKSGLTNTIILGSHKAARDLLDKRNRNYGSRP
                     HFILIGDFIYGGNQTSLLPTGQRWRIHRRILSAFGNVRTSQRYRILYDAESKRLLREIL
                     HGGDFFEPFHHYFVRILFALTYGKRVTGSHDPEARDVIEIVDVVLKEASRSSVPEAFPI
                     LNSLPGALAPWKRRAQLLFEQHSRLFDNHMNAALANKPWNFCKQALRLKASSEVDRVEL
                     NFILGSITEATHSGSMVLGVFIMANILHPDAVRWVQEEIDRVIGPDRLPSFDDMAKLPY
                     LNAYLLEVMRWRPITPGGMPHASFQDDEYMGYHIPKGTTVVANHWSMDFDESVFTDPYE
                     FRPQRWIEDPNLPSIAFGFGTRICPGRHIAESSIFIVAARLLWSFNFDYAYEDGKRQEI
                     DSWNMTQGLDSGPMPFKASFKIRSPKHQEVMDRECGVSDLDIDAILDKIGADFL"
     mRNA            complement(join(<11973..12138,12233..12399,12451..13566,
                     13643..>13681))
                     /product="FrzC"
     CDS             complement(join(11973..12138,12233..12399,12451..13566,
                     13643..13681))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 306.1; E-value: 7.6e-93)"
                     /gene_kind="biosynthetic-additional"
                     /note="P450 for C-N bond coupling"
                     /product="FrzC"
                     /protein_id="QQO98482.1"
                     /sec_met_domain="p450 (E-value: 3.7e-56, bitscore: 180.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLLQRAGLVVGLWVTYHILLGTYNVFFHPLRRFPGPRLAAATQL
                     VNVYYIIRGINCKYLYELHEKYGDVVRTGPNELSFRTASAIRTIYGGNPGPDDTFHKNM
                     IANIQETGDSDNLFFATGQQHNRYRRLIMPVFAERTIQGQGPMMQEYCSQLIQGLRNRC
                     GRGYFPTQDGVVDIVPWTHFIISDILSHMLFGSGMNCLLNGDYHPWVMAGYKALIESTY
                     IEAAHRLRPYHRILEYLLIPTRLRDGFRVHSAVSREKLQARSKEAEPYQFSLPSFTSES
                     LSEQELFDNINVIATAAGETTSSALSAIMYYLTANPAAYDKAVTEVRQAFSNEAEITAA
                     SSASLPYLKAVIREAFRIRPTIPVGLHRLTPKGGREIDGKWVPAGTWISVANLAACRTS
                     SHWKEAGRFIPERWLGDPEFASDNRDTSVPYSIGVRNCIGMSHANTQLRLILSRLLWNF
                     DFEACPGNADPYDYLEYGTWQVEPLKLRVVDIRGQPK"
     mRNA            <14072..>15199
                     /product="FrzD"
     CDS             14072..15199
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     310.5; E-value: 2.3e-94)"
                     /gene_kind="biosynthetic-additional"
                     /note="old yellow enzyme"
                     /product="FrzD"
                     /protein_id="QQO98483.1"
                     /transl_table=11
                     /translation="MDNSSRLFSPLRLGKCQLRHRVAMSPLTRFRADDLSVQMPFAKEY
                     YAQRASVPGTFLVSEATSISRESVGFSNVPGIWNAEQVRAWKEIADDVHCKGSFLFLQL
                     WATGRSATPERLQSGDFDFASSSAVPMEPGGAVPRELTEEDIHDLIARFAEAARRAIDA
                     GMDGIELHAANGYLIDQFTQASCNQRTDRWGGSIENRARFAIEVTRSVVAAVGADRVGV
                     KLSPWGKIQGMGTMQDLVPQFQYLVSELRDMGLAYLRLSNSRWIDGVPQEEEDNSIYVH
                     TWGASRPVLLEGGYDPISAQKEADIRFNGYDAVIAFGRFFISNPDLPFRIKAGVDLQKY
                     NRDTFYTPISEKGYIDYPFSTAFLEEHSSKASLKL"
     mRNA            <15597..>16373
                     /product="FrzI"
     CDS             15597..16373
                     /NRPS_PKS="Domain: PKS_KR (12-170). E-value: 4.1e-19.
                     Score: 61.0. Matches aSDomain:
                     nrpspksdomains_QQO98484.1_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     213; E-value: 8e-65)"
                     /gene_kind="biosynthetic-additional"
                     /note="SDR keto reduction"
                     /product="FrzI"
                     /protein_id="QQO98484.1"
                     /sec_met_domain="adh_short (E-value: 9.1e-42, bitscore:
                     132.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.4e-34, bitscore:
                     108.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPPPSLLDKAAIVTGGSRGIGAAIAIELARRGAHVLITYNTASH
                     KAQLVAEEIQKLGRKATVVQASSTDREGPNRIVQAAVSQYGRIDIIVNNAGMADDCLLQ
                     DLTHEFWDRIMDVNLRLPAFLVQAALQHLGPAPRIVNISSLAARAGYNATSVYAASKAA
                     LEGMTRAWATELGHRYNVTVNCVNPGPVDTDIMAVDENTDAEVVAYWNAKVKETPAAPR
                     VGTPGDIAQIVAFLCEEGSRWCTGSVVNANGGLVTV"
     CDS_motif       15633..15707
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QQO98484.1_0001"
                     /evalue="3.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="QQO98484.1"
                     /protein_end="37"
                     /protein_start="12"
                     /score="19.9"
                     /tool="antismash"
                     /translation="IVTGGSRGIGAAIAIELARRGAHVL"
     aSDomain        15633..16106
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QQO98484.1_PKS_KR.1"
                     /evalue="4.10E-19"
                     /label="QQO98484.1_PKS_KR.1"
                     /locus_tag="QQO98484.1"
                     /protein_end="170"
                     /protein_start="12"
                     /score="61.0"
                     /tool="antismash"
                     /translation="IVTGGSRGIGAAIAIELARRGAHVLITYNTASHKAQLVAEEIQKL
                     GRKATVVQASSTDREGPNRIVQAAVSQYGRIDIIVNNAGMADDCLLQDLTHEFWDRIMD
                     VNLRLPAFLVQAALQHLGPAPRIVNISSLAARAGYNATSVYAASKAALEGMTRA"
     mRNA            <22396..>25470
                     /product="FrzA"
     CDS             22396..25470
                     /NRPS_PKS="Domain: AMP-binding (27-425). E-value: 2e-77.
                     Score: 252.3. Matches aSDomain:
                     nrpspksdomains_QQO98485.1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (541-610). E-value: 6.6e-15. Score:
                     47.0. Matches aSDomain: nrpspksdomains_QQO98485.1_PCP.1"
                     /NRPS_PKS="Domain: TD (652-898). E-value: 3.3e-67. Score:
                     218.1. Matches aSDomain: nrpspksdomains_QQO98485.1_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 261;
                     E-value: 2.9e-79)"
                     /gene_kind="biosynthetic"
                     /note="NRPS(A-T-R)"
                     /product="FrzA"
                     /protein_id="QQO98485.1"
                     /sec_met_domain="AMP-binding (E-value: 1e-78, bitscore:
                     254.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.8e-14, bitscore:
                     43.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.5e-58, bitscore:
                     187.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSHTFNPQAGYDLAVDRNLGLGEIFYNRAQKSHQAIAVCDGGAV
                     LTYGQLHAKAYRLAQELSQWLRLTEKPVGIVVQHGMADVVAQMAVIYAGGSCAPMDPTL
                     PDNQIQGRLKRLDAVCVLTDQANRHRDLGADVLCIDDFDIADLAPEDTLYPVATNLEHC
                     AYLIHTSGTTAEPKAVQIAARSILHVAFYAPLEPVYDTDVVAHANNSSFDVSLFDIWVP
                     LLRGAQIAVINKAVLLDPPMMAREIDRLGITVMATTTAVLNLAAFIYPKAFAKLRLVTI
                     GGEAANVAAIRIILKNGPPAMLFNAYGPTECCVFCLAHQITPADVEHGSIGVSIGKPVG
                     RTITYIAGDEGGESDQGELWIGGPGVSPGYFRQPEKNLAAFSDLGEAMTSLENPVRFYR
                     TGDIVRRRPNGALEYVGRRDHQVKVRGFRIELEAVEAGLLKTGLFSDAVAMRIEMPQNG
                     AGSILAAYVVPTDVSKPPTMDEALESAKSILPHYMVPQLELVPRLPLNRHLKVDRKQLA
                     ELFGRRWEDVSPAQPENASQDVRSALVSLWATVLASPLSTYGDDDDFLHLGGTSLQAAM
                     LINQIRHKFDIEVSLLTLYDNTTLGALTSIIKQRLSGQSETLHNEKDSWVADSEIADDL
                     SCPLDRPIDWCRDTEGRVFLTGGTGFVGAFLLADLLHMPQTSQVRCLVRATDAAVGQER
                     LRAALDKYGLWEDGFADKLVAIAGLLEDDYLGMGREQFEEAASWASVVFHLGARVNYAQ
                     PYSLHRASNTLGTRNMVRFACAGRTKAIHYVSSIGCFGPTGSILGTTSVREDEPLLPHI
                     TALPYDHGYAQSQWVADALLRRLMDRGFPIAIYRPGFIVGHSQTGACNPDDFLSRLIDA
                     CREIGCYPQLPNQRKEFVPVDYVNAAILHIAASPASLGHAYHIVPPTRAVSIDMDNSMA
                     LVDRAGNSPMRPVSYKEWVERLAATSPKRLLPLQPMLAERVKDGLTRWELYENMPVYET
                     TNTARALQNYPGGLQFPVLDTSLMKRYLDFLEAKG"
     aSDomain        22477..23670
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QQO98485.1_AMP-binding.1"
                     /evalue="2.00E-77"
                     /label="QQO98485.1_AMP-binding.1"
                     /locus_tag="QQO98485.1"
                     /protein_end="425"
                     /protein_start="27"
                     /score="252.3"
                     /tool="antismash"
                     /translation="NRAQKSHQAIAVCDGGAVLTYGQLHAKAYRLAQELSQWLRLTEKP
                     VGIVVQHGMADVVAQMAVIYAGGSCAPMDPTLPDNQIQGRLKRLDAVCVLTDQANRHRD
                     LGADVLCIDDFDIADLAPEDTLYPVATNLEHCAYLIHTSGTTAEPKAVQIAARSILHVA
                     FYAPLEPVYDTDVVAHANNSSFDVSLFDIWVPLLRGAQIAVINKAVLLDPPMMAREIDR
                     LGITVMATTTAVLNLAAFIYPKAFAKLRLVTIGGEAANVAAIRIILKNGPPAMLFNAYG
                     PTECCVFCLAHQITPADVEHGSIGVSIGKPVGRTITYIAGDEGGESDQGELWIGGPGVS
                     PGYFRQPEKNLAAFSDLGEAMTSLENPVRFYRTGDIVRRRPNGALEYVGRRDHQVKVR"
     aSModule        22477..25089
                     /complete
                     /domains="nrpspksdomains_QQO98485.1_AMP-binding.1"
                     /domains="nrpspksdomains_QQO98485.1_PCP.1"
                     /domains="nrpspksdomains_QQO98485.1_TD.1"
                     /final_module
                     /locus_tags="QQO98485.1"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       22600..22632
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QQO98485.1_0001"
                     /evalue="1.40E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="QQO98485.1"
                     /protein_end="79"
                     /protein_start="68"
                     /score="-0.4"
                     /tool="antismash"
                     /translation="TEKPVGIVVQH"
     CDS_motif       22885..22938
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QQO98485.1_0002"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="QQO98485.1"
                     /protein_end="181"
                     /protein_start="163"
                     /score="18.0"
                     /tool="antismash"
                     /translation="AYLIHTSGTTAEPKAVQI"
     CDS_motif       23464..23538
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QQO98485.1_0003"
                     /evalue="1.50E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="QQO98485.1"
                     /protein_end="381"
                     /protein_start="356"
                     /score="30.2"
                     /tool="antismash"
                     /translation="GELWIGGPGVSPGYFRQPEKNLAAF"
     CDS_motif       23635..23700
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QQO98485.1_0004"
                     /evalue="2.60E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="QQO98485.1"
                     /protein_end="435"
                     /protein_start="413"
                     /score="32.4"
                     /tool="antismash"
                     /translation="YVGRRDHQVKVRGFRIELEAVE"
     aSDomain        24019..24225
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QQO98485.1_PCP.1"
                     /evalue="6.60E-15"
                     /label="QQO98485.1_PCP.1"
                     /locus_tag="QQO98485.1"
                     /protein_end="610"
                     /protein_start="541"
                     /score="47.0"
                     /tool="antismash"
                     /translation="ALVSLWATVLASPLSTYGDDDDFLHLGGTSLQAAMLINQIRHKFD
                     IEVSLLTLYDNTTLGALTSIIKQR"
     aSDomain        24352..25089
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QQO98485.1_TD.1"
                     /evalue="3.30E-67"
                     /label="QQO98485.1_TD.1"
                     /locus_tag="QQO98485.1"
                     /protein_end="898"
                     /protein_start="652"
                     /score="218.1"
                     /tool="antismash"
                     /translation="VFLTGGTGFVGAFLLADLLHMPQTSQVRCLVRATDAAVGQERLRA
                     ALDKYGLWEDGFADKLVAIAGLLEDDYLGMGREQFEEAASWASVVFHLGARVNYAQPYS
                     LHRASNTLGTRNMVRFACAGRTKAIHYVSSIGCFGPTGSILGTTSVREDEPLLPHITAL
                     PYDHGYAQSQWVADALLRRLMDRGFPIAIYRPGFIVGHSQTGACNPDDFLSRLIDACRE
                     IGCYPQLPNQRKEFVPVDYVNAAI"
     mRNA            complement(join(<25660..25928,26013..26354,26411..>26810))
                     /product="FrzB"
     CDS             complement(join(25660..25928,26013..26354,26411..26810))
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 77.6; E-value: 1.9e-23)"
                     /gene_kind="other"
                     /note="SDR"
                     /product="FrzB"
                     /protein_id="QQO98486.1"
                     /transl_table=11
                     /translation="MTFIIAVVGATGNQGGSVARSLVQNPSFSVRAITRSPDSQASRSL
                     LSAGAEVVKADGFNGEEMLAAFQGAWGAFVNLNSDDPIWRQPGGPTEFDLGKTIVDAAA
                     GAGVKHLVFSSGPPCVEMTGGKVNMKAMEMKYKIEQYARKLGSFETLTPINPAWYLENF
                     LAEEVAPIFGGFPYFPDEEGYLTFRVPHWAGPGGDNRVPFLGIRDDFGDIIHGIFLNPE
                     RYNGRVIHGVSQLRGFDELVADFEQVTGKKCRYEPVLPSWEAFDIHGIPELEDVKLMFA
                     FTQTTGGRYFAPEPSEADTAAELKRTTAVALGKPEPEQHTLRTKDFFRKHFATEK"
     mRNA            join(<28437..28521,28602..29742,29811..>30117)
                     /product="FrzK"
     CDS             join(28437..28521,28602..29742,29811..30117)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /note="phosphoribosylpyrophosphate amidotransferase"
                     /product="FrzK"
                     /protein_id="QQO98487.1"
                     /sec_met_domain="GATase_7 (E-value: 1.7e-14, bitscore:
                     43.5, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGVLALILANQSSSAANDLHEALYVLQHRGQDAAGIATSTSSGH
                     IHIRKKNGMAADVFQSGARLANLFGSMGIAHLRYPTAGGSANTEAQPFYVNSPYGICFA
                     HNGNLINTVELRRYLDFEIHRHINSDSDSELMLNIFADELSETKKARVNTEDIFNGLSK
                     MYQRCEGAWACTAMLAGFGVIGFRDAYGIRPLVMGSRPSSDGDGLDYMIASESIALDRL
                     GFTNVRDIQPGEAVIVAKGAEPVFCQVAPRKSYTPDLFEYVYFARPDSVIDGISVYQSR
                     QRMGRYLAARLLEVLGPEGIKEIDVVIPVPETSSPAAASVAHALNKPYCAGYIRNPYVF
                     RTFIMPGQATRQKGVRRKLSAVKEEFKNRTILLVDDSIARGTTSREAISMAREAGVKKI
                     IAACCSPEITYPHIYGIDLPSPHEMVAYERDNNDIAQNLGADRIVYQTLEDLQASCAEI
                     ARENDFQEPHTFENGVFSGQYVTPVPEGYFALLEKIRGTGRKEALDKSSKRL"
ORIGIN
        1 ctattccgcc gaataaaccc aggataataa actagtggca ctccctggag gacaggatat
       61 tccttggaac tgcagccgcg cgctacaacg ctctaccaag tcacgtaact gttgcacggt
      121 tcgctccttg gccgagaaca tcgagaacat ggatacgtcg tatgttctca ggtatttttc
      181 catgtaggga gatatcgctc ctggttctgg cacgacaata tccatgatca gaagcttagc
      241 cccaggccgc atggctggga tcaaacaccg cacaatgcgc tctgcgtccc catccggcca
      301 atcatgcaag atctgacgaa gaaagtatgc atctgcaata atggcttgct cctggaacaa
      361 gtcatgcgcc tggaatgaga cgcgctctgc gtgcggaact gtcggtagag aggaacgacc
      421 tcgctcgaca acgtcgggca ggtcttggac tgtgatgcga atttctggga aattctccgc
      481 aatgactagg gaggcgtgcc caagggagcc acctacctgt gtcagccagc agattagaca
      541 aagagcggca cgagagagag agagagagag agagagagag agagagagag agagagagag
      601 aaggggaggg ggagattgag aggaggagga agaggaagag gaagagggtg gtgacgtaca
      661 tcaaccaagg acccgatcga atgccaatcg tgagcaacca aaatatgttt gaggaggtga
      721 gatggaaacg atcccaacgc ctgcatcgta gagtggaacc gcgcacgctg aatcgggttg
      781 cgctccagaa tatcccagat ggtcggccgg ttgccttgat cgtcagagtc atgctggaaa
      841 gcgagcgcgg ttgggccatc cccgatattc tgaccagagg gatccagacg aagtgagtcg
      901 gcgaagaagg agtacgctcg catgtcgaca tcaaacagaa accgagccgt atcgcctgcg
      961 gcggtgtctc gaaggaagac agcggacatg gcagtgtgtc gaacagcacc agactcatcc
     1021 tcgatgagaa agcctgccag agcagctaag cgcaccaatc tttgtagcaa ttctggtgcg
     1081 acccgaatga cgccggcgag ctcctcgtag gtgatggagc cttgcaaagg caccttgtcc
     1141 ggcacttcga gctgggtcag agcctgaatg gtgcccatct cgatcccctt ctacaatgtt
     1201 aaggtcgcag catcaaggga agcggatgga cggatcgtac cgtgtcggca aagctcgcga
     1261 ggcatccctg aggtcccttg gccaggcgaa gaatcttctc agccgcagcg atcaaggagc
     1321 ctcgggcttc gagccctttc gacgttagga atgagaggtc aaagggtgaa ttgtctggga
     1381 gaaaggtgta atctccgtag ccggcttcat ccacttcatg ggcgaaagcg tcggcggcac
     1441 gactgagttc actgagtgtt ccccgtattg ttgacatttt tgcggttgtt ggacgatgct
     1501 tgactttgga gattgcttgg tttcttatat atgacaagat tatgcaccag cctgcaagac
     1561 atgggcaatg agcaagatgg gatcactgaa gatgatgaat acacaatttg aattgtaaat
     1621 catgaaacta tatagactat tattatatta tgatatcttg aaaataaacg ccaactaacc
     1681 aaatatgtta ttgtatatgt tcaaaattta taatttatta tagaatagaa aaataatagt
     1741 aaataaaagt taatagtatt atataataag cttattaaaa cagttagaac ctatacccta
     1801 taaataaggt attaatctat aatgccttaa aattaaggca taaagatttt atatataaat
     1861 aaaagtctta gttttaattc ttaaagtaat aacttaatcc tataataatt taatttttat
     1921 atatagcctt agcctataag atttcgaatt tttaactaaa gcatatgaaa aggttagtga
     1981 attaatatca tatacaaaaa ctaaaaaaac aataatattt attatccata tcttcaagag
     2041 tttattatta ttaaaagatt ttataataac ataataacag tacgttacgt atattttaac
     2101 tataaactta ttattagttt cctttattac acacttttac ccttggaata agactagcct
     2161 ttaatggatt tcttaatatt ttcatttaat tcatgtctta aatgctaaaa gcgcttttta
     2221 ttcaagttat aaaacataac tagttataat agaactaaaa tagcagtata tatattaaat
     2281 taattcttag ttttataaca tagctttgtt ttattactct tattctatat tctatataat
     2341 atatattttc cctttttgcc tatgtaggat tatggtagta tatattacta aggtcgtaag
     2401 taatacagaa acaacaataa taatctttcc gccttgacag acgtgtgcag gcttagtatg
     2461 gttgtatacc atcatgcgcg cttttgtttt ataatggagc tgaatgcggg gtcaaagagc
     2521 tccataatct tctcgctttg aacggtagct aattcatgtc cattctgcta cttatcgtgc
     2581 ttgccgtcga agctccagag gaagacagga gccgcaaaca tggccgtcgt cgagcgcgac
     2641 agtgactatt acgattcatc ctaccttgcc gactactatg agtcgctatg gactgaccat
     2701 gcggcactcg aggacatagc cgtctactgg gctttcttca aggaaagggt cttgttgtcg
     2761 cagagtcgag ttgacagcaa attcttcctt ctcgacgtgg gcacagggac gggccgcgta
     2821 ctacattccc tcatcgacaa ggctgtgaat gacgccgaca tgtctctcga cgccatgcag
     2881 ttcgttggca tggacaaatc ccccttcatg ctcgaacagg cacaacgggc caaacagctt
     2941 ccccaggagg ttcgcgcttc ctggtttgtc ggcactgcca ccgcattgga ggacatagcc
     3001 tcgcttgcag atcctcacgg aaaggcgaat ctgttaatct ttgccttcag cggcatcaat
     3061 cacctccacc agccgggcga gatcgatcaa ttcttcttgt ccgcgcggcg tgtcttgcta
     3121 ccggggggac tggccctggt gtcagtatgt gcgccgctac tggacatcga ggggggggac
     3181 agtgtgccaa atccgtacgg ccaggttaaa gaagtcaaga gcaaacgact cgagggtatt
     3241 ctctatcgcg aatgggaaac gggccagaag attgagggcc atctcttcac caactctctc
     3301 aagactgacg ttgttcaagt cagtcaagac ggcagtgagc gggtgattga gcgcaacatt
     3361 cacaacatcc cattgacgct gctgactcgg gatgggctgc gaaggagcgc tgcggcggcc
     3421 aaactcgaaa tcatagagga gaggtgtata cgagacgaag ttatatttgc gcttagggca
     3481 gtgggctaat ggccccagtc gtgacttata catagttatg aatatatatt acatgatatt
     3541 gacttgccaa aaagacgttg atgacgcgta tgacagaaca tatgtagtct cggtgcagac
     3601 atagcccaaa taccccaaga aaatcttgcc taggtaatcc tgcctatcgc gggtacgagt
     3661 ggaagatctt ggagacaatc tgccacttcc catctatctt gaccatgccc agaaagtcgg
     3721 tgtagtctgt ttcgggtgga ttcatttcaa cttcggtctt gacaattgcg gtcgtcggag
     3781 tcatggcaat cacgtccaga tgagccttga ttttgtgacc ctccggggac tgatccagga
     3841 aatcgaacag gttggagatg gatcccccct tgaactcccc gtcaacgtag ccgtagatgc
     3901 ctccgtccgg gtgaaatcct tccttggccc tcttggagct gcccttctcc atggcttcga
     3961 cgtagcagta ggctgtggcg atgacggcat catattccga actggtgatg tgctttgcca
     4021 tgatggtctt tgtatgatgt atggttgtct atgggcaacg caaggcaaat ctaatcagcg
     4081 acaacaaatt gacttgtgaa acacagttgc ttaggtttga ggtcctcaaa aagagcaaag
     4141 acagaacaca atttgagctg aaaagaggcc tcttttccct ctttccctcc ccttcgtggc
     4201 tagagatggg aaagggccct gttcgctctc tgtaaatgac gatccggccg tactacccac
     4261 actcagccca cagatttgtc tgtatccccc cccccccaat ctctcctatt cactcatatc
     4321 tctgtacata catcgtacat ggagctaact caaccgttcc cttatccggt acccatcaca
     4381 cccctcacac cccacacccc tccctaatct tccgacatgt ctcatttcgg gttatcccgg
     4441 ccaatttcat ctcaagttgc ggggtagatg ggcctgagca agagctatgg ccctcaggga
     4501 gagggggggg gctgcatttc cttgacccgg cgaatgcata tgaatgtatc tattacgttc
     4561 tagactgtgg tagtgcaagc tgtaggtata tgcaatctgg agcatcccag tgtataacgt
     4621 aagtttgctg aaggcccact ccaggttccc ttcccctccg cttcgatcac ttacgtgata
     4681 atctatcaaa ttgctcctta cgccgatgtt gtggccgtgg cgggttatta caatcaggtt
     4741 gcaaaggtct gcgtccacct gacagtgtac cactttgtat tactaaaact tatacctttt
     4801 aaaattctat ataaaatcca gtcttaaata aaaaatatct tttttaaact taatatatat
     4861 ttaaactatt aaaggatctt attatattat tattatattt ttaaactaat cataaaatat
     4921 aataaaacat taaaagtatt atattttata aaatttatat attacctagt attatagtat
     4981 gattaatact gcataattta cttttttaat aatcatatat ttaaatatat ataaattaat
     5041 taatatataa aaaattataa tactctattt aaaaactact tttactatta aaaatctaaa
     5101 ttttataaat tctatgtata tatatatatt aatttataat aagtttttaa agagtataaa
     5161 tcttagtaat ataaggtggc acactgtaag gcggacgcag acctttgtca attaattgta
     5221 tttggctggt gcttatgcat gatagacatc ccgactggat ttggattgtt gcctctcttc
     5281 tccccggagc aaaatacttg ctgtagtcga cgtattctgg ccatggaacg cattcctgct
     5341 tcggccggtc cagaagctat tttcgaagct tttcggagag atggaatcat cgttatcgag
     5401 ggcttcctca ctccagatca ggtgcagcga ttcagcagcg aagttcagcc tgggctggat
     5461 gagctgactg ttggggcacc cgagcatgat gaagctgctc aaacggccac cgtcatggac
     5521 gaaatgatag gggagaagac caaacgactg ggacagttgg tcacgcggag tgccgtgttt
     5581 cgtcacgagc tcctcgagca tgaactgatg catgcgctgt tggaaaaggt tttcgtagag
     5641 ggcccgatgg atggatactg gatgaatgcc agcgaggtca tcgagatcgc cccgggaagc
     5701 aacgcgcagc ccatccatcg ggaccaagag ctctacgatg tctggaatcg cgccggacct
     5761 gccatgcccg aggcgatatg caacttcatc tccgccctca cgccattcac ggccctgaac
     5821 ggggccactc aggtcgcgcc gggcacccac cgggatttca cgagcgacca tctcctggac
     5881 cgagatttcc aggggcgttc cgacctgaag accattccgg ccgtcatgaa ccccggcgac
     5941 tgcatcttct tctccggaaa gatcttgcac ggcggcggtg ccaaccacac ggcggatgag
     6001 ttgcgccgcg gcctcgccat gagtttcatc aggagaattc tgacgccgga ggaagctcat
     6061 ccgctctccg tctcgcgcga gattgtggac acgatgacgt atcggggcca ggcgatgctg
     6121 ggcttccgga gccagtggcc cgtgatcgag ggggtaccca atttctattg gactcaccag
     6181 ggttctgaaa ttggtagcca cattggatta aaggagaaga cgagtggtag tgttgtattg
     6241 tgaatttttg tatacatcta catatctaca tgtcgatgtg cgcgtataag agttggttgt
     6301 ctgcacctag tagtcatgtg ggattagtga ggagcaaggg ttgtagcttc gtatagtaaa
     6361 ttgacctctc tgtgcagtat caaatccaca gccgtgcgtg ttttaaacct gggggttggg
     6421 tcctatgtat agtaagactt gaagcttttt accgctagcc taacgaatag cagggaggaa
     6481 gactgtcaat tcatcgctct gaaaaataca ggcccaaaaa cggtctttgc gagcgtctcc
     6541 cgatccttgt gccaccctgc cagtaccaag tctcttgcaa ggattacaaa gtcttctatc
     6601 tgttgttttg gataatcggt tgacagcgtg acctcatttg ctagtaaaaa gagtcctaga
     6661 taaatggctg tccggaagat ggcgtcctca tttaaggggg gataaccctc tagaaagcct
     6721 tggattatcg acatagcgcc gtcgatgtcc tgaaagcgct tgagcagata gaggtctcca
     6781 agcacctcac cgcattctcg gaaatgacat tcgtactgcg aaagctccca gtcgatgata
     6841 acaaaacgca gatgctgatc gcgtgtaaca gaatcgccag gtataagaac acttctgttc
     6901 ttcagtaaca atccacatgt ggatgagatg ggagtgaagg cttactttct agataagatg
     6961 tccccgtgga caaatccaaa cttctcacca gtcctactct tttgctccct tgcggcgcga
     7021 tctcggatct gttcgaggac ttctttgcaa tctcccaaaa gatgaggaaa ctgttcaacc
     7081 ctccgtacag gattgccata aaagaagtca aaggaaccat cctgtgcttc ctgattctcc
     7141 tctacgccac ctattatttc tgccgggctc cttccttctc cccaggcgtg cagacctcca
     7201 agccagctgc ctagacggaa gcctaggcgg gtagtgaaag caggcgatgt gctctgagtg
     7261 catcgcgacg tcaaaaactc acacactgtg atatatccgg taatatcttc aaggatctgt
     7321 gtgttgctct ccgcgtcaaa cttgtagacg cgtggcacag ccacctcaac ctcatcctgg
     7381 ctgcggctag tgatctggtc acgaacaacg cggaggatct ctgcttcgaa gaactaaggc
     7441 gacacagtac ctgttagttt gtacgctttc cacatccata acgcaatatc caaaagaaag
     7501 ggtgatcgct gcaattacac tcctataggt tgatagactc aacccctcta tgccggacag
     7561 atactcctct gcatgcttga caatgacagt cgtcgctccg tcgggcagag gacgggagag
     7621 cgttccccgg tagatgaaat tcatcaagcc tccattcaca cggctcagcg atgaacaggc
     7681 atactctgta caagataggc gatccaggat cagggcagcg atagggtcgc tttcccgctc
     7741 agtggtgccc attattgctg tatcctaaaa gttcattccg aaaataggct taggtatctt
     7801 tattcgggca aatgatgata ataacgatgg aatgatgatg catcccacac aaaaatttag
     7861 ccactgccta agcagttgat tgcgtttgaa gacgaataaa ttacctaccc cctgtgtctg
     7921 aatgggtgca caaagaacat tagggattag agtgccgccg cgtgcaactg tgtccccccc
     7981 ctaaccgtag caattttaca ctaaaaaaat acatatgtaa aaaagtcagt gtctcaaatt
     8041 ttattagctc ttatttattc tacttaaatt attttaaata tttacttgta tatataacta
     8101 tatatatatt gtaaaagttt atataaaata aatacttaaa tatataaagt aaaataaaat
     8161 tatatattat taatttattt aatttattta atttatttaa tttatttaat ttatttaatt
     8221 tatttaattt atttaattta tttaatttat ttaatttatt taatttattt aatttattta
     8281 atttatttaa tttatttaat ttatttaatt tatttaattt atttaattta tttaatttat
     8341 ttaatttatt taatttattt aatttattta atttatttaa tttatttaat ttatttaatt
     8401 tatttaattt atttaattta tttaatttat ttaatttatt taatttattt aatttattta
     8461 atttttaaat ttcatagtct ttaaaccttt acttttttaa gcctagtata gctatcttac
     8521 tatttttcaa atttgcatga gttattttgc tacagttttg gggggacaca gctgtgcggg
     8581 gcggcactct aacaagaggg gggggcgcga atctgagtaa tacaaacaac cacaaactga
     8641 agcatgacgg cccggagagc cacgagcaat taccccgatg taccccagca gaaggatctt
     8701 gggatatccc tgctcgtagc atcgagctag ccgaaacaga ttgctaaaga agttagtggt
     8761 gaaaacactt cgcaaggatt acacaccagc ccaccaatat aagtctgcca atcagaatat
     8821 tattagccct tacttagaac aagactttac aaaaagacca tcgtttatct agagtggaga
     8881 cccgggctgg gataggtttc tatcgcatga ggcttgtata catgtacgtg tcctgtctcg
     8941 attggcttgc gtttgaggca tttaactgag ttgagtggtg tatcttcatc tgcgggagag
     9001 gggtgtgagg gggaagcctc caaggggtgg aagaaaaaca cgggttgtga tcgagacctt
     9061 ctcagtgtaa cttcagtggt cgatgacccg tgttttttcg aattcacact acatggctaa
     9121 cctgttaatc acggtgatca aatagtggcg ggtccagagc cccttgtggc ccgactacgc
     9181 gagacgattg ctgcgtgtgt gtcgagagcg atgggtttgt agtttgatag cccccagaag
     9241 ccaggggcaa gcagttgaag ggatagtaag aaaatttaat gtcccaagtc gaagcatgtg
     9301 ggggtattgg cttgcatcat aataacttct atcaaaaacc ccttgtttcc tcggacggtc
     9361 aggaggaccg ctcgtagtca tcgggaatca gagagtgttc aaaatgtact atcgtgaaac
     9421 gatgctcgct tttgtaccct acctggccgt cttcgtggcc tgctatggtt tggtgtacta
     9481 tcgccggaag cgtcaacgcc tacccttgcc tccgggccct ccacagctac cgcttgttgg
     9541 aaacctgtat cagataccgg agatgaatcc gtggaggact tacagggagt ggcaccaaaa
     9601 gtacggcccc atcatcaccg tcaaatcggg cttgaccaac acaatcatac tgggctcgca
     9661 caaagcagcc agggatttgc tggacaagag aaacagaaac tatggttctc gtccgcactt
     9721 tatcctcatt ggtgacttta tctacggagg caatcaaact tcgttgctgc cgactggaca
     9781 acggtggaga atccatcgcc gaattctgtc ggcctttggc aatgtccgca catcccaacg
     9841 gtatcgaatc ctttacgatg ctgagtccaa gcggctccta cgggaaatcc tccacggggg
     9901 cgacttcttc gaaccttttc atcattattt tgttagaatc ctgttcgctc tgacgtatgg
     9961 taaaagggtg acgggttccc acgatccgga ggcccgcgac gtcatcgaga tcgtggatgt
    10021 ggtgttaaag gaagcgtcca ggagctccgt tccagaggcc ttcccaatcc tcaattccct
    10081 ccccggagcc ctggctccct ggaagcggcg tgcgcagttg ctctttgagc agcactcccg
    10141 actgttcgac aaccacatga acgccgcgtt ggcaaacaag ccgtggaact tttgcaagca
    10201 ggcgcttcgg ttgaaagcgt cgagcgaagt tgaccgagtg gaactcaact tcatccttgg
    10261 gagcataacc gaggccacac actctgggtc gatggtcctt ggagtcttca tcatggcgaa
    10321 catcctgcac ccggatgccg ttcgctgggt gcaggaagaa attgacagag ttatcgggcc
    10381 ggatcgcctc ccgtcctttg atgacatggc caagctgcca tatctgaatg cctatctcct
    10441 cgaggtcatg aggtggcggc ccatcactcc gggaggaatg ccccacgcga gctttcaaga
    10501 cgacgagtat atgggctacc acatccccaa aggcacgacg gtggtagcga atcattggtc
    10561 tatggacttt gatgaatccg tcttcacaga cccctatgag ttcaggccgc aacgctggat
    10621 agaagacccc aacctgccct ctattgcgtt tggattcggt acgcggattt gcccggggag
    10681 gcatattgcc gaaagctcta tctttatcgt cgctgctcgt ttgctatggt ctttcaactt
    10741 cgattatgcc tatgaagatg gtaagagaca ggagattgac tcatggaaca tgactcaggg
    10801 tctggattcg gggcccatgc ctttcaaggc ttcctttaag attcgtagcc ccaagcatca
    10861 ggaagtgatg gatagggagt gtggtgtttc tgatttggat attgatgcca tcctggataa
    10921 gattggtgcc gatttcctat gagtttttgt actattcttc atttgaacct atatagcaat
    10981 cattgtcttg gtgcagtaga ccacctagac cgcaagattg atgttggcag gggatcaggg
    11041 aaatcttaag caaagaatat tttaaagtcg cagtttaagt gtcagttagc tgatggtgaa
    11101 caattttatg tgtcaacgac tggctatcta cactatctag atggtagttg attgtaagta
    11161 taggtatata caaatgagag tgtgatgacg gccctcgatt cagtgatgac tggtgctgta
    11221 gggatcgttg tgtgattggt cggagcaagt gtattgtcac gtgactattg gttcaatcta
    11281 agtttagatc gtgacaggtg gattgttgat agcattccta atccactgaa tacaactgct
    11341 cctaaccatt tttcatttgg agtacacgtt ggcaaggcct tcgtaagcta cggaaaccta
    11401 cttagagagt tcccctctaa gttggcccta aaattctagg acagtaagat atacctcaat
    11461 aatagtataa atttcttagt aaataaaagt atcttttaca taataatata ttaagtgtta
    11521 ttacatatat ttaattaatt aagaatctta taacactttt atacttatta tgtatatgtt
    11581 atgtatttaa atataatata aatatattat gtattgactg tattttgata taagatctta
    11641 tatagcttat aagatactta atttcttatt taaaaaaaat tatataaata gttatatata
    11701 tatatatata tataagttca taatatttca aatgcattta ttttagctta tatttaaaga
    11761 gaaatcttga cttataaatt tctatattaa aaaatacctt tcttttctta ctagtctcac
    11821 tataatttaa gtatctatta aatgtcctag agggccaact tggaggggaa ctctctaggt
    11881 tggtttccgt agcttacgaa ggctgacgaa ggacccacca acgggtactc cttgtctcag
    11941 acaagacccc gcacatccca ctcgagcaca cactactttg gctgcccacg aatatccacc
    12001 acccggagct tcaaaggctc gacctgccag gtgccgtatt ccaaatagtc atacgggtcc
    12061 gcgttgcctg ggcatgcttc aaagtcaaag ttccatagca gacgtgacag gatcagacgt
    12121 agctgggtat tcgcgtggct gtcggaagaa agaaggggag aggagaagac atggttagtt
    12181 gtcgggttga gcaagaaggg gggatcccgc cctttggtct tggcgtactc acctcattcc
    12241 aatacagttc cgcacgccga tcgagtatgg gactgacgtg tctctgttat cagacgcaaa
    12301 ttctggatcg cctaaccagc gttcgggaat gaagcgaccc gcttctttcc aatgagacga
    12361 ggtgcgacag gcggcaaggt ttgcaacgga aatccacgtc taggagggtt agtgggccga
    12421 aattcaggtc agactaacaa gatctcttac ccccgcaggt acccattttc catcgatctc
    12481 tctgccgccc ttaggggtca gccgatggag gccgacagga atagttgggc gaatccggaa
    12541 ggcctctcga atgactgctt tgagatatgg caaggaagcg gaactcgcag cggtaatctc
    12601 agcctcgttg ctgaatgctt gtcgtacttc ggtcacggcc ttgtcgtagg cagctggatt
    12661 ggccgtcaaa tagtacatga tggccgaaag cgcagacgaa gtcgtctctc ccgccgcggt
    12721 agcaatgacg ttgatgttat cgaacaattc ctgctcgctc agggactcgg atgtgaaaga
    12781 aggaaggcta aactgatacg gctcggcctc cttggacctg gcctggagct tctcccgact
    12841 gacggctgaa tgaacgcgga agccgtctct aagacgggtc ggaatgagca agtactccag
    12901 gatcctgtgg tacggccgca atcggtgggc cgcctcaatg tacgttgact cgatgagcgc
    12961 cttgtaaccg gccatgaccc atgggtgata gtctccgttt agcaggcagt tcataccgct
    13021 cccaaacagc atatggctga gaatatccga tatgatgaag tgcgtccagg ggacaatgtc
    13081 gacaacaccg tcttgcgtgg ggaagtagcc tcttccgcag cgattgcgga gaccttggat
    13141 aagctggctg cagtattcct gcatcatggg cccctgtcct tgaattgtgc gttcggcgaa
    13201 cacgggcata atcaacctac ggtagcggtt gtgttgctgg cccgtcgcaa aaaacaggtt
    13261 gtcgctgtct ccggtctctt gtatgttagc gatcatgttc ttgtggaacg tgtcgtccgg
    13321 acccgggtta cccccgtaga tggtcctgat ggccgacgct gtgcggaaag acagctcatt
    13381 cggtccagtg cgcacgacgt ctccgtactt ctcatgcaat tcgtagaggt acttgcagtt
    13441 gatgccccgg atgatgtagt agacgttcac cagctgggtc gctgctgcga gccttgggcc
    13501 ggggaaccgg cgaaggggat gaaagaagac attgtacgtc ccgaggagga tgtggtaggt
    13561 cacccacttg agacgacgaa aagaaagcgt cagcggccat caattcacgg cattgggacc
    13621 acgatgccat cgactaactt accaagccca cgacgagacc ggcacgctgt aacagatcca
    13681 tgagccttgt cgttttatgt gtgagaacac aggttctgtg acattaactg ggaatggcgg
    13741 cctagagtgg aagtgagaat tatagactgg acggcgtgaa gtccggatct tggagtaaga
    13801 gggggaaggg aggtattaaa agcaccactc agttatccat gaatgttatc aggaaataca
    13861 atcatattgg ttagcagggc tcaccgggat taaccggata aataaataca taaatacata
    13921 aatgccctca tcgtctacgg cttagtctgc tggctggata ccacacctac taaatcccaa
    13981 cttaccccca ttgtctcaag caatagaatt gcgaatcact gtcgaccttg cgcacccagc
    14041 catactatat tgctacctct gacgacgaac catggacaat tcctcgcggc tattctcgcc
    14101 tctccgcctt gggaaatgtc aactgcgcca ccgtgtggcc atgtctccat tgacaagatt
    14161 ccgcgccgac gatttgtcgg ttcagatgcc ctttgccaaa gagtactatg cccagcgtgc
    14221 gtcagttcca gggacctttt tggtgtctga ggcgacctcc atatccaggg aatcagtagg
    14281 cttttccaac gtgccgggca tctggaacgc agagcaggtc cgggcatgga aggaaatcgc
    14341 cgacgacgtc cactgcaaag gttcctttct cttcctccag ctctgggcca cgggccgctc
    14401 tgctacacct gagaggctcc agagcggcga ttttgacttc gcatccagca gcgcagtgcc
    14461 catggagccg ggcggcgcag ttccacgcga attaacggag gaggatatcc acgatcttat
    14521 cgcaagattc gcagaagccg cgagaagagc catcgacgct gggatggatg gaatcgaact
    14581 tcacgcggcc aatggctacc ttatcgacca gttcacccaa gcatcgtgca atcaacgaac
    14641 agacagatgg ggtggcagca ttgaaaatag agcgaggttt gccattgaag taactcgaag
    14701 cgtggtagct gccgtcggtg cggatcgagt tggggtgaaa ttgtctccct gggggaaaat
    14761 ccagggcatg gggacgatgc aagatctcgt gccccaattc cagtaccttg tctccgagct
    14821 tcgtgacatg ggcctggcat atttgcggtt gtcaaactcg agatggattg acggggttcc
    14881 ccaagaggag gaagataaca gcatctacgt acacacatgg ggggcttcaa gaccagtctt
    14941 actggagggt ggctacgatc ctatttcagc gcaaaaagag gccgacatcc gttttaacgg
    15001 ttatgatgca gtcattgcat tcggtcgatt cttcatctcc aaccctgatc tccccttccg
    15061 aataaaggcg ggagttgatc ttcaaaagta caaccgggac accttttaca ctccgatatc
    15121 tgaaaagggc tatatagact acccctttag cactgcattc ttagaggagc atagttcgaa
    15181 ggcctctttg aagctctaag cttttagtat atgattggca tggccttaaa tcgttacatc
    15241 ataaaactac ctaatattag ataataagaa ggctctatct cttgtgagta ggtgtgtgtg
    15301 gacatcacat accaaagtgg aggcgccatt agtcctagtc taggagtaat gtattgagtt
    15361 attatcatta taattctcat tattcactat caaccttatg tcccttcata ctttcccatc
    15421 tgacttgcca cccctagaaa cgcctcgtca aagtattgct cccttatctt ggcagcgctt
    15481 cgtaactata ttactacatc atcggcacct aagcttccac tgtcgagagc tgaaccgcat
    15541 tgtcccctcc cgattccctg caaagtggtg cctaagactt accaccatcc ggcaagatga
    15601 acccgccacc gtctctcctt gacaaggccg ccatcgtcac aggggggtcg cgcggtatag
    15661 gagctgcgat cgccattgag ctggctcggc gtggagccca cgtcttaatc acatacaaca
    15721 cagctagcca caaagctcag ctagtggccg aggagatcca gaaactcggc cgcaaagcca
    15781 ccgttgtcca agccagtagc actgatcgag aggggccaaa ccgcattgtc caagccgccg
    15841 taagccagta cggccgaatt gacatcattg ttaacaatgc gggcatggcc gatgactgcc
    15901 tcctgcagga cctcacgcac gagttttggg acaggatcat ggacgttaac ctccgtctcc
    15961 cggcgtttct ggtgcaggca gccctgcaac acctggggcc agcgccacgc atcgtcaaca
    16021 tctcgagcct ggctgctcgc gcaggataca atgccacgtc agtgtatgcc gcctccaagg
    16081 cggcacttga ggggatgacc cgcgcatggg ctacggagct cgggcatcgt tacaacgtca
    16141 cagtaaactg tgtgaatccc ggtccagtgg ataccgacat catggcggtg gatgagaaca
    16201 cggatgcgga agtggtggcg tactggaacg ccaaggtcaa agagacgcca gcggcaccta
    16261 gggtgggaac cccgggtgac attgcccaga ttgtggcttt cctctgtgaa gaaggtagcc
    16321 gctggtgtac aggcagtgtg gttaatgcta atggtggctt ggttactgtt tgagacagag
    16381 gatctgcggc agatcgcgga aggtttcgta ggttattgaa gtggttggtg ttgttttatt
    16441 taggttagta tataaatata gatatatgta tatgtatatc ttatttaagt aatagtatac
    16501 tttatgtact tttaagaaac ataatagctt ttgaactatt atataataat tattttatta
    16561 ttttatttta aatatataaa attaatttat aatattataa cttattaata atctagtttt
    16621 aattaccttt tataggccta attacttgtt taaaagtaat taattaatta ttacaaagtc
    16681 ttataatttt ttatacttaa agtatttaat attctaatat tgtttttata tttactataa
    16741 tttaattata ataatatata attgttatat atatatatat atatatatat atattattat
    16801 aactaaatta tagtaaatat aaaaagtagt aaaatattaa aataatttaa gtataaaaag
    16861 attatagaac ttaaaggcaa ttaattaata actttataaa aagtattaat taattttatt
    16921 aaactttaaa aaactattgt ttaaaagaat tattatttat ttataataac tttttagcta
    16981 ttatataata atagttttct taagcttaag tcttataata cagtctactc tatttaacat
    17041 tacgagtttt ttacttaatt atttagtaat tatttcctat aataaaaata tttaaaatat
    17101 aaattataaa agattttttt taaataataa agttaatatt gccttaatat aaatatatta
    17161 tatattatta aatttgtttt taatagtata ttattatatt atattatttt aaccctataa
    17221 tgtttattaa tttaactaat tcaagttata aaatatttat atttattata aacttttcct
    17281 tttttacact atattattta gtttaaatct tgactatacc tattaactat atttatataa
    17341 tttataattt aactattagt tattaacttt atttatttta tcttaattgc cttaaacata
    17401 aaacataaaa cttttattta aaaaatatat tttaatattt ttaaaagtaa taattactct
    17461 taatttatat aagtataata ataccttagt aataaatcac taaataagta aaattaaaac
    17521 ctaagtattg tattatatat aataagttaa attttataca attgactatt atacaatgca
    17581 tgtataatat atatataata acactataca ttaattatat tatatatttt aacgctttta
    17641 aaaacagtgt tataatgaac ttttaatata tttttttaac ttgcctttca aaagcttagt
    17701 ctatataatt tattagtatt taactagtct taatcttaaa ttatacaaag cttaatcctt
    17761 agaaaaatag catataaagt aagtccattg agactataag acagcagagc ttatgcaagg
    17821 tcggctctgt atgcaagtac actaattttc gtaagaaggt aagagaccta aacaatgcaa
    17881 gggcgacgtt aatgagcttg tgtaacctcc tcactgactc tttcaacttc catccactct
    17941 catgccacag cactcttagt ttgggttaat ttacgatgca gagagtgagg ctagttgcga
    18001 tggtcctgcg gtaaagttga ttttctagct cagtggcgag attaataggc gcatctctag
    18061 gccatgcaac gaacttttgt cctccatata gagataagag tttactagac gagttagaca
    18121 tgatcttgcc ggtaagaaat tagcagaata tggcctaata ttaactaggg tgcgaccccg
    18181 ggtaactgta ttcccctggc aactatgcga gttatacaca aaaacatata gtttttaaat
    18241 agctataagt cagttatttt aagtttaagt agactagtgt gttaagtttt ataaggttta
    18301 aaaatgatat tattttattg tgttttaaga ttattaatag aatatataaa taatataata
    18361 cataattata aaatattaag tttataaaga atatgatatt tatatttttt tatttaatta
    18421 atatataaaa aataaataca aataataaaa ttatattcat ttagtataag tattatattt
    18481 agataaggtt taaattaaat aacatagtaa aataaaaaga atattcataa taaatataat
    18541 tattttataa ctagtattag ttaaatcaaa taatattata taaccaaagc tatataatat
    18601 aataatattc tattaaaggg gtttaaatat atataatatg cttatactaa aatagtattt
    18661 atataattat tttaaaaaaa acttattatt tatatataaa attctttata atttatacgt
    18721 taaaaatttt aaaaactatg cataaattaa ttatagtatt tagtctttta tatagcgcta
    18781 aataaaaggt attaaatata aaaaccttgt ttttattaaa tattattatt ttaaaataat
    18841 aattgtatta ttattaaggt ttataaaaaa tagcttttaa tagtttagtt taactaaaag
    18901 tcttagattt aaataaaaag ttatttaatt taagtaaaat tatatatatt aaatatttta
    18961 ttattattct tataagaata tataagtaac atatataagt tatagttaaa tatatagata
    19021 aaattatata aatatatata atgtaaaaag cttaaaaaaa aataagtaaa taaaggtaaa
    19081 tgtattaaaa agctttaatt ttatatgatt ttataatata taatagtata ttatttttat
    19141 aagaatataa acttatatta atttatgtat atatttatta tatacttaac ttatttatat
    19201 aatatgtaaa tttaaattta atattattat tttatttcat attttaaaag tcttttttaa
    19261 gtatcatata aaaatatatt atatataata ttaaatatat aaaatttatt aaattatata
    19321 agattttaat attattatat ataaaactaa aatcttatag aatttattta atatttttca
    19381 atgttaatta taaattcaat aacatttata taaaagttta aaaaagtcta tatttgttta
    19441 ttaatatagt aaatatagaa acatactttt tacactctat aaatctttaa acctaagttt
    19501 aattaggctt aaaataactg acttatagct attcaaaaac catgtgtttt agggccagat
    19561 cggccagagg attagcataa acttttgaga gatgtggggc aaaaaaagaa tagcacaggg
    19621 ctcggtttct ccttttagac caagacctgt actaatctct taccaaaaag ttatgcaaat
    19681 tttcgaatgt atcttttttt cgctttacct atctgatcct agtggcttgg caactattcc
    19741 ctattaagcg agtaccttca ctttttttct attgtttctt attccttcta aaagtaggat
    19801 tatcttattc ctcgagtggt ttttctgaac gaagacccta accctttgcc atataaccct
    19861 aaccctctct tccataaccc taacccgtat tcctatcagg aaggtggtct ggccggattg
    19921 cataattact gccgtagtac attcaggccg gttatgcaag ccaaaagtca ctgtggggca
    19981 acagaggatt ggcataatcc tctggccgat ctggccctta gtgtaaaact cgcatagttg
    20041 cgggggaata cggttgcccg gggtcgctcc ctagatgcga gttcttccaa aagaagatca
    20101 gtgctccccc tcgctgagct tatagtgcgt ttgtagaaca gtcagaaccc ctcacgaaga
    20161 tccaccttcg ggattttatt catatgcaag cttccactgt cctggactag gcagtaagaa
    20221 ctcggtccgg ggtccgggtc tggagggccg ttgtaacccg aaaacgaaac cttttaaacg
    20281 cccactcatt ctctccggta ttgcatgagg atttgttggg gaaatcaggc cattatgcgc
    20341 agcgggggtt gtcgattggc gtggtccgct gcttatcctt gtgtttaatt ggctttctcc
    20401 ctatactctc ccatcgtagc ttaatgcatg tgtcaatact tacctactaa aggctaagga
    20461 ggcgtgcgtt acacagccaa tcatgcttct tagctagtag tcgtatgata gtaagcctat
    20521 cttcagcttg aagagtccga gatagtagtc ctaaacggtc tgagatatgc ccttgtgcat
    20581 aacagtggaa ggccccgttt cctttagggt taagtagacg cgcgataaga gtgtgccttc
    20641 cgggatctgt tgcaatgggc cacagtgggt ctcttgttcc ctagcattga gcaacgcgtc
    20701 cttagctccc gtcttctgtg ccttcttgaa ataacgcttt ttttagcctc tcatgcggtg
    20761 ggggaaaaaa acacaggtct ttgatcgaca cttttcagtg taagctcagt ggttaacgac
    20821 ccgtgttttt cttctacccc ttacctctgc atgccatagt agctctgaaa gcccccatgg
    20881 ctagctgcta aggcaggtag cccttgcagg agggtatggg gtggctctat attagtaata
    20941 gtcgtgaatg acgctacaga agcctctggc caatggactt cttcacatga caatctgtat
    21001 gcacggggta ttaattctac tagcttgcgt gggcgttgtt taacactcta cttcttgtgt
    21061 gtcttagggc actctaaaaa tactaattat tcttctatta aggaagactt agtaagcccg
    21121 cagttttaag caaatgtgct ttgactagtt aaaatttgta acgagactac ctagcgagag
    21181 cgtatctaca cgcgcttacg tgatgctaga gtctcggtgg gcttgcgatt acggatcgct
    21241 gtgtacaaca tttagatttc cctaagctta agtcttgaag tacagtctac tctacttaat
    21301 attattattt ccttttaata aattttctta attttattta ttaattaagt atatattatt
    21361 tatttaaata aacaaaaaaa tctttataag ctttttatat aaaatttaat atactactaa
    21421 taaataatta ataattaaaa actatattta tttatacttt agtttgtatt tatactttat
    21481 taaaagtctt aacgtacttg ttaaattatt ttcgcaaaaa gttaaattat aaaacacttt
    21541 ttaactagct tactaaagta ataattaaag ttaataataa aaatctattt aataactcat
    21601 tagcaaaaaa taagaaattt ttatacatta aagctataat aatatatatt aatacagacc
    21661 aaggtaagca gaattattaa gtgtttacgg tatttaggct ggcctgtctc tgtttgagcc
    21721 tgggctagga cgtggagaaa actaatgtgc caagcagtgc tgtcgtagac gaatccaatc
    21781 aatacaacag gaaagcagta gtggagtcgg gattatcggg agataatgtt tacggaatcg
    21841 ataaggttga gaatggggtg tggctaatag ggttggtatt agtaaagcag tgtgaaatat
    21901 cgatcgctag cttttggccg ttgctagagg agcggcacaa ccaatttctc tccccgacgc
    21961 agcgcaggcg gaaggggaca gtacagcttt tgatctacct gggtaggata catccagtct
    22021 ccggtctgat aagcctcaat ggtatagcat tgcgtgtgcc ttgtcaaagt acatctcatg
    22081 gatgtaaccg gatggccatg tgttatttgc tgcatcgtcc gtctttgagt tagtcctgct
    22141 gtaaatcctg gtataaaaac aagagtcttt gcaaggagta tgcccctaga tgtttatgtc
    22201 attagttttg gctgagattt tccatcgtat ccctttttgt tacccctcta gcttatcttt
    22261 ggatgacttg cgctttatct gattgctcgt acaagtgttc catgactacc taggcagatt
    22321 catatttacc tgatgatcct tctttacaca tatctctggc ctcatcatca catttgaccc
    22381 tgccacacac cagcaatgcc gtcccatacc ttcaacccgc aagcgggata tgatttggcg
    22441 gttgatcgca atcttggcct cggcgagatc ttctataaca gggctcagaa gtctcatcag
    22501 gccattgccg tttgtgacgg aggagctgtt cttacctacg gacagctaca tgctaaagcc
    22561 taccgtttgg ctcaagagct atctcaatgg ttgcgcctca ccgagaagcc cgtgggaatt
    22621 gtcgtgcagc atggaatggc cgacgtagtg gcccagatgg ccgttatcta tgccggtggc
    22681 agctgcgctc ccatggatcc tacactccct gacaatcaga ttcaaggacg gttaaaacgg
    22741 ctggatgctg tgtgtgtctt gactgatcag gccaaccgac atcgtgacct tggcgctgat
    22801 gttctctgca tcgacgactt tgatatagcc gacttggccc ctgaagacac actatacccg
    22861 gttgccacta atctcgagca ttgtgcatac ctcatccata cctctggaac tacagccgaa
    22921 ccaaaggccg tgcagatcgc ggctaggtcc atactacatg tagccttcta tgcccccttg
    22981 gagccggtgt atgacaccga tgtggtggcc cacgcaaata acagcagttt tgatgtgtct
    23041 ctttttgaca tctgggtacc gttgctgcgt ggtgcccaga ttgccgtcat caacaaggcc
    23101 gtcttgttgg atccacccat gatggctcgg gagattgatc gcctgggcat cacggttatg
    23161 gctactacca ctgcggtact taatctcgcg gctttcatat accccaaagc ctttgcaaag
    23221 ttgcgccttg tcactattgg cggcgaggct gcaaacgtcg ccgccatcag aatcattctc
    23281 aaaaatggcc cccctgcaat gctcttcaat gcgtatggac cgactgagtg ctgcgttttc
    23341 tgcttggctc atcagatcac ccctgcagat gtcgaacatg gctctatagg tgtaagcatt
    23401 ggcaaacccg tcggccgtac tatcacgtat atcgctgggg atgaaggggg ggagagtgat
    23461 caaggggagc tctggattgg aggccctggg gtgtctccgg gttattttag gcaacccgaa
    23521 aagaacctcg ccgccttttc cgaccttggt gaagcgatga cttccctcga aaatccggtt
    23581 cgcttctatc gaacggggga tatcgttagg cgccgtccta acggcgcgct tgagtacgtc
    23641 ggtcgtcggg atcaccaggt taaagtccga ggatttcgca tcgaactgga agctgttgaa
    23701 gcgggcttgc taaagacggg cctgttttcc gatgccgttg cgatgaggat agagatgcct
    23761 caaaacggag ctggctcgat tctggccgcc tatgtcgtgc ccacggatgt atccaagccc
    23821 cctaccatgg atgaggcatt ggaatctgcc aagtccatcc ttcctcatta catggtgcct
    23881 caattagagc tagtgccccg attgcccttg aacagacacc tcaaggttga tcgtaagcag
    23941 ctggcagagc tctttggtcg acgatgggag gacgtctccc cggcgcaacc ggagaatgca
    24001 tcacaagatg tccgctctgc gttggtaagt ctctgggcca cggtattggc atcaccattg
    24061 tctacgtacg gggatgacga cgatttcctc cacctcggcg gcacatccct ccaggcagct
    24121 atgctcataa atcaaatccg gcacaaattt gacatagagg tctcacttct cacactatac
    24181 gacaatacca cgctaggagc actcacctcc attatcaagc agcgtctgag cggccagtca
    24241 gagaccttgc ataacgagaa ggatagctgg gtagccgata gtgagatcgc tgatgacttg
    24301 tcctgcccgt tagacaggcc gattgactgg tgtcgggata ccgaagggag agtctttctt
    24361 acgggcggga ccggctttgt cggcgccttt ctgctcgccg atctcctaca catgccgcag
    24421 acttcccagg tcagatgtct ggtacgagca actgacgcgg cggtcggcca ggagcgtcta
    24481 cgagcggccc ttgacaagta tggcctctgg gaggatggtt tcgcggacaa gctcgtggcc
    24541 atcgctggcc ttctcgaaga tgactacctg ggcatgggcc gcgagcagtt cgaggaggct
    24601 gcctcttggg ccagtgttgt attccatctt ggagcccgtg taaactacgc tcagccgtat
    24661 tcgctgcatc gcgcctcaaa cacactgggc acacggaaca tggtacgatt tgcctgcgcc
    24721 ggccgtacca aggccattca ctacgtgtct agcattggct gctttgggcc cactggaagc
    24781 attctgggga cgaccagtgt gcgggaggac gagcctctgt tgcctcacat tactgcgttg
    24841 ccatatgatc atggctatgc tcagagtcaa tgggttgctg atgcgctgtt gcgacggctc
    24901 atggatcggg ggtttcccat tgccatctac cgaccaggct tcatcgtcgg ccacagccag
    24961 acgggtgcct gcaaccccga tgacttctta tctcgtctca tcgatgcctg tcgtgagatc
    25021 ggatgctacc cccagctccc caaccagcgc aaggagtttg tgccggtgga ctatgtcaat
    25081 gccgccatcc tgcatatcgc tgcgtcccct gcatccctgg gtcacgctta tcacattgtt
    25141 ccccctaccc gagctgtatc tatcgacatg gataactcga tggctctagt cgacagggct
    25201 gggaactcgc ctatgcgtcc cgtgtcctac aaggaatggg tagagaggct ggcggctact
    25261 tcgcctaaac gcctgcttcc actccagccc atgctagcgg aaagggtgaa ggacggactc
    25321 actcgctggg agttgtatga gaacatgcct gtgtatgaga cgacgaacac ggctcgggcg
    25381 ttgcagaatt atccgggggg gttgcaattc ccggttttgg atacttcatt gatgaagagg
    25441 taccttgact ttctagaggc aaagggttag aaaatgcaag tataatttga accggtagtc
    25501 caatccatag attacgcgct cgttacctag ttgtggccgg agagaaaaac aagaagccag
    25561 ggtcatatca tagacgtgaa ttgcgcattc attttatcac acatgacgct agtacaacac
    25621 tactatatag agtatcctat tatccacaga taatacacat tatttctccg tagcgaaatg
    25681 cttgcggaaa aagtcctttg tgcggagcgt gtgttgctct ggctctggtt ttcccaatgc
    25741 cactgctgtg gttcgtttta attccgctgc cgtatcagct tcgctaggct caggagcaaa
    25801 atagcggcct ccggtggttt gtgtaaaggc aaacatgagc tttacgtcct ccagctccgg
    25861 aatcccgtgg atgtcaaacg cttcccatga cggtaaaacc ggttcatacc gacacttctt
    25921 tccggttact accgagttgt aagcaaaggt cccttccccc cgtatatcct gcatttcacg
    25981 agcaagaaga aaagtaatgg tgtaatcctt accttgctcg aagtcagcga ccagctcgtc
    26041 gaagccacgc agctggctca caccgtggat gacacggcca ttatatcgtt ctgggttgag
    26101 gaatatgccg tggataatat ctccaaagtc atcacgtatg cctaagaagg gaacccggtt
    26161 atccccgccg gggcccgccc aatggggcac ccgaaaggta aggtatccct cctcatcggg
    26221 gaagtacgga aatccgccaa atatcggggc gacctcctcg gcaaggaagt tctccagata
    26281 ccaggccgga ttgatgggtg taagagtctc gaatgaaccg agcttcctgg catactgctc
    26341 gatcttgtac ttcactatct gccagtcagt atcatgtaag gagtgcaggc agctttcttt
    26401 gagtacagac tttccatggc cttcatattc accttgccgc cagtcatctc gacgcatgga
    26461 gggcccgagc taaagaccaa atgcttcacg cccgccccag cggccgcgtc aacaatcgtc
    26521 tttcccaggt cgaactcggt gggaccaccg ggctgcctcc aaatcggatc atccgagttg
    26581 aggttgacaa atgctcccca ggcaccctgg aaggctgcca gcatctcctc accattaaag
    26641 ccatccgcct tgacgacctc agcaccggcc gagagcaagg agcggctagc ttgggaatcg
    26701 gggctccgtg tgatagcacg cacgctgaag gatgggttct gaacgaggga tctggccacg
    26761 gagccaccct ggttaccagt agcaccaaca accgcgatga taaaagtcat tgtgatgagt
    26821 acaagaggcg caaggtaaac taactagggg ggaggtgtat gtgtgccaat ggggactgac
    26881 tttatagaga gaagtctacc tagataaaga gcgggggaat gcaagtgttt taagtagaag
    26941 agtgtaaagg ataagagaca gtgaataaat agcgagggaa aatcaggtat acttattatt
    27001 acattagtct tatgacttaa ctatataact taatgaattc gaaattatat tattaatagc
    27061 tataaaagag tttaagaaag aatttataaa aatccttttt aaaaagattt attctaggct
    27121 taattcttaa atactaactt ttattttcta ttttattacc cgttggtggg accttcatta
    27181 gccttcgtaa gctacggaaa ccaacttaga gagttcccct ctaagttggc cctaaaattc
    27241 taggacagtt aaaagatact taaattatgg tataattaat aataataaaa agtacctttt
    27301 aatataaata tttaaaaatt aaaatttctt ttcgaatata aattaaaaat aaatgcattt
    27361 aaaatattat agttttataa atataaaaat accatttaca taattttatt tcatttcaac
    27421 taaaacttaa atgttttata agtaatatta tgttttatac caaaatataa tgtaaatact
    27481 atatatttat cttataatat aaataatata tattatataa agaatgaaaa ttatataaat
    27541 aataaatata aaactattat aaatctttaa ttaattaact ataataatta taaaaccagt
    27601 tattaaatat aaaaaataag aaataatatt tttatattaa tttatattta atatactaaa
    27661 tcttttatta tagcgtataa aaattaaaat aataaattat tatataaaaa ctacttttat
    27721 ttactaagaa agttatacta ttaatagggt atatcttact gtcctagaat tttagggcta
    27781 acttagaggg gaactctcta agttggtttc cgtagcttat gaaggtcttg ccaacgggta
    27841 ctttatactt gttctttatt cattttctta cccatggttt tttctttctt tctattagca
    27901 taactgtcac tatagggtta gggttatcca ctgtacatac cccctgggta taggtgtaat
    27961 acagttagat gacgaaacta tgaggtcatt ttccctaaca ctacgacgga tctatgggcg
    28021 tagacctttg tcaccttatt gtacactaaa ccctattttt cccgaattta aaacaagtac
    28081 agttatagcc ttctatatct aatcctgttc tttaagttct tccgtgttaa tctcatgcaa
    28141 tctctgtcag tgatagacta taacattggc gctaaggcgt aaccctagtg ttgacgagcg
    28201 cgacctccac tagctcaagc ccataataca cattccttcc tcatggttgc ttgtctccat
    28261 aactactcgt cgttgccgta gtttttcctg tgataagcag tgcagataaa acgcggggct
    28321 caaatccatc gaattttttt ctctcgcttc gttgccatcc aaggctaccc ctccaccagt
    28381 ctatcgttcg attccagagg tagtatcatc gaatccaacc atcccatccc atcaagatgt
    28441 gcggtgttct cgccctcatc ctggcgaatc agtcgtcgtc cgccgccaac gatctacacg
    28501 aggcgctata tgtgctccag cgtacgtagt gataaagtct cctacctcat gtccacgatt
    28561 gggataccta cagctaaccg acattatcct ctcctctata gaccgcggtc aagatgctgc
    28621 cggtattgcc acctcaacgt ccagtggtca catccacatc cgcaagaaga atggcatggc
    28681 agccgatgtt ttccagtccg gggcccggtt ggcgaatctg tttggcagca tgggcattgc
    28741 tcacctgcgt tatcccaccg ccggcggcag cgcaaacaca gaggctcaac cgttttatgt
    28801 caacagcccg tatggcatct gtttcgccca taacggtaac ctgatcaaca cggtggaact
    28861 gaggcgctat ttggatttcg aaatccaccg gcacatcaac tcggatagcg acagcgagct
    28921 gatgctcaat atcttcgccg atgagctcag tgagacaaag aaggctcgtg tcaacaccga
    28981 ggacatattc aacggcttga gcaaaatgta ccaacgatgc gagggcgcgt gggcatgcac
    29041 ggcaatgctt gctggctttg gcgtcatcgg attccgcgat gcgtacggga ttcgccctct
    29101 ggtgatggga tctaggccct cgtcagatgg agatgggttg gattatatga ttgcttccga
    29161 atcgatcgcc ttggaccgcc tgggcttcac caacgtccgc gacatccagc cgggggaggc
    29221 cgtcattgtc gccaagggag ccgaacccgt cttctgccag gttgcgccca ggaagagcta
    29281 caccccagat ctttttgagt acgtttactt tgctcgtccg gattcggtca tcgacggcat
    29341 cagtgtctat cagagccgtc aacgcatggg acgttatctt gcagctagac tcctggaagt
    29401 actcggacca gaaggcatca aggaaattga cgtcgtcatc ccagtccccg aaacgtcatc
    29461 gcccgcagcc gccagcgtcg cccacgctct caacaagccc tactgtgccg gctacattcg
    29521 gaacccctac gtcttccgaa ccttcatcat gccggggcag gcaacgcgcc agaagggagt
    29581 ccgtcggaag ctcagcgccg tcaaggaaga attcaaaaac cggactattc ttctagttga
    29641 tgacagcatc gcgcgaggga caaccagccg cgaggcgatt agtatggcgc gggaggcagg
    29701 cgtaaaaaag atcatcgccg cctgttgttc ccctgaaatt acgtaagtcc aggatccatg
    29761 ctcccccggc cactccttga tcctcttcct ttgactcatg ttctctttag ctatccccac
    29821 atctacggca tcgatctgcc ctcgccacat gagatggtag cttacgagcg ggataataac
    29881 gacatcgcgc aaaatctcgg agctgataga attgtctacc agacccttga ggacctgcaa
    29941 gcgtcctgcg cagagatcgc cagggaaaat gacttccaag aaccacacac attcgagaac
    30001 ggcgtgttca gtggtcaata cgttaccccg gtcccagagg gctactttgc cctgctggag
    30061 aagatccgag gcacaggccg gaaagaggct ttagacaaga gttccaagcg attgtag
//
