BGC0002146 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002146 (Cladobotryum sp)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	30,117	FR901483	NRPS:Type I	100%

BGC0002146 - Region 1 - NRPS-like

Download region GenBank file

Download region SVG

Location: 1 - 30,117 nt. (total: 30,117 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 30,118
Label		BGC0002146

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002146	0.96	NRP	FR901483	Cladobotryum sp.
BGC0001893	0.33	Other	abscisic acid	Botrytis cinerea B05.10
BGC0001528	0.32	Terpene	betaestacin	Phoma betae
BGC0001267	0.32	Terpene	lysergic acid, elymoclavine	Claviceps fusiformis
BGC0000798	0.32	Saccharide	dhurrin	Sorghum bicolor
BGC0001516	0.31	NRP	aspergillic acid	Aspergillus flavus NRRL3357
BGC0002582	0.31	NRP	guanipiperazine A, guanipiperazine B	Streptomyces chrestomyceticus
BGC0002602	0.31	Alkaloid	aspergillic acid	Aspergillus flavus
BGC0002670	0.28	Other	fosfonochlorin	Fusarium oxysporum f. sp. lycopersici 4287
BGC0002207	0.28	Other	psilocybin	Psilocybe cyanescens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002146	1.00	NRP	FR901483	Cladobotryum sp.
BGC0001893	0.66	Other	abscisic acid	Botrytis cinerea B05.10
BGC0001528	0.65	Terpene	betaestacin	Phoma betae
BGC0001267	0.65	Terpene	lysergic acid, elymoclavine	Claviceps fusiformis
BGC0000798	0.65	Saccharide	dhurrin	Sorghum bicolor
BGC0001516	0.64	NRP	aspergillic acid	Aspergillus flavus NRRL3357
BGC0002582	0.64	NRP	guanipiperazine A, guanipiperazine B	Streptomyces chrestomyceticus
BGC0002602	0.64	Alkaloid	aspergillic acid	Aspergillus flavus
BGC0002670	0.61	Other	fosfonochlorin	Fusarium oxysporum f. sp. lycopersici 4287
BGC0002207	0.61	Other	psilocybin	Psilocybe cyanescens

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 2395 - 30117:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

QQO98485.1

Search NORINE for peptide: strict or relaxed

AMP-binding (27..425): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: ala (Ala)

Stachelhaus prediction details:

Stachelhaus sequence:: DVFATGAVFK
Nearest Stachelhaus code(s):: Phe DVFALGAVYK (71% 8Å match); Ac-OH-Orn DVFALGAVNK (38% 8Å match)
Stachelhaus code match:: 80% (moderate)