BGC0002155 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002155 (Pyricularia oryzae 70-15)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS	1	49,698	High	nectriapyrone C/nectriapyrone D/nectriapyrone	PKS

BGC0002155 - Region 1 - T1PKS

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Location: 1 - 49,698 nt. (total: 49,698 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 49,699
Label		BGC0002155

Tailoring functions

Ligases: synthase

MGG_00806: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002155.3	0.98	PKS	nectriapyrone C, nectriapyrone D, nectriapyrone	Pyricularia oryzae 70-15
BGC0002191.2	0.75	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001254.3	0.64	PKS	ACT-Toxin II	Alternaria alternata
BGC0002192.3	0.63	PKS	FR901512	fungal sp. No.14919
BGC0001606.3	0.63	PKS	gibepyrone-A	Fusarium fujikuroi IMI 58289
BGC0001268.4	0.60	NRPS, PKS	fusarin C	Fusarium fujikuroi
BGC0002240.3	0.50	PKS	BAB, BAA	Metarhizium anisopliae
BGC0002171.2	0.48	NRPS, PKS	pyrophen, campyrone B	Aspergillus niger ATCC 1015
BGC0002275.2	0.48	NRPS, PKS	pyrophen, campyrone B	Aspergillus niger CBS 101883
BGC0002525.3	0.47	PKS	fusarubin, 1233A, 1233B, NG-391, lucilactaene	Fusarium sp.

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002155.3	0.98	PKS	nectriapyrone C, nectriapyrone D, nectriapyrone	Pyricularia oryzae 70-15
BGC0002191.2	0.75	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001254.3	0.64	PKS	ACT-Toxin II	Alternaria alternata
BGC0002192.3	0.63	PKS	FR901512	fungal sp. No.14919
BGC0001606.3	0.63	PKS	gibepyrone-A	Fusarium fujikuroi IMI 58289
BGC0001268.4	0.60	NRPS, PKS	fusarin C	Fusarium fujikuroi
BGC0002240.3	0.50	PKS	BAB, BAA	Metarhizium anisopliae
BGC0002171.2	0.48	NRPS, PKS	pyrophen, campyrone B	Aspergillus niger ATCC 1015
BGC0002275.2	0.48	NRPS, PKS	pyrophen, campyrone B	Aspergillus niger CBS 101883
BGC0002525.3	0.47	PKS	fusarubin, 1233A, 1233B, NG-391, lucilactaene	Fusarium sp.

Similar known clusters from MIBiG 4.0

Module view

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Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 49698:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

MGG_00806: pk

PKS_AT (699..1042): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 81.0
Methoxymalonyl-CoA: 70.6
Malonyl-CoA: 47.6
Propionyl-CoA: 46.2
Ethylmalonyl-CoA: 37.7
2-Methylbutyryl-CoA: 36.1
CHC-CoA: 34.7
Isobutyryl-CoA: 31.4
fatty_acid: 30.1
trans-1,2-CPDA: 25.5
Benzoyl-CoA: 14.1
3-Methylbutyryl-CoA: 5.6
inactive: 0.0
Acetyl-CoA: 0.0

Link to PARAS substrate predictor