LOCUS       BGC0002157             15246 bp    DNA     linear   PLN 02-FEB-2021
DEFINITION  Aspergillus flavus strain NRRL 3357 chromosome 4.
ACCESSION   BGC0002157
VERSION     BGC0002157
KEYWORDS    .
SOURCE      Aspergillus flavus
  ORGANISM  Aspergillus flavus
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 07:24:49
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15246
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15246
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[6451:14413]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6452..14413
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..15246
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..15246
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002157"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..15246
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            join(117..620,684..821,910..997,1052..1120,1172..1810,
                     1873..2434)
                     /gene="dtpC"
                     /locus_tag="F9C07_2283792"
                     /product="cytochrome P450"
     gene            117..2434
                     /gene="dtpC"
                     /locus_tag="F9C07_2283792"
     CDS             join(369..620,684..821,910..997,1052..1120,1172..1810,
                     1873..2285)
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="JGIDB:Aspfl2_3_2283792"
                     /gene="dtpC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 85.1; E-value: 8.2e-26)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="F9C07_2283792"
                     /note="GO_function: GO:5506; oxidoreductase activity,
                     acting on paired donors, with incorporation or reduction of
                     molecular oxygen - iron ion binding [Evidence 20037] [PMID
                     16705]; GO_process: GO:55114 - oxidation reduction"
                     /product="cytochrome P450"
                     /protein_id="QRD90551.1"
                     /sec_met_domain="p450 (E-value: 4.5e-29, bitscore: 89.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MDTMFSEALSRAVLHAPTVGVIATLSLIASFLIIFVSDLIHCGFK
                     TWAVRWAPCIAGKSLLSERFRLKKSMEDYYEEFADAYRKYSKNGKAFSISDNIGEGYIV
                     MLPPQHYHDWYNVPRDHLNWGKAVNQEFSLDDLGIDLGWHIAPLTVQKCSQVDFIKRVE
                     GPIGRELDRLLVENLTESKEWHLCSLFNTVVNIYSHIALLVVLGPEFSNHTALAEQLPL
                     FNMQLSDRMGSEKSYPMFFKPLVRKFSAKTRQVQSIMAEMKKTIVPEIRRRVEQRRRST
                     KQSTQNCFLDVMIELLLKKGLLSHDAVKDDERHFDTMAIQTIFLLFEVLGGLTPATTSS
                     LYQIMKTPEYLAPLREELAAALKQADNAWSFDIFKHTPKLESFTKECLRVFTPSGIASG
                     GLVEKPLQLRSTGRTLSPGTKFSLPAQQAHLDPDNYPNPNIFDGYRFCDPQSGACDIRG
                     TITPSAKWLIFGIGTSACPARLLATRISQTLFFKVLRKYDLRLKLDNGQPEVVYAATNM
                     FVNFNTQMYVKSASI"
     mRNA            join(3913..4397,4447..5159,5220..6066)
                     /gene="dtpB"
                     /locus_tag="F9C07_1580830"
                     /product="dtpB"
     gene            3913..6066
                     /gene="dtpB"
                     /locus_tag="F9C07_1580830"
     CDS             join(4078..4397,4447..5159,5220..5248)
                     /codon_start=1
                     /db_xref="InterPro:IPR019257"
                     /db_xref="JGIDB:Aspfl2_3_1580830"
                     /gene="dtpB"
                     /locus_tag="F9C07_1580830"
                     /product="dtpB"
                     /protein_id="QRD90552.1"
                     /transl_table=1
                     /translation="MVKNNAGIVNMFEKRRTQTTTIPIIEIMREKRSEDLETEIVQGLQ
                     FDSLQLPQELLWDDAGQILFDDLCNSSTYYLTKKEKEILQKYSTDMAATIPEGSTLIEL
                     GCGSLRKTGILLSALEKSHKAVTYYALDVSQDSLENGLAQLHKGLGCLDHVELRGLWGT
                     YEDAIAWLADQHPINVHNGITFLWMGNSMTNMHLAQAQSLLSRMTKTCIGSGIPCQILV
                     SVDSCSAEDIVMGAYDTDSQPLKDFIMNGLKSANRILGKDVFCASDWTFGTVLDRVRHE
                     VQVFYAPTRDVTIHIDSHPCKITKGEKIAVISSGKWPEPYFRSMLEGIGLQVLDLWRDS
                     DQFYSFYRIGSAL"
     mRNA            join(6023..6290,6341..14137,14234..14968)
                     /gene="dtpA"
                     /locus_tag="F9C07_2283794"
                     /product="non-ribosomal peptide synthetase module"
     gene            6023..14968
                     /gene="dtpA"
                     /locus_tag="F9C07_2283794"
     CDS             join(6452..14137,14234..14413)
                     /NRPS_PKS="Domain: AMP-binding (446-844). E-value: 3.5e-82.
                     Score: 268.0. Matches aSDomain:
                     nrpspksdomains_F9C07_2283794_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (983-1048). E-value: 3.4e-17. Score:
                     54.3. Matches aSDomain: nrpspksdomains_F9C07_2283794_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1094-1362). E-value:
                     1.2e-38. Score: 124.8. Matches aSDomain:
                     nrpspksdomains_F9C07_2283794_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1532-1930). E-value:
                     1.1e-76. Score: 249.9. Matches aSDomain:
                     nrpspksdomains_F9C07_2283794_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2076-2138). E-value: 1.5e-13.
                     Score: 42.6. Matches aSDomain:
                     nrpspksdomains_F9C07_2283794_PCP.2"
                     /NRPS_PKS="Domain: Condensation_DCL (2210-2481). E-value:
                     7.7e-34. Score: 109.0. Matches aSDomain:
                     nrpspksdomains_F9C07_2283794_Condensation_DCL.2"
                     /codon_start=1
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="JGIDB:Aspfl2_3_2283794"
                     /gene="dtpA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     245.1; E-value: 1.9e-74)"
                     /gene_kind="biosynthetic"
                     /locus_tag="F9C07_2283794"
                     /note="GO_function: GO:3824 - catalytic activity;
                     GO_process: GO:8152 - metabolic process"
                     /product="non-ribosomal peptide synthetase module"
                     /protein_id="QRD90553.1"
                     /sec_met_domain="Condensation (E-value: 2.9e-43, bitscore:
                     135.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-91, bitscore:
                     294.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.1e-16, bitscore:
                     47.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MSCENEAPLTRSFCRTKRRDRFSHEEAARKCRIETHDIEDIRACT
                     QEQLVYATLLSQGDEGAIAEWSFDIPESINIDFLKKAWQDMVRSKAFLRTRIIADDSPG
                     IFLCVVMNGEPLLWTEGDGMDDPWVLGSSLARFRLIEVPNTNQRRLVVKIHHAICDPCS
                     LYAVFESVDHAYQKKKLYNLQQNETPTACTTEGSFDDATAFPELPASVQCPSARHSLEQ
                     SVSVGTLPPSLGEITANVWLAWAITQSQYQSSDRVLFGTGSRHDEERPGFPAYVSPRLV
                     VLDSQVAVADILQELENMFIGPAQKRTAVRTPSAEKKGMSGAVQTVVSVRRLAQHRPLT
                     CANLVKSEKQNPFQNYALTLDCQLEKDFLIKVQAHYDHNVIPQWVTQRVLSHFMHVLPQ
                     TFHRNRDTKLASLKSLSPYDEAQLAYWNSKHVPVAEEPTHHIIHRICMEQPNAEAICSW
                     DGKFTYNEVDVLSDSLATQLTDLGLGGSGSIIPVYMDKGRWVPIAILGVLKSGAAFTLF
                     DPSHPLQRLKIMAEDVKAKAILCSRMTMELASQIVPQTLQIDDERGWDTIRARPGSHFS
                     RSSRQDDALYVAFTSGSTGKPKAIVIEHGSYCTGAKEHIKAFRLSRKARVLQFALYAFD
                     VSIMEILSTLMAGGCICILNEVQRTTPQDFEKALSSFSVTHAFLTPSFARSLRNAQLPS
                     LDVLILGGEPMSPADAGHWASRNVVLMNAYGPAECSVNTTVQPCAAACPGNIGFTTGAA
                     CWVVDPMNHNQLVPIGGIGELLVQGPIVGRGYLNNPTLTKASFVKFVPSISAHLPGAEI
                     IDRAYRTGDLVRQQMDGSIVYIGRKDQQVKIRGQRIELSEVEFQVQKSLEGDVDVVIEA
                     VDIEGKSQPLLVAFLNLGIHGAQANEDLAPLAMPCEEWFRRLESMEGALKHYLPPSMIP
                     NLFLPLVYTPTTPTGKIDRRLLRELSSRLSQAQLELYRNRNKDELKRQPYTQVEETLQR
                     LFSQILGVEQRHISVTDSFFQLGGDSISAIRLIGAARDAGLEFTVSELLSAPTISEVAL
                     YSRALSVPKEEASPPPPFVLLGTSAKVPEILQLVANQIKLSNLDNIEDIYPCTALQEGM
                     FALSLKSPGTYTGEVLLRLPGDVDMQRLLSAWQATVEANPILRTQIVQTPKGLFQVVMR
                     RVDFECKQHASLDALGKLHVNQDKGVSINPMCQVALVKHNGDQHFALKIHHALCDGWSL
                     KLILGQLDLAYRKEASLTPSYFNTFIKYLDSIAGWEDYWTSEFRDLQAPIYPALPSPSY
                     MPRPTSLRDHAIHNLHMADSGMRLPILIKLAWSILVSNYTDSDDVVIGLTLNGRNAPVP
                     GIEQLIGPTITTVPLRTRIHEDDTVRTASNCLHNKLTAMISYEQAGLQRIGKLNDNCRT
                     ACSFQMQVGIQPPADFNTENYCFDVLEHSIGPSMDYSDFSTYGIVVVCELSRSGTALHV
                     KMRHDPDLVSPDEANCMVHLFEHLLRQLCENPDMRLNQLELAGPQDIKQFAKWNATAPV
                     PVERCLHELIMNHSRTQPGASAICGWDGYVTYQELGLLITQLAYYLRTRFHIRPGMNVP
                     ICPNRSKWAIVSMLSVLYAGGSCVLLDPNHPQARMQTVISDTAADIIICNAGTEEKVTG
                     LTRHLVIVGPELLESLPTPASLPQCLSDATPMDPAFVIFTSGSTGKPKGIIMSHKSLST
                     SIYYHSPQLGVNQQTRTLHFCSYAFDASIYEIFTTLVCGGCVCVPSASDCTDNLAGFIT
                     HFDVNLAIMAPSVARLLHPDSVPSLQCLVLGGEALTWEIVNLWADRVRLVNGYGPAEAT
                     IMAAGVVQASDWITGLIGPVVGANPWITKPFNPDQLVARGMIGELLIEGPVLADGYINA
                     PEKSADPFIPAPTWLRSIRPNSAGATRLYRTGDLVQQQRDGSIRFMGRRDNQVKLRGQR
                     IELQEVEHCVTSHVPDAVVVAEVVSFLTNERRRNELVVFIRDSTAGTEPDNITSNPEET
                     SAIFSSPTKVDHTAMAELKAHMARNLPRYMVPWIILPLDDIPKTASGKTDRARLRVAAG
                     KLEQKTLDQYMNIANIVKRQPSTTQEALVRSIFAQVLSLPESTIGVDDSFFNIGGDSIS
                     AMRFLTLCRQANLHLAMPAFLTYNTVALFCTNASTSIDISRFDASEEMDRNTPLVTIDH
                     EKHISTLRTTLCNQLGLDSVLSIEDIYPCSSSHAGIIRGLAGSGDRHQVRAIFKLHGSK
                     VVDPAHVLECWHKLIQRHAILRTVIVNNPLHPGEFLHVVLKQPPIDMASLSFQSPNVVT
                     QLCDIHPSFDWETSPAHQMVIAQGYEGEAYCKLEAGKALIDWSSFSILVDELCLAINHL
                     LPSKPAPLYKDFISYVQRQPLDKIMNYWERTLSGVTSSIIPRSLPEAPADPDAVPVLHS
                     TRITLDGFKDIDAFWRGNRLTLTNIFQVAWGLVLSFHSRLPEVCFGTVVSGRDIPVTNI
                     EDMVGPCFNILPCRLDLSPDRNIMETLQQNQQDMQRRTDHQHCSISEITRGVRQTTSTP
                     LFNTCLSVQVSLSSQMEEPSGDLGHDIQVSMVDIHDPTEYDICLAVLIYRTQIEIDLRY
                     WSFAFSEQDATRLLNNLRQAISHIVAHSARPIASIDWEA"
     CDS_motif       6647..6739
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0001"
                     /evalue="3.80E-03"
                     /label="C2_DCL_024-062"
                     /locus_tag="F9C07_2283794"
                     /protein_end="96"
                     /protein_start="65"
                     /score="9.6"
                     /tool="antismash"
                     /translation="WSFDIPESINIDFLKKAWQDMVRSKAFLRTR"
     CDS_motif       6899..6946
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0002"
                     /evalue="1.70E+00"
                     /label="NRPS-E2"
                     /locus_tag="F9C07_2283794"
                     /protein_end="165"
                     /protein_start="149"
                     /score="1.8"
                     /tool="antismash"
                     /translation="LVVKIHHAICDPCSLY"
     aSDomain        7790..8983
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F9C07_2283794_AMP-binding.1"
                     /evalue="3.50E-82"
                     /label="F9C07_2283794_AMP-binding.1"
                     /locus_tag="F9C07_2283794"
                     /protein_end="844"
                     /protein_start="446"
                     /score="268.0"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="MEQPNAEAICSWDGKFTYNEVDVLSDSLATQLTDLGLGGSGSIIP
                     VYMDKGRWVPIAILGVLKSGAAFTLFDPSHPLQRLKIMAEDVKAKAILCSRMTMELASQ
                     IVPQTLQIDDERGWDTIRARPGSHFSRSSRQDDALYVAFTSGSTGKPKAIVIEHGSYCT
                     GAKEHIKAFRLSRKARVLQFALYAFDVSIMEILSTLMAGGCICILNEVQRTTPQDFEKA
                     LSSFSVTHAFLTPSFARSLRNAQLPSLDVLILGGEPMSPADAGHWASRNVVLMNAYGPA
                     ECSVNTTVQPCAAACPGNIGFTTGAACWVVDPMNHNQLVPIGGIGELLVQGPIVGRGYL
                     NNPTLTKASFVKFVPSISAHLPGAEIIDRAYRTGDLVRQQMDGSIVYIGRKDQQVKIR"
     aSModule        7790..9595
                     /complete
                     /domains="nrpspksdomains_F9C07_2283794_AMP-binding.1"
                     /domains="nrpspksdomains_F9C07_2283794_PCP.1"
                     /locus_tags="F9C07_2283794"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7964..8005
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0003"
                     /evalue="9.90E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="F9C07_2283794"
                     /protein_end="518"
                     /protein_start="504"
                     /score="6.7"
                     /tool="antismash"
                     /translation="LGVLKSGAAFTLFD"
     CDS_motif       8207..8263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0004"
                     /evalue="4.70E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="F9C07_2283794"
                     /protein_end="604"
                     /protein_start="585"
                     /score="25.3"
                     /tool="antismash"
                     /translation="YVAFTSGSTGKPKAIVIEH"
     CDS_motif       8621..8650
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0005"
                     /evalue="1.50E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="F9C07_2283794"
                     /protein_end="733"
                     /protein_start="723"
                     /score="5.4"
                     /tool="antismash"
                     /translation="YGPAECSVNT"
     CDS_motif       8750..8839
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0006"
                     /evalue="6.70E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="F9C07_2283794"
                     /protein_end="796"
                     /protein_start="766"
                     /score="40.8"
                     /tool="antismash"
                     /translation="PIGGIGELLVQGPIVGRGYLNNPTLTKASF"
     CDS_motif       8948..9013
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0007"
                     /evalue="3.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="F9C07_2283794"
                     /protein_end="854"
                     /protein_start="832"
                     /score="35.3"
                     /tool="antismash"
                     /translation="YIGRKDQQVKIRGQRIELSEVE"
     aSDomain        9401..9595
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F9C07_2283794_PCP.1"
                     /evalue="3.40E-17"
                     /label="F9C07_2283794_PCP.1"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1048"
                     /protein_start="983"
                     /score="54.3"
                     /tool="antismash"
                     /translation="EETLQRLFSQILGVEQRHISVTDSFFQLGGDSISAIRLIGAARDA
                     GLEFTVSELLSAPTISEVAL"
     CDS_motif       9470..9499
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0008"
                     /evalue="1.40E-01"
                     /label="PCP_mE"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1016"
                     /protein_start="1006"
                     /score="5.6"
                     /tool="antismash"
                     /translation="SFFQLGGDSI"
     aSDomain        9734..10537
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F9C07_2283794_Condensation_DCL.1
                     "
                     /domain_subtype="Condensation_DCL"
                     /evalue="1.20E-38"
                     /label="F9C07_2283794_Condensation_DCL.1"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1362"
                     /protein_start="1094"
                     /score="124.8"
                     /tool="antismash"
                     /translation="EDIYPCTALQEGMFALSLKSPGTYTGEVLLRLPGDVDMQRLLSAW
                     QATVEANPILRTQIVQTPKGLFQVVMRRVDFECKQHASLDALGKLHVNQDKGVSINPMC
                     QVALVKHNGDQHFALKIHHALCDGWSLKLILGQLDLAYRKEASLTPSYFNTFIKYLDSI
                     AGWEDYWTSEFRDLQAPIYPALPSPSYMPRPTSLRDHAIHNLHMADSGMRLPILIKLAW
                     SILVSNYTDSDDVVIGLTLNGRNAPVPGIEQLIGPTITTVPLRTRI"
     aSModule        9734..12865
                     /complete
                     /domains="nrpspksdomains_F9C07_2283794_Condensation_DCL.1"
                     /domains="nrpspksdomains_F9C07_2283794_AMP-binding.2"
                     /domains="nrpspksdomains_F9C07_2283794_PCP.2"
                     /locus_tags="F9C07_2283794"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9800..9916
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0009"
                     /evalue="3.40E-08"
                     /label="C2_DCL_024-062"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1155"
                     /protein_start="1116"
                     /score="25.8"
                     /tool="antismash"
                     /translation="TYTGEVLLRLPGDVDMQRLLSAWQATVEANPILRTQIVQ"
     CDS_motif       10094..10141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0010"
                     /evalue="1.90E-05"
                     /label="C3_DCL_135-156"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1230"
                     /protein_start="1214"
                     /score="17.3"
                     /tool="antismash"
                     /translation="IHHALCDGWSLKLILG"
     CDS_motif       10433..10528
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0011"
                     /evalue="1.10E-12"
                     /label="C5_DCL_263-294"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1359"
                     /protein_start="1327"
                     /score="40.3"
                     /tool="antismash"
                     /translation="DVVIGLTLNGRNAPVPGIEQLIGPTITTVPLR"
     aSDomain        11048..12241
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F9C07_2283794_AMP-binding.2"
                     /evalue="1.10E-76"
                     /label="F9C07_2283794_AMP-binding.2"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1930"
                     /protein_start="1532"
                     /score="249.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="HSRTQPGASAICGWDGYVTYQELGLLITQLAYYLRTRFHIRPGMN
                     VPICPNRSKWAIVSMLSVLYAGGSCVLLDPNHPQARMQTVISDTAADIIICNAGTEEKV
                     TGLTRHLVIVGPELLESLPTPASLPQCLSDATPMDPAFVIFTSGSTGKPKGIIMSHKSL
                     STSIYYHSPQLGVNQQTRTLHFCSYAFDASIYEIFTTLVCGGCVCVPSASDCTDNLAGF
                     ITHFDVNLAIMAPSVARLLHPDSVPSLQCLVLGGEALTWEIVNLWADRVRLVNGYGPAE
                     ATIMAAGVVQASDWITGLIGPVVGANPWITKPFNPDQLVARGMIGELLIEGPVLADGYI
                     NAPEKSADPFIPAPTWLRSIRPNSAGATRLYRTGDLVQQQRDGSIRFMGRRDNQVKLR"
     CDS_motif       11228..11269
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0012"
                     /evalue="6.10E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1606"
                     /protein_start="1592"
                     /score="4.3"
                     /tool="antismash"
                     /translation="LSVLYAGGSCVLLD"
     CDS_motif       11468..11527
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0013"
                     /evalue="7.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1692"
                     /protein_start="1672"
                     /score="27.6"
                     /tool="antismash"
                     /translation="AFVIFTSGSTGKPKGIIMSH"
     CDS_motif       11876..11899
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0014"
                     /evalue="3.90E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1816"
                     /protein_start="1808"
                     /score="4.3"
                     /tool="antismash"
                     /translation="YGPAEATI"
     CDS_motif       12014..12097
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0015"
                     /evalue="5.20E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1882"
                     /protein_start="1854"
                     /score="31.6"
                     /tool="antismash"
                     /translation="GMIGELLIEGPVLADGYINAPEKSADPF"
     CDS_motif       12206..12271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0016"
                     /evalue="8.90E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="F9C07_2283794"
                     /protein_end="1940"
                     /protein_start="1918"
                     /score="33.8"
                     /tool="antismash"
                     /translation="FMGRRDNQVKLRGQRIELQEVE"
     aSDomain        12680..12865
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F9C07_2283794_PCP.2"
                     /evalue="1.50E-13"
                     /label="F9C07_2283794_PCP.2"
                     /locus_tag="F9C07_2283794"
                     /protein_end="2138"
                     /protein_start="2076"
                     /score="42.6"
                     /tool="antismash"
                     /translation="EALVRSIFAQVLSLPESTIGVDDSFFNIGGDSISAMRFLTLCRQA
                     NLHLAMPAFLTYNTVAL"
     CDS_motif       12749..12778
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0017"
                     /evalue="3.50E-01"
                     /label="PCP_mE"
                     /locus_tag="F9C07_2283794"
                     /protein_end="2109"
                     /protein_start="2099"
                     /score="4.5"
                     /tool="antismash"
                     /translation="SFFNIGGDSI"
     aSDomain        13082..13894
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F9C07_2283794_Condensation_DCL.2
                     "
                     /domain_subtype="Condensation_DCL"
                     /evalue="7.70E-34"
                     /label="F9C07_2283794_Condensation_DCL.2"
                     /locus_tag="F9C07_2283794"
                     /protein_end="2481"
                     /protein_start="2210"
                     /score="109.0"
                     /tool="antismash"
                     /translation="GSGDRHQVRAIFKLHGSKVVDPAHVLECWHKLIQRHAILRTVIVN
                     NPLHPGEFLHVVLKQPPIDMASLSFQSPNVVTQLCDIHPSFDWETSPAHQMVIAQGYEG
                     EAYCKLEAGKALIDWSSFSILVDELCLAINHLLPSKPAPLYKDFISYVQRQPLDKIMNY
                     WERTLSGVTSSIIPRSLPEAPADPDAVPVLHSTRITLDGFKDIDAFWRGNRLTLTNIFQ
                     VAWGLVLSFHSRLPEVCFGTVVSGRDIPVTNIEDMVGPCFNILPCRLDL"
     CDS_motif       13142..13213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0018"
                     /evalue="2.90E-06"
                     /label="C2_DCL_024-062"
                     /locus_tag="F9C07_2283794"
                     /protein_end="2254"
                     /protein_start="2230"
                     /score="19.6"
                     /tool="antismash"
                     /translation="DPAHVLECWHKLIQRHAILRTVIV"
     CDS_motif       13427..13468
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0019"
                     /evalue="9.30E+00"
                     /label="NRPS-E2"
                     /locus_tag="F9C07_2283794"
                     /protein_end="2339"
                     /protein_start="2325"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="LIDWSSFSILVDEL"
     CDS_motif       13793..13885
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0020"
                     /evalue="1.90E-13"
                     /label="C5_DCL_263-294"
                     /locus_tag="F9C07_2283794"
                     /protein_end="2478"
                     /protein_start="2447"
                     /score="42.8"
                     /tool="antismash"
                     /translation="VCFGTVVSGRDIPVTNIEDMVGPCFNILPCR"
     CDS_motif       13934..14032
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F9C07_2283794_0021"
                     /evalue="4.00E-04"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="F9C07_2283794"
                     /protein_end="2527"
                     /protein_start="2494"
                     /score="12.7"
                     /tool="antismash"
                     /translation="QQDMQRRTDHQHCSISEITRGVRQTTSTPLFNT"
ORIGIN
        1 ctacgagcat cccttgcgcc cttacagctt acaacagaag atcggtgagc ccctgtcgta
       61 accaagaatt tatgattgac tcagctctta gctactgacg accccttaca tcgtcgatga
      121 tgttggacga acgtataatt gtgagagggt gaccttaatg cagtggccaa agcaccgtgt
      181 agcttacgta gatcactcag tcattccata ctctgtaccc agaccgcttc caaaggtttc
      241 atttttgtcg tatcaggata gcatcgatac atgttacatt aaacaattcc tagttctctt
      301 cgttttgtcg gtcgttctaa tctagcgatt ccttgaccat atcgcgcctt tttgtcttcc
      361 tgacaacaat ggacacgatg ttttctgaag cactttctag agcagtcttg catgccccga
      421 cagtgggtgt aatagctact ctatcactaa tagcctcatt tctcataatt tttgtgtcgg
      481 atctcattca ttgtgggttc aaaacatggg cggtacgatg ggctccttgt atcgcaggaa
      541 agtcactgct gagtgaacgg ttccgtttga agaagtcgat ggaagactac tatgaggagt
      601 tcgctgatgc atatcgaaag gcaagtttct cagcttcaat gatgattgca cggtcacact
      661 cgcagctcta actgtactac cagtacagca aaaatggcaa agccttctcg atatcggaca
      721 atataggtga gggatatatc gtgatgcttc caccgcaaca ctaccacgat tggtacaacg
      781 ttcctaggga ccaccttaat tggggaaagg cggttaacca ggtgagtacg atgatatacc
      841 atcatagttg cactatcaca gtccccattg tcttggggtg gaatacatca aataacagtt
      901 accatctagg agttttcatt ggacgacctt gggatagatc ttggatggca tatcgctcct
      961 ctgactgtgc agaagtgcag ccaagtggac tttatcagta tgggatctga aggttttatg
     1021 ggatgtctag agaactaatt gcttgctcta gagagagtcg agggcccaat cggccgtgaa
     1081 cttgatcgct tgctggtgga aaatttgact gaatccaaag gtatgtatga ggcaaggata
     1141 tataccagca gccgaaggtt aataaaaata gaatggcacc tatgcagtct gttcaatact
     1201 gtagtgaata tctacagtca tatcgccctt ctggttgtgt taggccctga gttttccaac
     1261 catacagctc ttgctgagca actcccgtta ttcaacatgc agttgtcgga tcgaatgggc
     1321 tcagagaaat cttaccccat gtttttcaag ccccttgttc gaaaattctc agccaagact
     1381 cgtcaggtcc aatctattat ggcggagatg aaaaaaacaa ttgtgcccga aatccgacgc
     1441 cgagttgaac aaaggcgaag aagcactaaa caaagtactc aaaattgctt tctagacgtg
     1501 atgatcgagt tattattgaa gaaaggtctt ttgagtcatg atgccgtgaa agacgacgag
     1561 cgacattttg atacgatggc aatccagaca atatttcttt tatttgaggt tctcggaggc
     1621 cttacaccag caacgactag ttcactctat caaatcatga agactcctga gtatttagct
     1681 cctctgagag aagaactcgc ggctgcccta aaacaagccg ataatgcatg gagctttgac
     1741 attttcaagc acacccctaa gcttgagagc tttactaagg agtgtctccg tgtctttacg
     1801 ccttctggaa gttagtattt tccatcaacc tgctttcgta aggagaaatg ctaataacag
     1861 tcatccctgc agttgcaagt ggtgggctgg tagaaaagcc actgcaactc cgttcaacag
     1921 gtcgcactct tagtcctgga actaaatttt ccctcccagc tcagcaagct caccttgacc
     1981 cagacaacta tcctaaccca aatatctttg atggttaccg cttttgtgac cctcagtcag
     2041 gcgcttgtga tattcgaggg acaataacac catccgccaa atggttgatc tttggtatag
     2101 gaacttctgc ctgccctgca cggctactag cgaccaggat ctctcaaact ctattcttca
     2161 aggtcttaag gaagtatgac ttgaggctaa agctcgacaa tggccagccg gaggttgtat
     2221 atgctgcgac aaatatgttt gtgaacttta acactcaaat gtatgtgaag agcgcaagta
     2281 tctaaagtga attaaatata catttttcca tttacaccta gttgtataac aattcagtaa
     2341 gttgttatga gaagacataa tttcttgctg aaattgtttg ctcttctatt cctctacaag
     2401 gattcttcaa tctgggcctc aaggggcagt gatggaatat gccttgcttt actttaatgc
     2461 ttgtaataaa tcaagattat atacagtagc tcatgcattc atcatctagg agagctgctc
     2521 gcggcgatcc ccagtggaga gagtgaatgc cagcgcatag ctcccttgat aaacgcattg
     2581 gttcatggca gtccgttgta acctgcggat tcggccaggc gaccctcctc aaccgccccg
     2641 tcaagctggg cgccaactca cgctgctatt tctgggacca gaataacggc caccataatg
     2701 actcaaagcc cttgatagag agggttggag gcctcatcca gccacaaaat aaacatgaca
     2761 gctggttgga gctcaggcac tacgacttct cattcttttg gatcttcttc acctagcttc
     2821 atgccagctg tcttggtccg ctccttaaga atgagagtta gctgaatgtg cagcccatca
     2881 gcctgtgttt cttccatgat ggctgagtgg cattacaccc attctatctt agctggtctc
     2941 ggaaagcgcc ttgtggtctg gaactctgag gtgtctgcat gattcgtgta tggccaactg
     3001 gatttgggac cacaacggtc tgccgggccg cttgactggt ctagtcaaac ggatcaagac
     3061 aacaacgtgt ccagtgtaca gggcgtttca tcgagatagt catcatacct tctgtagcct
     3121 cgtattgtat gtaactacat agtaaggagt atgagttgag caattatcaa gctttacagc
     3181 tattggatga tagattaaaa tagaaatcaa ccttctcgac caccactttt acccagcaca
     3241 gttaggtccc aatttcaatg gctagaacta taaagggata gctttataac cttggaattt
     3301 ctcttgatat tgttcgggat gagaaccaaa tggcgaggta agggcaacat cggccggggc
     3361 ctagacttca ggcacaccgc tcatctcatg ccacgccgca atacggagaa taaatttcca
     3421 ttaatacctc ctacagacag acattatatg tgcatcatgt gaaatgaatc taaggcaagg
     3481 gacgccatac cgatcgtgat caaagggcgt ctggaatgcc ggttagggac ggggaaggtt
     3541 tcacatttca ttgaagaaga tttatactgc cgattggaat gtggctctgt gcggtccctg
     3601 gccacgataa tccttgatta tcatagttct ccaagaccct aaaggacagt atttcattac
     3661 atctccacaa agctccatac tatatgctat gttcagaaag gtgctcatga tcagagcaat
     3721 caaccagatt agcgaatagg gacccatgat cagaaaggtt cgtatgatgg tgatcttctt
     3781 aaaaaaaaaa aaatgaagcc tttaaagcag tattaccaaa actctatctg gatgagttgg
     3841 aagcgtagta tgatgtacaa tacaattatc ctttctagcc aatctgctga tggaaagaca
     3901 aatgccggac gagtctagac atgttggttg aaacagaatt gcagatccct tactgctgag
     3961 gtacttacag atattcgtca actgccctaa aaccaagtag ctactacaaa gagcacagat
     4021 cttcctatcc ctcctcctgt cgcaagatcg tcgactttat cattcagaac ctgaacaatg
     4081 gtgaagaaca atgccggcat cgtcaacatg ttcgagaagc ggcggactca aacgactacc
     4141 attccaatta ttgagatcat gagagagaag cggtcggagg atctggaaac ggagattgtt
     4201 caaggtcttc aatttgacag tcttcagctg cctcaggagt tgttgtggga tgatgctggg
     4261 caaatactat ttgacgattt gtgcaactcc tcgacctact accttacaaa aaaagagaag
     4321 gaaatcctac agaaatattc gaccgatatg gctgcaacaa ttcccgaggg aagtacgctc
     4381 attgagctcg gttgtgggta ggttaaacct ttaccattgc aaacttggct gacaccaagg
     4441 tttcagaagc ttgcggaaaa caggaatttt attgtccgcc ttggaaaaaa gccacaaggc
     4501 agtaacatac tacgccttgg acgtgtccca ggactctctg gagaatggcc tggcccagct
     4561 ccacaagggc ctcggatgcc ttgatcatgt cgagctgcga gggctttggg gcacatacga
     4621 agacgctata gcgtggcttg cagatcaaca ccctattaac gtccacaacg gtatcacctt
     4681 cctctggatg ggaaacagca tgaccaatat gcatcttgcc caagcgcagt cccttttgtc
     4741 tcgcatgaca aagacatgta ttgggtcggg gatcccatgc cagatcctgg tatcggtcga
     4801 tagttgctca gcagaggaca ttgtgatggg tgcttatgac acagattccc aaccgcttaa
     4861 ggattttatt atgaacggac tgaagtccgc aaaccgcatt ttagggaagg acgtgttttg
     4921 cgcttctgat tggacatttg gcacagtttt ggatcgtgtg cgacatgagg tccaggtgtt
     4981 ttacgctcct actcgcgatg ttaccatcca cattgattcg catccgtgca aaattaccaa
     5041 aggggagaag atcgcagtta taagtagcgg gaaatggcca gaaccatact tccggtccat
     5101 gttagaagga attggtctgc aggtgcttga cttgtggagg gacagtgacc agttttattg
     5161 tatgaaccct ttaccactga tctgttcctt tcccggctaa cctttcattc gattcgaagc
     5221 cttctaccgt ataggctcgg cactgtaaac cacgttgggc tccagcccca gtgatatcca
     5281 ccgccactgg agaagtagtt tagagctaag agcgtgcagc atctgttcga cagaggacaa
     5341 gtagcgaagg gcagagctgg tcaagcttaa tgctaactaa atttagctat atttcactgg
     5401 acatagagtg tatttgcgtc tcccggtggc atccatgttg tgaacataag tagctagatt
     5461 acagcaagcc attgcgagca tccggaaagg ggaaaaaaaa aaaaaaaaaa gggtggccag
     5521 cagcataagg tttacccaac ttacactggc agtgtttcag ttttccggtt actcaaatct
     5581 gtattgtacg aaaaaaattc gaagtagtag ctcataagaa aagattttct agaccagcgg
     5641 tgtcgggtac actattccac gtggccgaca aaagacccgc tgcgtggttg cttttagcct
     5701 aacacaccct caacagatat agaaatggcc tctttgaata ggcctattgg cctaatagaa
     5761 gcctgaaata ttgggaattt tggaaagttt tcagagcgtg attggggttg tgaggtaccg
     5821 cgggacggaa ggtcaggttg actcgtttat gttgagcgcc agctgaactg agtttccatg
     5881 caggacgaag tcagtattgt agcgcacaga aggtaaaagc aaggagtagt agaggtaatt
     5941 aggagctttg tagaagacag cagaggaagg aaatggaaag catgtacagc atgcgcaagg
     6001 gagcacgccg acagtaaggg aaatcaaacg gaaagaagcg gaacagtagc ggtattggaa
     6061 agcagcaaca taacttgaaa tcacaccagc atagctaaat gtgtcatcat ctcagtagaa
     6121 gttactgagc tgttatgtct tcgctcttct agacgcgcaa tttacattcc ctcctggtat
     6181 tggtattacg gtaagttact gcggatgata acaatcgcaa ctaggtgtga ctggcaaaca
     6241 cctagaccgg gtaaattatc tgcaaagggt aatataaagg gacttgaaat gttgtcacgg
     6301 tgctctgcac atagcctcca agcctaacga ttttgattag ggtgtgttac atagagtgtg
     6361 gttgtttcta cgagccacca gttgaaaagc gagcactctc cgtgcacagg gccaccaagc
     6421 taaataggcc accgggcact gagaacgcac aatgagctgc gagaatgaag cacctttgac
     6481 acgttcgttt tgtcgaacta agaggaggga caggttcagc cacgaagaag ctgccagaaa
     6541 gtgcagaatt gaaacgcatg acattgagga tatcagagca tgtacacaag agcagctagt
     6601 atatgccacg ctcttgtctc agggggacga gggggccatt gcggaatgga gttttgacat
     6661 cccagaatca atcaacattg attttctaaa gaaggcatgg caggacatgg tacggtcaaa
     6721 ggcgttctta cggactcgga tcatcgcgga tgactctccc ggaatctttc tgtgcgttgt
     6781 tatgaatgga gagccactct tatggaccga gggcgatggt atggatgatc cttgggtact
     6841 tggttcctcg ttagcgcggt ttcgtctcat cgaggtgccg aatacaaacc aacgtcggct
     6901 tgtcgtcaaa atccaccacg caatatgcga cccgtgttct ttgtatgcgg tgtttgagtc
     6961 cgttgatcat gcttaccaga aaaagaagct ctataatctc caacagaatg agactccgac
     7021 ggcgtgcacc acagaaggat cctttgacga tgcaaccgct ttccccgagc ttccggcgtc
     7081 agtgcagtgt ccttctgcta ggcattccct agagcagtca gtctcagtgg gcacattgcc
     7141 acccagcctg ggcgagatta ccgccaatgt ctggctagca tgggccatca cccaatcgca
     7201 gtaccaaagc agcgatcgtg tgctttttgg gacgggctca cgacatgacg aggaaaggcc
     7261 ggggttccct gcctatgtta gccccaggct ggtcgtactg gacagtcagg tggccgtggc
     7321 tgatatcctt caggaattgg aaaatatgtt catcggtcca gcccaaaaga ggacggctgt
     7381 acgcacccct agtgcagaga aaaagggcat gtcaggtgcc gtacagactg tggtgtcagt
     7441 tcgtcggcta gcccagcatc gtccgttgac gtgcgccaac cttgtgaagt ctgagaagca
     7501 aaatcccttc caaaactatg ccttgacgtt ggattgccag ctggaaaagg atttcttgat
     7561 caaggttcag gcgcattatg accacaatgt gatcccacag tgggtgacgc aaagagtcct
     7621 gagccacttt atgcatgttc taccccagac atttcatcgc aatcgggata caaaattggc
     7681 aagcctgaag agccttagtc catatgacga agctcagctg gcgtactgga acagcaaaca
     7741 tgtccctgtt gcggaagagc ctactcatca tatcatccac aggatatgca tggagcaacc
     7801 taatgccgag gccatctgtt catgggatgg caagttcaca tacaacgagg tagatgtctt
     7861 gtcggactct ttagctactc aactcacgga tcttggtctg ggtggctctg ggtcgataat
     7921 tccagtttac atggacaaag gtcgttgggt gcccattgca atacttggag tactgaaatc
     7981 tggagcagct tttactttgt ttgatccctc gcatccattg caacggctga agataatggc
     8041 cgaagacgtt aaggctaagg ctatactttg ctctaggatg acaatggagc tggcatccca
     8101 gattgttccg caaacgctcc aaattgatga tgagaggggt tgggacacaa tacgcgccag
     8161 accgggttca cacttttcac gatcatctcg gcaggatgat gcactatatg tcgccttcac
     8221 atccggctcc acgggaaagc ccaaggccat agttatcgag catggctcgt attgcaccgg
     8281 tgccaaggag cacatcaagg catttcgttt gagtaggaaa gcaagagtcc tacaattcgc
     8341 gctatacgct tttgatgtca gtattatgga aattctcagc acattgatgg ccggaggatg
     8401 catttgtata ctcaacgagg tacagcgtac cacaccacag gactttgaga aggcattgtc
     8461 cagtttcagc gtcacacacg cctttctaac gccatcgttt gccagatctc tgcgaaatgc
     8521 ccagctgcca tctctcgatg tactcatact gggcggagaa cctatgtcac cggcagacgc
     8581 tgggcactgg gcgtcacgga atgtcgtttt aatgaatgca tatggacctg cggagtgttc
     8641 agtaaatact actgtgcaac cctgtgccgc ggcgtgccca ggcaacatag ggtttacaac
     8701 tggcgccgca tgctgggttg ttgatccgat gaaccacaac caattggtgc ctatcggagg
     8761 catcggagaa ttgcttgtcc aaggtccgat cgttggccgg ggatacctta ataacccaac
     8821 actcactaaa gcatccttcg tcaagtttgt gccttcgata tcagcacatc tacctggtgc
     8881 cgaaattata gacagagcct atagaactgg ggacctggtc cgccagcaga tggacggttc
     8941 tatcgtctat atcgggcgca aagaccagca agtcaagatt aggggccaac ggattgagct
     9001 ctctgaagtg gaatttcaag ttcagaagag ccttgaaggg gatgttgacg tggtcataga
     9061 agcagtcgat attgaaggga agtcacagcc actcctcgta gcattcctga atctaggaat
     9121 acatggagca caagccaatg aggacctggc gcctttagct atgccttgtg aagaatggtt
     9181 caggcgcctt gagagcatgg aaggggcatt gaagcactac ttgccaccat cgatgattcc
     9241 aaatcttttt ttgcctttgg tctatacccc taccactcct actggtaaga ttgatcgacg
     9301 cctcttgcgg gagctttcta gcagactttc tcaagcacag ctggaactat atcggaatag
     9361 gaacaaggat gaattgaaaa ggcaacccta cacacaagtc gaggagacgc ttcaacggct
     9421 tttttcgcag attctaggag ttgaacagcg tcacattagt gtgacagaca gctttttcca
     9481 gctcggggga gactccatat cagctataag gctgattggt gccgcgagag atgcgggcct
     9541 cgagttcacc gtgagcgagc ttctatctgc accaactata tcagaggtag ccctttattc
     9601 aagagcactc tcggttccga aagaggaagc gtctccacca cctcccttcg ttcttttggg
     9661 aacttctgca aaggtccctg aaatattgca gctggtcgca aaccaaatca agctttccaa
     9721 tctagacaac atcgaggaca tctacccctg cacggccttg caggagggga tgtttgctct
     9781 ttcactcaag tccccaggca catataccgg agaagtactt ttgagattac caggggacgt
     9841 agatatgcag cgactgttgt ctgcgtggca ggcgacggta gaggcaaacc ctatcctgcg
     9901 aacgcagatt gtccagacac caaaagggct attccaggtc gtgatgcgac gggtggattt
     9961 cgaatgcaag caacatgcct cattagatgc gctcgggaag ctgcatgtca atcaggataa
    10021 aggggtttca atcaatccaa tgtgtcaggt tgcccttgtg aagcacaatg gagatcaaca
    10081 cttcgcccta aagatccacc atgcgctatg tgatggatgg tctttgaaat taattctggg
    10141 ccagctcgat cttgcatatc gtaaggaggc ttctcttaca ccatcatact ttaacacatt
    10201 catcaaatac ttggatagca tagccgggtg ggaggactac tggacttccg agttccgcga
    10261 tctccaggca cctatatatc cagcattacc ctcgccctcc tacatgcctc gtccaacatc
    10321 gctccgagac cacgccattc ataacctcca catggctgat tctggtatgc ggctaccaat
    10381 tttgatcaag ttggcctggt ctatacttgt atctaactac accgactctg acgacgtggt
    10441 aatcggctta acgttgaacg gacgaaatgc accagttcca ggtatcgagc aattgattgg
    10501 tccaacaata acaacagtac cactgcgtac ccgcatacat gaagacgata cagtccgtac
    10561 tgcatcaaat tgtcttcaca ataagttgac agccatgatt tcctacgaac aggccggcct
    10621 gcaaaggata ggaaagctca atgataactg cagaacagcc tgtagctttc agatgcaggt
    10681 tgggatccag ccaccggcag actttaacac ggaaaactat tgcttcgatg tcctggaaca
    10741 ttccattggg ccctctatgg attatagtga cttttccacc tatggcatag tggttgtatg
    10801 tgagctgagc cgtagtggca ctgctttaca cgtgaaaatg cgccacgatc ctgatcttgt
    10861 cagtccggac gaagcaaatt gcatggtaca tctctttgag catctcctgc gacagctatg
    10921 tgaaaaccct gatatgagac tcaatcaact tgagctggca gggccacagg acatcaagca
    10981 gtttgccaag tggaatgcca cagccccagt cccagtcgaa aggtgcctgc atgaattgat
    11041 catgaatcac tctcgcaccc agcctggtgc ctctgcaatt tgcggatggg atggttatgt
    11101 gacatatcaa gaactggggc tgcttatcac ccagctcgca tactatttac ggacacgttt
    11161 ccatatccgc ccaggtatga atgtcccaat ttgccccaat cggtcgaaat gggctattgt
    11221 gagtatgctt tcggttctgt atgcaggtgg gtcttgtgtg ctattagacc caaatcatcc
    11281 acaggcgagg atgcaaacgg ttatcagcga tactgcagcg gacatcatta tatgtaacgc
    11341 tggaaccgag gagaaagtca ctggcctgac acggcatctg gtcatagtcg ggcctgagtt
    11401 gctggagtcc ctgccgacac ctgcttcact gccacaatgt ctgtccgatg caacacccat
    11461 ggatccggca ttcgttatct tcacgtcggg aagcaccggc aagcctaaag gtataatcat
    11521 gtcccataaa tctttaagca caagcatata ctaccacagt ccgcaactgg gggtgaatca
    11581 gcagactcgc acccttcact tttgctccta tgcgttcgac gccagtatat atgagatttt
    11641 tacaactttg gtgtgtggag ggtgtgtatg cgtgccatcg gcctctgact gtaccgacaa
    11701 tttggctgga ttcataaccc acttcgacgt gaacttggca atcatggccc cttccgtggc
    11761 tcgtttgctt catccagaca gcgtgccttc cctccaatgt ttagttcttg gcggtgaagc
    11821 tctcacttgg gagattgtta atctgtgggc cgacagggtc aggctagtga atgggtatgg
    11881 accagcagag gccacaatta tggcagcggg agttgttcaa gcaagtgatt ggataactgg
    11941 cctcatcggt ccagttgttg gtgccaaccc ttggatcacg aagccgttca atccggatca
    12001 attggttgca cgtgggatga ttggtgagct cctcatcgaa ggccctgtgc tcgcggatgg
    12061 ttacatcaat gcaccagaga aaagtgcaga tccgttcatc ccggctccca cctggttgcg
    12121 atcaattagg ccgaacagtg cgggagctac aaggctttac cgcacgggcg atctagttca
    12181 acagcagcgt gatgggtcta ttcgtttcat gggccgtcga gataaccaag tgaagcttcg
    12241 tgggcaacga atcgagctgc aggaggtcga gcattgtgtc acttctcatg ttccagatgc
    12301 agtggtagtg gcggaggtgg tctcattcct gacaaacgaa cggcggagaa atgaacttgt
    12361 agtatttatc agagatagca ctgcaggaac agaacccgac aatatcactt cgaaccctga
    12421 ggagacctca gcaatattct cctctccaac caaggttgat cacactgcaa tggcggagtt
    12481 gaaggctcac atggctcgca atctgccacg atatatggtt ccgtggatta ttttacctct
    12541 agatgatatc cccaaaaccg cctctgggaa aactgaccga gcgcgtttgc gagtggcagc
    12601 tgggaagctg gagcaaaaga cgctggatca gtacatgaat atagcaaata ttgtaaagcg
    12661 tcagccatcg accacccagg aggcccttgt gcgtagcatt ttcgcacaag ttctctcact
    12721 accagaaagc actattgggg tagacgatag ctttttcaat ataggaggag attccatctc
    12781 tgcaatgcgg tttctcacac tatgtcgtca agcaaacctt catctcgcca tgcccgcgtt
    12841 tctcacttac aataccgttg cgttattctg taccaatgcg agtacctcga tcgatatctc
    12901 cagattcgat gcgtctgagg aaatggatcg caatactcca ctagtcacca tcgatcacga
    12961 gaaacatatc agcaccctca gaaccactct ttgcaaccag cttggcctag actcggtttt
    13021 gtcgatagaa gatatttatc cgtgttccag ctctcacgca ggtatcatca gggggttggc
    13081 tggaagtggc gatcgccatc aggtccgagc catcttcaag ctacacggca gcaaagtggt
    13141 agatccagcc catgtgctgg aatgttggca taaattgatc cagcgccatg ccatcctccg
    13201 aacagtcatc gtgaataatc ccttacatcc cggagaattc ctccatgtag ttttaaagca
    13261 acctccaatt gacatggctt ccctgtcttt tcagtcgcca aatgttgtta cacagctttg
    13321 tgacattcat ccatctttcg attgggagac ctctccagcg caccagatgg taatcgccca
    13381 agggtatgag ggtgaggctt attgcaagtt ggaggctgga aaagcgctca tcgactggtc
    13441 gtctttttcc atattagttg atgaactttg ccttgctatc aatcatctcc taccatccaa
    13501 acccgctcct ttatacaagg acttcatctc ctacgtgcag agacaacccc ttgataagat
    13561 catgaattac tgggagcgga ccctaagtgg ggtcacatca agcatcatcc cgagatctct
    13621 ccctgaggca cccgctgacc cagacgccgt acccgttcta cattccacca ggatcacact
    13681 ggatggcttc aaggacatag atgcattctg gagggggaac agactaactt tgaccaatat
    13741 ctttcaggtg gcctggggct tggtactttc ctttcacagt aggttgccag aagtctgttt
    13801 cggaacggtg gtatcggggc gtgatattcc tgtcacaaat atcgaggaca tggtcggccc
    13861 ctgctttaat atccttccct gtcgtttaga tctctctcca gaccgtaata tcatggagac
    13921 tcttcagcag aatcaacaag atatgcaacg ccgaacagat caccagcatt gctctatcag
    13981 tgaaatcacc cgtggtgtga gacaaactac ctcgacgccc ttattcaaca cttgcttgtc
    14041 ggtacaagtg agtctctcgt cacaaatgga agagccaagc ggagacttgg gtcacgatat
    14101 acaagtcagc atggttgaca ttcacgaccc taccgaggta tgttcttttt ttcgcagata
    14161 ttcctttcct tgtccctctt tatgatcaac gaagacaagg gattgttcgc tctgacgttt
    14221 ttctacttgc cagtatgata tatgccttgc agttctcatc tatcgcaccc agattgaaat
    14281 cgatttgcgg tactggagct tcgcattctc ggaacaagat gcgacgaggt tattaaacaa
    14341 ccttcgccag gcgatttctc atattgttgc tcattctgcg cgcccaatcg cgtctatcga
    14401 ctgggaggct taggctattt caaggcgaaa atgtgttaaa tcagagagct tgaagaacag
    14461 aacatatcga tcttcttttt atcttaaacg atcttgttac cgctgttacg tcaggcagcc
    14521 attcccgccg ccctaaatcg attcagaacc tcaagtgatt tgttctgtct caatcacaat
    14581 gcatccttcc ttagaatcct gaacaactcc gattccctag tactgttaca acttgtagct
    14641 cgctgacctc caacactccg aagacacatc accagttaga ttatgtatac agtggtacgg
    14701 gttcaccgct gcaccccgcc ctaaccctgt gatttccggg gacgggttga aaatgcagaa
    14761 ccgctcagat aatcttggtt tccctatcgt atattgaaaa gagaagaaga gagagatatg
    14821 gatagatatc tagagatttg ggtcgaatac tttaatatat taggtaccta gaaatgccat
    14881 tgacattaca tatatccatg ggatcttgta taaacctgta gaaaattaac gttactcctg
    14941 atctaggcac ccctgtatag tcttatctgg taatctatgt atgtaataaa ggctgttact
    15001 tctttcatac cgatcgttac tgctatgcag ccatccatta gttaccatag aaagaacccc
    15061 ggtttatttt atttgctagt tctcagtcct cgggaaagtc aggagcattt tacgctcgta
    15121 tacctgggca cgctcgttcc tgtatagtac tcaaaggagt gtggtaatta gacagagaat
    15181 cagaatccgc atacctcttc ataatacctt gaccttgggg tagaagtaac gagggaataa
    15241 tgcaca
//
