LOCUS       BGC0002158             13535 bp    DNA     linear   CON 14-MAR-2015
DEFINITION  Magnaporthe oryzae 70-15 chromosome 3, whole genome shotgun
            sequence.
ACCESSION   BGC0002158
VERSION     BGC0002158
KEYWORDS    .
SOURCE      Pyricularia oryzae 70-15
  ORGANISM  Pyricularia oryzae 70-15
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Sordariomycetidae; Magnaporthales; Pyriculariaceae;
            Pyricularia.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:03:45
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 5799813
            Orig. end    :: 5813348
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..13535
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="NRPS, PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..13535
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            163..2743
                     /locus_tag="MGG_07800"
     mRNA            join(163..1326,1419..2743)
                     /locus_tag="MGG_07800"
                     /product="hypothetical protein"
     CDS             join(178..1326,1419..2585)
                     /codon_start=1
                     /locus_tag="MGG_07800"
                     /product="hypothetical protein"
                     /protein_id="EHA53210.1"
                     /transl_table=11
                     /translation="MRQNSDYPSLGPFFFAGKIKLSIATESFSAMKRSRAESASGPQQP
                     SRRQPQTSCDLCRSRKIKCDRGTPCGNCRTRGLACSIMSPSSAPSPGASSAESAGHGRL
                     DTAILARLAALEQAVFRSTSAVGGSGNAENGAHGDATPRVPLSGLEREGRQTANFLDKA
                     YDRCSSASTRSGYRPLDIRVAESCRDSFATGAPDPVWLMPQKDAVAMVHDFVENIYHLM
                     PIVHIGSTVSVIDNVYPALQAGNINHVDPAQVALILGICAACAFFWDGGVPCQHRFETE
                     GEATSASLIWKTSALYAFEEAQRRGSRSLEGAQACAILAYLTYNMDGPSTRFYRLHTCS
                     VTACRELGIHLVDSRGCESTDSTARRELKRRLWWHVAATDWMLGLNGGPLDGTYTVHPR
                     QARVALPRNLNDSDLAIDSEILTMPPHVPTQASCFLQVIRLAEICRMVVDSQSPDDSIA
                     DTAYNERVLASDELFKKAIESMPPPLVLTSPIPEGAPRFLCLQRASLHLGFHSRRARLL
                     RPFLLYKDSDGRQGTTYRRSRELCVRSAQTVLEISTSLLEHSLRIRSPEPFRRQILHHP
                     GHHSCPASPIHRLGVVVNHLFCACAILAFECSLRKNSSVHPRQQHRGAGGEDDLDGMLV
                     HAYRLLAAAGEECTVAADLVCAMRGVFAKYRVDGDLATVDGRGGQNQIVGSSRSAMASV
                     QTSAGGACNEQQQIGPAAWPGMRGAIPDENQPMGEGSLETGKAWDGFDKDLDDLFVAND
                     TYCSWDQIFARLGSYCGP"
     gene            <3002..>3236
                     /locus_tag="MGG_16932"
     mRNA            join(<3002..3034,3114..>3236)
                     /locus_tag="MGG_16932"
                     /product="hypothetical protein"
     CDS             join(3002..3034,3114..3236)
                     /codon_start=1
                     /locus_tag="MGG_16932"
                     /product="hypothetical protein"
                     /protein_id="EHA53211.1"
                     /transl_table=11
                     /translation="MSDILIADCIKGKPGNAKELCAQYSGGTLNSLGLQKRAAFIIAVK
                     IASNLT"
     gene            complement(3762..5677)
                     /locus_tag="MGG_07802"
     mRNA            complement(join(3762..4197,4287..5393,5458..5677))
                     /locus_tag="MGG_07802"
                     /product="hypothetical protein"
     CDS             complement(join(4044..4197,4287..5393,5458..5480))
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137:Major
                     facilitator superfamily MFS 1 (Score: 307.8; E-value:
                     1.5e-93)"
                     /gene_kind="transport"
                     /locus_tag="MGG_07802"
                     /product="hypothetical protein"
                     /protein_id="EHA53212.1"
                     /transl_table=11
                     /translation="MADTAKTTARGWLALAGAAVALFCTVGFLNAFGVFQEYYSTFLDR
                     SPSDISWIGSLSIFLLYSISPFGGLLVDRVGPTLPLCAGSAGLVLALFMTSLCTQYWQL
                     MLAQSLLLGASASLVFCPPLGVVLRHMPHRRGLAMGLTIGGSSIGGIVWPIMLQRLLNN
                     NVLGFGWTMRAVAFTMMPLLAFACLAVREPPRKPASAPPAASAAVEADGRVPVSDNSDA
                     AEPVPEKEVPSRTAFLRQLTYILLCSGLALAYLGLFTPLFYVSKYAIAQGQSTSTAFYL
                     LSAVNASSFLGRVLPGYIADKFGHFNLLVLSTLLSGVVGFTWTQASSLPGLIMWALAYG
                     FTSGAVMSLQNACASKMAPPQAQGLAVGVLMGVLSISALIGTPISGQILTRSGYVALSA
                     WTGATLVAGGGVIGVARLLKYPKLMTAF"
     gene            <7153..>13328
                     /locus_tag="MGG_07803"
     mRNA            join(<7153..7217,7389..7498,7774..7945,8035..8273,
                     8326..8724,8803..12884,13098..13111,13223..>13328)
                     /locus_tag="MGG_07803"
                     /product="D-alanine-poly(phosphoribitol) ligase subunit 1"
     CDS             join(7153..7217,7389..7498,7774..7945,8035..8273,
                     8326..8724,8803..12884,13098..13111,13223..13328)
                     /NRPS_PKS="Domain: Condensation_Starter (152-445). E-value:
                     3.6e-22. Score: 70.9. Matches aSDomain:
                     nrpspksdomains_MGG_07803_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (608-1002). E-value:
                     6.9e-93. Score: 303.3. Matches aSDomain:
                     nrpspksdomains_MGG_07803_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (1148-1214). E-value:
                     6.2e-10. Score: 31.4. Matches aSDomain:
                     nrpspksdomains_MGG_07803_PP-binding.1"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (1265-1684).
                     E-value: 3.7e-98. Score: 321.0. Matches aSDomain:
                     nrpspksdomains_MGG_07803_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     127.9; E-value: 1e-38)"
                     /gene_kind="biosynthetic"
                     /locus_tag="MGG_07803"
                     /product="D-alanine-poly(phosphoribitol) ligase subunit 1"
                     /protein_id="EHA53213.1"
                     /sec_met_domain="Condensation (E-value: 1.7e-26, bitscore:
                     81.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6e-97, bitscore:
                     312.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.4e-11, bitscore:
                     31.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 2.6e-99, bitscore: 321.0,
                     seeds: 2284, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYNRCCRKVWIQGRVAYRPAYIRQSPPQQTLYRGIDLLPFTTIVM
                     DHQSGFQNPSPSGGLMFSASAKRFISRIVGFVGRGAEVQQKAVGLCPLKTERRRAAAGG
                     LLLPTGLRMGRSIIMSVRPLPFLTGPAPSPDTAAGFKPSPPTGNLVSVSPLSKAQMALW
                     FDYLQHPTSTHYFLTLKVELDKQPLSLDKIIQVIRGLGKQHAMLRTTFHVDTDTDDMSK
                     SYMAVHDDSWDQEIHVLMNDAQLYEALRKPFQLSSESPVRWVVQMKLQPGSARSTYTVY
                     AAGHHIGVDGASMSVLSNQLLEAVASEVEDQPDHSGPHYGDYIQRQARYLRSSAGAAAG
                     RFWLSQLRHTQPFRWRMEPPEEINTPNYRQLDTWNFFPTAEIQEWGNLYKTSWFRVATS
                     IVGLVTAAMAEPQAHHDHALMVAFGARPRGFENNVSHMANTMPVKFPLSSLLRDDATFS
                     DAVKAMGRNVSTAKKHENFPFMSLMEQANRHMDPTLLDFKVAITYSPKLANKSCELFPV
                     EGIWDLFFCFLEQEDGVALGVISNPRVFGAEALGQLQSLFNEVFALSKARPSFKLSDLA
                     FLQNRTPARFISGPALDDVESISKSRVYRLIKARAASQPDLVALMSAEKGVQMTYRELA
                     AQSSQVAHFLQKQRLCKGDAVLVHLERGFAQIVWILGVMEAGACYVALDKTWPAARKEA
                     ILRTANGKLLVTDDEQMDFEKQDTTVVFLAPSAAEIASMPQSTCECEVADDDLAYVVFT
                     SGSTGQPKGVMVEHSNLSHYVSATRSLVKTGPHSRMLQLASFAFDAIVLEYAVTLAHGG
                     TLCFANHPEVLVGEYLADVIDSNQVNFFHCTPSVLSTLPAGRRLPSLRIVSVGGEASPP
                     GLLDHWRKRVELLHAYGPTECTVICTLESLTQDESTQTAIDATVIGKALPNLDIRICEE
                     GKLEPLAPNQVGEICVVGPQVSRGYMGQEELTASKFHNITLADGHPSRLYRTGDKGFID
                     DDGKLHIQGRIGNREIKVRGYRLDLYEVEKNVMAFDPEVTQVSIQQVGESLVALVVPAS
                     IDCDRIRSKLLKDMPRYAVPTRFIRVASLPLNTNGKIDHTQASSLAAELVMHDTVLPTV
                     DATPTPTAAVRAVGVTEENLRLKTKENGMERQEMLRRHLTAEVTALWAKLLGSSRQFDP
                     EVGFFDAGGHSLLLTQLHKLIKERFGTGSRPSLLDIFSMSSIRKQVDCLMGIVDQDAML
                     GSEPTGGSSSRSQSRRSAETSSSSTSAPSSVPVDAERNLYAIVGISCRFPGANTAEQLW
                     NVLMEQRDAITTFCPAENLGFALEENSVFVPRYGMIDALKDFEPSAYSMSDAEAQTIDP
                     QKRVFLDVAADALADAGTSASPGNPLDPVGVFVGAATNTFLSSRDNPGSKPPGDEEPQS
                     FANHYQQLLDCPIGTFASFKLNLTGPVVTLNTACSSALAALHLACASLSHGDCNAAVVG
                     GVSMAYPQEGGYVTARPGGDSSAVFSPSGVCHPLDSRADGCVPADGAAALVIKRLADAR
                     ADGCRVYAVIEGVAVSADGSDDKAGLGVPSSSGQSRTVEAALRRAGPQALSRLRYVEMH
                     GSGTPWGDALEVQGLKMAFDRLSKTGAAEQSGTGRAQPEADRIYLGSNKGNCGNTEAAS
                     GLLSLIKASMALNLGVVPPLPNLAEPNPKCEFEETKFEPLGKQLALAPGDRVMNKRQRI
                     VRSPNWISDATWFVISTVDNLLPKLTPAAVA"
     aSDomain        join(8144..8273,8326..8724,8803..9152)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MGG_07803_Condensation_Starter.1
                     "
                     /domain_subtypes="Condensation_Starter"
                     /evalue="3.60E-22"
                     /label="MGG_07803_Condensation_Starter.1"
                     /locus_tag="MGG_07803"
                     /protein_end="445"
                     /protein_start="152"
                     /score="70.9"
                     /tool="antismash"
                     /translation="SPLSKAQMALWFDYLQHPTSTHYFLTLKVELDKQPLSLDKIIQVI
                     RGLGKQHAMLRTTFHVDTDTDDMSKSYMAVHDDSWDQEIHVLMNDAQLYEALRKPFQLS
                     SESPVRWVVQMKLQPGSARSTYTVYAAGHHIGVDGASMSVLSNQLLEAVASEVEDQPDH
                     SGPHYGDYIQRQARYLRSSAGAAAGRFWLSQLRHTQPFRWRMEPPEEINTPNYRQLDTW
                     NFFPTAEIQEWGNLYKTSWFRVATSIVGLVTAAMAEPQAHHDHALMVAFGARPRGFENN
                     VSHMANTMPVKF"
     aSModule        8144..11459
                     /complete
                     /domains="nrpspksdomains_MGG_07803_Condensation_Starter.1"
                     /domains="nrpspksdomains_MGG_07803_AMP-binding.1"
                     /domains="nrpspksdomains_MGG_07803_PP-binding.1"
                     /locus_tags="MGG_07803"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       8592..8648
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MGG_07803_0001"
                     /evalue="1.20E-03"
                     /label="C3_starter_134-155"
                     /locus_tag="MGG_07803"
                     /protein_end="303"
                     /protein_start="284"
                     /score="11.9"
                     /tool="antismash"
                     /translation="HHIGVDGASMSVLSNQLLE"
     aSDomain        9642..10823
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MGG_07803_AMP-binding.1"
                     /evalue="6.90E-93"
                     /label="MGG_07803_AMP-binding.1"
                     /locus_tag="MGG_07803"
                     /protein_end="1002"
                     /protein_start="608"
                     /score="303.3"
                     /tool="antismash"
                     /translation="ARAASQPDLVALMSAEKGVQMTYRELAAQSSQVAHFLQKQRLCKG
                     DAVLVHLERGFAQIVWILGVMEAGACYVALDKTWPAARKEAILRTANGKLLVTDDEQMD
                     FEKQDTTVVFLAPSAAEIASMPQSTCECEVADDDLAYVVFTSGSTGQPKGVMVEHSNLS
                     HYVSATRSLVKTGPHSRMLQLASFAFDAIVLEYAVTLAHGGTLCFANHPEVLVGEYLAD
                     VIDSNQVNFFHCTPSVLSTLPAGRRLPSLRIVSVGGEASPPGLLDHWRKRVELLHAYGP
                     TECTVICTLESLTQDESTQTAIDATVIGKALPNLDIRICEEGKLEPLAPNQVGEICVVG
                     PQVSRGYMGQEELTASKFHNITLADGHPSRLYRTGDKGFIDDDGKLHIQGRIGN"
     CDS_motif       10059..10118
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MGG_07803_0002"
                     /evalue="7.50E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="MGG_07803"
                     /protein_end="767"
                     /protein_start="747"
                     /score="33.8"
                     /tool="antismash"
                     /translation="AYVVFTSGSTGQPKGVMVEH"
     CDS_motif       10632..10715
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MGG_07803_0003"
                     /evalue="9.10E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="MGG_07803"
                     /protein_end="966"
                     /protein_start="938"
                     /score="34.0"
                     /tool="antismash"
                     /translation="NQVGEICVVGPQVSRGYMGQEELTASKF"
     CDS_motif       10824..10871
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MGG_07803_0004"
                     /evalue="3.40E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="MGG_07803"
                     /protein_end="1018"
                     /protein_start="1002"
                     /score="10.3"
                     /tool="antismash"
                     /translation="REIKVRGYRLDLYEVE"
     aSDomain        11262..11459
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MGG_07803_PP-binding.1"
                     /evalue="6.20E-10"
                     /label="MGG_07803_PP-binding.1"
                     /locus_tag="MGG_07803"
                     /protein_end="1214"
                     /protein_start="1148"
                     /score="31.4"
                     /tool="antismash"
                     /translation="EVTALWAKLLGSSRQFDPEVGFFDAGGHSLLLTQLHKLIKERFGT
                     GSRPSLLDIFSMSSIRKQVDC"
     aSDomain        11613..12869
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MGG_07803_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="3.70E-98"
                     /label="MGG_07803_PKS_KS.1"
                     /locus_tag="MGG_07803"
                     /protein_end="1684"
                     /protein_start="1265"
                     /score="321.0"
                     /tool="antismash"
                     /translation="AIVGISCRFPGANTAEQLWNVLMEQRDAITTFCPAENLGFALEEN
                     SVFVPRYGMIDALKDFEPSAYSMSDAEAQTIDPQKRVFLDVAADALADAGTSASPGNPL
                     DPVGVFVGAATNTFLSSRDNPGSKPPGDEEPQSFANHYQQLLDCPIGTFASFKLNLTGP
                     VVTLNTACSSALAALHLACASLSHGDCNAAVVGGVSMAYPQEGGYVTARPGGDSSAVFS
                     PSGVCHPLDSRADGCVPADGAAALVIKRLADARADGCRVYAVIEGVAVSADGSDDKAGL
                     GVPSSSGQSRTVEAALRRAGPQALSRLRYVEMHGSGTPWGDALEVQGLKMAFDRLSKTG
                     AAEQSGTGRAQPEADRIYLGSNKGNCGNTEAASGLLSLIKASMALNLGVVPPLPNLAEP
                     NPKCEFEETKFEPLGKQLAL"
     CDS_motif       12096..12143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MGG_07803_0005"
                     /evalue="2.80E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="MGG_07803"
                     /protein_end="1442"
                     /protein_start="1426"
                     /score="13.4"
                     /tool="antismash"
                     /translation="GPVVTLNTACSSALAA"
ORIGIN
        1 ccacgggctt aattgtggat ctctcggtat cagggatgag ccctgagcta gagcgattga
       61 agttaggcga aggagtggac ccgcttttgg ccgtgcgtcc ctcccttttg taccttgtca
      121 gttttaatat aatcaaggtt gcttttctct cattcggacc cgagctcttg aaccagcatg
      181 aggcaaaatt cggattatcc gtcgctgggg cctttttttt ttgcgggaaa aataaaacta
      241 tccatcgcaa cggagtcatt ttcggcaatg aaacgtagca gggccgagag cgcctcgggg
      301 ccgcagcaac cctcccgacg gcagccacag acctcgtgtg atttatgccg ctccagaaag
      361 atcaagtgcg acaggggaac cccctgcggg aactgccgca cccgcggcct ggcctgcagt
      421 atcatgtcgc cttcgtccgc cccttctccg ggcgcctcgt cggccgaaag cgcgggacac
      481 ggcaggctgg ataccgccat cttggcacgc ctcgcagcgc tcgagcaggc cgtcttccgg
      541 agcacttccg cggtgggggg cagcggcaat gccgaaaacg gggcccacgg tgacgccacg
      601 ccccgggtgc cgctgtccgg gctggagagg gaagggcgcc agacggccaa ctttctcgac
      661 aaggcgtatg acaggtgctc cagcgccagc accaggtccg gctaccggcc gttggatata
      721 cgcgtggccg agagctgccg ggattccttc gccaccgggg ctcccgatcc ggtgtggttg
      781 atgccacaaa aagacgccgt agccatggtg catgactttg tcgaaaacat ctaccacctg
      841 atgcccatcg tgcacatcgg ctcgaccgta tccgtcatcg ataacgtcta tcccgcgcta
      901 caggccggga atatcaacca cgtcgacccg gcccaggtcg ccctcatcct cggcatctgc
      961 gccgcctgcg cctttttctg ggacggaggg gtgccctgcc aacaccggtt cgagacggag
     1021 ggggaagcca ccagcgcgtc gctcatttgg aagacgtctg ccttgtacgc gtttgaagag
     1081 gcccagaggc gaggctcgcg atcgctcgag ggcgcccagg cctgcgccat ccttgcctat
     1141 ctgacgtaca acatggacgg tccctcgact cggttttacc gtctgcacac gtgctcggtc
     1201 acggcctgcc gcgaactggg gatccacctg gtcgacagcc gcggctgcga atcgaccgac
     1261 agcaccgcca ggcgagagct gaagaggagg ctctggtggc acgtcgcagc gacagactgg
     1321 atgctggtaa atacagccga tgtgtttttt tttttgttcc ttttcttaaa aaaagaaaaa
     1381 ccgattttgg ttctttatta acttttcgta aaatttaggg cctcaacggc ggaccccttg
     1441 atggcaccta cacagtccat ccgcgacagg ccagggtcgc gttacctcgc aacctcaatg
     1501 acagcgatct tgccatcgac tcggagatcc tgacgatgcc gccccacgtc ccaacgcagg
     1561 caagctgctt cctgcaagtg atccgccttg ccgaaatctg tcgcatggtt gtagattccc
     1621 agagccccga cgacagcatt gccgacacgg cctacaacga acgtgtcctc gcgtccgacg
     1681 agctcttcaa aaaggccatc gagagcatgc cgcctccgct cgtgctgacc tcgccgatcc
     1741 ccgagggcgc cccgcggttc ctgtgcctgc agcgcgcttc cctccacttg ggctttcact
     1801 cgcgcagggc tcgcctgctg cggccgttcc tgctctacaa ggactcggat ggccgccaag
     1861 gcaccacgta ccgacggtcc agagagctct gcgtgcgctc cgcccagacg gtgctggaaa
     1921 tctccacctc gctgctcgag cattcgctgc ggatacgatc cccggagccc ttccgccggc
     1981 agatcctcca ccaccccggt caccacagct gcccggcttc gcccatacat cgcctgggcg
     2041 tcgtggtcaa ccacctgttt tgcgcctgcg ccatcctggc attcgagtgc agcttgcgca
     2101 agaactcgag cgtgcaccca aggcagcagc atcgcggagc gggaggagag gacgatctgg
     2161 acggcatgct ggtccacgca taccgcctgc tggcggccgc gggcgaggag tgcaccgtcg
     2221 ccgccgacct ggtgtgcgcg atgaggggtg ttttcgcaaa gtaccgcgtg gatggtgact
     2281 tggcgaccgt ggatggccga gggggccaga atcagattgt cggcagcagc aggtcagcaa
     2341 tggccagtgt ccagacgtct gcggggggtg catgcaacga gcaacaacaa atcggacccg
     2401 ccgcatggcc cgggatgcgt ggtgccatac cggatgaaaa ccaaccgatg ggtgagggca
     2461 gtttggagac gggcaaggcg tgggatggct tcgacaagga cttggacgac ttgttcgtcg
     2521 ccaacgatac gtattgcagc tgggatcaga tatttgcccg gctagggtca tactgtggcc
     2581 cttgacacaa acgtcaacta tctttagcgt tgcgtacccc ctgatggcca cccctaaaaa
     2641 tccaacaacg aatgccgtta attgtaattt ctctctttct ctaatttaga atttcgttga
     2701 tgacgtttaa tgtattagaa ttctccaata tatgcctggc cgcgacatgg acaacgtttt
     2761 cttaaaaata aaaaaccaca gtttttggaa aaccaataaa gcgtttagca aacgacgaaa
     2821 ggttaaaaaa acacgtatct gtgaaggagg gttatgcacc gtacataagg tttaaattct
     2881 gctgcaatta acaaaggaga aaatggggag ggaaacaatg cgcaactggc gattaaccgg
     2941 cgctgtggca attgtggcaa tatgcgatat aatgcacgca cctgttgaca agatgcaaaa
     3001 aatgtctgat atacttattg ccgactgcat caaggtaaaa tcaacaatgc aaacgttgca
     3061 attggagata gaaatggtgt agtacacacc aacccctgaa tgaatatgga cagggtaagc
     3121 ctggaaatgc caaggagctt tgtgcgcagt actcgggcgg tactttgaac tctttgggat
     3181 tgcagaaacg agccgcgttt ataatagccg tcaaaatcgc ctctaatctg acataaagag
     3241 ttggcgtgag ggattttggt gttttatatt gtaaaaaatg tagccgaaat tagtacgaaa
     3301 attagcatta gatttgaaat accgcttttg tatcttttct tttcgttgtt tttcgatata
     3361 ttaatctacc ttgtttttgc acctaaaacc ccatgcgctc tgtgtaccgg ataaccccat
     3421 aacagactaa tgaaagacat tttattggct ttatttaact agggataccc ctagtccata
     3481 ttcattcagg ggttggtgtg taggaaaagc ggccagggta cttataaacc acgattgttt
     3541 atttttatat tactgactac cgttcatgca tttgatttat aaatcagtgg agacggggtg
     3601 gggcgcgtgc cacttcacct gaggtgagtt atatgaacca acactttttg gaataactga
     3661 cgtgatttac caaaaagagg atttaaaata aaagcacgat ttttaattgc aaatataatt
     3721 ttcaagcatg taaaaaaggg actgcaagca tacgagacct aggctctaca gatcggttaa
     3781 ttaattacaa gtcctatcag caaaaaggtt aaatcatagt aaaataaagt ttgggttctt
     3841 ggccttgtca agcagctttt tgacccatgt tagtgcagct accgcagttt tcgagcctga
     3901 ttattgcaag tttacccagc cacagtatcg aagagccacc tcggctcgca tctttctcca
     3961 gttagtcctg gctattatta atacatattt ccacacccct tcgatccccg ttggaagagg
     4021 caattgggcc cacctcgact cgattagaaa gcagtcatga gcttgggata cttcaacaac
     4081 ctcgcgacac caatcactcc acctcccgcg accagggtag caccggtcca ggcggacaaa
     4141 gccacgtacc ccgagcgggt gaggatctgt ccgctgatgg gcgtgccgat aagcgcacta
     4201 ttttgtagtt tggggggtgt tagtcggctc ctgtcccgat acggtcttca ggggccggga
     4261 acaaaaaaaa aaaaagaaaa acttacgaga tggagaggac acccatcagc acgccgacgg
     4321 cgaggccctg cgcctgtggg ggtgccatct tgctggcgca cgcgttctgc aggctcatga
     4381 cggcgcccga ggtgaagccg taggccaagg cccacatgat cagccccggc aagctgctgg
     4441 cctgagtcca ggtgaagccg acgacgcccg acaagagggt ggagaggacc agcaggttga
     4501 agtggccaaa cttgtcggct atgtagcccg gcagcacccg ccccaaaaag gaggaggcgt
     4561 tgacggccga caagaggtaa aaggccgtcg acgtcgactg gccctgggcg atggcgtact
     4621 ttgacacgta gaagagcggg gtgaagagtc ccaggtaggc caaggcgagc cccgagcaga
     4681 ggaggatgta ggtcagctgc ctgaggaacg ccgtcctgct cgggacctcc ttctcgggga
     4741 cgggctctgc cgcgtccgag ttgtcggaaa cagggactcg gccgtcggcc tcgacggccg
     4801 cgctggctgc ggggggcgcc gacgcaggct tcctgggcgg ctccctgacg gcgaggcagg
     4861 cgaacgccag caggggcatc atggtgaagg cgacggcgcg catggtccag ccgaagccca
     4921 ggacgttgtt gttgagcagg cgctgcagca tgatgggcca cacgatgccg ccgatggagg
     4981 agccgccgat ggtcaggccc atggccaggc cgcggcggtg cggcatgtgg cgcagcacca
     5041 cgcccagcgg cgggcaaaag accagcgacg cgctggcgcc caggagcagc gactgcgcca
     5101 gcatcagctg ccagtactgc gtgcacagcg aggtcatgaa cagggccagc accagacccg
     5161 cgctgcccgc gcacaggggc agcgtgggcc cgacccgatc gacgagcagg ccgccaaagg
     5221 gcgagatgga gtagagcaaa aagatggaca gcgaccctat ccatgatatg tcggaaggac
     5281 tgcggtcgag aaacgtagag tagtattcct ggaagacgcc aaacgcattg agaaagccca
     5341 cggtgcagaa gagcgccacc gccgcgccgg ccagcgccag ccagccgcga gcactgggtt
     5401 gcatgtcagc aaaggtgcac gagattaaaa gagagcgaaa aaaggtgctt gactaacgtg
     5461 gtcttggctg tgtcggccat tttgatggtg tcgtgtggta ccacccagtc gagtaggtgt
     5521 actgtacaaa cactcttaaa tggtgatgtg atataccagc ttgcacgctt ggtgtaagcg
     5581 gcgtttcttt tccgccagag ttggctgagt tggaacacca cagattggct gtgaagaata
     5641 agtgctatgc ggtatcatgc tagtactgaa cacagctagg cgccagggtg ggatgaaaag
     5701 agagcaagac aacatttgtg agcgactgac attgaatccc tttttcctct agccataccg
     5761 cggataatcc gggtccacgt taccattttc ggattatccg cggcttggac tccccacccc
     5821 agccgccacg taccatagta gatttgaacc agggtatttt tgtgtcgatc cacagtttca
     5881 tcgcaaaacc ataattgaac tacggttcaa ttgtggagct cgcggctcag ggatcaagcg
     5941 ctgagattaa cgccatcctt tgcttgtgga gcgaccggaa aagggatgag ccctgagatt
     6001 aacgctcggt tgcattctgc aagggggttt gtttagtctg agaattgaaa ccaatgtgga
     6061 aagcgattcg caaaatacca tcccaagcaa agcacgaaat agtaattgtg gtaggtttct
     6121 gccgtcttac aactcggaga aaacatccga gctgataagc aaacctaccc tggtagctgc
     6181 ctttctattc gtaccccctt gtcaggtccc tcgttctagc acttgccaca aaactatact
     6241 attttcggta gtaaataaaa attatttagc aaaggtactt ctggctttcg gttatagata
     6301 accttttatc ccaaaccgcc aaacgactcg ctcgtgcacg tatgcatatg tattggacct
     6361 tgagttaatg agcttccgtt ctttggttta acgaaacgtg ggtgtacttg gagcgtatat
     6421 aaaacgtata tatgagaaaa aaatgaaaaa caagctcagt tattttgggg aaagactttg
     6481 gggcgaaacc gacagtaata tatatggtag tcgaatagct actatttttt ggagatgttt
     6541 gcataatgca aaattgcaat aaaaccgtta atattcataa tagaatgacg ttccaggtta
     6601 taaatgcagc agtattcaaa gaatatatgc atatattggg tattataaaa ctaatacggc
     6661 cgcctttttc tccggaccta aatcccattg caaatgcgtc ggactggata aaggattata
     6721 cccaaaacta tcatggactt taaaatgcat ttatctaaaa ttacggaggc gaattcagga
     6781 gatttgggaa atattgccgc ttgaatggtt gcaggaatga ctggctgcta tgcagcaaag
     6841 gccgtcgact gtactttaga ctgacgggat gcaagttccg ttgtaggggt tgtttggtgt
     6901 tattgttgtt gtaaatagtc tcaagttcat aagcgattct atatttctat caagtaccgt
     6961 tgtttttctt tatcctgaaa tcgctgccga atctggttta gatgtaaact ttaatacccg
     7021 ccatgaacac gtcaaggggc actatcctta cccctaccac cgaaagcagt tcaccatcga
     7081 tccacacggt acaaacctta gtgctggcaa gactcgggcc gtggggcctt tcgccatcgt
     7141 ggtgatgtcg caatgtacaa tcgatgctgc aggaaggtgt ggattcaggg tcgagtggcg
     7201 tatcggccgg catatatgta agtagaccct ggaagttact acggtagcag gcgcaaaaaa
     7261 acaaaaaaaa gccacccctt gtcgccgtgt actatgtatg catgcgtggg cctttatcaa
     7321 cttgactgtc cgcgggaacc atcaagtacc taaattgttt ttttttttgt taaaaaatat
     7381 taccaaagtc ggcaaagccc accccagcag acattgtaca ggggcattga tcttttaccc
     7441 tttaccacca tagtaatgga ccaccagagt gggttccaaa acccttctcc ttcgggaggt
     7501 gagctccggt gactgcacaa gttatcaaat cgtccctcac cgagccttgc cagatgcggg
     7561 tttcgaggaa cgcccattct ccgcttcgcc caaacgtgat gaaagaggcg cattggtccg
     7621 ggcgcccatg ggcatcaaac tacaatacct tttttttccc cgcagcttga acctgtatgg
     7681 gcgggtccgt gattcaaaaa aagagaggca taaacttttg gcaatggatc accgtggcat
     7741 cctaacgggg caggccctga ctagagcgtc taggcctcat gttttccgcc agcgccaagc
     7801 gctttatctc ccgcatcgtg ggattcgtgg gccgcggcgc cgaggtgcag cagaaagccg
     7861 tgggactttg tcctttgaag acagaaagac gtcgggcagc ggcagggggg ctgctgctgc
     7921 cgacgggcct taggatgggg agaaggtata aagactatgg agaggcttga cgttatccac
     7981 gggggtttgc catttttttc cattattcat ctataccatt accctgtgta ccagtatcat
     8041 catgtctgtc aggccactac cttttctcac ggggccagcc ccaagccctg atacggcggc
     8101 tggcttcaag cccagcccac ccacaggcaa cctcgtttct gtttccccgc tatccaaggc
     8161 gcagatggcc ctgtggttcg actacctgca acacccaacc tctacacact acttcttgac
     8221 cctcaaggtt gagctggaca agcagcctct cagcctggac aagataatac aaggtatggc
     8281 acactcgtct tgcccagaaa atctgcgcat gctgaccggc tacagtcatc cggggcttgg
     8341 gcaagcaaca tgccatgctg cgcacaacct tccacgtgga cacagataca gatgacatgt
     8401 caaagtcgta catggccgtc cacgatgatt cgtgggacca ggagatccac gtcctgatga
     8461 acgacgctca gctctacgaa gcgctgcgga agccgttcca gctgtcctcg gaatcccccg
     8521 tccgctgggt tgtccagatg aagctccagc ccggcagcgc tcggagcacc tacaccgtct
     8581 acgcggcggg gcatcacatc ggcgtggacg gggcgtccat gagcgtgctg tcgaaccagc
     8641 tcctggaggc cgtggcgtcc gaggttgagg accagcccga ccacagcggc ccccactacg
     8701 gggactatat ccaaagacag gcaagtttca tgtggggcct tttttccaga caccttcctt
     8761 gttaagttgt ttgctagtat gctgactttg ttttccagga aggatatctg cgcagttcag
     8821 caggtgcggc ggctggcagg ttctggctct cgcaactgcg acacacccag ccgttccggt
     8881 ggcggatgga gccgccagaa gagatcaaca ccccaaacta ccgtcagctg gacacgtgga
     8941 actttttccc gaccgctgaa atccaggaat ggggcaacct atacaagacg tcctggtttc
     9001 gcgtggccac gtccatagtg gggctcgtca ctgcggccat ggctgagccc caagcccacc
     9061 acgaccatgc tctgatggtg gcgtttggag ccaggcccag gggctttgaa aacaacgttt
     9121 cgcacatggc caacaccatg cccgtcaagt ttcccctgtc gtcgctgctg cgggacgacg
     9181 ccaccttttc ggacgcggtc aaagccatgg gccgcaacgt ttccacggcc aaaaagcacg
     9241 aaaactttcc attcatgtcg ctcatggagc aggcaaatcg gcacatggac cccacgctgc
     9301 tggacttcaa agtggccata acatactcgc ccaaacttgc caacaagagc tgcgagctgt
     9361 ttcccgtgga gggcatatgg gacctgttct tttgcttcct cgagcaggag gacggcgtgg
     9421 ccctgggagt catcagcaac ccgcgtgttt tcggcgcgga agctctcggc cagctgcaaa
     9481 gcttgttcaa cgaggttttt gcgctgtcaa aggcccgccc gagctttaag ctgtccgact
     9541 tggcgtttct gcaaaacagg acgcccgctc ggttcatctc gggcccggcc ctggacgacg
     9601 tcgagagcat cagcaagtcg agggtttacc ggctgatcaa ggccagagcg gcgagccagc
     9661 ccgacctcgt cgctctcatg tcggcagaaa aaggtgtgca aatgacgtac cgcgaactcg
     9721 cagctcagag cagccaagta gcccactttc tccaaaaaca gcgtctttgc aagggcgatg
     9781 cagtcctcgt ccacctggaa cgcggcttcg cccagatcgt atggatcctc ggcgtcatgg
     9841 aggcgggtgc ctgctatgta gcactcgaca agacctggcc cgcagccagg aaggaagcca
     9901 tcctgaggac ggccaacgga aagctgttgg tcacggacga cgagcaaatg gactttgaga
     9961 agcaagacac gaccgtcgtg ttccttgccc cgtccgcggc cgagatagcc agcatgcccc
    10021 agagcacgtg cgaatgcgag gttgcggatg acgatctggc ctatgtcgtc ttcacatcgg
    10081 ggtccacagg ccagcccaag ggcgtcatgg tcgagcactc caacctgagc cactacgtca
    10141 gcgcgacgcg cagccttgtc aagaccggac cccattcccg catgctgcag ctcgcgtcct
    10201 ttgcctttga cgccatagtg ctcgagtacg ccgtcaccct cgcccacggc ggtaccttgt
    10261 gctttgccaa ccacccagag gtgctggtgg gcgagtacct ggccgacgtt atcgacagca
    10321 accaggtcaa cttcttccac tgcacacctt cggtcttgtc gacccttccg gcagggaggc
    10381 ggctgccctc gctgcgaatc gtctccgtgg gaggcgaggc ctcgccacct ggcctgctcg
    10441 accactggag gaagagggtg gaactgctgc acgcgtacgg cccgaccgaa tgcactgtca
    10501 tctgcacact ggaaagcctg acccaagacg aatcgaccca gaccgccatc gacgccaccg
    10561 tcatcggcaa ggcgctgccc aacttggaca ttcgcatatg cgaggaaggc aagctggagc
    10621 ctcttgcacc caaccaagtc ggcgagattt gcgtcgtcgg accgcaggtc tcccgcgggt
    10681 acatgggcca ggaagagctc acggccagca agttccacaa catcactctt gccgacggcc
    10741 acccgagccg gctatatcgc actggcgaca agggtttcat tgacgacgac ggcaagctgc
    10801 acattcaggg ccggatcgga aaccgcgaga tcaaggtccg gggataccga ctggacctgt
    10861 acgaggtgga gaagaacgtc atggctttcg accccgaagt cacccaagtg tcgatccagc
    10921 aagttggaga gtccctggtg gcactcgtgg tgccggcctc gatcgactgt gaccgcatcc
    10981 gcagcaaact gctcaaggac atgccccgtt atgcagtgcc cactcgcttc atccgagtcg
    11041 cgagcctgcc gctgaacacg aacggaaaaa tcgatcacac ccaggccagc agtcttgcgg
    11101 cagagctggt gatgcatgat acggtcttgc ccacggtcga tgccactcct acccctactg
    11161 ctgctgtacg agctgtcggc gtgacggaag agaatctgcg tctcaagaca aaagaaaatg
    11221 gcatggaaag acaggagatg cttcgcaggc acctcacagc cgaggtcaca gccttgtggg
    11281 ccaaacttct gggttcttct cggcagttcg accccgaagt cggattcttc gatgctggcg
    11341 gccacagcct cttgttgacc cagctccaca agctgatcaa ggagcgtttc ggcacggggt
    11401 cgcgacccag cctcctggac atctttagca tgagctcgat ccggaaacag gtcgactgcc
    11461 tcatggggat tgtggaccag gatgccatgc tcggatccga gcccactggt ggcagcagct
    11521 ctcggtcgca atccagacgg tcggcagaaa ccagctcttc ttccaccagc gctccaagca
    11581 gcgttcctgt cgacgccgaa aggaacctgt acgccatcgt gggcatctcg tgccggttcc
    11641 ccggcgccaa taccgccgag cagctgtgga acgtgctcat ggagcagcgc gatgccatca
    11701 ccactttttg ccccgccgaa aacctcggct tcgccctcga ggagaacagc gtgttcgtgc
    11761 cgcgctacgg catgatcgac gcgctcaagg acttcgagcc gtcggcgtac tccatgtccg
    11821 acgccgaggc ccagaccatc gacccccaga agcgcgtctt cctggacgtg gccgccgacg
    11881 ccctggccga cgcgggcacc tcggccagcc ccggaaaccc gctggacccc gtgggcgtgt
    11941 tcgtcggcgc ggcgaccaac accttcctct cctcgcggga caacccgggg agcaagccgc
    12001 ccggcgacga ggagccgcag tcctttgcca accactacca gcagctgctc gactgcccca
    12061 tcggcacctt tgcctcgttc aagctcaacc tgaccgggcc ggtggtgacg ctcaacacgg
    12121 cgtgctcctc ggcgctcgcc gcgctgcacc tggcctgcgc ctcgctctcg cacggcgact
    12181 gcaacgccgc cgtggtgggc ggcgtgtcca tggcctaccc gcaggagggc ggctacgtga
    12241 ccgcccggcc gggcggcgac tcgtcggccg tcttttcccc ctcgggcgtc tgccacccgc
    12301 tcgactcgcg cgccgacggc tgcgtgccgg ccgacggcgc ggccgcgctg gtgatcaagc
    12361 ggctggccga cgcccgcgcc gatggctgcc gggtgtacgc ggtgatcgag ggcgtggcag
    12421 tcagtgccga cgggtccgac gacaaggccg ggctgggcgt gcccagctcc tcgggccaga
    12481 gccgcaccgt cgaggcggcg ctacgcaggg cggggcccca ggcgctcagc cgcctgcgct
    12541 acgtcgagat gcacggctcc ggcaccccct ggggcgacgc gctcgaggtg caagggctca
    12601 agatggcatt cgaccgcctc agcaagaccg gtgccgcaga gcagtccggc acgggccggg
    12661 cccagccgga agcggacagg atctacctgg gctccaacaa gggcaactgc ggcaacaccg
    12721 aggccgcctc gggactgctg agcctgatca aggcgtccat ggccctcaac ctgggcgtcg
    12781 tgcctccgct gccgaacctg gccgagccca accccaagtg cgagttcgaa gagaccaagt
    12841 tcgagccgct cgggaagcag ctggccctcg cgccggggga ccgagtaggt gtcaccagtc
    12901 tgggttatgg cggcagcaat gcgcacgtgg tcttggcctc ggcgcagctt ttcggggtgg
    12961 aacagaaggc tttcttttga gcagggcgga ctcggagcaa tattttattc tagtcttttt
    13021 tttattctgt agattccgtg ttgagataat tcattgttta aacttggttt agcagcactg
    13081 atatggtatt accgtaggtg atgaacaaaa ggtgaatcaa aagttcaaaa catgattttt
    13141 aaaaaaatct acgtccgcga gtgggcggtg ccccgcgcga tttaacgtac aaattggaca
    13201 tgtttcgctt tgtcgctaac agacaaagga ttgttaggtc gccaaactgg ataagcgacg
    13261 ctacttggtt tgtaattagc actgttgaca acttattgcc caagctcaca cctgcagctg
    13321 tggcgtagat ggagttcctg ccatacttga aaatagcagg gttctaatgg gcagatgcac
    13381 cttcccgtct tgtcgagtgg cgacttggct accaccataa atgcaagact tggtggccca
    13441 caacttcctc gccttgttgt tccgttaagg ggggaccttt gatgtgcagg cgactgagtg
    13501 acagggaact ccagagttgt tgttcccctc acgac
//
