BGC0002158 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002158 (Pyricularia oryzae 70-15)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	13,535	tenuazonic acid	NRPS:Type I+PKS	100%

BGC0002158 - Region 1 - NRPS

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Location: 1 - 13,535 nt. (total: 13,535 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 13,536
Label		BGC0002158

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002158	1.00	NRP, Polyketide	tenuazonic acid	Pyricularia oryzae 70-15
BGC0001699	0.22	NRP	nidulanin A	Aspergillus nidulans FGSC A4
BGC0001249	0.20	NRP	dimethylcoprogen	Alternaria alternata
BGC0001166	0.20	NRP	HC-toxin	Alternaria jesenskae
BGC0001641	0.20	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132	0.20	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000307	0.20	NRP	AbT1	Aureobasidium pullulans
BGC0000357	0.20	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255
BGC0001758	0.20	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001128	0.20	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002158	1.00	NRP, Polyketide	tenuazonic acid	Pyricularia oryzae 70-15
BGC0001699	0.55	NRP	nidulanin A	Aspergillus nidulans FGSC A4
BGC0001249	0.53	NRP	dimethylcoprogen	Alternaria alternata
BGC0001166	0.53	NRP	HC-toxin	Alternaria jesenskae
BGC0001641	0.53	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132	0.53	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000307	0.52	NRP	AbT1	Aureobasidium pullulans
BGC0000357	0.52	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255
BGC0001758	0.52	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001128	0.52	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 13535:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

MGG_07803

Search NORINE for peptide: strict or relaxed

AMP-binding (608..1002): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALHSGAVIK
Nearest Stachelhaus code(s):: Ile DALHSGAVIK (100% 8Å match)
Stachelhaus code match:: 100% (strong)