BGC0002168 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002168 (Aspergillus stellatus (Emericella variecolor))

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	34,234	decumbenone a/calbistrin A/calbistrin C/decumbenone B/decumbenone c/dioic acid moiety	PKS	100%

BGC0002168 - Region 1 - T1PKS

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Location: 1 - 34,234 nt. (total: 34,234 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 34,235
Label		BGC0002168

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002168	1.00	Polyketide	decumbenone a, calbistrin A, calbistrin C, decumbenone B, decumbenone c, dioic acid moiety	Aspergillus stellatus
BGC0002170	1.00	Polyketide	4-methyl-5-dimethyltetradecahexaene-β-ketolactone, 4-methyl-5-methylheptatriene-β-ketolactone	Aspergillus stellatus
BGC0002736	0.32	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0000687	0.31	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0000631	0.31	Terpene	botcinin H, botcinin I, botcinin J, cinbotolide D, botcinin K	Botrytis cinerea B05.10
BGC0000677	0.31	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001317	0.31	Terpene	lupeol	Lotus japonicus
BGC0000685	0.29	Terpene	brassicicene C	Alternaria brassicicola ATCC 96836
BGC0000688	0.28	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0001219	0.28	Polyketide	shanorellin	Chaetomium globosum CBS 148.51

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002168	1.00	Polyketide	decumbenone a, calbistrin A, calbistrin C, decumbenone B, decumbenone c, dioic acid moiety	Aspergillus stellatus
BGC0002170	1.00	Polyketide	4-methyl-5-dimethyltetradecahexaene-β-ketolactone, 4-methyl-5-methylheptatriene-β-ketolactone	Aspergillus stellatus
BGC0002736	0.66	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0000687	0.65	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0000631	0.65	Terpene	botcinin H, botcinin I, botcinin J, cinbotolide D, botcinin K	Botrytis cinerea B05.10
BGC0000677	0.65	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001317	0.64	Terpene	lupeol	Lotus japonicus
BGC0000685	0.62	Terpene	brassicicene C	Alternaria brassicicola ATCC 96836
BGC0000688	0.62	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0001219	0.62	Polyketide	shanorellin	Chaetomium globosum CBS 148.51

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 34234:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

calA_

PKS_AT (550..866): pk

ATSignature: Methylmalonyl-CoA, Malonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 54.2%; Malonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 56.1
Methylmalonyl-CoA: 50.7
Ethylmalonyl-CoA: 30.3
Malonyl-CoA: 28.7
trans-1,2-CPDA: 19.0
Propionyl-CoA: 18.9
Isobutyryl-CoA: 18.8
fatty_acid: 14.7
inactive: 14.2
3-Methylbutyryl-CoA: 12.3
Benzoyl-CoA: 11.9
CHC-CoA: 0.0
Acetyl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0