LOCUS       BGC0002170             36500 bp    DNA     linear   PLN 11-JAN-2020
DEFINITION  Aspergillus stellatus IFM 42010 DNA, reduced polyketide biosynthetic
            gene cluster, complete sequence.
ACCESSION   BGC0002170
VERSION     BGC0002170
KEYWORDS    .
SOURCE      Aspergillus stellatus (Emericella variecolor)
  ORGANISM  Aspergillus stellatus
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:05:00
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 36500
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..36500
                     /culture_collection="IFM:42010"
                     /db_xref="taxon:1549217"
                     /mol_type="genomic DNA"
                     /organism="Aspergillus stellatus"
                     /strain="IFM 42010"
     subregion       1..36500
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002170"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..36500
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             430..1995
                     /codon_start=1
                     /note="orf1"
                     /product="putative C6 zinc finger domain protein"
                     /protein_id="BBM05071.1"
                     /transl_table=11
                     /translation="MALKRNSPRHVKSGCRTCKIRRVKCDEQRPSCHKCVDSGRTCDGY
                     GIWSSPPTRVPAQQLVYPPRTLPGLGLSEKKYIDRYRNLLTQKLAEPFGSYFWNSVVLQ
                     LSLSEAAVLHATIALTSAHELLMQGRSFNEPFLLRQYNRAIQALTYKTTSLRVTIVSCV
                     VFLCIEIIRGNPIAMQAHFDAGIKLLRQLQDGKCNSTVLVRHNPEGFDDHLVDVFAKLN
                     LQFLMLGHASQQKEAFVPSFQYGGRIHSPRTFFSVLDVRQSINPILLSVIYLMKERERE
                     TLSTDKHPPRPSAALLDKQSTLQAAMSEWIESYEASITSLSAKISRSERFGLVLLRVYA
                     DVATILLATCFSIRETSYDPHVSRFEAIIKRYSDFHESVYRSEANSCPAHPFFTTDTCL
                     FPPLYFTALKCRNSTIRHRAISLLNEYDHLEGPWTGPMVAAVANHVVSLEENHFEKAMQ
                     SSGGQCDSGPIVVLPEFCRIHCVECKLDGHTKTGELTLRRFRHELGGGGGWSISKSTVL
                     FKIK"
     misc_feature    430..36246
                     /note="reduced polyketide biosynthetic gene cluster"
     protocluster    1754..36500
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[21753:30620]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      21754..30620
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1754..36500
                     /SMILES="C([*])C(-O)(C)"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             join(2221..2275,2322..2831,2882..3228)
                     /NRPS_PKS="Domain: PKS_KR (15-182). E-value: 2e-11. Score:
                     36.0. Matches aSDomain: nrpspksdomains_BBM05072.1_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     152.5; E-value: 2.4e-46)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf2"
                     /product="putative oxidoreductase"
                     /protein_id="BBM05072.1"
                     /transl_table=11
                     /translation="MNPVNTKPYQLPADATWFVTGCSSGIGRAIAEHVAAQPGHRLIAT
                     ARDPASLSYLQDSASILKLGLDVTKPESVDAAFKAAAAHFGDSYYLDVVVNNAGYSLSG
                     DTESVTEGEMHEAFETNFFGLVRVSLKAIEVMRQSKEKRGGLIFNISSLAGICAFPGHA
                     FYHASKFAVEGWSESVAREVHPDWNINFCIVEPSAVKTNFETTSKKRTAPHEAYAGADM
                     PARQLEMFVKKGLAAGVGFEPSAVAKVLYQVASRNEKVPLRLPLSATAVKLITAKLQGQ
                     LQDLETTAELSAIDVGQAQFKV"
     CDS_motif       join(2266..2275,2322..2407)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BBM05072.1_0001"
                     /evalue="4.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="BBM05072.1"
                     /protein_end="47"
                     /protein_start="15"
                     /score="19.5"
                     /tool="antismash"
                     /translation="TWFVTGCSSGIGRAIAEHVAAQPGHRLIATAR"
     aSDomain        join(2266..2275,2322..2812)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BBM05072.1_PKS_KR.1"
                     /evalue="2.00E-11"
                     /label="BBM05072.1_PKS_KR.1"
                     /locus_tag="BBM05072.1"
                     /protein_end="182"
                     /protein_start="15"
                     /score="36.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TWFVTGCSSGIGRAIAEHVAAQPGHRLIATARDPASLSYLQDSAS
                     ILKLGLDVTKPESVDAAFKAAAAHFGDSYYLDVVVNNAGYSLSGDTESVTEGEMHEAFE
                     TNFFGLVRVSLKAIEVMRQSKEKRGGLIFNISSLAGICAFPGHAFYHASKFAVEGWSES
                     VARE"
     CDS             complement(join(3580..3800,3852..5044,5100..5275))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 91.5; E-value: 9.5e-28)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf3"
                     /product="putative cytochrome P450 monooxygenase"
                     /protein_id="BBM05073.1"
                     /sec_met_domain="p450 (E-value: 8.2e-31, bitscore: 97.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAELGPLVWGVAACIALAIFIPKWIGKGAKEPPSLGGWMIANTY
                     QYMTDMHGFLQRVASAQRKSKIVKFRLGPKKIYMVSGEQNIQAINKPSHSISPDVFFLE
                     VMANVWGARKDEVSKFANDKSGRSKNPVPGHDVKPGQPRLWHGQHHVYSEYLQRADHAN
                     ALSDKYYELFSDRLKKQPLGEWQEIRLSEFFESEMAEAALVALMGPRIVKLNPGFWPAM
                     WEFARLAPRLMWGLPRWVNPKPWEIREQFHGMCRRYLDSAEKEFDWNGPDIDSEWEPHY
                     GSRMARELIGWAKNNLSPETTAGMVATFIFGTNANSVPLSTWAMMELIADPELYKAVHE
                     ECIAASTVDPATGERVFNPQKLLGMPLLQSVYIETLRLHVSINVTREVTQPITLDGHLL
                     TPGSLIQAPSQIGQYNEAVWASEGHPASQFWAGRNLKHENGKAEFTMAGRTTSFFPFGG
                     GPSICPGRVFAKQEILMTIAALVTRFEIELIDWVHPDGTKSDRPAQNDQSYIGAVGIPP
                     DRDMKVRWKRLW"
     CDS             join(5598..6151,6198..6732)
                     /NRPS_PKS="Domain: PKS_ER (33-217). E-value: 2e-14. Score:
                     45.2. Matches aSDomain: nrpspksdomains_BBM05074.1_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 142.6; E-value: 2.6e-43)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf4"
                     /product="putative oxidoreductase"
                     /protein_id="BBM05074.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.1e-12, bitscore:
                     35.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPPTQTAIVQIAKGDSSEIPLVVSKSAPIPQVQSENHVLVKVLA
                     VALNPNDHKMVTHFNTAGSIAGCDFCGVVASSNAPLGLTEGTRVCGALFPYSPADPDNG
                     SFAQYCVVDARLLVKVPDTWSDLEAASLGVGWSTISLAFSDPNALGLEGLPTKPTHQNK
                     EPVLVYGGGTASGTLACQLLKLMNYTPIAIASNRSAELATEYGAAGTASYTSKDCVDTV
                     KSIAGKPIRKVLDCITDAESAAMCYSAMARTGGNYACLEECPEAWRSRRIVKVKEVMGF
                     QVLGVDINLGDSTYTRLGDQKLFTIGTQWAREFETLMATGQLKAHPLRELPGGFDAIIE
                     GLNMLRKGEVRGQKLVVKIPQN"
     aSDomain        join(5697..6151,6198..6294)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BBM05074.1_PKS_ER.1"
                     /evalue="2.00E-14"
                     /label="BBM05074.1_PKS_ER.1"
                     /locus_tag="BBM05074.1"
                     /protein_end="217"
                     /protein_start="33"
                     /score="45.2"
                     /tool="antismash"
                     /translation="QSENHVLVKVLAVALNPNDHKMVTHFNTAGSIAGCDFCGVVASSN
                     APLGLTEGTRVCGALFPYSPADPDNGSFAQYCVVDARLLVKVPDTWSDLEAASLGVGWS
                     TISLAFSDPNALGLEGLPTKPTHQNKEPVLVYGGGTASGTLACQLLKLMNYTPIAIASN
                     RSAELATEYGAAGTASYTSKD"
     CDS             complement(join(6750..7861,7905..7995))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 159.5; E-value: 1.9e-48)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf5"
                     /product="putative acyltransferase"
                     /protein_id="BBM05075.1"
                     /transl_table=11
                     /translation="MADFDALLADYTKKENPKVHGAIFKCVDKQGNEIYSKVAGWDSVE
                     PNAAPLTEDVVLKVASATKLITSIALLQCVDKGLIGLDEPLGKHVPELADKQILIDVKD
                     LEFVHEPSKVPITARHLLTHTSGFGYRFTHRLLRMRAEAKTAAGEKPSLRITERYEMPL
                     VFEPGTGWLYGCSLDWAGVTVSRLNGGITLEQYFEENIWKKLGLSAPFPCFNIATHPEY
                     NARAMGGAMRTPDGRLQPNNTWAFDNPEDQDGGSGLSCTAKDYVAVLADLISDSPKLLS
                     PGIIAEMFVPQLQPKSVPVEQMLGLRPAWDTVSGPIAEDAINHGLGGIVTTGDVAEIRQ
                     PKGILGWGGASNIVWWVNRDLRVAGFFATQQAPFGNPTVTALVNAWKKDFWTQFKNKEN
                     A"
     CDS             8448..9476
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     138.6; E-value: 4.2e-42)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf6"
                     /product="putative oxidoreductase"
                     /protein_id="BBM05076.1"
                     /transl_table=11
                     /translation="MSLDRYAAFHAETPQGRGDGRPTAEQILRDQEPLGDWSDKVILIT
                     GGTAGLGAESTRVLHKTGAKIFIMGRDAVKGQKLADNISAVNPQFPPIEVITMDQSSLQ
                     SVRDGAAEFLKKSGRKLNVFMANAGIVASPVKETKDGFEAVFAINYLSTFLLTQLLAPA
                     LEASTTPEFKSRLVVVSSAGHRAGNVDPEKYNFMGEGYDPSKAYARSKSAAILMANEFE
                     RKYGSRGVHALSLNPGIIMDTEISRDMPGTKESRRPMYYKMEPLLASWEKDVEQGAATQ
                     VWASIAKELEGKGGLYLDDVQVAKEAKFEGQMCLPGWKPWIWDEEMAARLWKDSLEMVG
                     LA"
     CDS             complement(join(9552..9740,9789..9911,9964..10752))
                     /NRPS_PKS="Domain: cMT (168-350). E-value: 1.2e-78. Score:
                     256.0. Matches aSDomain: nrpspksdomains_BBM05077.1_cMT.1"
                     /codon_start=1
                     /note="orf7"
                     /product="putative methyltransferase"
                     /protein_id="BBM05077.1"
                     /transl_table=11
                     /translation="MASIDLSNWQTVDLQWTPDSTPTPVSQLLHPTRESQSEQEMIARM
                     WVLCAIQMQEKLKSATCTKPHFEKYRNWLASEYERFKQPGYPQVPDSGDLVALSDGERL
                     KAMNEMRERVKDTYLWPVIEGPWRVYDNVVDIVEGRVKLVKVLLKDGLLEKFYDWANSL
                     SEVRPLINLMGRTNPGLRILEIGAGTGGTTARVFEGLNPDAGKQLYSSYVFTDISPLFF
                     DSAKRRFEAYDNVEYRALDISKDPVEQGFEAGAYDVVIASNVLHATPCLVETLKNVRTL
                     LQPKGFLFNQELSPPGKYVDFMVGLLPGWWLGEADGRAGGPCIPPAEWDRRLKQAGFEG
                     LHAVGLDSEPPFYYNANMLARVAASD"
     aSDomain        complement(join(9603..9740,9789..9911,9964..10248))
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BBM05077.1_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="1.20E-78"
                     /label="BBM05077.1_cMT.1"
                     /locus_tag="BBM05077.1"
                     /protein_end="350"
                     /protein_start="168"
                     /score="256.0"
                     /tool="antismash"
                     /translation="LINLMGRTNPGLRILEIGAGTGGTTARVFEGLNPDAGKQLYSSYV
                     FTDISPLFFDSAKRRFEAYDNVEYRALDISKDPVEQGFEAGAYDVVIASNVLHATPCLV
                     ETLKNVRTLLQPKGFLFNQELSPPGKYVDFMVGLLPGWWLGEADGRAGGPCIPPAEWDR
                     RLKQAGFEGLHAVGLDSEP"
     CDS             complement(join(11202..13460,13511..14203,14253..14288,
                     14335..14450,14496..14610))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 294.6; E-value: 2.4e-89)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf8"
                     /product="putative bifunctional cytochrome P450/NADPH-P450
                     reductase"
                     /protein_id="BBM05078.1"
                     /sec_met_domain="p450 (E-value: 7.7e-82, bitscore: 265.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLSNIPQPPGVPFLGNLFDIDMELPLQSLYDLGAKHGEIYRMK
                     FPGHTFIIACSYDMVNEFCDEKRFPKTIFALKEMRHAMHDGLFTAIDGETEPAWAIAHR
                     ILVPAFGPSSLRMMYDGMYDIASQLALKWARYGGEAITVTDDFTRLTLDTIALCSMDFR
                     FNSYYKEGVHPFVEAMGDFLTESGDRARRLPIPSFFYRGKDKKFFGDIEVMRRTANEIL
                     QERKKEKNLDTRKDLLSAMLNGVDPKTGKKMTEESILDNLITFLIAGHETTSGMLSFAL
                     YHLMKDPDCYRKAQQEVDSVCGKTPIRFDQLNKLGYISAVLRETLRLTPPLPVFNVAPK
                     KDEIVGGQYVIKEGELVIVLIGASQMDPKVFGADVGVFKPERMLDENFNKLNKEFPNAW
                     KPFGNGTRGCIGRPFAWQEALLVLAMLLQNFDFEFDDPSYTLTLKQTLTVKPANFKVKA
                     IPRDGLRAFEMQNRLAGMSVSTKTTSGAAANGTAAPVSGGTGKPMKIFYGSNSGTCQSM
                     AERLAADAFSHGFSATTVDCVDNATAQLPKDEPVVIITASYEGQPPDNAAKFVPWLEGL
                     KEDSKELKDVNYAVFGCGHHDWSATFHRIPKLVDYTIDKHGGNRVAALGLTDVAQGNEM
                     TDFEAWEDNILWPALMEKYGAEAPQGPSLSVEVSTPRKSTLRQDVKEAAVVSTSVLTSE
                     DALIKKKHIEIELPSDMTYKAGDYLAVLPVNPPDQVHRVMRHFHLPRDAHLTISSKAVT
                     SLPSDGPMPAVDIFGSYVELAQAATKRDIQTLIDAAKDEKTKTKLAALATDEEYASTII
                     ASRLSVLDLLESNPDIKLPISAFLRMLPPMRVRQYSIGSSPVWSKNRVILTYTVLDEPR
                     IGTDGKRHVGVATNYMSTLQAGDVVHVAVRPSHAAFHLPADAGRTSMVMIAAGTGVAPF
                     RGFIQERAGMKGAGRKIAPATLYFGCRQPGQDDLYRSDLDNWESSGVVNVRRTFSRQVE
                     ASEGHKYVQDRLWQERKEIMSLWDQGAMIYICGGRAMGESAKEMMIEILYDAKKEKGEE
                     TSKEEVAKWFEGLKNTRYAVDIFD"
     CDS             join(15014..15285,15331..15531,15577..16837)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 297.5;
                     E-value: 4.4e-90)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf9"
                     /product="putative FAD-binding domain-containing protein"
                     /protein_id="BBM05079.1"
                     /transl_table=11
                     /translation="MLAKLFLLSLSLLSPALGLVPRQAPSSSCKAFPGDAAWPSAGAWN
                     ALNRTVGGRLIATVPLPSVCHQTPFGTFNEDACAAMKTEWLEDTTFINHPAEVMNPPTQ
                     NYSCVPFTSSSQACNMGNYASYSINVTGADDVIAGIKFARENNVRLVIKNTGHDFSGKS
                     TGPGALSLWTHNLNTTKIIENYEGAGYSGPAAKLGAGVISGQVYEVVGAAGYRVMGGTC
                     PTVGLAGGYTSGGGHSLLNGAYGMAADAVLEWEVITADGKHLTASQSENSDLYWALSGG
                     GAGTYAVVLSMTTKVFADGPIGSGILMFNITANATEDYWGAIEDLWMFLPEFVDAGPNS
                     WDFALTAAGFQAYAITVPDKNGTEVQSLLQPWLSSVSRRGIQYSFIPTDSDNYLEYFSS
                     RFGPGIAGAGPATVQLTSRLIPRAAMYNKTETKVIVDALRQVVELDPEASLGCHALNVA
                     NVEHPDNAVLPAWREAIATCNIVTYWDWDISEAEMWEKKDLLVDTLIPGLEEATPGSGT
                     YLNEIDAGWKGDWITELYGENYDRLLSIKNKYDPQHVFYARTAIGSASWTSDATGRLCR
                     V"
     CDS             complement(join(17195..17616,17668..18270,18336..18404,
                     18455..18554,18605..18979))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 147.7; E-value: 8.7e-45)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf10"
                     /product="putative cytochrome P450 monooxygenase"
                     /protein_id="BBM05080.1"
                     /sec_met_domain="p450 (E-value: 7.8e-47, bitscore: 149.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLQLDNITTTDSFDTAPETRPYISIIVLVTGLIAVIVSTLLKEN
                     PLANVPLVTEKAWWDITGKKAKDNFTANARAVIRQGFEKVGFLKPYRIISDQGEMLILP
                     PAMAHDIRNIDALSHAVFMKETTCAEVPGFEPYLESTGTTLLIDMTKTKLISAMKPLTY
                     PLSKTCANACKDLFTSENDWKEVTLKDELLDLVARLSSVIFLGDEEVSQDPAWLKITKE
                     YTVDSFIAFHQLRPYPAFLRSFVAKFLPQARKVLGQLREAESIIEPIIERRRAEKAANP
                     EAYKDRNDSIEWLEQVAQEKGIKYSPPAMQLTLALSAIHTTTDLLTTTMYEILQHPETI
                     QLLRDEVKAVVGDGKLKHSSLYNLKLMDSVIKEAQRLKPVLSINMVRTATEDIDLPDGF
                     HIPMGTRLGVSSHASWDPKIFPNPEKFDPFRFVRLREQPGQENVWQLTTTRPEQIAFGH
                     GQHACPGRFLAANEVKIALCHLLLKHDWELSSITMPKAISHGIMLDSDPTVKVKVRSRV
                     PDVEL"
     CDS             join(19553..19780,19834..21087)
                     /codon_start=1
                     /note="orf11"
                     /product="putative transcriptional regulator"
                     /protein_id="BBM05081.1"
                     /transl_table=11
                     /translation="MGLFSSEKPVQQPPKVPTDEVIPLNAADDTDVLRSVCVVLSYRFD
                     DVLDPEKLKSSYEKLLDRPGWRKIGARLRLNPNGRLEYHIPEKYDETRPIVTWSHVTHD
                     MSITEHPLASKLPRPTTKPAVVGDPHDFDELTCSPDAPKTLDDYLSRDVPQTCLHVVSF
                     NDSTLISISLPHTLTDGTGGAQIYRCWALVLQGREDEVPDFHGYDSDPLATFGDKSSEE
                     YMFAPQLLTGWRKWLFIAYQIYDGWRYKTSSRIMCVPGPYMAAQRKKAIEEIRADTGND
                     KAFVSDNDVLTAWFTRLEAGHFPKNSNLTVRIMNAFALAAVLGNDHLPTTKVFISNAAT
                     EIYTFFTVRELFTKPLSQLAWKIRQSMMTGGTREQVEALQAVKKQTLAREGHTWPMFGD
                     ASMEMMSYSNWTKGKYFETDFSAAMTRVGFPENRRAEKPGYASMVQFNAWSTKFDLRNL
                     MPIMGKDAAGNYWLQGPLRDVVWRRIERELKAAKD"
     gene            complement(21754..30620)
                     /gene="Ev460pks"
     CDS             complement(join(21754..23234,23282..29824,29890..30147,
                     30200..30620))
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (7-442). E-value:
                     1.7e-164. Score: 539.6. Matches aSDomain:
                     nrpspksdomains_Ev460pks_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (550-866). E-value: 3.4e-78.
                     Score: 254.9. Matches aSDomain:
                     nrpspksdomains_Ev460pks_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (941-1110). E-value: 4e-14.
                     Score: 45.2. Matches aSDomain:
                     nrpspksdomains_Ev460pks_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1377-1577). E-value: 1.4e-75.
                     Score: 246.0. Matches aSDomain:
                     nrpspksdomains_Ev460pks_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2115-2289). E-value: 1.6e-51.
                     Score: 166.7. Matches aSDomain:
                     nrpspksdomains_Ev460pks_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2405-2478). E-value: 3.3e-11.
                     Score: 35.3. Matches aSDomain:
                     nrpspksdomains_Ev460pks_PKS_PP.1"
                     /NRPS_PKS="Domain: TD (2583-2815). E-value: 1e-56. Score:
                     183.7. Matches aSDomain: nrpspksdomains_Ev460pks_TD.1"
                     /codon_start=1
                     /gene="Ev460pks"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 213.9; E-value:
                     6.5e-65)"
                     /gene_kind="biosynthetic"
                     /product="polyketide synthase"
                     /protein_id="BBM05082.1"
                     /sec_met_domain="itr_KS (E-value: 3.4e-171, bitscore:
                     559.5, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 8.5e-79, bitscore: 254.9,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.7e-46, bitscore:
                     146.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.6e-07, bitscore:
                     21.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2e-40, bitscore:
                     128.4, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKINEPIAIVGSACRFAGGASSPSKLWELLNNPRDVRSDIPTSR
                     FNKDNYYHPNSAFHGHSNIQHSYLLEEDVAAFDTEFFGIKPVEAKAIDPQQRLLMETVY
                     EGLESAGLTIDSLKGSDTAVYVGLMCGDYEASVLRDLKTAPVYTATGIGRSILSNRVSY
                     FFNWHGPSMTIDTACSSSLVAVHLAAQALRNGESRVALACGSNLLLGPENYIMESKLKM
                     LSPDGRSKMWDKDANGYARGDGVAACILKTLSAAIEDGDHIECIIRETGVNQDGATTGI
                     TMPSATAQRALIEATYEKAGLDLSKAIDRPQFFEAHGTGTPAGDPIEAEAISKAFFGEQ
                     YGTKVAEEPLYVGSIKTILGHTEGTAGVAALLKASLALQNSTVPPNMLLNTLSETVAPF
                     TKNLEILKAPKAWPSVESGQPRRASVNSFGFGGTNAHAILESYEPARLENGGADSSAQF
                     TPFVFSALSRGSLKETLAAYADYIEANPAISLRDLAYTLQARRTAFPYRVSFAAQSADD
                     LVSKIRAEIEGTKTEELGVRLASTNDKRRKIIGVFTGQGAQYARMGAELLEQSATARKM
                     IAELQTHLEQLPEDLRPDFSLEEELRRAKEDSRVLTGAFSFLSTVVQLILVDLLKLAGV
                     EFDAIVAHSSGEMAAAYAAGRLSARDAMCVAYFRGRFASKMVSPNGADKTGAMLAAGMS
                     EEDAVALCEDEMFAGRLCVAAINSSSSVTISGDEDAIDEFKMILDDENKFNRKLRVDRA
                     YHSNHVSKHLADYVELVRRAGVKALEPGEGAPLWISSVYGREVTSDMGLSDEYWGASVA
                     RGVSFYPALKIILEGGEYQAALEVGPHPALKGPASQTIQELGKAIPYFGVLNRGSDATV
                     AFATSLGSLWTRVGGEQLDLTNFEKEVNDNKSALQVLKGLPRYQWNHEGSYWHEPRASK
                     KHKAQTQPFNSLLGTMMPDSAAHHLSWGNLLRASEIEWASGHQVQSQTVFPAAGYICTA
                     FEGARVLAGDRDVRLFELKDFVIHQALTFASDDAGIEVQSSLSDIQNVSKDRLVAKFTY
                     SASIGEEDLDLVAEGELHIVFGPASEATLPKRASKQPHMISVDNERFYTFLATLGYGFE
                     GPFKSLHTLRRKLGSSSCSVHSISREGVFGQPLLVHPAELDGGIQSLILAYSYPDDDQL
                     LNMHLPTSMKSIRVNPTLCQSMTDITTDGRLGTRRSAGFNGDVSLFTNDSACAAIQIQG
                     LELKPLGALTAKDDRKVFSKYEWVKNRLDGDLAADDTNVTKHHEDVLEGLERISTFYLN
                     KLDAEVPMDSPLRKEGPHMHYLNYAHHIVELIQNGEHKVAKHDWLSDSLEDLHRKTGHL
                     KDLIDYDMMHLVGQQMPRVLRGETNMLEEMRVSNILDNYYKGAFGSREAGLWIGKIISQ
                     LAERYPHLNILEVGAGTGGATTRVLQGLNNKFLSYTFTDVSSGFFEGAAEMFSEQKDRM
                     VFKTFDCGQDPVAQGYAEGTYDVIVAFLVIHATPDLDLTMRNIRKLLKPGGFLIVGEGT
                     NNGQPYGSAGFIFGSLPGWWLGADSGRPLSPFVSYSEWERLLRGSGFSGIDSTAPQAFQ
                     DVLGMTVFAAQAVDDRVNFIREPTNPEVVAKSAAAIEYPIEKLVVIGGSTDKTRSLVSS
                     ITETLKKSAVNLYTFETLTGVDFSLVDANAIVVSLSELDKPVFEDLTPEEWAAFKTLFS
                     CPTKLFWVTSGRLSEVPFSNMTVGFARTAVFETPALRFQNVDFTDLSTVKAQDLVEKVL
                     RFHASASTLPPDVKQLAWPLEPEILVKEDGEELVPRLRHINARNDRYNSARRPITNETD
                     ITKSPAALFNDGEGWKLKELSPWAIPAETPETITLEVSHAVLSAVRTSYGHQFLVFGTD
                     SKTQGRFMALVPSLLSVVTIAKESAVPVPKAAATDAELQASLAACLISMAVVDPLVDGD
                     TLVVHNATELLANTISTHAASKKVHAVFVADSSNADAPEAWAKLEPYMTQSEIADILPA
                     NTACFVDFSVQGSENASSIIAGLPIHCRKENVSTLYSPIGWESVSVSAASALGQLLQRA
                     WFYAQQETLAHKKDAIAPQTVSIADLLEGSNPEDPATVIDWTLSKTHPVHVSRLDSGAF
                     FKGDKTYWLCGLSGALGVSLVDWMIERGAKCLVLTSRNPNISPDWIAAHKKNGVNVTIV
                     PCDVTNEPALRAAHKFIVETQPPIAGVLNGAMVLRDVSIANMSFELMSDVFRPKVYGSI
                     HLDRIFKDTPLDFFILFSSINCVIGNLGQANYAAANTFMCSLAAQRRKRGLAATALNVG
                     AIIGAGYMERESSKALDLTVSKMALMHLSEQDYHQLFAEGIDAGRPDSVDEAELTTGLL
                     DIPAAEDDENTPKWHSNPAFLDFIVHQVEKNGADAGNEVIASVQDQLAACKSRTDVLAV
                     VKARFAMQLRNVLQMTTADEDLMALRSRDIGLDSLISVDIRSWFLKNFEVSVPVLKIMG
                     NDTMAELADLVADQCPESLLPGLGGDGEAPVPVEDTPAVSVTPTVVVKAADDAASSSDS
                     NDGTPAESVHGGSTGRTTPVTMEPPQMVKGPLRIDWSKEIVLPQAAKISTERAPAARPQ
                     NVVLTGVSGLLGRNLLNSLLADSSVKKVFCIAVRRLNERINELPKDARVQYFAGDLETP
                     RLGLSERDATEIFSQADVVIHNGADTSHLKFYPEIKAANTGSTKELISLCISRKVPIHY
                     LSTVGVALFGNYKSFPEVSVAEHQPPVDGSHGYVAAKWASERLLEEVKKEAGLNVWIHR
                     PSTIIREGSDATNAAAQIDWMNALVEYMRKTRAVPVLKNLRGALDFVYVKNATDSILST
                     VFSNKQQGVVYTHQVGDIVAPLEDLKEFVAKDTGAVNVQELPVELWSQKAVEAGLNRGV
                     AALIDSMDDPGQPHYPRMLKAAQ"
     aSDomain        complement(22012..22707)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Ev460pks_TD.1"
                     /evalue="1.00E-56"
                     /label="Ev460pks_TD.1"
                     /locus_tag="Ev460pks"
                     /protein_end="2815"
                     /protein_start="2583"
                     /score="183.7"
                     /tool="antismash"
                     /translation="VVLTGVSGLLGRNLLNSLLADSSVKKVFCIAVRRLNERINELPKD
                     ARVQYFAGDLETPRLGLSERDATEIFSQADVVIHNGADTSHLKFYPEIKAANTGSTKEL
                     ISLCISRKVPIHYLSTVGVALFGNYKSFPEVSVAEHQPPVDGSHGYVAAKWASERLLEE
                     VKKEAGLNVWIHRPSTIIREGSDATNAAAQIDWMNALVEYMRKTRAVPVLKNLRGALDF
                     VYVKNATDSI"
     aSModule        complement(22012..30599)
                     /complete
                     /domains="nrpspksdomains_Ev460pks_PKS_KS.1"
                     /domains="nrpspksdomains_Ev460pks_PKS_AT.1"
                     /domains="nrpspksdomains_Ev460pks_PKS_DH.1"
                     /domains="nrpspksdomains_Ev460pks_cMT.1"
                     /domains="nrpspksdomains_Ev460pks_PKS_KR.1"
                     /domains="nrpspksdomains_Ev460pks_PKS_PP.1"
                     /domains="nrpspksdomains_Ev460pks_TD.1"
                     /final_module
                     /iterative
                     /locus_tags="Ev460pks"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(join(23023..23234,23282..23288))
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Ev460pks_PKS_PP.1"
                     /evalue="3.30E-11"
                     /label="Ev460pks_PKS_PP.1"
                     /locus_tag="Ev460pks"
                     /protein_end="2478"
                     /protein_start="2405"
                     /score="35.3"
                     /tool="antismash"
                     /translation="VKARFAMQLRNVLQMTTADEDLMALRSRDIGLDSLISVDIRSWFL
                     KNFEVSVPVLKIMGNDTMAELADLVADQ"
     aSDomain        complement(23637..24158)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Ev460pks_PKS_KR.1"
                     /evalue="1.60E-51"
                     /label="Ev460pks_PKS_KR.1"
                     /locus_tag="Ev460pks"
                     /protein_end="2289"
                     /protein_start="2115"
                     /score="166.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="TYWLCGLSGALGVSLVDWMIERGAKCLVLTSRNPNISPDWIAAHK
                     KNGVNVTIVPCDVTNEPALRAAHKFIVETQPPIAGVLNGAMVLRDVSIANMSFELMSDV
                     FRPKVYGSIHLDRIFKDTPLDFFILFSSINCVIGNLGQANYAAANTFMCSLAAQRRKRG
                     LAATALNVGAI"
     CDS_motif       complement(23679..23789)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Ev460pks_0008"
                     /evalue="2.40E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="Ev460pks"
                     /protein_end="2275"
                     /protein_start="2238"
                     /score="68.4"
                     /tool="antismash"
                     /translation="LDFFILFSSINCVIGNLGQANYAAANTFMCSLAAQRR"
     CDS_motif       complement(24060..24158)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Ev460pks_0007"
                     /evalue="3.30E-12"
                     /label="PKSI-KR_m1"
                     /locus_tag="Ev460pks"
                     /protein_end="2148"
                     /protein_start="2115"
                     /score="39.0"
                     /tool="antismash"
                     /translation="TYWLCGLSGALGVSLVDWMIERGAKCLVLTSRN"
     aSDomain        complement(25773..26372)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Ev460pks_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="1.40E-75"
                     /label="Ev460pks_cMT.1"
                     /locus_tag="Ev460pks"
                     /protein_end="1577"
                     /protein_start="1377"
                     /score="246.0"
                     /tool="antismash"
                     /translation="ILDNYYKGAFGSREAGLWIGKIISQLAERYPHLNILEVGAGTGGA
                     TTRVLQGLNNKFLSYTFTDVSSGFFEGAAEMFSEQKDRMVFKTFDCGQDPVAQGYAEGT
                     YDVIVAFLVIHATPDLDLTMRNIRKLLKPGGFLIVGEGTNNGQPYGSAGFIFGSLPGWW
                     LGADSGRPLSPFVSYSEWERLLRGSGFSGIDSTAPQA"
     aSDomain        complement(27174..27680)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Ev460pks_PKS_DH.1"
                     /evalue="4.00E-14"
                     /label="Ev460pks_PKS_DH.1"
                     /locus_tag="Ev460pks"
                     /protein_end="1110"
                     /protein_start="941"
                     /score="45.2"
                     /tool="antismash"
                     /translation="LLGTMMPDSAAHHLSWGNLLRASEIEWASGHQVQSQTVFPAAGYI
                     CTAFEGARVLAGDRDVRLFELKDFVIHQALTFASDDAGIEVQSSLSDIQNVSKDRLVAK
                     FTYSASIGEEDLDLVAEGELHIVFGPASEATLPKRASKQPHMISVDNERFYTFLATLGY
                     GFEGPF"
     CDS_motif       complement(27525..27596)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Ev460pks_0006"
                     /evalue="1.10E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="Ev460pks"
                     /protein_end="993"
                     /protein_start="969"
                     /score="27.6"
                     /tool="antismash"
                     /translation="SGHQVQSQTVFPAAGYICTAFEGA"
     aSDomain        complement(27906..28853)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Ev460pks_PKS_AT.1"
                     /evalue="3.40E-78"
                     /label="Ev460pks_PKS_AT.1"
                     /locus_tag="Ev460pks"
                     /protein_end="866"
                     /protein_start="550"
                     /score="254.9"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mxmal"
                     /tool="antismash"
                     /translation="VFTGQGAQYARMGAELLEQSATARKMIAELQTHLEQLPEDLRPDF
                     SLEEELRRAKEDSRVLTGAFSFLSTVVQLILVDLLKLAGVEFDAIVAHSSGEMAAAYAA
                     GRLSARDAMCVAYFRGRFASKMVSPNGADKTGAMLAAGMSEEDAVALCEDEMFAGRLCV
                     AAINSSSSVTISGDEDAIDEFKMILDDENKFNRKLRVDRAYHSNHVSKHLADYVELVRR
                     AGVKALEPGEGAPLWISSVYGREVTSDMGLSDEYWGASVARGVSFYPALKIILEGGEYQ
                     AALEVGPHPALKGPASQTIQELGKAIPYFGVLNRG"
     CDS_motif       complement(28506..28604)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Ev460pks_0005"
                     /evalue="9.50E-09"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="Ev460pks"
                     /protein_end="666"
                     /protein_start="633"
                     /score="27.8"
                     /tool="antismash"
                     /translation="GVEFDAIVAHSSGEMAAAYAAGRLSARDAMCVA"
     CDS_motif       complement(28806..28850)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Ev460pks_0004"
                     /evalue="1.20E-04"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="Ev460pks"
                     /protein_end="566"
                     /protein_start="551"
                     /score="14.8"
                     /tool="antismash"
                     /translation="FTGQGAQYARMGAEL"
     aSDomain        complement(join(29178..29824,29890..30147,30200..30599))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Ev460pks_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.70E-164"
                     /label="Ev460pks_PKS_KS.1"
                     /locus_tag="Ev460pks"
                     /protein_end="442"
                     /protein_start="7"
                     /score="539.6"
                     /tool="antismash"
                     /translation="IAIVGSACRFAGGASSPSKLWELLNNPRDVRSDIPTSRFNKDNYY
                     HPNSAFHGHSNIQHSYLLEEDVAAFDTEFFGIKPVEAKAIDPQQRLLMETVYEGLESAG
                     LTIDSLKGSDTAVYVGLMCGDYEASVLRDLKTAPVYTATGIGRSILSNRVSYFFNWHGP
                     SMTIDTACSSSLVAVHLAAQALRNGESRVALACGSNLLLGPENYIMESKLKMLSPDGRS
                     KMWDKDANGYARGDGVAACILKTLSAAIEDGDHIECIIRETGVNQDGATTGITMPSATA
                     QRALIEATYEKAGLDLSKAIDRPQFFEAHGTGTPAGDPIEAEAISKAFFGEQYGTKVAE
                     EPLYVGSIKTILGHTEGTAGVAALLKASLALQNSTVPPNMLLNTLSETVAPFTKNLEIL
                     KAPKAWPSVESGQPRRASVNSFGFGGTNAHAILESY"
     CDS_motif       complement(29520..29564)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Ev460pks_0003"
                     /evalue="1.60E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="Ev460pks"
                     /protein_end="328"
                     /protein_start="313"
                     /score="11.0"
                     /tool="antismash"
                     /translation="FEAHGTGTPAGDPIE"
     CDS_motif       complement(29772..29810)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Ev460pks_0002"
                     /evalue="3.30E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="Ev460pks"
                     /protein_end="244"
                     /protein_start="231"
                     /score="10.8"
                     /tool="antismash"
                     /translation="WDKDANGYARGDG"
     CDS_motif       complement(30017..30064)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Ev460pks_0001"
                     /evalue="3.60E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="Ev460pks"
                     /protein_end="184"
                     /protein_start="168"
                     /score="21.9"
                     /tool="antismash"
                     /translation="GPSMTIDTACSSSLVA"
     CDS             complement(join(32072..32467,32515..33254,33305..33503,
                     33553..33604,33655..33731,33782..34078))
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 335.7; E-value:
                     5.4e-102)"
                     /gene_kind="transport"
                     /note="orf12"
                     /product="putative transporter"
                     /protein_id="BBM05083.1"
                     /transl_table=11
                     /translation="MNDEPVALQTWSRPNTRESDARTQNTEESSRAPWTQQEHGSTARV
                     IEKPGDEESSAADPPAEAAAVQAPGVTGFKLFGILASVTLSAFLMLLDGSIIGVAIPNI
                     TSQFHSIHDVGWYTAAYQLSSAALQPLSGKIYTSYNTKWTYLFFFFLFEVGSLICGVAN
                     SSSTLIGGRAVAGIGSSGLLNGGMTIIAGAVPLEKRPVYTGVYLGISQLGIVCGPLIGG
                     ALTQYTTWRWCFYINLPVGAVVAVLLLFLRVPELTKKEPFSLALVKKTLPDLDLIGFTL
                     FAPAAIMALLGLYYGGNEYAWDSSVVIGLFVGAAATITVFGIWEWKMGDRAMIPTSMVS
                     HHIVWTSAINGGTLVASILTASQYLPIYFQGVRGYGAAMSGVNTLPGILSQLLTVIISG
                     GVVQKVGYYLPFAAAGSAISAVGNGLVTLFRPDTPTDKWIGYQIVLGSGRGIGMQMGII
                     AIQNLLPPEKIPVGIAFMIFCQNFAGAVFVVVGEVIFTQELVKEIVKYAPSVSVEAAEA
                     AGASADSVRTLVPEGSPELAGVLMAFSNSVDKVFYLLMALCLLGFVAAFGMGWVDIRKN
                     KKPAAEEEDK"
     CDS             complement(34933..36246)
                     /codon_start=1
                     /note="orf13"
                     /product="putative transcriptional regulator"
                     /protein_id="BBM05084.1"
                     /transl_table=11
                     /translation="MSDQQTQAQQPPKKRAACDRCRTQKLRCLRVSGHPNDHCIRCVRS
                     QMECITSSSKRPGRPRNSTNTPRQQQPTPSPNTGIETNPALPAIDIPPQSLENVDDWFN
                     FGSLDTDYEICSAPWTSVDSGFESGFPMEGVATSMSSLSTPPLQTASTPAFLTTMPTHT
                     PIHDHFQDDPCDQLPLPGPQPFAANFDHGLHLSQLQRELSKQLYTLTSMPWDMTKVMQL
                     TCFQAPGTSAPSSPSQDDLKSNPLAKIAKTSAEFAQLLCSVQSPIAGDGGSNTSKASSP
                     LSSIHPRLSMPDLLTILSCHMLTISIYDSIFSHFTEQASHNPGAVNIVLQSAPKLYLGG
                     IAVPPRLELLSHLLYCITASQLRPIEMLLGLPDECCVSLKRNSASKDKQTGLFSGQSGQ
                     LLFSTLMQVETERATEDRGGLGVIESLKEKIRLIQGLE"
ORIGIN
        1 gattcttgtt attgaaggct ggttgtatct actccaaggc agttcacagt cgcgtattta
       61 tattccccag ctcagcagca ccgtcggcct tgacggacat acagatgagg taaactccgt
      121 gccttaatac ttagaatcta atggaagcag gtttgagctg caattcggtt gtaacgcgtg
      181 tgatgtcgta gtacctggac cagttctata gagttttgtg gatctgaata aattcagtta
      241 agcgcttatc gagattcaca ccaatcatac tgcctaaaac acgacgcagc caatgaacct
      301 agtgagaagt gggccatcac gagtcattcg aggcttgctt ctgtcattct tttggtgctt
      361 tgtggctcta ctcagccagg gccaggttct tcttctgcgt gctcttcatc cactttctgc
      421 acatcaacca tggccctcaa acgcaacagc ccccgccatg tcaagtctgg ctgtaggacc
      481 tgtaaaatcc gacgcgtcaa atgcgacgaa cagcggccct cgtgccacaa atgcgtggac
      541 tcaggacgaa cttgcgatgg ctatgggatc tggtcgagtc ctcctactcg cgtcccagct
      601 cagcaactgg tctaccctcc tcgaaccctg cctggccttg gtttatcgga gaaaaaatac
      661 attgatcgtt accgaaatct cttgacgcaa aagcttgccg agccctttgg ctcctacttc
      721 tggaactcgg tggttctcca gctctcgcta tcagaagctg ctgtgctcca tgccaccatt
      781 gccctgactt ctgcccacga gctgctcatg caaggtcgca gcttcaatga accctttctc
      841 ctgcgccagt acaatcgcgc catccaagcc ttgacctaca agaccacctc tctgcgcgtg
      901 actattgtct cgtgtgtcgt cttcctctgt attgagatca ttcgaggtaa tccaattgcc
      961 atgcaagctc acttcgacgc tggtatcaaa ttattgcgtc aactgcaaga tggcaagtgc
     1021 aacagcactg tcctcgtcag acacaaccct gaaggcttcg atgaccatct cgtcgacgtt
     1081 ttcgcaaaac tcaatttgca gttcctcatg ctaggccatg catcgcaaca aaaggaggct
     1141 ttcgtacctt ctttccagta cggcggtcgc attcactctc ctcgtacttt ctttagcgtc
     1201 cttgatgtcc gacagtctat caatccgatt ttgctgtctg tcatttatct catgaaggag
     1261 cgtgagcgag agaccttgtc gactgacaaa caccccccgc gaccgagcgc agctctgctt
     1321 gacaagcaaa gtactcttca agcggccatg tcagaatgga ttgagagcta tgaggcctcc
     1381 atcacgtcgc tgtctgccaa aatctcacgg tcggagcgat tcggtctggt gcttcttcgc
     1441 gtatatgccg acgttgctac gatcctgtta gccacctgct tttccattag agaaacctcc
     1501 tacgatcctc atgtgtcccg gttcgaggca atcatcaagc gctacagcga tttccatgag
     1561 agcgtgtaca ggtcggaggc caatagctgc ccagcacatc ccttcttcac caccgacacc
     1621 tgtcttttcc caccgctgta tttcacagct ctcaagtgtc gcaattcaac catccgacat
     1681 cgggcgattt cgttgctgaa cgagtatgat catctggaag gcccgtggac tggccccatg
     1741 gtcgctgcgg tcgcaaatca cgtcgtcagc ctggaagaaa atcattttga gaaggccatg
     1801 cagtcttcag gtggacaatg tgattctggc cccattgtag ttctccccga gttctgtcgc
     1861 atccactgtg tcgaatgcaa gctggacggc cacacaaaga ccggcgagct gacgctgagg
     1921 cgctttcggc atgagctggg aggaggcgga ggctggtcga tcagcaagtc cactgtcctt
     1981 ttcaaaatca aataatcttt atttattcgg ggttggtgta atgcttactg cagtgaaatt
     2041 cccgagccaa caatggcccc aattgctggt aattgccgac accgacgcag cctcggggga
     2101 agcttgggct gagctgtgtc gatcagacag attaacaaga gtcagaaagg tatatagctt
     2161 tggagagacg gactgaatca gctattcatc ctcaagcatc tacagaatta cacagtcgcc
     2221 atgaaccccg tcaacaccaa gccctatcaa ctccccgccg acgccacctg gtttggtatg
     2281 tctcttctca ctttcaaccc atttcatagc taattataca gtcaccggtt gctctagcgg
     2341 tatcggccgt gccatcgctg aacatgtcgc tgctcagcct ggccaccgtc tgattgccac
     2401 tgcgagagac cctgccagcc tctcctacct ccaagacagc gcctctatcc tgaagctcgg
     2461 tctcgatgtc accaagccgg agtctgttga cgctgccttc aaggctgctg ctgctcactt
     2521 tggcgacagc tactacctcg acgttgtcgt gaacaacgct ggatactctc tctccggaga
     2581 caccgagtct gtgactgagg gcgagatgca cgaggccttt gagaccaact tctttggtct
     2641 cgtccgtgtc tctctcaagg ccatcgaggt tatgcgccag tccaaggaga agcgcggtgg
     2701 tctgatcttc aacatttctt ctctggctgg tatctgcgcc ttccccggcc acgccttcta
     2761 ccacgccagc aagttcgccg tcgagggatg gagcgaatct gttgctcgcg aggtccaccc
     2821 tgactggaac agtatgtctt ttatatctct ttgtatggcc aactgctaag ttattctata
     2881 gtcaacttct gcatcgtcga gccttcggcc gtcaagacca acttcgagac caccagcaag
     2941 aagcgcactg ccccccacga ggcctacgcc ggcgccgaca tgcccgcccg ccagctcgag
     3001 atgttcgtca agaagggtct tgctgccggt gttggtttcg agcccagtgc tgtggccaag
     3061 gtgctgtacc aggtcgccag ccgcaacgag aaggtccccc tgcgtctgcc tctgagcgcc
     3121 actgctgtca agctcatcac tgctaagctg cagggccagc tgcaggatct ggagaccact
     3181 gctgagctga gtgctattga tgttggccag gctcagttca aggtttaagc tgttttcttt
     3241 tcttagttcg ctggtagttc taggtgcaat gaatgatttt atgacgacct ctcttcacta
     3301 tgaaataaat tctctgaaca tttactatgc ccttggcttg cagttagaac aagttcaaag
     3361 tactttcaaa gtactttcgg gatgattttg tatatttgtc tgcgtcgtct tcgttcgaca
     3421 tgcccgatcg tggccgttga agtgctgata cccgagccct acctcacagt attcgctacg
     3481 gtcgcaaatt cgacgcacca gatatttgac attaaaaaca gcttaacaag taaattgaag
     3541 tgcattacta ttcgtattcc agttattaga tcttcgagtc taccacaaac gcttccatcg
     3601 gaccttcatg tctcggtcgg gcggaatgcc cacagcgcca atatacgact gatcattctg
     3661 cgctggacga tcagacttgg tgccatcagg atgcacccag tcaatcagtt caatttcaaa
     3721 tctcgtaacc agagcagcga tggtcatcaa aatctcttgc ttagcgaaaa cacgaccagg
     3781 gcagatggaa gggccaccac ctataatatg ttagtcggat caattagggt tgaagaagag
     3841 cagaaacata ccaaatggga agaatgaagt agttcttcca gccattgtaa actcagcctt
     3901 gccattctca tgcttcaggt tcctgcctgc ccagaattga gaggcaggat gaccttcaga
     3961 ggcccagact gcttcgttgt actggccgat ctggctgggg gcttggatga gagaaccagg
     4021 agtcaaaaga tgcccatcca gcgtgatagg ctgagtaact tcacgagtga cattgattga
     4081 tacatgcagg cgcagtgtct cgatatagac agattgcaga agaggcattc caagcagctt
     4141 ctgagggttg aagacgcgct cgccggtcgc agggtcgaca gtgctggcag caatacattc
     4201 ctcatgcaca gccttgtaca gctcaggatc tgcaatcaac tccatcatgg cccatgtcga
     4261 cagcggtaca gagttggcat tcgtgccaaa gatgaaagtc gcaaccatac cagcggtggt
     4321 ctcaggcgac aggttgttct ttgcccatcc gatgagctcg cgtgccattc tggagccata
     4381 gtgaggctcc cattcagagt caatatcagg tccattccag tcaaactcct tttcagcaga
     4441 atcaaggtag cgacgacaca ttccgtggaa ctgttcacga atctcccagg gcttggggtt
     4501 cacccagcga ggcaaccccc acataagacg cggtgccaga cgagcaaact cccacatcgc
     4561 aggccagaat cctgggttca gcttcacaat gcgaggtccc ataagtgcaa ccagggcagc
     4621 ttcagccatt tcactctcga agaactcgct gagccggatc tcctgccatt cgccgagggg
     4681 ttgtttcttc agacggtcgg agaacagttc gtagtacttg tcgctcaggg cattcgcatg
     4741 gtccgctcgc tggaggtatt ccgagtagac atggtgctgt ccatgccaga gtcgcggctg
     4801 tcctggcttg acgtcgtgtc caggcactgg gttcttgctg cgtccagact tgtcgttggc
     4861 gaatttggac acttcgtcct tgcgcgcgcc ccagacgttg gccatgacct cgaggaagaa
     4921 gacatcgggg ctgatgctgt gtgagggctt gttgatggct tggatatttt gttcgccaga
     4981 gaccatgtag attttctttg gtcccagtcg gaatttgacg attttgctct tgcgttgggc
     5041 ggatctatac gattaaccat tagtgccatc ttgggcctat gtagtagctc tgaacttacg
     5101 cgactctctg caagaaacca tgcatatcag tcatgtactg ataagtgttg gcaatcatcc
     5161 atcctcccag cgaaggtggt tcttttgcgc ccttgccaat ccatttggga atgaagatgg
     5221 cgagcgcaat gcacgctgcg acaccccaga cgagaggtcc aagttcagcg atcattttgg
     5281 tttatccagt gtaaatgccg cggttagtaa cgcgacccct cctgtttcga ctttattcat
     5341 ttttaagtac gaatagttct ggccccaaga gctgcccaga ggctgacagc agctgcgccg
     5401 atcgttcgga gtaatcctca taatggccga tctcgttatt cccgattcaa ccgtacgatt
     5461 ggattcaatt cggggcggaa acggaatgtc agtgctttgc agaattgttt attactgtgg
     5521 tcgagtatgg gctgatcatg gagactccca ttcgctatac agcattgtct tgcatacgcc
     5581 cttgacatac accaacaatg gcgccaccaa cacagacagc catcgtgcaa atcgctaaag
     5641 gcgactcatc agagattcct cttgtcgtca gcaagtcggc tcccattccc caggtacaat
     5701 cagagaacca tgtgctggtc aaggtgctgg cggtggcgct gaaccccaac gaccacaaga
     5761 tggtcaccca tttcaacacc gcaggcagta tcgcaggatg tgacttctgt ggtgttgtcg
     5821 caagcagcaa tgcacccctt ggattgaccg agggaacaag agtctgtggt gctctgttcc
     5881 cctacagtcc tgccgacccc gacaacggat cctttgcgca atactgtgtt gttgatgcgc
     5941 gcttgctggt caaggtccct gatacctgga gtgaccttga ggctgcttct ctcggtgtcg
     6001 gctggtcgac catttctctt gcattctctg atcccaatgc actgggactg gagggtcttc
     6061 ctaccaagcc tacgcatcag aacaaggagc ctgtgctggt ctatggtggt ggtactgctt
     6121 ctggtacatt ggcatgccaa ttgctgaaat tgtacgttta ctcctggttc acccttgacg
     6181 tatgttaaca aatacaggat gaactacact ccaatcgcaa tcgcctcgaa ccgctcagcc
     6241 gaactcgcga cagaatacgg cgccgcagga acagcctcgt acacttcgaa agactgcgtc
     6301 gacaccgtca agtccatcgc cggcaagccc attcgcaaag tcctcgactg catcacagat
     6361 gccgagtccg ctgccatgtg ctacagcgcc atggctcgta cgggtggcaa ttacgcctgt
     6421 ctcgaagagt gccctgaggc ctggagaagc cgtcgcattg tcaaggtcaa ggaggttatg
     6481 ggattccagg tgctcggagt ggatatcaac ctcggcgatt caacatacac aaggcttggt
     6541 gaccagaagt tgttcacaat tggaacacag tgggcgcgtg agtttgagac gttgatggca
     6601 acgggccagc tcaaggcaca cccattgcgc gaactaccag gaggcttcga tgcaatcatc
     6661 gaaggactga acatgctacg caagggcgaa gtgcgcggac agaagttggt tgtgaagatt
     6721 ccccagaatt agttattccc tagatctatc tatgcatttt ccttgttctt gaactgagtc
     6781 caaaagtcct tcttccacgc attcaccagc gccgtaactg taggattgcc aaagggggcc
     6841 tgctgtgtcg caaagaatcc agcaacgcgc aggtctctgt ttacccacca gacaatgttc
     6901 gatgcacctc cccagcctag tatgcccttg ggttgtctaa tctcagctac atcgcctgtt
     6961 gtcacgatac ctccaagtcc gtggttgatc gcgtcttctg cgatgggacc agagacggta
     7021 tcccaggcag gacgcaaacc caacatctgc tcgacgggca ctgacttggg ctgtagctgg
     7081 ggaacgaaca tctctgcaat gattccaggg ctaagaagct tgggcgagtc tgagatcaaa
     7141 tcggccagca ccgcaacata gtcctttgcc gtgcaagaga gaccactacc tccgtcctga
     7201 tcttcagggt tatcaaacgc ccaggtgttg tttggctgaa ggcgaccgtc gggagtcctc
     7261 attgcgcctc ccatggcgcg agcattgtat tcagggtgcg tagcgatgtt gaagcagggg
     7321 aatggcgcag agagacccag ttttttccag atgttctcct caaagtactg ctccagagtg
     7381 attccaccat taagacgact gacggtgaca ccagcccagt ccaaactgca tccatacaac
     7441 catccagttc caggctcgaa gacaagcggc atctcgtatc gttcagtgat gcgcagcgac
     7501 ggtttctctc cagcggcagt cttcgcctcg gctctcatcc tgagcaatcg gtgggtgaag
     7561 cgatatccga aaccagaagt gtgcgtaaga agatgtcgcg cagtgatagg aaccttgcta
     7621 ggttcatgga caaactccaa atccttgacg tcgatgagga tctgcttgtc cgcgagctca
     7681 ggaacatgct tcccaagggg ctcatctagc ccgataagtc ccttgtcgac gcattgaagc
     7741 aaggcgatac tagtaatgag cttcgtggcg ctggcgacct tgagcacgac gtcttcggta
     7801 agaggggcag cattgggctc gacagaatcc caaccagcga ctttgctgta aatttcattt
     7861 cctggactgt cagcttacgt attgtgtcaa agggacatac ataccctgtt tatccacaca
     7921 tttgaagata gccccgtgca ccttggggtt ctccttcttg gtgtagtcgg cgaggagagc
     7981 gtcaaagtcg gccatgatgc gcttgtccag agcttgccca ggagcttgga gtaggattgc
     8041 agagacacca agcctcagcg gggtagattc gaaggattgg aatgcttctt tgtttggaga
     8101 ctcgctagtg gcacaggctc tgtggctctt tccacagggt acacttcctc tttaggtgga
     8161 catggctctg tactaagccc gtctaatcct gtaagaaggc cacttgccct gtaacaggaa
     8221 tgaatccctt tgtgtagcgc cagtttctgc ctgaacccat ttgttcgccc gaaagtgtcc
     8281 aatcaatgcg cattcggtgg gtttcgggcg tttcgggaat atcagagcta tactatcctc
     8341 atgttggggg ccattcggat tgccgggatc tatacagcac attaaaacca ccatgacctg
     8401 cataatggtt ctatacacat caccccttat acgaccaata cgcaaatatg tctctcgacc
     8461 gctacgctgc ttttcacgct gaaactcccc aaggccgagg cgatggccgt ccaaccgccg
     8521 agcagatcct ccgcgaccag gaaccactgg gcgactggag cgacaaggtt attctcatca
     8581 ctggtggaac agctggtcta ggtgctgaat cgacacgcgt actgcacaag accggcgcaa
     8641 agatcttcat catgggccgc gacgccgtca agggccagaa attggccgac aacatctccg
     8701 ccgtcaaccc gcagttccca ccaatcgaag tcattacaat ggaccagagc agtctgcaga
     8761 gtgttcgcga tggtgcagcg gaattcctca agaagagtgg taggaagttg aacgtgttta
     8821 tggccaacgc cggtattgtt gcttcaccag tcaaggagac caaggatggc ttcgaggctg
     8881 tctttgcgat caactatctc tcgaccttcc tcctcactca gctgcttgcg cctgctctcg
     8941 aagcctcgac aactcccgaa tttaaatcca gactcgtcgt cgtttccagc gccggtcacc
     9001 gcgcaggtaa tgtcgatccc gaaaagtaca actttatggg cgagggttac gacccatcca
     9061 aagcctacgc gcgcagcaaa tccgctgcga ttctcatggc caacgaattc gagcgcaagt
     9121 atggcagccg cggtgtccac gctctgagtc tcaaccctgg tatcattatg gacactgaaa
     9181 tctctcgcga tatgcctgga accaaggagt cgcgccgccc aatgtactac aagatggagc
     9241 cgcttctggc aagctgggag aaggacgttg aacagggtgc tgctacccag gtttgggcgt
     9301 ctattgctaa ggaacttgag ggcaagggag gactgtacct tgacgatgtc caagtagcta
     9361 aggaggccaa gtttgagggt cagatgtgtc ttccgggttg gaagccctgg atctgggatg
     9421 aggaaatggc tgctagacta tggaaggata gtctcgagat ggttggactt gcttagattg
     9481 atagcacacg aagatacttt tcttattgaa tgaattgaat caaaacatgc attgacgtat
     9541 ctatgttatg cttaatcgct agcagctact ctagccagca tgttcgcgtt gtagtagaat
     9601 ggaggctcac tatccaagcc cacagcgtgc aatccttcga atccagcttg cttcagacga
     9661 cgatcccatt ctgcaggagg aatgcatggt cctcctgcgc gtccgtctgc ctcacctagc
     9721 caccatccgg ggagaaggcc ctgcgaaggt cagtactgac ccctttgtac actggggacg
     9781 atactcacca ccatgaagtc cacgtacttg cccgggggcg acagctcctg gttgaagagg
     9841 aatcccttgg gctggagaag ggtgcgaaca ttcttcagtg tttccacaag gcacggcgtg
     9901 gcgtggagga cctatttccc gttagcatac catttaatcc aacttattgt cttcatcact
     9961 cacattggat gcaatgacaa catcgtaggc gcctgcttca aagccctgct caacggggtc
    10021 cttggaaatg tccagcgcac ggtattccac attgtcgtag gcctcgaacc gacgctttgc
    10081 cgagtcaaag aataagggcg agatgtcagt gaagacgtag ctgctgtaga gctgctttcc
    10141 tgcgtctgga ttcaaccctt caaagacacg agcagttgtc cctccagtac cagctccaat
    10201 ctccagaatg cgcagtccag ggtttgtccg gcccataaga ttgatcagag gacgcacttc
    10261 agacagactg tttgcccagt catagaactt ctccagcaat ccatccttca gcaagacctt
    10321 gacaagcttg acccgtccct ccacaatatc aacaacattg tcatagaccc tccacggccc
    10381 ctcaataaca ggccacagat aagtatcctt gaccctttct ctcatctcat tcattgcctt
    10441 caagcgctcc ccatcactca gcgccacgag atcgcccgaa tccggaacct gtgggtaacc
    10501 aggctgcttg aagcgctcat actcacttgc aagccagttg cggtactttt cgaagtgggg
    10561 cttcgtgcag gttgcgctct tcagcttctc ttgcatctgg attgcgcaga gcacccacat
    10621 ccgcgcgatc atttcttgct cggattgcga ctcgcgcgtt gggtggagga gttgcgagac
    10681 gggggtggga gttgagtctg gcgtccattg taggtcgact gtttgccagt tggagagatc
    10741 gatggaggcc atggtgtgga tgtcgtgaat cgatgtactc aacttcggtc aaagacagta
    10801 gatattgaag tggattcaca agcgtctaca tcaactttgg tacacgactc aggccatctt
    10861 ttagggcaat gtctgtcaga tcgatccttg taaatcccga ttcacagcac cgatagtcta
    10921 cctggatcgg tagtttgcta gctgagaatg caattattcg gagtaatcct cgggagtttc
    10981 gtctatcctc cgctaggggc aggattgtac gccttgtcac tgccaggccc tcgaggttga
    11041 ctatagaatt tgagtgtaca ggctaggggc tatgtacgtc aaggagtagt agtgagaagt
    11101 attgctgtat agattactat gaactattga cagtctgcta attgaacgca tcacaaggcc
    11161 agctaacgcc aaataacgta gaaaaaaaaa taattcataa tctagtcaaa aatatccacg
    11221 gcatatcgcg tgttcttcag tccttcgaac cactttgcta cctcctcctt gctcgtctct
    11281 tcgcctttct ccttcttcgc atcgtagaga atctcaatca tcatctcttt agcagactcg
    11341 cccatagctc gtccaccaca gatgtagatc atagcaccct gatcccagag cgacatgatc
    11401 tcctttctct cctgccacag ccggtcctgg acgtacttgt gtccctcgct ggcttcaacc
    11461 tggcgactaa aagtccttcg aacattgacg actccactag actcccagtt gtccaagtca
    11521 cttctgtaca agtcatcctg tcctggttga cggcatccga agtagagagt agcaggcgca
    11581 atcttgcgac cggcaccctt cattcccgct cgctcttgaa tgaaacctcg gaaaggtgca
    11641 acaccggtgc cagcggcgat cataaccatg gacgtcctcc cagcgtcggc aggaaggtgg
    11701 aatgctgcat gggatgggcg cacagcaacg tgcaccacat caccagcttg aagagtagac
    11761 atgtagttgg tcgcgactcc gacgtgacgc ttcccatcag ttccaatgcg cggctcgtcg
    11821 aggacagtgt aagtcagaat aacacggttc ttactccaga caggcgatga gccaatgctg
    11881 tactgtctga ctcgcatggg aggaagcata cggaggaacg ccgagattgg gagcttgatg
    11941 tcagggttac tctccagtag atcgagcacg gagagacgac tggcgatgat cgtagatgcg
    12001 tattcctcgt ctgtcgcgag agctgcgagc ttggtcttgg tcttctcgtc tttcgcagca
    12061 tcaatcaaag tctggatgtc acgcttggta gcggcttggg ccagctccac gtaggatccg
    12121 aagatatcca cggcgggcat tgggccgtcg gacgggaggg aggtcactgc cttggacgag
    12181 atggtaaggt gagcatcgcg aggcaggtgg aagtgtcgca taacgcggtg gacctggtcc
    12241 ggagggttga cagggaggac agcgaggtag tcgccagcct tgtaagtcat gtcggagggc
    12301 agttcaatct caatgtgctt cttcttgatc agagcatcct cggaggtaag aacggaggta
    12361 gagacaaccg cagcctcctt gacatcttga cgcagagttg acttgcgagg tgtgctcact
    12421 tccacactga gcgacggtcc ttgaggggct tcagcgccat acttctccat cagggctggc
    12481 cacaggatat tgtcctccca ggcttcaaag tcagtcatct cgttgccttg agcaacatca
    12541 gtcagaccaa gcgctgcgac tctgttgcct ccatgcttgt cgatagtgta atccaccaac
    12601 ttggggatgc ggtggaatgt agcagaccag tcgtggtgac cacaaccaaa gacagcgtag
    12661 ttgacatcct tgagctcctt gctatcctcc ttaaggccct caagccaggg tacaaatttg
    12721 gcagcgttgt ctgggggctg accttcgtag gaagcggtga tgatcaccac cggttcgtcc
    12781 ttgggcaatt gtgcagtggc gttgtcgacg cagtccacag tcgtggcaga gaaaccgtgc
    12841 gaaaaggcgt cagcagccag acgctcggcc atagactgac atgtcccact gttggagccg
    12901 tagaagatct tcatcggctt gccagttcca ccagatactg gtgcagctgt tccatttgcg
    12961 gcagcaccgg acgtcgtctt ggtcgatacc gacataccag caagtctgtt ctgcatctca
    13021 aacgctctca gtccgtcgcg agggatagcc ttgaccttaa agttggctgg cttgacagtc
    13081 aaggtctgct tgagcgtgag ggtatacgaa gggtcgtcga actcgaagtc gaagttttgc
    13141 agaagcatcg caagaacaag gagagcctcc tgccaggcaa atggccggcc aatacatcct
    13201 cttgtgccgt taccgaaggg cttccaggca ttagggaact ccttgttcag cttgttgaag
    13261 ttctcatcca gcatgcgctc tggcttgaag actccgacat ctgcgccaaa aaccttaggg
    13321 tccatttgcg atgcgccaat gagaacaata acaagctcgc cttccttgat cacatactgt
    13381 ccgccgacaa tctcgtcttt cttgggagcg acgttgaaga cggggagcgg tggtgttaga
    13441 cgaagtgtct ctctgaggac ctgtgggctg ttaacacaat gaaactcaga ggccaaggaa
    13501 tattgcatac agctgaaata tatcctagtt tgttcaactg atcaaaccgg atcggcgtct
    13561 ttccacagac gctgtcgact tcctgctggg ccttgcggta gcagtcaggg tccttcatta
    13621 aatggtacaa agcaaacgac agcatgcccg atgtcgtctc gtgtccagca atgagaaatg
    13681 tgatgaggtt atccaggata ctttcttcag tcatcttctt gccagtcttg ggatcgaccc
    13741 cgttcagcat ggctgacagc agatccttgc gcgtatccag attcttctcc ttcttgcgct
    13801 cttgcagaat ctcgtttgca gtgcgtcgca taacttcgat atcaccaaaa aacttcttgt
    13861 ccttcccacg gtagaagaat gaagggatcg gcaaccgtcg tgctcgatca ccactctctg
    13921 tgaggaagtc acccatggct tcaacaaagg ggtggacacc ctccttgtag tagctgttaa
    13981 atcgaaagtc catcgagcac agggcgattg tgtcgagagt cagtcgcgta aagtcgtcgg
    14041 tcactgtaat tgcttcgcct ccgtatcgag cccatttcag ggctagctgg ctggcaatat
    14101 cgtacattcc atcgtacatc atccggagcg acgagggtcc aaaggctggg accaggattc
    14161 tgtgtgcaat tgcccaggcg ggctctgtct ctccatcgat ggccttcgaa agtcagaagt
    14221 ttctttattt ttgattgaag aggtaggctt acagtgaata gtccatcgtg catagcatgt
    14281 ctcatttcct acacaaggtt aaaggtgcca ggcatagggt accaataaac ccaccttgag
    14341 agcaaagatc gtctttggaa acctcttctc atcgcaaaac tcgttgacca tgtcatagct
    14401 gcaggcaatg ataaaggtgt gccccggaaa cttcatgcga tagatctcgc cttggtgggt
    14461 cagcgtgcat tggtgaagct atttggtcct cataccatgt ttagccccta aatcatagag
    14521 cgactgtaag ggcaattcca tatcaatgtc aaatagatta cccaaaaagg gcacgcccgg
    14581 aggctgcggg atattgctga gtttgctcat tcctcctgtt gaatgtaggg ttgagtgtag
    14641 aagtccagcc catgaaccct gagcgaatct gaccacttct tgaacaacat ctcgaagcta
    14701 aagccatcgg gtaattccaa agatcaccgt atgattgggc catgatcatg ggctgactat
    14761 cattaccaaa attgccgact cgagggggcc gcatcggtaa ttatttgggg ctgaacggtc
    14821 gtcagcattg gaactcagcc tgagcctgca ctgccccttg gccccagatc gtttgcttgt
    14881 ccgatgcttg acttgagagc ttcatgaaaa cttagaaaaa aaaaagtaaa taaaaactaa
    14941 tcaccaactc ttgtcgctct tttatgttac atcggtattt gtgcttcctc tctttgattt
    15001 gattgttgtc gccatgctgg ccaaattatt ccttctttcg ctatctcttc tttctcctgc
    15061 gcttggactt gttcctcgcc aggcgccatc gagctcttgc aaggctttcc ctggtgatgc
    15121 tgcatggcca tcggccgggg cttggaatgc cctcaaccgc accgttggtg gtcgtttgat
    15181 cgctacagtt cctctgccca gcgtctgtca tcagactccc tttggcacct tcaatgaaga
    15241 tgcctgcgct gccatgaaga ccgaatggct tgaggacact accttgtaag ttgccagacc
    15301 acaagcttga gtactatctg acatgaccag catcaaccat cctgctgaag tcatgaaccc
    15361 tcctactcag aactactctt gcgtgccttt cacttcttca tcgcaagcat gcaacatggg
    15421 caactatgcc agctactcta tcaatgttac tggcgccgac gacgtgattg ctggaatcaa
    15481 gtttgcgcga gagaacaacg ttcgcttggt catcaagaac actggtcatg agtaagtgcg
    15541 ttcattcctg ccctacttcc tgactaacaa tgacagcttc tctggcaagt cgactggacc
    15601 tggcgctctt tctctttgga cacacaacct gaacacgacc aagatcatcg agaactacga
    15661 gggcgctggc tactctggcc ccgctgctaa actcggcgct ggtgtcatct caggccaagt
    15721 ctatgaagtc gttggtgccg ctggataccg tgtcatgggt ggtacttgcc ctactgttgg
    15781 cctcgctggt ggctatacct ctggtggtgg ccactctctg ctcaacggtg cctatggaat
    15841 ggctgctgat gcagtcctcg aatgggaggt catcaccgcc gatggaaagc acctcactgc
    15901 ctcgcagtct gaaaattccg acctctattg ggctctcagc ggtggtggtg ccggtaccta
    15961 cgctgtcgtc ctcagcatga ctaccaaggt cttcgctgat ggtcccatcg gcagtggtat
    16021 cctgatgttc aacatcactg ccaacgcaac cgaggactac tggggcgcca ttgaggatct
    16081 ctggatgttc ctccccgagt ttgtcgacgc cggccccaac agctgggact ttgccctgac
    16141 tgctgccggt ttccaagcct acgccatcac tgtccccgac aagaacggca ctgaggtcca
    16201 gtctctcctg cagccctggt tgagctctgt ctccaggcgt ggtattcagt actcttttat
    16261 ccccactgac tcagacaact acctcgagta cttctccagc cgcttcggtc caggaattgc
    16321 cggtgctggt cctgcgactg ttcaactcac ctcccgtctc atcccccgtg ccgccatgta
    16381 caacaagacc gagacaaagg tcatcgtcga tgccctccgc caagtcgtcg agctcgaccc
    16441 cgaagcctcc ctcggctgcc acgccctgaa cgtcgcaaac gtcgaacacc ccgacaacgc
    16501 cgtccttccc gcctggcgcg aagccatcgc aacctgcaac atcgtcacct actgggactg
    16561 ggacatcagc gaggccgaga tgtgggagaa gaaggacctg ctcgtggaca ctctcatccc
    16621 cggccttgaa gaggccaccc ccggttctgg aacttacctc aatgagattg acgccggctg
    16681 gaagggagac tggatcactg agctctatgg cgagaactac gatcgtctgc tgagtatcaa
    16741 gaacaagtat gacccgcagc acgtcttcta tgctcgcact gctattggta gtgcttcttg
    16801 gactagcgat gccactggtc gtctttgcag ggtttaggaa gtctttcctg agagattcat
    16861 tgcttgtata gatagagtat agctattttc gcttcgacaa cttcttttct agaacatact
    16921 tcaatgcata ctttgcttat tataatatat cctcaacctg taacctggat attacatttc
    16981 atgaaacccg caatatcttt gtttactcag atcaccgagc tagcagtcat aatttaacaa
    17041 aggctatata ctccgtactg gttaatcatc gcgcattcga caatagagaa tgcatattca
    17101 agaaccaacc taaattgtgt tgaactaaca gcacataaca ttccagcaaa atccaaacgt
    17161 ccgtcccagc atttcaaaca ctccagccca tcctctacaa ctcaacatca ggcacgcgac
    17221 tacgcacctt aaccttaaca gtcggatccg aatccaacat aataccatgc gaaatagcct
    17281 tgggcatcgt aatcgagctc agttcccaat catgcttgag caacagatgg caaagggcaa
    17341 tcttaacctc gttagcagcc aggaagcgtc cagggcaggc gtgctggccg tgaccaaagg
    17401 cgatttgttc ggggcgcgta gtcgtaagtt gccagacgtt ctcctggcca ggctgctcgc
    17461 gcagacggac gaagcggaag gggtcgaatt tctcggggtt ggggaagatc ttggggtccc
    17521 aggaggcgtg gctggagacg ccgagacgtg tgcccatggg gatatggaag ccgtcgggaa
    17581 ggtcgatgtc ttcggttgcg gtgcggacca tgttgactga gccaattagt ttcgattcca
    17641 tatcttaggg aaggtggtta gacttactcg acaagacagg cttcaatcgc tgcgcctcct
    17701 taatcacact gtccatgagc ttgagattgt agagagaaga gtgcttcagc ttcccatcac
    17761 caacaacagc cttaacctcg tccctcagca actgaatagt ctcaggatgc tgcaaaatct
    17821 catacatggt cgtcgtgagc aaatcagtag tggtatgaat cgccgaaagc gcaagagtaa
    17881 gctgcatagc aggaggcgag tacttgatcc ccttctcctg cgcaacctgc tcaagccact
    17941 caatcgagtc attgcgatcc ttgtacgcct cagggttggc agccttctcg gcacgacgac
    18001 gctcaatgat cggttcaata atggactcgg cttcgcggag ttgaccgagg actttacgcg
    18061 cttgagggag gaactttgcg acgaaggaac ggagaaaggc tgggtaggga cggagctggt
    18121 ggaaggcgat gaaggagtcg acggtgtatt cctttgtgat tttgagccac gctgggtctt
    18181 gcgagacttc ttcgtcgccg aggaagatga cggaggagag gcgggcgacg aggtcgagga
    18241 gttcgtcttt tagggttact tctttccagt ctaatcattt tcataagtta gtatctatgc
    18301 ttggctaggt acgtggtttg gtgtggttga cttaccgttc tctgaagtga agaggtcttt
    18361 gcaggcgttt gcgcaggtct tggacagggg atatgtcagg ggttctaaag tgatcagtaa
    18421 cttcttccta gcggttatca tccgggaaac atactcatag cgctaatcag cttcgtcttt
    18481 gtcatgtcaa tcaggagagt ggttccggtg gactcgaggt agggctcgaa accagggact
    18541 tcggcgcatg ttgtctgcaa cgttagctgg atttcgaggt cagtctgagt taagattttc
    18601 ctacctcttt cataaagacg gcgtgactca gcgcgtcaat gttacggatg tcgtgcgcca
    18661 tagccggggg taagatgagc atctctcctt ggtcggagat gatacggtag ggcttcaaga
    18721 agccaacctt ctcgaaaccc tggcgaataa cggcacgcgc attggcagtg aagttatcct
    18781 ttgctttctt gccggtgata tcccaccagg ctttttctgt gacgagggga acatttgcga
    18841 gcgggttctc cttgagcagt gtagagacaa tcaccgcaat taggccggta acgagaacga
    18901 taatggagat gtacggacgg gtttcaggag cagtgtcgaa gctgtccgtc gtagtgatgt
    18961 tgtcaagctg cagatccatg atgttgttac tgcagttgat gcaaaacagt atggcgcagg
    19021 aagtttcaag cagagcagag agcagaagaa ctacaacagc ctacgatgtg cactgttttt
    19081 tagttcaacg tccggctgaa tagcacaact gccgacagta agtctatcca ataggatgca
    19141 gcggaaaggc ccaatcgacc caagccgtcg gaagttttga cagggtcttg gtactcgtac
    19201 aatcaggttg gcgatattgt caatggggat agggctcact agatggctgt gggtctggag
    19261 cacagctgat cggcagtttt gtacagcccc gggaactgtc tagactcgct agtaaataac
    19321 tgaagataga tatcggctgt cagacggccc ccataaatat tcccgagtac tgttcactgt
    19381 caaaattccc gaattgcggt gggggctgta gttgaggctg tccgatcggc agtctgctta
    19441 ccatgctgga ctatagacta tagacctgtc gcatgtcaag atcttggtat cctgtacttc
    19501 cttacgataa tctcagttct cctcccacta gcaacttcaa cagtacagca caatgggtct
    19561 cttcagcagc gaaaagccgg tgcagcagcc acccaaggtc ccgacggacg aggtgattcc
    19621 gttgaatgct gccgacgaca ccgatgtgct tcgcagtgtc tgcgtggttc tgtcgtatcg
    19681 cttcgatgat gtgcttgatc cggagaagct gaagagctcc tacgagaagc tgctggaccg
    19741 accaggctgg cgcaagattg gcgcgcgttt gcgactcaat gtacgttcaa ataaccaaat
    19801 gtcgcgaatg gtctctaaca gaggttcgtg cagcccaatg gacgactgga atatcacatc
    19861 cccgagaagt acgatgagac gcgaccaatt gtgacctggt cacatgtcac gcacgacatg
    19921 tccatcaccg aacaccctct ggcctcgaaa ctgccccgac caacaacaaa acctgcagtt
    19981 gtcggtgatc cgcacgattt cgacgagttg acgtgcagtc ccgacgctcc caagacgctg
    20041 gacgactacc tctcccgaga tgttcctcaa acatgtctgc acgttgtttc cttcaacgac
    20101 tcaaccctga tctccatctc tctgccgcac actctcacag acggaacagg cggtgcccaa
    20161 atctaccgct gctgggcgct cgtgctgcaa ggccgcgaag acgaggtccc cgacttccac
    20221 ggctacgaca gcgaccccct agccaccttt ggcgacaaat ccagcgagga gtacatgttc
    20281 gccccccagc tgctaaccgg ctggagaaaa tggctgttca ttgcgtacca gatctatgat
    20341 ggctggcggt acaagacgtc gtcgcgcatc atgtgcgttc ccgggcccta catggctgcg
    20401 caacgcaaga aggccattga agagattcgc gcagataccg gcaacgacaa ggcctttgtc
    20461 tccgacaacg atgtgctcac agcctggttc acacgtctgg aagccggcca cttccccaag
    20521 aactcgaacc tcaccgttcg catcatgaac gcgttcgcct tggctgctgt gctgggcaac
    20581 gaccacctcc ccacaaccaa agtgttcatc tccaatgccg ccacagagat ctataccttc
    20641 ttcacggtgc gcgaactctt caccaagccc cttagtcagc ttgcctggaa aatccggcaa
    20701 agcatgatga ccggcggcac gcgtgagcaa gtcgaggcct tgcaagccgt caagaagcaa
    20761 accctagctc gggagggaca cacctggccg atgttcggcg acgcatcaat ggagatgatg
    20821 agctactcga actggacgaa aggaaagtac ttcgagacag acttttcagc ggccatgacg
    20881 cgcgtggggt tccctgagaa ccgccgtgct gagaagccag ggtacgcatc gatggtacag
    20941 ttcaatgcgt ggtcgaccaa gtttgacctg aggaatctga tgcccatcat gggtaaagac
    21001 gcggcaggaa attattggct gcaggggccg ttgagagacg ttgtttggag gaggattgag
    21061 agggagttga aggcggcaaa ggattagaga tagatttcat tgtttgttag gagtaattgg
    21121 ttggcttgtt gataatgtta ggttgaataa tagatgttct gtgcaagttg tgtctagtgt
    21181 tggtagcgcg tagcagagga gacgacggaa gacagtgtag ctgacaggag caagactgca
    21241 aacctactgt gtgcgggatg caaatttggg ttatagtacg tcaaaatgtt gcatctatca
    21301 catgattagg caaggtggcc gagcggtcta aggcgcgcgg ttaaggtaca ccaataggcg
    21361 aacctcctct tgtaatcaca agtttccgcg tcattaattt ggcgtgggtt cgaatcccac
    21421 ccttgtcata tctttttgct gtttttgttg atggaatatc atattgtttt tatggtgctt
    21481 atgccatagt agatggtatt tttctgcttt ttataagcag tgttataatt aagagagttg
    21541 gaagtatcta ttttgtccag atgaaatccc ttggtgctgt ggtgatcgtt ttccaagaag
    21601 tcttcggctt gtcgcgaaaa tatatataac ctccactacg acaccgcacg atcttttact
    21661 gaagatacga ctgacgaaga aatctacgaa acaagaagac tgcaaataaa ccaaatcatt
    21721 aattaaccca actcctatat tatatacaat gctctattga gcagccttca acatgcgagg
    21781 gtagtgaggc tggccagggt cgtccatcga gtcaatgagc gcagcaacac cgcggttcaa
    21841 tcccgcctcg actgcctttt gcgaccacaa ttccactggc aactcctgca cattcacagc
    21901 tccagtgtcc ttggccacaa actccttcag gtcctccaat ggagcaacaa tatctccaac
    21961 ttggtgagtg taaacaactc cctgctgctt gttgctaaac accgtcgaca gaatactgtc
    22021 cgtcgcgttc ttgacataaa caaagtccag cgcaccccgc aggttcttca acacaggcac
    22081 cgcacgcgtc ttcctcatgt actcgacaag cgcattcatc cagtcgattt gcgcagccgc
    22141 gttcgtcgcg tcagatccct cacggatgat cgtcgatgga cgatgaatcc agacgttgag
    22201 acccgcttcc ttcttcacct cctccaacaa ccgctcactc gcccacttgg ctgcgacgta
    22261 tccgtgcgat ccatcgacgg gaggctgatg ctccgcgact gatacctcag ggaaagactt
    22321 gtagttgcca aagagggcaa ctccgaccgt cgaaaggtag tgtatgggca ccttgcggga
    22381 gatacaaagc gagatgagtt ccttggtcga tccggtgttg gcggccttga tctcggggta
    22441 aaacttgaga tgcgaggtgt cagcgccatt gtggatcacg acatctgctt ggctgaagat
    22501 ctcggtcgcg tccctctcgg agaggccgag gcggggggtc tcgaggtcac cggcgaagta
    22561 ctggacacgg gcatccttgg gaagttcgtt gatgcgctcg ttgaggcgac ggacggcgat
    22621 acagaagacc ttcttgacgg aagagtcggc gagcaggctg ttgaggaggt tgcgaccgag
    22681 cagaccgctg acaccggtga gaacaacgtt ctggggacga gcagcgggcg cgcgctcagt
    22741 ggaaatctta gcagcctggg gaagaacaat ctccttcgac cagtcgatgc gcagaggacc
    22801 cttcaccatc tgaggaggct ccatggtgac tggcgtcgtg cgaccggtcg atccgccgtg
    22861 aacggactca gcaggggtac catcgttgga gtcagaggag gaggcggcat catcagcagc
    22921 cttgacaaca acggtaggag tcacagagac ggcaggagta tcctcgaccg ggacaggggc
    22981 ttcaccgtca ccaccgagac cagggagaag ggactcgggg cactggtcgg cgacaaggtc
    23041 ggccagctcg gccatagtgt cgttacccat gatcttgagg acggggacgc tgacctcgaa
    23101 attcttgagg aaccaagaac ggatgtcgac tgagatgagc gagtcaagac caatgtcacg
    23161 gctgcggaga gccatgaggt cctcgtcggc ggtggtcatc tggaggacgt tgcggagttg
    23221 catggcgaag cgagctgttc gtgtcagtct ggaaccatgc gaaagagtgt gaataactta
    23281 cccttgacaa cagcaaggac atcagtgcgg gacttgcaag cagcgagctg gtcttgaaca
    23341 gaggcaatga cctcgtttcc agcgtcggcg ccgttcttct cgacctggtg aacgataaag
    23401 tcgaggaagg ccgggttaga gtgccacttg ggcgtgttct cgtcgtcctc ggcagcagga
    23461 atatccagta gaccagtggt gagttcggcc tcatccacag agtcaggacg acctgcgtca
    23521 ataccctcag cgaacagctg gtggtagtcc tgctcggaaa gatgcatgag agccatcttg
    23581 gagacagtca ggtcaagagc cttgctggac tcacgctcca tgtaaccagc accgataatg
    23641 gcaccgacgt tgagagcagt agcagccaga ccacgcttgc gacgctgagc agcaagactg
    23701 cacatgaagg tgttggcagc agcgtagttg gcctgtccca ggtttccaat aacacagtta
    23761 atggaggaga acaggatgaa gaagtccaga ggagtatcct tgaagatgcg gtcgaggtga
    23821 atagaaccgt acaccttggg acggaagaca tcgctcatga gctcaaagga catgttggca
    23881 atcgagacat cacggagaac catggcaccg ttgaggacac cagcgatagg aggctgggtc
    23941 tcgacgatga acttgtgggc agcacggagg gcaggctcgt tggtaacgtc gcaagggacg
    24001 atcgtgacat tgacgccgtt cttcttgtgc gcggcgatcc agtcaggcga gatgttgggg
    24061 ttacgactgg tcaggacgag gcacttggca ccgcgctcga tcatccagtc aaccagcgag
    24121 acaccaaggg caccggagag accgcacagc cagtaggtct tgtcgccctt gaagaaggca
    24181 ccggagtcga gacggctgac gtggacgggg tgagtcttgg agagagtcca gtcgatgacg
    24241 gtcgcggggt cttcggggtt ggagccctcg agaaggtcgg cgatgctgac tgtctgagga
    24301 gcgatagcgt ccttcttgtg agcaagagtc tcctgctgag cgtagaacca agcgcgctgg
    24361 agaagctggc cgagggcaga ggccgcggag acggagacgc tctcccagcc gatgggagag
    24421 taaagagtgg agacattctc cttgcggcag tggatgggaa gaccagcgat aatggacgag
    24481 gcgttctcgg aaccctggac agagaagtca acgaagcagg cagtgttggc agggaggata
    24541 tccgcaatct cggactgggt catgtaaggc tccaacttgg cccaggcctc aggagcatcg
    24601 gcattgctgg agtcggcgac aaagacggca tggaccttct tgctggcagc gtgagtcgag
    24661 atggtgttgg caaggagctc ggttgcgttg tgcacaacca gagtgtcgcc atcaacaagg
    24721 gggtcgacga cagccatgga aatgaggcaa gcagcaagag aagcctggag ctcagcatcg
    24781 gtagcagcgg ccttgggaac agggacagcg gactccttgg cgatagtcac gacagacagg
    24841 aggctgggaa caagagccat gaagcgacct tgagtcttgg agtccgttcc aaagaccagg
    24901 aactggtgac cgtacgaggt gcggacggca gagagcacag cgtggctgac ttcaagagtg
    24961 atggtctcgg gagtctcggc gggaatagcc cagggggaca actccttcag cttccagccc
    25021 tcaccatcgt tgaataaggc ggcaggagac ttggtgatgt cggtctcgtt ggtgatgggg
    25081 cggcgagcag agttgtaacg gtcgttacgg gcattgatgt ggcggagacg agggacaagc
    25141 tcttcaccat cctccttgac gaggatctca ggctcaaggg gccaagcgag ctgcttgacg
    25201 tccggaggca gagtgctggc cgaagcatgg aagcggagga ccttctcgac gagatcctga
    25261 gccttgacgg tggaaaggtc agtgaagtcg acattctgga agcgcagggc gggagtctca
    25321 aagaccgcag tacgagcgaa accaacagtc atgttggaga agggaacctc ggacagtctg
    25381 ccgctggtga cccagaagag cttggtaggg catgagaaga gagtcttgaa agcagcccac
    25441 tcttcgggag tcaagtcctc gaagacaggc ttgtccagct cagacaagct gaccacaatc
    25501 gcattcgcgt caacaaggct gaagtcgacg ccagttaggg tctcgaaggt gtagaggttg
    25561 acagcgctct tcttgagggt ctcagtgatg gacgagacaa gggagcgagt cttgtcagtg
    25621 ctgcctccga tgacgacgag cttctcgatg gggtactcga tggcagcagc gctcttggcc
    25681 acgacttcag ggttggtagg ctcgcggatg aagttgacgc ggtcatcgac agcctgagca
    25741 gcaaagacag tcataccaag gacatcctgg aaggcctgag gagcggtgga atcaatgcca
    25801 gagaatccgc tgccccggag gagtctctcc cactccgaat aagagacgaa aggagacaga
    25861 ggacgaccag agtcagcacc aagccaccaa ccaggcagag agccaaagat gaaaccggcg
    25921 cttccgtagg gctggccgtt gttggtaccc tcaccgacaa tcaagaaacc accaggcttt
    25981 agcagcttgc ggatgttgcg catcgtcagg tcaaggtcag gggtcgcgtg aatgaccaag
    26041 aaagcaacga tgacatcgta agttccctcg gcgtaccctt gagcaacagg atcctggcca
    26101 cagtcgaaag tcttgaagac catgcggtcc ttctgctcag agaacatctc ggccgcaccc
    26161 tcgaagaaac cactcgagac atcagtaaag gtgtaagaga ggaacttgtt gttcagaccc
    26221 tgcaggacac gagtcgtagc accaccggta ccagcaccga cctcaaggat gttcaggtga
    26281 gggtaacgct ccgcaagctg ggagatgatc ttgccaatcc agagaccagc ctcgcgggat
    26341 ccaaaggcgc ccttgtagta gttgtccagg atgttggaga cacgcatctc ctcgagcatg
    26401 ttggtctcgc cacggaggac acggggcatc tgctgtccaa cgagatgcat catgtcgtag
    26461 tcgatcaagt ccttgaggtg accagtcttg cggtgcaggt cctcaaggga atcactgagc
    26521 cagtcgtgct tagcaacctt gtgctcgccg ttctggatga gctcgacaat gtggtgggcg
    26581 tagttgaggt aatgcatgtg aggaccctcc ttgcgaagag gcgagtccat aggaacctca
    26641 gcatcaagct tgttaaggta aaaggtcgag atgcgctcga gaccctcaag gacatcctcg
    26701 tggtgcttgg tgacgttggt gtcgtcagca gcgaggtcac cgtccagacg gttcttcacc
    26761 cactcgtact tggagaagac cttgcggtca tccttggccg tgagagcacc aaggggcttc
    26821 agctcaagac cctgtatctg gatagcggcg caggcagagt cgttggtgaa caggctgacg
    26881 tctccgttga agccagcaga gcgcctggta ccaagtctgc cgtcagtggt gatatcagtc
    26941 atggactggc acagggtagg gttgacacga atgctcttca tgctagtagg caagtgcatg
    27001 ttcagcagct ggtcatcatc agggtaactg taagccagga taagcgattg aataccaccg
    27061 tcaagctcag cagggtggac aagcagaggc tggccaaaga caccctcgcg cgagatcgag
    27121 tggacagagc aagagctgga tccaagcttt ctgcgcagag tgtgcagcga cttgaaggga
    27181 ccctcgaatc cgtagccaag cgtagcaagg aaggtgtaga agcgctcgtt gtcgacggag
    27241 atcatatgag gctgcttgga ggcgcgcttg gggagagtcg cctcagaggc agggccaaag
    27301 acaatgtgca gttcaccctc agcgacaagg tcaagatcct cctcgccaat ggaggcagag
    27361 taagtgaact tggcgacaag gcggtccttg ctgacgttct ggatgtcaga gagtgaagac
    27421 tgaacctcaa taccagcgtc gtcagaggca aaggtcaaag cctggtgaat gacaaagtcc
    27481 ttgagctcga agaggcgcac gtcacggtcg ccagcaagga cacgggcacc ctcaaaggca
    27541 gtacagatgt atccggcagc agggaagaca gtctggctct ggacctggtg accagaagcc
    27601 cactcgatct cgctggcacg gagcaagtta ccccagctga ggtggtgggc agcgctgtcg
    27661 ggcatcatgg taccgaggag cgagttgaag ggctgagtct gggccttgtg cttcttggag
    27721 gctcggggct catgccagta ggagccctcg tggttccact ggtaacgggg gagacccttg
    27781 aggacctgaa gggcagactt gttgtcgttg acttccttct cgaagttggt caggtcaagc
    27841 tgctcgcctc caacgcgggt ccagagcgat ccaaggctcg tggcaaaggc aacagtagca
    27901 tcagagccac ggttgagaac accaaagtag gggatcgcct tgccgagctc ctggatggtc
    27961 tggctggcag ggcccttgag ggcagggtga ggaccaacct caagagcagc ttggtactcg
    28021 ccaccctcaa ggatgatctt gagagcaggg tagaacgaga cgccgcgagc aacactggca
    28081 ccccagtact catcgctcaa tcccatgtcg gaagtgacct cgcggccgta gacagacgaa
    28141 atccagagag gagcaccctc accaggctca agagccttga caccagcgcg acgaacaagc
    28201 tcaacatagt cagcgaggtg cttagagacg tggttagagt ggtaagcacg gtcaacacga
    28261 agcttgcggt tgaacttgtt ctcgtcatca agaatcatct tgaactcgtc aatggcgtcc
    28321 tcgtcaccgg agatggtaac ggaggaggaa gagttgatag cagcaacgca aagacgacca
    28381 gcgaacatct cgtcctcgca gagggctact gcatcttcct cagacatacc agccgcaagc
    28441 atagcaccag tcttgtcggc gccatttgga gagaccatct tggaggcaaa gcgaccacgg
    28501 aagtaagcga cacacatggc atcacgggcg ctcagacgac cagcagcata cgcagcagcc
    28561 atttcaccag aggagtgagc gacgattgca tcgaactcga caccagcgag cttgagcagg
    28621 tcaacgagga taagctggac aacagtagag aggaacgaga aggcaccagt gagaacgcgc
    28681 gagtcctcct tagcacggcg aagctcctcc tcaagggaga agtcgggacg gaggtcctcg
    28741 gggagctgct cgaggtgagt ctgaagctcg gcaatcatct tgcgagcagt agcagactgc
    28801 tcgagcagct cagcacccat gcgagcgtac tgggcaccct gaccagtgaa gacaccgatg
    28861 atcttgcggc gcttgtcgtt ggtagaggcc aggcgaacac ccagctcctc ggtcttggta
    28921 ccctcgatct cagcgcggat cttagaaacg aggtcatccg cactctgagc agcgaaagag
    28981 acacggtagg ggaaggcagt gcggcgagcc tgtagagtgt aagcaaggtc gcggaggctg
    29041 atagcagggt tcgcctcgat gtagtcggcg taggcagcga gagtctcctt gagcgatcca
    29101 cgagaaagtg cagagaagac aaaaggagtg aattgagcag aggagtccgc accgccattt
    29161 tccaggcgag caggctcgta gctctcgaga atcgcgtgcg cgttggtacc accgaaaccg
    29221 aaggagttca cactggcacg acggggctgg ccggattcaa ccgacggcca ggccttgggc
    29281 gccttgagga tctccaagtt tttggtgaag ggagcaacag tctcactcag ggtgttgagg
    29341 agcatgttgg gtggaacagt gctgttctgc agggcgagcg acgccttcaa cagagccgca
    29401 acaccagccg taccctcagt gtgtccgaga atggtcttga tcgaaccgac gtaaagcggc
    29461 tcctcagcaa ccttggtgcc atactgctca ccgaagaaag ccttggagat ggcctccgcc
    29521 tcgatgggat cacccgcagg cgtaccggta ccgtgggcct cgaagaactg aggacggtcg
    29581 atagccttgg acaggtcaag gccggccttc tcatatgtgg cttcgatgag ggcacgctgg
    29641 gcggtggcgc tgggcatggt gataccggtt gtagcaccgt cctggttcac gccggtctcg
    29701 cggatgatac attcgatgtg gtcgccgtct tcgatggcag cgctcaatgt cttgagaata
    29761 caggctgcga caccgtcacc tcgcgcgtat ccgttggcgt ccttgtccca catcttactg
    29821 cggcctatac agcaaatata ggtcagtcac cattgataga gggtatcaga gacacaaggc
    29881 aaggcttacc atcaggagac aacatcttca gcttgctttc cataatgtaa ttctcaggac
    29941 ccaacaacaa gttggatccg caagccaaag cgacgcgcga ttcaccattt cgcagtgcct
    30001 gcgctgcaag gtgaacggca acgagagagg aggaacaggc agtgtcgatg gtcatggaag
    30061 gtccatgcca gttgaagaag taggacacac ggttggacag gatagaccgt ccaataccgg
    30121 tggccgtgta gacgggggcg gtttttacta gaagagttaa gtactttatc agggggaagg
    30181 gcagaggtga ggagcataca gtcgcgaagc acactggcct cgtagtcacc gcacatcaaa
    30241 ccaacataga cggcggtatc acttcccttc agagaatcaa tagtcagacc cgcagactca
    30301 agaccctcat agacggtctc catgagtaac cgctgctggg gatcaatggc ctttgcctcc
    30361 acaggcttga taccaaagaa ctcggtgtca aacgccgcga catcctcctc gagcaggtag
    30421 gagtgctgga tgttgctgtg cccgtggaag gcagagttag gatggtagta gttatccttg
    30481 ttgaacctgc tcgtggggat atcgctgcgg acatcgcgag ggttgttgag caactcccac
    30541 agcttcgagg gggacgaggc tcctccggca aagcgacagg cgctgccgac aatggcaatg
    30601 ggctcgttga tcttggacat ggtggattag aggtaagaag gtaaagaagg agatgattgt
    30661 cttgtggtat agttgaaaag actgaatata agatagagca ggagtcacgg gtgttgaacg
    30721 tgtagggctg gctgggctgt cctttctatc aatcgagcag caacaccctc tttaaagagg
    30781 acatctcagt tcaatctatc ggccagcccc aagactcagc catactacta catccagccc
    30841 tgtatcacgt ccatagcacc tgctgcagta ttactccggc atgggggcca aacaacaagc
    30901 atcgatagcg aaattgccta tacagagaac ggccttcagg atcccgtggc gaaggcgagt
    30961 cctccacctg tccatgaacc aatcactgac caacgccaga ctagccggac gattgacagg
    31021 gagattgacc gaattcgcga aagcgttcgg ccatttcgcc cacagcctcc ggggggagta
    31081 tgggatatgc tccgagcgct cgggaataca cagtgcagct cagttggggt ccaggaatcc
    31141 tgcaggcaga tcgagcttgt gcagattacg accttagctt gagctctaac tagtaactcc
    31201 aagacatccc agctgccacg cggctggtat ctcgtctgtc gtctgttcgg tggagtggtc
    31261 tatagtggtg gagccctatt acccgactct tgtggacctt gcctgcctca gcttcagccg
    31321 ctactccata cgctgcacgg ccgtactgta ctgtactctg tacgtgttcc tacactctag
    31381 aaatagggac tatgttccag ccagacagac ggcgatcgcc attcagcttg gtggagtgta
    31441 gcttatacga ggcggcccct gtcactgcca ctggcgctaa cccccatctc aaccgttgtt
    31501 atcgccgact aagctcgatc taaggatcgc catgttcttg gtcttttctt gggtcggccg
    31561 aagtatctgc atgtggctta tggttgttct tgggtgatcg gtgtagaagt ggcctgaggc
    31621 ttcgatgtcg ttgctgggtt ttgctttctt tagaatatct ttaaaatgta gaataaccca
    31681 aacaatactt tgtagaaatg tatatcgaca tacatacatc tagataatta tgtcttgatt
    31741 catggatcaa caggtgatgg gccaaactgg aagcgttgtt ggggatttag ccgcgtggtc
    31801 aaaatatata taactttgtc gcttcaagta cactggcatt tcgcatagca acactacgat
    31861 caagcaatac aaaaaccagt cattatgcgt atgaggatat atttacataa atctgtatgt
    31921 atatggaaag ttccaaatga agagtcaaga ttttcccctt tagataaatt ttattcatca
    31981 acgccttcaa caccaatcta tctcaaacta tccaaaacgc tcaaaatata gaagctcaac
    32041 aattagacaa atactacttc tgctctctca ctcatttatc ctcctcctca gcagcaggct
    32101 tcttgttctt tctgatatcc acccagccca taccaaacgc agcaacaaat cccagcagac
    32161 acaaagccat tagcaggtaa aaaaccttgt caacactgtt cgagaaggcc atcaagacgc
    32221 cagccagctc agggctaccc tcaggaacaa gcgtgcgcac agagtcggca ctcgcaccag
    32281 cagcctcagc agcttcgacg gagacagagg gagcgtactt gacaatctcc ttgaccaatt
    32341 cctgtgtaaa gatgacctcg ccgaccacga cgaagaccgc accagcaaag ttctgacaga
    32401 agatcatgaa cgcgattccg acggggattt tctcgggggg gaggaggttc tggatggcga
    32461 taatccccta gaaaccatca gttaagaaca ataaaaagag agcattggac caaccatctg
    32521 cattccaata ccgcgaccac ttcccaaaac gatctgatac ccaatccact tatccgtagg
    32581 cgtatccggc ctgaacagcg taacaagccc attaccaacc gcactgatgg cactccccgc
    32641 cgcagcaaaa ggaagataat agccaacttt ctgtacaaca ccaccagaaa taataacagt
    32701 gagcaactgg ctaagaatac cagggagggt attaacacca ctcatcgcag ccccataccc
    32761 acgaacaccc tggaagtaaa taggcagata ctgcgaagcc gtgagaatcg aagcgacgag
    32821 tgttccgccg ttaatagcac tcgtccagac aatatggtgg ctgaccatcg acgtagggat
    32881 catagcacga tcacccatct tccattccca gattccaaag actgtgattg ttgctgcggc
    32941 gccgacaaac aatccaataa caacggaact atcccacgcg tactcgttgc caccgtagta
    33001 tagacccagc agcgccatga tggccgccgg cgcaaagagc gtaaacccga tgagatcgag
    33061 atccggaagt gtcttcttga cgagcgcaag cgagaacggt tccttcttag tgagttcagg
    33121 cacacgcagg aagaggagga gaactgcgac gacggcgccg acgggcaggt tgatgtagaa
    33181 acaccagcgc caggttgtgt actgggtcaa ggcacctccg atgaggggac cgcagacgat
    33241 gccgagttgg gagactatcc tcgttagcga gacaactgaa agtagggttt tagcgcgtgc
    33301 atacttccaa ggtagacacc ggtatagaca ggtcgctttt ccaggggcac tgcgcccgcg
    33361 atgattgtca ttccgccatt gaggagtcct gaactgccga tgcctgcgac ggctctgcct
    33421 ccgattaggg tggatgagga gttggcgaca ccgcagatga gcgatccgac ttcgaagagg
    33481 aagaagaaga agaggtatgt ccactttcat actttgttag ctccctcact tagtgatggg
    33541 tgggcgacga accttggtgt tgtaggaggt gtatatcttg ccggagaggg gctggagggc
    33601 agcactaggc gacgatgagc ttcgtagtag tttgggatag atgaagagac ttacctagat
    33661 agctgatacg cagcggtata ccatccgaca tcatgaatcg agtgaaactg actggtgatg
    33721 ttggggatag cctgcaacgg tgagttcaac ccacaacgcg gagagatggt aagcaaccta
    33781 ccacaccaat aatagaccca tccagcaaca tcaaaaacgc agacaaggta acactggcca
    33841 gaatgccaaa cagcttgaaa ccagtgacac caggagcctg gaccgccgca gcctcagcag
    33901 gaggatccgc cgccgagctc tcctcatctc cgggcttctc aatcactctc gctgtactgc
    33961 catgctcctg ctgcgtccag ggggcgcggg aggactcctc tgtgttttgc gttctggcgt
    34021 ccgactcgcg cgtgttggga cggctccagg tctgcagcgc gacaggctcg tcgttcatct
    34081 tgacagcgat agcagtgaga caagatacgt acagctacga tgacaaacga ggaggaggcg
    34141 aacagccggc agggggcgat tgaaaagggc ttgtttcgac agcagtaaca aagggccctc
    34201 cagcagagtt tgcgtcagag gagaaaccaa agtgactgag tgagggctcc ccagccaatc
    34261 tgccttcacg cacacagcca gggtaacgcc gaacacaata gcccccagcc cttagccagt
    34321 cagtcagcac tacgccctaa caagcaaaag cactccatta tcgatctgca catcgcacca
    34381 aacgcagtat agcgccttag ggagggaccg aaattcccga taagcctggc caatcggtca
    34441 ttcttgactg gcgatcgctg gctccacggg gcatcctttg acaagccagt ctgaccagta
    34501 agctagcatt gcgagctaag gaagtgtctc tttggtcctt gggggccctg acatctttga
    34561 gcttggctgt gcatggctga tccacagcac gaagcttggt tgttgagtct gagtcccttt
    34621 gttgctagta tcgtcaagtg cttagcgctg cagctgaaac tagcggtgca gccttttttg
    34681 gggccgaact gccattcgga cactgtccga gaatttaccg agtagaggtt gtagttacac
    34741 aattatagag ttcttagatt caaaaaagca atttgaggtc acgatggttg ttgggtaggt
    34801 gggagttgag gggaggaaga ggaggaagaa gaagtggaag agaattaggg ttgagttgaa
    34861 tgctatttga tgttcattgt ctatactaaa ttcttgatcg tcaaacatta taggaacata
    34921 ggaaaatcgt catcattcga gcccttgaat caggcgtatc ttctccttca gcgattcgat
    34981 cacccccaag ccaccgcgat cctctgtcgc cctctcagtc tcgacttgca tcagagtgga
    35041 gaagagcaat tggccactct gcccgctgaa cagcccagtc tgcttatctt tgcttgcgga
    35101 attgcgtttt agcgacacgc agcattcgtc gggaaggcct aacagcatct cgattggccg
    35161 aagttggctc gccgtgatgc agtagagcag gtggctcaaa agctccaatc gaggaggaac
    35221 cgcgataccg ccgaggtaga gctttggcgc agactgcaag acgatattca ctgcgccggg
    35281 attatgggat gcttgttcgg taaaatggga gaagatggaa tcataaatgg aaatcgtcaa
    35341 catatgacag gacaagatgg tgaggaggtc cggcatgctg aggcgcggat gaatagaaga
    35401 caacggactc gaagccttgg acgtattgct ccctccatcg ccagcgatag gagattgcac
    35461 agagcagaga agctgcgcaa actcggcaga cgttttggcg atctttgcca gcgggttcga
    35521 cttcagatca tcctggctgg gactggaggg ggccgaggta ccaggagctt ggaagcaagt
    35581 caattgcata accttggtca tgtcccaagg catggacgtg agagtgtata actgtttgga
    35641 aagttcgcgt tgtaattggg aaaggtgaag gccgtgatcg aagtttgccg caaaaggttg
    35701 aggacccggt agcggcagct ggtcacacgg gtcatcttga aagtggtcgt ggataggggt
    35761 atgcgttggc atggtagtga ggaaagcagg agtggaagcc gtttgcaggg gaggcgtgga
    35821 tagtgaagac atcgatgtgg cgacgccttc catggggaac cctgattcga agcccgaatc
    35881 aactgaggtc cagggagcag agcagatctc atagtctgta tccaaggaac caaagttgaa
    35941 ccagtcgtcg acattctcga gggattgagg aggtatatcg atggcgggca aggcagggtt
    36001 tgtttcgatg ccggtattcg gactcggcgt cggttgttgt tgacgggggg tattggtcga
    36061 attcctggga cgaccaggac gtttagacga actggtaatg cattccatct gcgagcgcac
    36121 gcagcggata cagtgatcat tcggatggcc ggagacacgc agacatcgga gcttctgcgt
    36181 acggcagcga tcgcaagcag cgcgcttctt gggaggttgt tgggcttgtg tttgttgatc
    36241 ggacatgttg aatgacccta aagtgagcaa tcagacaact cgtgtgcagt ggacgtagct
    36301 gcagctgcag aagggcaaag gaagcaggaa cagcggctat taaaggcatt ggggctgtag
    36361 ctagctatga attcatttta tctcctttct ataaccaacg cagacgccga ctatagtggc
    36421 ttgtactcta gagtatggcc cccaggaata ttctaccgaa gcagagccat ctcgtctcgt
    36481 ccatctacat ccagcttgag
//
