BGC0002170 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002170 (Aspergillus stellatus (Emericella variecolor))

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	36,500	4-methyl-5-dimethyltetradecahexaene-β-ketolactone/4-methyl-5-methylheptatriene-β-ketolactone	PKS	100%

BGC0002170 - Region 1 - T1PKS

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Location: 1 - 36,500 nt. (total: 36,500 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 36,501
Label		BGC0002170

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002170	1.00	Polyketide	4-methyl-5-dimethyltetradecahexaene-β-ketolactone, 4-methyl-5-methylheptatriene-β-ketolactone	Aspergillus stellatus
BGC0002168	1.00	Polyketide	decumbenone a, calbistrin A, calbistrin C, decumbenone B, decumbenone c, dioic acid moiety	Aspergillus stellatus
BGC0002736	0.32	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0000687	0.31	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0000631	0.31	Terpene	botcinin H, botcinin I, botcinin J, cinbotolide D, botcinin K	Botrytis cinerea B05.10
BGC0000677	0.31	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001317	0.31	Terpene	lupeol	Lotus japonicus
BGC0000685	0.29	Terpene	brassicicene C	Alternaria brassicicola ATCC 96836
BGC0000688	0.28	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0001219	0.28	Polyketide	shanorellin	Chaetomium globosum CBS 148.51

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002170	1.00	Polyketide	4-methyl-5-dimethyltetradecahexaene-β-ketolactone, 4-methyl-5-methylheptatriene-β-ketolactone	Aspergillus stellatus
BGC0002168	1.00	Polyketide	decumbenone a, calbistrin A, calbistrin C, decumbenone B, decumbenone c, dioic acid moiety	Aspergillus stellatus
BGC0002736	0.66	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0000687	0.65	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0000631	0.65	Terpene	botcinin H, botcinin I, botcinin J, cinbotolide D, botcinin K	Botrytis cinerea B05.10
BGC0000677	0.65	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001317	0.64	Terpene	lupeol	Lotus japonicus
BGC0000685	0.62	Terpene	brassicicene C	Alternaria brassicicola ATCC 96836
BGC0000688	0.62	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0001219	0.62	Polyketide	shanorellin	Chaetomium globosum CBS 148.51

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 1753 - 36500:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

Ev460pks

PKS_AT (550..866): pk

ATSignature: Methylmalonyl-CoA, Malonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 54.2%; Malonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 56.1
Methylmalonyl-CoA: 50.7
Ethylmalonyl-CoA: 30.3
Malonyl-CoA: 28.7
trans-1,2-CPDA: 19.0
Propionyl-CoA: 18.9
Isobutyryl-CoA: 18.8
fatty_acid: 14.7
inactive: 14.2
3-Methylbutyryl-CoA: 12.3
Benzoyl-CoA: 11.9
CHC-CoA: 0.0
Acetyl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0