LOCUS       BGC0002171              7351 bp    DNA     linear   PLN 12-OCT-2011
DEFINITION  Aspergillus niger ATCC 1015, whole genome shotgun sequence.
ACCESSION   BGC0002171
VERSION     BGC0002171
KEYWORDS    .
SOURCE      Aspergillus niger ATCC 1015
  ORGANISM  Aspergillus niger ATCC 1015
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     URL -- http://www.jgi.doe.gov/aspergillus
            JGI Project ID: 4000237
            Source DNA is available from Ziyu Dai (ziyu.dai@pnl.gov)
            Culture Source: ATCC: ATCC 1015, FGSC A1144 (Kevin McCluskey
            (mccluskeyk@umkc.edu)
            Contacts: Scott Baker (scott.baker@pnl.gov)
            Igor Grigoriev (ivgrigoriev@lbl.gov)
            Annotation done by the JGI and the Aspergillus niger Consortium.
            This project consists of 24 contigs. We have associated 21 Contigs
            with chromosomes 1-8. Three contigs could not be placed on any of
            the chromosomes.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:05:11
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7351
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7351
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1752:7317]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1753..7317
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..7351
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1752:7317]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      1753..7317
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..7351
                     /SMILES="NC([*])C(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="chemical_hybrid"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..7351
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002171"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..7351
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(<9..>596)
                     /locus_tag="ASPNIDRAFT_41845"
     mRNA            complement(<9..>596)
                     /locus_tag="ASPNIDRAFT_41845"
                     /product="hypothetical protein"
     CDS             complement(9..596)
                     /codon_start=1
                     /db_xref="JGIDB:Aspni5_41845"
                     /locus_tag="ASPNIDRAFT_41845"
                     /product="hypothetical protein"
                     /protein_id="EHA27897.1"
                     /transl_table=11
                     /translation="MGQSHLDIGVGTGYYPAKSLKAGAKCTEITLLDLSPNSLQATEQR
                     ILETVGREAVRVNTVVASALEPLPFDKAKKFNSISVFFLLHCMPGTPEEKCKLFDVVRP
                     HLAEDGVLVGTTVLGQGVPINWLGQKMMNSYNNNTKSFHNSEDNKAQFDEGLRRNFEEV
                     DSWIMGQVMLFKARKPRQQDAITNVVPKDNLD"
     gene            <1753..>7317
                     /locus_tag="ASPNIDRAFT_41846"
     mRNA            <1753..>7317
                     /locus_tag="ASPNIDRAFT_41846"
                     /product="hypothetical protein"
     CDS             1753..7317
                     /NRPS_PKS="Domain: AMP-binding (24-423). E-value: 9.3e-102.
                     Score: 332.5. Matches aSDomain:
                     nrpspksdomains_ASPNIDRAFT_41846_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (529-597). E-value: 4.5e-15. Score:
                     47.5. Matches aSDomain:
                     nrpspksdomains_ASPNIDRAFT_41846_PCP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (619-1050). E-value:
                     8.7e-164. Score: 537.3. Matches aSDomain:
                     nrpspksdomains_ASPNIDRAFT_41846_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1161-1455). E-value: 2.6e-97.
                     Score: 317.6. Matches aSDomain:
                     nrpspksdomains_ASPNIDRAFT_41846_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP (1779-1850). E-value: 5.8e-16.
                     Score: 50.5. Matches aSDomain:
                     nrpspksdomains_ASPNIDRAFT_41846_ACP.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR000794"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="JGIDB:Aspni5_41846"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     340.6; E-value: 2.1e-103)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ASPNIDRAFT_41846"
                     /note="GO_function: GO:3824; cofactor binding - catalytic
                     activity [Evidence 16740] [PMID 48037]; GO_process:
                     GO:6633; metabolic process - fatty acid biosynthetic
                     process [PMID 8152]"
                     /product="hypothetical protein"
                     /protein_id="EHA27898.1"
                     /sec_met_domain="AMP-binding (E-value: 3.9e-115, bitscore:
                     371.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.2e-14, bitscore:
                     39.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 9.6e-177, bitscore:
                     575.1, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 9.2e-99, bitscore: 317.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPEDDQNLTDDPSKLGHNVVSLFDQTQTRYSPKAAIVCGEHTLT
                     YGALASDSDRLACLLLSRGISRGHVVALALDRTPDLIMFILGVLKAGATYVPVDPALPP
                     ERVNQMLDDEALRLVIVSPVSTKGGAGTGRYDYGNKAVCCTTSELQDQMRYQADKRPAV
                     DIQPDDIAYILYTSGSTGKPKGVEIHHAAICNYALSVHQRPGCTDQDRVLFKSTISFDM
                     AAFEIYVPLLCGATVVQAQAHDIRDPRALMHLIDRHSVTFSVATPTILQMMLDSGWCGT
                     PGFSKLVTGGEALSPRLAERLTACVEEVWNLYGPTETTASVAAWKVQVGEDILIGTPNP
                     NTRLYVLDADLQPVPVGSTGELYISGAGVARGYRNNPERTKAAFLPDPFWEGHTMYKSG
                     DLACFLDSRRLAVIGRADTQIKIRGQRIDPGDVEASITAHADIANAVVVNRDERLVAYC
                     IRKPGVGSAEVPLAKLLRPWLEDRLPGYMVPSFFVEVDRFPSTLNGKVDLRALPDPIST
                     ITPAKIPASTLTQQLLAIWTDVLGHGQIGMQDSFFHIGGNSASIIQIQTKLEKLLGRPV
                     PVPKLYEHFTIANLAAYLSDQTQTNEVTEETKNPAGNDTTGEDIAVISMACRLPGDIHT
                     PEELWKALISGTDAVTRVPEERWDADAIYDPDPEARGKSYSTGGGFVRDAMDFDAQFFG
                     ISPREARAIDPAQTMILETCWEGFERAGYGTKSLRGSQTGVFIGTGNSSVDDGQLSAAG
                     TEKFEGHLGLGTAPSSLSGRVAYALGLEGPTMTLDAGCAASLVATHVACSALRQGECDM
                     AVAGGVTFLPSPGLHIEFSRIRVASPDGRSRPFSADAAGMGLGEGASAVVLKRLSDAQR
                     DNDHIHAIIRGSAVNHGGRGASMTAPSGPGQKRVVRAALAAARLKPYDIDYVEAHGTGT
                     RLGDPVEASALAEVFSSSRDDITGPLRIGSSKSNIAHTQAAAGLAGLIKVALAMQHTML
                     PQTLHSSQPSPLIDWVGGKLQLLQRPMAWLPRTNDPTAPRRAGINSFGLSGTNAHAIIE
                     EPPRAHSNANGADDDDNDDNARLPLPLPFLLSAYTSEALRQQAQKLCNHLSSATAQTKL
                     SDVSYSLATTRTHFPRRIILAAQDKTELMGRLASIIDNGVPATADNNKTARVAMLFSGQ
                     GTERARMGKGLAERHLVFRNTVSHIAELFESVLEKPLLDVMWAEPESEAASLLRRTDYA
                     QPAIFTLQVALWRLWQSWGVQPAVVLGHSVGEIAAAHVAGIMNLADACRLVAARGKLMH
                     ALPESGSMVALEAGVDEVTSAIEQLSARDRVSIASINTPTQVVASGEMDVIDKLAAYFE
                     AQNRSSKILKTSRAFHSHHLDESMLALLRAVAETIVFQEQTLPIVSTVTGKLAEPGQLS
                     SADYWVRQARNPVLFAEGMQTLADQGANCFVELGPASTLCGMGASCLDGDLSQTSKVAG
                     REGAKNLVWLHSLNPKSDDALVIHNSLSDLHIRKVEIDWAAFFKDIGGRRIQLPTYAFQ
                     RHRYWLDGLRPIYSDKSSGQPSGQSPSGCPQPTGQIQVGWHTIDASSQYSNSTWGLLCP
                     ASDAPWMSPVKEALLHAGKQPVTVNQLAEAKAMSGVLCFWESDSEDDMISKASEQLQTV
                     SRMKFSPWVVWVTRGAVGAGNMGEASLWGVMRSARVKYPQLCLRIVDLEGDVNIATATK
                     LCSILMMSTEPECVVLGERVLVPRMQFQMQAQVQEVQKHSKLCVNGQETTNGATAAADP
                     NGTDSFENKIRMAGPEERAMMLQGLVRGITAKALGVATAEEVDMHQGFMDVGVGSLGAI
                     QMRKELSAQTGVKLPANLTRVYPDPISLSDALQKQVEGQ"
     aSDomain        1825..3021
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPNIDRAFT_41846_AMP-binding.1"
                     /evalue="9.30E-102"
                     /label="ASPNIDRAFT_41846_AMP-binding.1"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="423"
                     /protein_start="24"
                     /score="332.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DQTQTRYSPKAAIVCGEHTLTYGALASDSDRLACLLLSRGISRGH
                     VVALALDRTPDLIMFILGVLKAGATYVPVDPALPPERVNQMLDDEALRLVIVSPVSTKG
                     GAGTGRYDYGNKAVCCTTSELQDQMRYQADKRPAVDIQPDDIAYILYTSGSTGKPKGVE
                     IHHAAICNYALSVHQRPGCTDQDRVLFKSTISFDMAAFEIYVPLLCGATVVQAQAHDIR
                     DPRALMHLIDRHSVTFSVATPTILQMMLDSGWCGTPGFSKLVTGGEALSPRLAERLTAC
                     VEEVWNLYGPTETTASVAAWKVQVGEDILIGTPNPNTRLYVLDADLQPVPVGSTGELYI
                     SGAGVARGYRNNPERTKAAFLPDPFWEGHTMYKSGDLACFLDSRRLAVIGRADTQIKIR
                     "
     aSModule        1825..3543
                     /complete
                     /domains="nrpspksdomains_ASPNIDRAFT_41846_AMP-binding.1"
                     /domains="nrpspksdomains_ASPNIDRAFT_41846_PCP.1"
                     /locus_tags="ASPNIDRAFT_41846"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2008..2049
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_41846_0001"
                     /evalue="4.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="99"
                     /protein_start="85"
                     /score="16.7"
                     /tool="antismash"
                     /translation="LGVLKAGATYVPVD"
     CDS_motif       2263..2322
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_41846_0002"
                     /evalue="3.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="190"
                     /protein_start="170"
                     /score="28.9"
                     /tool="antismash"
                     /translation="AYILYTSGSTGKPKGVEIHH"
     CDS_motif       2815..2904
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_41846_0003"
                     /evalue="2.60E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="384"
                     /protein_start="354"
                     /score="48.5"
                     /tool="antismash"
                     /translation="PVGSTGELYISGAGVARGYRNNPERTKAAF"
     CDS_motif       2989..3051
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_41846_0004"
                     /evalue="5.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="433"
                     /protein_start="412"
                     /score="31.4"
                     /tool="antismash"
                     /translation="IGRADTQIKIRGQRIDPGDVE"
     aSDomain        3340..3543
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPNIDRAFT_41846_PCP.1"
                     /evalue="4.50E-15"
                     /label="ASPNIDRAFT_41846_PCP.1"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="597"
                     /protein_start="529"
                     /score="47.5"
                     /tool="antismash"
                     /translation="QQLLAIWTDVLGHGQIGMQDSFFHIGGNSASIIQIQTKLEKLLGR
                     PVPVPKLYEHFTIANLAAYLSDQ"
     aSDomain        3610..4902
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPNIDRAFT_41846_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="8.70E-164"
                     /label="ASPNIDRAFT_41846_PKS_KS.1"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="1050"
                     /protein_start="619"
                     /score="537.3"
                     /tool="antismash"
                     /translation="IAVISMACRLPGDIHTPEELWKALISGTDAVTRVPEERWDADAIY
                     DPDPEARGKSYSTGGGFVRDAMDFDAQFFGISPREARAIDPAQTMILETCWEGFERAGY
                     GTKSLRGSQTGVFIGTGNSSVDDGQLSAAGTEKFEGHLGLGTAPSSLSGRVAYALGLEG
                     PTMTLDAGCAASLVATHVACSALRQGECDMAVAGGVTFLPSPGLHIEFSRIRVASPDGR
                     SRPFSADAAGMGLGEGASAVVLKRLSDAQRDNDHIHAIIRGSAVNHGGRGASMTAPSGP
                     GQKRVVRAALAAARLKPYDIDYVEAHGTGTRLGDPVEASALAEVFSSSRDDITGPLRIG
                     SSKSNIAHTQAAAGLAGLIKVALAMQHTMLPQTLHSSQPSPLIDWVGGKLQLLQRPMAW
                     LPRTNDPTAPRRAGINSFGLSGTNAHAIIEEP"
     aSModule        3610..7302
                     /complete
                     /domains="nrpspksdomains_ASPNIDRAFT_41846_PKS_KS.1"
                     /domains="nrpspksdomains_ASPNIDRAFT_41846_PKS_AT.1"
                     /domains="nrpspksdomains_ASPNIDRAFT_41846_ACP.1"
                     /locus_tags="ASPNIDRAFT_41846"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       4096..4143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_41846_0005"
                     /evalue="2.60E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="797"
                     /protein_start="781"
                     /score="10.5"
                     /tool="antismash"
                     /translation="GPTMTLDAGCAASLVA"
     CDS_motif       4516..4563
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_41846_0006"
                     /evalue="1.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="937"
                     /protein_start="921"
                     /score="13.7"
                     /tool="antismash"
                     /translation="YVEAHGTGTRLGDPVE"
     aSDomain        5236..6117
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPNIDRAFT_41846_PKS_AT.1"
                     /evalue="2.60E-97"
                     /label="ASPNIDRAFT_41846_PKS_AT.1"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="1455"
                     /protein_start="1161"
                     /score="317.6"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFSGQGTERARMGKGLAERHLVFRNTVSHIAELFESVLEKPLLDV
                     MWAEPESEAASLLRRTDYAQPAIFTLQVALWRLWQSWGVQPAVVLGHSVGEIAAAHVAG
                     IMNLADACRLVAARGKLMHALPESGSMVALEAGVDEVTSAIEQLSARDRVSIASINTPT
                     QVVASGEMDVIDKLAAYFEAQNRSSKILKTSRAFHSHHLDESMLALLRAVAETIVFQEQ
                     TLPIVSTVTGKLAEPGQLSSADYWVRQARNPVLFAEGMQTLADQGANCFVELGPASTLC
                     GMGASCLDGDLSQ"
     CDS_motif       5410..5478
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_41846_0007"
                     /evalue="3.70E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="1242"
                     /protein_start="1219"
                     /score="16.7"
                     /tool="antismash"
                     /translation="RRTDYAQPAIFTLQVALWRLWQS"
     CDS_motif       5482..5604
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_41846_0008"
                     /evalue="1.50E-21"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="1284"
                     /protein_start="1243"
                     /score="68.6"
                     /tool="antismash"
                     /translation="GVQPAVVLGHSVGEIAAAHVAGIMNLADACRLVAARGKLMH"
     CDS_motif       5968..6003
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_41846_0009"
                     /evalue="9.40E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="1417"
                     /protein_start="1405"
                     /score="12.7"
                     /tool="antismash"
                     /translation="YWVRQARNPVLF"
     CDS_motif       6346..6381
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_41846_0010"
                     /evalue="3.60E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="1543"
                     /protein_start="1531"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="IYSDKSSGQPSG"
     aSDomain        7090..7302
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPNIDRAFT_41846_ACP.1"
                     /evalue="5.80E-16"
                     /label="ASPNIDRAFT_41846_ACP.1"
                     /locus_tag="ASPNIDRAFT_41846"
                     /protein_end="1850"
                     /protein_start="1779"
                     /score="50.5"
                     /tool="antismash"
                     /translation="GLVRGITAKALGVATAEEVDMHQGFMDVGVGSLGAIQMRKELSAQ
                     TGVKLPANLTRVYPDPISLSDALQKQ"
ORIGIN
        1 ggttcttctc aatccaagtt gtctttcgga actacattgg tgatggcatc ttgttgtctt
       61 ggcttcctcg ccttgaagag cataacctgg cccatgatcc acgaatccac ctcctcaaag
      121 ttccgacgaa ggccctcatc aaactgagcc ttgttgtcct ccgagttatg gaaagacttt
      181 gtattgttgt tgtagctgtt catcattttc tgtcccagcc agttgattgg tacaccctga
      241 ccaaggacag tcgttcccac aagcacgccg tcctccgcca gatgcggccg caccacgtcg
      301 aacagcttgc acttttcttc aggtgtcccc ggcatacagt gcaacaggaa gaaaacacta
      361 attgagttga actttttggc cttgtcgaag ggaagtggct ccagggccga agccacgaca
      421 gtgttcacgc ggaccgcctc ccggcctacc gtctccagga tgcgctgctc ggtagcctga
      481 agcgagttgg gactgaggtc caggagggtg atttcagtac atttggcgcc ggcctttagg
      541 ctctttgctg ggtagtagcc tgtgccgacg ccgatgtcga ggtggctctg acccatggcg
      601 gccttgaaca atgggagctg gacggttgag gttgggcatt tccatgcaaa cttgttggaa
      661 acccatagga cccagaaatc atagaaatag cggagaagaa atggagtata gagtgcaatc
      721 ccttcgttca aggatgtagg tgtttttggt gaagctgtca tggttgattt tgtagtgagg
      781 gctgcgtgtg agaaggtgtg cgtgtttgcg tgtgccttct cttttctttc tttccttttc
      841 ccttggaaag gaattacggg caagaaaaca atgacgagga agaaaaggac acccctggtt
      901 aatgagaaga atgtatggaa agcttaacac gaagaaacta tccaagcctt gtgaatgtca
      961 gtctcgccca gggttcgtct tatcctttga taacggcaca tgtatcatct cggccttgtt
     1021 gttctccaat attgtcttca attattgctt gacaggaatg ttggctatct tatctcttct
     1081 ggaaactttc tccccctcac cccttgccta cattatttcc cgatgagcga tttttttcca
     1141 ttgttcttcg acccagagta gaccattcca tgaggatgcc ttgccggaaa aacattcctg
     1201 tgcgacaagc agaagtcatg tcataagtta cactgacaac cgtttcggca gatatatgtc
     1261 tcggtaaccc tatcacggtt aaggcgagac tctaaacagt agtgttccct tgcctgggat
     1321 tccatccatc agctatgcat tccatccatt caggcaatgg tcaacttcta ctgttgaaca
     1381 gggctggcat ccatctgtgt ctagacattt agtgatcacg acatcgtgga ccgggcagca
     1441 gccaattcca ccatgataat gcatccagcc tgcggatcct taggaatgac gcgtatcaaa
     1501 gaccgcaggg aatagggtcc tcatgacaca ccgcagctcc tgtttgggta tcggtataat
     1561 gccggcctat gatatacggg cctggtaagt gtggtgccac ctctttctgc ctgagaacta
     1621 gacaatatac cctaccagcc taacttgata tatcgtattc ccatctttgt tctcatgaat
     1681 tttcgttctt aatcctgtct tccacaggat tagttcataa caaagaagaa tagcaagaaa
     1741 gaatcgacag ccatggtacc agaggacgac caaaacctca ctgatgaccc atccaagctc
     1801 ggtcacaatg tcgtttccct cttcgaccaa actcagaccc gatactcccc aaaggctgcc
     1861 atagtatgcg gggagcatac cctcacatac ggtgctcttg catctgattc ggatcgcctg
     1921 gcctgcctcc tcctgtcgcg aggcatcagc cgtggccatg tggtggctct tgcactggac
     1981 cgcacaccag acctgatcat gttcattctc ggcgtcttga aagcgggtgc gacatatgta
     2041 cccgttgatc ctgctttacc ccccgagcgt gtcaaccaga tgctggatga tgaagcgctg
     2101 cgtctggtga tagttagtcc tgttagtacc aaaggggggg cgggcaccgg tcgatatgat
     2161 tatggcaata aggcagtctg ctgcaccacg agcgagctcc aagatcagat gagatatcaa
     2221 gcggacaaga ggccagctgt ggatattcag ccagatgaca ttgcctatat tctgtacaca
     2281 tctggatcca caggcaagcc taagggcgtg gaaattcatc acgccgctat atgcaactat
     2341 gccctgtcgg tacaccaaag acctggctgt actgaccagg accgcgtgct gttcaaaagc
     2401 accatctcgt tcgatatggc cgcgtttgag atatacgtgc cattgctgtg cggcgctaca
     2461 gtcgtgcagg cacaggcaca tgatatcagg gatccccgcg cgctgatgca tctcattgat
     2521 cggcacagcg tcaccttctc cgtggcgacg ccgaccattc tacagatgat gctggacagc
     2581 ggttggtgcg gcacgccagg cttctctaag ctggttaccg gtggcgaggc actgtcacct
     2641 cgcctggcag agcgcctaac cgcgtgtgtt gaagaagtat ggaaccttta cggcccgact
     2701 gagacaacag ccagcgtggc tgcttggaaa gttcaagtcg gtgaggacat attgattgga
     2761 acgcctaacc cgaacacacg gctatatgtc ctcgacgccg acttgcagcc cgtgccggtt
     2821 ggcagcaccg gcgaactata tattagcgga gcaggcgttg ctcgtggata tcggaacaat
     2881 ccagagcgca ccaaggctgc gtttcttccg gatcctttct gggaaggcca tactatgtac
     2941 aagtcaggag acttggcatg cttcttggat tccaggagac tggccgtcat cggtcgggca
     3001 gacacgcaaa tcaagattcg cgggcaaaga attgatcctg gcgatgttga ggcatccatc
     3061 acagctcacg cggatattgc caatgccgtt gtggtcaacc gagacgagcg gctcgtcgca
     3121 tactgtatac gaaagccggg cgttggcagc gccgaggttc ctctagccaa gttgctacgc
     3181 ccctggctag aagaccgcct tcccgggtac atggtcccct cgttcttcgt cgaagtcgat
     3241 cgatttcctt ctacgctcaa cggcaaagtg gatctccggg cactgcccga tcccatctcg
     3301 accatcacac cggcgaaaat accagcttct acactgacac aacagctgct ggctatatgg
     3361 accgatgtgc taggccacgg tcagattggc atgcaggaca gcttcttcca cattggcggc
     3421 aactcggcga gcatcattca gatccagacc aaactggaga agcttctggg tcggccagtg
     3481 ccggtgccaa aactgtatga gcacttcacc attgccaacc ttgctgcata tctctctgat
     3541 caaacccaga ccaatgaggt taccgaagag acgaaaaacc ctgctgggaa cgataccacc
     3601 ggtgaagata ttgctgtcat ttccatggcg tgcagactgc ccggcgatat tcacacgcca
     3661 gaagaacttt ggaaggctct catcagcggc accgatgccg tcaccagggt tcctgaggag
     3721 cgctgggatg ctgatgccat ttacgacccg gacccggagg cccgcggcaa gtcctacagc
     3781 acgggtggcg gcttcgtcag ggacgccatg gatttcgatg cgcaattctt tggaatctcc
     3841 cctcgcgagg cccgggctat cgaccccgcg cagaccatga tcctggaaac atgctgggag
     3901 ggcttcgaac gggcaggcta tggcaccaag tccctgcggg gcagccagac tggtgtcttc
     3961 atcgggaccg gtaacagttc tgtggatgac ggccagctaa gcgccgccgg cacagagaag
     4021 tttgaaggac accttggact tggcacggcg ccaagctcgc tctctggtcg cgtagcatat
     4081 gctctggggc ttgagggtcc tacgatgact ttggatgctg ggtgcgctgc ctcgctggtc
     4141 gccacgcatg tagcatgctc agcacttcgc caaggcgagt gtgacatggc tgtagctggc
     4201 ggcgtcacat tcttgccttc tcctggtttg catattgagt ttagccgcat tcgcgttgca
     4261 tcaccagatg gtcgctcgcg accgttttca gcggacgcag ctgggatggg actgggtgaa
     4321 ggtgcctcgg ctgtggttct gaagcgtctg tcggatgcgc agcgcgacaa cgatcatatc
     4381 catgctataa ttcgtggttc agcggtcaat cacggcggtc gcggcgctag catgacagca
     4441 ccgagtggac caggccagaa gcgtgttgtc cgcgcagcgc tggcggctgc gcgcctaaag
     4501 ccatatgata ttgactatgt cgaggcgcat gggactggca ccagactagg agatcccgtc
     4561 gaggcctcag ctttggcgga agtatttagc agcagccgcg atgatattac tgggccgctg
     4621 aggattggtt cgtcaaagtc caatatcgca catacgcagg cggcggccgg cctcgccggc
     4681 cttatcaaag tggctctggc aatgcaacac accatgctgc cacagacact gcatagtagt
     4741 cagcccagcc ctctgatcga ctgggtgggt ggcaagttgc agcttctcca acggccaatg
     4801 gcatggctac ccagaacaaa cgatccgact gctccgcgaa gagcaggaat taactcgttc
     4861 ggattatcgg gcactaacgc ccatgctata attgaagagc ccccgagggc tcactcaaat
     4921 gctaatggcg ccgatgatga tgataatgat gataatgcga ggttgccttt gccgctgcca
     4981 ttcctcctgt ccgcctatac aagtgaagca ctgcgtcagc aagcacagaa attatgcaat
     5041 cacctctcca gtgccactgc acaaaccaag ctgtctgatg tatcctactc gctggcgact
     5101 actcgtacgc atttcccacg acgtatcatt cttgcagcac aagacaagac tgaacttatg
     5161 ggcaggctag caagcattat cgacaacgga gtaccggcaa ctgctgacaa caacaaaaca
     5221 gctcgcgtgg cgatgttgtt ctctgggcag ggcactgaac gggccagaat gggcaagggt
     5281 cttgctgaac gccaccttgt attccgcaac actgtcagtc acattgcaga actcttcgag
     5341 tcggtcctgg aaaaaccact gctggatgtc atgtgggcag agcctgagag cgaggccgct
     5401 tctctactgc ggcgtacgga ttatgcccaa ccagctatct ttacactcca ggtagcacta
     5461 tggagactgt ggcagagctg gggtgtccag ccagcagtcg tgctaggcca tagcgttggc
     5521 gaaattgcgg ccgcgcacgt cgccggaatc atgaatctag cagacgcttg ccgcttggtc
     5581 gcagcacgag ggaaactgat gcatgcgctg cctgaaagtg gtagtatggt ggcgcttgaa
     5641 gccggcgtag acgaggtcac ttcagccatc gagcagctca gtgcacgcga cagggtgtcg
     5701 attgccagta tcaacacccc aacgcaagtg gttgcatctg gagaaatgga tgtcattgac
     5761 aaattagcag cttatttcga ggctcaaaac cggtcttcta aaatcctcaa aaccagtcgc
     5821 gcgttccatt cgcaccatct ggatgaaagc atgcttgcat tgttacgcgc cgtcgcagaa
     5881 accattgtgt tccaggagca aacgctacct atcgtcagca cagtcacagg aaaactggca
     5941 gagcctggac aacttagcag tgcggattac tgggttcgac aagctcgcaa tcctgtcctg
     6001 ttcgctgaag gcatgcagac cctcgctgac cagggcgcga attgctttgt tgaattgggt
     6061 ccagcatcga cactgtgtgg tatgggagct tcatgtctcg atggggacct tagtcagacg
     6121 agcaaagtgg ccggccgcga aggcgcaaag aacctggtct ggctgcactc gttaaacccc
     6181 aagagcgacg acgctctagt gatccacaac agtctctccg acctgcacat acgaaaagtg
     6241 gagatcgact gggcagcgtt cttcaaagac attggcgggc gccgcatcca gctacctacg
     6301 tacgcatttc agcgacatcg gtattggctg gacggtttgc ggccaatata cagcgataaa
     6361 tcatctggcc aaccttctgg ccagtctcct tcgggttgcc cccaacccac tggccaaatt
     6421 caagttggat ggcacactat tgacgcgagt agccagtatt ccaattcaac ttggggtctc
     6481 ctctgtccag caagtgatgc gccatggatg tcaccggtga aggaagcatt gttgcacgcc
     6541 ggaaagcaac ctgtcacggt caatcagctc gcggaagcca aagcgatgag cggcgtgctt
     6601 tgtttctggg aatcagacag tgaagacgac atgatctcca aggcatctga gcaattgcag
     6661 accgtgtcac gaatgaagtt ctctccctgg gtagtctggg tgacgcgggg tgctgtggga
     6721 gccggaaata tgggcgaggc atcgctatgg ggtgtgatgc gaagcgcgcg cgtcaaatat
     6781 cctcaactct gtctacgtat cgtggacttg gaaggtgacg ttaacatcgc tacagccacc
     6841 aaactctgct caatcttgat gatgagtacc gaacctgaat gtgttgtgct tggtgaacga
     6901 gtgctcgtcc cgcgaatgca gtttcagatg caggcgcagg tccaggaggt ccagaagcat
     6961 agtaagctgt gcgtaaacgg tcaagagacg accaacggag caaccgcagc tgcagatcca
     7021 aatgggacgg acagcttcga gaacaagatc aggatggctg ggcccgagga gagggcgatg
     7081 atgcttcagg gactagtacg ggggataact gccaaagcac ttggtgtggc gactgctgag
     7141 gaagtagata tgcaccaggg gttcatggat gttggagtgg gttcattagg agcaattcaa
     7201 atgcgcaaag agctttcggc gcagacaggg gtcaagttgc cagctaactt gaccagagtg
     7261 tatccggatc ctatctcact ttccgatgct ctgcagaagc aggtagaagg tcagtagcta
     7321 gcaggttctt tatagtcaga tagaataata g
//
