LOCUS       BGC0002176             21199 bp    DNA     linear   CON 11-MAR-2015
DEFINITION  Fusarium graminearum PH-1 chromosome 1, whole genome shotgun
            sequence.
ACCESSION   BGC0002176
VERSION     BGC0002176
KEYWORDS    WGS.
SOURCE      Fusarium graminearum PH-1 (Gibberella zeae PH-1)
  ORGANISM  Fusarium graminearum PH-1
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
            Fusarium.
REFERENCE   1  (bases 1 to 11697295)
  AUTHORS   Cuomo,C.A., Guldener,U., Xu,J.R., Trail,F., Turgeon,B.G., Di
            Pietro,A., Walton,J.D., Ma,L.J., Baker,S.E., Rep,M., Adam,G.,
            Antoniw,J., Baldwin,T., Calvo,S., Chang,Y.L., Decaprio,D.,
            Gale,L.R., Gnerre,S., Goswami,R.S., Hammond-Kosack,K., Harris,L.J.,
            Hilburn,K., Kennell,J.C., Kroken,S., Magnuson,J.K., Mannhaupt,G.,
            Mauceli,E., Mewes,H.W., Mitterbauer,R., Muehlbauer,G.,
            Munsterkotter,M., Nelson,D., O'donnell,K., Ouellet,T., Qi,W.,
            Quesneville,H., Roncero,M.I., Seong,K.Y., Tetko,I.V., Urban,M.,
            Waalwijk,C., Ward,T.J., Yao,J., Birren,B.W. and Kistler,H.C.
  TITLE     The Fusarium graminearum genome reveals a link between localized
            polymorphism and pathogen specialization
  JOURNAL   Science 317 (5843), 1400-1402 (2007)
   PUBMED   17823352
REFERENCE   2  (bases 1 to 11697295)
  AUTHORS   Birren,B., Lander,E., Galagan,J., Nusbaum,C., Devon,K., Ma,L.-J.,
            Jaffe,D., Butler,J., Alvarez,P., Gnerre,S., Grabherr,M., Kleber,M.,
            Mauceli,E., Brockman,W., MacCallum,I.A., Young,S., LaButti,K.,
            DeCaprio,D., Crawford,M., Koehrsen,M., Engels,R., Montgomery,P.,
            Pearson,M., Howarth,C., Larson,L., White,J., O'Leary,S., Kodira,C.,
            Zeng,Q., Yandava,C., Alvarado,L., Kistler,C., Xu,J.-R. and Trail,F.
  CONSRTM   The Broad Institute Genome Sequencing Platform
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2008) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##antiSMASH-Data-START##
            Version     :: 8.dev-5707d64f
            Run date    :: 2025-08-15 21:10:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start :: 0
            Orig. end   :: 21199
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     region          1..21199
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /subregion_numbers="1"
                     /tool="antismash"
     subregion       1..21199
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002176"
                     /subregion_number="1"
                     /tool="antismash"
     cand_cluster    1..21199
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21199
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:11199](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11199
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     mRNA            join(<1518..1846,1895..2286,2341..2446,2496..>3261)
                     /locus_tag="FGSG_10394"
                     /product="hypothetical protein"
     gene            <1518..>3261
                     /locus_tag="FGSG_10394"
     mRNA            complement(join(<3495..4569,4617..5088,5151..>5409))
                     /locus_tag="FGSG_10395"
                     /product="hypothetical protein"
     gene            complement(<3495..>5409)
                     /locus_tag="FGSG_10395"
     mRNA            complement(join(6496..6814,6867..7199))
                     /locus_tag="FGSG_10396"
                     /product="hypothetical protein"
     gene            complement(6496..7199)
                     /locus_tag="FGSG_10396"
     mRNA            join(9966..10261,10315..10467,10543..10862,10914..11438)
                     /locus_tag="FGSG_10397"
                     /product="hypothetical protein"
     gene            9966..11438
                     /locus_tag="FGSG_10397"
     CDS             join(10001..10261,10315..10467,10543..10862,10914..11199)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /locus_tag="FGSG_10397"
                     /product="hypothetical protein"
                     /protein_id="ESU17105.1"
                     /sec_met_domain="T1TS (E-value: 2.3e-19, bitscore: 56.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLATPTLSNFDKPSLPSSEGGDPALAARLQPLYSRFLTDLDLQPE
                     YRRHESEKLMEEVLKFAKSTGVPHDLNSHSYQSLMVGYTYADNCLPYHDIEVKVYVAIY
                     TWLATICDDAEALGIIDDVQLFEQRFILGEEQPTVLLRAFADQLKLTYKLYHPLVANLI
                     LCSSLNLLTSTSLVARKGIKEKGDHPSKGGNYFAWYIRERDGVGEAYSWFTFPKRQFPN
                     LDIPIEAIEDMTRFIAYLNDVLSFYKESLAGETHNYINHTAAYEGVDSDAALHKTAQDT
                     IDCARRIESVLAGKGEYEKAWRLHASGYLQMHVQRGRYRLIEVGVGDAPDVHEVIKKI"
     mRNA            complement(join(<12477..13328,13741..>13833))
                     /locus_tag="FGSG_10398"
                     /product="hypothetical protein"
     gene            complement(<12477..>13833)
                     /locus_tag="FGSG_10398"
     mRNA            <14222..>15178
                     /locus_tag="FGSG_10399"
                     /product="hypothetical protein"
     gene            <14222..>15178
                     /locus_tag="FGSG_10399"
     mRNA            join(<15835..15883,15977..16287,16336..16384,16432..>16571)
                     /locus_tag="FGSG_10400"
                     /product="hypothetical protein"
     gene            <15835..>16571
                     /locus_tag="FGSG_10400"
     mRNA            complement(join(<16981..17369,17419..>18100))
                     /locus_tag="FGSG_10401"
                     /product="hypothetical protein"
     gene            complement(<16981..>18100)
                     /locus_tag="FGSG_10401"
ORIGIN
        1 tatctgtcaa tgaacaagga atcgatccaa ggattagtcg cattagccgg gggtgagaag
       61 ccagacatag tcactatcag aattgctgtc gtccgcgtag acgaagacag attcaacaac
      121 aaagccctcc ttttccaaga gcggagcgat tacccccacg tccgcgaaat actacaatgc
      181 gatctcgacg actcgaacac gctcgtacgc gatgtcatca gacgaaaaat caccaacgat
      241 ttgggccttg acgcttggaa ggtcgtgggc accacagaac ctgagttcta ggcacactgc
      301 gagggtgggc gaatcttgga aaatcatgcg gtgctgggct atgtgatcca ggtttggccc
      361 agtgacaaag gatacacgca caaacccccg tatagaggca ttgcctggat caacgaggtt
      421 cgagagccgc gcgaagcgtt cagacaagaa atgatcgagt tgttcagaca cgacatgcgc
      481 gggtttgtgt caaaggtcta tgcactttca tggtggcagg gacagaaaat gaaccagatt
      541 ctactatgac gactagagca tcatgaagag agctggaccc atgttgacgg cggcggataa
      601 cctctagtct aaggtttagg ttataaaaat aaaagaccaa agattattgc ctaagcagca
      661 taaactgatt tgctaatttc gtctcttatg cttctggtat gttataataa caaaagatat
      721 gaatcctacc caggtgtctt gtgtaagcga caaggcgaca aataacaacc ctcagtagga
      781 aacaagagct tggcaaggcc tcagggtatc ggaaaaattg tccgctaaaa gcataaggga
      841 taaaattatt aggtcgtttt atgcagctta gactatactc tttaggctat ttatttctat
      901 accctaagac ttgggaggtt attttttctg cttccccgta gcaaggttag atgccgactt
      961 ggcgacacta gactcggccg gtagatgtgg atagtttcca acgacagccg gtcactagaa
     1021 gaaaattgtt ggattgaatc ggcaaagtaa ctaaactggt atcacaaacc gtcgacgaac
     1081 tgggtccaag tggatatgtc gagtaaaatc tgcaaacact atatatcctt acatccggat
     1141 attaggagtg agatgcatca agaggcaagt tgaataccta gaaccaagag taaatgcttg
     1201 tcgatcttta ttagtaatgt ttcctgtttg aaggatcttt tgtatgcgac gttacccttc
     1261 gaggtttagc caccttccat agcgggcaac cttgaacttc tcatcgacat gggctgatgg
     1321 aacaatcctt ttaatatcag tacgtaacta caactctttg acagttctgt agtggatttg
     1381 cctctgagca cgcaattcct cgtgcttcat ttttagcgga tttaatatgt actacatcaa
     1441 taaactcttt cccatcgact tggtcttgat cttgatttca cctctcgaga tcacttcaac
     1501 tacccaacag taaagccatg gcttattatt ctgaaaaaga caagtcgcca ggcggcggcg
     1561 acgtcgagaa taccccagac agcgatggct tgtccagacg aggtcccacg cagtcagacc
     1621 tgctaagccg ttcgctctcg gcgcgacagg tccagatgat tgccattgga ggtacaatcg
     1681 gtacaggttt attcctgggt actggaaagt cactcgctac aggtggccca gcgtcgatat
     1741 tgattgctta cgctattgtg ggtggcattg tttttactac catgttagct cttggtgaga
     1801 tggcggcgtt tattcccgtg gcaggtagtt tctgtacttt tgcagggtga gttccagtgt
     1861 aattactact gaattaccac taacaaaaaa ccagtcgctt cgtggatgat gcttttggtt
     1921 tcgctctgac ttggaattac tggttcaacg atgctgtatc tacagcctcg gatctcgtcg
     1981 cactgcagct cattctccaa tactggaccg acaacttccc cggctgggct ctgagtctta
     2041 ttttctgggt tgttctcatc gctctcaaca tcatttccgt caaggcctac ggtgaagtcg
     2101 agtactggct cagtctgctc aaggtcatca ccattgttgt ctttatcgtc atgggtattg
     2161 tcgtcaactg tggcggcaac gaaactggag agtatattgg tggcaaatac tggcatttgc
     2221 ctgatgcgcc ttttgttggt ggtattggag gttttgcctc tgtttttgtt actgcttctt
     2281 ttgcttgtaa gtttatccct ggtctcggtg atgaattgga tgaataacta acgatactag
     2341 atggtggaac agagagtatc gccatcactg ctggtgagac caaggatcct accaaaaaca
     2401 tccccaaagt tgtcaagaac gtcttttggc gtatcctcct attctagtaa gttttcctac
     2461 ccacatccct gagttaatca ctaataaaaa tacagtatcc tttcaattct catcatcggc
     2521 ctcaatgtcc cctacaacta ccccgatctc aactccaagg aaacccgcac ttcgccattt
     2581 accattgtct ttgagatgac aggcgccaaa gctgctggaa gtgttatcaa cgctgttatt
     2641 ctaaccagtg ttctttcggc cggaaaccac gctctttttg ctggtgtgag actgatgtac
     2701 actctcgctc ttgagggaca tgcgcctaaa gtactcggaa aactcaacag gaacagagtc
     2761 ccttgggttg ctgttttggt caccggtttt gtagctggtc tttgcttcgg ctcaagtttc
     2821 attggcgctg gacaactgtg gtcctggcta caaaacatcg tcggtgtatc caaccaacta
     2881 agctggatct ccatcggaat cacatcaatc cgcttccgcc aagccctcga gctccaaggc
     2941 aaaacgcatc ttctgccatt caagaattgg acgtacccct atggcccatg gatctgcgtc
     3001 ttcctcaaca gcttcctggt gctagtgcag ggctggagct gtttcagtcc caagtttgac
     3061 gttgtcagct ttatcagctt ttacatcgag ctacccgtca tgctcatcat gtatatcggg
     3121 tggaagcttc tcaaaaagac aaaggttgtt aagttgagcg agatggatct tgagacggat
     3181 gtacatacta ttgaggagaa ggttactgag gaggcggggt ggaagaataa gctgaagaat
     3241 gcggttactt ggttgtttta agggtgcgat tggctagcga tttgatacca cagtacataa
     3301 tgattactgt ttatataaag atatttccac attttaataa gcagaaaagt gtggtaatgt
     3361 tcatgtcatc aaagactcac ttcagaataa agacaacgaa atagtgatac atatggatta
     3421 acaattatat actcaaatgg tgagacctag tctcgataag aagtgaaagg tatagacaca
     3481 cccacacaag aacatcactc cccattacca ccctcagcat actcctcagg cacttccggc
     3541 caagcatcaa caccatcctg aataaccatc atcattccac caagcatgtg gttattgata
     3601 tgacaatgca gaagccacgg accagcatca gcagcatggt atcgaacaac cacccaactc
     3661 ggctcctttt ctgcaggagc agaaaggaac gcatcgcgac gaggtggatt gacgagattg
     3721 aactggtcag ggatctcctt gatggcctct tcaacagagt tccatctaaa atgtccagtt
     3781 ccggcgccaa gcatgtacat cttggatccg tgcttgtgaa tagggtgcgg tggctgggga
     3841 aatagagctg ctacaaagac aagatcgacc cattgaccta gcttggtaga gatggtgacg
     3901 ttattgttga tatatggctg ggggttgaaa agtgttggtt tcccctcgtc aatctccttt
     3961 ggcataagag tagtttcgtt caacgcccag agatacgacg cgcccttaat agccatgctc
     4021 aagttgaacg tgacatcagc agtaggcgat atcggactcg gcgggtaagg gaatgccaca
     4081 gcttggttga agacggcaac ttctttagag gcaggaagac caacgatgtt aatccaaggc
     4141 tcgatatttc cctctgcagc gctgtatcct ttgatagaga ggacagcatg gcctgtgatg
     4201 agctgcggcg cactattggc gttaaagcgc attttgtaat cacccgtatt ggcgatcttg
     4261 atgacgatgg agtatcgatc tccgttggct acaggaatag cttgaacctt ttggggctcg
     4321 atgtaggagc cgtccatggc gtatacccac atatcatggc cgtcgatgga aaagactccg
     4381 ctgacaaagt tgattgcgcc gacgatgtca aaggctagcc atgattccca ttgaccaaag
     4441 tagtttgaga tttcgatggt ctcgagttgt ccgtctgttt ctttgcagcc ggagaatgtg
     4501 cctgggagga gggctgattc gttgcccata ccgcctgcga ggaagttgag ggcggaagcg
     4561 ggtagacatc tagtcatggt cagctctgca atttagactc cagatatagt actcacgcct
     4621 tgtctgtaaa ctcagcacct cctggtacca gtccaaggta cgccttctga atctcattaa
     4681 ggttggcttc aacgacttcc ttgtcaagac actcgactcg tcccttgcca ttaaagagga
     4741 tagagtcata gcacgaatct tcaattccag cagcaagagt catatcccat ttctcctgtg
     4801 aggtgaggtg cacaaagtcg gatatgacga tgggcttgac tttctcaacg gcttctttga
     4861 tcttgttcac ggtgtgttca tccttagaga tgagatggaa tggactcggc tcgtcgtgtc
     4921 gagggtggat gatgattgct ccgtagagac catcctcgat ctggccccgg aagtgggagt
     4981 ggtaccagaa gctgccgtgt tgagatgcgt ggaacttgta ggtgaagctg cttcctggct
     5041 tgatggggtg ttgagttacg cctgggacac catctgacca gggggtacct ttcatttcca
     5101 agcctgactt gttaggtctt tttcgtatac acggaatgaa ttgaacgtac cgtggtaatg
     5161 aactgtaaga tcctctgggg atttgttgtg gacttttaca acaaccatgt catcttgatc
     5221 aatctcaagc acgggaccgg gggattgtcc attgacaagg agcatcttcc tggagaagcc
     5281 atcgggggcg tagtcctccc atgttatggt aaggtcaaac ttcttggtct tgaacgtagc
     5341 tgatacagat gtgatgaggg tttgtataag aagagggaga aagatcaagg aagaagttga
     5401 gaagtgcatc ttgactagca gcaagagaga tgttgactct cagtggctgg atacctcttc
     5461 atcgagcagg atcagcatgc tgtatataca acattcggaa actattacag caccgatatc
     5521 ttcgcagtga tgccttcatt cgactaaacc aagagtaact gcttacacga caacgaatac
     5581 cacgccgcat agcagcattc tgactactgt agctaattca gccaatcaag tatgtagatg
     5641 acaccgcaat tttatagcca actgtgcgta gtatctatct aggcacattt acccaataga
     5701 gtgtcatgcc ttgcgagatc gaatatgggg ttattcccgg ggcagtgctt ttttcgcata
     5761 tagggatcag cactaacatg acttgttgtt gggggctgag aaaacaagag ctggcagtgg
     5821 gtgattgggg gctgtacggg tcttggctga ggtcagacgt ttgctgatac ggcaaggccc
     5881 gagggtgatg atttaacttg gactatactt ttaagcatag ttggaaggag ttttcgttta
     5941 tataattagt gttttgaaga accgctacta tgctaagagc tatctaacta gtgaatcaac
     6001 gcagtggcta tatttcactc acttgtgttt cactgtttca ctgtttcact ggatgataac
     6061 atgcaatacc tccactaatg cctttcccca ttagcttatg ccttgggcag ataaacgtgt
     6121 ttactaaaca taaagcagtt agttgatatg tagttggtct tggtagggct tacatggctg
     6181 ctttgaggcc tggttttgtc atcttggcgg tcagcacaaa cggtcaagca actatggagt
     6241 accagtaatc ttggcaactg aaagcacatg gcacgaatgt tgtagattgg gatatgtaat
     6301 tacagaccgg attgtcaagt tatttgatcg tctatccaaa gcttggttgt cgtcctagct
     6361 agacttacat agcgcttgat agatactgtt cctggatttg aatgctactc tagggtgggg
     6421 ctgatggctt gataggatca agtcagcaga taaattggta tcgtgattat acacatgctt
     6481 gttcagactg catatgcgat tggccaatgt tggctttact ctgggtaaag cgggggctgt
     6541 tccattgtat cggtcttttt gagatgttca atcttgttat cttgtaacaa ataaagctgt
     6601 ctactaggat gcagttggta tggtaatagc actgttgtgc ctatacgcgt tcaagttcct
     6661 tgtagtcctc ccgacgcttc accaacctca aatcccttaa cccaagtgaa gaacctcgac
     6721 attgtttcca acaggatcga gaacaaacgc agcatagtac ccgggcctgt aattcctcgg
     6781 cccaggcttt ccattatcaa cagcaccagc tttcctgtat actcaatcag gaacatgtct
     6841 ttctttgttc agtacaagat acttacatag cagcctcatg ccactcatcg acatgcttcg
     6901 gattctcagc atcgaaggcg aaatgaacag gacacgttct gttctccata ttgccatcgt
     6961 atttcttaag agaactgccc ccgccgccaa gccaaaagtc aggacccttg ttcttttcgc
     7021 caaacgcaca gtagtatgcg cctgtaggtc cttgagcttc aaacttgaac tcgtagccca
     7081 gtggtgcgag gacggccttg tagaaatctc gcatctcgac gtagtgttcg ccgcagggga
     7141 gtgcaaagtg gctgagaccc attgttgctg ttgtgattga tgacctgtga gtgaatgttg
     7201 atgaattaaa gttgatgttg aacgggatat ctacagtctt atatagccat tgcttacaga
     7261 cgtcgaattc acggtaatac atgatatttc cccacttcgt cgtgaatcct ccccctcaca
     7321 tatcgtggcg ctcaccaaac cggactttgc tcaagtccgg aatctatccg attgcatatt
     7381 tctatgtacg acgatgcatg aatgcctaaa attgtcgcac aatccgtcag accatattca
     7441 cattgaccat tgaaacaaag gaacggataa atatgatgca gtctcgatga gaagctgaag
     7501 actttatgag gctggttggg ttcagcgggt agtagtttgg ctgcttacta tcccgaatag
     7561 gaaaatgaga tttttgatgg cgagctgaat caggtgatct ttacgatata ggaaaatgag
     7621 aataaatgcc caatgtttag tctggtgtga catgctgatt ataacaggga cgacatatca
     7681 tgaatgacgg gaattgtatt gccacccgaa atccgtccat caggcacgca cctcgggttc
     7741 cggaggctga cgacccggaa tcgatttgtg ttatcaggca agactctgca ttgtctatct
     7801 cctccttagt tgtagctgtg tacattgaca ttccatcacg acggagaaat tatccatggg
     7861 gtttgcaacc ctagctcgag attctcaatg tagccataac gccgaactct ttcgcatgcc
     7921 aagcatacgg gatctggaat acagtgtatt aaagactgaa cttctggaaa gaccaaatac
     7981 caaaggtatc ccttccaact agtcaaccac ggccgataac ctcggtatct tgtcgtggat
     8041 catgttgtcc atatactcat gaatgtgtta ctcattcgat cttagtagag atatgagctt
     8101 gacagtactc catgtactca tatgtatcgt cactcaatag caacgacaga ggaacaactg
     8161 agtagtcgat gctacggatc tcttgttccc ctgtcgtacc ggcccaaagg atgagacagt
     8221 tgagtgtttc caaactgggc gagtgtacgt aaacatattg catagcctcc accatcatat
     8281 cattgtcgac gaagcgagtg aaaagagtct acccgagtga aacctggtgt caaggactct
     8341 atcccagctt ctgaccctga ggtgtttgtt ggttggttct caagtctctg ctcgtaaaca
     8401 tcaccatgcc ggtctctggc ctgaatcaca tacaagggct ttcattgcaa ggcttgaaga
     8461 cgaagccgcg acgcgttgca actgcacttg actcgcgaca tagttgaagg gggtaggagg
     8521 atagtggcga agttgaaaat ggaagaacat cttatcttcg gggtcccctt caaggattgc
     8581 cgcgatgaca aagacgcgcg taatgtcttc ggggtcccct gtagagattt acgagatacc
     8641 gagaatgtga catttgcgga gggtcaaagt ttttatttga tctcttatct cgggtagaag
     8701 gcaatatgga ggaacttcct aagggagatg ttgagtctgt tacaatcatt aatgctattg
     8761 tgaaaataaa caactggcaa ggaactaaat tctagggtat ccccctgatt attccgtaca
     8821 gtaagataac catgataaca tagtaacata tccaacagag catacagtgg cataattatc
     8881 tagagaacat actctactta accggtacct gcaaatagta atttaaacta atagtcactt
     8941 agatatcaga cgccccaact tccatcttag agcactgtag gaaatcatct tcaaaggcag
     9001 ttgattgggg caagctgagt tcctgtagat taagctgaat gatcattgaa gtaattctcg
     9061 taaaacacaa gacgatatgt agtaagatcc tcgcagctgt gctaacatct atccgataca
     9121 agctaactcg gccgctagtt agatgatcga ctcccgaagt gcgtagatct atactaatca
     9181 aacccagaat tactacgtga caatatcatc aaaatacatt gcggctctgc caataatgta
     9241 tttgcaatat attgacagaa tcacgatgcc tcagtcgaaa cgacacaata cagatggcga
     9301 cactcagata cacctacatt ttagtcatca gttcatgttg tttcagttca ccatcgagtt
     9361 tgctgtatcg atcaaaaacg acagatggac gaggctaacc gtattgctat cacaatagtc
     9421 gccaagccga tatgcgagtt tcatcccaac acgatatccg taggaagaag caaaatggac
     9481 ccctaacata tgagcttttc cctagttccg atagccattc tgaccgctat ccgaatctta
     9541 tctattaggc ctatagggcc tgattgttat gttaggccag tcaggctact gaatgaggca
     9601 gaaagaggac cttttctatt tgaactggct aattgtgatt ctagtctagg tgtgcagatc
     9661 aggtttatcc ttgcaagaaa ctctataacc cactgcggat ctaaagtggc cagactactc
     9721 tgtagatgat aatatgattg tatatccttc aggcctacca gttctcgcaa tagagtttaa
     9781 cgaaatttat ctgccgttca gtagtctagc attccccctg tttgtcgtat ccatcgacaa
     9841 acgtcactcg cttagcttca gacttcatcg agactggact tatatacatt atagctttag
     9901 gttttaatat aaatactttg gttctcctaa ccggtttcat ttgaaagaca aagcattctc
     9961 actgacacac agacaatacc ctatacaacc catcgccatc atgcttgcta caccgaccct
    10021 gtccaacttc gacaaaccct ctcttccatc ctcggaggga ggtgatcccg cccttgcagc
    10081 tcgcttgcaa ccactgtatt cgaggtttct cacggatctt gatctacagc cggaatatag
    10141 acgtcacgaa agcgagaagc ttatggagga ggtgctcaaa tttgcgaaga gtactggtgt
    10201 acctcatgat ctcaactccc attcctatca aagtctcatg gttggataca catacgccga
    10261 tgtaagcttt ctttcccttg tatcgactgt ttcaagagct cacaccattt tcagaactgc
    10321 ctcccatatc atgacattga agtcaaggtt tatgtagcca tctacacatg gctggcaact
    10381 atttgcgatg acgccgaggc actaggcatc attgatgatg ttcaattgtt cgaacaacgc
    10441 tttattctcg gagaggaaca gcctacggta tgtttacttt atggttccaa ccccaagtct
    10501 caaaggcttc aatgtcaaca aaaagctaat caagatgctt aggtcctcct cagggctttt
    10561 gccgaccaac tcaaactcac ctataagctg taccaccccc ttgttgcgaa tctgattctt
    10621 tgctcctctc tgaatctgct cacttctaca tcccttgtgg ctcgcaaggg tattaaagaa
    10681 aagggtgatc atccatcaaa gggaggcaac tacttcgcct ggtatatccg ggaacgggat
    10741 ggcgtcggtg aagcctattc ctggttcact ttccccaaac gacaattccc caacctggac
    10801 attcctatcg aagctattga agatatgaca cgattcattg cctatctcaa tgatgtttta
    10861 tcgtgagtca gcctgtccta tttggtgagc tttcctattg acatatctat caggttttac
    10921 aaagagtccc tggctggcga gacacacaac tacatcaacc atacggctgc gtatgagggt
    10981 gttgattcgg atgctgcgct tcataaaact gctcaagaca ccatagactg tgcccgccgc
    11041 attgagagtg ttctcgcagg caagggcgag tatgagaaag cgtggcgact tcatgcatcc
    11101 ggatacctcc aaatgcacgt ccagagaggt cgttacaggc ttatagaggt gggcgttggt
    11161 gatgcgccag atgtgcatga agtcatcaag aagatttgaa ggctatgaca aaccagatct
    11221 gagtaacata ctaatcacat tagttgagcg aggagacaaa agcaggggga gaaggaggag
    11281 agtttcatta tatcatggta ggatcagggg ccaaatttga gtgggagatg atgtattggt
    11341 acttgtagcc agctgttact tgctcttggt ccggagtcaa gatacctgaa ctacctagct
    11401 ggcttcattt agcatattat attgagtccc attgcttcat ccgccatcat caatgtgatt
    11461 tcgattcaga gtgtattgtg aatcctaagg ccatgtatat gataccatga ggtctggaaa
    11521 tggttggatt cctatcacag tcctaatcaa agaacatcct ggttgtgctt tcagattccc
    11581 acaattcgat agctgtctga taaaaattcc gacccctcag tacagcatat gtattttcat
    11641 cgctgcccgg caatggcaaa gaaatagtgt cttttatcac ctctcctgag ctcgtttcgt
    11701 gcgtttctag gatgcagctg atcgtcttca aattgggcat gtgtgcgtga aggatctcca
    11761 taatgtccgg caagccatgt gatggtgatg gtggctgaca tttatattcg tagaaggccc
    11821 tccacccgat ttcgaaatga aggacttggt cccacccttg gattttgatg cgacttgtcg
    11881 ttatccggaa gtgtaggacg tcacggaagg tatcgatata tagcacatca gtatctggtg
    11941 tgaaccagac actgagttga tcgcgaagat gaaatgatgt ggtagacggt gtgagcgagg
    12001 gatcttgagg atggaagaga ggaagtttca agatcagatt ttttttatat aatggttggt
    12061 acgtgagatt aaggttacgt ttatgcccta ctttttgtga ctctcgatac aaggcaacct
    12121 ctttttttct tctttttttt tttaaaaaaa aaaaaaaaac ccgttgtata aaccatcaaa
    12181 taatggttgg tacaacttta aagacaattt taacttcggc tgccttctat caagagccat
    12241 acaaaggatg gcacgagaag attccttata ttaaggttca gatcaacctt tctatggctc
    12301 agacacgata ggtatcgatg ctcactgcca atgctatcat gaataacaag caggccgact
    12361 gggcattgcc atttcagcca acgtccgcag tggctactgt cgagtccgtg cctccaacat
    12421 gcctttcaag actccctgag gactatatag caaggggttg ggtttccatt gtgagcctat
    12481 gcttgcgctt cgtaaatata caatgtacta ttatgttgat ccggtaatag ataaagcctc
    12541 aactttccat cttccacacc aacatccatc gggttctgcg tcaccctgac tcccaactcg
    12601 ctctccatct cgatcggtac ttcagcaaga ggaatcatag tcttgacatc caccagggca
    12661 ataccaccga gattataccc gccgatggcc gccactccag agcagagcat aacactcttg
    12721 ccattgtaaa aaccactgta cccaagccat ttgcagtctt ggtagtcgat aaagtggctg
    12781 ggattctgca cgaccttttc tggggaagga gatgcgtcgc agcctgtttt ggcagttcga
    12841 agattccatg ttgatgctgt tcgcgaaccc cagttgaaag cagtgatgag attggcgcga
    12901 gtgtcatgga cgataccacc aagatggtcg ttgtagctga ggacaagctc tggaacaagt
    12961 gtcgttgggt ctgttcgata tacgtacgca gtactgtttg gacgatactg cgcaatggtt
    13021 ccccagatat actgaccatc atagtcaatc cctccattat gatactcatc gtctccctct
    13081 ttcgtaatag tcgcgtcagc gatcatatct ccctttccat tataaaccat caaatgcgac
    13141 aagcctgcac cagcacttct gtctgtcccg ttgatgatct ttccatactt tttcgtgggc
    13201 tctgtccaat gccctgaact aaccacatat cgatcatgac caagccgcac gatcccctcg
    13261 ggttcaaaag tgtctccttg aaaagtgatg ttttttatgc tcttccatat tgtagaacgg
    13321 ctgattttct ggaaagcatg tattatatct ggaccatcag atgctgcatg ggatggtggt
    13381 agtggagttg gagccagggg gtcatctttg tgaatagtga ggttgcgcgc catggccagc
    13441 gctggacaaa cagcgattga acttgtaagc ttcatatccg tcgttccaag attgagaaga
    13501 aaatagattt gtggtgcaaa gataaatatt gtcattagaa taaggagggg aagggctact
    13561 ttgaatgata tgctggaaca ccatggctgt cctgttgggg agccattgtc ttttagccgg
    13621 cggcgattgg tctgagactc catctcgagg catgctatca tcagaatgaa tgcgatgatg
    13681 atactgcagc tgtgagtatc ggcggtgatg gtgaatgata atggaacaag ttgaacctac
    13741 ccgatggctc ggccctgtca cgtggagact gtcgatccgg cagatgagat gaggcggcga
    13801 ttcttggggc tctccggggt tccggggctc cattttaccg gggggtcatt aaactctatg
    13861 gagaggtggt ggtattttta gattactcaa taacaacttc aatgcttgaa cgctacacgt
    13921 acaacgattc aagaatttct caatggcaag tctttggcat acattaatag tagagtaaca
    13981 ccgtatcaat actctttatg cgatgtctct gtagccgtgt gttcgttctg gctctcaagg
    14041 tttaagaaca atgagagtgt ttatggacaa cctaattcaa gctttgtgcg gtgatgaaca
    14101 ttattctgaa catacctata taaatgaaaa ctctgctacc attaaataaa atgtattccc
    14161 acatgaatgt ttaccatctg tgatacccat actcccaaaa tataaccaca aacacccaac
    14221 gatggcgcaa tggaagatca gaactcgttt cctggtcata tccgacaccc atagccaaga
    14281 attccccgac gaccgtagac ccttgcacaa agtcgacgta gccattcact gcggcgatct
    14341 aaccgaaaca tcaaagctcc acgaattcga gtccgccatc cgtcttctca aagacatcaa
    14401 cgctcctctc aaacttgtca taccaggaaa ccacgatttt accctcgata cgcccatatt
    14461 cagaagagca atcaccgaaa tacctccgcc cgacatcaat ctagtagaga aggaatatgg
    14521 acgatttgga gaagcaagac gcttgatgga gagttttaca cacgagggta ttgtgtattt
    14581 aacagagggt gttcatcatt ttgatctggc caatggtgct caccttgtgg tttacgctag
    14641 tccatatact ccttctgatg actgctgggg attccagttc gacccttgga taggtcacga
    14701 acgggaaata aacgagcaag tcgagatcat cataacacat ggtcctccaa aaagcatcct
    14761 cgatatgaac agtcgtggaa aacacatcgg ttgtccagaa ctcttcgacg ttgtcgctca
    14821 ggcgaaacct cttatgcact gcttcggtca cgctcatcga agctggggtg cagagttgat
    14881 caaatggaga gaccgcaact ctgaagaagc tatcgatatg gatgagtctg tcacgatcgg
    14941 ggttcttgat aggtttagtc ccaggagctg tgataagctc atggttgctt ggcagaagga
    15001 gaataagagg atgagtatgg aggatgcgag ggctataccc acgaaacatt gtgcaagaga
    15061 cgagttgccg attacgcgaa gggttcatac tctttttgtt aatgctgcta tgcaagggtc
    15121 gggtcacata cctttcaatt atccatggtt ggtagacctt gatcttccta taacttaaca
    15181 actaattcaa cttctcactc accgctacct tgcacgcata tcatgtaacc aacccgcagc
    15241 tatggtattt aatgcttagc aatgttgtcc tcgtgccgct tctaaacatc aacaccaaaa
    15301 cgcctcgtta gctcttcacc caacaccgca cccaaatcag gctgtgacca aaatcacaaa
    15361 caatcgagca taatagaaca gggaaaaaaa gagtcgatca tacacgtcat acgtacatat
    15421 cacctgcttc ccaccatttc caataactct caccaatcac gcctgcatcc gtgtgtccat
    15481 cagttggcct gttcttacga cccgcgaggc tttctggatg actaccaaca caatgtaacc
    15541 ctctgtctca gaatggattt tgcttttgat gatgaatttg gtcggccccc ggcttgaaaa
    15601 acgcctggag ggtttgtcgt gatggttgat gtggagatac agtcaggatc agagatatat
    15661 aaactgacag aattcttgca attttgttca gtcttcacca agatactttt ctctatattg
    15721 aaggatcgag tttagattca attgagaatt gttttattta tcgcggtccc caaaggtgtt
    15781 cccgagcttc cccaattcgc aacgccgtct acacccattc ggccattcgc aaccatggaa
    15841 cttttcagtc acgttatcat agaacgggat tttccagacg agagtaagtt gatcaattgc
    15901 ctatgctcaa cacgatcctt ctaacggcgg aaccagagat caagtccatc ttgaaccatt
    15961 cacaacaggc aactaggcat cagcaatacg tcccagatgc tttcgcccat caacctcaag
    16021 actattatca gagtccttct tcatcagccg aatctacaag ccgttttgat ccaagtcttt
    16081 atcaccaaga tcattccccg ctttggtcgc aaaactcccc aagcaactct tcctccacct
    16141 ctcccagctc tcagacctag tgtgagagtt cagcgcgtag ttatggtctc gaccagggat
    16201 cagaggatct acaagcggga ttggtgttgg acagtagcag ttcggaaggg gattctcttg
    16261 aatttcgaaa caaacatgca aacaagggta agtgttgcac ttttcccaat ggttcaacta
    16321 ggctaacaga tacaggggaa accacatgct gtgggaagtc atggaaagag ggcacgcact
    16381 acaagtaagt cacctcccag ttcttagcac ctctcctaac cacgtcaaca gcaaacacta
    16441 caatcgcgta cacaacctca gatacaaatg cgaaagctgc gcctttgcag gagcggacaa
    16501 gaaggaactc catcgccact attgggtatc ccacagagac tgggcggaag caaacaatat
    16561 tcctgacata agcgggaaat gcaaaggatg tgggaggact tttagaagaa aagatcgcat
    16621 tcgtctccat ctgaggcgct atccctcatg ccgtgaaaag ttagggcttt cagaacaaga
    16681 gtcctagctt tgcacgacac aaggggtgtc gtctgaggta gcgacgaatg cgatcttttg
    16741 gagttattgg tacttggtat cgtgttttgc atgtgaacgc ctgtttattc cctagcttgt
    16801 ttatctctct ctgtcttttg tcaatcgcaa atcttacact atgtatccca tgctctgatt
    16861 cctgagttct acaatggcca aattctctct ctgtgccaac tctagcattt cttgatacaa
    16921 acgactctcc aatccatcct gaacaaaatc caatggcaaa tccaacgatc atattaacaa
    16981 ctaccagtcg ctctcgggag tggtcttttc atcatcgctc cagtcgatgg gagagtccag
    17041 gctgcactcc cactcgcaca cctccagtgg cccaacgggc ttgaccgtct tggcaggttc
    17101 ggcacaattg acaagtttcg gaagctcctt cagatacttg accaaaaggt caggatggag
    17161 agcgatgcct tggagattct tctcaagctc ctctggaggg gaactgtcga tgatagcacg
    17221 aatcttggta gagctgggtg catccgcagt atgcttgctc aggtcgcttt tgaggaagcg
    17281 gacaatgcca tgaggcttgt cataaacctg catgcagacc caaatggcat ccagattctc
    17341 catggccttg gtgacggctt cgtcaatgac tgtcttactg ttagctggca tcttctctat
    17401 gtttgacggg agacgtacct gattctgggg atcccttgag cttggctcgg attcgctgct
    17461 cgatggaata gcgatcaaca ttgagcttct tccaaggggt acagcctcca atttgtcgga
    17521 gggtagatgg gtaacgaaag tcgacagcgc gcgagatgtc agtagtgacc gcatcagagc
    17581 agtcccaccc gcttgggaag tagccccgct ccgtatttat aatgtctggg ccttggagga
    17641 ccataaatgt caactccatg gcgtcgtttc ggaccgcgtt tgtgagacgg gtccgaaagg
    17701 cccgccaatc ttcagagccg tcgtacaccc aggcccagtc gacggggata ccgttgccac
    17761 accaaagctt gatgcgcttc tcttttggga ataccatatc gctgccgcgg cgttccatct
    17821 tacccttgac gctctcgtcg ctgcagggga cgatgatagc agcgaccaag ttgaggtcag
    17881 cacccgcatt cataaaggtg tgcttcaaga gattgaggtg gccttgatgg ggagggttaa
    17941 aggatcctgg atagagcagg atgtggttca cgcctcgggg tcgaagaagg gggggatctc
    18001 gagcggtacc attattgaat ggtcgatcag agaggtttga agacttgtag tcggcgggaa
    18061 taagccgctc gacatagtca gcgagtctcg gagatgacat gatgtattcg cgatggttac
    18121 tctgatggaa agttgtgtag aggtaaggag tgaagatatg gagaatggaa ggtaaggatg
    18181 ggtgagggaa gatgaggagg aaggagatga aaaaggaaga tataaactcg cagaagaata
    18241 gtatattagg gtcccactat tcaagcaaac aaacaaacgg tgattgcatt cacctggagt
    18301 gtgtaaacgc tggttgacgg tagctgtcgg agtgtgccag gtgcttgacg gatcgttggc
    18361 gctgttgagg gcgtgtaaga taaactcctc tgtctggtat cgaggaacga taaagagcaa
    18421 gtcttgagtc aaagatagct tgtaattttt cttttatatt ttatatatgt ttttactttt
    18481 caaacgtcta atattccaac agttgtagct attctgtaga tatgatacaa aaggggcttt
    18541 gttttgacac agcagtcggc atcaatggtc ggcaaaaaaa acagaacgac gtctttcatc
    18601 tagactcccc agattcatag taacaatgac attctagcac cttgcataca cgcgttgtgt
    18661 tttttcccga cttgttgtgc tgggtcgtgg tcgatatagg gaggtgagga agaccgttgg
    18721 cttcttggac agcatggaac aagtcggggc aactacaatc atgggcatgg cagaattatc
    18781 ggaaggcatc ctttattcat gtggttcttt gtataatatt gttgttttat ttattcaaga
    18841 ggctgtgttc ttctttatta cgttccaggc tatgatgttc tacattacct agtatgcgat
    18901 tatgcctacc caagtagctc gtgcctgtaa ctcgtccata ttgttcggaa atatcggacc
    18961 accgagatac gagaacatct agaaaaaagg cgggaaaaaa aagaaaaaaa aaagagcaaa
    19021 agtatatcgt tgcgtgtgta taccatgcat cttgccatgt cttggatatt tagtttacac
    19081 aacctgttga tattccgatc tgttgtaggg taagcacatg gcgaaatggt agggccgtcg
    19141 tgacacacat tccatgaacc ggtacatgaa cagggtacaa acaaacacaa cgcattacta
    19201 ataatagaaa tcatcaaaat tcagctttaa tcatgggtat tccaaaatta ccttgtatta
    19261 attatctata tgttatgctg atattcaccg acgctgatct cccaagcgcc ccatgctctg
    19321 agttgatcgt gattagcaca caaagtcaat aagcctcggc cgatcatgac agaaacggtc
    19381 gctgaaccct gtcggtatct gaatcaagta aagcacggag atggttcgtc gattcgaggg
    19441 aaaagccgca ggcacgagct gcatagatcg acacggcaca aaaacaccac gattgacggt
    19501 ctgagcacga catgaaatac gatgagaaac ggatgaatgc ataaaaatga gattttgcac
    19561 aacaagagct attttacatt gtttcagtta aatgttgggt tggctatcaa aagtgaatta
    19621 ctctgtggct tgcaaacaaa ctgtcatttc agtcggatca tgtctcagaa tccaaccaag
    19681 cggtgtaatt gaaagagaaa aagtaaaaaa aggtttgttc cgcacaagaa ggaagtatgt
    19741 attctgttgt accatattca gaacaggggg tagagaggta tggggtaacg tcacgtcacg
    19801 acaagtcatg ggagaagaat acaacatcaa aaagaaccca aagaacattt tctccattct
    19861 ctcaacgaca atgacaacac atgatgaccc ctgcttgtgg gatggcattt cactttgttc
    19921 ctattcgccc attagaccgc ggccacggca gacaaggctt ggggcgaact ggacctagtt
    19981 tagtgggaaa gctttttgtt ggagattttg gtttgggttt tgtctggctc tggcgtcatt
    20041 gtaatcatga cctgacttgt catggtggac tgtatgtgag ggctgttgct gttgagtatt
    20101 gacagagttg tgagatggag atgtcagttc aagatagaac caacatgatg gtacatcaaa
    20161 taaatgactt gtcgtaactt ccaacagctc ccccagtagc acagctgttc tagctccaac
    20221 cagctttagg tacctaccta agcttccgag tcagtcgttt ctgttggtcc ctaaccgtcc
    20281 ctgtctgtct gcatgtctgt ctgtctgtcc gttgagggga aggacaggac ggcgctaccc
    20341 ttttaaaccc aacatgcaaa agtcaaatgc tccttggttg aattggtcct catgggaaaa
    20401 acagggtctt tgaggactcc tccatcgtgt gtgtgtgtca ctcgctcatc catgtctcac
    20461 ttcccactta gcgcccaccg ctctgctttg ctttcccccc tcctctttta atccttgtca
    20521 tatctgcatt tttttttttt cattctccca tgatgcatac gtatcggtac agtgaggata
    20581 caagtttgat tcaggtgtaa cgagggacag aggaataata aatgcttctc ttgatcacgt
    20641 ctgtttacag ttgagatcgg tctgtattgt agtggtgata gtgattgtgg tatcgtttgt
    20701 taccatcttg aaatcctcca gtatcacggt ctctctgcac gtgtcgcatc cagtgtgtgg
    20761 cctgtccctt gccttgcgtt gccttgacct attgaatctg gcttgccgcc gcaccttttg
    20821 tcgtggtcgc ataatcacgg gtagatcaga gactgagtcg gagactgaat cgcagaaaag
    20881 gttatgcagt aaatcagacc agactgggat gtttgcattg cagatatcct ataacggtat
    20941 ctcaagcact ctgttctgtt ctcttctcta caactcccca actctatcca acacagccta
    21001 caacgcgttg tcacaaaccg atccgatctg actcgaccag tatccaatag tggaccagct
    21061 caagctgact ggcatttttc tctatagaga tttcctgggg gtggaaaaaa aaggcgaaaa
    21121 aggcttggga gtggatgccc ccatctcgtt ccttttggct tagttcaagt cgctggaacc
    21181 tgaagccgaa agggaattt
//
