LOCUS       BGC0002180             25173 bp    DNA     linear   PLN 27-FEB-2015
DEFINITION  TPA_asm: Aspergillus nidulans FGSC A4 chromosome VI.
ACCESSION   BGC0002180
VERSION     BGC0002180
KEYWORDS    .
SOURCE      Aspergillus nidulans FGSC A4
  ORGANISM  Aspergillus nidulans FGSC A4
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Nidulantes.
COMMENT     Aspergillus nidulans FGSC A4 CADRE,
            updated by Eurofungbase with contributions from
            CADRE (http://www.cadre-genomes.org.uk),
            AspGD (http://www.aspergillusgenome.org) and
            Ensembl Genomes (http://www.ensemblgenomes.org).
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:06:10
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25173
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[17176:24876]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      17177..24876
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..25173
                     /SMILES="C([*])C(-O)"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..25173
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002180"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25173
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            264..1011
                     /locus_tag="ANIA_11200"
                     /old_locus_tag="AN11200.4"
     mRNA            join(264..284,373..1011)
                     /locus_tag="ANIA_11200"
                     /note="transcript_id=CADANIAT00009370"
                     /old_locus_tag="AN11200.4"
     CDS             join(264..284,373..1011)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00009370"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00009370"
                     /db_xref="GOA:C8VJQ9"
                     /db_xref="UniProtKB/TrEMBL:C8VJQ9"
                     /locus_tag="ANIA_11200"
                     /note="transcript_id=CADANIAT00009370"
                     /old_locus_tag="AN11200.4"
                     /product="conserved hypothetical protein"
                     /protein_id="CBF82290.1"
                     /transl_table=11
                     /translation="MFSSTRRAEGPCATELTQVSSLLPPRGPYEFSLLPTLTRPLEDLS
                     KCIEGARQTSATANGYSPTGLVPLADSILEICQAACTAYGLVDGAIAAGVGTGSSDNSP
                     TATGIGAAGLTGDRPSSSGASTWRCVKTPMTLGSLTLQNEEESLLARQIVYAVLTSLSA
                     LLREVYVREKDVVSETDVVGEGGVGAGAALYGREGAGAVSQCLSRVLALLGKIVPE"
     gene            1254..3095
                     /locus_tag="ANIA_11192"
                     /old_locus_tag="AN11192.4"
     mRNA            join(1254..1461,1522..2347,2397..2481,2540..3095)
                     /locus_tag="ANIA_11192"
                     /note="transcript_id=CADANIAT00009371"
                     /old_locus_tag="AN11192.4"
     CDS             join(1288..1461,1522..2347,2397..2481,2540..3095)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00009371"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00009371"
                     /db_xref="GOA:C8VJR0"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002401"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="UniProtKB/TrEMBL:C8VJR0"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 207; E-value: 8.4e-63)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ANIA_11192"
                     /note="transcript_id=CADANIAT00009371"
                     /old_locus_tag="AN11192.4"
                     /product="cytochrome P450, putative (Eurofung)"
                     /protein_id="CBF82292.1"
                     /sec_met_domain="p450 (E-value: 1.5e-77, bitscore: 250.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMAALDVFNVPYSVPLLGSTVVILIGFIAIKALRVGSRPKGLPP
                     GPPTEFIWGNTKQIDLFYPQYQYRKWAQQYGPVYTVMLGDTAHVVVSGLRDVRDIFIKQ
                     GASSQNRPPSRFQLLMRDGFFPGLNNGEKWRQSRRMWQAVLNNSAAKQYLPYQELETRQ
                     LLFDLLRAPTEWRDHIERYSNSVAMTMVNGRRIIDAADPRVKETIQDLYDLAETGVRGA
                     FLDSWPFLWKLPEWMFPVCRQARKIAAKHREYIWRNYSDVAKRTSQGEVLPSVNHAIQE
                     KLKQGWPGVSEIEGAEIGHHLLTGTTDTTASTLINWVAAMCLHPEAQKKAQEEIDRVVG
                     PNRLPTDADAANLPYVQQVIQEAQRWITAVPLSLPRAANAPVHWGKYTIPEETGLIMNS
                     HALHNDPDIFPEPDKFKPERWEGKPNASSNGDAQLLFTFGAGRRVCPGQHLAERSLFLV
                     ISHWLWGFDTLQATDDDKNKIPIDKDDLRPGFIVCLNPFPAKITPRTAQHRELIERIWK
                     EELEVSLDESQQWKATPEGIARLLERVGK"
     gene            complement(3143..6500)
                     /locus_tag="ANIA_09221"
                     /old_locus_tag="AN9221.4"
     mRNA            complement(join(3143..4683,4795..4999,5418..6060,
                     6121..6500))
                     /locus_tag="ANIA_09221"
                     /note="transcript_id=CADANIAT00009372"
                     /old_locus_tag="AN9221.4"
     CDS             complement(join(3443..4683,4795..4999,5418..6060,
                     6121..6500))
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00009372"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00009372"
                     /db_xref="GOA:Q5AR59"
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR002409"
                     /db_xref="UniProtKB/TrEMBL:Q5AR59"
                     /locus_tag="ANIA_09221"
                     /note="transcript_id=CADANIAT00009372"
                     /old_locus_tag="AN9221.4"
                     /product="Putative Zn(II)2Cys6 transcription factor,
                     putative (Eurofung)"
                     /protein_id="CBF82293.1"
                     /transl_table=11
                     /translation="MTRQIPLLALSWLELIFFSCYYGGLAGLGYHSLWRIALRRRNVAP
                     AIKSVLQTGRFADGTPLTRRYTNLEFLDKKLVPAVIFYDGLLTGACPLYRLLLVDIHST
                     MQAMALCMLVSTRSKSLSTISLLLPTFWNVFNQFYGAAFVYPLYLLLEAVTTGFNPLYP
                     VETETSRSALLVSAMIGSFLPFTFLWPAFLRSGTESRQRAIALYRFAPVVFSLLQIVGE
                     KVLGAQMIPQPTSQASPYLVAGCAATVGHWYALGGALGLAMRLSHRKGRLGALTLVLKR
                     LYLPRSAEETTRLDASVLARAAHEFLQYDVLVLIAAYIPYAYYLLAPLNLASPFAMVVS
                     LIAFRGPDPSGLNLHLRHGSERLTPSPESLELVAYIIMHFREVDKEARVCLLILFIHLK
                     TSHWMSGASGTRTVLIMSTVNQSSTRSELAGNWERLRKSCDTCQEAKVKCSQHKPSCHR
                     CLRHRQPCVYSPQRRSGRPPKRPSPSSRLGPESNNSGDDIHNENTIQRTNLNANDSAMT
                     DAGAVDPRVLTGDFAASTGIDPVDDIFQTSFESFLAASLSPKGGLLPGSHSNPTTPNGF
                     SMNSPSITDPFGAFPFLITDHNLPIAALSSHVPPIDQLPVLSTGASNTSSECGDCGAKC
                     YSSLLQHLLFLRQTLPESTRPSIDVIMQAEGHVRALLDRVLGCNACLGNRSSILLISAI
                     TERIVQMLDWIIEEKTLLDTENMRYNRRTFSSWGRPPRLPPHGLNGMRRNVCHVSLRVG
                     NTELDEDAKQYFLKNFILLRLKKLAVKVQEVRRTATTRPGDCIYRAAELVLADSIQRLD
                     YLRGQCQLWE"
     gene            complement(8183..9712)
                     /locus_tag="ANIA_09220"
                     /old_locus_tag="AN9220.4"
     mRNA            complement(join(8183..8284,8422..8522,8571..9154,
                     9213..9712))
                     /locus_tag="ANIA_09220"
                     /note="transcript_id=CADANIAT00009373"
                     /old_locus_tag="AN9220.4"
     CDS             complement(join(8183..8284,8422..8522,8571..9154,
                     9213..9712))
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00009373"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00009373"
                     /db_xref="GOA:Q5AR60"
                     /db_xref="UniProtKB/TrEMBL:Q5AR60"
                     /locus_tag="ANIA_09220"
                     /note="transcript_id=CADANIAT00009373"
                     /old_locus_tag="AN9220.4"
                     /product="toxin biosynthesis protein (GliH), putative
                     (AFU_orthologue; AFUA_5G10320)"
                     /protein_id="CBF82295.1"
                     /transl_table=11
                     /translation="MADYVIQNLTSNLQAMQYAYSSREEMPVWATKLLTPIFMAVAVLT
                     TLPPPGPLRVIVGLTAFTSLWLHVLTHWVSGPAFFMDAIFMISITVRWLLMFVAGTPEI
                     DYHQTTQSGTTITHKGTKDSSTLRQGLTKLRWSVELWSCWRGQGWNFVDQHLPRGAERT
                     QSRWEFLVSNAGRVLLNQYISDLVRKYAFCALWPAQVDAHVDFSSLPLLNRHGLVALQL
                     IRDSLMLDSEYRKASILFVGLHLSTPDRWPSLFGNMRDLYTVRNFWGRVWHQIFRQIFT
                     RCGDIVANALNAQKGTLLYKYSRLYVGFLVSGVQHYACALLIPSAEYGWGMFWQMPAYA
                     AVVTVEDILKYYGREAGIQDGNFVRFLGYIWTAYWMTLIYALPVGFVSDIGGFTGDGNF
                     QLSDPCVSCSSTSIPVSGFESIDLEFGLW"
     gene            10385..12125
                     /locus_tag="ANIA_09219"
                     /old_locus_tag="AN9219.4"
     mRNA            join(10385..11807,11887..12125)
                     /locus_tag="ANIA_09219"
                     /note="transcript_id=CADANIAT00009374"
                     /old_locus_tag="AN9219.4"
     CDS             join(10385..11807,11887..12125)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00009374"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00009374"
                     /db_xref="GOA:Q5AR61"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="UniProtKB/TrEMBL:Q5AR61"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 296.2; E-value:
                     5.4e-90)"
                     /gene_kind="transport"
                     /locus_tag="ANIA_09219"
                     /note="transcript_id=CADANIAT00009374"
                     /old_locus_tag="AN9219.4"
                     /product="MFS transporter, putative (AFU_orthologue;
                     AFUA_5G10340)"
                     /protein_id="CBF82297.1"
                     /transl_table=11
                     /translation="MSSDDTVKQEHSCSADSEKQDSSCASDNEQPKEPQSPRNIHGLLW
                     VVTILAIYSSTFLFALDNTIVANIQPAIISSLNGIEKLAWSGVAFVMASSATVLTWLQI
                     FNQFNIKWMYIFSIAVFMGGSAICGAAQSMDMLIGGRVICGIGGVGQYVGVMNFLPRLT
                     TMQERPMYVSAMGLTWGAGTVLGPIIGGAFTDSSAGWRWSFYINLVVGGLFAPVYIFLL
                     PSLEPQPAGTTVSSRLKRMDLVGTLILFAAFAAGVIGINFAGAMYPWSEPGIIVAITLG
                     GVLFIVFGIQQTYCILTTEETRLFPVELVSWRQPLLSLLFVCGCCTGVCVTVPTYVIPL
                     YFQFTEGDESLQSGVRLLPFVCLLVFSCVSGGYLAGRLGYYIPWYIMGGGFCLIGSALM
                     YTIKPSSGPGATYGYSSLIGLGSGMYLQLGHAVAQAKVKPEKVPAAVAFTTTAQLNGLT
                     FALVLSQCVFVNEAAKRIGWILPHEPRSTIVDAISGTGSTFVQELPTATQNEVLGAIVT
                     AIDRTYILCIVAAAVTLLATLGMKWERLFIEAAAAA"
     gene            complement(12438..14170)
                     /locus_tag="ANIA_09218"
                     /old_locus_tag="AN9218.4"
     mRNA            complement(join(12438..13267,13339..14170))
                     /locus_tag="ANIA_09218"
                     /note="transcript_id=CADANIAT00009375"
                     /old_locus_tag="AN9218.4"
     CDS             complement(join(12438..13267,13339..14170))
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00009375"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00009375"
                     /db_xref="GOA:Q5AR62"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002401"
                     /db_xref="UniProtKB/TrEMBL:Q5AR62"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 332.1; E-value:
                     9.9e-101)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ANIA_09218"
                     /note="transcript_id=CADANIAT00009375"
                     /old_locus_tag="AN9218.4"
                     /product="cytochrome P450, putative (Eurofung)"
                     /protein_id="CBF82299.1"
                     /sec_met_domain="p450 (E-value: 7.7e-73, bitscore: 234.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVQTFYLIGEKERSTRELDVGDPKTVNALRQGLAEVFNILSAEG
                     IDFHDCHGPISTIESILRSESVGITVNGHPVRYPQQPQGIPIFGNHFEIYPDHLGNHER
                     LFNKYGSVIRTNNMGRVTYLTNDPDIAALAFRDNDYFTKAPSSASHPLYGIRDQTALFL
                     CDTESPAWKEAHKFIPPSMTPRAVRHYTPLLQQSVDTVFNVLDKFDNNGQAFNVYHLTA
                     KLASQVICQLVLGVDLHHFDAVDSPVHPIIVLLQRYLTLNRRVQTKGAWYSYLPFGDPV
                     ALKNTRRELYGLIEEAVITCQKKNGGTTGDLPIQTAALHATCLVDYLARATDEHGNKLR
                     HEYILSNTLALVGAGFVTSSAFLSWLIYSLVEYPGQQDRLLQELVDHGAVSDKRWTYDE
                     IQALPFLDAFVKEAQRMHSPSFQPARNVKKDIILPGGWALPQGSILIPSIPHLHHHTAY
                     WENPDRFDPDRWRTEKVKNRHRSVYVPFAAGPRSCIGFNVALQEVKISLAELVYRYEFV
                     NATNEGIEYDPDFIVIRPVNFYVRAIRRTEWPARSP"
     gene            14357..15762
                     /locus_tag="ANIA_11198"
                     /old_locus_tag="AN11198.4"
     mRNA            join(14357..14441,14489..15762)
                     /locus_tag="ANIA_11198"
                     /note="transcript_id=CADANIAT00009376"
                     /old_locus_tag="AN11198.4"
     CDS             join(14357..14441,14489..15762)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00009376"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00009376"
                     /db_xref="GOA:C8VJR5"
                     /db_xref="InterPro:IPR001199"
                     /db_xref="InterPro:IPR001433"
                     /db_xref="InterPro:IPR001834"
                     /db_xref="InterPro:IPR008333"
                     /db_xref="InterPro:IPR017927"
                     /db_xref="InterPro:IPR017938"
                     /db_xref="UniProtKB/TrEMBL:C8VJR5"
                     /gene_functions="other (smcogs) SMCOG1094:ferredoxin
                     (Score: 104.7; E-value: 8.2e-32)"
                     /gene_kind="other"
                     /locus_tag="ANIA_11198"
                     /note="transcript_id=CADANIAT00009376"
                     /old_locus_tag="AN11198.4"
                     /product="conserved hypothetical protein"
                     /protein_id="CBF82301.1"
                     /transl_table=11
                     /translation="MASPASITLAEVARHSSPNDLWIVIEGNVYDVAEYREDHPGGDEI
                     LRQFAGKDATTEFQDAGHSNDAYVKLKTLLVGSLQSKTLPENQPEESSRIVSIAVSDRG
                     KIPTKRQARNGNDTSKYGQLPSLVLAGGLALLFFTLKQHPWQSIQGYLSQAQVSRVQSS
                     GWVGFLGGFLTATTLNTAAATFVGLTAKKTLLLRHRELEEYPRVKQHYLPLPPKKPGIS
                     GENTQQFLTLVDRQCIAPNVYKVRLQGDGLVIGLGQHLKVLAEIDGRKIQRSYTPVSPV
                     GNSPKVDLIIKVYPKGQLGNYLLNLPLQSRVEIRGPFGRYSPSPTWKHIACIAGGTGIA
                     PIYQVMRAWPGEITLLYGNETWEDILLREELEQLVLQSPRRIKVHHVLGQPKSDWKGLR
                     GWITREMIQDLLPEPSSSTGFLVCGPDGMVRAIRGHFEAIDANGEEKANVFVF"
     gene            15866..16769
                     /locus_tag="ANIA_11199"
                     /old_locus_tag="AN11199.4"
     mRNA            join(15866..16007,16057..16769)
                     /locus_tag="ANIA_11199"
                     /note="transcript_id=CADANIAT00009377"
                     /old_locus_tag="AN11199.4"
     CDS             join(15866..16007,16057..16769)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00009377"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00009377"
                     /db_xref="GOA:C8VJR6"
                     /db_xref="InterPro:IPR005645"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="UniProtKB/TrEMBL:C8VJR6"
                     /locus_tag="ANIA_11199"
                     /note="transcript_id=CADANIAT00009377"
                     /old_locus_tag="AN11199.4"
                     /product="conserved hypothetical protein"
                     /protein_id="CBF82302.1"
                     /transl_table=11
                     /translation="MPKILCLHGYGTSASILQHQLGPFMAAADPSYEFVFLEGEIECQK
                     AQGLGPFVKGPFLCYNESFAPADIQESCDLIDEMIQAAGPFDGIIGFSQGGSVALSYLL
                     QRQIDGHPPPFRWAVFFSTVIAFAPNDTFGSNILANLTDHEIRLLDGYPATDLSSLHPL
                     TRALCETTAQTFYSAKTGGFISPNTPIAEFSKRDDPSQPRVFHPALLGDRIPIPTVHIT
                     GRKDNSLMVGLSVLVQGLCDQRLIRSLTHSGGHNVPRSADDVRAAWAAVDWAIQHSQKQ
                     HIW"
     gene            17177..24876
                     /locus_tag="ANIA_11191"
                     /old_locus_tag="AN11191.4"
     mRNA            join(17177..17488,17560..17704,17762..18030,18083..23869,
                     23929..24610,24695..24876)
                     /locus_tag="ANIA_11191"
                     /note="transcript_id=CADANIAT00009378"
                     /old_locus_tag="AN11191.4"
     CDS             join(17177..17488,17560..17704,17762..18030,18083..23869,
                     23929..24610,24695..24876)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (50-474). E-value:
                     2.8e-173. Score: 568.5. Matches aSDomain:
                     nrpspksdomains_ANIA_11191_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (608-931). E-value: 2.6e-98.
                     Score: 320.9. Matches aSDomain:
                     nrpspksdomains_ANIA_11191_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (1000-1177). E-value: 1.4e-24.
                     Score: 79.1. Matches aSDomain:
                     nrpspksdomains_ANIA_11191_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1742-2046). E-value: 4e-53.
                     Score: 172.4. Matches aSDomain:
                     nrpspksdomains_ANIA_11191_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2078-2256). E-value: 9.9e-55.
                     Score: 177.1. Matches aSDomain:
                     nrpspksdomains_ANIA_11191_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2358-2436). E-value: 2.3e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_ANIA_11191_PKS_PP.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:CADANIAG00009378"
                     /db_xref="EnsemblGenomes-Tr:CADANIAT00009378"
                     /db_xref="GOA:C8VJR7"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016038"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR018201"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="InterPro:IPR020807"
                     /db_xref="InterPro:IPR020841"
                     /db_xref="InterPro:IPR020842"
                     /db_xref="UniProtKB/TrEMBL:C8VJR7"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 252.4; E-value:
                     1.4e-76)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ANIA_11191"
                     /note="transcript_id=CADANIAT00009378"
                     /old_locus_tag="AN11191.4"
                     /product="polyketide synthase, putative (JCVI)"
                     /protein_id="CBF82304.1"
                     /sec_met_domain="itr_KS (E-value: 2.5e-177, bitscore:
                     579.1, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.2e-99, bitscore: 320.9,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.6e-50, bitscore:
                     160.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLPGEIHHRFTYMYIAQVSFADLDITKHNLPISTMSSSDSPNYG
                     DATMPIAIVGMAARFSGEATNPSKLWDMMVQGRTGHSAVPENRFDAEAWHHPSHERRGT
                     IQPRSGFFLREDPAVFDAPFFSMTAKEAAGMDPMQRKLLEISYEAFENAGIPITKLPGT
                     ATGVYSGVMTNDYELMTAGDPMQLPQNAASGTSRAMLANRISWFYDLRGPSFALDTACS
                     SSLYALHLACQSLQAGETDQALVTGVNLILAPNFISQLSSMHMLSPDGKSHSFDSRANG
                     YARGEALAAVVVKPLYQALADGDTIRAVIRGSGANQDGKTVGITIPNPQAQAELIRKTY
                     ATAGLGLEQTGYFEAHGTGTPVGDPIELSAIGTSFGEHRSQNCPLFVGSVKTNVGHTEG
                     AAGLAGVVKTVLALEAGIIPPLADFQELNEKLRLEEWKLALPLKATPWPMPGLRRASVN
                     SFGFGGANAHVILDDAYHYLKSHGLSANHHTTLSESEDSSDSGLEMDSSTSDSGEGQSS
                     KLLLFSAYDGAGIKRTEASWNSHLADILADSKTVDETMGMNDLAYTLSDRRTTFDFRSF
                     AVASSVQDLKAKLENDGLPRLNRASRRSNPVFVFTGQGAQWPAMGRELLSNPIFRASIE
                     RSKAVLELEGCEWDVVQVLSDPQDQRIHIPAFSQPVCTILQVALVDLLQSWGIQPAATV
                     GHSSGEVAAAYAAKMISQDEAVRIGYWRGFYSEQVKARLENIRGSMMAVGLSESQATSY
                     LNRVPEGSVVVACINSPSSVTLSGEDHSIKTLEAILQADGHFARKLRVEVAYHSPHMKT
                     VADEFLNAVGIITPQPSEIPMFSSVTETRVEDPATLVASYWMQNLISPVRFSGALATLL
                     NDTPSVKANTRRRRTAGIVWSALIEVGPHEALKGPCRQIMSGLNTKLADQIPYMSVLSR
                     GKSAVETSLTAAGLLWASGHPINIREVNQYRDTGERVITDLPPYPWNHEKGFWHEPAAS
                     ISARLRKEPRNDLLGVPVAQQNPFERCWQNYLSVSECPWQKDHVITGTVLYPGAGHLIM
                     AFEAAIRLAADNRPLKGVSFSDVHFDKGLVIPSDDHGVETRLCTRPHESLLDWYHYTLY
                     SINATGDWTKHSWGSFSLHYEDAVSVQQAKRSKGEYDDINTRACRKLDVESFYEQLLSI
                     GTEYGPTFRNLVHAAAAPGYHSGVGTITIPDTKSVMPHEFEYPHLIHPATLDAIFHLIF
                     VAMGEGNALSESAIPTRVDRIYISTDLPRGVGAKYTGYGRAEPVSSRDTLGTIVVSDEN
                     WSAGPKIIVEGMTVTEVSAGASTSFNSLLIPGGQGRIATLEWKEDVDSLVGPTAESWLA
                     QKGPSIGGQASDVTEAVQRLDAWLELSCFKSTDLGTLVICPSKLKGSFELVKKYGSKHG
                     ERYRFGRTTIIEFSENDISAAESAFAPHGIESSYAAIDLSATPEHAMEQLGMFDLIIAE
                     ENVIVQFPDVTKILHREGRVAIIRSHALPDERHFAATKGLLKEISFESQDGSILQIAGL
                     GLEMDPAIRSLDDVVLLQHVDASPAAKNFEKRLTAQLTSLGAHVRSNTIANASSLSGNI
                     VISLLEIDCQFVISWTSEEFEQFRQLTNARYVLWITRGGLLDADRASLDYAPSTGLLRT
                     VRVEKPQIRLPHLDLSPSLDLNSDRAVEIVISAFHSSIKPSVKEKNLEMEYAESNGLLY
                     IPRARGHAALDHELALRGEKVSSIPGPLSAPGIARRLETSLAGSPSQARWVPDETVGDK
                     LADFDVEIQVSHVGLEHSKVENYLNGKQLSLAPGLGRVAVGTLTRAGAKVSRFIPGDQV
                     FALHAAPFHTHLRVTEDAVHAVPDILSPAQAAHLPLAAARAWHSLIDVAAFRAGQSVFV
                     NGASDTVGRLTVELARLLKGDVFASVSSDDEKHTLTKTYNIPEDHIFSLSHRTDWASDL
                     KAAMGQGQLDIVINNATPSPAIRSLFQSIAPKGRFVDLTQRLDPSLLDPRMFQRNVTLS
                     LVDWESLTNPQLGALMVRSLDLLRAGALTPIKEEYIFSVSDLPEALLSVGQQQHERVAA
                     PVVVEFSADATVPLLPSLPAPLHLKPDATYILAGGLGALGLTIAENMCSHGAGHLVFLS
                     RSGASSQRQQEALESFRARGCKVDVVKCDVTDQEQVQALATQIREQSWNVRGIIQLAMV
                     LRDSIFENMTFDKWETAVNPKIKGTWNLHAELPKDVDFFIILSSLSGIIGNTAQANYCA
                     GNTYEDALAHYRRKQGLAATTLNVGLVTDASHFNENSTIEDYLRKYSHWIAAQVTDSEL
                     QHTITAVMRRTVGDKNEPVPDQLLVGLSDNVRRDGNSLNLWPQDRKFDHRISLEDGLGV
                     VEKDTNQQKLKASTTVAQAHEVVETALRLNVAAAMTASPDDIDIEKPLYAFGIDSLKGI
                     EVRNWIFSELQADVSVFEVLSPMTLSRLALKIVSKSTLVGAELAAEAAADSVA"
     aSDomain        join(17327..17488,17560..17704,17762..18030,18083..18778)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_11191_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.80E-173"
                     /label="ANIA_11191_PKS_KS.1"
                     /locus_tag="ANIA_11191"
                     /protein_end="474"
                     /protein_start="50"
                     /score="568.5"
                     /tool="antismash"
                     /translation="IAIVGMAARFSGEATNPSKLWDMMVQGRTGHSAVPENRFDAEAWH
                     HPSHERRGTIQPRSGFFLREDPAVFDAPFFSMTAKEAAGMDPMQRKLLEISYEAFENAG
                     IPITKLPGTATGVYSGVMTNDYELMTAGDPMQLPQNAASGTSRAMLANRISWFYDLRGP
                     SFALDTACSSSLYALHLACQSLQAGETDQALVTGVNLILAPNFISQLSSMHMLSPDGKS
                     HSFDSRANGYARGEALAAVVVKPLYQALADGDTIRAVIRGSGANQDGKTVGITIPNPQA
                     QAELIRKTYATAGLGLEQTGYFEAHGTGTPVGDPIELSAIGTSFGEHRSQNCPLFVGSV
                     KTNVGHTEGAAGLAGVVKTVLALEAGIIPPLADFQELNEKLRLEEWKLALPLKATPWPM
                     PGLRRASVNSFGFGGANAHVILDDA"
     aSModule        17327..24807
                     /complete
                     /domains="nrpspksdomains_ANIA_11191_PKS_KS.1"
                     /domains="nrpspksdomains_ANIA_11191_PKS_AT.1"
                     /domains="nrpspksdomains_ANIA_11191_PKS_DH.1"
                     /domains="nrpspksdomains_ANIA_11191_PKS_ER.1"
                     /domains="nrpspksdomains_ANIA_11191_PKS_KR.1"
                     /domains="nrpspksdomains_ANIA_11191_PKS_PP.1"
                     /iterative
                     /locus_tags="ANIA_11191"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       17938..17985
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_11191_0001"
                     /evalue="8.00E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="ANIA_11191"
                     /protein_end="227"
                     /protein_start="211"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GPSFALDTACSSSLYA"
     CDS_motif       18179..18217
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_11191_0002"
                     /evalue="2.30E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="ANIA_11191"
                     /protein_end="287"
                     /protein_start="274"
                     /score="11.2"
                     /tool="antismash"
                     /translation="FDSRANGYARGEA"
     CDS_motif       18410..18457
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_11191_0003"
                     /evalue="3.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ANIA_11191"
                     /protein_end="367"
                     /protein_start="351"
                     /score="12.8"
                     /tool="antismash"
                     /translation="YFEAHGTGTPVGDPIE"
     CDS_motif       18518..18562
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_11191_0004"
                     /evalue="1.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ANIA_11191"
                     /protein_end="402"
                     /protein_start="387"
                     /score="11.2"
                     /tool="antismash"
                     /translation="GSVKTNVGHTEGAAG"
     CDS_motif       19175..19231
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_11191_0005"
                     /evalue="3.10E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ANIA_11191"
                     /protein_end="625"
                     /protein_start="606"
                     /score="22.5"
                     /tool="antismash"
                     /translation="VFVFTGQGAQWPAMGRELL"
     aSDomain        19181..20149
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_11191_PKS_AT.1"
                     /evalue="2.60E-98"
                     /label="ANIA_11191_PKS_AT.1"
                     /locus_tag="ANIA_11191"
                     /protein_end="931"
                     /protein_start="608"
                     /score="320.9"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWPAMGRELLSNPIFRASIERSKAVLELEGCEWDVVQV
                     LSDPQDQRIHIPAFSQPVCTILQVALVDLLQSWGIQPAATVGHSSGEVAAAYAAKMISQ
                     DEAVRIGYWRGFYSEQVKARLENIRGSMMAVGLSESQATSYLNRVPEGSVVVACINSPS
                     SVTLSGEDHSIKTLEAILQADGHFARKLRVEVAYHSPHMKTVADEFLNAVGIITPQPSE
                     IPMFSSVTETRVEDPATLVASYWMQNLISPVRFSGALATLLNDTPSVKANTRRRRTAGI
                     VWSALIEVGPHEALKGPCRQIMSGLNTKLADQIPYMSVLSRG"
     CDS_motif       19415..19510
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_11191_0006"
                     /evalue="3.30E-09"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="ANIA_11191"
                     /protein_end="718"
                     /protein_start="686"
                     /score="29.3"
                     /tool="antismash"
                     /translation="GIQPAATVGHSSGEVAAAYAAKMISQDEAVRI"
     CDS_motif       19904..19945
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_11191_0007"
                     /evalue="4.20E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="ANIA_11191"
                     /protein_end="863"
                     /protein_start="849"
                     /score="12.8"
                     /tool="antismash"
                     /translation="ASYWMQNLISPVRF"
     aSDomain        20357..20887
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_11191_PKS_DH.1"
                     /evalue="1.40E-24"
                     /label="ANIA_11191_PKS_DH.1"
                     /locus_tag="ANIA_11191"
                     /protein_end="1177"
                     /protein_start="1000"
                     /score="79.1"
                     /tool="antismash"
                     /translation="DLLGVPVAQQNPFERCWQNYLSVSECPWQKDHVITGTVLYPGAGH
                     LIMAFEAAIRLAADNRPLKGVSFSDVHFDKGLVIPSDDHGVETRLCTRPHESLLDWYHY
                     TLYSINATGDWTKHSWGSFSLHYEDAVSVQQAKRSKGEYDDINTRACRKLDVESFYEQL
                     LSIGTEYGPTFRNL"
     CDS_motif       20438..20515
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_11191_0008"
                     /evalue="6.50E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="ANIA_11191"
                     /protein_end="1053"
                     /protein_start="1027"
                     /score="31.5"
                     /tool="antismash"
                     /translation="WQKDHVITGTVLYPGAGHLIMAFEAA"
     aSDomain        22583..23494
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_11191_PKS_ER.1"
                     /evalue="4.00E-53"
                     /label="ANIA_11191_PKS_ER.1"
                     /locus_tag="ANIA_11191"
                     /protein_end="2046"
                     /protein_start="1742"
                     /score="172.4"
                     /tool="antismash"
                     /translation="SQARWVPDETVGDKLADFDVEIQVSHVGLEHSKVENYLNGKQLSL
                     APGLGRVAVGTLTRAGAKVSRFIPGDQVFALHAAPFHTHLRVTEDAVHAVPDILSPAQA
                     AHLPLAAARAWHSLIDVAAFRAGQSVFVNGASDTVGRLTVELARLLKGDVFASVSSDDE
                     KHTLTKTYNIPEDHIFSLSHRTDWASDLKAAMGQGQLDIVINNATPSPAIRSLFQSIAP
                     KGRFVDLTQRLDPSLLDPRMFQRNVTLSLVDWESLTNPQLGALMVRSLDLLRAGALTPI
                     KEEYIFSVSDLPEALLSVGQQQH"
     aSDomain        join(23591..23869,23929..24183)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_11191_PKS_KR.1"
                     /evalue="9.90E-55"
                     /label="ANIA_11191_PKS_KR.1"
                     /locus_tag="ANIA_11191"
                     /protein_end="2256"
                     /protein_start="2078"
                     /score="177.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="ATYILAGGLGALGLTIAENMCSHGAGHLVFLSRSGASSQRQQEAL
                     ESFRARGCKVDVVKCDVTDQEQVQALATQIREQSWNVRGIIQLAMVLRDSIFENMTFDK
                     WETAVNPKIKGTWNLHAELPKDVDFFIILSSLSGIIGNTAQANYCAGNTYEDALAHYRR
                     KQGLAATTLNVGLVT"
     CDS_motif       23594..23692
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_11191_0009"
                     /evalue="5.00E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="ANIA_11191"
                     /protein_end="2112"
                     /protein_start="2079"
                     /score="44.8"
                     /tool="antismash"
                     /translation="TYILAGGLGALGLTIAENMCSHGAGHLVFLSRS"
     CDS_motif       24028..24138
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ANIA_11191_0010"
                     /evalue="9.50E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="ANIA_11191"
                     /protein_end="2241"
                     /protein_start="2204"
                     /score="63.2"
                     /tool="antismash"
                     /translation="VDFFIILSSLSGIIGNTAQANYCAGNTYEDALAHYRR"
     aSDomain        join(24490..24610,24695..24807)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ANIA_11191_PKS_PP.1"
                     /evalue="2.30E-10"
                     /label="ANIA_11191_PKS_PP.1"
                     /locus_tag="ANIA_11191"
                     /protein_end="2436"
                     /protein_start="2358"
                     /score="32.6"
                     /tool="antismash"
                     /translation="STTVAQAHEVVETALRLNVAAAMTASPDDIDIEKPLYAFGIDSLK
                     GIEVRNWIFSELQADVSVFEVLSPMTLSRLALK"
ORIGIN
        1 gaagagttta aactagcaga ccatggtcaa ttgccaggtg ccaaaactag tcttgactag
       61 gtaaatgatt gagatgcttg atttgttgag ttaagcaggg ctgtgtgcaa aaggaggggt
      121 tcatgaatgt agtgcagtga ggggtcgact actgggcagt tagccgcaat tctcagcttt
      181 ccatcacacc accacagaac ttaccttgca gtcgaggcag catagacaac gacctccaac
      241 agctctccaa tcagcagaga ccaatgttct caagtacccg gcgggtaagt aactctttcc
      301 atcatctggc ccatcttctt ttcttttttg ttttcaattg taagctctcg actaacgacg
      361 cccggcacct aggcagaagg cccctgtgca accgaactga cgcaggtatc atcgctgcta
      421 cctccgcgcg ggccatacga gttcagcctc ctgccaacac tcactcgacc gttagaggac
      481 ctctcgaaat gcatcgaagg tgcgagacag acctctgcga ctgcaaatgg ttacagcccc
      541 acagggctcg tcccgctagc ggattcgatt ctggaaatct gtcaggctgc ttgtacagct
      601 tatggtcttg ttgacggtgc tattgctgca ggtgtgggta caggaagcag tgataatagc
      661 cctactgcca caggaatagg agcagcagga cttacaggag accgcccctc ctcttccggc
      721 gcatcgacct ggcgctgtgt aaaaaccccc atgacgctgg gatcgcttac gctacagaat
      781 gaagaagagt cgctgctcgc aaggcagatc gtgtacgccg tgttgacaag cttgagcgca
      841 ttactgcgag aagtttatgt tcgagagaag gacgttgttt cagagactga tgtggtgggg
      901 gaaggagggg taggagctgg agcggcactg tatgggcgtg aaggggctgg agccgttagt
      961 cagtgtctct cgagggtttt agcgctcttg ggaaagatag tacctgagtg attctacttt
     1021 gttgatcttt cacaattcca atttcctagt ttgttgctgg catttggcta ctaggcaccc
     1081 tctaccccga taggctagga tatcctgatc ccggtgttga gcggaaacct cccggccccg
     1141 atatgcagac tcgtcgggag atttcaagca aacccagaga gcaattacaa atcagtcggg
     1201 accagaaaca gacgtgctca tagtgataga tagacatatc aagccatgaa taggtgtttt
     1261 gaggttacca caattgacat cctgatcatg acaatggcag ccctcgacgt cttcaacgtt
     1321 ccatactctg tgcctctctt aggaagcacc gtcgttatac tgatcggctt cattgccatc
     1381 aaagctctac gtgttggttc acgcccgaag gggctgccac ctggaccgcc gaccgagttc
     1441 atctggggca atacgaaaca ggtacattct tcaagggtgt gcgagggtgc agatttacgg
     1501 ccaaataact aacgccggca gattgacctg ttttacccgc aatatcagta caggaagtgg
     1561 gcgcagcaat atgggcccgt ctatacagtc atgctaggcg atacggcgca cgtcgttgtc
     1621 agcgggctgc gcgacgtgag agacattttc atcaagcagg gagcaagttc ccagaatcgt
     1681 ccgccctctc gattccagtt gctcatgcgc gacggcttct tccccggctt aaacaacgga
     1741 gagaagtggc gacagtcgcg cagaatgtgg caggccgtgc tcaacaacag tgcggcgaaa
     1801 cagtacttac cgtatcaaga gctagagact cgccagctcc tttttgatct tctcagggcg
     1861 ccgacggagt ggagagacca cattgagcgc tacagtaaca gtgtggccat gacaatggtt
     1921 aatggcagga gaattattga tgccgcggac ccccgtgtga aggagaccat tcaggatctg
     1981 tatgacttgg ccgagacagg cgtgcgcggt gcatttctgg attcctggcc attcttgtgg
     2041 aagctgccgg aatggatgtt ccctgtttgc aggcaggccc gcaagatcgc cgcaaagcat
     2101 cgtgagtaca tctggaggaa ttattccgat gttgcaaagc ggacaagtca gggagaggtg
     2161 ctcccttcgg tcaaccatgc gatacaagaa aaactcaagc aaggctggcc aggggtttca
     2221 gagatcgagg gtgcggaaat tggccatcac ttgctgacag gcacaaccga cactaccgca
     2281 tctaccctga tcaactgggt cgcggcgatg tgtctgcatc ctgaagcaca aaaaaaagct
     2341 caggaaggta ggtctttttc cgccactcaa aattacgcca cagactgacc attcagaaat
     2401 cgaccgtgtt gttgggccga atcggctacc caccgacgcg gacgcggcga atcttcctta
     2461 cgtccaacag gtaatccaag agtgagtgta aacgtccagt tgtcatttcc acatattccc
     2521 tagatctgat tcccactagg gcccagcgtt ggatcactgc agttccacta tcgctccccc
     2581 gcgctgccaa cgcacccgta cattggggaa agtacaccat tcccgaagaa actggactga
     2641 taatgaactc gcacgccctc cacaacgacc ctgacatttt tccagaacca gacaagttta
     2701 aaccggagcg atgggaggga aagcccaatg ccagctccaa cggagatgca cagcttcttt
     2761 tcactttcgg agccggtcgt cgagtctgtc ccgggcagca ccttgcagaa aggagtttgt
     2821 ttcttgtcat ctcgcattgg ctctgggggt ttgacacact acaagcgaca gatgatgata
     2881 aaaataaaat ccccattgac aaggacgatt tgagaccggg attcatcgtg tgtctcaacc
     2941 catttccagc gaagataacg cctcgcacgg ctcagcatcg cgaattgatt gaaagaattt
     3001 ggaaggaaga attggaagtc tcacttgacg agagtcagca gtggaaggcg actccggagg
     3061 gtattgcgag acttctggag agagttggga agtgatcatg gtatcaagca aacaattgcg
     3121 accgctgcac tgaacacggc aatacagcat gaacttaagg ccattgagag gtgaatctag
     3181 agctgactga atgagcaact gctacccaat ggcgtccccg gatgaactga aagtaatccg
     3241 aacatcgctt cctttgatag tctgagacgt atttagaaac tgttccaaat gagaaaagat
     3301 aagacatttg atggttagca atggctgaac ccaagtcaat atgcagagtt tatatattcc
     3361 gagcagggat atcacactat aagcttcaat caggggaatc cggtcataac ctcataagtt
     3421 cagagcataa aatcgctaca tctcactccc ataactgaca ctggccacga agataatcca
     3481 gtcgttgaat cgaatccgcc agcaccaatt ccgcagcgcg gtatatgcaa tcgccaggac
     3541 gggtggtagc tgtccgtcgc acttcctgca ccttaactgc gagtttcttt agtcgaagca
     3601 aaatgaaatt cttaagaaaa tactgtttgg cgtcctcatc caattcagta ttacccacgc
     3661 gaagtgaaac gtggcagacg ttcctccgca taccattaag gccatgaggt ggtaaccggg
     3721 gagggcgacc ccatgaacta aacgttcgtc ggttgtaacg catattctcg gtatccaaaa
     3781 gagtcttctc ctcgatgatc cagtctaaca tctggactat gcgctctgtt atcgctgata
     3841 tgagcaggat agacgaccga ttgccaaggc atgcgttgca gcctaatacc cgatcaagta
     3901 aagcacgcac atggccctca gcctgcatta tcacgtctat tgatggcctg gtggactcgg
     3961 ggagcgtctg gcggaggaac aaaaggtgct gtaatagtga gctgtagcac ttcgcaccgc
     4021 agtcgccgca ctcgctgctt gtatttgagg ctccggtgct tagtacgggt agctgatcaa
     4081 ttggaggaac atgcgatgag agcgcggcga taggcaagtt gtggtccgtt atgagaaacg
     4141 gaaaggcgcc gaatggatca gtgatggagg gcgaattcat cgagaagccg ttgggtgtgg
     4201 ttggattgct atgagatcct ggcaggagtc cacctttagg agacaatgag gctgcgagga
     4261 aggattcaaa ggatgtttgg aagatatcgt cgacaggatc tatgccagta cttgcggcga
     4321 agtcgccggt tagcacccgg ggatcgactg ccccggcgtc agtcatggca gagtcattgg
     4381 catttagatt cgttcgctgt atggtgtttt cattgtgaat gtcatctccg gaattgtttg
     4441 attcaggtcc taagcgactg gagggactgg gcctcttggg aggacgtccc gaccgacgtt
     4501 gcgggctgta gacgcagggc tgacgatgtc gaaggcatcg gtggcaggac ggcttgtgtt
     4561 gactgcattt gaccttggcc tcctgacagg tatcgcagga cttgcgcagg cgttcccagt
     4621 taccggctag ctctgaacgc gtggaagatt ggttcaccgt gctcatgatg agaactgtcc
     4681 ttgcttgagg aggattgcgt gttaatgatg gaggggacag ttcagttcag tttgcattgt
     4741 ttgcttggtt tgccttgttt gcgactgagg ctgaggagtg gctcaagttc ttactgcctg
     4801 aagcaccgga catccagtgc gaggtcttca aatgtatgaa cagtataagc aaacaaactc
     4861 tggcttcctt atctacttct ctgaagtgca tgataatata ggctaccaac tcgagacttt
     4921 ctgggctcgg cgtaagccgt tcgctgccat gcctcagatg cagattgaga ccgctaggat
     4981 cgggacccct gaacgcgatc tgcaggattg atggtgataa tgttgcattg gagaatgaaa
     5041 ggcatggcca gccgcgttgg cttcgccgaa ctgcagaagg atcacatagg ctaacgagac
     5101 aagctaacgc cagtagatac tttcaccagg gccctcctac taatctttct ggattcggct
     5161 atgtcgcatt gctgcgcgtt gcccaaatgt gtcctcacaa gggcttggcg tggcgaacag
     5221 cggccgatac aactttgcat gacttagtgg cttgcaaagg tacttggctt agtcggccga
     5281 ggtccagaat cacataatca caaacgaatc ggcttcggtt tgcttcaagt tgcctaatct
     5341 gagatagcta gatgccagcg aacccggtac gcgaaagcca gaaccgcccc cggccctaaa
     5401 aaaatggtgc caagtacaag ggacacaacc atcgcaaagg gcgatgccag attgaggggc
     5461 gcgagcagat agtatgcgta cggaatataa gctgcaatga gcacgaggac atcgtattgc
     5521 agaaattcgt gcgctgcgcg agcgagtaca gaggcgtcca agcgagtagt ttcttcagcc
     5581 gagcgaggca gataaagccg tttgaggact aaggtgagag cccccaagcg gccctttctg
     5641 tgagacagcc gcatggcgag acctaaagct cccccaagag cgtaccaatg ccccactgtg
     5701 gcagcgcagc cggcaaccaa ataagggcta gcctgagaag ttggctgagg gatcatctgc
     5761 gcgcccagca ccttctctcc aacaatctgc agaagtgaga acactaccgg agcaaatcgg
     5821 tataatgcaa tagcacgttg tcggctctcc gtgccagacc gaagaaaagc tggccagaga
     5881 aaggtgaacg gtaaaaaaga gccgatcata gcgctcacca gtaacgcaga acgagatgtc
     5941 tcggtctcga ccggatacag agggttaaag ccagtcgtta ctgcctctaa taagaggtag
     6001 agggggtaga cgaaggcagc accgtaaaac tggttgaaga cattccaaaa agttggcaag
     6061 ctgtccctcg gtagattatt agagcttcgt tatactcaaa ggcagaagga cccgactcac
     6121 agcaaagata tagtcgataa cgacttggat ctggtgctga caagcatgca gagtgccatc
     6181 gcttgcatgg tcgaatggat gtccaccagt aacaagcgat aaagtgggca tgctccagtc
     6241 aacaatccgt cgtagaagat taccgcagga accaatttct tatccaaaaa ttccaagtta
     6301 gtataccggc gcgttagggg cgttccatcc gcaaagcgcc cagtctgcag aacagacttg
     6361 atagcgggtg ccacattcct tcggcgaagt gcaatcctcc agagggaatg gtatcccagt
     6421 cccgctagtc cgccgtagta gcagctgaag aaaatcaatt caagccacga tagcgctagg
     6481 agcgggattt gccgcgtcat attgtgacga aaggaaatgc aaaacagtgt acgcaaacag
     6541 tgagaggaag taagaaaaag tagagactca gtagttacat atatggctca tctatttgct
     6601 ttttatcaat tcgtttctac ccgaattccg cctctctaga tgaaaagcac ttcgatgtcg
     6661 gcaagaaact atgaatgcag aagccccgtg gaccctagtt cgggtagttt tgctggcaaa
     6721 cagcgatgaa aattactatt ctgcttacgc cattactccg agtgataact aaatccttcc
     6781 cgctgcagag cacacaaccc acattaggca cgcaaggctc cgtagtaggt acatctacct
     6841 actttagata tgcggcactt ccggttgctt ccgaacagaa agaccgatcc cttttggttt
     6901 cggcagtaca ctcttcgaga atcacattga tcaatgtgat gagcttcgag aatatttggt
     6961 aatcaaacaa taatcgtcaa ggcgctttga tatctggcac ctctccagta aaacccttta
     7021 tgatagaacc tgcctcctat tagctttctt tcttagagca ggtagtttgc taattattat
     7081 gcaatacagt cttttctaca gaaaacgggc ctaatattga actcattgct ggccgttacc
     7141 acccatagta gacgtattgc cttatgaagg aggattggca accatgcgag gtcattccag
     7201 ggtatccaca gcttgattgt tacacagcag caatctacca tcagggttct actgacagtc
     7261 cattaagcag tcaagatgcg tgtctgtcga aaacgttcgg ctgtcaggtg acgccacccc
     7321 gtggtatgcc cctacctcta gtgaccttgg ttcccgtgca tcgaccacat tcagacctgc
     7381 ctctcctgta cactaaacat agtccaataa actcgggcta actcaactat cgagcggaaa
     7441 ggagggaaat tcacatatag agacccactg atctacctcc attacttaat cgagcagaaa
     7501 gttacaagga ccccaaacca gacttggtgt agctcatagt gcttgctgat ttaagttttg
     7561 aggcaaaaag cttaaaaatc acttgaaaat gaaaattagc acagcagaca tgtatacctt
     7621 gacaagcctg cgatattaag tcctcacggg tttgtcaagg tccacctgag acgtgtcata
     7681 tccgaaggca cggcgatggt ggtatcagta gaagtaaaca tccgttcgca acatgatctg
     7741 aataacaatc caagaagaat agcattaaag gtcggctggg gcatagcagc tccaacggaa
     7801 tcaacctgtt ccgcataagc tcacacttga tattccattc aacatgcggt tgatgaaaaa
     7861 tttgactgcg tcatgtcgag caagattggt tatagctgga ctgctacttg ctttcaatta
     7921 cagactatgg ctcttttctc taagacaact gtcacatctc tggtgttcat gtaaaccata
     7981 acaaaacccg cgacggtcga atgtcagaat acgagttggg tcgatggtca ggaaccgcac
     8041 gggatttttg gtaaaccagt ggttacccgc gaagaactta tattacataa aatccccaag
     8101 ttagttaggc tatattcact gcataaggtt gctgattcat tagatagttg atttatacgg
     8161 catgtttgta ctgtttgtca atctaccaaa gaccgaactc caggtctatg ctctcaaagc
     8221 ccgataccgg tatactagta gaactgcatg aaacacaagg atcgctcagc tgaaagttac
     8281 catcctctta cacagtatag gtttgcactt agataatcca gctgaccctg aatacgtaat
     8341 gcataaacac aattggtaat gcacatattc ctagtagttg actatatatt tttgcccact
     8401 ccaccatcag gcagcacata cgccagtgaa ccctccaatg tcggacacaa agccaacagg
     8461 cagagcatag ataagcgtca tccaataagc tgtccaaata taaccgagaa aacgaacaaa
     8521 gtctgtgccc gaaattagac aggaacatac cgacagcgag gtgaacttac tgccgtcttg
     8581 aatacccgcc tctctgccgt aatacttaag aatatcctcg acggtgacga ctgccgcata
     8641 ggctggcatc tgccaaaaca tcccccagcc atattcagcg gatggaatca gtaatgcgca
     8701 ggcatagtgc tggactcccg ataccagaaa ccccacataa agcctgctgt acttataaag
     8761 taatgtccct ttctgcgcat taagagcatt ggcgacaata tcgccacacc tcgtaaagat
     8821 ctgtcggaaa atctgatgcc agacgcgtcc ccagaaattg cgcactgtgt agagatcgcg
     8881 catattgccg aagaggctgg gccagcgatc gggtgttgat agatggagtc ccacgaagag
     8941 tattgaagcc tttcggtatt cgctgtccag catcagacta tcacgaatta actgcagagc
     9001 cacgagtccg tgtctgttga gcagaggaag ggaactgaag tcgacatggg cgtcgacctg
     9061 agcgggccag agtgcacaga atgcgtactt tcggaccagg tctgagatgt attggttcaa
     9121 caggactctt cctgcattgg aaacaaggaa ctccctgaac gtagagagtc agcacgtcat
     9181 ccgtcacgaa aacggggagc aacagttcat accagcgtga ctgtgttcgt tcggcgcccc
     9241 gtggaaggtg ctggtccacg aaattccacc cctggccccg ccagcacgac cagagctcca
     9301 cgctccacct caatttagtc aacccttgac gaagagtact gctatccttt gtgcccttat
     9361 gagtgatcgt tgtgccggat tgggtagtct ggtgatagtc gatctcaggt gtccctgcca
     9421 cgaacatgag aagccagcgc acggtgatcg agatcataaa tatggcatcc ataaagaacg
     9481 caggtccgga gacccaatga gtcaggacat gaagccatag actagtgaaa gctgtaagcc
     9541 cgacaatgac gcgtagagga cccgggggag gcagagtggt taggacagcg accgccatga
     9601 aaataggggt gagaagtttc gtagcccaaa caggcatctc ctcacgagat gagtacgcat
     9661 actgcatggc ttggagattg ctagtgaggt tctgaattac atagtctgcc atagtgccct
     9721 aactctgagc gagctgtgag atgtatacct gcgatttcgg tttgaagaag cagcaaaaac
     9781 aacatatgta ggcaggctgg tagcaccaca ggcatcctta ttttgatctt ttgatagaat
     9841 atactagagg ataaaacaga gaggcgtatt tggagtggaa gggaaagccc ttgagatagc
     9901 tcgggtggtt tgtttgtcag catcggcaat agctcgggag gttttcgtgc aatttcaggt
     9961 gcgaaaagaa ggctcagcaa atcaaaagca tgctagaagc tagttgaacg attggtactg
    10021 aagctagatt ccagaactct gaaaaatgta gatcactgta gcaatgtctc cgatagacat
    10081 tatggtgcag gtgatctttc agttgcgggt tgtgcccagc cctaacctcc cggcaaccac
    10141 ccgatggagg aaaaaccttc agaatcatgt agctcatctc aagtttcgcc atgaatgatt
    10201 tcaaatcgtg attgctaatc aattctctcc gggagggaca acgttggccc gccttgaatg
    10261 tcttaagggg gtttgtatag gttgctgaaa ccactgtctc tttcctgact tctcgtcgtt
    10321 agttccaagt ttcgggcaac gccatcgaat cctcttcgaa tctcttcggc attttctgga
    10381 taccatgtca tcagatgata cagtaaagca agagcacagc tgctctgctg atagcgagaa
    10441 acaggacagc agctgcgcgt ctgataacga gcaaccgaaa gaaccccaga gccctcgcaa
    10501 catacacggc ctgttatggg ttgtcactat tctggccatc tacagttcca cgtttctgtt
    10561 tgctcttgac aacactatcg tcgccaacat ccaacccgct atcatatctt cccttaatgg
    10621 catcgagaag ctcgcctggt ccggtgtcgc ctttgtgatg gcatccagtg ccacagtcct
    10681 gacatggctt cagatcttca atcagttcaa cattaagtgg atgtacatat tctccattgc
    10741 agtgttcatg ggaggctcgg ccatctgtgg tgcagctcag tcgatggata tgctgattgg
    10801 aggtcgtgtc atctgcggca tcggcggtgt tggtcagtac gtcggcgtga tgaacttcct
    10861 cccacgcctg acgacgatgc aagagcgtcc catgtacgtg agtgcgatgg gtttgacgtg
    10921 gggtgcaggg acagtactgg gcccgatcat cggcggcgcc ttcaccgata gctcagcagg
    10981 atggcgatgg tcattctaca tcaacctcgt tgttggtggc ctctttgcgc cagtttacat
    11041 attcctcctc ccatcgctag agccacagcc cgcgggaaca accgtgtcca gtcgcctgaa
    11101 gcgtatggat ttagtgggaa cgctcattct ctttgccgcc tttgctgcgg gagtcattgg
    11161 cataaacttc gcaggtgcaa tgtatccctg gagcgaaccg ggtattatag tcgcgatcac
    11221 ccttggcgga gtcctcttca ttgtgttcgg aatccaacag acatactgca tcctcacgac
    11281 ggaggagacc cgactcttcc ctgtggaact tgtttcgtgg cgccaacctc ttctctcgct
    11341 gcttttcgtc tgcggctgct gtactggtgt ttgcgtgacg gttccgacat atgtgatccc
    11401 actgtacttt cagttcactg aaggcgacga atcgcttcaa tccggcgtcc gactccttcc
    11461 gttcgtctgt cttctggtct tcagctgcgt ctctggtggc tatcttgcag gccgtctggg
    11521 ttactatatt ccgtggtaca tcatgggcgg tgggttctgc ctgatagggt ccgctctcat
    11581 gtataccatc aagcccagca gcggtcctgg agccacctat gggtacagct cgctgattgg
    11641 gttggggtct ggcatgtacc ttcaactagg ccatgcggta gcgcaagcca aagtcaagcc
    11701 ggagaaagtc ccggcagccg tggcatttac cacaacggcg cagctgaacg gactaacgtt
    11761 tgcgcttgta ctgtcgcaat gtgtcttcgt aaacgaggca gcgaagcgtg agtatctcct
    11821 actgctgaat tccttcagcc attaccgtag tcgtggcaat tataagctaa tatcctttaa
    11881 ctataggcat cggctggatc ctccctcatg aaccacgttc gacgattgtg gacgcgatct
    11941 caggaaccgg gtcaactttt gtgcaggagt tgccaacagc tacacaaaat gaagttctcg
    12001 gtgcaattgt aaccgccatt gatcggacat atatcctctg catagttgca gctgctgtga
    12061 ccttgctcgc gactttagga atgaaatggg agcgtctatt catcgaggct gccgctgcag
    12121 cctagcagcc ttaacggtct gctgcattct tgcaaatcct gtagtaaaat ttcgatgggt
    12181 gcggactgaa ctagctcggc ttaaacgcat attgtggtgt ctgggtgtgg atttttagct
    12241 tgtggttaca tccttgataa ccttaagaaa tgttcttttc aaggtgatat tgccaatgga
    12301 tcaatattgg ctactacaat gtactgttat tttaatctgt aataattgtg tttatttgtg
    12361 cgaggtgctg aaaatatcaa gaccagaacc tagccgcaac gtagatctac ttacagtcga
    12421 gaaaaatgta ggcagcctca gggagaacga gccggccatt ccgtccgccg aatggcccga
    12481 acgtagaaat tcaccgggcg aatcacgata aagtccggat catactctat cccctcgttg
    12541 gtggcgttca caaactcgta gcggtagaca agctcagcca aggatatctt tacttcctgc
    12601 aacgccacgt tgaatccgat acagctgcgc ggaccagctg caaatggcac atacacgctt
    12661 cggtgccgat tcttgacttt ctccgtccgc caccggtcgg ggtcgaagcg gtccggattc
    12721 tcccagtatg ccgtgtggtg gtggaggtga ggaatactcg ggatgagaat tgaaccctgc
    12781 ggcagagccc atccgcccgg aaggatgatg tccttcttga cgtttcgagc aggctggaaa
    12841 gatggactat gcatgcgttg tgcttccttg acgaaggcgt ccagaaaggg tagggcttgg
    12901 atctcgtcgt acgtccatcg tttatcagag acggcgccgt gatcaaccaa ttcttggagg
    12961 agccggtctt gctgaccggg gtattcgaca agggagtata tgagccaaga gaggaaagca
    13021 gagctagtca caaagccggc accgactaga gcgagcgtgt tgctgagaat gtactcatgg
    13081 cgtagcttgt ttccatgttc atccgttgcc cgcgccaggt agtctacgag acaggttgca
    13141 tgtagcgcag ccgtctgtat aggaaggtcg ccagttgtgc caccgttttt cttttggcac
    13201 gttatgacgg cctcctcgat gagaccgtat aattcccttc gagtgttttt aagggcgacg
    13261 gggtctcctg ttgatatatt caatacagtc tcagcaacgg caaaccagga aacccatgtt
    13321 caggaactag gaacataccg aatggtagat aggaatacca tgctcccttt gtttgtacgc
    13381 ggcgattgag cgtaaggtag cgttgaagga gcacaatgat aggatgtacc ggactgtcga
    13441 cggcgtcgaa atgatgaaga tcgactccaa gcaccagctg gcagatcact tgggaagcta
    13501 gttttgctgt taagtgatag acattgaatg cctgtccgtt gttatcgaat ttatccagca
    13561 cgttaaatac ggtgtctacc gactgctgaa gtagaggagt gtagtgccga acggctcgag
    13621 gggtcatgct ggggggaata aacttgtgtg cctctttcca cgccggggat tcggtatcac
    13681 atagaaacag cgctgtctgg tccctgattc cgtaaagcgg atgactcgct gacgatggtg
    13741 ctttggtgaa gtagtcattg tccctgaacg caagtgctgc aatgtctggg tcgtttgtga
    13801 ggtatgtcac tctgcccata ttattagtcc ggataacgga accatatttg ttgaagaggc
    13861 gttcgtgatt tcctagatga tctggataga tctcaaagtg gtttccaaat atagggatcc
    13921 cttggggctg ctgaggatag cgtacgggat gcccgttgac agttataccg actgattcac
    13981 ttcgcaaaat actctcgata gtacttattg ggccatgaca atcatgaaag tcgattcctt
    14041 ctgcactcaa tatattgaag acttctgcta gtccctgtcg aagcgcgttc actgtctttg
    14101 gatcaccaac atcgagctcg cgtgtcgagc gttccttttc accaataagg tagaatgtct
    14161 ggactgtcat attgaacgag ttcggatcat gggctttgtg aatcaactcg aagatcgtcc
    14221 aaatatcatt ataacgcaat tgtgctcggt cagttttgtg aacttcccga acctcccgta
    14281 agacgctcct attttatacc ttacggattt ctattggcct tgcttgagga acaaacctgc
    14341 atctttgcgc gatatcatgg catctccggc tagcattact ttggccgaag tcgcgcggca
    14401 cagcagtccg aatgacctct ggattgtgat agagggaaac ggtaagaacc gttcagcgca
    14461 gaaggactca actaacgaaa tggaatagtc tatgatgtag cagaatatcg tgaggaccat
    14521 cccgggggtg atgaaattct ccgccaattt gctggaaagg atgccacgac agagtttcaa
    14581 gacgccggcc actcgaatga cgcctacgtg aaactgaaga cgttgctcgt cggtagtctg
    14641 caatcgaaaa ccctaccgga aaatcaaccc gaagaaagtt cacgtatcgt ttcaattgcc
    14701 gtaagcgata gaggcaaaat tccgaccaaa cgacaggcaa ggaatggaaa tgacacgtca
    14761 aagtatggcc agctgcctag cctagtgctc gcgggagggc tagcattgtt gttctttaca
    14821 ctaaagcaac acccctggca atctattcag ggctatcttt cgcaagccca agtttcacga
    14881 gttcagtcga gcggatgggt agggtttctc ggcggattcc tgactgccac aacattaaac
    14941 actgctgccg caacttttgt cggcttgaca gccaaaaaga ctcttttgct acgacaccgc
    15001 gagctggagg agtatccgcg agtaaagcag cattacctgc cgcttcctcc aaagaaaccc
    15061 ggtatcagcg gtgaaaacac ccagcagttt ctgacactag tggatcgcca atgcatcgcc
    15121 cccaatgtgt acaaggtgcg gctccagggc gacggattgg tgattggact agggcagcat
    15181 ctcaaagtat tggccgagat agacggaaga aaaatccagc gaagctacac cccagtctcc
    15241 cccgttggga attcgcctaa agtggattta atcatcaagg tctaccccaa gggccaacta
    15301 ggcaattatc ttctcaatct cccgctccaa tcgcgggtgg agatacgcgg tccgtttggt
    15361 agatattccc cgagcccgac gtggaagcat atcgcatgca ttgcaggggg taccggaatt
    15421 gccccgatat accaggtaat gcgggcatgg cctggagaaa ttaccctcct ctatggaaat
    15481 gaaacatggg aggacatcct tttgcgggag gagctggagc aactggtcct tcagtcaccc
    15541 agaagaatta aagtgcacca cgttctgggt caaccaaagt cggactggaa gggccttagg
    15601 ggctggataa cgagagagat gattcaggac ttactgccgg aaccatcctc aagcactggg
    15661 ttcttggttt gcggacctga cgggatggtg cgggcaattc ggggacattt tgaggctatt
    15721 gatgcgaatg gcgaggagaa ggccaatgtg ttcgttttct agactaggct aggcggtcta
    15781 tataagaact tgatagtttt caaggcaaag ttcaacaaat ctgtcctcct ttaacattct
    15841 ttttctaagt gtcgactcta ccatcatgcc caagatactt tgcttacacg gatacgggac
    15901 atctgcctcg atcctccagc atcagctggg ccccttcatg gcagctgctg atcccagtta
    15961 tgagttcgtc ttcctggaag gagagataga atgccaaaag gcccaaggtc cgtacccttg
    16021 tcagagcaag gtcacatcca agtaacgaga ttgcaggact ggggcccttc gtgaaggggc
    16081 cattcctatg ctacaacgag agcttcgcgc cagctgacat ccaggagtcc tgcgacctta
    16141 tcgacgagat gatacaagca gccggcccgt tcgacgggat aatcggcttt agccagggcg
    16201 gctcggtcgc cctttcgtat ctgctccaac gccagatcga cggacacccc cctccctttc
    16261 ggtgggccgt gtttttctct acggtgatcg catttgctcc caatgacacc tttggtagca
    16321 acatacttgc caatcttacg gaccacgaga tccgtctgtt ggatgggtat cctgctacgg
    16381 atctctcgtc gcttcatccg ctgacccgag ccctatgcga gacaactgcg cagactttct
    16441 actctgccaa aaccgggggg tttatctccc ctaatacccc aatcgcggag ttctctaagc
    16501 gggatgatcc ctctcagccg cgagtcttcc acccagcctt gttgggggac cggattccta
    16561 ttccgactgt gcatattacc ggccggaagg acaatagctt gatggtgggt ctctctgtcc
    16621 ttgtacaggg cctatgtgat cagcgtctga tacgatcctt gactcattcc ggtggccaca
    16681 atgtcccccg gtctgcggat gatgtccgtg ctgcatgggc tgctgtggat tgggctatcc
    16741 aacatagtca gaagcagcat atctggtgag ttggccagcg ctaaatgtgc ttgtctatag
    16801 tgccaacgtt gaacaggccg tcgactctgt gagatatgat cttattatgc cctccaaata
    16861 ggctataaaa tagaagtact cttatattga cataatttat tcgagatata ccacaaataa
    16921 tgataattgc ggctaagaag gtattcgggc caatcttaca tgctccagct gggcctgcgc
    16981 actaaaccac acgaaacctt tcgggaagat attgatttcc aataggcata gagtagaccg
    17041 tgaccgtgta gattgtgttc cttttcttcc ccgctagcct tatctctgtt cttgtctcgc
    17101 aaaccctccg cagagccgcc acactcctcc aagcaaaacc ctccaggaag aaataacccg
    17161 gcaagaaaat tgccggatga atctgccggg cgaaattcat cataggttta cttatatgta
    17221 cattgcgcag gtcagctttg cagacctcga cattaccaaa cacaacttac caatctcaac
    17281 gatgtcttct tcagattccc cgaactatgg cgatgccacg atgcccattg ccatcgttgg
    17341 catggcagcc cggttctctg gtgaagcaac taacccatcc aagttatggg atatgatggt
    17401 acagggtcga actgggcatt ccgcagttcc agagaatcgt ttcgacgcgg aggcgtggca
    17461 tcatcccagc cacgaacgaa gagggactgt aggtttatga attcaaaatt ggcaaaaaaa
    17521 atggattgat gcaacgtgct aatgatgcca tatggctaga tccaaccacg aagtggcttc
    17581 ttccttcgtg aggaccctgc cgtttttgac gcaccatttt tctcgatgac ggcgaaggaa
    17641 gctgcaggaa tggacccaat gcagagaaaa cttttagaaa tttcttacga ggcttttgaa
    17701 aatggtaggc tgtccgataa gaaatatccg taaaaacaga aatgctgaac tcaaccaaca
    17761 gctggcatcc cgattaccaa gttgcctggt acggcgaccg gcgtctacag tggtgttatg
    17821 acgaacgact atgagttgat gactgccggt gatccaatgc agttgccaca gaatgcagca
    17881 tcgggaacaa gccgtgctat gcttgccaat cggatttcct ggttctatga tcttcggggt
    17941 cccagcttcg cgctcgatac ggcttgctcg tccagtttat atgcgctaca cctggcttgt
    18001 cagtcactgc aagcaggaga gactgaccag gtacgcatac tcactcgcta ggaaggaaga
    18061 ccagcgttga cagtgattac aggcgctcgt aacaggagtc aatcttatcc tagcgccaaa
    18121 ttttatctcc cagctttctt cgatgcacat gctgagccca gacgggaaga gccattcttt
    18181 cgactctcgt gccaatggct acgccagagg cgaggccctt gctgcagtcg tggtcaaacc
    18241 actctatcaa gcactcgctg acggtgacac tatccgagca gttattcgag gaagtggtgc
    18301 aaatcaagac ggtaagaccg ttggaatcac aattccaaac ccgcaggcgc aagcagaact
    18361 tatccgcaaa acatacgcta cagctgggct gggtctcgaa cagacagggt atttcgaggc
    18421 acacggcaca ggaacccctg taggtgatcc aatcgagctg agcgctattg ggacaagttt
    18481 cggcgagcat cgcagccaga actgtccgct ttttgtggga agcgtgaaga cgaatgttgg
    18541 ccatacggag ggggctgccg gtctggcagg cgttgtgaag acagtgctag ctctggaggc
    18601 gggtattatt cctccactgg ctgactttca ggagctgaat gaaaagcttc gacttgagga
    18661 gtggaagttg gctctcccgc tcaaagcaac tccttggccg atgccgggtc ttcgccgggc
    18721 aagtgtcaac tcgttcggtt ttggaggtgc caatgctcat gttatccttg atgatgccta
    18781 tcattacctg aaatcccacg ggctgagcgc aaaccatcat acaacactgt cggaaagcga
    18841 ggactcatcg gattcaggtc tggaaatgga ctcctcaacc agtgacagtg gggaagggca
    18901 gtcgagcaag ttgttacttt tctcagcgta tgatggcgct ggtattaaaa ggacagaagc
    18961 ctcgtggaac agccaccttg ccgatatcct cgcagacagc aaaaccgtgg acgagaccat
    19021 ggggatgaat gacctcgcat acaccctttc tgaccgccgc acgaccttcg acttccggag
    19081 ctttgctgtg gcatcgagcg tacaagatct gaaagctaag cttgagaacg acggccttcc
    19141 gcgactgaac agggcctctc gtcgctccaa ccctgtgttt gtgttcacgg gccagggagc
    19201 ccaatggccc gcgatggggc gagaactgct gtctaaccct atctttcgcg ccagcatcga
    19261 gcgtagcaaa gccgttctcg aacttgaagg ctgcgagtgg gatgtggtgc aagttttgtc
    19321 agatccgcag gaccagcgca tccatatccc agccttttcc caaccagtct gcacaatctt
    19381 acaggtcgct cttgttgatc ttctgcagtc atggggcatt caacctgcag caacggttgg
    19441 tcattccagt ggagaggttg cggcggctta tgcagcgaaa atgatatccc aggacgaggc
    19501 tgtacgaatt ggatactggc gaggcttcta cagtgagcag gtgaaggctc gactagaaaa
    19561 tatacgaggt tccatgatgg ccgtcggtct atcagaatct caggccactt cgtacctaaa
    19621 ccgggtacca gaaggcagtg tagtcgttgc ctgtatcaac agcccgtcca gtgtcacttt
    19681 atctggcgaa gatcattcga tcaagactct cgaagcaatc ctgcaggcag acggccactt
    19741 tgcgcgtaag cttcgtgtgg aggttgccta ccattctcct cacatgaaga ccgttgcaga
    19801 tgagttcctg aacgctgttg gcataatcac tccacagcct tctgaaatcc cgatgttcag
    19861 ttcggttacg gaaacccggg ttgaggaccc agcgactctc gttgcttcat actggatgca
    19921 gaacctgata tccccagttc gtttctctgg tgcactagca accctactaa atgacacccc
    19981 cagtgtaaag gcaaatactc gccgtcgacg cactgctggt attgtctgga gtgctctgat
    20041 cgaggttgga ccccatgagg cactgaaagg gccatgccgt cagatcatgt cgggcctaaa
    20101 caccaaatta gcagaccaga ttccttatat gtctgtcctt agccgcggta agagtgcagt
    20161 ggagacatca ctgacagcag ctggcctcct ttgggcgtcg ggacatccga tcaatatacg
    20221 tgaggtaaac cagtatcggg atactggtga gagggtgatc actgacctgc caccgtaccc
    20281 ctggaaccat gaaaagggct tttggcatga acctgcggcc tctatatccg cacgattgag
    20341 aaaagaacca cgcaacgatc tcctgggtgt gccagtggcg cagcaaaacc ctttcgagcg
    20401 gtgctggcaa aactatctct ccgtctcaga atgtccttgg cagaaagatc acgtcattac
    20461 tggcactgta ctgtatccgg gagctggaca tctgattatg gcctttgaag ctgccatccg
    20521 gctggctgct gacaatagac cgctgaaggg agtctcgttc tctgatgtcc actttgacaa
    20581 ggggcttgtc atcccgtcgg acgaccatgg cgtcgagaca cgactctgca cacggcctca
    20641 tgagagcctg ttagactggt accactacac tttatactcc atcaacgcca ctggagactg
    20701 gacaaaacac tcttggggct cgttcagcct ccactacgag gatgctgtca gcgtgcagca
    20761 agcgaaacgc agcaaaggcg aatacgacga tatcaacact cgtgcatgtc ggaagctgga
    20821 tgttgagtcg ttctacgagc agctcctgtc aatcggcaca gaatatgggc cgacattccg
    20881 caacttagta catgctgctg cggctcctgg ttaccacagc ggcgtgggta ccatcacaat
    20941 accagacact aaatcagtca tgcctcacga gtttgaatat cctcacttga tccatcccgc
    21001 cacgctggat gccatctttc acttgatatt cgtggccatg ggcgagggca acgcgctctc
    21061 cgagtctgcc atcccaacac gggtagaccg catttacatt tccacggatc tgcctcgagg
    21121 tgtcggagcc aagtatacag gttacggtcg cgcggagcct gtctccagcc gcgatacctt
    21181 ggggactatc gtcgtctcgg atgaaaattg gtcagcagga cccaagatca ttgttgaagg
    21241 gatgactgtc acggaagtct ctgctggtgc ttctacctca ttcaactcct tgcttatacc
    21301 ggggggccaa ggtcgcattg ccacgcttga atggaaggag gatgtggact cacttgtcgg
    21361 gccgacggct gagtcgtggc tggcccagaa agggccaagt attgggggcc aggccagcga
    21421 tgtgactgaa gcggtgcagc gcctcgacgc ttggctggaa ctttcctgtt tcaagagcac
    21481 agaccttggc acccttgtta tatgtccctc gaaattgaaa ggcagttttg aactcgtcaa
    21541 gaaatatggc tctaagcatg gagaaaggta tcggttcggc cggaccacga tcatcgaatt
    21601 ttccgagaat gatatttcag cagcagagag tgctttcgca ccgcacggaa ttgaatcttc
    21661 atatgctgct atcgatcttt cagccactcc tgagcatgct atggaacaat tggggatgtt
    21721 cgatttgatc atcgctgagg agaatgttat tgtccaattt cccgatgtca caaagatact
    21781 gcatcgggaa ggcagagtcg ctattattag gagtcatgct ttacccgatg agcgccactt
    21841 cgcagcaaca aagggcttac tgaaggaaat ctcatttgag tctcaggacg gctctatcct
    21901 acaaattgct ggtttgggat tggaaatgga tccagccatt cgcagccttg atgacgttgt
    21961 actgttacaa catgtagatg cttccccagc tgccaaaaac tttgaaaaaa ggcttacggc
    22021 ccagctaacc agtctcggtg cgcatgtacg gagcaatacc atagcaaacg cgagcagcct
    22081 ttcaggaaac atcgtgatct ctttgctaga gattgattgt caatttgtca tatcatggac
    22141 atcggaagaa ttcgaacaat tccgccagct gaccaacgcg agatacgtcc tatggattac
    22201 gcgcgggggc ttgctcgacg cagaccgggc atcgcttgat tatgcgccgt ccaccggcct
    22261 tctgcgtact gtccgcgttg aaaagcccca aattcgactg cctcacttgg atctctcccc
    22321 tagcctggac ttgaactcgg atcgcgcggt tgaaattgtg atatctgcat tccactccag
    22381 catcaagccc tctgtaaagg aaaagaatct cgaaatggaa tatgcagagt ccaacgggct
    22441 attatacatc ccaagagctc gagggcatgc ggccttagac cacgagcttg cccttcgggg
    22501 tgagaaagtg tccagcatcc cggggccact gtctgcgcct ggaatagcac gacgacttga
    22561 gacttccctg gctggaagcc catctcaggc tcgctgggtt cctgacgaga cagtcggaga
    22621 taagctggca gattttgatg ttgaaatcca ggtctctcac gtgggcttgg agcacagtaa
    22681 ggtcgaaaat tatctaaatg gaaaacagct ttcgctagca cctggcctcg ggcgcgtggc
    22741 agttgggacc ctgaccaggg ctggtgcaaa agtttcacga ttcattcctg gtgaccaagt
    22801 gtttgctttg cacgccgcac ctttccatac acacctgcgc gtcaccgaag acgctgtcca
    22861 cgcagtcccg gacatcctgt ctccagctca ggctgcacat cttccgctag ctgcggctcg
    22921 agcctggcac tcgcttatcg atgttgcagc gttccgcgct ggtcaatctg tctttgttaa
    22981 tggtgcaagc gatactgtcg ggcgactaac tgttgagctg gcgcggcttc tgaaggggga
    23041 tgtttttgcc tctgttagct ctgatgacga aaagcacact ctgacgaaaa cctacaacat
    23101 accagaagat catattttca gcctttcaca ccgaactgac tgggcatcag acctcaaagc
    23161 cgcgatggga caggggcagc tagatattgt gatcaacaac gcaacgccaa gcccagcaat
    23221 tcgcagcctt ttccaatcaa ttgcaccaaa aggacgattc gtagacctta cccagcgtct
    23281 cgatccgtcg ttgctcgacc caaggatgtt ccagcggaac gttactttgt ccttggtgga
    23341 ttgggagtct ttgaccaacc cgcagctggg cgccctgatg gttagatcac tagatttgct
    23401 acgagcaggg gccttaaccc cgatcaagga agaatatatc ttttcggtat ctgacctgcc
    23461 agaagcatta ttgtccgtcg gccaacagca acatgagcga gtcgcagcac cggtggtggt
    23521 ggagttctcc gcagatgcca cagttccttt acttccatct cttcccgcac cacttcacct
    23581 taaacccgat gcgacctata ttctcgctgg ggggctgggt gctcttgggc ttaccattgc
    23641 agagaatatg tgtagccacg gtgccggcca cttggtgttc ctcagccgct ccggggcatc
    23701 gagccaaaga cagcaagagg cgcttgagag cttccgtgct cgcggatgca aggtcgacgt
    23761 ggtgaagtgt gacgtgacgg accaagaaca ggtgcaagct ctggctaccc agattcggga
    23821 gcaatcgtgg aatgttcgcg gcatcatcca actggcaatg gttctccggg tatgtaattg
    23881 gacttcattc accgtgaccg gctaacccac tgaccttatt gcttgcagga ctcgatcttc
    23941 gaaaatatga ccttcgataa gtgggaaaca gctgtcaacc ctaagatcaa aggaacgtgg
    24001 aacctgcacg ccgagcttcc caaggatgtt gatttcttca tcattctctc ttcgctctct
    24061 ggcatcattg gaaatactgc ccaagctaac tactgcgccg gtaatacata tgaggacgct
    24121 cttgcccatt ataggcgtaa gcagggcctc gccgcgacga ccctcaacgt cggcctggtc
    24181 acggacgcaa gccacttcaa cgagaattcc acaatcgaag actatctgcg taaatatagt
    24241 cactggatag ccgcccaggt caccgacagc gagctgcagc acaccatcac tgccgtgatg
    24301 cggaggacag tcggcgacaa gaatgagccc gtacccgacc agctcctggt cggtctctca
    24361 gataacgtcc ggcgtgacgg aaacagtctg aatttgtggc cacaggaccg caaattcgac
    24421 cacaggatca gtctagaaga tgggctcggt gtggttgaga aggatacgaa tcaacagaaa
    24481 ttaaaggcat ccacgacagt cgctcaggcg cacgaggtcg ttgagacagc attacgcttg
    24541 aatgttgccg cggctatgac tgcctccccg gatgatattg acattgagaa accgctctat
    24601 gcctttggca gtatgtattc atctctctct atccttccgt ctcatctcat cacagctcca
    24661 ttcgcttcct gcccagttac taacatgtag acagttgact cgcttaaagg gattgaagtc
    24721 cgtaattgga tttttagcga gctgcaggcc gatgtatccg tgtttgaggt tcttagtccg
    24781 atgaccctaa gccgcctggc tctcaagatt gtttcgaaga gcacgctcgt gggcgcggag
    24841 cttgctgcag aagctgcggc ggacagtgtg gcgtaagatt ttggctatac cacatggcat
    24901 gatatactac cagatgccag gtataggatc tgcttactag ttggggcctt taggtcgtct
    24961 gtttgtcacc ttcacattat aactctaaac tcggcatata gaatttccga tttccagata
    25021 gaatatacaa gactattgac atcacctcct ataggacgaa atcaaggttg ccaaatgttt
    25081 ttagcatcat tagccatagc ccaaacagtc gtttagaagc agataggaac tcgacgaaag
    25141 catgaaatac ctgaaagtag aatgactggc gac
//
