LOCUS       BGC0002185             28322 bp    DNA     linear   PLN 14-APR-2020
DEFINITION  Penicillium sp. sh18 DNA, gregatin A biosynthetic gene cluster,
            complete sequence.
ACCESSION   BGC0002185
VERSION     BGC0002185
KEYWORDS    .
SOURCE      Penicillium sp
  ORGANISM  Penicillium sp.
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Penicillium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 07:32:21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 28322
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..28322
                     /country="China"
                     /db_xref="taxon:5081"
                     /mol_type="genomic DNA"
                     /organism="Penicillium sp."
                     /strain="sh18"
     subregion       1..28322
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Polyketide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..28322
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             complement(101..1645)
                     /codon_start=1
                     /product="putative glucan synthesis regulatory protein"
                     /protein_id="BCA42567.1"
                     /transl_table=1
                     /translation="MTSYDRHASHDSPYRTGRHVPLSQSRHQPLTSIATSAIESRPDLS
                     SPYHDEPTKGLASAQATEWNGSPTEVGSPNRPYSPGMRSLASQKPGSNEQADGPAEIQM
                     QSFHDGAPPPPPVAHSWRKIERWLEHNYEELLDNLGEGCTQNDINELEHELDCTLPLEL
                     RESLMIHDGQERPGLPTGVLFSSMLLDCEEIVQERRNWKTVNEEFLSHNAPISAPISSS
                     AASSSSAAAQQQSNPGAWRNELLERQDSQPPGAVQKAYAHPGWIPVARDWGGNHIAIDL
                     APGPAGKWGQVIIFGRDYDCKYVIARSWAAFLAIFAEDLCSGKTFINEETNEMKLREFK
                     SQNVEPPYLEILRWRTDQKYGRRAPRRRGPNGVGVNANGKSSSRDSPYGSPTRAEERGR
                     SPHRFSKGSTQSPKTTFGVSSPLARVTEEISSPVATAGPTISEDSREHSKEAEQTEDLM
                     EVATPQISNKENEGFPEKTSETKLPESEKSEKSDGTAEPSSAIDSEVLGEMKNVAI"
     gene            complement(4300..11958)
                     /gene="grgA"
     CDS             complement(join(4300..10715,10778..10915,10973..11153,
                     11216..11692,11749..11958))
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (17-446). E-value:
                     4.7e-174. Score: 571.1. Matches aSDomain:
                     nrpspksdomains_grgA_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (558-878). E-value: 1.6e-93.
                     Score: 305.1. Matches aSDomain:
                     nrpspksdomains_grgA_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (955-1138). E-value: 8.1e-25.
                     Score: 79.9. Matches aSDomain:
                     nrpspksdomains_grgA_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1392-1597). E-value: 5.9e-73.
                     Score: 237.2. Matches aSDomain: nrpspksdomains_grgA_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2106-2279). E-value: 1.6e-51.
                     Score: 166.6. Matches aSDomain:
                     nrpspksdomains_grgA_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2383-2451). E-value: 6e-10.
                     Score: 31.2. Matches aSDomain:
                     nrpspksdomains_grgA_PKS_PP.1"
                     /codon_start=1
                     /gene="grgA"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 220.2; E-value:
                     8.2e-67)"
                     /gene_kind="biosynthetic"
                     /product="polyketide synthase GrgA"
                     /protein_id="BCA42568.1"
                     /sec_met_domain="PKS_AT (E-value: 2.7e-94, bitscore: 305.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.1e-178, bitscore:
                     583.5, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.9e-45, bitscore:
                     144.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MGSIETEGNPPYFAREPIAIVGSSCRFPGGATSPSKLWELLEKPR
                     DVLQEIPATRFNTKAFHHPDSQHHGSTNVKHAYLLDEDPRAFDRDFFSINPKEAEAMDP
                     QQRLLLETVYEGIESTGHSMQQLRGSTTAVFVGCMSFDYHLTAIRGIDSLPQYHGTGTA
                     ASILANRVSYFYDWKGPSVTIDTACSSSLVALHQAVSALRNGEAEMAVAAGSNLIIGPE
                     PFVSESKLNMLSPNGRSFMWDAAADGYTRGEGFAAVFLKTLSQAIADGDHIECIIRETG
                     VNSDGKTPGITMPSSESQARLIRDTYARCGLNPARESDRPQYFEAHGTGTQAGDPIEAR
                     AIQSVFFPNEREGQLIVGSIKTVIGHTEGTAGIAGVLKASLAVQHGQIPANLHFKDLNP
                     KIRPYYTNLRIPTETTPWPAVSKGYPRRVSVNSFGFGGTNAHAIIESWDGAGSLTNGYA
                     LNGNTLKPLGAGPFVLSANSGAALAANAGALADYLRAHPDADLRRLAYTLFRRTDFPFR
                     AAFSATSVEQLAEKLEAGKDSLKSSSRTATIPEVLPPRILGIFTGQGAQWATMGKELYG
                     ASSVFRSAIDQMQRALNSLPIEDRPDWSLVDQLDAPAVDSRVGEAIVSQPLCTALQVAL
                     VDVLRAAGVELSAVVGHSSGEIGAAYAAGYLDATDAIRVAYYRGFHSHLAQGPGGKRGK
                     MMAVGMSLNQATTFCSEFGGTLTVAASNSQTSCTLAGDAEAIEDAHARLQEKGTFARVL
                     QVDTAYHSHHMKPCAIPYLESMKQCGVTVQKGGKQCRWYSSVWGSDGRSRSFNQADGLL
                     LEGQYWVDNMTQPVLFSQALARALNEDQYFDLALEVGPHPALKGPSAETIKMLTGLSLP
                     YSGVLKRGQNAVTSFSDALGLLWTSFPSSRPLITFDGVRRAFPSREPLKLAVLKGLPAY
                     SWDHPGLIWKESRTSRIFRTQSQPRHELLGHSVTHGERDKREVHWKQLLRLNELPWLAG
                     HRIQGEVLFPASGYLSMAYEAATRLVDDRQPLRLVELHDIDIVRAMRLEQDSSGLEVVF
                     TVRVTAQSDDCITAEVACYSGAVDSVQPLDAPQTGLTAHFTGGVRLWLGEPSTDTLPSR
                     KTPLLPMEALDMEQLYSNLAKEGFNYADLFQAKSMHRRLNRAVVTVSSPSEPSSMRECV
                     HPAPVDTAFQGLLAGFSFPGDGRLGTIYLPTRVECVRVNMMPSESHATVLTADATVTST
                     GKTTLTGDVDLFDAANARTQVQIRGIHLSAVGQRRDPWLYAGTTWARDVSYGIEPSIKT
                     KLSEADWVLYEQLSRTAYFYLRQLRKKILPQELMLMGKYRKHMMTWVLEHLLPRIEAGE
                     HPEIRAEWKDDTLEMVQQWRASQPSDNNDMNILHAMGKNLVGIVRGTTPPLRVLTQDGM
                     LDRLYVEGLGARDGNHDLAGFVKQLAHQYPRMRIAEVGAGTGGTTRAVLDALGNQYASY
                     TYTDISTGFFENARTLFGQHSSKLSFKTLNIENDPVDQGFPEGTFDMVISSNCLHATRS
                     LGETLRHCRQLLQPGGRLVLLEITRDFLPTQLVMSTLPGWFLGIEDGRVWAPTVSLERW
                     DELLKANGFSGVEISSTPSFCSVIVAQAVDETVQLLREPLAVAPTALPPLGDILIVGGG
                     VTSELASQIQKPLQAAAPSNTVTVLPGLEGIEVPKGAAVLCLSDLDSPVFRDMNSKRFR
                     GLQNVMESAEVVLWVTSGAKSGNDPDANITLGLSSTLRAERMDLRLQFLDVDEPSSVDP
                     SMLASMLLRLAFLDPSKNDELLWVQEPELALKEGALYVPRVVSLDTLNRRSAARHRQVT
                     QLTSVGSEDVAVVVDERQGAFELQTIPFGGATKDEICLQVLASSIRTITCDEYGPVYVC
                     IGRDLVSGDTALALSAVNSSVVKVSEDHILYRWQDDKTTAEYTAHLHLFLVRALAEHLL
                     GSLKGPTWIHGAPHGLREVIDVVAREQSVAVFQTTSDMAMTSDVNFIHPYANKEDLQDF
                     RPKGLQSFINLARQEHRALSAFIHASLPASAIVNKDVASLTASLILPELRILAKQNIHD
                     GLQVPTESVEIVAIDKVSTVTSKELGPAVLIDWSTADTINALVRPLEHRGLFAPDKTYL
                     LCGMTGDLGISVCLWMVENGARNVVLTSRNPNISPSVLNYLSHKGATVRPMAVDITNMD
                     SLRSAYNDIKSSMPPVGGVMNAAMVLRDRLFHHLPWEDFAAVLGPKMVGSKNLDELFGN
                     EQLDFFVCFSSTTSIVGSIGQSAYAAANHYMASLVQQRLQRGLAGSVIHIAILTGFGYI
                     FRRDSEHAETIYKAILPRFDRQSETDLHEMLAEAIVCGRPGSAQPAELITGIRSVFQGE
                     WRDDPRLSCYIGQQQLQDDSSGEQAAGSVSVKDQLASAEDPAECLVILESCFALSLGNL
                     LEIDPEQLDHNMPVANLGIDSLVAIRIREWFLREMGVDMPVLKIMSDTYSMSRMCDDAL
                     VEWRRLNKS"
     misc_feature    4300..27024
                     /note="gregatin A biosynthetic gene cluster"
     aSDomain        complement(4369..4572)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_grgA_PKS_PP.1"
                     /evalue="6.00E-10"
                     /label="grgA_PKS_PP.1"
                     /locus_tag="grgA"
                     /protein_end="2451"
                     /protein_start="2383"
                     /score="31.2"
                     /tool="antismash"
                     /translation="AEDPAECLVILESCFALSLGNLLEIDPEQLDHNMPVANLGIDSLV
                     AIRIREWFLREMGVDMPVLKIMS"
     aSModule        4369..11907
                     /complete
                     /domains="nrpspksdomains_grgA_PKS_KS.1"
                     /domains="nrpspksdomains_grgA_PKS_AT.1"
                     /domains="nrpspksdomains_grgA_PKS_DH.1"
                     /domains="nrpspksdomains_grgA_cMT.1"
                     /domains="nrpspksdomains_grgA_PKS_KR.1"
                     /domains="nrpspksdomains_grgA_PKS_PP.1"
                     /iterative
                     /locus_tags="grgA"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(4885..5403)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_grgA_PKS_KR.1"
                     /evalue="1.60E-51"
                     /label="grgA_PKS_KR.1"
                     /locus_tag="grgA"
                     /protein_end="2279"
                     /protein_start="2106"
                     /score="166.6"
                     /tool="antismash"
                     /translation="KTYLLCGMTGDLGISVCLWMVENGARNVVLTSRNPNISPSVLNYL
                     SHKGATVRPMAVDITNMDSLRSAYNDIKSSMPPVGGVMNAAMVLRDRLFHHLPWEDFAA
                     VLGPKMVGSKNLDELFGNEQLDFFVCFSSTTSIVGSIGQSAYAAANHYMASLVQQRLQR
                     GLAGSVIHIA"
     CDS_motif       complement(4924..5031)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_grgA_0010"
                     /evalue="1.60E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="grgA"
                     /protein_end="2266"
                     /protein_start="2230"
                     /score="56.0"
                     /tool="antismash"
                     /translation="LDFFVCFSSTTSIVGSIGQSAYAAANHYMASLVQQR"
     CDS_motif       complement(5302..5400)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_grgA_0009"
                     /evalue="1.00E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="grgA"
                     /protein_end="2140"
                     /protein_start="2107"
                     /score="47.0"
                     /tool="antismash"
                     /translation="TYLLCGMTGDLGISVCLWMVENGARNVVLTSRN"
     aSDomain        complement(6931..7545)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_grgA_cMT.1"
                     /domain_subtype="cMT"
                     /evalue="5.90E-73"
                     /label="grgA_cMT.1"
                     /locus_tag="grgA"
                     /protein_end="1597"
                     /protein_start="1392"
                     /score="237.2"
                     /tool="antismash"
                     /translation="PLRVLTQDGMLDRLYVEGLGARDGNHDLAGFVKQLAHQYPRMRIA
                     EVGAGTGGTTRAVLDALGNQYASYTYTDISTGFFENARTLFGQHSSKLSFKTLNIENDP
                     VDQGFPEGTFDMVISSNCLHATRSLGETLRHCRQLLQPGGRLVLLEITRDFLPTQLVMS
                     TLPGWFLGIEDGRVWAPTVSLERWDELLKANGFSGVEISSTP"
     aSDomain        complement(8308..8856)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_grgA_PKS_DH.1"
                     /evalue="8.10E-25"
                     /label="grgA_PKS_DH.1"
                     /locus_tag="grgA"
                     /protein_end="1138"
                     /protein_start="955"
                     /score="79.9"
                     /tool="antismash"
                     /translation="HELLGHSVTHGERDKREVHWKQLLRLNELPWLAGHRIQGEVLFPA
                     SGYLSMAYEAATRLVDDRQPLRLVELHDIDIVRAMRLEQDSSGLEVVFTVRVTAQSDDC
                     ITAEVACYSGAVDSVQPLDAPQTGLTAHFTGGVRLWLGEPSTDTLPSRKTPLLPMEALD
                     MEQLYSNLAKEGFNYADLFQ"
     CDS_motif       complement(8689..8766)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_grgA_0008"
                     /evalue="1.10E-12"
                     /label="PKSI-DH_m2"
                     /locus_tag="grgA"
                     /protein_end="1011"
                     /protein_start="985"
                     /score="40.2"
                     /tool="antismash"
                     /translation="WLAGHRIQGEVLFPASGYLSMAYEAA"
     aSDomain        complement(9088..10047)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_grgA_PKS_AT.1"
                     /evalue="1.60E-93"
                     /label="grgA_PKS_AT.1"
                     /locus_tag="grgA"
                     /protein_end="878"
                     /protein_start="558"
                     /score="305.1"
                     /tool="antismash"
                     /translation="IFTGQGAQWATMGKELYGASSVFRSAIDQMQRALNSLPIEDRPDW
                     SLVDQLDAPAVDSRVGEAIVSQPLCTALQVALVDVLRAAGVELSAVVGHSSGEIGAAYA
                     AGYLDATDAIRVAYYRGFHSHLAQGPGGKRGKMMAVGMSLNQATTFCSEFGGTLTVAAS
                     NSQTSCTLAGDAEAIEDAHARLQEKGTFARVLQVDTAYHSHHMKPCAIPYLESMKQCGV
                     TVQKGGKQCRWYSSVWGSDGRSRSFNQADGLLLEGQYWVDNMTQPVLFSQALARALNED
                     QYFDLALEVGPHPALKGPSAETIKMLTGLSLPYSGVLKR"
     CDS_motif       complement(9238..9285)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_grgA_0007"
                     /evalue="2.90E-03"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="grgA"
                     /protein_end="828"
                     /protein_start="812"
                     /score="10.4"
                     /tool="antismash"
                     /translation="LEGQYWVDNMTQPVLF"
     CDS_motif       complement(9688..9795)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_grgA_0006"
                     /evalue="1.50E-10"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="grgA"
                     /protein_end="678"
                     /protein_start="642"
                     /score="33.4"
                     /tool="antismash"
                     /translation="GVELSAVVGHSSGEIGAAYAAGYLDATDAIRVAYYR"
     CDS_motif       complement(9997..10044)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_grgA_0005"
                     /evalue="1.20E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="grgA"
                     /protein_end="575"
                     /protein_start="559"
                     /score="17.8"
                     /tool="antismash"
                     /translation="FTGQGAQWATMGKELY"
     aSDomain        complement(join(10384..10715,10778..10915,10973..11153,
                     11216..11692,11749..11907))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_grgA_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="4.70E-174"
                     /label="grgA_PKS_KS.1"
                     /locus_tag="grgA"
                     /protein_end="446"
                     /protein_start="17"
                     /score="571.1"
                     /tool="antismash"
                     /translation="IAIVGSSCRFPGGATSPSKLWELLEKPRDVLQEIPATRFNTKAFH
                     HPDSQHHGSTNVKHAYLLDEDPRAFDRDFFSINPKEAEAMDPQQRLLLETVYEGIESTG
                     HSMQQLRGSTTAVFVGCMSFDYHLTAIRGIDSLPQYHGTGTAASILANRVSYFYDWKGP
                     SVTIDTACSSSLVALHQAVSALRNGEAEMAVAAGSNLIIGPEPFVSESKLNMLSPNGRS
                     FMWDAAADGYTRGEGFAAVFLKTLSQAIADGDHIECIIRETGVNSDGKTPGITMPSSES
                     QARLIRDTYARCGLNPARESDRPQYFEAHGTGTQAGDPIEARAIQSVFFPNEREGQLIV
                     GSIKTVIGHTEGTAGIAGVLKASLAVQHGQIPANLHFKDLNPKIRPYYTNLRIPTETTP
                     WPAVSKGYPRRVSVNSFGFGGTNAHAIIES"
     CDS_motif       complement(10582..10638)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_grgA_0004"
                     /evalue="1.30E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="grgA"
                     /protein_end="380"
                     /protein_start="361"
                     /score="2.3"
                     /tool="antismash"
                     /translation="TVIGHTEGTAGIAGVLKAS"
     CDS_motif       complement(join(10708..10715,10778..10817))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_grgA_0003"
                     /evalue="2.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="grgA"
                     /protein_end="338"
                     /protein_start="322"
                     /score="13.0"
                     /tool="antismash"
                     /translation="YFEAHGTGTQAGDPIE"
     CDS_motif       complement(11079..11117)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_grgA_0002"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="grgA"
                     /protein_end="254"
                     /protein_start="241"
                     /score="12.0"
                     /tool="antismash"
                     /translation="WDAAADGYTRGEG"
     CDS_motif       complement(11321..11368)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_grgA_0001"
                     /evalue="6.50E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="grgA"
                     /protein_end="194"
                     /protein_start="178"
                     /score="21.2"
                     /tool="antismash"
                     /translation="GPSVTIDTACSSSLVA"
     gene            order(12498..13018,13077..13611)
                     /gene="grgB"
     CDS             join(12498..13018,13077..13611)
                     /NRPS_PKS="Domain: PKS_ER (25-227). E-value: 6.4e-28.
                     Score: 89.6. Matches aSDomain:
                     nrpspksdomains_grgB_PKS_ER.1"
                     /codon_start=1
                     /gene="grgB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 189.5; E-value: 1.4e-57)"
                     /gene_kind="biosynthetic-additional"
                     /product="trans-acting enoylreductase GrgB"
                     /protein_id="BCA42569.1"
                     /sec_met_domain="ADH_N (E-value: 2.4e-10, bitscore: 29.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.7e-12, bitscore:
                     36.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MPTTMQALVGAESGGYRLAENVDIPVPQRGSILVQVHAVALNPRD
                     AKIVDFSNAPGSLGGCDFAGTVKKVGEGVTRFKEGDRVLAVTFGSNALDKTKGAFAEFA
                     LAEEDISCRIPEDFSFTQACSIGLSMATAGLAIFQAPGLELSLHGGKGEAVLVSGGATA
                     TGTMATQLLRMAGYTPIVTCSPANNALCQSYGAAACFDYHSPACGADIRVQTNDSLRYV
                     LDCVTDTTTMKMCYEAIGSSGGSYIALETIATTVKYTRRDVRADWFLADAIMGNGVQMA
                     GTYGRAPSPELRRFGKQLFALAENWLHDGSIRHHPLEIQDGGLANMPQALNDMKLGKVH
                     AKKLVVPILGH"
     aSDomain        join(12573..13018,13077..13236)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_grgB_PKS_ER.1"
                     /evalue="6.40E-28"
                     /label="grgB_PKS_ER.1"
                     /locus_tag="grgB"
                     /protein_end="227"
                     /protein_start="25"
                     /score="89.6"
                     /tool="antismash"
                     /translation="VPQRGSILVQVHAVALNPRDAKIVDFSNAPGSLGGCDFAGTVKKV
                     GEGVTRFKEGDRVLAVTFGSNALDKTKGAFAEFALAEEDISCRIPEDFSFTQACSIGLS
                     MATAGLAIFQAPGLELSLHGGKGEAVLVSGGATATGTMATQLLRMAGYTPIVTCSPANN
                     ALCQSYGAAACFDYHSPACGADIRVQTNDSLRYVLDCVT"
     gene            order(16161..16320,16421..17475)
                     /gene="grgC"
     CDS             join(16161..16320,16421..17475)
                     /codon_start=1
                     /gene="grgC"
                     /product="transcription factor GrgC"
                     /protein_id="BCA42570.1"
                     /transl_table=1
                     /translation="MSHRQSCDRCRQQKVRCLRDEALGGESNPVSPGRSSLSPCERCLK
                     AGVDCVYSLKQRSNRRSVQTSIRRDTDPGSRNGSNASWLEQGLARPMYQGGPFLGADLG
                     DLVGQFSGVGEGGPVASFNGWDANLQPFSPTLFSSLVAPVGTNTGPISTAPSTTDGGHD
                     SEEIDDNRDPTDALSSQLTSLGQRARRAMRRLVLPDRTPLTVSSPEVNEALEDTNTLIR
                     IMNKITAPDRDDITIFPTTTNYSLAFSALACHQHLVALFRAICDAIHRCLQSQKEPRQR
                     HNRSGQTSDVGPSSVAQFVMVLQLLMHLINRMDRSLFQSTSSMRHGSRISVSTGSHLAP
                     VTPSTANHVTPDPTRIEAAAGSSVPPGGLLVLVQDIVETIPNEHEKLRQVIQKLQTEME
                     HSELH"
     gene            complement(18307..19382)
                     /gene="grgD"
     CDS             complement(join(18307..18592,18645..18774,18830..19095,
                     19148..19258,19318..19382))
                     /codon_start=1
                     /gene="grgD"
                     /product="O-methyltransferase GrgD"
                     /protein_id="BCA42571.1"
                     /transl_table=1
                     /translation="MASEKPQESVYYLKPGDEERARLNNQHRVLVHIIENELLHAPIDP
                     STIVKIADVGTGTGIWLDALAAHLDPIPTAIGQPRQYDGLDMSPAHFPAFHPENFHYDV
                     YNILQPVPEGLKGKYDLVHVRLLVSALSKGDVNTAVDNLAQLLRPGGWIQWDELDGESW
                     AGRVPSAHVREMNELVRKHMETKGMELDVPAAFVKAAEAHPRLQNVSERIFNTIKSGPE
                     LKDDVNSVYLWSCTTSTKMILQASGTPGAEEEFKRLSEGAKADIERDGIFWDSDEHVLL
                     AQKK"
     gene            order(20510..20755,20811..21954,22016..22320)
                     /gene="grgE"
     CDS             join(20510..20755,20811..21954,22016..22320)
                     /codon_start=1
                     /gene="grgE"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 331.6; E-value:
                     9.5e-101)"
                     /gene_kind="transport"
                     /product="major facilitator superfamily transporter GrgE"
                     /protein_id="BCA42572.1"
                     /transl_table=1
                     /translation="MAENQVDPKRNLPLYGAADESTSATDKEDEVENVRQNGSAPPIEE
                     ARESNEAPAADEYPHGLSLFFIVLAIMLATFIISLDQTIVGTAIPKITDQFHGLDKVSW
                     YGSAYFMTFGGFQTSMGKAYRYFSLKTTFLVSLFIFEIGSLICGVAPNANALIAGRAIA
                     GLGGAGMATGGFTIIAFSSEPKRRPLFTGLVGSAYGLSAVAGPLIGGAFSDKVSWRWCF
                     YINLPVGGLAAVIILIFFHSPSGAKPVKAPLKEKILNMDLVGVSLLMCLIICFILALQY
                     GGQTESWNSSKVIGLLVGFVAILVALIIWEYYLGERAMLVGRLLKKRALWAPSTYMFFF
                     AGSYFILLYYLPTYFQSIDDTSPIGSGVRNLPMVVTFSIAAILAGAFVERTGIATPVML
                     VGAAIATIGTGLIYTWDIGTPAGKWIGYQILAAFGFVIPWLIPMNIAQANADAQDMSTV
                     TAYIFLAQTLGGAFSVSAAQSAFVNTMLTKIKTTAPDVDPMALIATGATQIRATFPNDI
                     HGVLLAYMAGLKATFAISVGMVGFACLMGLFTPWNRLHGSAGGAAFA"
     gene            order(23347..23466,23534..23656,23726..23865,23981..24482)
                     /gene="grgF"
     CDS             join(23347..23466,23534..23656,23726..23865,23981..24482)
                     /codon_start=1
                     /gene="grgF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /product="alpha/beta hydrolase fold protein GrgF"
                     /protein_id="BCA42573.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.8e-12, bitscore:
                     35.9, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3.4e-11, bitscore: 32.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.4e-09, bitscore:
                     26.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTASTLPRSDVEFTTLDGLTLRGWLFPASQRGPALIMSPGFNMPK
                     DAILPDIAKWFQEHGITCLLYDPRGIGASDGEPRNDIDARQQAEHLHDAVTWFKENPLV
                     NEKQIALWGLCFGGNVTLAAAAFDKRVAAAIAVAPLIDSTGNPERRQPILELAMHDRAS
                     RLDGEEPMYLPYVNEDGSIPNGLQLAAEMMPALERLGIPVENRISVQTYYKSLSWNILN
                     VVQYISPTPAMMVTPELDVSCPTEDQLNCFEHMKEPKELDILKGKGHLDWVFGDVESIL
                     NRQLDFLKRHMAF"
     gene            complement(25282..27024)
                     /gene="grgG"
     CDS             complement(join(25282..25830,25897..27024))
                     /codon_start=1
                     /gene="grgG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 194; E-value: 7.7e-59)"
                     /gene_kind="biosynthetic-additional"
                     /product="cytochrome P450 monooxygenase GrgG"
                     /protein_id="BCA42574.1"
                     /sec_met_domain="p450 (E-value: 3.5e-66, bitscore: 213.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTGFAEIIISPASFIYFPLLILVGHALIFILNTLRPKAFPPGPRG
                     LPGLGNLLQVDRIFPFLTYGKWAKDYGSDTPLGVKKGATNVVVLNSSRLVRELFEKRGA
                     VYSDRPWQFMNNTWIFKDDLKAAIFQNSSPWLTSWRRDFNKNFGPAAITRLRPIYEAET
                     ARLLVKLLEAPTASGKDLEAILVCWMMSVPCLGVCGRRPDSMGDHGFEIKQFRHCSDEY
                     ATLVAPNAGDLFPFLRYLPEFFGMAEWKERARAVREAVLNTGTQFLSAAREQRAALDEG
                     KSIAWESVLAKMLREQREKNDDMFTVTDMGNTAFHIVSAATNTSLAVFSIMLLILAKDP
                     QLQQRVRNEVLEVSGGATPTATDLSSLKYTEAFWNEVHRWRPVAPQGVAHAPSQDDIYN
                     GHRIPKGTAIIMNVWNIHHSEEDYDEPEEFIPERFLQHPLGLRSDHTLDAAHLEASASR
                     VTWDFGAGRRICPGMHSAKHSLLLGLAKVLWAFDILPPEGKEIDLSLETGFVQEIALHP
                     KELNVVLKLRDGRTKQDLMDHYSQTYAAEAEVMGWKDGLYQ"
     CDS             join(27542..27560,27652..27880,27935..28033,28162..28222)
                     /codon_start=1
                     /product="putative stress responsive A/B barrel domain
                     protein"
                     /protein_id="BCA42575.1"
                     /transl_table=1
                     /translation="MTLIHIVLFRFKPEVTQEHRDAFLREVKTLKNLPSVKEGRLIVGS
                     PSLTDPIALSKKFEFALVSYHENIAALEEYEASEEHHRVTSTYMFPFDEDLCRFDFEVD
                     PEDEYMCAFGPFALEFGNPGFFGEIWLTNLE"
ORIGIN
        1 aaaagtggta gaggtaggta aagacacggc gagaaaggaa ggagaacagc aatgaaaaaa
       61 acatttccat ccagcgcgag ttcgagttcc aaactcaaaa ctaaatggcc acgttcttca
      121 tctctccaag aacctccgaa tcaatggcac tcgagggttc cgcagtcccg tcactctttt
      181 cgctcttctc actctcaggc agcttcgtct cgctcgtctt ctcagggaat ccctcgttct
      241 ccttgttgga gatctgcggt gtagcaacct ccatcaagtc ttccgtctgc tctgcttcct
      301 tgctgtgctc ccgggaatcc tccgagatcg ttggaccagc tgtggcaacg ggactcgaga
      361 tttcctccgt cacacgagcc agagggctgg acacaccgaa tgtcgtcttg gggctttgcg
      421 tcgagccctt ggagaaccga tgcggcgagc ggccgcgctc ctcggcccga gttgggctac
      481 catatggcga atcccgactg ctggatttgc cgttcgcatt aacacccaca ccattgggac
      541 cacgtcggcg cggcgcccga cgtccgtact tctggtctgt ccgccagcgc aagatctcca
      601 gataaggtgg ctcgacattt tgcgacttga actccctcag cttcatctcg ttggtctcct
      661 cgttgataaa ggtcttgccg ctgcacagat cttccgcgaa gatggccaag aaggccgccc
      721 acgaccgcgc aatgacgtat ttgcagtcgt agtcgcggcc aaagatgatc acctggcccc
      781 atttgcctgc aggtccgggt gccaaatcaa tggcgatgtg gttgccgccc cagtcgcgag
      841 cgactgggat ccagccgggg tgggcatatg ccttttgcac ggcgcccggt ggttgagagt
      901 cctggcgctc gagcagttca ttgcgccacg cccctgggtt gctttgttgc tgggcagcag
      961 cggaggacga gcttgcggca gagctagaaa tcggcgcaga aatgggagca ttgtggctca
     1021 aaaattcctc attgacagtc ttccagttcc tccgctcctg cacaatctcc tcgcaatcca
     1081 gcagcatgga gctaaaaaga acacccgtgg gcagaccggg ccgctcctgg ccatcgtgaa
     1141 tcatcaacga ctcgcgcaac tccaagggca gagtgcaatc caactcgtgt tccaattcat
     1201 taatgtcgtt ttgcgtgcac ccttcgccga gattatctaa cagttcctca tagttgtgct
     1261 ccaaccaccg ctcaatcttg cgccaggagt gagcgaccgg gggcggaggg ggcgcgccat
     1321 catggaagct ctgcatctgg atctccgccg gtccatcggc ctgctcgttg gaaccgggtt
     1381 tttgagaggc aagcgatcgc atacccgggg aataggggcg gttgggcgag cccacttcgg
     1441 ttggagagcc gttccattcc gtggcttgtg cagatgccaa gcccttggtt ggctcgtcgt
     1501 ggtaggggct ggagagatcg gggcgggact cgatcgcgct ggtagcaatg gaggtgagag
     1561 gttgatggcg actttggctc agggggacgt gtcgaccagt gcgatagggg gaatcgtgag
     1621 aggcatgacg gtcataggag gtcatggtat gccagaagga gcgccatgcc gaaccaaaac
     1681 tagagagcca gggggagtca gcagagaaac gggagatatg agaagagcag cagtaggacg
     1741 atgagcggaa agagagagtg tgtgagaata aaagacgagg agaggagaga agagggggac
     1801 ctacgcgttc gccatgttgt taagatgggg aggggaggct attgtcagaa aggacacagg
     1861 aggacggtca ttggcgaccg agtctccgat cggatcagcg agagtgaggt gtgtgggttg
     1921 gtcaaaaaga agatgagtgt gggatcaagg agaggtccaa agtccaggaa ggcaagcagg
     1981 gaaaaggaag tagtggaaca gccaaagagg agaatgagag ggagagaagt tgtcgagagg
     2041 gtgttggaaa gagggttagg taaggatggg caggcacgaa aaatatgacg gagatggtcc
     2101 tttccccgtg atttgaggat ccaacttttg gagggaccag cttttttttt cttttttgga
     2161 ccgaccactc tcctgacgtt tctcaggtac ctgaaccaaa ccacctggaa gttcgaaccc
     2221 agttagtacc tttcgcttcg atgttgatgc ggtggttggc ctctcctcca gtcagcgtcc
     2281 ccccctggcc gcatccaggt ccttgaccct caggcatgca gatcatgatg tcgtcgctcg
     2341 actcgctcct gccgagcgca gcataccagc ccttttccca agtcctctct ggatttcttt
     2401 ctgtcctaca aagcacgact atgatgaatg ataatcgcac tgtctacgca tcgcccaacc
     2461 ctgacgtaca tatgcccacg ccgacgtgcg tcgagtctgc ctaaagtgct gacgggcatt
     2521 gttcagcatg tgcaactgag accccatcag cattggaggc tgcattgttg acacgacaaa
     2581 taccctcaag cggccagctc agcccagccg agttcggtaa ccgttttcca aaacattcaa
     2641 aactatcccc aagactggga agactgcccc taaagtatca gccttgggag tctgggacac
     2701 ctcagccact tctgtcgtgg cgtccatcct cctgtcccaa attaagcttc atcaggtccg
     2761 agacaagatc gacggccaga cgcaaaaaga gcacgacagg atctccagag taatccatag
     2821 cgtctcggta tatatcacgc catacactaa aagcctccat ctcccagaaa gaaaagaaga
     2881 agaatacaga ctatctatct cctgttcggg cttcaccaga ccacgtcccc ctgccaggtt
     2941 ttcaaccact tttcctcccc agcaagttgt actcctccaa cggactccag gggaaccttt
     3001 ttccccgggg gccgaatcat ggtcgccgac gggcccctct ctctctccca ccgcagattg
     3061 gcagacccaa tctcaccgca gtataaaatt agcagttggc ccagactaac ccgagtggag
     3121 tagtaggccg accgggggcg cacattcgag aaagagtggc gtctcgactc gattattaag
     3181 ggggtgaaca ttgcccacgt aaacacctgc gtatatagcc agactactag ttacgtatgg
     3241 atgtccacac tgactagtta actaaggagt acagcttatt aattatagct gtaggagatt
     3301 tatattgaat atgcactcat ttactatagt atgtacattg tactccgtac tgtaacttct
     3361 aaaggcccta acagaatccc cctcgccaag cacacccact acccccgttc tggccaactt
     3421 ctaattgaga tcagcgccga gaaccaaacc ctcatctctt ttaagatctt cggggagggc
     3481 ccctccgcaa gaagttctgc cgaagtaact cagtccataa gtacggagta gtggagagag
     3541 aaaagaacag cgccgttgct tggggcgaaa gtggctcgac tcgaggctgt gattcggtgg
     3601 tttcaacggt ggatgtggat ttgtgtccac ccctgcaaac tcggaaagtt agaaggcttg
     3661 ggttttggcg aatggaattg agttttaata gttattcttg taatgaaaag ctacattcat
     3721 atatcctact atcagatctc tcctggtttg tcttcattgt ctcgtgcagt aaaggagaga
     3781 gaccttttag gggatattat atatatcagc atcttgcttg tcgagttgac ggagaaggta
     3841 actggaatcc gcctcaaaaa gcggtagcct tgtgtagatc atgatgtcgg tatcgactcg
     3901 agaagcatcc attcaaagca tcatactatc acccgtagag acttaatttg gcaagttagc
     3961 tgacgaacgt gcttcggaaa cagtcgcagt gtcgaatgtg gtaactttta tataggtgta
     4021 tctatcgatc gttgtcacaa gaaaaacttc atgttgtgca ttctatttcc tgcttgctaa
     4081 atcacgtaca agatcatgta tcttcctggt tgcgtttatc aatctcccta gatatagcac
     4141 atgcgaccca ttctcagcaa gtggaaccat aagtctccaa atcgcagcgt ccctcccctc
     4201 tacatgagaa tctttctctt tcccttcacc tcttctatca gcagcgtact tggcaggcct
     4261 gtgatcgcct cctacccgtc ttggctcgtt ctcgttctct taagacttgt taagcctccg
     4321 ccactccaca agggcatcat cacacatgcg cgacattgag taggtgtccg acataatctt
     4381 cagcactggc atgtcgacgc ccatctctct gaggaaccat tcacgaatgc ggatggctac
     4441 gagagagtcg atgcccaggt tagccacagg catgttgtgg tccagctgct cagggtcgat
     4501 ctcgagcaag ttacccaggg acagtgcgaa gcagctttcg agtatgacta ggcactcggc
     4561 agggtcctcg gccgaggcga gctgatcctt gacactgaca gacccggcag cttgctctcc
     4621 gctagagtcg tcctgcagct gttgctggcc gatgtagcaa gacaaccgcg ggtcgtcgcg
     4681 ccactcaccc tgaaagactg acctgatgcc cgtgatgagc tctgcgggct gggccgagcc
     4741 aggacgtcca caaactatgg cctcggccag catttcgtgc aggtccgtct ccgactgcct
     4801 gtcaaaccgc ggaaggatgg ccttgtagat ggtttcagca tgctcggaat cacgccggaa
     4861 aatataccca aagcccgtca ggatggcaat gtggatgaca gagccagcga gcccacgctg
     4921 gagtcgttgt tgaacaagac tagccatgta gtggttcgcg gcagcatagg cagactggcc
     4981 aatgcttccg acaatcgatg tcgtggacga gaagcacaca aagaagtcca actgttcatt
     5041 gccaaagagc tcgtcaaggt tcttggatcc caccatctta ggccccaaca cagcggcgaa
     5101 atcctcccag ggcaaatgat ggaaaagacg gtcccgaagc accatcgcgg cattcataac
     5161 gcccccgaca ggcggcatgc tagacttaat atcgttgtag gcagagcgga gagagtccat
     5221 gtttgtaatg tcgacggcca ttggtcgcac ggtagctccc ttgtgcgaca agtagttaag
     5281 cacactagga gagatgttgg ggtttcggct ggtcaagacc acgttccggg ctccgttttc
     5341 caccatccat aggcacaccg agatacccaa gtctccagtc ataccgcaaa ggaggtatgt
     5401 cttgtcagga gcaaacagcc cacggtgctc gagagggcgc accagggcgt tgatggtatc
     5461 ggcagtactc caatcaatca aaactgcggg gcccagttcc ttgcttgtca cggttgagac
     5521 cttgtcgatg gccacaatct caacagactc cgtggggacc tgcaggccat cgtggatatt
     5581 ctgtttggcc aggatgcgga gttcagggag gattaaactg gcggttaagc tcgcgacgtc
     5641 cttgttcacg atggccgagg caggcaaaga agcatgaata aacgcagaca atgccctgtg
     5701 ttcttggcgt gctaggttga tgaagctctg caggcccttg gggcggaaat cctgtaggtc
     5761 ttccttattc gcgtaaggat ggatgaaatt gacatccgaa gtcatcgcca tatccgacgt
     5821 ggtttggaac acggcgacgc tctgctcccg ggcaaccacg tcgatcacct cgcggaggcc
     5881 atgcggtgcc ccgtgaatcc atgtaggccc tttcaagctg ccgagaaggt gttcagcaag
     5941 tgcgcgtacc aggaagagat gcagatgtgc ggtatattca gcagtcgtct tgtcatcctg
     6001 ccagcgatat aagatgtggt cttcggaaac cttgaccact gagctgttta cagctgaaag
     6061 agcgagggcc gtgtctccgg aaaccaggtc gcgaccgatg cacacataca ccggcccgta
     6121 ctcatcacag gttatggtgc gaatcgaaga agccaagacc tgcaggcaaa tctcatcttt
     6181 tgtggctccg ccaaaaggaa tagtctgcag ctcgaatgct ccctggcgct catcgaccac
     6241 cacagccacg tcctcagacc caacgctggt aagctgagtg acttgtcggt gccttgcggc
     6301 ggatcgacgg ttaagagtgt caagagatac caccctgggt acgtagaggg cgccctcttt
     6361 cagggcaagc tcaggctcct ggacccagag cagttcgtcg ttcttggatg ggtccaggaa
     6421 ggcgagacga agaagcatac ttgccagcat agacggatca acagacgacg gttcgtcaac
     6481 gtcgaggaat tggagcctga gatccatgcg ttcagctcgc aacgtgctcg acagtcccag
     6541 agtgatgttg gcatcaggat cattgcctga cttcgcaccc gaggtcaccc atagaaccac
     6601 ttcggctgat tccatgacgt tctgcaaccc tctgaatctc tttgagttca tgtcgcggaa
     6661 cacagggctg tccagatcgc taaggcagag tacagctgct cccttcggta cctcaatgcc
     6721 ttcgagtcct ggcagtacgg tgacagtgtt ggaaggagca gcagcttgca agggtttttg
     6781 gatctgggag gcaagttctg aagttacacc accaccgacg atgaggatgt cgcccagcgg
     6841 cggaagggct gttggagcga cagcaagcgg ttcgcggagg agctgtaccg tctcgtcgac
     6901 tgcctgtgcc acaataacag agcagaagga aggcgtcgag cttatttcaa ccccagagaa
     6961 gccgttggcc ttcagcagct cgtcccatcg ctcgaggctg acggtaggtg cccagactct
     7021 cccgtcttct atgcccagga accatccagg cagtgttgac ataaccagct gtgtaggcag
     7081 gaagtctcga gtaatctcca gcagcaccaa gcggccaccg ggttggagga gctgtctgca
     7141 atgacgcaga gtctccccca gacttcgtgt cgcatgcaga cagtttgagg agatgaccat
     7201 gtcgaacgtt ccttcaggga atccctggtc tactggatca ttttcgatat tgagcgtctt
     7261 gaaagagagc ttgctgctat gctgaccgaa cagcgtgcgg gcgttttcga aaaagccggt
     7321 ggatatgtcc gtgtacgtgt aggacgcata ttgattcccc aacgcatcta gaactgcccg
     7381 tgtagtgcca cccgtgccag ctcctacctc ggcgatacgc atgcgcggat attgatgggc
     7441 aagctgcttc acaaaaccgg caagatcatg gttaccgtcc cgggcaccga gtccttccac
     7501 atacagacgg tcgagcatgc cgtcctgtgt aagcactctg aggggaggag tggttccgcg
     7561 gacaatgccg accagattct tccccatggc gtgaagaatg ttcatatcgt tgttgtctga
     7621 cggttggctg gcacgccatt gctgcaccat ctcgagcgtg tcatctttcc actcagcgcg
     7681 aatttctgga tgctccccag cttcaatccg ggggagcaga tgctcaagga cccaagtcat
     7741 catgtgtttc cggtacttgc ccatcagcat cagttcctgg ggcaggatct tcttgcggag
     7801 ctggcgcagg tagaagtagg ccgtgcgcga gagctgctcg tatagcaccc agtccgcttc
     7861 cgagagcttg gtcttgatgc tgggctcgat tccatagctg acatcccttg cccatgtggt
     7921 gcctgcgtag agccaggggt cccggcgttg ccccacggca ctcaggtgaa ttccacggat
     7981 ttgcacttgg gtgcgcgcat ttgctgcatc gaacaggtct acatcgcctg tcagagtggt
     8041 tttacccgtt gaggtcacgg tagcgtcggc tgtgaggaca gtggcatgcg actcggaggg
     8101 catcatgttg accctgacac attcaacccg tgtcggcaga tagatggtcc cgaggcgacc
     8161 atctcctggg aacgagaagc cagccaatag accttggaag gcagtatcaa cgggtgcggg
     8221 atgcacgcac tcgcgcatcg aagagggctc ggaaggtgat gacacggtca ccacggcgcg
     8281 attaagccgc cggtgcatcg attttgcctg aaacaggtcg gcgtagttga agccttcctt
     8341 ggctaggttt gagtacagtt gctccatgtc cagagcttcc atgggaagca gaggtgtttt
     8401 ccgtgaaggt aacgtgtccg tgctgggctc accgagccag agccttacac ctccggtaaa
     8461 atgagctgtg agaccagttt gaggggcatc caaaggctga accgagtcga cagcaccgct
     8521 ataacaggca acttcggctg taatgcagtc atccgactgg gcagtaacgc gaacagtgaa
     8581 gacaacttca agccccgagg aatcttgttc gagccgcatg gctcgcacaa tgtcaatatc
     8641 gtgcaattcc acgagacgca gtggctgccg gtcatctacc aatcgagtgg cggcctcgta
     8701 agccatcgac aagtagccag atgccggaaa taaaacttcg ccctgaattc tgtggccagc
     8761 cagccagggg agctcattca gcctcaggag ctgtttccag tgcacctcgc gcttgtcacg
     8821 ctcgccatga gtgacagaat gacccagaag ctcgtgacga ggttggctct gagtacggaa
     8881 aatacgggat gttctcgact ccttccagat gaggccggga tggtcccacg agtaagccgg
     8941 gaggcctttc agaacggcaa gcttcagcgg ctcccggcta gggaaagccc tgcgtacgcc
     9001 gtcaaaggtg atcagggggc gcgacgacgg gaaagacgtc cacagaagcc ccaaagcatc
     9061 tgagaatgac gtgaccgcat tctggccacg ttttagaact cccgagtacg gaagggagag
     9121 acctgtcagc attttgatag tctcggcgct cggccctttg agagcagggt gtggtccaac
     9181 ttcgagagca aggtcaaagt actggtcttc gttcagggct ctcgccagtg cttgactgaa
     9241 aagcaccggc tgggtcatgt tatcgaccca gtactggccc tcgagaagca aaccatccgc
     9301 ttggttgaat gaccggctgc ggccatccga tccccaaaca ctcgagtacc accggcactg
     9361 ttttccgccc ttctgaactg tgactccaca ctgcttcatc gactcgagat aaggaatagc
     9421 gcatggcttc atgtgatgag aatgatatgc cgtgtcgacc tgcagcacgc gggcaaaggt
     9481 tcctttttcc tgcagccgag cgtgggcatc ctcgatagct tcagcatcgc ctgccaaggt
     9541 gcagctcgtc tgagagttgc tggcagctac ggtaagcgtt cccccgaact cgctacagaa
     9601 agtagtcgct tggttcaagg acatacccac cgccatcatc ttgccgcgct tccctcccgg
     9661 cccttgcgct aggtgggagt ggaaacctct gtagtatgcg acccggatcg catcagtggc
     9721 atcgaggtat cccgcagcat atgcagcgcc aatctctcca gacgagtgtc cgacaacagc
     9781 ggagagctcg acaccggcgg cacgcaagac atcaactaga gcgacttgaa gagcagtgca
     9841 gagaggctgg gatacaattg cctcgccaac gcgggaatcc accgctggcg cgtcaagttg
     9901 gtcaactagg gaccagtcgg ggcgatcttc aatgggaagc gagttgagag cccgctgcat
     9961 ctggtctata gcgctgcgga aaacactaga agcgccatag agctcctttc ccatggtagc
    10021 ccactgcgcg ccctggccag tgaaaatgcc caaaatccgg ggcggcagca cctcggggat
    10081 ggtggcggtg cgcgagctgc tcttgagaga gtccttacct gcctcaagct tctctgcaag
    10141 ttgctccaca gatgtagcag agaaggcagc tcggaatgga aagtctgtcc ttcggaatag
    10201 agtataggca agtcggcgca gatccgcgtc gggatgcgcg cgaagatagt cggccagcgc
    10261 tccagcattt gccgccaaag ctgcgcccga gttggcagac aggacgaaag gtcctgcgcc
    10321 caggggtttc agtgtgttac cgttcagtgc gtagccgttt gtgagggagc cagcgccatc
    10381 ccagctctct atgatggcgt gggcattcgt gccaccgaag ccaaagctgt tgacactaac
    10441 acggcgcgga tatcctttcg agacagcggg ccaaggagtt gtctcagtag gaatgcgtag
    10501 gtttgtgtaa tatggtcgga tcttggggtt gagatccttg aaatgaaggt ttgccggaat
    10561 ctggccgtgt tgaactgcca gcgacgcctt tagcacacca gcaattcccg cggtgccctc
    10621 agtgtgtccg attactgttt tgatgctgcc gactatgagc tgaccctccc tctcgttagg
    10681 gaagaaaaca ctttggatgg cccgggcctc gatagctagt acgtgtcaga ataagttggg
    10741 aggaaagacg cgaagaaaaa tgcaagacgc cacttacggt cacccgcctg cgtgcccgtg
    10801 ccatgggctt caaagtactg tgggcgatcg gattcacgag ccgggttgag cccgcacctg
    10861 gcgtaggtgt cacggataag tcgtgcttgc gactctgagc tcggcattgt gatgcctggg
    10921 gaggtcttta gcgcgtcaca agggaaaatt aagcagggtt aagcggacat acctggcgtc
    10981 ttgccatcgg agttcacgcc agtctctcga atgatacatt caatgtgatc accgtcggcg
    11041 atagcttggc tgagtgtctt gaggaagacg gcggcgaagc cctcccctct ggtgtatcca
    11101 tccgcagctg catcccacat gaaggatcgc ccattgggtg acagcatgtt aagctttgcg
    11161 tattacctgt cagcttgtgc taggattctc ggcaccgggc agctgtctaa caaaccttag
    11221 attcgctaac gaatggctcg ggcccaatta tgagatttga gcccgctgcg actgccatct
    11281 cggcctcgcc atttcggagg gcagaaactg cctggtgcag ggcgaccagg ctagacgagc
    11341 atgctgtgtc gatggtcacc gagggacctt tccagtcgta aaagtacgac acgcggttgg
    11401 ccaaaataga tgcggcagta ccagttccgt ggtactgggg caggctgtcg atgccccgga
    11461 tggcagtgag atggtaatcg aagctcatgc atccaacgaa aaccgcggta gttgaccccc
    11521 gaagctgttg catcgagtgt ccagttgatt caatgccttc atacacagtc tcgagtagca
    11581 agcgttgctg gggatccatg gcctcagcct ccttggggtt aatggagaag aagtcacgat
    11641 caaaggcgcg agggtcctca tcgagaagat aggcatgctt gacgttcgta ctctatttgc
    11701 caaaaagtca gatatacaag ttcatgttca cacagcaaat atgctcactc catggtgctg
    11761 gctgtctggg tggtggaatg ctttggtgtt gaaacgagtg gctggtattt cctgtaagac
    11821 gtctcgaggt ttctctagga gctcccaaag cttagatgga gaggttgcgc caccggggaa
    11881 tcggcagctg ctgcccacta tcgcaatggg ctcgcgtgca aagtagggag ggttgccctc
    11941 agtctctatg ctccccatgt cgaaggctgc gatatgggta aaaggagggc ttcaaatcga
    12001 acagatagag cagcccaaca agagactggg aggttgatgc ttcctagtcc aggaattggg
    12061 ggcatagcga gggctaggag atatatggta aggatgcgag gcaacggcct cgagcactca
    12121 atgccaaacc cgaacctcta gcccgataag cttaacatca tctcccaccc gacgccggag
    12181 ccttgaggca cactgtaatg cccgagccgg agtttggtgt attcgtcgta tgtcggcacc
    12241 ggtggttatg cttatgccgg tatttctgcg atgccgcacc tccggcctcc gattcgctct
    12301 accatgtcgg ggctctctgg attatgccga ctgctgcccc cgacactatg ctcgtcgctg
    12361 ggtccgaggc gtcattgggg gccctatagt ttggtattcc aaatgggttt aaatccacaa
    12421 aagtaaacat cgtgatatag gctcgtactt accttcatat gctctctccg tgcccttccg
    12481 cgtagctcac ttccatcatg cctactacta tgcaggctct tgttggtgct gaatcaggag
    12541 gctaccgtct ggctgagaat gtcgatatcc ccgttccaca acgaggctcg atattagtcc
    12601 aggtgcatgc agtcgcttta aacccacgag acgcgaagat tgttgatttc tccaatgccc
    12661 ccgggtccct gggcggctgt gactttgccg gaactgttaa gaaggtgggc gaaggagtga
    12721 cgcggttcaa ggaaggtgac cgtgtactcg ccgttacctt tggctcaaat gccttggaca
    12781 agacgaaagg tgcctttgct gagttcgcct tggccgaaga ggacatcagc tgccgcatac
    12841 ccgaggactt ctccttcaca caagcatgtt cgatcggact ttcgatggct acggccggtt
    12901 tagcaatttt tcaggccccc ggacttgagc tatccctgca tgggggaaaa ggggaggccg
    12961 tgctggtctc gggaggtgct acggccacgg ggactatggc aacgcagcta ttgaggatgt
    13021 gagccgacct tccagaccgt tttcagctga atcctcactg acctgttcat ccccagggct
    13081 ggctatacac ccatcgtcac ctgctcacct gccaacaacg ctctgtgcca gtcttatggc
    13141 gctgcagcgt gtttcgatta ccattctccc gcctgcgggg ctgatattcg tgtgcagacc
    13201 aacgacagtc taaggtacgt cctggactgc gtcaccgaca ccaccaccat gaagatgtgt
    13261 tatgaagcca ttggttcttc cggtggcagc tacatcgcac tggagacaat cgccaccacg
    13321 gtcaagtaca cgcgaaggga tgttcgtgct gactggtttc tggccgatgc catcatgggg
    13381 aacggggtcc aaatggcggg aacatatggt cgggctcctt cacccgagct taggcggttt
    13441 ggcaagcagt tgttcgccct ggctgaaaac tggctacacg atgggagcat caggcatcat
    13501 cccttggaaa tccaagatgg cggcttggca aacatgcctc aggctcttaa cgacatgaaa
    13561 cttggaaagg tgcatgcgaa gaagctggtt gtgccaattc ttggacatta ggcgtgagta
    13621 tatacatcaa cggctcgcag aatagatatt ttgaccacga gttctcaaat cttggcaagg
    13681 acgggagata tctggcctgg atggatttag cgtatgcgag atcttcttta gttcctcgcg
    13741 cggaaagcgt agttttttcc atgcaatttt caacacaaga agaaattttg catgtttcaa
    13801 atgaaatttc catattccta tcagtttccc ggttgcctgt ttagaccaat tcgaagaact
    13861 ttgttcaaat tacgggatgt cttcggatcc tctctcacca ataccactac agaacgcatt
    13921 atcccctgtt tcccacgttt taaaccctag atatggactc tttaaacaac cggagaaagc
    13981 agtaggcagg taaattcctt cgtctgcatc tagtacgatc aagaaggtga accagaatgc
    14041 tgctgcttag aggtatccta ttcgcggccc tccccctggc ctccaaagac gcaaggacga
    14101 gctggatata tgaggctagg tgctcctgca gccatagctg tcagagtaga ctctgcaggg
    14161 cctaaaagag tagtcccacg agagaccctc ttgagtaatt caggcgaccg tgagtctaac
    14221 tctgggtctg gtttagagat catggcccgt gacattaaaa tattgcttga tcaactggaa
    14281 tctgcttatc ccatggatct tcaattttgg aagcatagaa attagctatt tgcccatccg
    14341 ctaacactat tcggcgcttg gagacatatg aactctccat gacgaatagg ccaatgaaat
    14401 taatgataat atggctgcgt agtcgtatga ttgcagtatg tttactggct aatcagagtc
    14461 ccaggatcag aagaaggata tatgatacgg atgagaatag tgactgctga gtgaatcaaa
    14521 gtttggatga agcacgtgtt attatcatca gcggctttat gggtattgaa atcatcatga
    14581 gtacagccgc tacttcgata tcacagaccc gaggcagcaa gataagtgca tactcaatag
    14641 aaagttgtca gaagatgttt aaatataggg tttcttatcg gtacttcaga cgattcggta
    14701 caaaatcgat ccttcacacc cagcagaatg gaaatcttag tgtctgatgc tgaagtttcc
    14761 tgcctgaact ttgcccaatc ggtctgcata ctttgcaaat tcacttttgt gggggcggaa
    14821 ggagcttaga taggcatttg ctgtatttgg atagtgtgaa agatcttaga acgtgtgaag
    14881 tgaatgaatt ttggggaaat tctccgtttc cgcgggcaaa agtggttacg aggctggaca
    14941 gatatctagg ctaccgagca ttggcatgta cttcaagtac atatgtctta gtgtttggtg
    15001 gaatgcattc aatataggta tcaggaagga tgtaacctaa ctccaggcat gatcaacttg
    15061 cacgtatcat gcaaaagtac ggcgcaacct tgggacacct atctctatat attactcgct
    15121 gaagcgtgaa gatgtggctt acatatatca atatgcatga tctagatatt agctaacgtt
    15181 gccccggtgg ccgggtggta ggctcgacta gatctattcc gagaaactat atgaacaaac
    15241 cccaaacaga gcgggattcc tgccgattta tcctttcgca aaggcgcgga ccattttgtt
    15301 tacgttgtat tttggagggt gcaagcctgc gcgaggaagc cactggacag atccttaagg
    15361 tatggggcag aggccgggag ctgaatgcgg ggactacgat gataaaagag attatcctaa
    15421 ctaagtacga ggctaagatt cgacatggat gacccatgcc aatgaaaggt atcctctgta
    15481 gggaattacc ggctgcacta gataatctta cacatagaac atccgcttca gcacctcaaa
    15541 acatccggtg caagggccgg ctatgatttc acgggcgggt tatgccgcct atccagaggc
    15601 aaggcctgaa gggaaggggg taggcacagt tctcattggt attactcttt tttctcatac
    15661 tgacgctagt gatcctgctc ggaagatcct tcgaggatag tgtgcttgat aatcgaacca
    15721 caattgtacg tctcgagccg ataacgaccc gaaggatgat tctgcatgtg cataacgcat
    15781 ataagatgat gaggctgcga ttgggatgcc aaggttgctg caagaagagt ggatctcaag
    15841 tacattgcct cctttcagaa ttactaaacg ccaattctgt ccccgtatct agtgtgtgta
    15901 cacggttttg gtggtgataa tgggcgcaag tgacgccaat ttggcccccg aaacgtgaat
    15961 acatccaact ccatctgtca ctgaggagag agccctaaca catggcttat atacatcctt
    16021 gtagcccacg ccatactgag cgacaaagct aaacgaggca gcccccaccg gaagaaaaag
    16081 agagattcgc tgacatataa gaggccaggc ccgaatcaaa aggaaggtca gattgatatg
    16141 gagaagcgag aacgtgtata atgtcacacc ggcagtcgtg tgaccgctgt cgacagcaaa
    16201 aggtgagatg ccttcgagat gaggctctag gaggggaaag caatccagtt tccccaggcc
    16261 gatcttccct gtctccatgc gaacgatgtt tgaaggcagg agtggactgt gtttacagct
    16321 gtacgtattg gcaatctgct tctgcaactc tcgcttttgt gtcgatggag cggtataagg
    16381 cgcagtttga ccaaggtctt gcattgactc tcattcatag tgaaacaaag atccaatcgt
    16441 cgctctgttc aaacatccat ccgaagagac accgaccccg ggtctaggaa tggaagcaac
    16501 gcatcgtggc tcgaacaagg cctagctcgg ccaatgtatc agggtgggcc gttcctgggg
    16561 gccgacttgg gcgacctagt aggtcaattc tccggagttg gcgagggcgg acctgtcgct
    16621 agcttcaacg gctgggatgc aaacctccag ccattttcac caactttatt cagctccttg
    16681 gtagcaccag tcgggactaa cacgggtccg atttccactg ccccgtcgac cactgatggc
    16741 ggccatgata gcgaagaaat cgatgacaac agagacccaa ccgatgcctt atcctcacag
    16801 ctaacgtcct tgggtcaaag ggccaggcgg gctatgcgcc gtcttgtcct cccggaccgt
    16861 actcccctga ccgtttcgtc acccgaggtg aacgaggcat tggaggacac taatacccta
    16921 atacgcatca tgaataagat tactgcgccg gatcgtgacg acattaccat cttcccgact
    16981 accaccaatt attcgctggc attctcagca ctcgcctgcc accaacacct cgtggccttg
    17041 tttcgggcca tctgtgacgc tatccatcgg tgcttacagt cccaaaaaga gccacggcaa
    17101 cgacacaatc gaagcggaca gaccagcgac gtagggccgt cttcagtggc ccaattcgtc
    17161 atggtgcttc agctgcttat gcacctcatc aaccgcatgg accggagcct gttccaaagt
    17221 acctcgtcaa tgcgacatgg cagcaggatc tcggtatcca ctggcagtca ccttgccccc
    17281 gtcacgccga gcacggccaa tcatgttact ccggacccca caaggatcga ggcggctgca
    17341 ggaagctcag taccaccagg gggccttctt gttcttgtgc aggacattgt ggagacaatc
    17401 ccaaacgagc acgagaagct gagacaagtt attcagaagt tacagacaga gatggaacac
    17461 tcggagcttc actgacggaa agaaatggga gtggtttaga cattgaagat attatgctta
    17521 atgtttcacg agaatatcaa ggcacactgc gacgctgtga tcaacggagg actgacttcg
    17581 aagtaggaga ctatcgagaa aatacacctt gcaattgaat ttggaaattc cggcaacgga
    17641 taagctgtga aatgatctcc actgactaca atcttcaata aattgcatca acccatcagt
    17701 acaaattagg caaaaggcgc gacggctaaa gctgagccac ggcctcgcgg cgaaacttgg
    17761 ctagacccac atcatcacca tcggtaaata ccaacttccg gtcggattct tgtcatctgc
    17821 atgcataatc aggccagaga atgacgaatc tccgtccgga tagactcatt ggccagggtg
    17881 agattgaaca ccttcaggat tgcaggctaa taaggccaca gtggcccaca gccccgccca
    17941 tggaccgggc cgcagcctgc aaatgatggc ttgacgcctt cggggtctat ctacacttta
    18001 cagtactgca cccaacagtt tgggccccag tcataacccg aggaaatcct gagacgacac
    18061 gaatgcgcca gcacagaaga atccggcagc ctgagacgag atcgatacct tacaaatcaa
    18121 gcgaagcaga cctcaaacgg gcaaaggcta aggatccagg atcagtggtg acatgaccta
    18181 tctctatacc acacggtcta tatattcctg gcttgtgctg ctcccttgta aattggtgta
    18241 tggtactaca tacctatgtt caagccgaat acccaatcca tacgctctgg gtctattcag
    18301 caccttctat ttcttctgtg caagtaagac gtgttcatca gaatcccaaa aaatcccatc
    18361 ccgttcgatg tcagccttgg caccctcgga aagccgttta aattcctcct ccgctcctgg
    18421 cgttccgctt gcctgaagaa tcatcttggt agatgtggtg cacgaccata ggtaaaccga
    18481 gttgacatca tccttcaact caggcccact tttgattgta ttgaagattc tctcggacac
    18541 gttttgaagg cggggatgag cttctgccgc tttaacaaaa gcagcgggga cactgacggt
    18601 gtcagtattc ataggaaagt ggcgagatgg gacactgaac ttactctagc tccataccct
    18661 tagtttccat gtgctttcta acaagctcgt tcatttccct cacatgggcg ctggggaccc
    18721 tgccggccca agattcgcca tcaagctcat cccattgaat ccaccctccg ggtcctttgc
    18781 ccaagccaca gtcagaatac gctcaaatcg agctagaaat cttacttacg taaaagttga
    18841 gcaagattgt ccactgccgt gttcacgtca ccctttgaca acgcagacac caacaatctc
    18901 acgtggacca agtcatattt ccctttcagt ccttctggga caggctggag gatgttgtag
    18961 acatcgtaat gaaagttttc cgggtggaaa gccggaaagt gggccggtga catatcaagg
    19021 ccgtcgtatt gacggggttg gccgatcgct gtcgggatag ggtccagatg ggcagccaga
    19081 gcgtcgagcc agatacttta acattcggtc agtaggcttg aagaaatcca aggggcagaa
    19141 gactcaccct gtgcctgttc ctacatctgc aattttgaca atagtcgagg gatcgatggg
    19201 agcgtgcagc aattcatttt cgataatgtg gaccagaact cggtgttgat tgttcagcct
    19261 ggagattgtt gaaggttagg atactgttgc caggtgatca tagggagcct gacatacctg
    19321 gcgcgttcct cgtcgccagg cttcaaatag tagacgcttt cttggggctt ttcggatgcc
    19381 attttttggg cttctctatc ggcgggacga aatgcctttg tttggaaact atggaaacaa
    19441 ggctattgga tagcgagaga tataggggga gggagagaga tataggggga gggagagaga
    19501 tttgaggagg agaggagacg taacgataaa ccgaaatatc ccttaaatga gggctgggat
    19561 gtagaatgct tcatagattt ttctccatag acgtgactgc agtgatcgtg agagacaccc
    19621 atagtcaagc cattccgatg aggcctccta aatgccggcc aattccaccc gagaaccgac
    19681 tccgagcatc gcagacctcc gattatcaat gatagtctaa ttcggttggt gatgtgtaga
    19741 gtacggtttt catacgtata cttcctgtca taatcagcac ctaatcatgc attggatgcg
    19801 cccttggcgc attagcctcg ttctagttct ccgattctta aaacagaggg tcttttgtgg
    19861 ggcgttcggg gtaatttgct ttccgacccg catttcattc gctcagccgc acgcatgttc
    19921 ctacgccgat cctggccgcc gtttgcaaaa gtcctaaact actgcgcaga agcagggtac
    19981 aagctgcttt ataacatctg ctgatcaatt attaatcgtc ctttttggtt agtcagttat
    20041 gatgtagggt agctagtcaa ctatcaacta gttaattacg ttacaatgta ccttgctaag
    20101 cgtttgttgt ccttaactaa ttgtccatat gcaagggtct ttgtcggagt cggtgcgaaa
    20161 gactttccgg ttaagcataa acgctgcata aggcactcgg tttctgatcc gcccggtttg
    20221 aagaatctta ttccacggaa gccagggtat agaatgctta gagtagttca taacttcgac
    20281 ttattaatcc aaggtagaaa ttgttagcag actacagttg ctcttaccaa tcattatttt
    20341 ggttagttgt tgagatccgt gcattggctt tccgatcggg gacaggggca gatctcagga
    20401 tagggtttct tcataaatca gacatactca acttgggcga cttttaggaa ttattctttt
    20461 tattttcata cgacagtttg taccgtagca ctcgcacaat tcgagcgaga tggctgaaaa
    20521 ccaggtcgac ccaaagagaa atttgcctct ctatggagca gccgacgagt ctacatcagc
    20581 gacggataaa gaggatgagg ttgagaatgt gaggcagaat gggtcagcgc ctcccatcga
    20641 agaggccagg gagtcgaatg aggctcccgc agcagacgag tatcctcatg gtctgagtct
    20701 attctttatt gtgttggcca tcatgcttgc cacgttcatc atatctcttg accaagtgag
    20761 tggctctata cccttttaca atctatctgt acttactcta actttgctag acaattgtcg
    20821 gtactgccat ccccaaaatc accgatcaat tccacggtct cgacaaagta tcatggtacg
    20881 gctcggcata cttcatgact ttcggtggct tccagacctc gatgggcaaa gcatacaggt
    20941 atttcagcct gaagacgaca ttcctagtct ccctcttcat tttcgaaatt ggaagtctca
    21001 tatgcggcgt ggcgccaaat gccaacgcgt tgattgctgg tcgagcgatt gctggtctcg
    21061 gcggtgcagg tatggcgacg ggtgggttca caattattgc cttctcttcc gagcccaaga
    21121 gacgaccttt atttacgggc ttggtcggat ctgcctatgg cttgtctgct gtagctggtc
    21181 cgcttattgg tggtgccttc tcagacaagg tttcctggag atggtgcttc tacatcaacc
    21241 tgccagttgg aggtcttgca gccgtgatca ttttgatctt cttccactcc ccgagtggtg
    21301 ccaagccggt aaaggcacca ttaaaagaga agatcctgaa tatggacctt gttggcgtgt
    21361 ctttgctcat gtgcctcatc atttgtttca ttctggccct ccagtatgga ggacaaaccg
    21421 aatcatggaa ctcgagtaaa gtgatcggtc tactcgtcgg ctttgtcgct attctcgtcg
    21481 ccctgattat ttgggagtat taccttggtg agcgcgctat gcttgtggga cgtttgctca
    21541 agaagcgtgc tctttgggct ccgtcaacat acatgttctt ctttgccggc tcttatttca
    21601 tcctcctcta ctatctccca acctactttc aaagcattga cgacacaagc cctattgggt
    21661 ctggggtacg gaacttgcct atggtggtca ccttcagtat cgcagctatt cttgcaggcg
    21721 cgttcgttga aagaaccggc attgcaacac cagtcatgct tgtgggtgct gctatcgcaa
    21781 cgatcggaac tggcttgatc tacacatggg atatcggcac cccggctggg aaatggattg
    21841 gttatcaaat tctcgctgcc ttcggtttcg ttattccttg gctgatcccc atgaacattg
    21901 cccaagcaaa tgcggacgcc caagatatgt caacagtgac ggcttatatt tttcgtgagc
    21961 aagcccctat cagatgtgtc ggagactctt caactaatct agcaatcgga ttcagtggcc
    22021 caaaccctcg ggggagcgtt cagtgtctca gccgcgcaat cagccttcgt gaacaccatg
    22081 ctcacaaaaa taaaaacaac agccccagat gtcgacccca tggctttaat cgcaacaggc
    22141 gcaacacaga ttcgtgcaac gtttcccaac gacatacacg gtgttctact tgcgtacatg
    22201 gcaggcctca aagcaacgtt cgcgatttca gtcggaatgg ttggatttgc ctgtctaatg
    22261 ggtcttttca ctccctggaa cagactgcat ggctcagctg ggggagctgc ctttgcttga
    22321 gcaggatcgt tccagcatat cctaagagag atccctatga tggctaagcc ttttatggtg
    22381 gatggtcaag ggacgtctcg actttatatt tcgattttag agttttgctg cttgggtttt
    22441 agaggcttgc agtttatggt ggtgatgctt ccatggacta tggccgtttg ctttctacct
    22501 cggatcaata tgaggtctct tctttgcttc tcgtttaaca gatatcttaa gacaagatta
    22561 attttcccgg gtcccttcgt gtttcgagtt tcttatacgt agatggtttc aagtatttat
    22621 ctatatttat aatctgactc cggtgatggc gatggatata agactgtttg atcgattcca
    22681 gacctgatga cgtttgcaac tagttatggg ggtagtcacg attgagtgaa tcattgacag
    22741 tattttagat attctgaact tcagaatact acggctttgt ttttagattt ttttaagtga
    22801 agatatatag aattatacga tattagggta ccaagtcaac aaatcgaagg cgattcctat
    22861 tcctcccaac aggggctctt tgtggatcga ttcaggggct ttttgtggat cgattcctat
    22921 ccttctagat ggatcagacg actctctgag aaagttggcc acatacaatg ctacactata
    22981 ctagcatgct atagcattaa tcatctcgtg actcacaatg gttagaaatc tgtatactgt
    23041 atgttttact gtagggaggc taaggtaacg ttggagatcg ggccgagaga tcggtggggt
    23101 tgataaggtt aaggttcttc ccgtccgatc ggtgcgagtc ggcgacgcca agactccggc
    23161 tttgcggctg atctccggac tccgagatac ctactgtaat gattgctgca aaatgtttcg
    23221 tatcgacttt tgtctacgag ttactacttg tataatatgt tccggcttgt gagaagccac
    23281 actggcccag tgtcttgacc acgatcattc tcctcctcca gctcaactct ttcacagaag
    23341 aacacaatga cggccagcac tctacctcgc tccgatgtcg aattcacaac cctcgatgga
    23401 ctcacattac gcggctggct gttcccagcc tcacagcgcg gccctgccct gatcatgtcc
    23461 ccaggcgtac gtgtccatat taccaactgc ttggtgatgg cttcgaggta cccattgact
    23521 gacacctgag tagttcaaca tgcccaagga tgccatatta cccgatattg caaagtggtt
    23581 tcaagagcac ggtattactt gccttctcta tgaccctcgc ggaataggcg ccagcgatgg
    23641 agagccaagg aatgatgtga gtgtggtaaa cccggggccg tccaagatgg aaacttatct
    23701 cttcaccctc gatgcctcgg tgtagatcga cgccagacag caagccgaac accttcacga
    23761 tgccgttacc tggttcaaag agaacccctt ggtcaatgag aagcagattg cgctctgggg
    23821 tctgtgtttt gggggtaatg ttacccttgc ggccgcggca tttgagtacg taaccccaat
    23881 cggtaccttt ctctcttttt tattccattc ttctctcttc ttccttacct tgcgtcttcc
    23941 tccgccagtg cccttgagct gaagaaaagt cctactgcag caagcgagtc gctgccgcaa
    24001 ttgcggtcgc acccctgatc gactcaactg gcaacccaga acgacgacag ccaatcctcg
    24061 agctggccat gcacgaccgc gccagccgcc tcgacggaga agagcccatg tatctccctt
    24121 acgtcaacga agatggcagt attcccaacg gcctccagct cgctgccgag atgatgcccg
    24181 ccctcgagcg cctcggcatt cccgtcgaga accgcatctc cgtccagacg tactataaaa
    24241 gcctatcatg gaatatcctg aacgtcgtcc agtatatttc cccaacgcca gctatgatgg
    24301 tgacacctga gctcgatgtg tcatgcccca cagaggatca gcttaactgt tttgagcata
    24361 tgaaggagcc caaggagctt gacatcttga agggcaaggg gcatcttgat tgggtatttg
    24421 gagatgttga gagcattctg aacagacagc tggacttttt aaagcggcac atggccttct
    24481 gaaccggggg ggggggggcg ggtttaaggc ggtggagttt agaagaacta ggtgcacata
    24541 tatattggcc catagtggca caacacatca atgacaccag gcatggtttt ggtgtaccaa
    24601 agaccgcctc ttgtaggaga aagcaccttt cctttcaatg atactcctcc gggggctttt
    24661 tctctagtag atcttacctt gttctaccta ggagacggac ctggtttgtt agctgtaatt
    24721 cccttttcag tatacaccgc aaagaaatag agacgaacaa aagcaatcca agaagacgat
    24781 ctgctgaatc tgtttgcaat ggacgtgtct gggtaacctt ttgtagccgc caaacatcct
    24841 tttctctgtc acttggccaa caagtctcag cgggaaggtc ggaacagtgt ggtgtattgg
    24901 aagtccttag gtcctgtgtc aaaatagccg cctgacgaga ctggacccgt gtagctttct
    24961 gtggacatta gtttcttttc acaactctat ctagaagctg gcgtgcgaag acaccccggg
    25021 ctatttacag attttcttta tccataacta cgcatgatct agatctgggt gaagcaagcc
    25081 atgggatgat tttattgtgt attgattggt tgtctttgtc tgccgtaagt gtagtgatct
    25141 tatgtgctgt cgagatgctt ctcgaatacg caccaaactg gcaccaccta tatcaccgcg
    25201 aacgtttaca tgtttcgaac tgacagatga aacatggacg atggccaaac caggggttca
    25261 gtctcccgat gctcgggctg actactggta taggccgtct ttccagccca tcacctctgc
    25321 ctcggccgca taagtttgag agtagtggtc catgagatcc tgtttggtgc gcccgtctct
    25381 caattttaaa acgacattaa gttctttggg gtggagggca atctcctgca cgaagccagt
    25441 ctctaagctc aggtcgattt cctttccctc gggcggcaaa atgtcaaaag cccagagtac
    25501 cttagccagg ccaaggagca ggctgtgctt tgctgaatgc atccccgggc atatcctccg
    25561 gcccgctcca aagtcccaag tgacccgcga agctgacgcc tctagatgag cagcatctaa
    25621 agtatggtcc gaccgcagcc ctaatgggtg ttgcaggaaa cgttccggaa tgaactcctc
    25681 aggctcatcg tagtcctcct cagagtggtg aatgttccag acgttcatga taatggccgt
    25741 gcccttgggg atacgatggc cattataaat gtcgtcctgc gacggagcgt gggcgacgcc
    25801 ttgcggagcg acgggacgcc agcgatggac ctgttaggta actcttcagt cttcaaatct
    25861 tgcgcatgct cagtgggctt ttggggataa ctctacctca ttccaaaacg cttctgtata
    25921 cttcaagcta gataaatcgg ttgccgtggg agttgcgcct ccggacacct caagcacctc
    25981 gtttcgaact cgttgctgaa gttgtgggtc ttttgcgaga atcaacagca tgatcgagaa
    26041 caccgctagc gatgtgttcg tcgccgctga tacgatgtga aacgcggtgt tgcccatgtc
    26101 tgttaccgtg aacatgtcat catttttctc acgctgttcc ctcaacatct ttgccaacac
    26161 gctctcccat gcgatcgact tgccctcatc taaagccgcg cgctgttccc tggcagcgct
    26221 cagaaactgg gtacccgtgt tgagaactgc ctctctgaca gctcgagctc tttctttcca
    26281 ctcggccatt ccgaagaact cgggaaggta gcgtagaaac gggaacaagt cccctgcgtt
    26341 cggtgcgacc agggtagcgt actcgtcact gcaatgtctg aactgtttga tttcaaagcc
    26401 atgatcgccc atggaatccg ggcgcctgcc acacactcct aggcatggca cgctcatcat
    26461 ccagcatacg agaatggctt ccagatcctt gccactcgcg gtcggggcct caagcaactt
    26521 gaccaggagt ctggctgtct cggcctcgta gatagggcgg agcctcgtga tggcagccgg
    26581 gccgaaattt ttgttgaagt ccctgcgcca agaggtgagc cagggcgagc tgttctgaaa
    26641 gatggcggct ttgaggtcat ctttgaagat ccatgtgttg ttcatgaact gccaaggacg
    26701 gtcgctgtag actgccccgc gcttttcaaa aagttcacgg actagacggc tgctgttcaa
    26761 tacgacgaca ttggttgcgc ccttcttgac tcccaaggga gtgtcgcttc cataatcttt
    26821 ggcccatttg ccataggtga gaaaagggaa aattctatcg acctggagga ggttgccgag
    26881 gccaggaagc ccgcgcggcc caggagggaa ggctttcgga cgtagagtgt tgaggatgaa
    26941 gatcaaggca tggccgacaa ggatcagcaa gggaaagtag atgaaagagg caggggaaat
    27001 aatgatttct gcaaaccccg tcatgctacc gtaagaaact actttcagcc gatggcgatg
    27061 ttgatgttga acgaattgga ggcgagtgtt atgcgtcgat gagtttaaaa tcctaacatc
    27121 gaaagacctg taactatgcg tttgtctacc ggggcctttc actgggtgct gggaggaata
    27181 acaatgattg aaactgagca atgcgacggg cgtgatatag catccggaat tccgagttga
    27241 ttggtttgtt attctggagc agggaaacaa gaaccacatg aaatagcgtt gtgttctgct
    27301 cggaagagct gtcggagagt cggtcggacc ttggccccgg acataccgac tcggactcgg
    27361 acgtccaccg ggtaagcacg actttcatgc cggtcatcct ggctggaggc acagtggaaa
    27421 tcaacgcgag atttgcaagc aaattgggag ttcgaaagtc caatagttcg atacttagag
    27481 tctttctagc ccacacgtag acgccaaagc tccaaggtta tactcgactg ttcccacaaa
    27541 gatgactctc attcatatag gtcagttagt agaatctcgg ctaatagatt ttttcttcgc
    27601 ctattatatc tctggctgca gcccatgtcc actaacatac cgagactata gttctcttca
    27661 ggtttaaacc tgaggtaacc caagaacaca gagatgcatt cttgcgtgag gtcaagacgc
    27721 tcaaaaattt gccatctgtg aaagagggtc gcctcattgt cggtagcccc tcgttgacgg
    27781 atcccattgc attgagcaaa aagtttgaat tcgctctcgt gagctaccat gagaacatag
    27841 cagcgttgga ggaatatgag gcgagcgagg aacaccaccg gtatgaagga tgcactagcg
    27901 ctgtctgtaa tatccccatt aaccatctac aaagtgttac atcaacatat atgttccctt
    27961 tcgatgaaga cctctgccgc ttcgatttcg aggtcgaccc cgaagacgag tatatgtgtg
    28021 cttttggtcc cttgtcagtt ctgacaggga ttattccaag caacaaaact cccaggaatg
    28081 ggaaaggcga ataggcggat gacatgttag agagagagga cgtgaagaga acactcgttt
    28141 catactgagc tggtattgca gcgcccttga attcggaaat ccagggttct ttggagagat
    28201 ctggttgacc aacttagagt gattggcggc ctgtcccgct acagcaaaca atacaaacac
    28261 ccgctctttt tcgtgtgccc gcaactgtaa tcgcgttcct ttttatcagc ctattgaggt
    28321 cc
//
