LOCUS       BGC0002194             15466 bp    DNA     linear   CON 01-MAY-2017
DEFINITION  Epicoccum nigrum strain ICMP 19927 unplaced genomic scaffold
            scaffold_9, whole genome shotgun sequence.
ACCESSION   BGC0002194
VERSION     BGC0002194
KEYWORDS    .
SOURCE      Epicoccum nigrum
  ORGANISM  Epicoccum nigrum
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae;
            Didymellaceae; Epicoccum.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:07:17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15466
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15466
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[147:8033]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      148..8033
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..15466
                     /SMILES="C(C)CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..15466
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002194"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..15466
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(148..8033)
                     /locus_tag="B5807_07929"
     mRNA            complement(join(148..999,1048..7308,7355..7623,7676..8033))
                     /locus_tag="B5807_07929"
                     /product="hypothetical protein"
     CDS             complement(join(148..999,1048..7308,7355..7623,7676..8033))
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (16-441). E-value:
                     2.9e-181. Score: 594.8. Matches aSDomain:
                     nrpspksdomains_B5807_07929_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (587-893). E-value: 2.1e-99.
                     Score: 324.5. Matches aSDomain:
                     nrpspksdomains_B5807_07929_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (963-1151). E-value: 1e-24.
                     Score: 79.6. Matches aSDomain:
                     nrpspksdomains_B5807_07929_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1456-1648). E-value: 3.1e-77.
                     Score: 251.4. Matches aSDomain:
                     nrpspksdomains_B5807_07929_cMT.1"
                     /NRPS_PKS="Domain: PKS_ER (1867-2180). E-value: 1.9e-117.
                     Score: 383.7. Matches aSDomain:
                     nrpspksdomains_B5807_07929_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2203-2380). E-value: 4.5e-55.
                     Score: 178.3. Matches aSDomain:
                     nrpspksdomains_B5807_07929_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2488-2570). E-value: 9.6e-11.
                     Score: 33.8. Matches aSDomain:
                     nrpspksdomains_B5807_07929_PKS_PP.1"
                     /codon_start=1
                     /db_xref="PFAM:PF00109"
                     /db_xref="PFAM:PF00698"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 250.5; E-value:
                     5e-76)"
                     /gene_kind="biosynthetic"
                     /locus_tag="B5807_07929"
                     /note="EggNog:ENOG410PJA1"
                     /product="hypothetical protein"
                     /protein_id="OSS48297.1"
                     /sec_met_domain="itr_KS (E-value: 6.6e-187, bitscore:
                     609.5, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.5e-100, bitscore:
                     324.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 1.4e-08, bitscore: 22.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.3e-17, bitscore:
                     50.0, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 5e-48, bitscore:
                     151.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.1e-09, bitscore:
                     26.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSNNMDILADEPVMPIAIVGIAGRFPGDASNPSRLWDLIAERRS
                     AMSEIPKDRFTVDTYYHPNNARSNSINTRGAHFMQHQDISSFDAPFFSMTPSEAKATDP
                     QHRMALECTYEALENAGLRLQDLRGTDASCYVGSFTRDYAELAGYDPENIPLHHGTGSG
                     DAMLSNRLSWFFDLRGPSVTIDTACSSSMVALHLGCQSLRTGESKLSIVGGTNLMILPY
                     IMSAMSKLHFLSPDGRSHSFDSRANGYSRGEGVSFVVLKPLDLALRDGDMIRAVIRNTG
                     SNQDGNTPGITVPSAQSQKDLIELCYRNAGLNPADTQYVEAHGTGTQAGDPLEASALAQ
                     TFGASRPPGQPVYIGSIKSNIGHLEGASGLASLTKSVMALEKGLIPPNIWFDKANPRIP
                     MKEWNLQVPTELQPWPTQGQRRVSVNSFGYGGSNVHIIIDDAYHYLKERGLKGRHQTVG
                     DWSSPASEDSGLDSDTALGRSPQLDSIEWSDTDIQAEQVFVWSSSEKAGLQRLATTYQR
                     YLKSSKQNLADRAEARFLRQLSYTLFSRRTAHPWRSFAVASSVKQLLDTLEYSGQMEFA
                     RSSDATPVIVFVFTGQGAQWFAMGRELMSNAIYRATINEAEDYLKSVGCEWSLLEELER
                     DHQTSLLKQPHISQFACTALQVALVNLLREWGVAPQAVVGHSSGEISAAYAAGYVTSET
                     AYCIAYHRGRLSSQLKDKSQTPGAMLATSIDPTEVESYLARIATGKATVACINSPGSIT
                     LSGDLNAIMELEKLLSADGYFARRLQVDAAYHSHHMQAIADEYRECLKDIVPFAEAVPV
                     EMYSSLTGELVDTAGLGADYWVANLTSMVNFNGAVQALTKSLNRAIPVFVEIGPHAALQ
                     GPLKQINKKLNIKFKYTSALLRGSDAVLTTLNMAGNLFLSGVAVDLNRVNAVDENKVKF
                     LADIDPYPWNHSNKYWNESQLVKNQRLRKHPRLDLLGAQTPDLLTQQARFRNILRLHEM
                     PWMEAHQVQGSVLYPAAGMIIMAIEGVKQLADESREIDGYELRDVTIGKAIVVDRSEDG
                     TETMLCIQPRRLGTRADTAAFEEFVIYSLNGETWNQHCSGLVRIRYKSDPNDLFPDESK
                     ITNEAYRKQYQRVLSQCVNSRNMRTYYENLESIGLQYGPLFQNLTEIHKGEFQAVCSLT
                     IPDTKSAMPGKFEYSHVIHPATLDCIVQMGIPAATPLAVDLSAARVPTFAKSLFISADV
                     PSAPGSVLRGYSVASTGESSVDVVVSIDGWEKPLVILEGFKSTTLRSFDSDKSSLRELV
                     STLEWNQDYTMLDPADVKQICSKPIAMLPKNDPFQAGELERLSFIFMKRVLGKFTDEEI
                     RAFPPHISKFYAYMHRVYDRVQKGELQKALRLPSDVDWIKADTASDDELIARVGSESAD
                     GILVCQHGKHLPGIMRGDEDTLQVLLEGDAWTKWYIDGLGCAEINKKLGEYIKLLAHKK
                     PDLKILEIGAGTGGTTLRVLESLGGEVHEDLPHRFRRYDFTDISAGFFEKAAAKFSRFA
                     GRMTFAKLDISEDPLAQGFKEGEYDVVIAANVLHATQNLGTTLQNVRRLMKPSGKLVLN
                     EITIPRLRAFMSVGSLPGWWLGEADGREWAPTIGVEDWDQRLRNAGFTGVDISMADLED
                     PEDQMGSVMVSTAKGNASLMPSDIVLVVHEDPAIQKFATMLSERLSQSAESVTSLSLLE
                     ATEQDLSNRAVIFLLDYDSEHQNLANTDPIRWRLIQKTVLSAEYSMWISRGATIDATNP
                     FASLMSGLSRSMRSENPALRFLLVDLDANEDMASTSNVAGVEKILATASKSTTDARPEN
                     EFAIRGGQICVPRLQLHKGMNDLVRTFNGVSQPQPGPLHQEGRPLNMGVAIPGRLDTLR
                     FATDSAYKAVLAHDDVEIEVKSIGLNFKDLMISMGQLDEPELGFECSGVVRRVGPTVTD
                     TKPGDRVMTFRVGCFRNFVNTPSIMAIPVPDHVDFQTAASVPLVFGTAYYALYEKARLD
                     IGQTVLIHSAAGGVGQAAIMLAQRVGAEIYATVSSAAKKKLLVEKYNIQEDHIFNSRDT
                     SFSKGIMRMTKDRGVDVVLNSLNADFMRESWYCTARFGQFVELGQKDIVGNTGLEMAPM
                     LNNITHHSVNLIAILEHDTATMSRILNTVMQMFGKNMIQAVSPVVGLPIDRVEEAFRTM
                     QTGQHMGKLVLNMEPDSIVSVIPAMSSPAKFKKDATYVLIGGFGGVGRSIAQWMISHGA
                     RNLAFLSRSGASKPEAKKALERFIKQGVKVAVYPCDIANFAEVQSAIESAANEMPPIKG
                     LIQGAMVLEDVPYEHMTYKQFMASVRPKVQGTWNLHNLLGDGLDFFVMLSSSASIVGSR
                     AQGNYAAGNAFQDALALYRTSRGQHASAIDLGIILGVGFLEENTSSNVTANIRTWNFTG
                     IKEQEMQLILSSAITGSSMPGQPALAPHMITGLPTAAMINAQGLKFPSWSNDAKFTHLR
                     DVDPDNAKASVDEDGAQVQSLLRAAKSLDEAIDVVSNAIVNKLAKSMMVDVQDIEKTQT
                     ITKYGVDSLLAVELRSWIYTELQVDISIFELLKTVPILDLAAQIASKSKLLPAGLA"
     aSDomain        complement(178..423)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5807_07929_PKS_PP.1"
                     /evalue="9.60E-11"
                     /label="B5807_07929_PKS_PP.1"
                     /locus_tag="B5807_07929"
                     /protein_end="2570"
                     /protein_start="2488"
                     /score="33.8"
                     /tool="antismash"
                     /translation="AKSLDEAIDVVSNAIVNKLAKSMMVDVQDIEKTQTITKYGVDSLL
                     AVELRSWIYTELQVDISIFELLKTVPILDLAAQIASK"
     aSModule        complement(178..7985)
                     /complete
                     /domains="nrpspksdomains_B5807_07929_PKS_KS.1"
                     /domains="nrpspksdomains_B5807_07929_PKS_AT.1"
                     /domains="nrpspksdomains_B5807_07929_PKS_DH.1"
                     /domains="nrpspksdomains_B5807_07929_cMT.1"
                     /domains="nrpspksdomains_B5807_07929_PKS_ER.1"
                     /domains="nrpspksdomains_B5807_07929_PKS_KR.1"
                     /domains="nrpspksdomains_B5807_07929_PKS_PP.1"
                     /iterative
                     /locus_tags="B5807_07929"
                     /monomer_pairings="mal -> Me-redmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(join(748..999,1048..1326))
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5807_07929_PKS_KR.1"
                     /evalue="4.50E-55"
                     /label="B5807_07929_PKS_KR.1"
                     /locus_tag="B5807_07929"
                     /protein_end="2380"
                     /protein_start="2203"
                     /score="178.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="ATYVLIGGFGGVGRSIAQWMISHGARNLAFLSRSGASKPEAKKAL
                     ERFIKQGVKVAVYPCDIANFAEVQSAIESAANEMPPIKGLIQGAMVLEDVPYEHMTYKQ
                     FMASVRPKVQGTWNLHNLLGDGLDFFVMLSSSASIVGSRAQGNYAAGNAFQDALALYRT
                     SRGQHASAIDLGII"
     CDS_motif       complement(793..900)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0018"
                     /evalue="5.50E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="B5807_07929"
                     /protein_end="2365"
                     /protein_start="2329"
                     /score="60.7"
                     /tool="antismash"
                     /translation="LDFFVMLSSSASIVGSRAQGNYAAGNAFQDALALYR"
     CDS_motif       complement(919..948)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0017"
                     /evalue="6.00E-04"
                     /label="PKSI-KR_m3"
                     /locus_tag="B5807_07929"
                     /protein_end="2323"
                     /protein_start="2313"
                     /score="13.1"
                     /tool="antismash"
                     /translation="PKVQGTWNLH"
     CDS_motif       complement(1225..1323)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0016"
                     /evalue="7.70E-17"
                     /label="PKSI-KR_m1"
                     /locus_tag="B5807_07929"
                     /protein_end="2237"
                     /protein_start="2204"
                     /score="53.8"
                     /tool="antismash"
                     /translation="TYVLIGGFGGVGRSIAQWMISHGARNLAFLSRS"
     CDS_motif       complement(1396..1443)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0015"
                     /evalue="1.70E-06"
                     /label="PKSI-ER_m9"
                     /locus_tag="B5807_07929"
                     /protein_end="2180"
                     /protein_start="2164"
                     /score="20.8"
                     /tool="antismash"
                     /translation="AFRTMQTGQHMGKLVL"
     aSDomain        complement(1396..2334)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5807_07929_PKS_ER.1"
                     /evalue="1.90E-117"
                     /label="B5807_07929_PKS_ER.1"
                     /locus_tag="B5807_07929"
                     /protein_end="2180"
                     /protein_start="1867"
                     /score="383.7"
                     /tool="antismash"
                     /translation="GRLDTLRFATDSAYKAVLAHDDVEIEVKSIGLNFKDLMISMGQLD
                     EPELGFECSGVVRRVGPTVTDTKPGDRVMTFRVGCFRNFVNTPSIMAIPVPDHVDFQTA
                     ASVPLVFGTAYYALYEKARLDIGQTVLIHSAAGGVGQAAIMLAQRVGAEIYATVSSAAK
                     KKLLVEKYNIQEDHIFNSRDTSFSKGIMRMTKDRGVDVVLNSLNADFMRESWYCTARFG
                     QFVELGQKDIVGNTGLEMAPMLNNITHHSVNLIAILEHDTATMSRILNTVMQMFGKNMI
                     QAVSPVVGLPIDRVEEAFRTMQTGQHMGKLVL"
     CDS_motif       complement(1717..1755)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0014"
                     /evalue="2.00E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="B5807_07929"
                     /protein_end="2073"
                     /protein_start="2060"
                     /score="13.9"
                     /tool="antismash"
                     /translation="TKDRGVDVVLNSL"
     CDS_motif       complement(1834..1884)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0013"
                     /evalue="2.50E-06"
                     /label="PKSI-ER_m6"
                     /locus_tag="B5807_07929"
                     /protein_end="2034"
                     /protein_start="2017"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GAEIYATVSSAAKKKLL"
     CDS_motif       complement(1894..1956)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0012"
                     /evalue="1.10E-10"
                     /label="PKSI-ER_m5"
                     /locus_tag="B5807_07929"
                     /protein_end="2014"
                     /protein_start="1993"
                     /score="33.7"
                     /tool="antismash"
                     /translation="GQTVLIHSAAGGVGQAAIMLA"
     CDS_motif       complement(1981..2025)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0011"
                     /evalue="7.70E-05"
                     /label="PKSI-ER_m4"
                     /locus_tag="B5807_07929"
                     /protein_end="1985"
                     /protein_start="1970"
                     /score="16.0"
                     /tool="antismash"
                     /translation="AASVPLVFGTAYYAL"
     CDS_motif       complement(2152..2190)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0010"
                     /evalue="1.00E-04"
                     /label="PKSI-ER_m2"
                     /locus_tag="B5807_07929"
                     /protein_end="1928"
                     /protein_start="1915"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LGFECSGVVRRVG"
     CDS_motif       complement(2209..2244)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0009"
                     /evalue="1.00E-03"
                     /label="PKSI-ER_m1"
                     /locus_tag="B5807_07929"
                     /protein_end="1909"
                     /protein_start="1897"
                     /score="12.1"
                     /tool="antismash"
                     /translation="GLNFKDLMISMG"
     aSDomain        complement(2992..3567)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5807_07929_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="3.10E-77"
                     /label="B5807_07929_cMT.1"
                     /locus_tag="B5807_07929"
                     /protein_end="1648"
                     /protein_start="1456"
                     /score="251.4"
                     /tool="antismash"
                     /translation="LAHKKPDLKILEIGAGTGGTTLRVLESLGGEVHEDLPHRFRRYDF
                     TDISAGFFEKAAAKFSRFAGRMTFAKLDISEDPLAQGFKEGEYDVVIAANVLHATQNLG
                     TTLQNVRRLMKPSGKLVLNEITIPRLRAFMSVGSLPGWWLGEADGREWAPTIGVEDWDQ
                     RLRNAGFTGVDISMADLEDPEDQMGSVMV"
     CDS_motif       complement(4186..4215)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0008"
                     /evalue="4.30E+01"
                     /label="PKSI-ER_m7"
                     /locus_tag="B5807_07929"
                     /protein_end="1250"
                     /protein_start="1240"
                     /score="-2.0"
                     /tool="antismash"
                     /translation="TGESSVDVVV"
     aSDomain        complement(4483..5046)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5807_07929_PKS_DH.1"
                     /evalue="1.00E-24"
                     /label="B5807_07929_PKS_DH.1"
                     /locus_tag="B5807_07929"
                     /protein_end="1151"
                     /protein_start="963"
                     /score="79.6"
                     /tool="antismash"
                     /translation="DLLGAQTPDLLTQQARFRNILRLHEMPWMEAHQVQGSVLYPAAGM
                     IIMAIEGVKQLADESREIDGYELRDVTIGKAIVVDRSEDGTETMLCIQPRRLGTRADTA
                     AFEEFVIYSLNGETWNQHCSGLVRIRYKSDPNDLFPDESKITNEAYRKQYQRVLSQCVN
                     SRNMRTYYENLESIGLQYGPLFQNL"
     CDS_motif       complement(4891..4953)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0007"
                     /evalue="3.40E-07"
                     /label="PKSI-DH_m2"
                     /locus_tag="B5807_07929"
                     /protein_end="1015"
                     /protein_start="994"
                     /score="22.8"
                     /tool="antismash"
                     /translation="HQVQGSVLYPAAGMIIMAIEG"
     aSDomain        complement(5257..6174)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5807_07929_PKS_AT.1"
                     /evalue="2.10E-99"
                     /label="B5807_07929_PKS_AT.1"
                     /locus_tag="B5807_07929"
                     /protein_end="893"
                     /protein_start="587"
                     /score="324.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFTGQGAQWFAMGRELMSNAIYRATINEAEDYLKSVGCEWSLLEE
                     LERDHQTSLLKQPHISQFACTALQVALVNLLREWGVAPQAVVGHSSGEISAAYAAGYVT
                     SETAYCIAYHRGRLSSQLKDKSQTPGAMLATSIDPTEVESYLARIATGKATVACINSPG
                     SITLSGDLNAIMELEKLLSADGYFARRLQVDAAYHSHHMQAIADEYRECLKDIVPFAEA
                     VPVEMYSSLTGELVDTAGLGADYWVANLTSMVNFNGAVQALTKSLNRAIPVFVEIGPHA
                     ALQGPLKQINKKLNIKFKYTSALLR"
     CDS_motif       complement(5821..5937)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0006"
                     /evalue="6.40E-12"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="B5807_07929"
                     /protein_end="705"
                     /protein_start="666"
                     /score="37.5"
                     /tool="antismash"
                     /translation="GVAPQAVVGHSSGEISAAYAAGYVTSETAYCIAYHRGRL"
     CDS_motif       complement(6124..6180)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0005"
                     /evalue="1.10E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="B5807_07929"
                     /protein_end="604"
                     /protein_start="585"
                     /score="20.9"
                     /tool="antismash"
                     /translation="VFVFTGQGAQWFAMGRELM"
     aSDomain        complement(join(6613..7308,7355..7623,7676..7985))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B5807_07929_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.90E-181"
                     /label="B5807_07929_PKS_KS.1"
                     /locus_tag="B5807_07929"
                     /protein_end="441"
                     /protein_start="16"
                     /score="594.8"
                     /tool="antismash"
                     /translation="IAIVGIAGRFPGDASNPSRLWDLIAERRSAMSEIPKDRFTVDTYY
                     HPNNARSNSINTRGAHFMQHQDISSFDAPFFSMTPSEAKATDPQHRMALECTYEALENA
                     GLRLQDLRGTDASCYVGSFTRDYAELAGYDPENIPLHHGTGSGDAMLSNRLSWFFDLRG
                     PSVTIDTACSSSMVALHLGCQSLRTGESKLSIVGGTNLMILPYIMSAMSKLHFLSPDGR
                     SHSFDSRANGYSRGEGVSFVVLKPLDLALRDGDMIRAVIRNTGSNQDGNTPGITVPSAQ
                     SQKDLIELCYRNAGLNPADTQYVEAHGTGTQAGDPLEASALAQTFGASRPPGQPVYIGS
                     IKSNIGHLEGASGLASLTKSVMALEKGLIPPNIWFDKANPRIPMKEWNLQVPTELQPWP
                     TQGQRRVSVNSFGYGGSNVHIIIDDA"
     CDS_motif       complement(6829..6873)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0004"
                     /evalue="1.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="B5807_07929"
                     /protein_end="369"
                     /protein_start="354"
                     /score="11.0"
                     /tool="antismash"
                     /translation="GSIKSNIGHLEGASG"
     CDS_motif       complement(6934..6981)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0003"
                     /evalue="2.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="B5807_07929"
                     /protein_end="334"
                     /protein_start="318"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YVEAHGTGTQAGDPLE"
     CDS_motif       complement(7174..7212)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0002"
                     /evalue="2.80E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="B5807_07929"
                     /protein_end="254"
                     /protein_start="241"
                     /score="11.0"
                     /tool="antismash"
                     /translation="FDSRANGYSRGEG"
     CDS_motif       complement(7400..7447)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B5807_07929_0001"
                     /evalue="1.30E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="B5807_07929"
                     /protein_end="194"
                     /protein_start="178"
                     /score="20.3"
                     /tool="antismash"
                     /translation="GPSVTIDTACSSSMVA"
     gene            complement(8421..10137)
                     /locus_tag="B5807_07930"
     mRNA            complement(join(8421..9617,9675..10003,10074..10137))
                     /locus_tag="B5807_07930"
                     /product="hypothetical protein"
     CDS             complement(join(8421..9617,9675..10003,10074..10137))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 90.2;
                     E-value: 2.7e-27)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="B5807_07930"
                     /note="CAZy:GT1; EggNog:ENOG410PFEC"
                     /product="hypothetical protein"
                     /protein_id="OSS48491.1"
                     /transl_table=11
                     /translation="MTEPVQAKILVIITAGGKSNAAPMLEVARILHSRGHTIELATLAG
                     NEGWAAECSFVTRTYKLGPGVPEDVEEREYLAMSTWENSRYTTDYSAMFRSRRFMAHSW
                     PNVYKSLCIIVEDEKTRPDLLLADYGVDAARDMTIQYGLPIALHYSQMPTSMLYASYIP
                     GIPGLQFEILTSENASLAQRLLNDLLPLRLLGSFIRHGTWLREMRAAAGVRWALPRAKK
                     PDHLILVNSFFGLEVPKDLPPLVAPVGPILGETFPQLGPELGAFIEARHRILYVSLGTH
                     VLLSHDALYKILTGAAKALQENLFDGVLWSMRGLAKKQFDLKADLPPELGLSKATVGDL
                     FESAHPNFVLVAFAPQRAILEHAHTVAFLSHCGPASANEAAYHGVPIIGIGVYFDQLQC
                     ALRLRDAGVAVILDKTLFSPDDIREALRQVSTDENGTFKANCRRLQRIARIASKRKFHA
                     ADLIEEVLIHADAKAELGQLGPPLHLQTADTRLPRWKANAWDIKLIKLVSVACVCGVLR
                     LAYCGILGAGSN"
     gene            complement(11171..12950)
                     /locus_tag="B5807_07931"
     mRNA            complement(join(11171..11417,11478..12025,12070..12284,
                     12330..12733,12778..12950))
                     /locus_tag="B5807_07931"
                     /product="hypothetical protein"
     CDS             complement(join(11171..11417,11478..12025,12070..12284,
                     12330..12733,12778..12950))
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR017972"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 273; E-value: 8.4e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="B5807_07931"
                     /note="EggNog:ENOG410PW4T; GO_function: GO:0005506 - iron
                     ion binding [Evidence IEA]; GO_function: GO:0020037 - heme
                     binding [Evidence IEA]; GO_function: GO:0016705 -
                     oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen [Evidence
                     IEA]; GO_process: GO:0055114 - oxidation-reduction process
                     [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="OSS48490.1"
                     /sec_met_domain="p450 (E-value: 6.5e-52, bitscore: 164.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFASELPRKIMGVTPVHVCIFGVSFFIVYLVSLTFYRLYLHPLR
                     KFPGPKLAAVTFWYEFYFDCVQRGQYVFKIEELHRRYGNVVRINPSELHFADPEFFNDI
                     YCNAQKKRDKWDWMVNGLFINKSLFGTVSHDLHRERRAALNNLFSKAQVRKQQKDVQRC
                     VDIMLERMRVAGQNREVIDLKVAFAAFTADVAMGFAYGRGDNKLSAPDFDPDFGRAVEK
                     GLNSLALMNHLPWLGYSVLLARYAPERIIQKLRMTSFMELQRSIARQARQVLLDQEITA
                     KSRPTVFQQIMASKLPDSEKTLPHLVQNGGLIVSAGTVSTAWALCVGVFYVLHQPTVLQ
                     KLQAELLEAIPDRSADIDIVQLEKLPYLAAVIQEALRLSVGGTHRSQRIAPNEITVYPD
                     RDTGKTWSVPAGTPMSMSHLLLFRNERIFPDHERFDPERWLGKPGMDRYQFAFSKGTRN
                     CIGINLAMAEMMLMLAGIFRSCQNSNGLKFQDYLTHIELFDTSVRDVETVGDGGVPFQH
                     PESKGVRVMLS"
     gene            13478..15389
                     /locus_tag="B5807_07932"
     mRNA            join(13478..13551,13597..13854,13899..14105,14149..14490,
                     14537..15389)
                     /locus_tag="B5807_07932"
                     /product="hypothetical protein"
     CDS             join(13478..13551,13597..13854,13899..14105,14149..14490,
                     14537..15389)
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 305.6; E-value:
                     7.7e-93)"
                     /gene_kind="transport"
                     /locus_tag="B5807_07932"
                     /note="EggNog:ENOG410PH0T; GO_component: GO:0016021 -
                     integral component of membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="OSS48493.1"
                     /transl_table=11
                     /translation="MSNDTRPIAKLATLSGHRLWINVAILCVGLFLSALETTIIATALV
                     SIGNSLGDYSKASWVVTSYLLSYTGFLTIFARCSDVFGRKTILLIGLVTFTAASCACGA
                     ATSMIQLIIFRAFQGLGGAGIYSLAMRAITEIPSQKTMGPVAGLIGVVFACSSIAGPLL
                     GGAIVSSSSWRWVFYLNAPAGGVLILLVIFIFPANATPLQLSYKDLQRVDWTGGWLSLA
                     AITLLIFALQSGGSEYEWNSAPVVSTLVGAGTCLVLFLLYEAFLGRGSKDDQTLPIYPT
                     RLLKNWRLNAALLTSLIIGFPFMITIIQLPQSFQIVASRSAVRAGIDMIPLLIFSALGS
                     GLGGALCSRKPIERELLAISFMLQLIGLGPLYSVRLTGAALASHYVYESLAGLGFGLSL
                     SSITIVARRSVDEDDLSVAMGLTTQLRVLGGLIGIGAAQSLLNRVTGRDLKSYVSAEVR
                     ARLQSSVENIHTLSKEQQDTVRRFYGRGYRQQIIVSLSTAALGLVLALAMTATRGATVE
                     KDTPDETPSEDSELRRLPPLETYQIDQVGHVSDPSDVGSLTTAPTIRNPKNSPQELLES
                     V"
ORIGIN
        1 gatcaggacc tgtaggaccg acttgcaccg caacataata tgttccaaca tgaacttgtt
       61 tatcaataag caagggtcta agatatatac cagtgactat tacgccttga atccttcata
      121 tctgtgtagt catttgctca atgccctcta agccagtcca gctggcaaaa gcttactttt
      181 acttgcgatc tgtgctgcca agtctaagat tggcacagtc ttcaacaact cgaaaatcga
      241 gatatcgacc tgcaactctg tgtaaatcca gctcctcaac tccacagcaa gtagactgtc
      301 aacgccgtat ttggtgattg tctgggtctt ctcgatatcc tgaacatcga ccatcatgct
      361 tttggcgagt ttgttgacga tggcgttcga gactacgtcg atagcctcat cgagagattt
      421 agctgcacga agcaagcttt gaacctgtgc cccatcttcg tcaacgcttg cctttgcgtt
      481 gtctggatcg acatcgcgta agtgggtgaa ctttgcgtcg ttactccatg acgggaattt
      541 gaggccctga gcattgatca tcgcggcggt aggcaatcct gtgatcatgt gcggtgcaag
      601 tgctggctga cctggcatac tagaaccggt gatagcagaa ctgaggatca gctgcatctc
      661 ttgctccttg atacccgtga agttccaggt gcggatattg gctgttacgt tcgagctcgt
      721 gttctcttca aggaaaccaa cccccagaat gataccgaga tctatggcag aagcgtgctg
      781 tccacgagac gtcctatata aggccagggc gtcttggaac gcattgccag cagcgtaatt
      841 gccttgggcg cgggaaccga caatgctggc agaggaagag agcatgacaa agaagtcgag
      901 cccgtcgcca agcaaattgt gaaggttcca cgttccctgt acctttggac gtactgaagc
      961 catgaactgc ttataagtca tgtgttcata tggcacatcc tgcacgagtt agttttatat
     1021 acaccagggt atcgtactgg aacatacctc caacaccatc gcgccttgaa tgagtccctt
     1081 gatcggaggc atctcgtttg ctgcggactc gatggcagat tgcacctcgg caaaattggc
     1141 aatgtcgcag ggatacacgg caaccttgac accctgtttg atgaatcgct caagtgcctt
     1201 cttggcttca ggcttcgatg caccggacct tgagaggaac gccagatttc gagctccatg
     1261 gctaatcatc cactgcgcga tcgagcggcc gactccacca aagccaccta taagcacata
     1321 cgtagcgtcc ttcttaaact tggctgggct tgacattgct ggaatgacgg aaacaatact
     1381 gtcaggctcc atattcagga caagtttacc catgtgctga ccagtctgca ttgtacggaa
     1441 agcctcttcc acgcgatcga tcggtagtcc gacgactgga cttactgcct ggatcatatt
     1501 tttgccgaac atctgcatca ctgtgttgag gatgcgtgac attgttgcgg tgtcatgctc
     1561 caggatggca atcaggttga cggagtgatg cgtgatattg ttgagcatag gtgccatctc
     1621 taggccggta ttaccgacaa tgtccttctg accaagttca acgaactggc cgaagcgggc
     1681 agtacaatac caagactctc gcatgaaatc tgcgttcagc gagttgagga ctacgtcaac
     1741 acctcggtcc tttgtcatgc gcatgatgcc cttcgagaag gaggtgtcac gactgttgaa
     1801 gatgtgatcc tcttgaatgt tgtacttctc tacaaggagc ttctttttcg cagcagatga
     1861 gacagtagca tagatctctg cgccgacgcg ctgggcaagc ataatggccg cttgacccac
     1921 acctccagcg gcagagtgga tcaagacagt ctggccgatg tcaagccgtg ctttctcgta
     1981 cagagcatag tacgctgttc cgaataccaa cggcacagaa gccgcggttt gaaaatcgac
     2041 gtgatcgggg actggaatgg ccatgatcga tggtgtgttg acaaagttgc ggaaacatcc
     2101 aactctgaac gtcatgactc ggtctccagg cttggtgtca gtcacggtag ggccgacacg
     2161 gcgtacgaca ccgctgcatt cgaaacccag ctctggctca tcgagctgac ccattgagat
     2221 catgagatct ttgaagttca gtccgatgct cttgacttcg atctcaacgt catcatgggc
     2281 gagcacagcc ttgtatgcgc tgtcggtcgc gaatcgaagc gtatcaaggc gaccaggaat
     2341 cgcgacgccc atgttcaaag gacgtccttc ctgatggagc gggccaggct gaggctgaga
     2401 tacgccgttg aatgtacgta ctaagtcatt catgcccttg tgcagctgga gccttggaac
     2461 gcaaatctgc cctcctctga tggcaaattc attctcaggt cgcgcatcag tcgtagattt
     2521 gcttgctgtc gcgagaatct tctctacacc agctacattt gacgtactgg ccatgtcctc
     2581 attggcgtcg agatcgacga gcaggaatcg aagagccggg ttctcactac gcatcgaacg
     2641 ggacagtcca ctcataagac ttgcaaacgg attcgtggca tcgattgtcg cgcctcgcga
     2701 gatccacatt gaatattctg cgctcaaaac ggttttctga atgagcctcc accttatagg
     2761 atcggtgttg gcaaggtttt gatgctccga gtcgtagtcg agtaggaaga tgactgctcg
     2821 gttcgacaaa tcttgctcgg tagcttccaa cagggaaagg gaagtgacac tctctgctga
     2881 ttgcgaaaga cgctccgaga gcatggtcgc aaacttctgg atcgcgggat cttcgtgtac
     2941 gaccaatacg atatcggatg gcataagcga agcgttgcct ttcgcggttg agaccattac
     3001 agaccccatc tgatcttctg gatcttcaag gtcggccatg cttatgtcta caccagtgaa
     3061 acctgcgttg cgaagcctct gatcccaatc ctcgacgcca atggtaggag cccattctcg
     3121 accatcagcc tcgcctaacc accaacctgg gagggagcca acactcatga atgcgcggag
     3181 acggggaata gtgatctcat tgagcactag tttcccacta ggcttcatca accttcgcac
     3241 attctgcagt gtcgtcccga gattctgggt tgcgtgcaag acattggctg caataaccac
     3301 atcgtattca ccttctttaa agccctgtgc gaggggatcc tctgagatat ccagcttggc
     3361 gaaggtcatt cttcctgcaa atctgctgaa tttggcggcg gctttttcga agaagccggc
     3421 gctgatgtcg gtaaagtcgt agcgcctgaa gcggtgtggc agatcctcgt gcacttcgcc
     3481 gcccaagctc tccaacacgc gaagggtagt gcctccggtg ccagcgccaa tttcgaggat
     3541 cttcaagtcc ggcttcttat gcgcgaggag cttgatgtac tcgcccagct ttttgttgat
     3601 ctctgcgcag ccaagtccgt cgatgtacca tttcgtccaa gcatcgcctt caagaagcac
     3661 ctggagcgta tcttcatctc cacgcatgat tccaggaagg tgttttccat gctggcacac
     3721 taggattcca tcagcggatt cggagcccac tcgtgcaatg agctcgtcat cggacgcagt
     3781 gtcggctttg atccagtcaa catcggaagg taagcgaagt gctttctgaa gctctccttt
     3841 ctgaacgcga tcgtacaccc tatgcatgta cgcgtagaat ttgctgatgt gaggggggaa
     3901 tgcgcggatt tcttcgtcgg tgaattttcc cagcactcgc ttcatgaata tgaaggagag
     3961 acgttccagc tctcctgcct ggaaaggatc gttcttaggc agcatggcga taggcttgga
     4021 gcaaatctgc ttgacatcgg caggatcaag catggtgtag tcttggttcc attccagagt
     4081 actgacaagc tcacgcagtg acgatttgtc cgaatcgaaa ctcctcagtg tggtactctt
     4141 gaaaccttcg aggatgacta atggcttctc ccagccgtcg atggacacca ctacatcgac
     4201 agaagattcg cccgtgctcg cgacggaata gccgcgtaga acggatcctg gtgctgacgg
     4261 aacatctgca gagataaaaa ggctcttcgc aaaagtagga actcgcgcag cggataagtc
     4321 aactgctaaa ggcgtggcag ccgggattcc catctggaca atgcagtcca aagtggctgg
     4381 gtgaatgacg tgagagtatt cgaacttacc gggcatggcg ctctttgtat cgggaatggt
     4441 caatgaacag acagcctgga actcaccctt gtgaatttcg gtcaaatttt ggaagagcgg
     4501 accatactgg agaccaatac tctctaggtt ctcatagtac gtgcgcatgt tgcgggaatt
     4561 cacacactgg ctcaagactc tttgatactg cttacggtag gcctcgttcg tgatcttgct
     4621 ctcatctgga aacaagtcgt tggggtcgga cttgtatcgg atgcgcacca gtccagagca
     4681 gtgctggttc catgtttcgc cgttcagaga gtagataacg aattcttcga atgctgcggt
     4741 atctgctcta gttcccaacc tccgaggctg aatgcagagc atcgtttcgg tgccgtcctc
     4801 tgatctgtcg acaactatgg ctttgccgat cgtcacgtcc cgcagttcgt acccatcaat
     4861 ctctcgggac tcatcagcaa gctgtttgac tccttcgatg gccattatga tcatgcctgc
     4921 agcaggatat agtacagatc cttggacctg atgcgcttcc atccatggca tctcgtgtag
     4981 acgaagaatg ttgcggaaac gagcttgctg ggtgagaagg tcgggtgttt gggcaccgag
     5041 caggtccaag cgagggtgtt tcctcaaacg ctgattcttg acgagttgtg attcgttcca
     5101 gtacttgtta gaatggttcc aaggatatgg atcgatgtcg gcgaggaatt tgactttgtt
     5161 ctcgtccacg gcgttgactc ggtttaggtc gacagcaaca ccagatagga agaggttgcc
     5221 cgccatgttc aatgttgtga gtacagcatc cgagcctcga agaagtgccg aagtgtactt
     5281 gaacttgata ttgagcttct tgttgatctg cttcagaggc ccttgaaggg cagcatgcgg
     5341 tccgatctct acaaagactg gaatggcgcg gttgagggat ttggtcagcg cttgcacggc
     5401 tccgttgaag ttgaccatgc ttgtcaagtt ggcaacccag taatctgctc caagaccagc
     5461 agtatctaca agctcaccag tgagactgga gtacatctca actgggacgg cctctgcaaa
     5521 aggaacgatg tccttgagac attcgcgata ctcgtcggca atcgcttgca tatggtgaga
     5581 atggtatgca gcatcaactt gaagacgacg agcgaagtag ccatctgcgg aaagcagctt
     5641 ttccagctcc atgatggcgt tcagatctcc agacagggtg atgctaccag gactgttgat
     5701 gcaagcaaca gtcgccttac ccgtcgcgat acgagcgagg taggactcaa cttcagtggg
     5761 atctatactt gttgccagca tggcaccggg agtctgtgac ttatctttga gttgactgga
     5821 aagtctgccc cggtggtagg caatgcaata agcagtctca ctcgtgacgt atcctgctgc
     5881 atatgctgcc gatatctcgc cacttgaatg accaacaact gcttgtggtg ctacgcccca
     5941 ctcccgcaag agattgacca gggctacctg aagggcagtg cacgcgaatt gactgatgtg
     6001 aggctgtttc agcagggaag tttggtggtc tcgttccagc tcctcaagta atgaccattc
     6061 gcagccaaca gacttgaggt agtcctcggc ctcattgatg gtggctcgat aaatggcgtt
     6121 ggacatgagt tcgcgaccca tggcaaacca ttgcgcaccc tgccccgtga agacgaagac
     6181 aatgacggga gtagcgtcgg aagatcgggc aaattccatc tgtccagaat actcaagggt
     6241 atccaaaagc tgtttgacgg acgatgctac cgcaaaggat ctccagggat gagcggttct
     6301 acgagaaaat agtgtgtagg agagttgacg aaggaagcga gcctcagctc tgtctgccaa
     6361 gttttgcttt gacgatttca aataccgctg atatgttgtt gccaggcgtt gaagaccggc
     6421 tttctcggac gaggaccaca caaacacctg ttcagcttga atgtctgtgt cggaccactc
     6481 aatgctatcc agctgtggtg atcttcccag tgcagtgtct gagtctagcc cagaatcctc
     6541 agatgcgggt gatgaccagt ctccaacagt ctggtggcga ccttttagac cccgttcctt
     6601 taggtaatgg taggcatcgt cgatgatgat gtggacattg ctgccgccat atccgaatga
     6661 gttcacactg acgcgacgtt gaccttgagt gggccatggt tgcagctctg ttggcacttg
     6721 cagattccac tccttcattg ggatacgagg attggccttg tcaaaccata tatttggagg
     6781 aataaggccc ttttcaagtg ccatgacgga ttttgtgagc gaagccaggc cagaggcacc
     6841 ctcaagatga ccgatgttgg acttgattga gccaatgtac actggttgac ctggcgggcg
     6901 cgatgcaccg aatgtttggg ccaacgctga tgcctccaag ggatctccag cctgcgtgcc
     6961 ggtaccatgg gcctcgacat attgagtatc agctgggttc aagccggcgt ttctgtagca
     7021 cagctcgatg agatcctttt gagattgagc agaaggcact gtaataccgg gtgtgttacc
     7081 atcttggttt gagcctgtat ttcggataac agcacggatc atgtccccat ctcggagggc
     7141 tagatcaagc ggtttgagca cgacgaaaga aacaccttct cctcgcgagt atccattggc
     7201 tcgggaatca aatgagtgag atctcccgtc cggactgagg aagtgcagtt tggacatcgc
     7261 tgacatgatg tatggtagga tcatcaggtt cgtaccgcca acgattgact caaaacgtta
     7321 gctggaggtc gaaaaaggga cgagtctaac tcaccagctt ggattcacca gttcgcagac
     7381 tctgacatcc aagatgaagt gccaccatgg atgaagagca cgcagtgtcg atcgtcacgc
     7441 taggaccccg cagatcgaag aaccaagata agcgattgga caacatcgca tctcccgatc
     7501 cagtgccatg gtgcaatgga atgttctcag ggtcatagcc tgcaagctcc gcgtagtcgc
     7561 gtgtaaagct accaacatag caggatgcat cagtcccgcg taaatcttgg agacgaagac
     7621 cagctagtat cccatcagtc caacatgtaa ggaccccaac catcgtgtaa cataccattc
     7681 tcaagtgctt catatgtgca ttctaaagcc atacgatgct gggggtcggt agccttagct
     7741 tcactggggg tcatggagaa gaacggagca tcgaatgacg atatatcctg gtgttgcatg
     7801 aaatgagcac ctcgagtgtt aatcgagttc gagcgtgcgt tgttgggatg atagtaggtg
     7861 tctactgtga acctatcctt tgggatttca ctcattgccg accgtctttc agcaatgagg
     7921 tcccagaggc gcgaagggtt ggatgcatct cctgggaatc gaccagcgat acccacgata
     7981 gcaataggca tcactggttc atctgctagt atatccatgt tgtttgaaga cataagtggt
     8041 tatgacgatg taaggtagat gaatcgtgca ggaactaaca attgaataat cctgttgtgt
     8101 aggaagacgg ttgagcgttt gatctcgatg ggagagatgt tccctgatat ttatgagcgc
     8161 gaaggctcac aaagatgttc agtgagttga atagcctccg ccgttcccaa gaacgccaag
     8221 cgaaaccacc atgccaacac aataaggccc gtaaaaacca cgaagaccaa ccgataagaa
     8281 tacgagagat taaccgtact tccccacgtc tcaaatccaa gacacgctga ccacctctac
     8341 gatttagatg gccgatgcac tggtcgtttg acgcagaacc ctcgcatcca gggtcttaga
     8401 attggaggcc tcacaatcag ctagttggat cctgccccaa ggattccaca ataagccagg
     8461 cgaagcacgc cacaaacgca agcgacgctg acaagcttga tgagcttgat atcccacgca
     8521 ttggccttcc aacgcgggag cctcgtatct gcggtttgaa ggtgaagtgg tggcccaagc
     8581 tgaccaagct cagcttttgc atcagcgtgg atgagtacct cctcgatgag atcggcagcg
     8641 tggaacttgc gcttacttgc gatgcgggcg attcgctgca ggcggcgaca gttggctttg
     8701 aaggtgccat tctcatccgt cgagacttga cgaagagcct ctcggatatc atctggtgaa
     8761 aataatgttt tatcgagtat cacagcaacc ccagcatcac gtagcctcag tgcacactgg
     8821 agctggtcaa agtagacacc aatgccaatg atgggtacac catgataagc ggcctcattg
     8881 gcactagctg gaccacagtg gctgagaaag gctactgtat gagcatgttc tagaatggct
     8941 cgttgaggcg cgaatgcaac tagcacgaag ttgggatgag cgctttcgaa gaggtcgccg
     9001 actgtagcct tagagagacc caattccggt ggtagatctg ccttgaggtc aaactgtttc
     9061 ttggcgaggc ctctcatgga ccagaggact ccatcgaaaa ggttttcttg gagagccttg
     9121 gcagcgccgg tcaggatctt gtacaatgca tcatggctga gcagaacatg cgtgccaaga
     9181 gatacataca gaatcctgtg gcgggcctca atgaaagcac cgagttcggg cccaagctgg
     9241 ggaaaagtct cacccaggat gggtccgact ggtgccacca gaggaggaag atccttcgga
     9301 acttccaagc caaagaagga gttcaccaaa atcaggtgat ctggtttctt ggcgcgaggc
     9361 agagcccatc ttacacctgc agcggctcgc atttcccgca gccaggttcc gtggcgaatg
     9421 aaggacccta gaagacgcag cggcagtaga tcattgagca gccgttgcgc taacgaggca
     9481 ttttcactgg tcaaaatctc aaactgcaag ccggggatcc cgggaatgta acttgcatac
     9541 agcatgcttg tcggcatctg actgtaatgc aaggcaatgg gtaagccgta ttgaatcgtc
     9601 atatctcgtg cggcatcctg tgttggtgac acaagtcagt acgtgctcag cagttggaat
     9661 aggcaatgac ttacaacacc gtagtctgcg agaaggaggt cgggccgggt cttctcatct
     9721 tcaacgatta tgcagagtga tttgtaaaca ttaggccatg agtgggccat gaaccgacgc
     9781 gagcggaaca tggctgaata gtcggttgtg tatctggaat tttcccaggt gctcatggca
     9841 aggtactcac gttcttcaac gtcttcgggt acaccgggac ctagtttgta cgttctggtg
     9901 acgaaactac attctgcggc ccacccctcg tttccagcaa gggtggccag ttcgatggta
     9961 tgaccacgcg aatgtagaat tcgtgcgacc tccaacattg gggctgcagc gccatggtgt
    10021 cagcgtgggg gccttgtgct actccaaatt ggctgagaac aggtcaattt tacctgcatt
    10081 ggactttccg ccagccgtta taatcaccag aatcttcgct tgtacaggtt ccgtcattgt
    10141 tggcgctttg atagggctaa gattcggtgg caattatcaa aattggctag aagtagtctt
    10201 atggagatgg cagtgattgg atgcaagtca atttgcttgc tgttcggtgt aagactggct
    10261 accacccgta tgaaaatgtg tggtttaata gctacaagtt gtggaccgtg cactcgaaca
    10321 tgagtgtact accgctagaa gtgatggtgg aaaactgcgg agagttcctt gcgagctatg
    10381 gggtatcagt atactcatgc tgtaagacat gtcagtctat aatagtcaca agagtgacgt
    10441 acgaaacctg taaggctcac ttgcaccgca atagaatttc ctggggcaac ctccaagtct
    10501 gaccggccga actgtcatgc ctgatcggcg atttaagacc aagaccccac ggccacatat
    10561 gagagctttt cacgccatgt ggtagtatcc tatcaggaag cgtatattct tgactcatct
    10621 ttcatgtatc accatgtgta catgcagcgc tcatcacaca agataatgca gtctcaccac
    10681 cgcttcccat ctgacgggcc gaacgaacga gccgaaacat cgtgctagct acccgcggaa
    10741 agccgtcata ctgcataaat cccttgaacg tctagtgttg agatgtatga agccctgacg
    10801 ggcagtcaag cagccaggac gtgttatcac tgaaggatgc agtggcttat gcagagcggg
    10861 gcggaaaacg tttagcgcat ccatcctcaa ttgatattca caatgagccg caggctcggt
    10921 agagggatct gcagcgcgct agtgagctta tacaggccac ccgctcagcc aagtctgagc
    10981 cacgctcaat gaggtgtgtg ttaatgttgt tcctccaacc tcatctgatt ttcccaggaa
    11041 acaggttaga gctccaagtt tgtatgcatc ttccaaaatt ccgaattcat ctcagacaac
    11101 gatcatctcc aaaaataagt acaattcttg atttccggga tgttgaatcc cggtatctga
    11161 ccaaagtcat ctaggatagc ataacgcgta cacccttaga ttctggatgt tggaacggaa
    11221 ctcccccatc tccgaccgtc tccacatctc gaacacttgt atcgaaaagt tctatgtgag
    11281 tcaggtaatc ttggaacttc aagccgttgc tgttctgaca acttcggaat ataccggcca
    11341 acataagcat catctccgcc atagcaaggt taatgccaat gcagtttcga gtgcctttgc
    11401 taaacgcaaa ttgatacctg cgccatcgta atgttaaaca tcgggtcagg gatgatttgg
    11461 atgatgagaa gacgtaccga tccatgcccg gttttccaag ccaacgctcc ggatcaaatc
    11521 gctcgtggtc tgggaaaatt ctctcatttc ggaacaatag taaatgagac atgctcatgg
    11581 gcgttccggc agggacagac cacgtctttc ccgtatcgcg gtcagggtaa acagtaatct
    11641 cgttaggtgc aatgcgctgt gatcggtgag taccacctac actgagacgc agagcctcct
    11701 gtatgacggc ggcgagatat ggcaatttct cgagctgaac aatgtctatg tcggccgagc
    11761 gatctggtat tgcctctaac agctcggcct gcagcttttg gagcacagta ggctggtgca
    11821 gaacatagaa tactccaaca caaagagccc atgctgtgct gacagtacct gcgctaacga
    11881 tcaaaccgcc attctggact agatgtggaa gtgtcttctc tgaatcaggt agcttgcttg
    11941 ccattatctg ttggaaaact gttggacggg acttcgccgt gatttcctga tctagaagca
    12001 cctgccgggc ttgtctcgca atgctctatg ctcatcagta gtgctatgga tttggagagg
    12061 aagtcttact cgctgaagtt ccatgaatga tgtcatgcgg agcttttgga taattctttc
    12121 aggtgcataa cgcgcaagga ggaccgagta acccagccat ggcagatgat tcataagcgc
    12181 tagagaattc aatcccttct caactgcgcg gccaaaatcg ggatcgaagt cgggggcgct
    12241 tagtttgttg tctcctcgcc cgtacgcaaa ccccattgcg acgtctacat tcatcagcta
    12301 aaataaattt ccatgattac atggcgtacc ggctgtaaag gcggcaaagg caaccttgag
    12361 atcaatgacc tccctgtttt ggcctgctac tctcattctt tccaacatga tatcgacgca
    12421 tctctgaaca tccttttgct gttttcgaac ttgggctttc gagaataggt tgttcagtgc
    12481 tgcccttcgt tctcgatgta gatcatgaga tactgttccg aacagtgact tattgatgaa
    12541 caggccgttg accatccaat cccacttgtc ccgcttcttt tgcgcattgc agtagatgtc
    12601 gttgaagaat tcagggtccg caaagtgcag ctcagacggg ttgatgcgaa cgacgttacc
    12661 gtaccgtctg tggagctcct caatcttgaa tacatactgc cctcgctgga cacagtcaaa
    12721 gtagaattca taccttctga gtcagtagag ctacagaatc ttgaaaggag gtctcaccaa
    12781 aaggttaccg cggccagctt tggccctgga aactttcgca gggggtgcag gtagaggcgg
    12841 tagaatgtga gagacaccag ataaacgatg aaaaatgata ctccaaaaat acatacgtgg
    12901 acgggtgtaa cccccataat ttttcgtggt aattcagaag caaactccat tctgttttgt
    12961 tcgaaaagga tgaacaaagg tggcagaatt gatagatagg tagtttgagt aatccgaccg
    13021 cagcaacctg ttgcacctgg ggctcatcga cgatcacgtt gttggcatca ggaggggtcg
    13081 atccaccgtg gcgtgcgttt ggaaacacct gtaaggcaag actccttagg cctcctgaga
    13141 taatacgctg cttgcagtag acccttgtca gtggcgcaag ggcgggtggg acatccgctg
    13201 tacagatgta agcgcgccaa gaagccataa gctcatccca cttttatggg gcagggtcgg
    13261 tccggagacg gagtaatcct tcatgcacgt cagcacgccc atagtgttgg cgggcaaacg
    13321 tgttcgtctg ccgaggaaga cccgcaagta ctgtcagctg gatttcgctt tcgcttgtgt
    13381 acgggtaccg aatgatgccg agggatcaac ttttgcgtct tcgatatctg cctgttcgct
    13441 atctagacgc ttaattgctt gaacctgatc ttccctcatg tcgaacgata cacgaccgat
    13501 tgcgaagctc gcaaccctgt ctggccatag gctctggatc aatgtcgcga tgtgagtttt
    13561 caagcacact accagatctc agtctcattc gaacagtcta tgtgtcggac tgttcctatc
    13621 tgccctcgag actaccatca tagctacagc tttggtgtct attggaaata gcttgggcga
    13681 ctatagcaag gcgagctggg tggtaacgtc atatttgctc agttacacag gttttctgac
    13741 catttttgct cgctgctctg atgtctttgg tcgcaaaaca attctactca ttggtctcgt
    13801 gacattcaca gcagcatcat gcgcatgcgg tgcggcgacg agcatgatac agttgtatgc
    13861 aatccacccg ctgtagcaag ccagtctgat catgatagga tcatcttccg tgcctttcag
    13921 ggcttaggcg gagccggcat ctacagtctg gctatgcgtg ccattactga aataccaagc
    13981 caaaagacta tggggcctgt agcagggctt atcggtgttg tatttgcctg ctccagtatt
    14041 gcggggccct tattgggagg cgcgattgtc tcatcctcgt cttggagatg ggtgttctac
    14101 ctcaagtacg ttgaattcga tgctaggaag taagactgac tcttctagtg cacctgcagg
    14161 tggagttctc atcttactcg ttatcttcat ctttccagca aacgcaactc ctctgcaact
    14221 tagctataaa gatctccaac gagtcgactg gacaggaggc tggctgtcat tagcggctat
    14281 aactcttctc atatttgcct tacaaagtgg tggcagcgag tatgaatgga acagtgctcc
    14341 cgtcgtatct acactggtcg gagcaggcac atgcttggta ctctttctcc tatacgaggc
    14401 tttcctcggt cgtgggtcca aagacgatca aacacttcct atatatccga ctcggcttct
    14461 gaaaaattgg agactcaatg ctgccttact gtcggtatgt ccttggactt gcattaactt
    14521 gactgactag ggacagaacg tcactcatca ttggcttccc attcatgata acgatcatac
    14581 aactcccgca aagtttccaa attgtagcct cgcggtctgc agtacgcgca gggatcgata
    14641 tgattccact tctcattttc tcggccctcg gttccggtct tggtggcgca ctttgctctc
    14701 ggaaacccat cgagcgcgag ctactggcaa tctcgttcat gctccagttg ataggattag
    14761 gtcccctcta ctctgtgcga ctgactggtg cagctcttgc gagtcactat gtctacgaat
    14821 cccttgctgg cctgggtttt gggctatcac taagcagcat aaccatcgtg gcgcgacgtt
    14881 ctgtcgacga ggatgatctc tctgtcgcta tgggacttac cacacagctg cgtgttcttg
    14941 ggggcctaat cgggattggt gctgcccaaa gcctgctcaa cagggtcaca gggcgggacc
    15001 tgaagagtta tgtcagcgca gaagtccgcg cacgcctaca gagctcagtc gagaatattc
    15061 ataccctttc caaagaacaa caagacactg ttcggcgttt ttacggacgt gggtaccggc
    15121 aacagattat tgtctcgtta tcgacggcag cgctgggact tgtacttgct ctggcaatga
    15181 cggctacacg cggagcaacg gtagaaaagg atacaccgga tgagacaccg agcgaggata
    15241 gcgaacttcg tagactgccg cctctggaaa cttatcagat cgatcaagtt ggccacgttt
    15301 ccgatcctag cgatgttggg tcgctcacga ctgctcctac tatccgaaac cctaaaaaca
    15361 gtccacaaga gctgcttgaa tctgtgtgac tgtagttaga tagccgtaca agttagaatg
    15421 aaaccatcgt cgcccggact ctttccccat ttttcaaata cgcaga
//
